Management of dementia-related psychosis, agitation and aggression: a review of the pharmacology and clinical effects of potential drug candidates - Marcinkowska M, Śniecikowska J, Fajkis N, Paśko P, Franczyk W, Kołaczkowski M.
Along with cognitive decline, 90% of patients with dementia experience behavioral and psychological symptoms of dementia, such as psychosis, aggression, agitation, and depression. Atypical antipsychotics are commonly prescribed off-label to manage certain ... (Source: SafetyLit)
Source: SafetyLit - February 17, 2020 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Class 4 medicines defect information: Diamorphine hydrochloride BP 100 mg lyophilisate for solution for injection
Accord Healthcare Ltd has advised of an issue related to the expiry date for two batches of diamorphine hydrochloride BP 100 mg lyophilisate for solution for injection, which has not been encoded in 2 (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 17, 2020 Category: Drugs & Pharmacology Source Type: news

VOCs in Breath as a Biomarker for Adenomas, Colorectal Cancer VOCs in Breath as a Biomarker for Adenomas, Colorectal Cancer
Might exhaled volatile organic compounds potentially serve as non-invasive biomarkers for the detection of colorectal cancer and its precursor lesions?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 17, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

RPS welcomes NICE consultation on community pharmacy
We have welcomed a consultation from the National Institute for Health and Care Excellence (NICE) on a quality standard for Community pharmacies: promoting health and wellbeing. The guidelines highli (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 17, 2020 Category: Drugs & Pharmacology Source Type: news

Use of Electronic Records and Electronic Signatures in Clinical Investigations Under 21 CFR Part 11 – Questions and Answers
Guidance for Industry - Use of Electronic Records and Electronic Signatures in Clinical Investigations Under 21 CFR Part 11 – Questions and Answers (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

How FDA Plans to Help Consumers Capitalize on Advances in Science
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Susan Band Horwitz Wins Prestigious Cancer Research Award for Anti-Tumor Drug Discovery
February 14, 2020—(BRONX, NY)—Susan Band Horwtiz, Ph.D., distinguished professor of molecular pharmacology and the Rose C. Falkenstein Chair in Cancer Research at Albert Einstein College of Medicine, has been awarded the National Foundation for Cancer Research’s (NFCR) 2020 Szent-Györgyi Prize for Progress in Cancer Research. The honor recognizes her pioneering research establishing the mechanism of action of anti-tumor drugs, including Taxol, that are used to treat ovarian, breast, and lung cancers. (Source: Einstein News)
Source: Einstein News - February 14, 2020 Category: Universities & Medical Training Source Type: news

FDA Working to Lift Barriers to Generic Drug Competition
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Widens Scope of Navigator – Information Tool for Expanded Access
FDA Widens Scope of Navigator – Information Tool for Expanded Access (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA is Using Innovative Methods to Prevent Illegal Products with Hidden Drug Ingredients from Entering the United States
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Taking New Steps to Better Inform Physicians about Biosimilars Through Education about these Potentially Cost-Saving Options
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Takes Important Steps to Stem the Tide of Opioid Misuse and Abuse
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

APS BioGroup, Inc - 04/05/2018
Unapproved New Drugs/Misbranded (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: Center for Drug Evaluation and Research Source Type: news

Caution: Some Over-the-Counter Medicines May Affect Your Driving
Antihistamines and other OTC drugs can impair your ability to drive and operate machinery. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Benzocaine and Babies: Not a Good Mix
Parents should avoid using benzocaine products to relieve teething pain for children under 2. They are at risk for the disease methemoglobinemia. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Data Standards Program Strategic Plan and Board
The Data Standards Strategy reinforces CDER ’s ongoing commitment to the development, implementation, and maintenance of a comprehensive data standards program that will facilitate the efficient and effective review of regulatory submissions. This helps bring safe and effective products to market. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

CDER Data Standards Program
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 14, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Medicine Supply Notification - Levomepromazine 25mg/1ml solution for injection
The Department of Health and Social Care (DHSC) has issued the following Medicine Supply Notification... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 14, 2020 Category: Drugs & Pharmacology Source Type: news

Deblitane (Norethindrone Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 14, 2020 Category: Drugs & Pharmacology Source Type: news

Audenz ((Influenza A (H5N1) Monovalent Vaccine, Adjuvanted) Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 14, 2020 Category: Drugs & Pharmacology Source Type: news

Pemfexy (Pemetrexed Injection for Intravenous Use) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 14, 2020 Category: Drugs & Pharmacology Source Type: news

Trijardy XR (Empagliflozin, Linagliptin, and Metformin Hydrochloride Extended-release Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 14, 2020 Category: Drugs & Pharmacology Source Type: news

FDA Issues MiniMed600 Insulin Pump Recall FDA Issues MiniMed600 Insulin Pump Recall
If the pumps in question, models 630G and 670G, have broken or missing retainer rings, a potentially loose insulin cartridge could lead to incorrect dosing and possibly hyperglycemia or hypoglycemia.News Alerts (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - February 13, 2020 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Alert Source Type: news

FDA In Brief: FDA Requests Voluntary Withdrawal of Weight-Loss Medication After Clinical Trial Shows an Increased Occurrence of Cancer
FDA is requesting drug manufacturer Eisai Inc. to voluntarily withdraw its weight loss medication Belviq and Belviq XR (lorcaserin) from the U.S. market after a data analysis from a postmarket clinical trial showed that an increased occurrence of cancer. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Belviq, Belviq XR (lorcaserin) by Eisai: Drug Safety Communication - FDA Requests Withdrawal of Weight-Loss Drug
FDA has requested that the manufacturer voluntarily withdraw the weight-loss drug from the U.S. market because a safety clinical trial shows an increased occurrence of cancer. The drug manufacturer, Eisai Inc,. has submitted a request to voluntarily withdraw the drug. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA requests the withdrawal of the weight-loss drug Belviq, Belviq XR (lorcaserin) from the market
FDA has requested that the weight-loss drug Belviq, Belviq XR be withdrawn from the U.S. market because a safety clinical trial shows an increased occurrence of cancer. Stop taking the drug and talk to your health care professional if you have questions. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Buderer Drug Company Inc - 506509 - 05/01/2019
Compounding Pharmacy/Adulteration/Misbranding, Buderer Drug Company Inc (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

ABC Compounding Company Inc - 576953 - 05/02/2019
Failure to Comply with Drug Listing Requirements/Misbranded, ABC Compounding Company Inc (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

ABC Compounding Company Inc - 576953 - 04/18/2019
Failure to Comply with Drug Listing Requirements/Misbranded (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: Center for Drug Evaluation and Research Source Type: news

1ViZN LLC - 522724 - 08/23/2017
Unapproved New Drugs/Misbranded (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: Center for Food Safety and Applied Nutrition Source Type: news

FDA Commissioner Asks Staff for ‘More Forceful Steps’ to Stem the Opioid Crisis
FDA Commissioner Asks Staff for ‘More Forceful Steps’ to Stem the Opioid Crisis (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA Budget Matters: Investing in Advanced Domestic Manufacturing
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA is Advancing the Goals of the Orphan Drug Act
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Orange Book Preface
Preface to Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) provides info on how the book came to be, relevant terms and codes, user responsibilities and more. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Expanded Access: FDA Describes Efforts to Ease Application Process
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 13, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Class 2 Medicines recall: Accord-UK Ltd, Gliclazide 40 mg Tablets (Northstar Livery)
Accord-UK Limited is recalling all unexpired stock of Gliclazide 40 mg Tablets (Northstar Livery). (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 13, 2020 Category: Drugs & Pharmacology Source Type: news

Class 3 FMD Medicines Recall, Beconase Aqueous Nasal Spray, (Beclometasone Dipropionate 50 μg)
Glaxo Wellcome UK Ltd T/A GSK has informed the MHRA of an issue related to error in the decommissioning of a specified batch of Beconase Aqueous Nasal Spray. (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 13, 2020 Category: Drugs & Pharmacology Source Type: news

Much shorter radiation treatment found to be safe, effective for people with soft tissue sarcoma
In this study at UCLA, a national leader in the care of patients with sarcoma, researchers used a condensed five-day radiation regimen that considerably cuts down the length of treatment and the time to surgery.“Shortening the radiation therapy from five weeks to five days has been a very meaningful change for patients,” said lead author Dr. Anusha Kalbasi, assistant professor of radiation oncology in the division of molecular and cellular oncology. “Five weeks of daily treatments is a burdensome com mitment for patients. The daily back-and-forth can be expensive and time consuming, and it can really inte...
Source: UCLA Newsroom: Health Sciences - February 13, 2020 Category: Universities & Medical Training Source Type: news

U.S. Food and Drug Administration (FDA) Accepts for Priority Review Bristol-Myers Squibb ’s Biologics License Application (BLA) for Lisocabtagene Maraleucel (liso-cel) for Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma
PRINCETON, N.J.--(BUSINESS WIRE) February 13, 2020 --Bristol-Myers Squibb Company (NYSE: BMY) today announced that the U.S. Food and Drug Administration (FDA) has accepted for Priority Review its Biologics License Application (BLA) for lisocabtagene... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 13, 2020 Category: Drugs & Pharmacology Source Type: news

Public Health Alert - Coronavirus (2019n-CoV) Updated guidance from Public Health Wales and Chief Medical Officer for Wales (Wales only)
The Chief Medical Officer for Wales has issued an update guidance for all clinical staff encountering patients with respiratory infections arrived from overseas. Public Health Wales (PHW) has issued (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Class 4 Medicines Defect Information: Atrolak XL Prolonged-release tablets, all strengths (quetiapine fumarate)
Accord Healthcare Ltd has informed the Medicines and Healthcare Products Regulatory Agency (MHRA) that the Patient Information Leaflet (PIL)... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

New report aims to transform general practice in Wales
Transforming patient care in general practice settings is the aim of a new resource being launched today at the National Assembly for Wales. The resource, developed in partnership by the Royal Colleg (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Nausea and Vomiting and Immune Activation in Celiac Disease Nausea and Vomiting and Immune Activation in Celiac Disease
This findings of this study implicate nausea and vomiting as sentinel symptoms of acute gluten exposure in patients following a gluten-free diet.Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - February 12, 2020 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

Deblitane (Norethindrone Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Audenz ((Influenza A (H5N1) Monovalent Vaccine, Adjuvanted) Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Pemfexy (Pemetrexed Injection for Intravenous Use) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Palforzia ([Peanut (arachis hypogaea) Allergen Powder-dnfp] Powder for Oral Administration) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Wellbutrin (bupropion)
Title: Wellbutrin (bupropion)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 2/12/2020 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - February 12, 2020 Category: Drugs & Pharmacology Source Type: news

Health Fraud Scams
Learn how to spot health fraud and avoid it. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 11, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Medicine Supply Notification - Salbutamol 2mg/5ml syrup
The Department of Health and Social Care (DHSC) has issued the following Medicine Supply Notification... (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 11, 2020 Category: Drugs & Pharmacology Source Type: news