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Medical News Today: Could targeting gut bacteria prevent autoimmunity?
A gut bacterium called Enterococcus gallinarum can drive autoimmune diseases such as lupus, new research finds. Could targeting it offer a new treatment? (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 9, 2018 Category: Consumer Health News Tags: Immune System / Vaccines Source Type: news

Monoclonal antibodies crucial to fighting emerging infectious diseases, say NIH officials
Special antibodies have shown promise in the fight against cancer and autoimmune diseases. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - March 8, 2018 Category: American Health Source Type: news

The enemy within: Gut bacteria drive autoimmune disease
Bacteria in the small intestines can travel to other organs and trigger an autoimmune response, though vaccines or antibiotics can suppress this reaction. (Source: Yale Science and Health News)
Source: Yale Science and Health News - March 8, 2018 Category: Universities & Medical Training Source Type: news

Cyteir Therapeutics Secures $29 Million Series B to Advance Novel, Molecularly Targeted Therapies for Cancer and Autoimmune Diseases
Lead investor Venrock joined by Celgene, Lightstone and DROIA Markus Renschler, M.D., joins as CEO, from Celgene Financing proceeds will be used to advance RAD51 inhibitor toward the clinic and expand small-molecule synthetic lethality platform for o... Biopharmaceuticals, Oncology, Venture Capital Cyteir Therapeutics, RAD51 transport (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 8, 2018 Category: Pharmaceuticals Source Type: news

Surprise finding could lead to new MS treatments
(University of Alberta Faculty of Medicine& Dentistry) A discovery led by scientists at the University of Alberta and McGill University is providing hope of a new therapeutic target in Multiple Sclerosis (MS) patients that could one day be used to prevent the symptoms and progression of the disease. By removing a protein called calnexin in mice, researchers found the mice were provided with full protection from the mouse model of MS -- known as experimental autoimmune encephalomyelitis (EAE). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 8, 2018 Category: International Medicine & Public Health Source Type: news

For nanomedicine, cell sex matmonoclonal antibodies crucial to fighting emerging infectious diseases say NIAID officials
(NIH/National Institute of Allergy and Infectious Diseases) Monoclonal antibodies (mAbs) -- preparations of a type of antibody designed to bind to a single target -- have shown promise in the fight against cancer and autoimmune diseases. They also may play a role in future battles against emerging infectious disease outbreaks, according to an NEJM article by NIAID scientists. The article outlines the potential uses for mAbs as treatments for infectious diseases, as prevention for protecting at-risk individuals, and slowing disease outbreaks (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 8, 2018 Category: Infectious Diseases Source Type: news

Monoclonal antibodies crucial to fighting emerging infectious diseases, say NIAID officials
(NIH/National Institute of Allergy and Infectious Diseases) Monoclonal antibodies (mAbs) -- preparations of a type of antibody designed to bind to a single target -- have shown promise in the fight against cancer and autoimmune diseases. They also may play a role in future battles against emerging infectious disease outbreaks, according to an NEJM article by NIAID scientists. The article outlines the potential uses for mAbs as treatments for infectious diseases, as prevention for protecting at-risk individuals, and slowing disease outbreaks (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 8, 2018 Category: Infectious Diseases Source Type: news

New funding for specialist arthritis research centres
Arthritis Research UK has announced new funding for three of its flagship research centres. Since launching in 2012, the centres, which specialise in adolescent rheumatology and osteoarthritis, have already laid the foundation for clinical advances. The new funding will run for five years and will help the researchers continue to explore how arthritis develops and potential ways to treat and prevent the condition.Arthritis Research UK supports exceptional research that aims to prevent the onset of arthritis, develop a cure for arthritis and transform the lives people living with the condition. As part of this, the charity ...
Source: Arthritis Research UK - March 8, 2018 Category: Rheumatology Source Type: news

Translocation of a gut pathobiont drives autoimmunity in mice and humans
Despite multiple associations between the microbiota and immune diseases, their role in autoimmunity is poorly understood. We found that translocation of a gut pathobiont, Enterococcus gallinarum, to the liver and other systemic tissues triggers autoimmune responses in a genetic background predisposing to autoimmunity. Antibiotic treatment prevented mortality in this model, suppressed growth of E. gallinarum in tissues, and eliminated pathogenic autoantibodies and T cells. Hepatocyte–E. gallinarum cocultures induced autoimmune-promoting factors. Pathobiont translocation in monocolonized and autoimmune-prone mice indu...
Source: ScienceNOW - March 8, 2018 Category: Science Authors: Manfredo Vieira, S., Hiltensperger, M., Kumar, V., Zegarra-Ruiz, D., Dehner, C., Khan, N., Costa, F. R. C., Tiniakou, E., Greiling, T., Ruff, W., Barbieri, A., Kriegel, C., Mehta, S. S., Knight, J. R., Jain, D., Goodman, A. L., Kriegel, M. A. Tags: Immunology, Medicine, Diseases reports Source Type: news

New funding for specialist arthritis research centres
Arthritis Research UK has announced new funding for three of its flagship research centres. Since launching in 2012, the centres, which specialise in adolescent rheumatology and osteoarthritis, have already laid the foundation for clinical advances. The new funding will run for five years and will help the researchers continue to explore how arthritis develops and potential ways to treat and prevent the condition.Arthritis Research UK supports exceptional research that aims to prevent the onset of arthritis, develop a cure for arthritis and transform the lives people living with the condition. As part of this, the charity ...
Source: Arthritis Research UK - March 8, 2018 Category: Rheumatology Source Type: news

What are Indications for Allergen-specific Immunotherapy?
Discussion Allergen-specific immunotherapy (AIT) is a disease modifying treatment for allergic disease. Sometimes referred to as desensitization, the premise is to expose the patient to small but regular amounts of a specific antigen thereby building tolerance within the patient to the allergen. AIT is often underused because of safety concerns and lack of appropriately trained health care providers and facilities to safely carry out AIT treatment. There are 4 main AIT treatments options currently: SCIT – subcutaneous immunotherapy Allergen is injected into the subcutaneous skin “Shots are effective in treati...
Source: PediatricEducation.org - March 5, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Researchers Identify Five Different Types of Diabetes, Not Just Type 1 and Type 2
For many years, diabetes cases have largely been classified as either type 1 or type 2. But a new study suggests that there may actually be five different types of the disease—some of which may be more dangerous than others. A new classification system could help doctors identify the people most at risk for complications, the study authors say, and could pave the way for more personalized and effective treatments. The research article, published in The Lancet: Diabetes & Endocrinology, calls attention to the need for an updated diabetes classification system. The current system “has not been much updated du...
Source: TIME: Health - March 2, 2018 Category: Consumer Health News Authors: Amanda MacMillan Tags: Uncategorized healthytime medicine onetime Source Type: news

A diagnosis you can ’t afford to miss
4 out of 5 stars Antibody-Mediated Encephalitis. Dalmau J, Graus F. N Engl J Med 2018 Mar 1;378:840-851. Reference TPR has posted before about anti-NMDA receptor encephalitis, a must-know, can’t-miss, humbling diagnosis that is distressingly easy to overlook. Although it is not a toxicologic condition, all toxicologists and emergency physicians should be thoroughly familiar with its presentation and clinical course. Let me explain why. NMDAR encephalitis often begins with behavioral changes, mood swings, and memory deficits in relatively young patients. According to this somewhat technical but excellent review, ...
Source: The Poison Review - March 2, 2018 Category: Toxicology Authors: Leon Gussow Tags: Medical anbitody-mediated encephalitis anti-NMDA receptor encephalitis brain on fire diagnosis Source Type: news

Managing Rheumatic Conditions in Pregnancy Managing Rheumatic Conditions in Pregnancy
Dr Kevin Deane reviews new data on treatment outcomes during pregnancy in women with autoimmune diseases.Medscape Rheumatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 2, 2018 Category: Consumer Health News Tags: Rheumatology Viewpoint Source Type: news

AstraZeneca Spins Off Autoimmune Drugs Into New Biotech Company AstraZeneca Spins Off Autoimmune Drugs Into New Biotech Company
AstraZeneca is spinning off six early-stage experimental drugs into a new $250 million standalone biotech company focused on severe autoimmune diseases.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 1, 2018 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Drug for Stills Disease Shows Promise in Phase 2 Trial
Patients with the rare autoimmune condition, highlighted in the Oscar-nominated film The Big Sick, currently have limited treatment options. (Source: The Scientist)
Source: The Scientist - March 1, 2018 Category: Science Tags: Daily News,The Scientist Source Type: news

MedImmune to create stand-alone company for early-stage inflammation and autoimmunity biologics
AstraZeneca today announced that its global biologics research and development arm, MedImmune, is spinning out six molecules from its early-stage inflammation and autoimmunity programmes into an independent biotech company, Viela Bio. The new company will focus on developing medicines for severe autoimmune diseases by targeting the underlying causes of each disease. (Source: World Pharma News)
Source: World Pharma News - February 28, 2018 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

AstraZeneca spins off autoimmune drugs into new biotech company
LONDON (Reuters) - AstraZeneca is spinning off six early-stage experimental drugs into a new $250 million standalone biotech company focused on severe autoimmune diseases. (Source: Reuters: Health)
Source: Reuters: Health - February 28, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Ignoring Your Emotions Is Bad for Your Health. Here ’s What to Do About It
Modern life is full of emotional challenges. The pressure to succeed, need to “keep up,” fear of missing out and desire for good relationships and work satisfaction can all evoke volatile combinations of emotions. However, what we learn in our society is not how to work with our emotions, but how to block and avoid them. We do it quite well: Between alcohol use, prescription drug use and screen time, there are a multitude of ways to avoid our feelings. When we do acknowledge them, we swat them away with mantras learned since childhood. (“Mind over matter,” “get a grip” and “suck it...
Source: TIME: Health - February 27, 2018 Category: Consumer Health News Authors: Hilary Jacobs Hendel Tags: Uncategorized healthytime Mental Health/Psychology Source Type: news

Self-reported childhood maltreatment, lifelong traumatic events and mental disorders in American and Israeli rheumatoid arthritis patients - Merdler-Rabinowicz R, Hassidim A, Hellou R, Merdler I, H äuser W, Ablin JN.
OBJECTIVES: Psychological stress is thought to play a major role in the development and exacerbation of autoimmune diseases in general, as well as in rheumatoid arthritis (RA) in particular. The aims of the current study are to compare retrospective self-r... (Source: SafetyLit)
Source: SafetyLit - February 26, 2018 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

WATCH: What you need to know about Graves' disease
It's an autoimmune disorder in which the body attacks the thyroid gland cells. (Source: ABC News: Health)
Source: ABC News: Health - February 22, 2018 Category: Consumer Health News Tags: Health Source Type: news

NIH program to accelerate therapies for arthritis, lupus releases first datasets
(NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases) Datasets characterizing individual cells in rheumatoid arthritis and systemic lupus erythematosus disease tissue from the Accelerating Medicines Partnership for Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Phase I study are now available to the research community. Scientists from across the biomedical research community can access the AMP RA/SLE datasets to explore important research questions about these autoimmune conditions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2018 Category: International Medicine & Public Health Source Type: news

'Icebreaker' protein opens genome for t cell development, Penn researchers find
(University of Pennsylvania School of Medicine) Researchers describe the role of a transcription factor called TCF-1 in targeting the condensed chromatin and regulating the availability of genome sequences in T-cell development. The new connection between TCF-1 and chromatin will aid in developing new therapies using epigenetic drugs to alter T-cell fate in cancer, autoimmune disorders, and infectious diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 20, 2018 Category: Cancer & Oncology Source Type: news

DIY faecal transplants carry risks including HIV and hepatitis, warn experts
Faecal transplants have been used in medical settings to tackle superbugs, but following YouTube videos at home is too risky, say researchersConcerns have been raised about the growing trend for DIY faecal transplants, with experts fearing such attempts could put individuals at an increased risk of HIV and hepatitis as well as conditions ranging from Parkinson ’s and multiple sclerosis to obesity and sleep disorders.Thetransfer of faeces from one human to another has gained attention as a growing number of studies have suggested links between microbes in the gut anda host of health problems, from autoimmune diseases ...
Source: Guardian Unlimited Science - February 15, 2018 Category: Science Authors: Nicola Davis in Austin Tags: Microbiology Human biology Infectious diseases Medical research Science Health Source Type: news

Shielding EMFs found to reduce 90% of symptoms in people with autoimmune disease
(Natural News) Revolutionary research has shown that hindering exposure to electromagnetic fields (EMF) produces significant symptom changes in 90 percent of patients with autoimmune disease. This provides proof that radiation poses innumerable health risks to humans. A recent study that was published in the peer-reviewed journal Immunologic Research titled “Electrosmog and Autoimmune Disease” enlightens people... (Source: NaturalNews.com)
Source: NaturalNews.com - February 15, 2018 Category: Consumer Health News Source Type: news

New technology enables identification of biomarkers for a wide range of diseases
(Medical College of Georgia at Augusta University) Scientists have developed a way to identify biomarkers for a wide range of diseases by assessing the antibodies we are making to the complex sugars coating our cells.The new, highly sensitive Luminex Multiplex Glycan Array enables the kind of volume needed to establish associations between antibody levels in our blood to these complex sugars, or glycans, and conditions from cancer to autoimmune disease and dementia, they report in the journal Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2018 Category: International Medicine & Public Health Source Type: news

Local MPs and MSP visit prestigious Glasgow research centre
Alison Thewliss MP, Bill Kidd MSP and Carol Monaghan MP all visited theArthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence (RACE), at the University of Glasgow on Friday (9 February), to learn about the impact of arthritis on their local constituents and the current investment in arthritis research across Scotland.The centre, which is funded by Arthritis Research UK, investigates the causes of and potential treatments forrheumatoid arthritis, a painful autoimmune disease which affects over 400,000 people in the UK. Data analysed by the charity reveals that nearly 37,000 people in Scotland...
Source: Arthritis Research UK - February 12, 2018 Category: Rheumatology Source Type: news

Local MPs and MSP visit prestigious Glasgow research centre
Alison Thewliss MP, Bill Kidd MSP and Carol Monaghan MP all visited theArthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence (RACE), at the University of Glasgow on Friday (9 February), to learn about the impact of arthritis on their local constituents and the current investment in arthritis research across Scotland.The centre, which is funded by Arthritis Research UK, investigates the causes of and potential treatments forrheumatoid arthritis, a painful autoimmune disease which affects over 400,000 people in the UK. Data analysed by the charity reveals that nearly 37,000 people in Scotland...
Source: Arthritis Research UK - February 12, 2018 Category: Rheumatology Source Type: news

Center for autoimmune and inflammation disorders named for emeritus professor Paul Phillips, MD
The Phillips Center focuses on the metabolic control of autoimmunity, inflammation, immune health and supports new collaborative initiatives in autoimmunity and inflammatory diseases. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - February 8, 2018 Category: Universities & Medical Training Source Type: news

A new study finds homeopathic treatments improve vitiligo, a condition where skin loses its pigment
(Natural News) A case report found that homeopathy could improve vitiligo, an autoimmune disease that causes the skin to lose its melanin pigment. The case report was led by a team of researchers from the Centre for Classical Homeopathy in Bangalore, India who looked at a series of 14 cases of vitiligo that involved treatment with... (Source: NaturalNews.com)
Source: NaturalNews.com - February 4, 2018 Category: Consumer Health News Source Type: news

Drinking milk, eating beef could cause arthritis
Researchers at the University of Central Florida discovered that bacteria commonly found in milk and beef is linked to rheumatoid arthritis, an autoimmune and inflammatory disease. (Source: the Mail online | Health)
Source: the Mail online | Health - January 31, 2018 Category: Consumer Health News Source Type: news

Biased signaling by thyroid-stimulating hormone receptor-specific antibodies determines thyrocyte survival in autoimmunity
The thyroid-stimulating hormone receptor (TSHR) is a heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptor (GPCR). Autoimmune hyperthyroidism, commonly known as Graves’ disease (GD), is caused by stimulating autoantibodies to the TSHR. We previously described TSHR-specific antibodies (TSHR-Abs) in GD that recognize linear epitopes in the cleavage region of the TSHR ectodomain (C-TSHR-Abs) and induce thyroid cell apoptosis instead of stimulating the TSHR. We found that C-TSHR-Abs entered the cell through clathrin-mediated endocytosis but did not trigger endosomal maturation and fai...
Source: Signal Transduction Knowledge Environment - January 23, 2018 Category: Science Authors: Morshed, S. A., Ma, R., Latif, R., Davies, T. F. Tags: STKE Research Articles Source Type: news

Guanabenz inhibits TLR9 signaling through a pathway that is independent of eIF2{alpha} dephosphorylation by the GADD34/PP1c complex
Endoplasmic reticulum (ER) stress triggers or amplifies inflammatory signals and cytokine production in immune cells. Upon the resolution of ER stress, the inducible phosphatase 1 cofactor GADD34 promotes the dephosphorylation of the initiation factor eIF2α, thereby enabling protein translation to resume. Several aminoguanidine compounds, such as guanabenz, perturb the eIF2α phosphorylation-dephosphorylation cycle and protect different cell or tissue types from protein misfolding and degeneration. We investigated how pharmacological interference with the eIF2α pathway could be beneficial to treat autoinfl...
Source: Signal Transduction Knowledge Environment - January 23, 2018 Category: Science Authors: Perego, J., Mendes, A., Bourbon, C., Camosseto, V., Combes, A., Liu, H., Manh, T.-P. V., Dalet, A., Chasson, L., Spinelli, L., Bardin, N., Chiche, L., Santos, M. A. S., Gatti, E., Pierre, P. Tags: STKE Research Articles Source Type: news

Fibre-rich foods 'may help protect against joint diseases and improve bone health'
People eating adiet featuring plenty of fibre-rich foods such as muesli may experience better bone health and a lower risk of autoimmune diseases. This is according to a new study from Germany's Friedrich-Alexander-Universität Erlangen-Nürnberg, which has shed light on how a healthy diet rich in fibre can alter the behaviour of intestinal bacteria in a way that has a positive impact on chronic inflammatory joint diseases. How does fibre-rich food improve bone health? Published in the journal Nature Communications, the study looked at mice to examine the effect that diet has on the composition of intestinal ba...
Source: Arthritis Research UK - January 22, 2018 Category: Rheumatology Source Type: news

Efficacy of antibody targeting Devic's disease proven in new animal model
(Osaka University) Neuromyelitis optica (NMO) is an autoimmune disease associated with NMO immunoglobulin G (NMO-IgG). A cure for NMO remains elusive. Osaka University researchers recently established a localized NMO rat model by injecting NMO-IgG into the spinal cord, and assessed the efficacy of anti-repulsive guidance molecule-a (RGMa) antibody in treating NMO. They found anti-RGMa antibody delayed the onset and attenuated the severity of clinical symptoms of NMO, suggesting that humanized anti-RGMa antibody is a potentially valid therapeutic approach for NMO. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 18, 2018 Category: International Medicine & Public Health Source Type: news

Genomics reveals key macrophages' involvement in systemic sclerosis
(Duke-NUS Medical School) A new international study has made an important discovery about the key role of macrophages, a type of immune cell, in systemic sclerosis (SSc), a chronic autoimmune disease which currently has no cure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 18, 2018 Category: International Medicine & Public Health Source Type: news

Scientists shed light on a key molecular mechanism of autoimmune and inflammatory diseases
(VIB (the Flanders Institute for Biotechnology)) An international team of researchers led by prof. Savvas Savvides (VIB-UGent Center for Inflammation Research) has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease. Focusing on the immunomodulatory cytokine IL-23 they discovered that its pro-inflammatory activity, which underlies a wide range of inflammatory diseases, critically depends on structural activation of the cytokine by its receptor, IL-23R. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 17, 2018 Category: International Medicine & Public Health Source Type: news

Concert Pharma shares hit low note on patent challenge denial
Lexington-based Concert Pharmaceuticals Inc. lost more than a quarter of its market value — around $150 million — Friday after news that the U.S. Patent and Trademark Office didn’t grant its petition challenging a patent for a drug to treat an autoimmune skin disease. Concert (Nasdaq: CNCE), a 12-year-old biotech with 66 employees, said Friday morning that the Patent Trial and App eal Board has decided not to grant a post grant review petition seeking to invalidate the patent for ruxolitinib,… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - January 16, 2018 Category: American Health Authors: Don Seiffert Source Type: news

Student hospitalized for 106 days after eating a sandwich
Alec Hebblethwaite, 14, of Osage, Missouri hospitalized for nearly four months after damaging his esophagus while eating a sandwich. It transpired his reaction was caused by a rare autoimmune disease. (Source: the Mail online | Health)
Source: the Mail online | Health - January 15, 2018 Category: Consumer Health News Source Type: news

Effects of sport climbing on multiple sclerosis - Steimer J, Weissert R.
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease of the central nervous system (CNS) with different types of disease courses (relapsing-remitting, secondary-progressive, primary progressive) that leads to physical as well as mental di... (Source: SafetyLit)
Source: SafetyLit - January 15, 2018 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

NIDCR Autotherapies Symposium | Thurs., Jan. 25, 8:00 a.m.-12:00 p.m.
Having trouble viewing this email? View it as a Web page.   NIDCR invites you to a scientific symposium: "Autotherapies: Enhancing Our Innate Healing Capacity"  Thursday, January 25, 8:00 am-12:00 pm Lipsett Amphitheater in the NIH Clinical Center (Building 10)NIH Campus, Bethesda, Md. Autotherapies are treatments based on the body's natural ability to heal and protect itself. For example, immunotherapy harnesses the body’s immune cells to fight c...
Source: NIDCR Science News - January 11, 2018 Category: Dentistry Source Type: news

Dr. Helen Genova awarded grant for novel emotional processing study in multiple sclerosis
(Kessler Foundation) Helen Genova, Ph.D., Assistant Director of Neuropsychology& Neuroscience Research at Kessler Foundation, has been awarded a $44,000 grant from the National Multiple Sclerosis Society. The grant funds her research on emotional processing deficits in people with multiple sclerosis, an autoimmune degenerative disease of the central nervous system associated with significant behavioral and emotional sequelae. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 10, 2018 Category: International Medicine & Public Health Source Type: news

Effects of estrogen treatment combat multiple sclerosis in mice
FINDINGSA study by UCLA researchers reveals the cellular basis for how the hormone estrogen protects against damage to the central nervous system in women with multiple sclerosis, or MS. The researchers found that estrogen treatment exerts positive effects on two types of cells during disease — immune cells in the brain as well as cells called oligodendrocytes.BACKGROUNDUCLADr. Rhonda VoskuhlMultiple sclerosis is a chronic autoimmune, neurodegenerative disease marked by visual impairment, weakness and sensory loss, as well as cognitive decline. These symptoms emerge when inflammatory immune cells destroy the myelin s...
Source: UCLA Newsroom: Health Sciences - January 10, 2018 Category: Universities & Medical Training Source Type: news

Researchers find potential path to repair nerves damaged by multiple sclerosis
FINDINGSA UCLA study found that gene expression in specific cells and in specific regions of the body can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. Gene expression is the process by which genetic instructions are used to synthesize gene products, such as proteins, which go on to perform essential functions.For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.BACKGROUNDMultiple sclerosis is an autoimmune, neurodegenerative disease characterized...
Source: UCLA Newsroom: Health Sciences - January 9, 2018 Category: Universities & Medical Training Source Type: news

Inova Diagnostics Receives FDA Clearance for the First Fully Automated, Random Access Calprotectin Test
SAN DIEGO, Jan. 3, 2018 -- (Healthcare Sales & Marketing Network) -- Inova Diagnostics, a world leader in autoimmune disease diagnostic systems and reagents for the clinical laboratory, is proud to announce the clearance of QUANTA Flash® Calprotectin ... Diagnostics, FDA Inova Diagnostics, Calprotectin, inflammatory bowel disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 3, 2018 Category: Pharmaceuticals Source Type: news

Immunobiologist Carla Rothlin spurs the body to repair itself
Rothlin has devoted much of her research to properties of the immune system —which promotes tissue repair but also can degrade health through autoimmune disease. (Source: Yale Science and Health News)
Source: Yale Science and Health News - January 2, 2018 Category: Universities & Medical Training Source Type: news

Healthy diet found to help reduce, delay symptoms of MS
(Natural News) A diet that incorporates “fruits, vegetables, and whole grains” has countless benefits, from improved overall health to weight loss. But according to a recent study, patients with multiple sclerosis (MS) can also reduce their symptoms with a healthy diet. Multiple sclerosis, an autoimmune disease, develops when an individual’s immune system accidentally attacks its own central nervous... (Source: NaturalNews.com)
Source: NaturalNews.com - December 24, 2017 Category: Consumer Health News Source Type: news

The Heart in Rheumatic, Autoimmune and Inflammatory Diseases The Heart in Rheumatic, Autoimmune and Inflammatory Diseases
This new book is likely to become a standard reference for cardiologists and rheumatologists caring for patients with cardiovascular manifestations of inflammatory diseases, according to the reviewer.European Heart Journal (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 21, 2017 Category: Allergy & Immunology Tags: Cardiology Journal Article Source Type: news

From Iran To CEO Of A Biotech Startup, Bioniz, With No Revenue But A $400 Million Valuation
Nazli Azimi founded Bioniz Therapeutics, where she's developing new types of drugs to fight cancer and autoimmune diseases like celiac and alopecia. Her theory: attack so-called cytokines, the multiple proteins that block immune pathways. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 20, 2017 Category: Pharmaceuticals Authors: Susan Adams, Forbes Staff Source Type: news