Blindness and neurological sequelae following carbon monoxide poisoning: effective treatment with hyperbaric oxygen - Cardoso PC, La Fuente A, Subbotina N, Cargnel EG.
We present two patients who developed visual deterioration due to carbon monoxide poisoning. They were treated with hyperbaric oxygen and recovered not only their vision but also they improved neurological signs and symptoms. We believe that implementation... (Source: SafetyLit)
Source: SafetyLit - September 16, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

New data show Roche ’s ENSPRYNG (satralizumab) significantly reduces severity and risk of relapse in neuromyelitis optica spectrum disorder (NMOSD)
Basel, 10 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new ENSPRYNG ® (satralizumab) data on reducing relapse severity in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare disease of the central nervous system. These data are being presented at MSVirtual2020, the 8th joint ACTRIMS-ECTRIMS meeting, in addition to longer-term efficacy data supporting the continued effect of ENSPRYNG on reducing the risk of NMOSD relapse, as well as its favourable benefit:risk profile.“The data for ENSPRYNG at MSVirtual2020 are promising and suggest it significantly reduces relapse severity ...
Source: Roche Investor Update - September 10, 2020 Category: Pharmaceuticals Source Type: news

New data show Roche ’s ENSPRYNG (satralizumab) significantly reduces severity and risk of relapse in neuromyelitis optica spectrum disorder (NMOSD)
Basel, 10 September 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new ENSPRYNG ® (satralizumab) data on reducing relapse severity in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare disease of the central nervous system. These data are being presented at MSVirtual2020, the 8th joint ACTRIMS-ECTRIMS meeting, in addition to longer-term efficacy data supporting the continued effect of ENSPRYNG on reducing the risk of NMOSD relapse, as well as its favourable benefit:risk profile.“The data for ENSPRYNG at MSVirtual2020 are promising and suggest it significantly reduces relapse severity ...
Source: Roche Media News - September 10, 2020 Category: Pharmaceuticals Source Type: news

Case report: projectile into right frontal lobe from a nail gun - Patchana T, Taka TM, Ghanchi H, Wiginton J, Wacker M.
We present a case of a nail gun injury penetrating the right maxillary sinus and frontal lobe with complaints of headache and right eye blindness. After surgical removal and treatment, there were no neurological deficits aside from the persistence of right... (Source: SafetyLit)
Source: SafetyLit - September 5, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

My face blindness is embarrassing – but it tells me a lot about other people
I grew up thinking I just didn ’t fit it. Now, I immediately tell people I can’t recognise faces – and their response is a good measure of kindness versus egoSunday morning. I walk down to the beach with the dog straining at her lead. I ’m already on high alert. It’s the moment in the week when people are most likely to be wandering along the seafront, feeling chatty. I’m mentally priming myself, sorting through the categories I might encounter: parents from the schoolyard (hopefully with their children), people I’ve worked with (increasingly hopeless), neighbours from the surround...
Source: Guardian Unlimited Science - August 30, 2020 Category: Science Authors: Katherine May Tags: Life and style Psychology Science Health & wellbeing Source Type: news

IrisVision and Seva Foundation work to treat vision impairment; Iron Bow Technologies integrates with ViiMed; and more digital health deals
In a partnership announced this week, IrisVision and Seva Foundation plan to develop new technology to treat vision impairment and prevent blindness in underserved regions of the globe. Seva has agreed to provide IrisVision with a $200,000 grant to create the technology. (Source: mobihealthnews)
Source: mobihealthnews - August 27, 2020 Category: Information Technology Source Type: news

Causes of childhood blindness and visual impairment in Ouagadougou: About 398 cases - Ahnoux-Zabsonre A, Meda R, Diallo JW, Djiguimde WP, Sanou J, Meda-Hien G, Sankara P, Diomand é A.
INTRODUCTION: Childhood blindness is a public health problem in developing countries. The goal of this study was to focus on the epidemiological and clinical patterns of moderate to severe, uni- or bilateral childhood blindness and severe visual impairment... (Source: SafetyLit)
Source: SafetyLit - August 26, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Remodeling vasculature to avoid blindness
(Source: ScienceNOW)
Source: ScienceNOW - August 20, 2020 Category: Science Authors: Podrez, E. A., Byzova, T. V. Tags: Medicine, Diseases perspective Source Type: news

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy
In developed countries, the leading causes of blindness such as diabetic retinopathy are characterized by disorganized vasculature that can become fibrotic. Although many such pathological vessels often naturally regress and spare sight-threatening complications, the underlying mechanisms remain unknown. Here, we used orthogonal approaches in human patients with proliferative diabetic retinopathy and a mouse model of ischemic retinopathies to identify an unconventional role for neutrophils in vascular remodeling during late-stage sterile inflammation. Senescent vasculature released a secretome that attracted neutrophils an...
Source: ScienceNOW - August 20, 2020 Category: Science Authors: Binet, F., Cagnone, G., Crespo-Garcia, S., Hata, M., Neault, M., Dejda, A., Wilson, A. M., Buscarlet, M., Mawambo, G. T., Howard, J. P., Diaz-Marin, R., Parinot, C., Guber, V., Pilon, F., Juneau, R., Laflamme, R., Sawchyn, C., Boulay, K., Leclerc, S., Abu Tags: Cell Biology, Medicine, Diseases, Online Only r-articles Source Type: news

Ocular injuries and blindness caused by crowd control measures in civil protests - Lum C, Schallhorn J, Lum F, Ramanathan S, Oatts J, de Alba Campomanes AG, Seitzman G.
Thirty cases of ocular injuries during civil protests were identified, with 27% suffering a ruptured globe, 23% with an orbital fracture, 20% with a resultant macular hole, and 33% with permanent blindness in the involved eye. Language: en... (Source: SafetyLit)
Source: SafetyLit - August 15, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Former Johnson & Johnson exec joins CorneaGen board
CorneaGen announced Thursday that Tom Frinzi, formerly worldwide president of Johnson& Johnson Vision, joined its board of directors. Seattle-based CorneaGen focuses on developing technologies to cure corneal blindness by 2040 and provides donor tissues for cornea transplants. Frinzi, with more than 35 years of experience in ophthalmology, will lead CorneaGen’s board as executive chair, replacing William Link, who will remai n on the board. “Tom’s deep experience in bringing ophthalmology… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - August 14, 2020 Category: Pharmaceuticals Authors: Megan Campbell Source Type: news

Heavy class A drug use linked to heightened risk of sight loss in US military
(BMJ) Heavy use of class A drugs, such as heroin, methamphetamine, or cocaine is linked to a heightened risk of partial or total blindness among US military personnel, finds research published online in the journal BMJ Military Health. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 13, 2020 Category: International Medicine & Public Health Source Type: news

Blindness breakthrough as monthly jabs first to half leading cause of sight loss
MONTHLY jabs of protein can halt the progression of a leading cause of sight loss, scientists have revealed. (Source: Daily Express - Health)
Source: Daily Express - Health - August 2, 2020 Category: Consumer Health News Source Type: news

FDA Broadens Alert on Methanol Hand Sanitizers
Deaths, blindness tied to toxic ingredient found in these sanitizers ... En espa ñol | The U.S. Food and Drug Administration (FDA) is warning consumers to stop using 94 hand sanitizer products from ... (Source: AARP.org News)
Source: AARP.org News - August 2, 2020 Category: American Health Source Type: news

Researchers discover stem cells in optic nerve that preserve vision
(University of Maryland School of Medicine) Researchers at the University of Maryland School of Medicine (UMSOM) have for the first time identified stem cells in the region of the optic nerve, which transmits signals from the eye to the brain. The finding, published this week in the journal Proceedings of the National Academy of Sciences (PNAS), presents a new theory on why the most common form of glaucoma may develop and provides potential to treat a leading cause of blindness. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 30, 2020 Category: International Medicine & Public Health Source Type: news

Durham biotech uses new funding to acquire gene therapy for eye disease
A Hatteras backed early stage life science company has used its new funding to acquire the exclusive rights to a gene therapy platform targeting eye disease. On Wednesday, Durham-based Atsena Therapeutics announced that it has acquired the exclusive rights to a gene therapy from French pharma giant Sanofi. The therapy targets GUCY2D-associated Leber congenital amaurosis (LCA1) – a genetic eye disease that affects the retina and is a leading cause of blindness in children. The acquisition follows… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - July 29, 2020 Category: Pharmaceuticals Authors: Seth Thomas Gulledge Source Type: news

FDA Expands Alert on Methanol Hand Sanitizers
Deaths, blindness tied to toxic ingredient found in imported sanitizers ... En espa ñol | The U.S. Food and Drug Administration (FDA) is warning consumers to stop using 86 hand sanitizer products fr... (Source: AARP.org News)
Source: AARP.org News - July 29, 2020 Category: American Health Source Type: news

FDA Cites Increased Reports of Injury After Americans Use —and Sometimes Ingest—Unauthorized Hand Sanitizers
(WASHINGTON) — U.S. health officials are warning Americans again to avoid a growing list of imported hand sanitizers that may be contaminated with the toxic chemical methanol. The Food and Drug Administration said Monday there have been increasing reports of injury due to people using— sometimes ingesting—the unauthorized sanitizers, which can lead to blindness, heart problems and death. The active ingredient that kills germs in legitimate sanitizers is ethyl alcohol, which is consumable. But some Mexican companies have been replacing it with poisonous methanol, or wood alcohol, which is used in antifreez...
Source: TIME: Health - July 28, 2020 Category: Consumer Health News Authors: Associated Press Tags: Uncategorized News Desk Public Health wire Source Type: news

Federal Regulators Recall 77 Hand Sanitizers Due To Potentially Deadly Levels Of Methanol
Substantial methanol exposure can result in nausea, vomiting, headache, blurred vision, permanent blindness, seizures, coma or permanent damage to the nervous system. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 24, 2020 Category: Pharmaceuticals Authors: Tommy Beer, Forbes Staff Tags: Business /business Healthcare /healthcare Science /science Breaking breaking-news Coronavirus SportsMoney Source Type: news

Real Clean Distribuciones SA de CV Issues Voluntary Nationwide Recall of Four Hand Sanitizer Due to Potential Presence of Undeclared Methanol (Wood Alcohol)
La Loma, Tlalnepantla, Mexico, Real Clean Distribuciones SA de CV is voluntarily recalling all lots it manufactured within expiry of the following brand names of hand sanitizers: Substantial methanol exposure could result in nausea, vomiting, headache, blurred vision, permanent blindness, seizures, (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 24, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Media News - July 22, 2020 Category: Pharmaceuticals Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Investor Update - July 22, 2020 Category: Pharmaceuticals Source Type: news

Cinnamon May Slow Progression To Type 2 Diabetes, Boston Study Finds
(CNN) — Cinnamon may improve blood sugar control in people with a condition known as prediabetes and may slow the progression to type 2 diabetes, according to a new pilot study of 51 people with elevated blood sugars. “We are looking for safe, durable and cost-effective approaches to reduce the progression from prediabetes to type 2 diabetes,” said study author Dr. Giulio Romeo, a staff physician at Boston’s Joslin Diabetes Center and the division of endocrinology at Beth Israel Deaconess Medical Center. The study published Tuesday in the Journal of the Endocrine Society. “Our 12-week study sh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 21, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated CBSN Boston Cinnamon CNN Diabetes Source Type: news

Interim Six-Month Data of RPGR Gene Therapy Shows Significant Vision Improvement in Patients Living with X-Linked Retinitis Pigmentosa
Click to Access Audio Press ReleaseRARITAN, NJ, July 17, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today six-month data from the ongoing Phase 1/2 trial (NCT03252847) of its investigational gene therapy for the treatment of inherited retinal disease X-linked retinitis pigmentosa (XLRP). The interim data showed that low and intermediate doses of the investigational adeno-associated virus retinitis pigmentosa GTPase regulator (AAV-RPGR) were generally well-tolerated and indicated significant improvement in vision. Initial data on the novel AAV-RPGR asset, jointly developed with Meir...
Source: Johnson and Johnson - July 17, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Nearly 60 hand sanitizers potentially toxic, FDA warns
Disinfectant products that contain wood alcohol are linked to blindness and fatalities, federal safety watchdog says. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 14, 2020 Category: Consumer Health News Source Type: news

Dissolving eye implant the size of a grain of sand could help save the sight of glaucoma patients 
An eye implant measuring just 0.2mm by 1mm could revolutionise the treatment of glaucoma, a condition that affects 500,000 Britons and is a leading cause of blindness. (Source: the Mail online | Health)
Source: the Mail online | Health - July 13, 2020 Category: Consumer Health News Source Type: news

Do I Need A Face Shield For My Job? Dr. Mallika Marshall Answers Your Coronavirus Questions
BOSTON (CBS) — Dr. Mallika Marshall is answering your coronavirus-related medical questions. If you have a question for Dr. Mallika, email her or message her on Facebook or Twitter. Dr. Mallika is offering her best advice, but as always consult your personal doctor before making any decisions about your personal health. “I found out I have been using hand sanitizer that has been recalled. I have thrown it away. How worried should I be?” -Eileen The FDA has warned that dozens of hand sanitizers that may contain a toxic substance called methanol. Substantial exposure to this ch...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 13, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Syndicated CBSN Boston Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news

Nearly 60 hand sanitizers potentially toxic, FDA warns
Disinfectant products that contain wood alcohol are linked to blindness and fatalities, federal safety watchdog says. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - July 13, 2020 Category: Consumer Health News Source Type: news

Epidemiology and prognostic factors of open globe injuries in a Tunisian pediatric population - Malek I, Sayadi J, Zerei N, Mekni M, El Amri K, Zgolli H, Chebbi A, Nacef L.
INTRODUCTION: Childhood ocular trauma is a preventable cause of visual impairment and blindness worldwide. The purpose of our study was to determine demographic, etiologic, and clinical characteristics, visual outcome, and factors affecting visual prognosi... (Source: SafetyLit)
Source: SafetyLit - July 11, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

More than meets the eye
(Harvard Medical School) New findings reframe the traditional view of face blindness as a disorder arising strictly from deficits in visual perception of facial features. Findings suggest prosopagnosia may be a more complex disorder rooted in multiple deficits. Findings can help inform the design of tools to improve face recognition in those with the condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 10, 2020 Category: International Medicine & Public Health Source Type: news

Technology Bridges the Gap to Better Sight
More than 6 million Americans have vision problems that cannot be corrected by glasses or contact lenses. Companies like IrisVision are creating headsets to help them see better. (Source: NYT Health)
Source: NYT Health - July 7, 2020 Category: Consumer Health News Authors: Janet Morrissey Tags: Eyes and Eyesight Disabilities Headphones and Headsets Blindness Glaucoma Macular Degeneration Virtual Reality (Computers) IrisVision Global Inc AI July August 2020 Source Type: news

FDA Warns Of 5 More Potentially Toxic Hand Sanitizers
BOSTON (CBS) – Five more brands of hand sanitizer have tested positive for a toxic chemical. The FDA says they all contain methanol, which can be dangerous when ingested or absorbed through the skin. “The agency is aware of adults and children ingesting hand sanitizer products contaminated with methanol that has led to recent adverse events including blindness, hospitalizations and death,” the FDA said in a statement. Last month, the agency listed nine brands to avoid because they contain methanol. Here are the five brands added to the FDA list: Grupo Insoma’s Hand Sanitizer Gel Unscented 70% Alcoh...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 7, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Consumer Covid-19 Boston, MA Featured Health Healthcare Status Syndicated CBSN Boston Syndicated Local FDA Hand Sanitizer Source Type: news

A Safer 4th Is One Without Backyard Fireworks
WEDNESDAY, July 1, 2020 -- If you plan to celebrate Independence Day, you might want to reconsider setting off fireworks, Prevent Blindness suggests. There are other, safer ways to mark the United States of America's birthday, according to the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 1, 2020 Category: General Medicine Source Type: news

Blindness
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 30, 2020 Category: General Medicine Source Type: news

New eye drops may prevent a common cause of blindness
(Columbia University Irving Medical Center) New eye drops could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults, a study by Columbia University researchers has found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

FDA Warns These 9 Hand Sanitizers Could Be Toxic
The U.S. Food and Drug Administration (FDA) is warning consumers should avoid using any hand sanitizers from a particular manufacturer because they could contain a toxic ingredient. The FDA says the products, manufactured by Eskbiochem SA de CV in Mexico, could contain methanol, which can be toxic when ingested or absorbed through the skin. In a statement on Friday, the FDA said it had identified the following Eskbiochem hand sanitizers: All-Clean Hand Sanitizer (NDC: 74589-002-01) Esk Biochem Hand Sanitizer (NDC: 74589-007-01) CleanCare NoGerm Advanced Hand Sanitizer 75% Alcohol (NDC: 74589-008-04) Lavar 70 Gel Hand Sani...
Source: TIME: Health - June 23, 2020 Category: Consumer Health News Authors: Madeleine Carlisle Tags: Uncategorized COVID-19 News Desk Source Type: news

FDA: Don ’t Use These 9 Hand Sanitizers Due To Toxic Ingredient
This ingredient could cause nausea, vomiting, headaches, seizures, blindness, coma, permanent damage to your nervous system or death. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - June 23, 2020 Category: Pharmaceuticals Authors: Bruce Y. Lee, Senior Contributor Tags: Healthcare /healthcare Innovation /innovation Business /business Retail /retail Editors' Pick editors-pick Coronavirus pharma Source Type: news

RIT earns NIH grant to use virtual reality to help stroke patients regain lost vision
(Rochester Institute of Technology) Scientists from Rochester Institute of Technology and the University of Rochester aim to use virtual reality to help restore vision for people with stroke-induced blindness. The team of researchers led by Gabriel Diaz, associate professor at RIT's Chester F. Carlson Center for Imaging Science, received a grant from the National Institutes of Health to develop a method they believe could revolutionize rehabilitation for patients with cortically induced blindness. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 16, 2020 Category: International Medicine & Public Health Source Type: news

A vitamin A analog may help treat diabetic retinopathy
(Elsevier) Diabetic retinopathy is a common complication of diabetes and a leading cause of blindness among the working-age population. A new study in The American Journal of Pathology reports that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a light sensitive element of the retina. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 11, 2020 Category: International Medicine & Public Health Source Type: news

Eye Experts Call for Ban on Police Use of Rubber Bullets
TUESDAY, June 9, 2020 -- Rubber bullets can cause severe eye injuries, blindness and even death, and they shouldn't be used against protesters, claims a petition signed by almost 400 U.S. eye doctors. The petition was first launched by... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 9, 2020 Category: General Medicine Source Type: news

For the Deaf, Social Distancing Can Mean Social Isolation
Masks, enforced social distance and other public health measures intended to slow the spread of the coronavirus pose unique challenges to the 37 million American adults with impaired hearing. (Source: NYT Health)
Source: NYT Health - June 4, 2020 Category: Consumer Health News Authors: Derrick Bryson Taylor Tags: Deafness Disabilities Masks Coronavirus (2019-nCoV) Blindness Sign Language Protective Clothing and Gear Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Investor Update - May 27, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Media News - May 27, 2020 Category: Pharmaceuticals Source Type: news

Essential key to hearing sensitivity discovered
(University of Virginia Health System) New research is shedding light on the biological architecture that lets us hear -- and on a genetic disorder that causes both deafness and blindness. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - May 26, 2020 Category: Biology Source Type: news

Activation in individuals with vision loss - Morse AR, Seiple W.
Vision loss and blindness are significant causes of disability. Patient activation has been previously unstudied in individuals with vision loss. Among our 146 participants, visual acuities for 38.3  percent were better than 20/70, 43.2 percent had acui... (Source: SafetyLit)
Source: SafetyLit - May 25, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

New longer-term data reinforce safety of Roche ’s satralizumab in adults and adolescents with neuromyelitis optica spectrum disorder
Basel, 22 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new pooled pivotal satralizumab safety results for the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare, debilitating central nervous system disorder. These data are being presented at the 6th Annual Meeting of the European Academy of Neurology (EAN) and show satralizumab was well-tolerated in a broad patient population – including adolescents, for whom there is no approved medicine. Satralizumab is an investigational humanised monoclonal antibody that targets the interleukin-6 (IL-6) receptor, believed to play a key role in the i...
Source: Roche Media News - May 22, 2020 Category: Pharmaceuticals Source Type: news

New longer-term data reinforce safety of Roche ’s satralizumab in adults and adolescents with neuromyelitis optica spectrum disorder
Basel, 22 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) will present new pooled pivotal satralizumab safety results for the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare, debilitating central nervous system disorder. These data are being presented at the 6th Annual Meeting of the European Academy of Neurology (EAN) and show satralizumab was well-tolerated in a broad patient population – including adolescents, for whom there is no approved medicine. Satralizumab is an investigational humanised monoclonal antibody that targets the interleukin-6 (IL-6) receptor, believed to play a key role in the i...
Source: Roche Investor Update - May 22, 2020 Category: Pharmaceuticals Source Type: news

Visually impaired Nigerians struggle to navigate coronavirus challenges
Lawal Adebimpe knows she must remain a safe distance from people to help prevent the spread of the novel coronavirus in Nigeria. But her blindness means she usually holds people to navigate her way around the heaving megacity of Lagos. (Source: Reuters: Health)
Source: Reuters: Health - May 21, 2020 Category: Consumer Health News Tags: healthNews Source Type: news

$5 million supports research into neglected tropical diseases
(Washington University School of Medicine) Researchers at Washington University School of Medicine in St. Louis have received two grants from the National Institutes of Health (NIH) totaling more than $5 million to study two types of parasitic worm infection that cause devastating illness in millions of people worldwide. One project will focus on onchocerciasis, commonly known as river blindness. The second project will target fascioliasis, commonly found in cattle-farming operations. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 21, 2020 Category: Infectious Diseases Source Type: news

Correcting blindness
(Source: ScienceNOW)
Source: ScienceNOW - May 21, 2020 Category: Science Authors: Alderton, G. Tags: twis Source Type: news