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The Long and Tortured History of Alpha-Synuclein and Parkinson ’s Disease
This study tracks the decades-long journey to harness alpha-synuclein as a treatment for Parkinson’s disease. Steven Zecola an activist who tracks Parkinson’s research and was on THCB last month discussing it, offers three key changes needed to overcome the underlying challenges. A Quick Start for Alpha-Synuclein R&D In the mid-1990’s, Parkinson’s patient advocacy groups had become impatient by the absence of any major therapeutic advances in the 25 years since L-dopa had been approved for Parkinson’s disease (PD). The Director of National Institute of Neurological Disorders and Stroke (NINDS) se...
Source: The Health Care Blog - March 29, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice Parkinson's Disease Steven Zecola Source Type: blogs

What Is the Microbiome?
Have you ever noticed a skin care product advertised as “microbiome friendly” and wondered what that meant? The microbiome is the collection of all the microbes—including bacteria, viruses, and fungi—that live in a specific environment, such as on the skin or in the digestive tract. Escherichia coli (E. coli) is a bacterial species commonly found in the human intestine. While some strains of E. coli cause foodborne illness, others are helpful members of the gut microbiome.Credit: Mark Ellisman and Thomas Deerinck, National Center for Microscopy and Imaging Research, University of California, San Diego. It’s ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - March 20, 2024 Category: Research Authors: Chrissa Chverchko Tags: Cells Common questions Microbes Microbiome Source Type: blogs

Four Steps to Success in Implementing AI Within Healthcare Organizations
The following is a guest article by Ben Cushing, Chief Architect of Health and Life Sciences at Red Hat Artificial intelligence (AI) is showing up in more healthcare contexts, from drug discovery to diagnostic imaging to robot-assisted surgery. But one area where AI can have a tremendous impact is in the reduction of provider burden. For instance, the Veterans Health Administration (VHA) is exploring automated, AI-assisted documentation of patient visits with clinicians. The system records the conversation between clinician and patient, and then automatically produces a clinical note. The AI system can apply accurate medic...
Source: EMR and HIPAA - March 19, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Ambulatory C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops LTPAC AI Implementation Artificial Intelligence Ben Cushing Healthcare AI Process Automation Source Type: blogs

Trial By Error: Professor Chris Ponting on the NIH ’ s Findings and the Latest on the Genome-Wide Association Study Update
By David Tuller, DrPH When the US National Institutes of Health released its lengthy ME/CFS study last month with much fanfare and publicity, the London-based Science Media Centre asked Professor Chris Ponting, among other experts, to provide comment. The study–“Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome”–was published by Nature Communications. It included in-depth findings … Trial By Error: Professor Chris Ponting on the NIH’s Findings and the Latest on the Genome-Wide Association Study Update Read More » (Source: virology blog)
Source: virology blog - March 18, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs

Home Health AI: Predicting Illness and Preventing Hospitalizations
The following is a guest article by Shveta Mangal, CEO at VitaWerks In today’s rapidly evolving healthcare environment, the concept of home as an “extension of care” is gaining traction, ushering in a new era of patient-centered support. Traditionally, healthcare was confined to clinical settings, but with advancements in technology, particularly artificial intelligence (AI) and machine learning, the paradigm is shifting. These cutting-edge technologies are now being harnessed to predict health issues before they escalate, revolutionizing home health care and paving the way for proactive interventions tha...
Source: EMR and HIPAA - March 5, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT Hospital - Health System Telemedicine and Remote Monitoring Healthcare at Home Home Health AI Home Health Care Home Healthcare Hospitalization Prevention Illness Prediction Source Type: blogs

Why Flight Emergency Medical Kits Need A Digital Health Upgrade
A few weeks ago a doctor used an Apple Watch to aid an elderly woman who suffered a medical emergency on a flight. NHS doctor Rashid Riaz, from Hereford, borrowed the device from a flight attendant to check the patient’s oxygen levels. “The Apple Watch helped me find out the patient had low oxygen saturation,” the medic explained. Later, he also called on all airlines to consider having emergency physician kits as standard, which would ideally include tools to take basic measurements, diabetic and blood pressure meters, and an oxygen saturation monitor. We all know that aircraft have some medical su...
Source: The Medical Futurist - February 27, 2024 Category: Information Technology Authors: berci.mesko Tags: Future of Medicine Health Sensors & Trackers portable diagnostics emergency medicine Healthcare technology flight medicine wearables Source Type: blogs

ARCADIA Trial on Atrial Cardiopathy and Stroke
In an earlier post on Embolic Stroke of Undetermined Source (ESUS), I had mentioned about ARCADIA trial (AtRial Cardiopathy and Antithrombotic Drugs In Prevention After Cryptogenic Stroke) which was testing whether there is role for apixaban compared to aspirin for prevention of recurrent stroke in ESUS. The trial was sponsored by the National Institutes of Health, United States of America and the results have been published in February 2024. ARCADIA trial showed that in patients with cryptogenic stroke and atrial cardiopathy, apixaban did not reduce the risk of recurrent stroke compared with low dose aspirin. The study wa...
Source: Cardiophile MD - February 19, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Funny How Your Past Can Come Back All In A Rush! A Good Reminder Of Times Past.
I noticed this a day or so ago. Colorful Mystery Solved: Scientists Discover Enzyme That Makes Urine Yellow Finding Could Illuminate Future Studies of Gut Health and Inflammatory Bowel Disease Researchers at the University of Maryland and National Institutes of Health have identified the enzyme responsible for giving urine a yellow hue, and it ’s more than a matter of idle curiosity or (Source: Australian Health Information Technology)
Source: Australian Health Information Technology - January 10, 2024 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs

Trial By Error: #MEAction ’ s Jaime Seltzer on Recent NIH Gathering
By David Tuller, DrPH Last Tuesday and Wednesday (December 12th and 13th), the US National Institutes of Health–and, specifically, the National Institute of Allergy and Infectious Diseases–held a two-day meeting called “Advancing ME/CFS Research: Identifying Targets for Intervention and Learning from Long COVID.” In 2019, I’d physically attended a similar NIH gathering; this time, I … Trial By Error: #MEAction’s Jaime Seltzer on Recent NIH Gathering Read More » (Source: virology blog)
Source: virology blog - December 18, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized NIH Source Type: blogs

What Is the Immune System?
A computer-generated image of the rotavirus, a virus that commonly causes illness in children through inflammation of the stomach and intestines. Credit: Bridget Carragher, The Scripps Research Institute, La Jolla, California. What do antibodies, mucus, and stomach acid have in common? They’re all parts of the immune system! The immune system is a trained army of cells, tissues, and organs that work together to block, detect, and eliminate harmful insults to your body. It can protect you from invaders like bacteria, viruses, fungi, and parasites. Innate and Adaptive The immune system is often thought of as two...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 11, 2023 Category: Research Authors: Chrissa Chverchko Tags: Cells Common questions Immunology Miniseries Infectious Diseases Microbes Source Type: blogs

The State Of CRISPR Clinical Trials And Their Future Potentials
CRISPR, short for “Clustered Regularly Interspaced Short Palindromic Repeats” – and more specifically CRISPR–Cas9 – relates to a gene-editing method that gained popularity in the past decade; and not for trivial reasons. Being the most efficient and accurate method to edit a cell’s genome, CRISPR holds potentials that range from treating conditions such as HIV to finding new drug targets. While such potentials are real and are being actively investigated, you might be curious about more practical examples of CRISPR applications. By taking the US Clinical Trials registry as an example, we consider lis...
Source: The Medical Futurist - December 7, 2023 Category: Information Technology Authors: Pranavsingh Dhunnoo Tags: TMF CRISPR therapy clinical trials gene editing Source Type: blogs

Spotlighting SEPA for National STEM Day
The NIGMS Science Education Partnership Award (SEPA) program provides opportunities for pre-K-12 students from underserved communities to access STEM educational resources. SEPA grants support innovative, research-based, science education programs, furthering NIGMS’ mission to ensure a strong and diverse biomedical research workforce. SEPA projects generate resources that are mapped to state and national teaching standards for STEM and are rigorously evaluated for effectiveness; most are also available at no cost. These resources include mobile laboratories, interactive health exhibits in museums and science centers, edu...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 8, 2023 Category: Research Authors: Chrissa Chverchko Tags: STEM Education Research Roundup SEPA Training Source Type: blogs

What is the physician ’ s role in the food is medicine movement?
In the early 1990s, complementary and alternative medicine (CAM) began its rise with the development of the National Institutes of Health’s CAM center. However, scientists and clinicians struggled with the decision of whether or not to allow individuals access to information on these CAM approaches. I was part of that discourse as I was invited Read more… What is the physician’s role in the food is medicine movement? originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 4, 2023 Category: General Medicine Authors: Deb Kennedy, PhD Tags: Conditions Nutrition Source Type: blogs

Trial By Error: Interview with Journalist Betsy Ladyzhets about NIH ’ s Flawed $1.2 Billion RECOVER Program for Long Covid
By David Tuller, DrPH Betsy Ladyzhets is an independent health, science and data journalist who has been covering the coronavirus pandemic, including long Covid. While serving as a journalism fellow at MuckRock, she co-wrote an investigative report for STAT, a well-known health and medical news site, about the US National Institutes of Health’s problem-plagued $1.2 … Trial By Error: Interview with Journalist Betsy Ladyzhets about NIH’s Flawed $1.2 Billion RECOVER Program for Long Covid Read More » (Source: virology blog)
Source: virology blog - September 12, 2023 Category: Virology Authors: David Tuller Tags: Uncategorized Ladyzhets NIH RECOVER program STAT Source Type: blogs

Up Your Game With NIH Kahoot! Quizzes
NIH is now a premium partner with Kahoot! Credit: NIGMS. We’re excited to announce our new partnership with Kahoot! Although we aren’t new Kahoot! gamers, we’ve recently partnered with them to provide you quizzes from across the National Institutes of Health (NIH) in a single place. “Reaching young people to teach them about biomedical science and inspire them to pursue careers in science is critically important to ensuring a diverse and vibrant biomedical research enterprise,” says NIGMS Director Jon Lorsch, Ph.D. “Our partnership with Kahoot! expands NIH’s STEM offerings, providing educators with free, in...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - August 23, 2023 Category: Research Authors: Chrissa Chverchko Tags: STEM Education Source Type: blogs