FDA Expands Indication for Soliqua 100/33 (insulin glargine and lixisenatide injection) to Include Type 2 Diabetes Patients Uncontrolled on Oral Antidiabetic Medicines
BRIDGEWATER, N.J., Feb. 27, 2019 /PRNewswire/ -- The U.S. Food and Drug Administration (FDA) has approved the expanded use of Soliqua 100/33 (insulin glargine and lixisenatide injection) 100 Units/mL and 33 mcg/mL. Previously approved for use as an... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 27, 2019 Category: Drugs & Pharmacology Source Type: news

Karyopharm Announces Outcome of FDA Advisory Committee Meeting Reviewing Selinexor for the Treatment of Patients with Triple Class Refractory Multiple Myeloma
NEWTON, Mass., Feb. 26, 2019 (GLOBE NEWSWIRE) -- Karyopharm Therapeutics Inc. (Nasdaq:KPTI), a clinical-stage pharmaceutical company, today announced that the U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) met to... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 27, 2019 Category: Drugs & Pharmacology Source Type: news

Why melatonin is a powerful anticancer indolamine
(Natural News) A team of researchers from Iran suggests that melatonin has powerful anticancer properties. In their study, which was published in the journal Toxicology and Applied Pharmacology, they looked at the molecular anti-angiogenesis pathways mediated by melatonin and the responsible mechanisms in different forms of cancers both in vitro and in vivo. Melatonin is... (Source: NaturalNews.com)
Source: NaturalNews.com - February 27, 2019 Category: Consumer Health News Source Type: news

Sign up for Type 2 Diabetes Prevention Week
Type 2 Diabetes Prevention Week is a joint campaign from NHS England, Public Health England and Diabetes UK. It's part of the NHS Diabetes Prevention Programme andaims to raise awareness of Type 2 (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Heparin Sodium Injection (Heparin Sodium Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Remeron SolTab (Mirtazapine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Colazal (Balsalazide) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Tylenol-Codeine (Acetaminophen and Codeine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Supplemental New Drug Application to Expand Cinvanti (aprepitant) Label for IV Push
SAN DIEGO, Feb. 26, 2019 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX), a commercial-stage biotechnology company focused on improving the lives of patients by developing best-in-class treatments to address some of the most important unmet... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Gloperba (colchicine) for Prophylaxis of Adult Gout Flares
WOBURN, Mass.--(BUSINESS WIRE)--February 26, 2019 ROMEG Therapeutics, an innovative drug development company focused on alternative formulations to better meet clinical and patient needs, today announced that the U.S. Food and Drug Administration... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Sugar amplifies the effects of an anticancer compound used in Traditional Chinese Medicine
(Natural News) Research has found that an extract from the “thunder god vine” contains triptolide, a small molecule that can stop cells from multiplying. Jun O. Liu, Ph.D. is a professor of pharmacology and molecular sciences at the Johns Hopkins University School of Medicine and a member of the Johns Hopkins Kimmel Cancer Center. He and... (Source: NaturalNews.com)
Source: NaturalNews.com - February 25, 2019 Category: Consumer Health News Source Type: news

Safety trial finds risk of blood clots in the lungs and death with higher dose of tofacitinib (Xeljanz, Xeljanz XR) in rheumatoid arthritis patients; FDA to investigate
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Deadly diet drug DNP can kill
DNP(2,4-dinitrophenol) is an industrial chemical used in pesticides and explosives which is unfit for human consumption but sold illegally via the internet for weight loss. It acts as a'fat burne (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Azasite (Azithromycin Ophthalmic Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Allegra-D (Fexofenadine HCl and Pseudoephedrine HCl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Platinol-AQ (Cisplatin Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Fioricet with Codeine (Butalbital Acetaminophen Caffeine Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Gralise (Gabapentin Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Ticlid (Ticlopidine Hcl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Alkermes and Biogen Announce U.S. Food and Drug Administration Acceptance of Diroximel Fumarate New Drug Application for Multiple Sclerosis
DUBLIN, Ireland and CAMBRIDGE, Mass., Feb. 25, 2019 (GLOBE NEWSWIRE) -- Alkermes plc (Nasdaq: ALKS) and Biogen Inc. (Nasdaq: BIIB) today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Lonsurf (trifluridine/tipiracil) for Adult Patients with Previously Treated Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
PRINCETON, N.J., February 25, 2019– Taiho Oncology, Inc. today announced that the United States Food and Drug Administration (FDA) has approved Lonsurf as a treatment for adult patients with metastatic gastric or gastroesophageal junction... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 25, 2019 Category: Drugs & Pharmacology Source Type: news

Belladonna and Opium Suppository (Updated - Resolved)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 22, 2019 Category: Drugs & Pharmacology Source Type: news

Fludrocortisone Acetate Tablets (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 22, 2019 Category: Drugs & Pharmacology Source Type: news

Verapamil HCl Extended-Release Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 22, 2019 Category: Drugs & Pharmacology Source Type: news

Zolpidem Tartrate Extended Release Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 22, 2019 Category: Drugs & Pharmacology Source Type: news

A missing gene makes a big difference in patients ’ recovery from mild stroke
More than 6 million Americans live with disabilities following a stroke. Even mild strokes can leave survivors with arm and leg weakness, poor muscle control and memory lapses that worsen with age. Now UCLA neuroscientists have found that patients born without a gene called CCR5 recover better from mild stroke than patients with the gene. The team partnered with Israeli researchers to study the missing gene ’s effect on brain function.Published Feb. 21 in the journal Cell,  the findings could lead to the first pill to reverse the physical and mental aftermath of mild stroke.“This is the first time tha...
Source: UCLA Newsroom: Health Sciences - February 21, 2019 Category: Universities & Medical Training Source Type: news

FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat)
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Physostigmine Salicylate Injection, USP (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Valacyclovir Hydrochloride Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Relentless rise in prescription charges harms patients, says RPS in England
Today the Government announced a rise in prescription charges to£9 per item from 1st April. Commenting on the rise, Chairof the RPS English Board Sandra Gidley said:“The consequences of (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Pharmacists should have equal access to wellbeing support
Responding to the announcement from the Department of Health and Social Care to provide better mental health and wellbeing support to NHS staff, Chair of the RPS in England Sandra Gidley said:&ldquo (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Artiss (Fibrin Sealant (Human)] Frozen Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Eskata (Hydrogen Peroxide Topical Solution) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Wixela Inhub (Fluticasone Propionate and Salmeterol Inhalation Powder) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 21, 2019 Category: Drugs & Pharmacology Source Type: news

Relief of Heartburn in Patients With Erosive Esophagitis Relief of Heartburn in Patients With Erosive Esophagitis
Does a new potassium-competitive acid blocker, vonoprazan, provide more rapid relief of heartburn than standard treatment with a proton-pump inhibitor?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 21, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Juv & eacute;derm Ultra XC (Hyaluronic Acid Injectable Gel) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

Egaten (Triclabendazole Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

Juv & eacute;derm Voluma XC (Hyaluronic Acid Injectable Gel Dermal Filler) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

Alyq (Tadalafil Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Esperoct (turoctocog alfa pegol, N8-GP) for Hemophilia A
Bagsværd, Denmark, 19 February 2019 - Novo Nordisk today announced that the US Food and Drug Administration (FDA) has approved the Biologics License Application for Esperoct for the treatment of adults and children with hemophilia A. Esperoct... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

FDA Approves Keytruda (pembrolizumab) for the Adjuvant Treatment of Patients with Melanoma with Involvement of Lymph Node(s) Following Complete Resection
KENILWORTH, N.J.--(BUSINESS WIRE) February 19, 2019 --Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration (FDA) has approved Keytruda, Merck’s anti-PD-1 therapy, for... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 20, 2019 Category: Drugs & Pharmacology Source Type: news

Hydroxyprogesterone Caproate Injection (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - February 19, 2019 Category: Drugs & Pharmacology Source Type: news

AbbVie Announces New Drug Application Accepted for Priority Review by FDA for Upadacitinib for Treatment of Moderate to Severe Rheumatoid Arthritis
NORTH CHICAGO, Ill., Feb. 19, 2019 /PRNewswire/ -- AbbVie (NYSE: ABBV), a research-based global biopharmaceutical company, has announced that the U.S. Food and Drug Administration (FDA) has accepted for priority review its New Drug Application (NDA)... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - February 19, 2019 Category: Drugs & Pharmacology Source Type: news

Speakers announced for 2019 Experimental Biology Meeting
(Experimental Biology) Renowned scientists including Nobel laureates, research pioneers and celebrated educators will convene at the Experimental Biology (EB) 2019 meeting, to be held April 6-9 in Orlando. Bringing together more than 12,000 life scientists in one interdisciplinary community, EB showcases the latest advances in anatomy, biochemistry, molecular biology, investigative pathology, pharmacology and physiology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 19, 2019 Category: Cancer & Oncology Source Type: news

Risk of acute pancreatitis with carbimazole use (MHRA Drug Safety Update)
The MHRA has released a Drug Safety Update about the risk of acute pancreatitis with the use of products containing carbimazole and thiamazole. If acute pancreatitis occurs during treatment with ca (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 18, 2019 Category: Drugs & Pharmacology Source Type: news

Class 4 defect information: Atropine Sulfate 3mg/10ml Solution for injection in pre-filled syringe
Aguettant Limited has advised that there is an error in the Patient Information Leaflet for Atropine Sulfate 3mg/10ml Solution for injection in pre-filled syringe. (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 18, 2019 Category: Drugs & Pharmacology Source Type: news

The RPS Fellows Dinner date announced
The Fellows Dinner is a celebration of those in the profession who have gained recognition from their peers for their contribution to pharmacy. We also see this as a celebration of the diversity of th (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 18, 2019 Category: Drugs & Pharmacology Source Type: news

RPS Faculty Review
We'd like to thank you for your involvementand commitment to RPS Faculty, and to those who have contributed to the review of the annual submission process. We are now widening the review of Facult (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - February 18, 2019 Category: Drugs & Pharmacology Source Type: news

Tuberculosis: Commandeering a bacterial 'suicide' mechanism
(CNRS) The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The European team of scientists behind this discovery is coordinated by researchers from the Institute of Pharmacology and Structural Biology (IPBS--CNRS/UPS) and the European Molecular Biology Laboratory (EMBL). Their findings are published in Molecular Cell. The team is now seeking to appropriate this 'suicide' mechanism for therapeutic purposes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 18, 2019 Category: International Medicine & Public Health Source Type: news

Preventing 'cell wall remodeling' may hold key to defeating intransigent super bugs
(Case Western Reserve University) With a $3.34 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, Edward W. Yu, Ph.D., professor of pharmacology at Case Western Reserve University School of Medicine, is conducting research that could help physicians better understand how bacteria such as B. multivorans resist antibiotics, potentially leading to improved treatments. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 18, 2019 Category: Infectious Diseases Source Type: news