NEI AGI Seminar: Human iPSC-derived 3D retinal tissue for stem cell-based therapies for retinal degenerative diseases
Dr. Canto-Soler completed her Ph.D. in Biomedical Sciences at Austral University in Argentina and a postdoctoral fellowship at the Wilmer Eye Institute, Johns Hopkins University. She joined the Wilmer faculty as a research associate in 2006 and was promoted to assistant professor in 2008. In July 2017 she joined the Department of Ophthalmology at the University of Colorado School of Medicine as the Doni Solich Family Chair in Ocular Stem Cell Research and the Director of CellSight – the Ocular Stem Cell and Regeneration Research Program. Over the years she has received several national and international awards including ...
Source: Videocast - All Events - November 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

NLM ADA Lovelace Lecture: Tackling Diabetic Retinopathy in a Safety Net Healthcare Setting with Telehealth and Machine Learning
NLM ADA Lovelace Lecture Diabetic retinopathy is the leading cause of blindness in working age adults in the United States. It is challenging to address in both rural and urban underserved settings, which suffer from shortages of eye specialists. This talk will describe the approach taken to address this condition in a medically underserved area (South Los Angeles) by researchers in the Center for Biomedical Informatics at Charles R. Drew University of Medicine and Science, using telehealth and machine learning on data from patient electronic health records. Omolola Ogunyemi, PhD, FACMI is the Director of Charles R. Drew U...
Source: Videocast - All Events - September 30, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Tackling Diabetic Retinopathy in a Safety Net Healthcare Setting with Telehealth and Machine Learning
Presentation Description: Diabetic retinopathy is the leading cause of blindness in working age adults in the United States. It is challenging to address in both rural and urban underserved settings, which suffer from shortages of eye specialists. This talk will describe the approach taken to address this condition in a medically underserved area (South Los Angeles) by researchers in the Center for Biomedical Informatics at Charles R. Drew University of Medicine and Science, using telehealth and machine learning on data from patient electronic health records. Speaker Bio: Omolola Ogunyemi, PhD, FACMI is the Director of ...
Source: Videocast - All Events - September 15, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

NEI Audacious Goals: Cytoplasmic material exchange between sensory neurons in vivo
Dr. Wallace is Director of Vision Sciences and Chair of the Vision Science Research Program at the Toronto Western Research Institute/University Health Network. She holds appointments in the Departments of Ophthalmology and Vision Sciences and Laboratory Medicine and Pathobiology, University of Toronto. A molecular and developmental biologist by training, she is recognized for her work on the role of Hedgehog signaling in neural progenitor proliferation in the central nervous system. Her lab is now applying this knowledge towards investigating the role of morphogen signaling in tumorigenesis and the development of cell-bas...
Source: Videocast - All Events - February 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

AGI Seminar in Neuroregeneration
Dr. Wallace is Director of Vision Sciences and Chair of the Vision Science Research Program at the Toronto Western Research Institute/University Health Network. She holds appointments in the Departments of Ophthalmology and Vision Sciences and Laboratory Medicine and Pathobiology, University of Toronto. A molecular and developmental biologist by training, she is recognized for her work on the role of Hedgehog signaling in neural progenitor proliferation in the central nervous system. Her lab is now applying this knowledge towards investigating the role of morphogen signaling in tumorigenesis and the development of cell-bas...
Source: Videocast - All Events - February 18, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

We are what we eat: nutrition, genes, cognition & deep learning in age-related macular degeneration
NIH Director's Wednesday Afternoon Lecture Series Age-related macular degeneration (AMD) is the leading cause of blindness in the United States and in the developed world. Two NIH-supported randomized clinical trials with 10 years of follow-up in nearly 10,000 participants demonstrated that nutritional supplements with antioxidant vitamins and minerals reduces the risk of progression to late AMD. Dietary data suggest the importance of the Mediterranean diet in reducing the risk of AMD, particularly fish consumption. The analyses of the genetic interaction with nutrition challenges the idea that you can eat away your geneti...
Source: Videocast - All Events - October 10, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

NEI Sayer Lecture: Clinical features and molecular basis of the cerebellar-retinal degenerative disorder SpinoCerebellar Ataxia type 7: From mechanism to therapy
NEI Sayer Lecture Spinocerebellar ataxia type 7 (SCA7) is an inherited neurological disorder characterized by cerebellar and retinal degeneration. SCA7 patients develop atrophy of the cerebellar cortex and the brainstem, and exhibit extensive loss of cerebellar Purkinje cells. An important feature of SCA7, that allows it to be distinguished from the 40+ other SCAs, is retinal degeneration. Full field electroretinograms of SCA7 patients reveal marked dysfunction of cone photoreceptor cells prior to rod photoreceptor abnormalities, establishing SCA7 as a cone-rod dystrophy. As retinal disease progresses, rod photoreceptors b...
Source: Videocast - All Events - April 11, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Living in the Cold -- Adaptations in Hibernation
NIH Neuroscience Series Seminar Dr. Li ’ s lab studies the structure and function of retinal synapses and circuits. Although they know the basic structure and major cell types of the retina, it remains much of a " black box " in terms of the connections and functions of these neurons. Their long-term research goal is to understand how the neuronal circuits are wired in this " black box " under normal conditions and how the circuits are altered during pathological processes. Both pieces of information will be crucial for the design of biological and/or prosthetic interventions aiming to restore vision in many types of bli...
Source: Videocast - All Events - September 14, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Author video abstract: De Patre et al. Visual and Motor Recovery After Cognitive Therapeutic Exercises in Cortical Blindness: A Case Study
No description available (Source: Journal of Neurologic Physical Therapy - Video)
Source: Journal of Neurologic Physical Therapy - Video - June 27, 2017 Category: Physiotherapy Source Type: video

Visual Restoration: Bridges and Gaps to Curing Blindness in Humans
NEI AGI Seminar Series in Neurorgenerative Medicine Dr. Andrew Huberman (Stanford University) presents " Visual Restoration: Bridges and Gaps to Curing Blindness in Humans "Air date: 1/24/2017 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 5, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

2015 Maurice B. Burg Lecture: Opening Doors Worldwide Through Medical Science
The major lesson I learned from a four-decade career in medical science is that we have a unique opportunity to make the world a better place. As a Johns Hopkins faculty member, our research group discovered the aquaporin water channels that facilitate the movement of water across cell membranes. This led to multiple international collaborations including studies with renal physiologists in Denmark, neuroscientists in Norway, structural biologists in Switzerland and Japan, and field workers in Africa. While the practical value of these discoveries is just emerging, valuable new preventive strategies and treatments for mu...
Source: Videocast - All Events - November 3, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video

Looking Inside the Adaptive Brain of the Blind
2015-2016 BSSR Lecture Series Within the setting of visual deprivation, the brain undergoes dramatic reorganization in both its structure and function. Furthermore, these neuroplastic changes are intimately related to compensatory sensory and perceptual behaviors observed in individuals who are blind. We will present how modern neuroimaging has helped reveal the relationship between the brain and behavior as it relates to blindness. We will also highlight differences between individuals who are visually impaired due to ocular causes as compared to those who have developmental damage to the visual cortex. For more informa...
Source: Videocast - All Events - September 8, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video