Fight Aging! Newsletter, July 13th 2020

In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue damage takes place. The usual conclusion to such research is provided, which is to head off into the space of developing pharmaceuticals to mimic some fraction of the effects of exercise on metabolism. Given that calorie restriction mimetic research has been ongoing for more than 20 years, with all too little to show for it, no-one should be holding their breath awaiting viable exercise mimetic drugs with meaningfully large effect sizes. Exercise reduced the harmful overgrowth of blood vessels in the eyes of lab mice by up to 45%. This tangle of blood vessels is a key contributor to macular degeneration and several other eye diseases. The study represents the first experimental evidence showing that exercise can reduce the severity of macular degeneration, a leading cause of vision loss. "There has long been a question about whether maintaining a ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs