Acyclovir Capsules, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 21, 2019 Category: Drugs & Pharmacology Source Type: news

Acyclovir Tablets, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 21, 2019 Category: Drugs & Pharmacology Source Type: news

Haloperidol Tablets (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 21, 2019 Category: Drugs & Pharmacology Source Type: news

Statins Tied to Insulin Resistance, Higher Serum Fasting Insulin
THURSDAY, March 21, 2019 -- Individuals using statins may be at higher risk for hyperglycemia, insulin resistance, and eventually type 2 diabetes, according to a study published online March 5 in the British Journal of Clinical Pharmacology. Fariba... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 21, 2019 Category: Pharmaceuticals Source Type: news

Calls for greater pharmacist role in prescription drug dependency
RPS Wales haswelcomed areportcalling for NHS Wales to make better use of the expertise of pharmacists in cases ofprescriptiondrug dependence and withdrawal. The report is theresult of evidence gath (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - March 21, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Sunosi (solriamfetol) for Excessive Daytime Sleepiness Associated with Narcolepsy or Obstructive Sleep Apnea
DUBLIN, March 20, 2019 /PRNewswire/ -- Jazz Pharmaceuticals plc today announced that the U.S. Food and Drug Administration (FDA) approved Sunosi (solriamfetol) to improve wakefulness in adult patients with excessive daytime sleepiness associated... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 21, 2019 Category: Drugs & Pharmacology Source Type: news

Researchers identify potential new combination treatment for pancreatic cancer
FINDINGSResearchers from UCLA ’s Jonsson Comprehensive Cancer Center have identified a possible new therapeutic strategy using two types of drug inhibitors at once to treat one of the world’s deadliest cancers. The combination approach uses one drug that inhibits the process — known as lysosome — that allows cancer cells to recycle essential nutrients to survive, and another drug that blocks the pathway used to repair DNA. Researchers found the approach to be promising after testing it on pancreatic cancer cells and mice in the laboratory.BACKGROUNDPancreatic cancer, which is the third leading cause...
Source: UCLA Newsroom: Health Sciences - March 20, 2019 Category: Universities & Medical Training Source Type: news

Calcium Gluconate Injection (Updated - Resolved)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 20, 2019 Category: Drugs & Pharmacology Source Type: news

Cefotaxime Sodium (Claforan) Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 20, 2019 Category: Drugs & Pharmacology Source Type: news

Vincristine Sulfate (VINCASAR PFS) Injection, USP (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 20, 2019 Category: Drugs & Pharmacology Source Type: news

Vedolizumab Levels and Outcomes in Ulcerative Colitis Vedolizumab Levels and Outcomes in Ulcerative Colitis
This study aimed to characterize the relationship between vedolizumab exposure and response in ulcerative colitis, adjusted for variables known to affect drug clearance and serum concentration.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 20, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Older patients with Crohn's disease benefit from new medications
(Wiley) Combining medications that suppress the immune system has been successful in treating young patients with Crohn's disease, but some physicians have been reluctant to use this strategy in older patients because of concerns about safety. Now an Alimentary Pharmacology& Therapeutics study indicates that older patients can be safely and effectively treated with such combined immunosuppression as well. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 20, 2019 Category: International Medicine & Public Health Source Type: news

FDA Approves Zulresso (brexanolone) for the Treatment of Postpartum Depression
March 19, 2019 -- The U.S. Food and Drug Administration today approved Zulresso (brexanolone) injection for intravenous (IV) use for the treatment of postpartum depression (PPD) in adult women. This is the first drug approved by the FDA... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 19, 2019 Category: Drugs & Pharmacology Source Type: news

Company-led recall: Ozurdex 700 micrograms intravitreal implant in applicator (dexamethasone)
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a company-led recall for further batches of Ozurdex 700 micrograms intravitreal implant in applicator (dexamethasone) due to t (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - March 19, 2019 Category: Drugs & Pharmacology Source Type: news

GARDP and Evotec announce new partnership to discover novel antibiotics
(Drugs for Neglected Diseases Initiative) The Global Antibiotic Research and Development Partnership (GARDP) and Evotec AG have formed a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance. By joining forces, Evotec and GARDP will leverage their capabilities and networks to address drug-resistant bacterial infections. This includes bringing together GARDP's clinical expertise and sustainable access commitment with Evotec's leading drug discovery platform, expertise in medicinal chemistry and pharmacology as well as its world-leading collection of bacterial pathogens. (Source: E...
Source: EurekAlert! - Social and Behavioral Science - March 19, 2019 Category: International Medicine & Public Health Source Type: news

FDA Approves Genentech ’s Tecentriq in Combination With Chemotherapy for the Initial Treatment of Adults With Extensive-Stage Small Cell Lung Cancer
South San Francisco, CA -- March 18, 2019 -- Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that the U.S. Food and Drug Administration (FDA) approved Tecentriq (atezolizumab), in combination with carboplatin and... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Phone Intervention for Patients Most At Risk Improves HbA1c Phone Intervention for Patients Most At Risk Improves HbA1c
Pharmacist-led phone interventions to improve insulin adherence in patients with diabetes worked best when those at highest risk of noncompliance were targeted.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 18, 2019 Category: Drugs & Pharmacology Tags: Diabetes & Endocrinology News Source Type: news

Allergan Announces FDA Approval of Avycaz (ceftazidime and avibactam) for Pediatric Patients
DUBLIN, March 18, 2019 /PRNewswire/ -- Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) has approved the company's supplemental New Drug Application (sNDA) for Avycaz (ceftazidime and avibactam),... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Aminosalicylate Use in Patients With UC on Biologics Aminosalicylate Use in Patients With UC on Biologics
Is it efficacious and cost-effective to continue aminosalicylates in patients with ulcerative colitis who have been escalated to immunosuppressants, biologics, or oral small molecules?Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - March 18, 2019 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

Zostavax (Zoster Vaccine Live) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Namenda (Memantine HCL) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

lidocaine and prilocaine (EMLA)
Title: lidocaine and prilocaine (EMLA)Category: MedicationsCreated: 3/2/2005 12:00:00 AMLast Editorial Review: 3/18/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Tambocor (Flecainide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Romazicon (Flumazenil) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Apresoline (Hydralazine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 18, 2019 Category: Drugs & Pharmacology Source Type: news

Machine learning scientists to collaborate on AI-powered drug discovery
(InSilico Medicine, Inc.) The laboratories of Jianfeng Pei at Peking University and Alex Zhavoronkov at Insilico Medicine partner with Frontiers in Pharmacology, a leading open science platform on the research topic " AI for drug discovery and development " (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 18, 2019 Category: Biology Source Type: news

Machine Learning Approach Gives Insight on Toxin Exposure
Harvard Medical School investigators have developed a machine learning approach using high-quality, large-scale animal model data that sheds new light on the biology of the liver and kidneys after toxin exposure. The findings were recently published in Molecular Systems Biology, and reveal new mechanisms of toxin vulnerability and tolerance that may be broadly relevant to studies of human disease, the authors said. Researchers found nine distinct patterns of response to chemical exposure that the authors termed "disease states." These states shed light on the dynamics of toxin-induced liver and kidney injury, inc...
Source: MDDI - March 17, 2019 Category: Medical Devices Authors: MDDI Staff Tags: Digital Health Source Type: news

OTC Insomnia Supplements: The Latest Evidence OTC Insomnia Supplements: The Latest Evidence
Dietary supplements are used by millions of people seeking a good night's sleep, but which ones are safe and effective?Medscape Pharmacists (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 15, 2019 Category: Drugs & Pharmacology Tags: Pharmacist Ask the Expert Source Type: news

Flurazepam Hydrochloride Capsules (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 14, 2019 Category: Drugs & Pharmacology Source Type: news

chlorpheniramine and hydrocodone, Tussionex, TussiCaps, Tussionex Pennkinetic, Vituz
Title: chlorpheniramine and hydrocodone, Tussionex, TussiCaps, Tussionex Pennkinetic, VituzCategory: MedicationsCreated: 6/6/1999 12:00:00 AMLast Editorial Review: 3/14/2019 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - March 14, 2019 Category: Drugs & Pharmacology Source Type: news

Evoke Pharma Submits Response to FDA Review Letter for Gimoti NDA
SOLANA BEACH, Calif., March 14, 2019 (GLOBE NEWSWIRE) -- Evoke Pharma, Inc. (NASDAQ: EVOK), a specialty pharmaceutical company focused on treatments for gastrointestinal (GI) diseases, today announced that it has submitted its response to the U.S.... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 14, 2019 Category: Drugs & Pharmacology Source Type: news

Karyopharm Announces FDA Extension of Review Period for Selinexor New Drug Application
NEWTON, Mass., March 14, 2019 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a clinical-stage pharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 14, 2019 Category: Drugs & Pharmacology Source Type: news

FDA OKs Rocklatan, a New Once-Daily Eye Drop for Glaucoma FDA OKs Rocklatan, a New Once-Daily Eye Drop for Glaucoma
The netarsudil and latanoprost ophthalmic solution (Rocklatan) reduces elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension.FDA Approvals (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 14, 2019 Category: Drugs & Pharmacology Tags: Ophthalmology News Alert Source Type: news

Cefazolin Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Dicyclomine Oral Tablets/Capsules (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Enrichment Strategies for Clinical Trials to Support Approval of Human Drugs and Biological Products
Clinical/Medical (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Early Antiviral Therapy and Lymphoma Risk in Chronic HCV Early Antiviral Therapy and Lymphoma Risk in Chronic HCV
Chronic HCV infection has been linked to lymphoproliferative disorders. Can early PegIFN/RBV therapy reduce the risk?Alimentary Pharmacology & Therapeutics (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - March 13, 2019 Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news

Spravato (Esketamine Nasal Spray) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Clarinex-D 24hr (Desloratadine and Pseudoephedrine Sulfate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Transderm Scop (Scopolamine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 13, 2019 Category: Drugs & Pharmacology Source Type: news

Eisai and Imbrium Therapeutics Announce U.S. FDA Filing Acceptance of New Drug Application for Lemborexant for the Treatment of Insomnia
TOKYO and STAMFORD, Conn.– March 12, 2019– Eisai Co., Ltd. (CEO: Haruo Naito,“Eisai”) and Imbrium Therapeutics L.P. (Imbrium Therapeutics), a clinical-stage biopharmaceutical company and operating subsidiary of Purdue... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

Hydroxyzine Pamoate Oral Capsules (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

Olmesartan Medoxomil Tablets (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

Rescheduling of gabapentin and pregabalin to Schedule 3 Controlled Drugs from 1 April 2019
Gabapentin and pregabalin will be reclassified to Schedule 3 Controlled Drugs (CDs). This means from 1 April 2019: Prescriptions for gabapentin and pregabalin need to meet full prescription require (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Rocklatan (netarsudil and latanoprost ophthalmic solution) for the Reduction of Intraocular Pressure in Open-Angle Glaucoma or Ocular Hypertension
DURHAM, N.C.--(BUSINESS WIRE)--Mar. 12, 2019-- Aerie Pharmaceuticals, Inc. (NASDAQ:AERI) (Aerie or the Company), an ophthalmic pharmaceutical company focused on the discovery, development and commercialization of first-in-class therapies for the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

Using wearable devices in clinical trials
Brandy Chittester, chief of clinical operations, IMARC Globally, more than 325 million people own wearable, connected devices, and more than 2.5 billion own smartphones. Using wearable devices in clinical trials can bring huge benefits, however, there are also concerns. Here’s a look at how researchers are using wearable devices — and what you should consider before using them in your own research. How wearable devices are advancing medicine Right now, ClinicalTrials.gov, a global database of clinical trials, lists nearly 200 trials with “wearable devices” or “wearable technology” in t...
Source: Mass Device - March 12, 2019 Category: Medical Devices Authors: Danielle Kirsh Tags: Blog IMARC Source Type: news

Allergan Announces FDA Acceptance of New Drug Application for Ubrogepant for the Acute Treatment of Migraine
DUBLIN, March 11, 2019 /PRNewswire/ -- Allergan plc (NYSE: AGN) today announced that the U.S. Food and Drug Administration (FDA) has accepted the company's New Drug Application (NDA) for ubrogepant for the acute treatment of migraine in adults.... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 12, 2019 Category: Drugs & Pharmacology Source Type: news

Amlodipine Besylate and Olmesartan Medoxomil Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 11, 2019 Category: Drugs & Pharmacology Source Type: news

Eprosartan Mesylate Tablets (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 11, 2019 Category: Drugs & Pharmacology Source Type: news

Lisinopril (Prinivil) Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - March 11, 2019 Category: Drugs & Pharmacology Source Type: news