National Institutes of Health (NIH) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

NIH boosts pay for postdocs and graduate students
The U.S. National Institutes of Health (NIH) announced pay increases today for early-career scientists who are recipients of its Ruth L. Kirschstein National Research Service Awards (NRSAs), after an NIH advisory group recommended raises in December 2023 . Postdocs will now be paid at least $61,008, an increase of $4500 over their current minimum salary level—though still below the advisory group’s recommendation of $70,000. Graduate students will receive a $1000 raise, bringing their minimum to $28,224. NIH also announced a $500 increase in child care subsidies for early-career researchers who are parents. ...
Source: Science of Aging Knowledge Environment - April 23, 2024 Category: Geriatrics Source Type: research

Brain-Derived Exosomal CircRNAs in Plasma Serve as Diagnostic Biomarkers for Acute Ischemic Stroke
AbstractAcute ischemic stroke (AIS), commonly known as stroke, is a debilitating condition characterized by the interruption of blood flow to the brain, resulting in tissue damage and neurological deficits. Early diagnosis is crucial for effective intervention and management, as timely treatment can significantly improve patient outcomes. Therefore, novel methods for the early diagnosis of AIS are urgently needed. Several studies have shown that bioactive molecules contained in extracellular vesicles, especially circRNAs, could be ideal markers for the diagnosis of many diseases. However, studies on the effects of exosomes...
Source: Journal of NeuroImmune Pharmacology - April 22, 2024 Category: Drugs & Pharmacology Source Type: research

Genomic characterization of human respiratory syncytial virus circulating in Islamabad, Pakistan, during an outbreak in 2022-2023
In this study, conducted at the National Institute of Health, Islamabad, during an outbreak of human respiratory syncytial virus (hRSV) from December 2022 to January 2023, the first whole-genome sequences of hRSV isolates from Islamabad, Pakistan, were determined. Out of 10 positive samples, five were sequenced, revealing the presence of two genotypes: RSV-A (GA2.3.5, ON1 strain) and RSV-B (GB5.0.5.a, BA-10 strain). A rare non-synonymous substitution (E232G) in G the protein and N276S in the F protein were found in RSV-A. In RSV-B, the unique mutations K191R, Q209R, and I206M were found in the F protein. These mutations co...
Source: Archives of Virology - April 22, 2024 Category: Virology Source Type: research

Sleep and circadian biomarkers of postoperative delirium (SLEEP-POD): protocol for a prospective and observational cohort study
This study is approved by the IRB at MGH, Boston, and it is registered with the US National Institutes of Health on ClinicalTrials.gov (NCT06052397). Plans for dissemination include conference presentations at a variety of scientific institutions. Results from this study are intended to be published in peer-reviewed journals. Relevant updates will be made available on ClinicalTrials.gov. Trial registration number NCT06052397. (Source: BMJ Open)
Source: BMJ Open - April 19, 2024 Category: General Medicine Authors: Sugg, E., Gleeson, E., Baker, S. N., Li, P., Gao, C., Mueller, A., Deng, H., Shen, S., Franco-Garcia, E., Saxena, R., Musiek, E. S., Akeju, O., Xie, Z., Hu, K., Gao, L. Tags: Open access, Anaesthesia Source Type: research

Anonymizing research funding applications could reduce ‘prestige privilege’
For research funders seeking to minimize bias in their selection process, removing applicants’ institutional affiliations from their submissions could help address a common disparity: disproportionate funding going to those at the most prestigious places. That’s the finding from researchers at the Arnold and Mabel Beckman Foundation, who reported last month in eLife that anonymized applications partially reduced the effects of reputational bias and evened the playing field for early-career faculty at lesser known institutions applying for their Beckman Young Investigator (BYI) awards. T...
Source: Science of Aging Knowledge Environment - April 18, 2024 Category: Geriatrics Source Type: research

Listening Sessions to Shape the Innovative NIH ComPASS Common Fund Program to Advance Health Equity
Am J Public Health. 2024 Apr 18:e1-e5. doi: 10.2105/AJPH.2024.307656. Online ahead of print.ABSTRACTThe National Institutes of Health (NIH) recognized the need for a research program to address the underlying structural factors that impact health. To inform the development of the NIH Common Fund Community Partnerships to Advance Science for Society (ComPASS) Program, NIH obtained input through community listening sessions. Through its design, ComPASS recognizes the essential role of community organizations as the lead in addressing persistent structural and social challenges to accelerate progress toward advancing health e...
Source: American Journal of Public Health - April 18, 2024 Category: International Medicine & Public Health Authors: Alison G M Brown Danyelle Winchester Shalanda A Bynum Sara M Amolegbe Yvonne O Ferguson Minnjuan Flournoy Floyd Collene Lawhorn Jimmy T Le Jacqueline Lloyd April Y Oh Nadra Tyus Damiya E Whitaker Cheryl Anne Boyce Source Type: research

Listening Sessions to Shape the Innovative NIH ComPASS Common Fund Program to Advance Health Equity
Am J Public Health. 2024 Apr 18:e1-e5. doi: 10.2105/AJPH.2024.307656. Online ahead of print.ABSTRACTThe National Institutes of Health (NIH) recognized the need for a research program to address the underlying structural factors that impact health. To inform the development of the NIH Common Fund Community Partnerships to Advance Science for Society (ComPASS) Program, NIH obtained input through community listening sessions. Through its design, ComPASS recognizes the essential role of community organizations as the lead in addressing persistent structural and social challenges to accelerate progress toward advancing health e...
Source: Am J Public Health - April 18, 2024 Category: International Medicine & Public Health Authors: Alison G M Brown Danyelle Winchester Shalanda A Bynum Sara M Amolegbe Yvonne O Ferguson Minnjuan Flournoy Floyd Collene Lawhorn Jimmy T Le Jacqueline Lloyd April Y Oh Nadra Tyus Damiya E Whitaker Cheryl Anne Boyce Source Type: research

Historical technology transfer activities and productivity of NIDLRR grantees
Assist Technol. 2024 Apr 17:1-13. doi: 10.1080/10400435.2024.2324051. Online ahead of print.ABSTRACTThis paper analyzes the technology-related outputs from The National Institute of Disability, Independent Living, and Rehabilitation Research (NIDILRR). We seek to answer the questions: What are the types and frequency of assistive technology (AT) technology transfer (ATTT) outputs from NIDILRR grants? How does NIDILRR's ATTT generation compare to other granting organizations? What types of ATTT outputs occur, how, and what is the relative productivity of the most frequently funded universities and small businesses performin...
Source: Assistive Technology - April 17, 2024 Category: Rehabilitation Authors: Erin Higgins Michelle Zorrilla Megan D'Innocenzo Mary R Goldberg Susan K Cohen Nancy Augustine Julie Faieta Kathleen Murphy Jonathan L Pearlman Source Type: research

Superficial Temporal Artery-to-Middle Cerebral Artery Bypass in Ischemic Stroke With Blood Pressure-Dependent Symptoms
In this report, we discuss how EC-IC bypass turned out to be beneficial for a patient presenting with blood pressure-dependent severe aphasia and right hemiparesis due to middle cerebral artery (MCA) occlusion that failed thrombectomy. CT perfusion (CTP) scan at admission demonstrated a persistent volume of delayed perfusion without core infarct. Following the superficial temporal artery-to-middle cerebral artery (STA-MCA) bypass, the patient's National Institute of Health Stroke Scale (NIHSS) score improved from 12 to 1. Ischemic penumbra, as seen on CTP imaging, also improved after the STA-MCA bypass. Our case suggests t...
Source: Atherosclerosis - April 15, 2024 Category: Cardiology Authors: Brendan Huang Calvin Huang Khaled Alok Alex Y Chen Source Type: research

An algorithm for the National Institute of Health Stroke Scale assessment: a multicenter, two-arm and cluster randomized study
The NIH Stroke Scale (NIHSS) is a validated tool for assessing stroke severity, increasingly used by general practitioners in telemedicine services. Mobile apps may enhance its reliability. We aim to validate a digital platform (SPOKES) for NIHSS assessment in telemedicine and healthcare settings. (Source: Journal of Stroke and Cerebrovascular Diseases)
Source: Journal of Stroke and Cerebrovascular Diseases - April 15, 2024 Category: Neurology Authors: Joao Brainer Clares de Andrade, Evelyn de Paula Pacheco, Millene Rodrigues Camilo, Carlos Eduardo Lenis Rodriguez, Paula Sanchez Nascimento, Nath ália Souza de Oliveira, Thiago S Carneiro, Renato Andre Castro de Oliveira, Gisele Sampaio Silva Source Type: research

SARS-CoV-2 and influenza virus coinfections in the Tuscan population during the 2021/2022 influenza season
The 2021/2022 influenza season was not characterised by a well-defined incidence peak. As reported by the Italian National Institute of Health, a high value of incidence of influenza cases was recorded in week 13, but it was still lower than in other influenza seasons. This abnormal circulation was probably due to relaxation of the COVID-19 pandemic restriction measures, which greatly reduced the circulation of respiratory-transmitted viruses, including human respiratory syncytial virus (HRSV). The symptoms of SARS-CoV-2 and influenza are quite similar, sharing the human-to-human transmission route via respiratory droplets...
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Ilaria Manini, Giovanna Milano, Serena Marchi, Ilaria Vicenti, Camilla Biba, Lia Fiaschi, Claudia Maria Trombetta, Giacomo Lazzeri, Emanuele Montomoli Source Type: research

An improvement method for pancreas CT segmentation using superpixel-based active contour
Phys Med Biol. 2024 Apr 12. doi: 10.1088/1361-6560/ad3e5c. Online ahead of print.ABSTRACTPancreas is one of the most challenging organs for CT image automatic segmentation due to its complex shapes and fuzzy edges. It is simple and universal to use the traditional segmentation method as a post-processor of deep learning method for segmentation accuracy improvement. As the most suitable traditional segmentation method for pancreatic segmentation, the active contour model(ACM), still suffers from the problems of weak boundary leakage and slow contour evolution speed. Therefore, a convenient post-processor for any deep learni...
Source: Physics in Medicine and Biology - April 12, 2024 Category: Physics Authors: Huayu Gao Jing Li Nanyan Shen Liang Liu Ying Yang Peng Hu Wei Lu Source Type: research

An improvement method for pancreas CT segmentation using superpixel-based active contour
Phys Med Biol. 2024 Apr 12. doi: 10.1088/1361-6560/ad3e5c. Online ahead of print.ABSTRACTPancreas is one of the most challenging organs for CT image automatic segmentation due to its complex shapes and fuzzy edges. It is simple and universal to use the traditional segmentation method as a post-processor of deep learning method for segmentation accuracy improvement. As the most suitable traditional segmentation method for pancreatic segmentation, the active contour model(ACM), still suffers from the problems of weak boundary leakage and slow contour evolution speed. Therefore, a convenient post-processor for any deep learni...
Source: Health Physics - April 12, 2024 Category: Physics Authors: Huayu Gao Jing Li Nanyan Shen Liang Liu Ying Yang Peng Hu Wei Lu Source Type: research