Real neurons are noisy. Can neural implants figure that out?
(Duke University) Signals sent from the retina to the brain have a lot of background noise, yet we see the world clearly. Duke researchers show that to achieve visual clarity the brain must accurately measure how this noise is distributed across neurons when processing the signals sent down the optic nerve. These results are likely to shape the design of future retinal prosthetics and other brain-machine interfaces. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 15, 2020 Category: International Medicine & Public Health Source Type: news

Catching the red eye: A retrospective review of factors associated with retinal hemorrhage in child physical abuse - Moody S, Casar AM, Jenkins T, Farooqui Z, Shebesta K, Kotagal M, Falcone RA.
BACKGROUND/PURPOSE: Accurate identification of child physical abuse is crucial during the evaluation of injured children. Retinal hemorrhages (RH) are used for diagnosis, but clear criteria for screening with direct fundoscopic exam are lacking. We sought ... (Source: SafetyLit)
Source: SafetyLit - September 8, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Retinal periphery is insensitive to sudden transient motion - Anstis S.
Peripherally viewed targets moved around against a background of random dynamic noise. Slow movements were visible, fast movements were not. Thus, a target that repetitively drifted to the right and snapped back appeared to drift endlessly to the right wit... (Source: SafetyLit)
Source: SafetyLit - September 7, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Hypervitaminosis a following the ingestion of fish liver: report on 3 cases from the poison control center in Marseille - Schmitt C, Domange B, Torrents R, de Haro L, Simon N.
We report 3 cases of vitamin A poisoning after fish liver ingest... (Source: SafetyLit)
Source: SafetyLit - September 2, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Vitamin B12 deficiency: Two signs felt on the body warning of dangerously low levels
VITAMIN B12 deficiency is far more common than many realise and when the body lacks in this essential vitamin a number of unusual warning symptoms may occur. Feeling either of these two signs on your body could indicate a deficiency. (Source: Daily Express - Health)
Source: Daily Express - Health - August 27, 2020 Category: Consumer Health News Source Type: news

Serum Retinol and Risk of Overall and Site-Specific Cancer Serum Retinol and Risk of Overall and Site-Specific Cancer
This study aimed to elucidate the association between serum retinol and cancer risk.American Journal of Epidemiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 25, 2020 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

Nonaccidental trauma in pediatric patients: evidence-based screening criteria for ophthalmologic examination - Ip SS, Zafar S, Liu TYA, Srikumaran D, Repka MX, Goldstein MA, Woreta FA.
BACKGROUND: Ophthalmologic examination is included in the work-up for pediatric nonaccidental trauma (NAT) when there is concern for retinal hemorrhage. However, dilated fundus examination entails patient discomfort and prohibition of assessment of pupilla... (Source: SafetyLit)
Source: SafetyLit - August 24, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy
In developed countries, the leading causes of blindness such as diabetic retinopathy are characterized by disorganized vasculature that can become fibrotic. Although many such pathological vessels often naturally regress and spare sight-threatening complications, the underlying mechanisms remain unknown. Here, we used orthogonal approaches in human patients with proliferative diabetic retinopathy and a mouse model of ischemic retinopathies to identify an unconventional role for neutrophils in vascular remodeling during late-stage sterile inflammation. Senescent vasculature released a secretome that attracted neutrophils an...
Source: ScienceNOW - August 20, 2020 Category: Science Authors: Binet, F., Cagnone, G., Crespo-Garcia, S., Hata, M., Neault, M., Dejda, A., Wilson, A. M., Buscarlet, M., Mawambo, G. T., Howard, J. P., Diaz-Marin, R., Parinot, C., Guber, V., Pilon, F., Juneau, R., Laflamme, R., Sawchyn, C., Boulay, K., Leclerc, S., Abu Tags: Cell Biology, Medicine, Diseases, Online Only r-articles Source Type: news

Vitamin deficiency warning: What do your eyes look like? ‘Foamy white growths’ to avoid
VITAMIN deficiencies can lead to a number of "unpleasant" symptoms, but may be difficult to spot. You should consider adding more vitamin A-rich foods to your diet if your eyes develop these "foamy, white growths". Should you speak to a doctor? (Source: Daily Express - Health)
Source: Daily Express - Health - August 19, 2020 Category: Consumer Health News Source Type: news

Contrast sensitivity and retinal straylight after alcohol consumption: effects on driving performance - Casares-L ópez M, Castro-Torres JJ, Martino F, Ortiz-Peregrina S, Ortiz C, Anera RG.
In this study, we aimed to investigate the effects of alcohol intake on visual function and driving performance, as well as on the relationship between these. A total of 40 healthy participants took part in three experimental sessions: one baseline session... (Source: SafetyLit)
Source: SafetyLit - August 17, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
Zinc finger protein St18 was initially reported as candidate tumor suppressor gene, and also suggested that fibroblast St18 positively regulates NF-kappaB activation. Despite the pleiotropic functions of St18, little is known about its roles in macrophages. Here, we report that myeloid St18 is a potent inhibitor of VEGF-A. Mice lacking St18 in myeloid lineages exhibit increased retinal vasculature with enhanced serum VEGF-A concentrations. Despite the normal activation of NF-kappaB target genes, these mice are highly susceptible to LPS-induced shock, polymicrobial sepsis, and experimental colitis, accompanied by enhanced v...
Source: Current Awareness Service for Health (CASH) - August 5, 2020 Category: Consumer Health News Source Type: news

RBP4, a Potential Biomarker of Frailty in HIV RBP4, a Potential Biomarker of Frailty in HIV
Might higher levels of retinol-binding protein 4 predict frailty in HIV-infected patients?HIV Medicine (Source: Medscape Hiv-Aids Headlines)
Source: Medscape Hiv-Aids Headlines - July 24, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Media News - July 22, 2020 Category: Pharmaceuticals Source Type: news

Phase III data show Roche ’s Port Delivery System with ranibizumab enabled over 98% of patients to go six months between treatments for neovascular age-related macular degeneration
Basel, 22 July 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced detailed results from the phase III Archway study evaluating its investigational Port Delivery System with ranibizumab (PDS) for the treatment of neovascular or “wet” age-related macular degeneration (nAMD), a leading cause of blindness globally.1 In Archway, 98.4% of PDS patients were able to go six months without needing additional treatment and achieved vision outcomes equivalent to patients receiving monthly ranibizumab eye injections, a current standard of care. In the study, PDS was generally well-tolerated, with a favourable benefit...
Source: Roche Investor Update - July 22, 2020 Category: Pharmaceuticals Source Type: news

Determining the tractional forces on vitreoretinal interface using computer simulation model in abusive head trauma - Suh DW, Song HH, Mozafari H, Thoreson WB.
BACKGROUND: Abusive head trauma (AHT) is the leading cause of infant death and long-term morbidity from injury. The ocular consequences of AHT are controversial, and the pathophysiology of retinal research findings is still not clearly understood. It has b... (Source: SafetyLit)
Source: SafetyLit - July 18, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Interim Six-Month Data of RPGR Gene Therapy Shows Significant Vision Improvement in Patients Living with X-Linked Retinitis Pigmentosa
Click to Access Audio Press ReleaseRARITAN, NJ, July 17, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today six-month data from the ongoing Phase 1/2 trial (NCT03252847) of its investigational gene therapy for the treatment of inherited retinal disease X-linked retinitis pigmentosa (XLRP). The interim data showed that low and intermediate doses of the investigational adeno-associated virus retinitis pigmentosa GTPase regulator (AAV-RPGR) were generally well-tolerated and indicated significant improvement in vision. Initial data on the novel AAV-RPGR asset, jointly developed with Meir...
Source: Johnson and Johnson - July 17, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

St18 is a negative regulator of VEGF
(National Institutes of Natural Sciences) A research team led by Kenta Maruyama M.D., Ph.D. from National Institute for Physiological Sciences explored the role of St18 in the regulation of VEGF expression. Mice lacking St18 in myeloid lineages are highly susceptible to septic shock. These mice also exhibit increased retinal vasculature with enhanced serum VEGF concentrations, and pharmacological inhibition of VEGF signaling rescues the high mortality rate of septic shock. These findings suggest that St18 is a negative regulator of VEGF. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 14, 2020 Category: International Medicine & Public Health Source Type: news

Fat cell hormone boosts potential of stem cell therapy
(Osaka University) Mesenchymal stem cell (MSC) therapy has shown promising results in the treatment of conditions ranging from liver cirrhosis to retinal damage, but results can be variable. Using a mouse heart failure model, researchers led by Osaka University found that levels of a fat cell-derived hormone called adiponectin in the host significantly affect the efficacy of MSC therapy. Administration of a drug that increases adiponectin in combination with MSCs is therefore likely to significantly improve the clinical outcome. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 10, 2020 Category: Biology Source Type: news

When Can You Use A Fingerprint to Identify Someone?
Discussion Biometrics uses “biological characteristics or behavioral features to recognize an individual.” Using biometric data requires acquisition of data of sufficient quantity and quality for recognition and comparison, and the biometric data needs to remain stable over time (i.e. – the person should be able to be recognized in the future using the data. Data acquisition and storage cost and size are also important variables. Privacy and security are also paramount considerations. Biometrics use in pediatric patients has several applications including: Newborn tracking -using biometrics for iden...
Source: PediatricEducation.org - July 6, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Rethink Food Security and Nutrition Following Covid-19 Pandemic
By Jomo Kwame Sundaram and Wan Manan MudaKUALA LUMPUR, Malaysia, Jul 2 2020 (IPS) The Covid-19 crisis has had several unexpected effects, including renewed attention to food security concerns. Earlier understandings of food security in terms of production self-sufficiency have given way to importing supplies since late 20th century promotion of trade liberalization. Jomo Kwame SundaramTransnational food business Disruption of transnational food supply chains and the devastation of many vulnerable livelihoods by policy responses to the Covid-19 pandemic have revived interest in earlier understandings of food self-sufficien...
Source: IPS Inter Press Service - Health - July 2, 2020 Category: International Medicine & Public Health Authors: Jomo Kwame Sundaram and Wan Manan Muda Tags: Development & Aid Economy & Trade Food Security and Nutrition Food Sustainability Global Headlines Health Humanitarian Emergencies Poverty & SDGs TerraViva United Nations Source Type: news

Progressive MS Linked to Faster Retinal Atrophy Than RRMS
TUESDAY, June 30, 2020 -- Progressive multiple sclerosis (PMS) is associated with faster retinal atrophy than relapsing-remitting MS (RRMS), independent of age, according to a study published in the June issue of the Annals of Neurology. Elias S.... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 30, 2020 Category: Pharmaceuticals Source Type: news

Blood Pressure, Retinal Vessel Diameters Connected in Children
MONDAY, June 29, 2020 -- Higher blood pressure is connected to narrowing of retinal arterioles in young children, according to a study published online June 29 in Hypertension. Giulia Lona, from the University of Basel in Switzerland, and colleagues... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 29, 2020 Category: Pharmaceuticals Source Type: news

New eye drops may prevent a common cause of blindness
(Columbia University Irving Medical Center) New eye drops could prevent vision loss after retinal vein occlusion, a major cause of blindness for millions of adults, a study by Columbia University researchers has found. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

The Critical Role of Women in Avoiding a Covid-19 “Food Pandemic” in sub-Saharan Africa
Credit: Kristin Palitza/IPSBy Gaudiose MujawamariyaANTANANARIVO, Madagascar, Jun 24 2020 (IPS) As infections with Covid-19 appear to be intensifying in sub-Saharan Africa (SSA), fears of severe food shortages have prompted experts to warn that the region may be “on the brink of a hunger pandemic.” Efforts are intensifying to rally a major global response. But averting what some experts believe could be a food crisis of immense proportions requires paying close attention to an often overlooked feature of food security in the region: African women play a large and growing role in all aspects of the region’s...
Source: IPS Inter Press Service - Health - June 24, 2020 Category: International Medicine & Public Health Authors: Gaudiose Mujawamariya Tags: Africa Food & Agriculture Gender Headlines Health TerraViva United Nations Source Type: news

Study of decreased serum levels of retinol binding protein 4 in major depressive disorder - Yao Q, Li Y.
BACKGROUND: Studies in western populations find that obesity and depression are positively correlated. Adipokines secreted by adipose tissue may serve as the crosstalk link between peripheral tissue and central nervous system, which mediates the relationsh... (Source: SafetyLit)
Source: SafetyLit - June 22, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Study sheds light on why retinal ganglion cells are vulnerable to glaucoma
(AlphaMed Press) Millions of sufferers of glaucoma might someday benefit from a study released in STEM CELLS in which a " disease in a dish " stem cell model was used to examine the mechanism in glaucoma that causes retinal ganglion cells (RGCs) to degenerate, resulting in loss of vision. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2020 Category: International Medicine & Public Health Source Type: news

FDA Approves Added Safety Info for Brolucizumab (Beovu) Label FDA Approves Added Safety Info for Brolucizumab (Beovu) Label
The FDA approved the addition of safety information about the risk for retinal vasculitis and/or retinal vascular occlusion in patients receiving the drug.News Alerts (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - June 16, 2020 Category: Drugs & Pharmacology Tags: Ophthalmology News Alert Source Type: news

A vitamin A analog may help treat diabetic retinopathy
(Elsevier) Diabetic retinopathy is a common complication of diabetes and a leading cause of blindness among the working-age population. A new study in The American Journal of Pathology reports that visual function in diabetic mice was significantly improved after treatment with a single dose of visual chromophore 9-cis-retinal, a vitamin A analog that can form a visual pigment in the retina cells, thereby producing a light sensitive element of the retina. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 11, 2020 Category: International Medicine & Public Health Source Type: news

The mystery of visual stability
(Tohoku University) We move our eyes several times per second. These fast eye movements, called saccades, create large image shifts on the retina -- making our visual system work hard to maintain a stable perceptual world. Remapping the retinal image compensates for this; however, errors in actual eye movements cause image shifts, even with remapping. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - June 11, 2020 Category: International Medicine & Public Health Source Type: news

Retinitis pigmentosa research probes role of the enzyme DHDDS in this genetic disease
(University of Alabama at Birmingham) Researchers who made a knock-in mouse-model of the genetic disorder retinitis pigmentosa 59, or RP59, expected to see retinal degeneration and retinal thinning. As reported in the journal Cells, they surprisingly found none, calling into question the commonly accepted -- though never proved -- mechanism for RP59. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 11, 2020 Category: International Medicine & Public Health Source Type: news

Retinal hemorrhages in abusive head trauma - Hellgren K, Fahnehjelm K.
Brain injuries due to abusive head trauma (AHT) in infants are not rare and they are probably under-diagnosed. Retinal hemorrhages (RH) constitute a cardinal symptom of AHT and AHT is the most common cause of RH in infants next to childbirth. Retinoschisis... (Source: SafetyLit)
Source: SafetyLit - June 11, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

A genetic mechanism for sexual dichromatism in birds
Sexual dichromatism, a difference in coloration between males and females, may be due to sexual selection for ornamentation and mate choice. Here, we show that carotenoid-based dichromatism in mosaic canaries, a hybrid phenotype that arises in offspring of the sexually dichromatic red siskin and monochromatic canaries, is controlled by the gene that encodes the carotenoid-cleaving enzyme β-carotene oxygenase 2 (BCO2). Dichromatism in mosaic canaries is explained by differential carotenoid degradation in the integument, rather than sex-specific variation in physiological functions such as pigment uptake or transport. T...
Source: ScienceNOW - June 11, 2020 Category: Science Authors: Gazda, M. A., Araujo, P. M., Lopes, R. J., Toomey, M. B., Andrade, P., Afonso, S., Marques, C., Nunes, L., Pereira, P., Trigo, S., Hill, G. E., Corbo, J. C., Carneiro, M. Tags: Evolution, Genetics reports Source Type: news

What Causes Free Peritoneal Fluid?
Discussion Peritoneal fluid is normal. It decreases the friction of the peritoneum covering abdominal and pelvic organs and helps to protect them and allow their movement. A normal amount of peritoneal fluid is expected on radiological evaluation. Increased peritoneal fluid is a continuum and is concerning as a wide variety of pathological causes are associated with it such as abdominal trauma and appendicitis. At the far end of the scale is ascites that is the accumulation of free fluid more than 25 ml. It is usually associated with abdominal distension but fluid must accumulate before distension can occur and therefore i...
Source: PediatricEducation.org - June 8, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Restoring light sensitivity using tunable near-infrared sensors
Enabling near-infrared light sensitivity in a blind human retina may supplement or restore visual function in patients with regional retinal degeneration. We induced near-infrared light sensitivity using gold nanorods bound to temperature-sensitive engineered transient receptor potential (TRP) channels. We expressed mammalian or snake TRP channels in light-insensitive retinal cones in a mouse model of retinal degeneration. Near-infrared stimulation increased activity in cones, ganglion cell layer neurons, and cortical neurons, and enabled mice to perform a learned light-driven behavior. We tuned responses to different wave...
Source: ScienceNOW - June 4, 2020 Category: Science Authors: Nelidova, D., Morikawa, R. K., Cowan, C. S., Raics, Z., Goldblum, D., Scholl, H. P. N., Szikra, T., Szabo, A., Hillier, D., Roska, B. Tags: Medicine, Diseases, Neuroscience reports Source Type: news

Long-term outcomes of pediatric traumatic cataracts and retinal detachments due to self-inflicted injuries - Felfeli T, Mireskandari K, Ali A.
PURPOSE: To report the characteristics and longitudinal visual outcomes of traumatic cataracts and retinal detachments in children with self-inflicted injury. METHODS: A retrospective case series of pediatric patients at a tertiary care center who sust... (Source: SafetyLit)
Source: SafetyLit - May 30, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Investor Update - May 27, 2020 Category: Pharmaceuticals Source Type: news

Roche ’s Port Delivery System with ranibizumab shows positive phase III results in neovascular age-related macular degeneration
Basel, 27 May 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced positive topline results from the phase III Archway study, evaluating Port Delivery System with ranibizumab (PDS) in people living with neovascular or “wet” age-related macular degeneration (nAMD). PDS is a permanent refillable eye implant, approximately the size of a grain of rice, which continuously delivers a customised formulation of ranibizumab over a period of months. The Archway trial met its primary endpoint, demonstrating that patient s with PDS who received refills every six months achieved visual acuity outcomes equivalent to tho...
Source: Roche Media News - May 27, 2020 Category: Pharmaceuticals Source Type: news

USC's Mark Humayun wins IEEE Medal for Innovations in Healthcare Technology
(Keck School of Medicine of USC) Mark Humayun, MD, PhD, director of the USC Dr. Allen and Charlotte Ginsburg Institute for Biomedical Therapeutics and co-director of the USC Roski Eye Institute, was awarded the 2020 Medal for Innovations in Healthcare Technology by the Institute of Electrical and Electronics Engineers (IEEE). Humayun was honored for his pioneering work in engineering and utilizing prosthetic devices to treat retinal neurodegenerative diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2020 Category: International Medicine & Public Health Source Type: news

Retinal texture could provide early biomarker of Alzheimer's disease
(Duke University) Biomedical engineers at Duke University have devised a new imaging device capable of measuring both the thickness and texture of the various layers of the retina. The advance could be used to detect a biomarker of Alzheimer's disease, potentially offering a widespread early warning system for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 14, 2020 Category: International Medicine & Public Health Source Type: news

Study: Vitamin A intake may help lower skin cancer risk
(Natural News) The vitamin A family consists of a group of fat-soluble nutrients commonly referred to as retinoic acids. These include retinoids such as retinol, a common ingredient in skincare products, retinal, a molecule necessary for vision and retinyl esters, the storage form of retinol. Well-known for their ability to improve vision, these compounds are... (Source: NaturalNews.com)
Source: NaturalNews.com - May 13, 2020 Category: Consumer Health News Source Type: news

Optina Diagnostics receives 510(k) clearance from U.S. FDA for its MHRC-C1, permitting hyperspectral imaging of the retina
MONTREAL, May 13, 2020 -- (Healthcare Sales & Marketing Network) - Optina Diagnostics announces today that it received 510(k) clearance for its ophthalmic camera, the Mydriatic Hyperspectral Retinal Camera (MHRC-C1), by the U.S. Food and Drug Administrati... Devices, Ophthalmology, FDA Optina Diagnostics, ophthalmic camera, Mydriatic Hyperspectral Retinal Camera (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 13, 2020 Category: Pharmaceuticals Source Type: news

Rapid Review: Diabetic retinopathy screening during the COVID-19 pandemic, CEBM
People with diabetes (PWD) are included in the group at increased risk of severe illness from coronavirus (COVID-19) and have been advised to observe stringent social distancing measures.(1) This creates a difficult situation for PWD and their Health Care Providers (HCP) as PWD require an annual review including retinal screening as part of their screening for complications, which involves a physical visit to a community or hospital facility or an eye clinic. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 12, 2020 Category: Consumer Health News Source Type: news

A noncanonical inhibitory circuit dampens behavioral sensitivity to light
Retinal ganglion cells (RGCs) drive diverse, light-evoked behaviors that range from conscious visual perception to subconscious, non–image-forming behaviors. It is thought that RGCs primarily drive these functions through the release of the excitatory neurotransmitter glutamate. We identified a subset of melanopsin-expressing intrinsically photosensitive RGCs (ipRGCs) in mice that release the inhibitory neurotransmitter -aminobutyric acid (GABA) at non–image-forming brain targets. GABA release from ipRGCs dampened the sensitivity of both the pupillary light reflex and circadian photoentrainment, thereby shiftin...
Source: ScienceNOW - April 30, 2020 Category: Science Authors: Sonoda, T., Li, J. Y., Hayes, N. W., Chan, J. C., Okabe, Y., Belin, S., Nawabi, H., Schmidt, T. M. Tags: Neuroscience reports Source Type: news

Retinal ganglion cells that release GABA
(Source: ScienceNOW)
Source: ScienceNOW - April 30, 2020 Category: Science Authors: Stern, P. Tags: Neuroscience twis Source Type: news

Eat safe: The takeaway on takeout (and other food)
In the weeks  since the safer-at-home ordinance went into effect in Los Angeles, we’ve had to learn to do a lot of things differently. The ways in which we study, work, communicate and interact physically with each other have all changed dramatically.So too with how we eat and shop for food. Yet even with limited trips to the market  and most restaurants turning to takeout and delivery service, many of us still have questions about how to best handle the food we bring into our homes.We turned toCatherine Carpenter, a professor of medicine, nursing and public health at UCLA ’s Center for Human Nutritio...
Source: UCLA Newsroom: Health Sciences - April 29, 2020 Category: Universities & Medical Training Source Type: news

Second Sight Gives Clearer Picture of Strategy Going Forward
Second Sight Medical Products provided an update on its strategic options and gave some clarity on a plan going forward. The Sylmar, CA-based company noted its situation was fluid and would explore options that include securing additional funding and exploring business alternatives that may include partnering, acquiring, investing in, or combining with businesses that may or may not be in a related industry. In a press release, the visual prosthesis firm’s acting CEO Matthew Pfeffer noted the company had been able to attract interest from third parties.   “Since taking over a...
Source: MDDI - April 28, 2020 Category: Medical Devices Authors: Omar Ford Tags: Business Implants Source Type: news

Medical Retinal Management Plans during COVID-19, RCOphth
The Royal College of Ophthalmologists (RCOphth) has produced guidance as a pragmatic approach to maintain care for those patients who need it while deferring care for those patients who can wait. Individual eye departments may institute their own guidelines. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 24, 2020 Category: Consumer Health News Source Type: news

The Future of Retinal Imaging The Future of Retinal Imaging
A new review explores the potential new role imaging technology could have in the detection and management of retinal diseases.Current Opinion in Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 22, 2020 Category: Consumer Health News Tags: Ophthalmology Journal Article Source Type: news

Getting Back Pain While Working From Home? An Ergonomics Expert Offers Advice
Even before the COVID-19 pandemic struck, roughly 1 in 6 U.S. workers, some 26 million people, worked either partly or fully from home. Now that number has grown significantly, as states are requiring non-essential employees to stay home. If you’re one of these people, you may be noticing new aches and pains that you did not experience at the office. That’s because even though it isn’t mandated, many companies follow an ANSI-HFS standard in the design of their computer workstations, furnishing the office with the ergonomic furniture and accessories. Most residential settings, however, simply don’t h...
Source: TIME: Health - April 15, 2020 Category: Consumer Health News Tags: Uncategorized COVID-19 feature Source Type: news

In reply: Predicting abusive head trauma - Cowley LE, Pfeiffer H, Babl F, Kemp AM.
The first issue relates to the author ’s comments that ‘the authors derived likelihoods even when one or more features were unknown (usually rib fractures and retinal haemorrhage at this stage of care). As this data is not missing at random, multipl... (Source: SafetyLit)
Source: SafetyLit - April 11, 2020 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news