Exercise and new nerve cell growth in Alzheimer ’s disease
In a mouse model of Alzheimer ’s disease, access to exercise stimulated the growth of new nerve cells in the brain and reduced memory problems. The findings pave the way for studies in people. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 24, 2018 Category: Consumer Health News Source Type: news

Trial by Fire: Critics Demand That a Huge Sepsis Study Be Stopped
A trial enrolling new patients resembles “ an experiment that would be conducted on laboratory animals, ” one advocacy group said. (Source: NYT Health)
Source: NYT Health - September 24, 2018 Category: Consumer Health News Authors: RONI CARYN RABIN Tags: Sepsis Blood Pressure Septic Shock Clinical Trials National Institutes of Health Source Type: news

NIH supports study of health risks and resilience following Hurricanes Irma and Maria
Research will focus on hurricane-related psychosocial stressors. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 21, 2018 Category: American Health Source Type: news

New Grants To Study Behavioral Interventions for Opioid Addiction and Recovery
Overdose deaths, opioid misuse, addiction to prescription opioids or to illicit drugs such as heroin, and chronic pain management are tough problems that are often related to each other. Together, they form a daunting public health crisis that is of great concern and significance to many in the United States, including the National Center for Complementary and Integrative Health (NCCIH) and much of the National Institutes of Health  (NIH).  (Source: NCCAM Featured Content)
Source: NCCAM Featured Content - September 20, 2018 Category: Complementary Medicine Authors: Robin Boineau, M.D. Source Type: news

How a $2M Grant Could Change the Way Autism Is Diagnosed
Early treatment of autism spectrum disorder (ASD) can significantly improve the lives of affected children and their families, but diagnosing the disorder is often a challenge. A company in Syracuse, NY has developed an epigenetic test that could facilitate the early diagnosis of ASD, however, and in turn accelerate access to treatment. The technology, developed by Quadrant Biosciences, managed to impress a panel of grant reviewers, landing the company a $2 million small business technology transfer (STTR) grant from the National Institutes of Health. The funds are expected to help the company refine the techno...
Source: MDDI - September 20, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news

NIH launches study to test combination antibody treatment for HIV infection
Clinical trial will evaluate whether treatment is safe for people living with HIV. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 19, 2018 Category: American Health Source Type: news

NIH funds study to prevent, treat HIV among adolescents in poor countries
Study seeks to identify high-risk youth and get them into medical care. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 19, 2018 Category: American Health Source Type: news

NIH announces awards for behavioral research on OUD prevention and treatment
Researchers will examine whether select behavioral interventions improve adherence to and retention in MAT. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 19, 2018 Category: American Health Source Type: news

Penn, Rutgers researchers land $18M to study tobacco product marketing
Researchers from the University of Pennsylvania and Rutgers University have received an $18 million grant to study tobacco marketing. The grant was awarded by the Food and Drug Administration and the National Institutes of Health to support research at the Penn's Perelman School and the Rutgers School of Public Health. The funding is part of the ongoing interagency Tobacco Center of Regulatory Science program established by the FDA and NIH. The center is focused on the effects tja advertising,… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 19, 2018 Category: Pharmaceuticals Authors: John George Source Type: news

Is the end of the recombinant DNA Advisory Committee (RAC) a good thing?
(Mary Ann Liebert, Inc./Genetic Engineering News) Recently, the U.S. National Institutes of Health (NIH) and Food and Drug Administration (FDA) called for the eliminating involvement of the Recombinant DNA Advisory Committee (RAC) in human gene therapy experiments, marking the end of an era of federal government oversight. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 19, 2018 Category: Biology Source Type: news

Second Sight Medical wins $2m NIH grant for Orion sight implant
Second Sight Medical (NSDQ:EYES) said today that it won a grant of nearly $2 million from the National Institutes of Health to back the early feasibility trial of its Orion device for the visually impaired. The Sylmar, Calif.-based company said the $1.6 million grant is part of a five-year, $6.3 million package that’s slated to fund the trial, which began in January. The NIH grant will cover the enrollment and treatment of five patients with Orion, a visual cortical implant that links to an eyeglass-worn camera, Second Sight said. The device is designed to bypass the optic nerve by sending the camera’s images t...
Source: Mass Device - September 18, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Funding Roundup Optical/Ophthalmic Source Type: news

Researchers find adult stem cell characteristics in aggressive cancers from different tissues
UCLA researchers have discovered  genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how ag gressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers. The study, led by senior authors Owen Witte and Thomas Graeber, both of the  UCLA E...
Source: UCLA Newsroom: Health Sciences - September 18, 2018 Category: Universities & Medical Training Source Type: news

Researchers launch early-stage trial for nasal flu vaccine
Researchers at St. Louis University reported that an early-stage trial testing an experimental nasal flu vaccine in children and teens began enrolling participants this week. In the 50-person study, half of the participants will receive the investigational nasal vaccine and the other half will receive an inactive saline solution. All of the study’s participants are slated to receive an intramuscular injection of a quadrivalent seasonal flu vaccine three months following the initial dose of nasal vaccine or placebo. Get the full story at our sister site, Drug Delivery Business News. The post Researchers launch early-s...
Source: Mass Device - September 18, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Pharmaceuticals flugen National Institutes of Health (NIH) Source Type: news

An interview on consumer involvement in research with Simon Denegri, NIHR
For this year ’s Patients IncludedCochrane Colloquium, Richard Morley interviewed Simon Denegri, National Director for Patients, Carers and the Public, UK National Institute of Health Research. Simon talked about patient/consumer involvement in research, co-production, the role of researchers in meaningfully involving stakeholders, and what challenges he might set for Cochrane.Learn more about consumer involvement in CochraneTuesday, September 18, 2018 (Source: Cochrane News and Events)
Source: Cochrane News and Events - September 18, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

TGen participates in launch of NIH-supported Kids First Data Resource Portal
(The Translational Genomics Research Institute) TGen and the Pacific Pediatric Neuro-Oncology Consortium (PNOC) are participating in the launch of the Kids First Data Resource Portal, which is supported by the National Institutes of Health (NIH). The portal is designed to accelerate ways to better diagnosis, monitor and treat diverse types of pediatric diseases, including childhood cancers, by giving scientists and physicians an easy way to access large-scale genomic and clinical datasets. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2018 Category: International Medicine & Public Health Source Type: news

Penn researchers receive $18 million grant for Tobacco Center of Regulatory Science
(University of Pennsylvania School of Medicine) A new $18 million grant to Penn Medicine researchers will allow them to take aim at the effects of tobacco marketing. The U.S. Food and Drug Administration (FDA) and National Institutes of Health (NIH) have renewed their commitment to the Tobacco Centers of Regulatory Science (TCORS) program and awarded a second cohort (TCORS 2.0) of centers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 18, 2018 Category: International Medicine & Public Health Source Type: news

Fasting increases health and lifespan in male mice
Long periods of fasting between meals helped male mice live longer and healthier lives, regardless of the content of their diets. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 18, 2018 Category: Consumer Health News Source Type: news

Regrowing neurons across scarred spinal tissue
Researchers stimulated neurons to regrow across scarred spinal tissue in rodents. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 18, 2018 Category: Consumer Health News Source Type: news

Machine learning predicts risk of aneurysm
Researchers used machine learning to develop a method of predicting which people are at risk of developing an abdominal aneurysm. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 17, 2018 Category: Consumer Health News Source Type: news

Why Monell's latest NIH grant is leaving no bitter tastes
The Philadelphia-based Monell Center and Discovery BioMed Inc. of Birmingham, Ala., have received a $271,000 National Institutes of Health grant. The two are in an academic-commercial partnership using taste technology to improve human health. The funding, awarded through the Small Business Technology Transfer program at the NIH, will be used to support development of next-generation screening technologies to enable identification of bitter taste blockers. The project’s ultimate goal is to advance… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 17, 2018 Category: Biotechnology Authors: John George Source Type: news

Experimental nasal influenza vaccine tested in kids, teens
NIH-supported Phase 1 trial of potential broadly protective vaccine. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 17, 2018 Category: American Health Source Type: news

NIH study finds daily aspirin does not prolong healthy lifespan
In a 19,114-person trial supported by the National Institutes of Health, researchers found that daily low-dose aspirin did not prolong independent living in healthy older adults. Initial findings from the Aspree trial, which began in 2010, were published in The New England Journal of Medicine this week. The study involved participants who did not have dementia or a physical disability. Researchers followed the study’s participants for an average of 4.7 years to measure outcomes. Get the full story at our sister site, Drug Delivery Business News. The post NIH study finds daily aspirin does not prolong healthy lif...
Source: Mass Device - September 17, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Clinical Trials Featured Pharmaceuticals National Institute of Health Source Type: news

Gene variations linked to severity of Zika-related birth defects, small NIH study suggests
Highly affected children were likely to have a mother with natural variations in genes for a key enzyme. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 17, 2018 Category: American Health Source Type: news

NIH and Children ’s National partner to advance pediatric clinical research
Inaugural symposium highlights collaboration in allergic, immunologic and infectious disease research. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 17, 2018 Category: American Health Source Type: news

NIAID and Children's National partner to advance pediatric clinical research
(NIH/National Institute of Allergy and Infectious Diseases) The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and Children's National Health System, a pediatric academic medical center in Washington, D.C., have launched a clinical research partnership devoted to treating and preventing allergic, immunologic and infectious diseases in children. An inaugural symposium will take place at Children's National on Sept. 17, 2018, to highlight the partnership and discuss current and future directions for its research activities. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2018 Category: International Medicine & Public Health Source Type: news

Experimental nasal influenza vaccine tested in kids, teens
(NIH/National Institute of Allergy and Infectious Diseases) An early-stage clinical trial testing the safety and immune-stimulating ability of an experimental nasal influenza vaccine in healthy 9- to 17-year-old children and teens has begun enrolling participants at a Vaccine and Treatment Evaluation Unit (VTEU) site at Saint Louis University, St. Louis, Missouri. The VTEU is funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 17, 2018 Category: Infectious Diseases Source Type: news

CWRU receives NIH funding to investigate new imaging approach for peripheral vascular disease
(Case Western Reserve University) Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 17, 2018 Category: International Medicine & Public Health Source Type: news

UCSF receives $20 million to study new tobacco products
(University of California - San Francisco) UC San Francisco has been awarded a five-year, $20 million grant from the US Food and Drug Administration and the National Institutes of Health to study the impacts of new and emerging tobacco products, including e-cigarettes and heated tobacco products (HTPs), which heat tobacco without combustion. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 17, 2018 Category: International Medicine & Public Health Source Type: news

Daily low-dose aspirin found to have no effect on healthy life span in older people
(NIH/National Institute on Aging) In a clinical trial to determine the effects of daily low-dose aspirin in healthy older adults without previous cardiovascular events, aspirin did not prolong healthy, independent living free of dementia or physical disability. These findings from the ASPirin in Reducing Events in the Elderly (ASPREE) trial, partially supported by the National Institutes of Health, were published online on September 16, 2018 in three papers in The New England Journal of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 16, 2018 Category: International Medicine & Public Health Source Type: news

Daily low-dose aspirin found to have no effect on healthy life span in older people
Large NIH-funded study examined outcomes in United States and Australia (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 14, 2018 Category: American Health Source Type: news

Woods Hole Center for Oceans and Human Health receives five-year funding
(Woods Hole Oceanographic Institution) The National Science Foundation (NSF) and National Institute of Environmental Health Sciences (NIEHS), one of the National Institutes of Health, have announced that the Woods Hole Oceanographic Institution (WHOI) will receive funding to continue operating the Woods Hole Center for Oceans and Human Health (WHCOHH). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2018 Category: International Medicine & Public Health Source Type: news

Case Western Reserve's Dr. Lan Zhou receives $2M to study colorectal cancer development
(Case Western Reserve University) Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2018 Category: International Medicine & Public Health Source Type: news

UCLA-led team develops new system for tracking chemicals in the brain
UCLA and Columbia University researchers have developed a new method for tracking the activities of small molecules in the brain, including the neurotransmitters serotonin and dopamine.“Understanding the fundamentals of how neurotransmission occurs will help us understand not only how our brains work, but what’s going on in psychiatric disorders,” said Anne Andrews, the study’s lead author, a UCLA professor of psychiatry and chemistry.The research, which was published in the journal Science, is part of the BRAIN Initiative, a collaboration among government, private industry, nonprofits, and colleges...
Source: UCLA Newsroom: Health Sciences - September 13, 2018 Category: Universities & Medical Training Source Type: news

NIH launches initiative to accelerate genetic therapies to cure sickle cell disease
Effort will take advantage of the latest genetic discoveries and technological advances. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 13, 2018 Category: American Health Source Type: news

Neurons absorb and release water when firing, NIH study suggests
Findings in rat cell cultures could lead to new method for tracking communications throughout the brain. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 13, 2018 Category: American Health Source Type: news

Junior investigators successfully compete for extra NIH grants
(PLOS) More than half of early-career scientists who received their first research project (R01) grants from the National Institute of Allergy and Infectious Diseases (NIAID) are successful in obtaining subsequent funding from the National Institutes of Health (NIH), according to a study published September 12 in the open-access journal PLOS ONE by Patricia Haggerty and Matthew Fenton of NIAID, an NIH institute. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 13, 2018 Category: International Medicine & Public Health Source Type: news

Point-of-care sensors to detect manganese from single drop of blood
(University of Illinois at Chicago) A three-year, $1.8 million grant from the National Institutes of Health will enable researchers at the University of Illinois at Chicago to develop portable, easy-to-use sensors that can detect toxic metals in a single drop of blood. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - September 13, 2018 Category: Biology Source Type: news

Building a safer heart pump
(Penn State) Blood pumps are increasingly a bridge-to-transplant for patients with end-stage heart disease or heart failure, but blood clots and strokes can put patients in peril before they receive a donor heart. Now a four-year, $3 million grant from the National Institutes of Health may solve this problem and perhaps open the pumps' use for less-sick patients who could benefit from them. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2018 Category: International Medicine & Public Health Source Type: news

Duke University startup scores federal grant, plots hires
With a just-awarded $1.5 million grant from the National Institute of Health, a Durham startup working out of Biolabs NC hopes to make a difference. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 12, 2018 Category: Pharmaceuticals Authors: Lauren K. Ohnesorge Source Type: news

Health Tip: Recognizing a Learning Disorder
-- Learning a new subject may involve many mistakes. But when they are too frequent and long-lasting, they may be symptoms of a learning disorder, the National Institutes of Health says. A learning disability isn't a measure of how smart a child is.... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 12, 2018 Category: General Medicine Source Type: news

High blood sugar during pregnancy ups risk of mother ’s type 2 diabetes, child’s obesity
Researchers followed mothers and their children 10-14 years after birth. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 11, 2018 Category: American Health Source Type: news

High blood sugar during pregnancy increases your CHILD'S risk of type 2 diabetes in later life
A new follow-up study from the National Institutes of Health has found that untreated elevated blood glucose levels in pregnant women raises the risk of developing type 2 diabetes a decade later. (Source: the Mail online | Health)
Source: the Mail online | Health - September 11, 2018 Category: Consumer Health News Source Type: news

Wake Forest Baptist receives federal grants to study neurological disorders and stroke
(Wake Forest Baptist Medical Center) The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), has awarded Wake Forest Baptist Medical Center two five-year grants, each worth approximately $1.5 million, to participate in two nationwide clinical trial networks. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 11, 2018 Category: International Medicine & Public Health Source Type: news

Predicting response to immunotherapy
Studies show progress in learning to predict which patients are most likely to respond to certain cancer treatments known as immune checkpoint therapies. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 11, 2018 Category: Consumer Health News Source Type: news

Regenerating light-sensing eye cells in mice
Researchers restored some vision in mice with congenital blindness by changing supportive cells in the retina called M üller glia into light-sensing cells. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 11, 2018 Category: Consumer Health News Source Type: news

Device improves survival after sudden cardiac arrest
A device for supplying oxygen after sudden cardiac arrest outside of a hospital improved survival compared with a more common but invasive and difficult procedure. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 10, 2018 Category: Consumer Health News Source Type: news

NIDCR E-Newsletter: Fall 2018
Having trouble viewing this email? View it as a Web page. NIDCR's Fall 2018 E-Newsletter is now available. In this issue: NIDCR News NIH/HHS News Science Advances Funding Opportunities Funding Notices The National Institute of Dental and Craniofacial Research National Institutes of Health Bethesda, MD 20892-2190 301-496-4261 (Source: NIDCR Science News)
Source: NIDCR Science News - September 10, 2018 Category: Dentistry Source Type: news

Pittsburgh-based Opioid Research Center gets $7.2M grant
Rand Corp.'s Pittsburgh-based Opioid Policy Tools and Information Center received a $7.2 million grant from a subsidiary of the National Institutes of Health. The research center, dubbed OPTIC, will work on ways to determine the impact of opioid policies, why some work and some don't, and also develop a simulator that can determine effective methods and policies to stop the opioid crisis. OPTIC's director is Dr. Bradley D. Stein and the co-directors are Rand Senior Economist Rosalie Liccardo Pacula… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 10, 2018 Category: American Health Authors: Paul J. Gough Source Type: news

Early stage clinical trial of antimalarial drug begins
In 2016, an estimated 216 million new malaria cases and 445,000 deaths occurred. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 10, 2018 Category: American Health Source Type: news

Early-Stage Clinical Trial of Antimalarial Drug Begins
(NIH/National Institute of Allergy and Infectious Diseases) Enrollment has begun in a Phase 1 clinical trial to test the safety of a new investigational drug designed to treat malaria, as well as its effect on the human body. The first-in-human study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), and is being conducted at the Duke University School of Medicine in Durham, North Carolina. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 10, 2018 Category: Infectious Diseases Source Type: news