Reducing Risk of Esophageal Cancer in Barrett's Esophagus Reducing Risk of Esophageal Cancer in Barrett's Esophagus
Patients with Barrett's esophagus have a high risk of developing esophageal adenocarcinoma. Can PPIs and H2 receptor antagonists mitigate the risk?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Janssen Submits New Drug Application to U.S. FDA Seeking Approval of Erdafitinib for the Treatment of Metastatic Urothelial Cancer
HORSHAM, Pa., Sept. 18, 2018 /PRNewswire/ -- The Janssen Pharmaceutical Companies of Johnson& Johnson announced today that a New Drug Application (NDA) has been submitted to the U.S. Food and Drug Administration (FDA) seeking approval of... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 18, 2018 Category: Drugs & Pharmacology Source Type: news

Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors
G protein–coupled receptors (GPCRs) are major drug targets. Developing a method to measure the activities of GPCRs is essential for pharmacology and drug screening. However, it is difficult to measure the effects of a drug by monitoring the receptor on the cell surface; thus, changes in the concentrations of downstream signaling molecules, which depend on the signaling pathway selectivity of the receptor, are often used as an index of receptor activity. We show that single-molecule imaging analysis provides an alternative method for assessing the effects of ligands on GPCRs. Using total internal reflection fluorescen...
Source: Signal Transduction Knowledge Environment - September 18, 2018 Category: Science Authors: Yanagawa, M., Hiroshima, M., Togashi, Y., Abe, M., Yamashita, T., Shichida, Y., Murata, M., Ueda, M., Sako, Y. Tags: STKE Research Articles Source Type: news

Monurol (Fosfomycin) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 17, 2018 Category: Drugs & Pharmacology Source Type: news

Nipride RTU (Sodium Nitroprusside Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 17, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Approves Ajovy (fremanezumab-vfrm) for Preventive Treatment of Migraine
September 14, 2018 -- Today, the US Food and Drug Administration (FDA) approved Ajovy (fremanezumab-vfrm) for the preventive treatment of migraine in adults. Ajovy is the second FDA-approved preventive migraine treatment in a new class of drugs that... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Approves Xelpros (latanoprost ophthalmic emulsion) to Treat Open-angle Glaucoma or Ocular Hypertension
MUMBAI, India& PRINCETON, N.J.--(BUSINESS WIRE) September 14, 2018 --Sun Pharmaceutical Industries Ltd. and Sun Pharma Advanced Research Company Ltd. (SPARC) today announced U.S. Food and Drug Administration (USFDA) approval for the New Drug... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

Diphenhydramine Injection (New - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

RPS in Scotland welcomes new programme by Scottish Government
The Royal Pharmaceutical Society (RPS) in Scotland would like to welcome the publishing of the Scottish Government’s new programme for 2018-19“Delivering for Today, Investing for Tomorrow (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

Miraluma (Technetium Tc99m sestamibi) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

Vivaglobin (Immune Globulin Subcutaneous (Human)) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 14, 2018 Category: Drugs & Pharmacology Source Type: news

Ardelyx Submits New Drug Application for Tenapanor for IBS-C
FREMONT, Calif., Sept. 13, 2018 /PRNewswire/ -- Ardelyx, Inc. (Nasdaq: ARDX), today announced the submission of its New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) requesting U.S. marketing authorization of tenapanor for... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Approves Subcutaneous Formulation of Actemra for Use in Active Systemic Juvenile Idiopathic Arthritis (SJIA)
South San Francisco, CA -- September 13, 2018 -- Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today that the U.S. Food and Drug Administration (FDA) has approved the subcutaneous (SC) formulation of Actemra... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Approves Lumoxiti (moxetumomab pasudotox-tdfk) for Hairy Cell Leukemia
September 13, 2018 -- The U.S. Food and Drug Administration today approved Lumoxiti (moxetumomab pasudotox-tdfk) injection for intravenous use for the treatment of adult patients with relapsed or refractory hairy cell leukemia (HCL) who have... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

Testosterone 1% Gel (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

Daclatasvir Tablets (New - Discontinuation)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

October 10, 2018: Meeting of the Oncologic Drugs Advisory Committee
Meeting Announcement (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

One responsible pharmacist per pharmacy
Adding informationto the RPS statement on its consultation response on hospital dispensing errors and superintendent and responsible pharmacists, RPS President Ash Soni said:“The RPS has alway (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

RPS signs new mental health charter
The RPS today signed The Charter for Equal Health as a partner of Equally Well UK, a group of over 50 organisations including government bodies, statutory organisations and charities dedicated to redu (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

Drugs: Questions to Ask Your Doctor or Pharmacist about Your Drugs
Title: Drugs: Questions to Ask Your Doctor or Pharmacist about Your DrugsCategory: MedicationsCreated: 3/27/2001 12:00:00 AMLast Editorial Review: 9/13/2018 12:00:00 AM (Source: MedicineNet Medications General)
Source: MedicineNet Medications General - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

Association Between PPIs and Hepatocellular Carcinoma Association Between PPIs and Hepatocellular Carcinoma
Might long-term use of proton pump inhibitors increase the risk of hepatocellular carcinoma?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 13, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Acorda Announces FDA Extends Inbrija NDA Review Period
ARDSLEY, N.Y.--(BUSINESS WIRE)--September 13, 2018 -- Acorda Therapeutics, Inc. (Nasdaq:ACOR) today announced that the U.S. Food and Drug Administration (FDA) has extended the Prescription Drug User Fee Act (PDUFA) goal date for its review of the... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - September 13, 2018 Category: Drugs & Pharmacology Source Type: news

RPS responds to consultation on hospital dispensing errors and superintendent and responsible pharmacists
The Royal Pharmaceutical Society has submitted its response to the government's consultationon hospital dispensing errors and superintendent and responsible pharmacists. The two-part consultation (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 12, 2018 Category: Drugs & Pharmacology Source Type: news

Company led recall: Mydriasert 0.28mg/5.4mg Ophthalmic Insert
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a company led recall for a specific batch of Mydriasert 0.28mg/5.4mg Ophthalmic Insert (Thea Pharmaceuticals) as it is labelle (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 12, 2018 Category: Drugs & Pharmacology Source Type: news

Drug for pancreatic cancer developed by college of pharmacy researchers
A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly disease. Ruiwen Zhang, M.D., Ph.D. and Robert L. Boblitt Endowed Professor in Drug Discovery, has published his findings, along with research associate professor of pharmacology Wei Wang, M.D., Ph.D., in Cancer Research Journal. (Source: World Pharma News)
Source: World Pharma News - September 12, 2018 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Tiglutik (Riluzole Oral Suspension) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 12, 2018 Category: Drugs & Pharmacology Source Type: news

Axona (Caprylidene Prescription Medical Food) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 11, 2018 Category: Drugs & Pharmacology Source Type: news

RPS England welcomes check before you tick
NHS England and the NHS Business Services Authority (NHS BSA) have launched a campaign, Check Before You Tick, to help people understand their eligibility for free prescriptions. NHS BSA checks claims (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 11, 2018 Category: Drugs & Pharmacology Source Type: news

First- and Second-line Biologic Therapies for Crohn's Disease First- and Second-line Biologic Therapies for Crohn's Disease
Several biologic agents are now available for first- and second- line treatment of Crohn's disease, but head-to-head trials are lacking. This meta-analysis aimed to compare efficacy of these agents.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 11, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Valsartan Tablets (Updated - Currently in Shortage)
Drug Shortage (Source: FDA Drug Shortages)
Source: FDA Drug Shortages - September 10, 2018 Category: Drugs & Pharmacology Source Type: news

Iressa (Gefitinib) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 10, 2018 Category: Drugs & Pharmacology Source Type: news

Lanoxin (Digoxin Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 10, 2018 Category: Drugs & Pharmacology Source Type: news

Changes in the architecture around cancer cells can fuel their spread
FINDINGSUCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption. The study shows that acute changes in a single component of the extracellular matrix can trigger a very rapid change in the metabolism and migration of the cell.  BACKGROUNDGiven its importance in the growth and migration in cancer cells, scientists have intensely studied how glucose metabolism can be regulated in response to a variety of both internal and external cues. But little research has focuse...
Source: UCLA Newsroom: Health Sciences - September 8, 2018 Category: Universities & Medical Training Source Type: news

La FDA advierte acerca de casos poco frecuentes de una infecci ó n grave del á rea genital con los inhibidores del SGLT2 para la diabetes
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

La FDA advierte acerca de casos poco frecuentes de una infecci ón grave del área genital con los inhibidores del SGLT2 para la diabetes
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Astepro (Azelastine Hydrochloride Nasal Spray) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Delstrigo (Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate Tablets) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Cefotetan (Cefotetan for Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Jivi (Antihemophilic Factor (Recombinant), PEGylated-aucl for Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Trilisate (Choline Magnesium Trisalicylate) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

Artane (Trihexyphenidyl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

FDA Approves Cassipa (buprenorphine and naloxone) Sublingual Film as Maintenance Treatment for Opioid Dependence
September 7, 2018 -- The U.S. Food and Drug Administration today approved Cassipa (buprenorphine and naloxone) sublingual film (applied under the tongue) for the maintenance treatment of opioid dependence. This action provides a new dosage strength... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 7, 2018 Category: Drugs & Pharmacology Source Type: news

ITF Pharma Announces FDA Approval of Tiglutik (riluzole) Oral Suspension for the Treatment of Amyotrophic Lateral Sclerosis (ALS)
BERWYN, Pa., Sept. 6, 2018 /PRNewswire/ -- ITF Pharma, a U.S.-based specialty pharmaceutical company and a subsidiary of Italfarmaco, a privately-held European specialty pharmaceutical company, committed to investing in and commercializing impactful... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - September 6, 2018 Category: Drugs & Pharmacology Source Type: news

Altreno (Tretinoin Lotion) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 6, 2018 Category: Drugs & Pharmacology Source Type: news

Xerava (Eravacycline for Injection) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 6, 2018 Category: Drugs & Pharmacology Source Type: news

Tonocard (Tocainide HCl) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 6, 2018 Category: Drugs & Pharmacology Source Type: news

Anxiety and Depressive Symptoms in Adolescents With IBD Anxiety and Depressive Symptoms in Adolescents With IBD
How prevalent is anxiety and depression in young persons with inflammatory bowel disease, and what clinical and demographic factors might contribute to increased risk?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 6, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Bee venom may help treat eczema
(Wiley) Bee venom and its major component, melittin, may be effective treatments for atopic dermatitis (or eczema), according to a British Journal of Pharmacology study. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 6, 2018 Category: International Medicine & Public Health Source Type: news

Unnecessary medicine use in patients with lung cancer at the end of life
(Wiley) Individuals with advanced lung cancer often have other comorbid conditions, and many may be on complex, costly, and even inappropriate medication regimens. A new British Journal of Clinical Pharmacology study examined the extent to which such patients are prescribed medications with questionable benefit. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 6, 2018 Category: Cancer & Oncology Source Type: news

Do you know your heart age?
Public Health England (PHE) have today launched a Heart Age Test which encourages adults aged 30 and over to take a free online test which determines if your heart is at a (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - September 4, 2018 Category: Drugs & Pharmacology Source Type: news