LumiThera Announces Top Line Data in the European Multi-Center, LIGHTSITE II Clinical Study to Treat Dry Age-Related Macular Degeneration
SEATTLE, April 7, 2021 -- (Healthcare Sales & Marketing Network) -- LumiThera Inc., a commercial stage medical device company delivering photobiomodulation (PBM) treatment for ocular disorders and disease, today announced positive findings in its LIGHTSIT... Devices, Ophthalmology LumiThera , photobiomodulation, Age-Related Macular Degeneration (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 7, 2021 Category: Pharmaceuticals Source Type: news

Lab model offers hope for macular degeneration patients
(University of Rochester) University of Rochester researchers have created a 3D lab model using patient-derived tissues that mimics the areas of the retina affected in age-related macular degeneration (AMD), which affects an estimated 196 million people. They believe this could lead to finding specific drugs for individual patients to treat a disease that currently has no cure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 29, 2021 Category: International Medicine & Public Health Source Type: news

Gene therapy trial for age-related macular degeneration now open at Columbia
(Columbia University Irving Medical Center) A clinical trial to test a gene therapy for some patients with dry age-related macular degeneration -- a leading cause of blindness in the United States -- is underway at Columbia and NewYork-Presbyterian. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 9, 2021 Category: International Medicine & Public Health Source Type: news

New Hope for Better Macular Degeneration Treatments
A number of new treatments for age-related macular degeneration (AMD), a progressive eye disease, are under development. (Source: WebMD Health)
Source: WebMD Health - February 22, 2021 Category: Consumer Health News Source Type: news

New Hope for Better Treatments Against Macular Degeneration
MONDAY, Feb. 22, 2021 -- A number of new treatments for age-related macular degeneration (AMD), a progressive eye disease, are under development. AMD is a leading cause of vision loss in older people. About 11 million Americans have AMD, which... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 22, 2021 Category: General Medicine Source Type: news

New phase III data show Roche ’s faricimab is the first investigational injectable eye medicine to extend time between treatments up to four months in two leading causes of vision loss, potentially reducing treatment burden for patients
Basel, 12 February 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from four phase III studies of its investigational bispecific antibody, faricimab, for the treatment of diabetic macular edema (DME) and neovascular or “wet” age-related macular degeneration (nAMD). The studies consistently showed that faricimab, given at intervals of up to four months, offered non-inferior vision gains compared to aflibercept, given every two months. Approximately half of people eligible for extended dosing with faricimab were able to be treated every four months in the first year in the YOSEMITE and ...
Source: Roche Investor Update - February 12, 2021 Category: Pharmaceuticals Source Type: news

New phase III data show Roche ’s faricimab is the first investigational injectable eye medicine to extend time between treatments up to four months in two leading causes of vision loss, potentially reducing treatment burden for patients
Basel, 12 February 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from four phase III studies of its investigational bispecific antibody, faricimab, for the treatment of diabetic macular edema (DME) and neovascular or “wet” age-related macular degeneration (nAMD). The studies consistently showed that faricimab, given at intervals of up to four months, offered non-inferior vision gains compared to aflibercept, given every two months. Approximately half of people eligible for extended dosing with faricimab were able to be treated every four months in the first year in the YOSEMITE and ...
Source: Roche Media News - February 12, 2021 Category: Pharmaceuticals Source Type: news

Ambient Air Pollution Tied to Age-Related Macular Degeneration Ambient Air Pollution Tied to Age-Related Macular Degeneration
People with higher exposure to ambient air pollution are at increased risk for age-related macular degeneration and changes in retinal thickness, a UK study suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 1, 2021 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Air Pollution May Up Risk for Age-Related Macular Degeneration
WEDNESDAY, Jan. 27, 2021 -- Greater exposure to fine ambient particulate matter with an aerodynamic diameter
Source: Drugs.com - Pharma News - January 27, 2021 Category: Pharmaceuticals Source Type: news

Johnson & Johnson Reports 2020 Fourth-Quarter and Full Year Results
New Brunswick, N.J. (January 26, 2021) – Johnson & Johnson (NYSE: JNJ) today announced results for fourth-quarter and full year 2020. “Our notable full year performance reflects the continued confidence from patients, physicians, customers and consumers in our life-enhancing products and medicines, particularly throughout the COVID-19 pandemic,” said Alex Gorsky, Chairman and Chief Executive Officer. “I’m incredibly proud of our Johnson & Johnson teams around the world for going above and beyond to meet stakeholder needs. These efforts, and our commitment to families around the world a...
Source: Johnson and Johnson - January 26, 2021 Category: Pharmaceuticals Tags: Our Company Source Type: news

Roche ’s faricimab meets primary endpoint in two global phase III studies and shows potential to extend time between treatments up to 16 weeks for people with neovascular age-related macular degeneration
Basel, 25 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from two identically designed global phase III studies, TENAYA and LUCERNE, evaluating its investigational bispecific antibody, faricimab, in people living with neovascular or “wet” age-related macular degeneration (nAMD). Both studies met their primary endpoint and showed that people receiving faricimab injections at fixed intervals of up to every 16 weeks achieved visual acuity outcomes that were non-inferior to those receiving aflibercept injections every eight wee ks. Nearly half (45%) of people in both stud...
Source: Roche Investor Update - January 25, 2021 Category: Pharmaceuticals Source Type: news

Roche ’s faricimab meets primary endpoint in two global phase III studies and shows potential to extend time between treatments up to 16 weeks for people with neovascular age-related macular degeneration
Basel, 25 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from two identically designed global phase III studies, TENAYA and LUCERNE, evaluating its investigational bispecific antibody, faricimab, in people living with neovascular or “wet” age-related macular degeneration (nAMD). Both studies met their primary endpoint and showed that people receiving faricimab injections at fixed intervals of up to every 16 weeks achieved visual acuity outcomes that were non-inferior to those receiving aflibercept injections every eight wee ks. Nearly half (45%) of people in both stud...
Source: Roche Media News - January 25, 2021 Category: Pharmaceuticals Source Type: news

Air pollution linked to higher risk of sight loss from AMD
(University College London) Air pollution is linked to a heightened risk of progressive and irreversible sight loss, known as age related macular degeneration (AMD), reveals a large long term study led by UCL researchers, published in the British Journal of Ophthalmology. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 25, 2021 Category: International Medicine & Public Health Source Type: news

Roche ’s faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness
Basel, 21 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from two identically designed global phase III studies, YOSEMITE and RHINE, evaluating its investigational bispecific antibody, faricimab, in people living with diabetic macular edema (DME). Both studies met their primary endpoint and showed that faricimab given every eight weeks and at personalised dosing intervals of up to 16 weeks demonstrated non-inferior visual acuity gains compared to aflibercept given every eight weeks. Faricimab was generally well-tolerated, with no new safety signals identified. The studies each h...
Source: Roche Media News - December 21, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s faricimab meets primary endpoint and shows strong durability across two global phase III studies for diabetic macular edema, a leading cause of blindness
Basel, 21 December 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from two identically designed global phase III studies, YOSEMITE and RHINE, evaluating its investigational bispecific antibody, faricimab, in people living with diabetic macular edema (DME). Both studies met their primary endpoint and showed that faricimab given every eight weeks and at personalised dosing intervals of up to 16 weeks demonstrated non-inferior visual acuity gains compared to aflibercept given every eight weeks. Faricimab was generally well-tolerated, with no new safety signals identified. The studies each h...
Source: Roche Investor Update - December 21, 2020 Category: Pharmaceuticals Source Type: news

Development of the first biohybrid artificial retina built with silk fibroin and retinal cells.
(Universidad Complutense de Madrid) An international research led by the Complutense University of Madrid has taken a further step to solve Age-related Macular Degeneration (AMD)-derived blidness problem with the development of the first biohybrid artificial retina built with silk fibroin and retinal cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2020 Category: International Medicine & Public Health Source Type: news

New insights about age-related macular degeneration could spur better treatments
(Massachusetts General Hospital) Experiments in a mouse model have uncovered mechanisms involved in abnormal blood vessel formation in " wet " age-related macular degeneration. Certain inflammatory pathways and proteins may be attractive therapeutic targets for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2020 Category: International Medicine & Public Health Source Type: news

Janssen Acquires Rights to Novel Gene Therapy, Pioneering Treatment Solutions for Late-Stage Age-Related Macular Degeneration
RARITAN, NJ, December 2, 2020 – Janssen Pharmaceuticals, Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson, today announced the acquisition of rights to Hemera Biosciences, LLC’s investigational gene therapy HMR59, administered as a one-time, outpatient, intravitreal injection to help preserve vision in patients with geographic atrophy, a late-stage and severe form of age-related macular degeneration (AMD). Financial terms of the transaction with Hemera Biosciences, a privately-owned biotechnology company, are not being disclosed. Patients with AMD often have low levels of CD59, a prote...
Source: Johnson and Johnson - December 2, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Ranibizumab Biosimilar Shows Equivalent Efficacy to Branded Drug for Neovascular AMD Ranibizumab Biosimilar Shows Equivalent Efficacy to Branded Drug for Neovascular AMD
In a phase 3 study, the ranibizumab biosimilar SB11 demonstrated equivalent efficacy and similar safety and immunogenicity profiles compared with ranibizumab for patients with neovascular age-related macular degeneration (nAMD).Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 1, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Late-Breaking 12-Month Data of Investigational RPGR Gene Therapy Shows Statistically Significant and Continued Vision Improvement in Patients with X-Linked Retinitis Pigmentosa
RARITAN, N.J., November 13, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today new 12-month data from the ongoing Phase 1/2 trial (NCT03252847) of its investigational gene therapy for inherited retinal disease X-linked retinitis pigmentosa (XLRP). The data showed that low and intermediate doses were well-tolerated and continued to demonstrate statistically significant sustained or increased vision improvement across multiple metrics (mean sensitivity, volumetric and pointwise) and modalities (full-field static perimetry and microperimetry). Data on the novel adeno-associated virus re...
Source: Johnson and Johnson - November 13, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Vitamin D3, Omega-3 Fatty Acids Have No Impact on AMD
FRIDAY, Oct. 30, 2020 -- For initially healthy men and women, supplementation with vitamin D3 and marine omega-3 fatty acids have no significant impact on age-related macular degeneration (AMD) incidence or progression, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 30, 2020 Category: Pharmaceuticals Source Type: news

Anti-VEGF Therapy May Aid Visual Acuity in Some nAMD Patients
MONDAY, Oct. 19, 2020 -- For about 20 percent of patients with neovascular age-related macular degeneration (nAMD), useful visual acuity (VA) is preserved with anti-vascular endothelial growth factor (VEGF) treatment, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 19, 2020 Category: Pharmaceuticals Source Type: news

For Some, Anti-VEFG Treatment Preserves Sight for a Lifetime For Some, Anti-VEFG Treatment Preserves Sight for a Lifetime
Nearly 20% of those who received anti-VEGF treatment for neovascular age-related macular degeneration (nAMD) retained useful visual acuity over their lifetime, a new study finds.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 17, 2020 Category: Pathology Tags: Ophthalmology News Source Type: news

Changes to Anti-VEGF Protocols Questioned in Wet AMD Changes to Anti-VEGF Protocols Questioned in Wet AMD
New research calls into question the benefit of newer injection schedules to prevent vision loss in neovascular age-related macular degeneration.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 14, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Implant Reduces Treatment Burden in Wet Macular Degeneration Implant Reduces Treatment Burden in Wet Macular Degeneration
The administration of ranibizumab with an implant, rather than intravitreal injection, looks promising for neovascular age-related macular degeneration, interim results from a phase 3 study indicate.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Visible Genomics hires clinical advisers to prep for macular degeneration test
The company is preparing to launch a non-invasive genetic eye test that can determine a patient's likelihood of contracting age-related macular degeneration. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 28, 2020 Category: Biotechnology Authors: I-Chun Chen Source Type: news

Parkinson's Drug Levodopa Eyed as Treatment for Severe Macular Degeneration
WEDNESDAY, Sept. 16, 2020 -- A drug long used to treat Parkinson's disease may benefit patients with a severe form of age-related macular degeneration (AMD), a small clinical trial suggests. One of the leading causes of vision loss in older people... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 16, 2020 Category: General Medicine Source Type: news

Levodopa Benefits Neovascular Age-Related Macular Degeneration
TUESDAY, Sept. 15, 2020 -- Levodopa is a safe and well-tolerated treatment for neovascular age-related macular degeneration (nAMD) and improves visual outcomes, according to a study recently published in The American Journal of Medicine. Anna G.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 15, 2020 Category: Pharmaceuticals Source Type: news

Levodopa may improve vision in patients with macular degeneration
(Elsevier) Investigators have determined that treating patients with an advanced form of age-related macular degeneration (AMD) with levodopa, a safe and readily available drug commonly used to treat Parkinson's disease, stabilized and improved their vision. It reduced the number of treatments necessary to maintain vision, and as such, will potentially reduce the burden of treating the disease, financially and otherwise. Their findings appear in The American Journal of Medicine, published by Elsevier. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 10, 2020 Category: International Medicine & Public Health Source Type: news

RegenxBio is growing — and pushing its eye disease treatment through yet another clinical trial
The Rockville biotech is trying to change the game for patients with wet age-related macular degeneration and diabetic retinopathy. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 27, 2020 Category: Biotechnology Authors: Sara Gilgore Source Type: news

Artificial intelligence recognizes deteriorating photoreceptors
(University of Bonn) A software based on artificial intelligence (AI), which was developed by researchers at the Eye Clinic of the University Hospital Bonn, Stanford University and University of Utah, enables the precise assessment of the progression of geographic atrophy (GA), a disease of the light sensitive retina caused by age-related macular degeneration (AMD). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 13, 2020 Category: International Medicine & Public Health Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Media News - July 22, 2020 Category: Pharmaceuticals Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Investor Update - July 22, 2020 Category: Pharmaceuticals Source Type: news

Scientists identify a new drug target for dry age-related macular degeneration
(Sanford Burnham Prebys Medical Discovery Institute) Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that the blood protein vitronectin is a promising drug target for dry age-related macular degeneration (AMD), a leading cause of vision loss in Americans 60 years of age and older. The study, published in the Proceedings of the National Academy of Sciences (PNAS), also holds implications for Alzheimer's and heart disease, which are linked to vitronectin. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 20, 2020 Category: International Medicine & Public Health Source Type: news

Interim Six-Month Data of RPGR Gene Therapy Shows Significant Vision Improvement in Patients Living with X-Linked Retinitis Pigmentosa
Click to Access Audio Press ReleaseRARITAN, NJ, July 17, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today six-month data from the ongoing Phase 1/2 trial (NCT03252847) of its investigational gene therapy for the treatment of inherited retinal disease X-linked retinitis pigmentosa (XLRP). The interim data showed that low and intermediate doses of the investigational adeno-associated virus retinitis pigmentosa GTPase regulator (AAV-RPGR) were generally well-tolerated and indicated significant improvement in vision. Initial data on the novel AAV-RPGR asset, jointly developed with Meir...
Source: Johnson and Johnson - July 17, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Combating drug resistance in age-related macular degeneration
(Baylor College of Medicine) An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for age-related macular degeneration, (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2020 Category: International Medicine & Public Health Source Type: news

Artificial Intelligence Passes Macular Degeneration Test Artificial Intelligence Passes Macular Degeneration Test
A deep-learning system accurately diagnosed age-related macular degeneration in a real-life population in a prospective clinical trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 29, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Nanoscope received NIH support for its first-in-class delivery approach to restore vision
(Nanoscope Technologies) Researchers at Nanoscope ® Technologies, LLC are advancing development of therapeutic gene and delivery platform for treating degenerative eye diseases such as dry age-related macular degeneration (dry-AMD) which affects a significant portion of the global population. Nanoscope was just awarded a multi-million dollar grant from National Eye Institute, a division of the NIH, for advancing the spatially-targeted non-viral spatially-targeted gene delivery platform and Multi-Characteristic Opsin for AMD therapy. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 28, 2020 Category: International Medicine & Public Health Source Type: news

AI Systems Predict the Course of Macular Degeneration AI Systems Predict the Course of Macular Degeneration
Two new artificial intelligence algorithms can predict the development of age-related macular degeneration, researchers say.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 27, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

AI Model Predicts Risk for Age-Related Macular Degeneration
WEDNESDAY, May 27, 2020 -- A new artificial intelligence algorithm can predict risk for age-related macular degeneration (AMD), according to a study published in the April issue of Translational Vision Science and Technology. Alauddin Bhuiyan,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 27, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Investor Update - May 27, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Media News - May 27, 2020 Category: Pharmaceuticals Source Type: news

Study finds unexpected suspect in age-related macular degeneration
(eLife) Scientists have identified an unexpected player in the immune reaction gone awry that causes vision loss in patients with age-related macular degeneration (AMD), according to a new study published today in eLife. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 5, 2020 Category: Biology Source Type: news

I am an eye surgeon but could soon be your doctor in the ICU. I'm terrified
I am fearful for the future, uncertain for how my skills will hold up when put to testCoronavirus – latest updatesSee all our coronavirus coverageI am an ophthalmologist. I am the doctor you see for your cataract surgery, the doctor your grandmother sees to have her age-related macular degeneration checked, the one who prescribed the bedtime drops to slow down your grandfather ’s glaucoma. In the next few weeks I will be the doctor your father sees for his stroke, the doctor who treats your grandmother’s heart failure, the doctor you see in A&E to treat your asthma. Potentially the doctor you meet in ...
Source: Guardian Unlimited Science - April 20, 2020 Category: Science Authors: Selina Khan Tags: Coronavirus outbreak Doctors Society Health Society Professionals Infectious diseases Science NHS Work & careers Guardian Careers Source Type: news

UC Riverside biochemist spins out joint venture company with Atomwise
(University of California - Riverside) Over the past few years, biochemist John Jefferson Perry at the University of California, Riverside, has collaborated on a number of projects with Atomwise Inc., a company that uses artificial intelligence for drug discovery. Now Perry and the company have formed a joint venture called Theia Biosciences. It will focus initially on helping treat age-related macular degeneration through developing small molecule inhibitors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 13, 2020 Category: International Medicine & Public Health Source Type: news

NIH researchers discover tooth-enamel protein in eyes with dry AMD
(NIH/National Eye Institute) A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a study from researchers at the National Eye Institute (NEI). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 13, 2020 Category: International Medicine & Public Health Source Type: news

Wireless Photovoltaic Device Restores Central Visual Sensitivity in Atrophic Age-Related Macular Degeneration Wireless Photovoltaic Device Restores Central Visual Sensitivity in Atrophic Age-Related Macular Degeneration
A wireless photovoltaic device implanted subretinally can restore central visual sensitivity in patients with geographic atrophy, an advanced form of age-related macular degeneration (AMD), according to a first-in-human clinical trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 9, 2020 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Novartis stands by safety of eye drug amid ongoing review
Swiss drugmaker Novartis said on Monday the safety data available for its eye drug Beovu to treat wet age-related macular degeneration (wet AMD) continued to support its use as it conducts a review into the safety of the drug. (Source: Reuters: Health)
Source: Reuters: Health - March 2, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

European Medicines Agency Grants PRIME and Advanced Therapy Medicinal Product Designations to Janssen ’s RPGR Gene Therapy for X-Linked Retinitis Pigmentosa
RARITAN, NJ, March 2, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that the European Medicines Agency (EMA) has granted both PRIME (PRIority MEdicines) and Advanced Therapy Medicinal Product (ATMP) designations to the company’s adeno-associated virus (AAV)-RPGR gene therapy product for the treatment of inherited retinal disease X-linked retinitis pigmentosa (XLRP). PRIME is awarded to increase interactions, optimize development plans and accelerate innovative treatments where there is unmet medical need. Similarly, ATMP status is granted to medicines that are based on gen...
Source: Johnson and Johnson - March 2, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

New discovery has important implications for treating common eye disease
(Trinity College Dublin) Scientists from Trinity College Dublin have made an important discovery with implications for those living with a common, debilitating eye disease (age-related macular degeneration, AMD) that can cause blindness. They have discovered that the molecule TLR2, which recognises chemical patterns associated with infection in the body, also seems to play an important role in the development of retinal degeneration. When TLR2 is removed in model systems, a degree of protection is conferred. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 20, 2020 Category: Biology Source Type: news