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Structural insights into ion conduction by channelrhodopsin 2
We present high-resolution structures of ChR2 and the C128T mutant, which has a markedly increased open-state lifetime. The structure reveals two cavities on the intracellular side and two cavities on the extracellular side. They are connected by extended hydrogen-bonding networks involving water molecules and side-chain residues. Central is the retinal Schiff base that controls and synchronizes three gates that separate the cavities. Separate from this network is the DC gate that comprises a water-mediated bond between C128 and D156 and interacts directly with the retinal Schiff base. Comparison with the C128T structure r...
Source: ScienceNOW - November 23, 2017 Category: Science Authors: Volkov, O., Kovalev, K., Polovinkin, V., Borshchevskiy, V., Bamann, C., Astashkin, R., Marin, E., Popov, A., Balandin, T., Willbold, D., Büldt, G., Bamberg, E., Gordeliy, V. Tags: Biochemistry, Online Only r-articles Source Type: news

Dexamethasone Does Not Improve Vision in Persistent Diabetic Macular Edema Dexamethasone Does Not Improve Vision in Persistent Diabetic Macular Edema
Adding dexamethasone to continued ranibizumab treatment reduces retinal thickness but does not improve vision in patients with persistent diabetic macular edema (DME), according to results from a phase 2 randomized trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 20, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

How about a peanut butter and kale sandwich? Study shows that peanut butter enhances the vitamin A value of kale
(Natural News) It looks like aside from the classic peanut butter and jelly sandwich, there’s another — and healthier — way to enjoy peanut butter. According to a recent study, adding peanut butter to kale can boost the latter’s vitamin A value. According to researchers from South Korea, U.S., and Zimbabwe, peanut butter can help... (Source: NaturalNews.com)
Source: NaturalNews.com - November 20, 2017 Category: Consumer Health News Source Type: news

Chemical burns of the eye: the role of retinal injury and new therapeutic possibilities - Dohlman CH, Cade F, Regatieri CV, Zhou C, Lei F, Crnej A, Harissi-Dagher M, Robert MC, Papaliodis GN, Chen D, Aquavella JV, Akpek EK, Aldave AJ, Sippel KC, D ʼAmico DJ, Dohlman JG, Fagerholm P, Wang L, Shen LQ, González-Andrades M, Chodosh J, Kenyon KR, Foster CS, Pineda R, Melki S, Colby KA, Ciolino JB, Vavvas DG, Kinoshita S, Dana R, Paschalis EI.
PURPOSE: To propose a new treatment paradigm for chemical burns to the eye - in the acute and chronic phases. METHODS: Recent laboratory and clinical data on the biology and treatment of chemical burns are analyzed. RESULTS: Corneal blindne... (Source: SafetyLit)
Source: SafetyLit - November 17, 2017 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news

Stem Cell Therapy Shows Promise for Retinal Degeneration Stem Cell Therapy Shows Promise for Retinal Degeneration
Retinal pigment epithelial cells derived from human embryonic stem cells can be safely transplanted into the eyes of patients with retinal degeneration, with early signs of vision gain.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 17, 2017 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

After cooking, biofortified corn and eggs retain nutrient needed to prevent blindness
(American Chemical Society) Fortified and biofortified foods are at the forefront of efforts to combat vitamin A deficiency worldwide. But little is known about what influence processing may have on the retention of vitamin A precursors in these foods. Now in a study appearing in ACS Omega, scientists report that a high percentage of these healthful substances -- in some cases, almost all -- can survive cooking, depending on the preparation method.   (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 15, 2017 Category: Biology Source Type: news

Genetic treatment for blindness may soon be reality
(American Academy of Ophthalmology) Patients who had lost their sight to an inherited retinal disease could see well enough to navigate a maze after being treated with a new gene therapy, according to research presented today at AAO 2017, the 121st Annual Meeting of the American Academy of Ophthalmology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 10, 2017 Category: International Medicine & Public Health Source Type: news

FDA puts Second Sight Medical ’ s next-gen Orion ‘ bionic eye ’ on the fast track
Second Sight Medical (NSDQ:EYES) said today that the FDA put its Orion “bionic eye” on the fast track to approval. The Orion device is a cortical visual prosthesis that uses a camera and a brain implant to bypass the optic nerve in visually impaired patients. The federal safety watchdog put the device on its expedited access pathway, giving Sylmar, Calif.-based Second Sight priority review, greater interactive review for both its investigational device exemption and pre-market approval bids, plus more emphasis on post-market studies rather than pre-market clinical work. The FDA will also assign a cross-discipli...
Source: Mass Device - November 8, 2017 Category: Medical Devices Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Optical/Ophthalmic Regulatory/Compliance Second Sight Source Type: news

Genetically engineered "golden rice" suffers "metabolic meltdown" and devastating yield plunge as GE technology goes horribly wrong
(Natural News) Supporters of genetically modified organisms (GMOs) have long claimed that Golden Rice is key in alleviating vitamin A deficiency, but it turns out that’s not at all the case. According to a new report by Indian researchers, the genes necessary to produce Golden Rice cause unintended side effects, Independent Science News reported recently.... (Source: NaturalNews.com)
Source: NaturalNews.com - November 7, 2017 Category: Consumer Health News Source Type: news

Stem Cell Therapy Among Hot Topics at AAO 2017 Stem Cell Therapy Among Hot Topics at AAO 2017
A potential treatment for two eye conditions that currently have none -- inherited retinal disease and dry age-related macular degeneration -- will be among the most anticipated research presented at AAO 2017.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 3, 2017 Category: Consumer Health News Tags: Ophthalmology News Source Type: news

Retinal Sensitivity Linked to Cognitive Status in T2DM
Retinal sensitivity assessed by microperimetry is correlated with neurodegeneration parameters (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 31, 2017 Category: Psychiatry Tags: Endocrinology, Neurology, Ophthalmology, Pathology, Psychiatry, Radiology, Geriatrics, Journal, Source Type: news

Women and Malnutrition in Africa
In conclusion, it is arguable that there are improved impacts on nutrition if agricultural interventions are targeted to women and when specific work is done around women’s empowerment (for example, through behaviour change communication), mediated through women’s time use, women’s own health and nutrition status, and women’s access to and control over resources as well as intrahousehold decision-making power. That this may be dismissed out of hand is not unlikely either, given the persistence of male dominance.The post Women and Malnutrition in Africa appeared first on Inter Press Service. (Source:...
Source: IPS Inter Press Service - Health - October 31, 2017 Category: International Medicine & Public Health Authors: Raghav Gaiha and Vani Kulkarni Tags: Africa Aid Climate Change Food & Agriculture Gender Headlines Health Poverty & SDGs TerraViva United Nations Women's Health Source Type: news

Endogenous retinoid X receptor ligands in mouse hematopoietic cells
The retinoid X receptor α (RXRA) has been implicated in diverse hematological processes. To identify natural ligands of RXRA that are present in hematopoietic cells, we adapted an upstream activation sequence–green fluorescent protein (UAS-GFP) reporter mouse to detect natural RXRA ligands in vivo. We observed reporter activity in diverse types of hematopoietic cells in vivo. Reporter activity increased during granulocyte colony-stimulating factor (G-CSF)–induced granulopoiesis and after phenylhydrazine (PHZ)–induced anemia, suggesting the presence of dynamically regulated natural RXRA ligands in he...
Source: Signal Transduction Knowledge Environment - October 31, 2017 Category: Science Authors: Niu, H., Fujiwara, H., di Martino, O., Hadwiger, G., Frederick, T. E., Menendez-Gutierrez, M. P., Ricote, M., Bowman, G. R., Welch, J. S. Tags: STKE Research Articles Source Type: news

5 Easy-to-miss signs of vitamin D deficiency: Are YOU getting enough?
(Natural News) Vitamin D is a nutrient that your body produces when your skin absorbs sunlight, earning the nickname “sunshine vitamin.” Despite the name however, vitamin D is technically a pro-hormone, and not a vitamin. Your body cannot create vitamins by itself, therefore you need to rely on food and supplement for your vitamin intake. However,... (Source: NaturalNews.com)
Source: NaturalNews.com - October 30, 2017 Category: Consumer Health News Source Type: news

Allergan ’ s intravitreal implant wins approval in China
Allergan (NYSE:AGN) said today that it landed an imported drugs license from the Chinese FDA to market its dexamethasone intravitreal implant, Ozurdex, as a treatment for adults with macular edema following branch retinal vein occlusion or central retinal vein occlusion. The Dublin-based pharma giant touted its therapy as the first intravitreal injection approved for RVO in China. Get the full story at our sister site, Drug Delivery Business News. The post Allergan’s intravitreal implant wins approval in China appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - October 30, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Implants Optical/Ophthalmic Pharmaceuticals Regulatory/Compliance Wall Street Beat Allergan Inc. Source Type: news

Vitamin A
(Source: MayoClinic.com Full Feed)
Source: MayoClinic.com Full Feed - October 24, 2017 Category: Consumer Health News Source Type: news

3-D Retina Organoid Challenge
Proud SponsorThe National Eye Institute has its sights set on stimulating researchers to move rapidly toward treatments for retinal diseases. We need your scientific expertise: compete in a Challenge to develop a physiologically-competent3-D retina organoid model.Check us out on theirSponsor's Page. (Source: Neuromics)
Source: Neuromics - October 23, 2017 Category: Neuroscience Tags: 3-D Retinal Organoids Human Retinal Microvascular Endothelial Cells NEI Source Type: news

Protein regulates vitamin A metabolic pathways, prevents inflammation
(Case Western Reserve University) A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation. The discovery links diet to inflammatory diseases, like Crohn's disease and inflammatory bowel syndromes, and could inform nutritional interventions. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 23, 2017 Category: Biology Source Type: news

What is Usher Syndrome?
Discussion Over 7000 diseases are considered rare disorders according to the National Organization for Rare Disorders® (NORD, rarediseases.org). NORD is a patient advocacy organization dedicated to individuals with rare diseases and the organizations that serve them. They have information on about 1200 rare diseases on their website (https://rarediseases.org/for-patients-and-families/information-resources/rare-disease-information/). Hearing loss (HL) is not rare and is a common problem across the ages. It affects 360 million people worldwide which is about 5% of the population. There are many causes of hearing loss an...
Source: PediatricEducation.org - October 23, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

MassDevice.com +5 | The top 5 medtech stories for October 19, 2017
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. This surgical glue seals wounds in 60 seconds A potentially life-saving surgical glue that is highly elastic and adhesive can quickly seal wounds in seconds without the need for common staples or sutures. The surgical glue, cal...
Source: Mass Device - October 19, 2017 Category: Medical Devices Authors: MassDevice Tags: News Well Plus 5 Source Type: news

Pixium Vision wins French approval for Prima sub-retinal implant study
Pixium Vision (EPA:PIX) said today it won approval from France’s regulatory agency to launch a feasibility clinical study of its next-gen Prima sub-retinal implant in patients with advanced dry age-related macular degeneration. The Prima system is a next-gen wireless implant with a micro photovoltaic chip designed to be implanted under the retina to convert pulsed near-infra-red invisible light received from external glasses with an integrated mini-camera into electrical signals transmitted to the brain through the optic nerve, the company said. The system is designed to treat retinal dystrophies with a foc...
Source: Mass Device - October 19, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Optical/Ophthalmic Pixium Vision Source Type: news

FDA Advisory Committee Unanimously Recommends Approval of Investigational Luxturna (voretigene neparvovec) for Patients with Biallelic RPE65-mediated Inherited Retinal Disease
PHILADELPHIA, Oct. 12, 2017 (GLOBE NEWSWIRE) -- Spark Therapeutics (NASDAQ:ONCE), a fully integrated gene therapy company dedicated to challenging the inevitability of genetic disease, announced today that the U.S. Food and Drug Administration ’s... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - October 19, 2017 Category: Drugs & Pharmacology Source Type: news

Ocular Allergy Meds Fall Short: Ophthalmology Times
(MedPage Today) -- Also, adaptive optics could provide window into understanding retinal diseases (Source: MedPage Today Ophthalmology)
Source: MedPage Today Ophthalmology - October 18, 2017 Category: Opthalmology Source Type: news

Second Sight wins go-ahead for German Argus II study in better-sighted RP patients
This study has the potential to change the management of patients with RP and, if successful, greatly expand the patient population who can benefit from this treatment, and for whom the Argus II could be a solution,” Dr. Walter of Germany’s Universitätsklinikum Aachen said in a prepared statement. In July, Second Sight said its Argus II retinal prosthesis system won expanded reimbursement coverage from the Centers for Medicare and Medicaid Services in 11 additional states and the District of Columbia. See the best minds in medtech live at DeviceTalks West, Dec. 11–12 in Orange County, Calif. The post...
Source: Mass Device - October 17, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Optical/Ophthalmic Regulatory/Compliance Second Sight Source Type: news

FDA advisory panel recommends approval of Spark Therapeutics' gene therapy
A Food and Drug Administration advisory committee voted Thursday to recommend approval of Spark Therapeutics ’ application for its experimental gene therapy developed to treat vision loss caused by an inherited retinal disease. The vote by the Cellular, Tissue and Gene Therapies Advisory Committee was unanimous. Spark's stock price was up about 2 percent at $86.20 per share in after-hours trading short ly after the committee's vote was announced. The company, which was spun out of Children’s… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - October 12, 2017 Category: American Health Authors: John George Source Type: news

FDA advisory panel recommends approval of Spark Therapeutics' gene therapy
A Food and Drug Administration advisory committee voted Thursday to recommend approval of Spark Therapeutics ’ application for its experimental gene therapy developed to treat vision loss caused by an inherited retinal disease. The vote by the Cellular, Tissue and Gene Therapies Advisory Committee was unanimous. Spark's stock price was up about 2 percent at $86.20 per share in after-hours trading short ly after the committee's vote was announced. The company, which was spun out of Children’s… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 12, 2017 Category: Biotechnology Authors: John George Source Type: news

Mini form of replacement gene can delay degeneration in leber congenital amaurosis
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study demonstrates success in using a shortened form of the CEP290 gene for gene therapy in a mouse model of Leber congenital amaurosis type 10 (LCA10), a retinal degenerative disorder that causes childhood blindness. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 5, 2017 Category: International Medicine & Public Health Source Type: news

Outfox Your “ Aging ” Gene
Some people just seem to have all the luck when it comes to getting old. Like my 83-year-old patient who drinks a little too much Scotch, but still has a 3-handicap in golf. Or the 108-year-old who goes through a gallon of ice cream every week. If you ask them how they do it, they’ll give credit to their good genes… and there is some truth to it. We all have something called a FOXO3 gene. It helps protect us against aging. German researchers at the Christian-Albrechts University studied the FOXO3 gene in 380-plus centenarians, more than 600 people in their 90s, and more than 700 people between the ages of...
Source: Al Sears, MD Natural Remedies - October 4, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Health Nutrition longevity Source Type: news

How a diet of potato, meat and Cheerios made boy go BLIND
The strange case, involving medics at The Hospital for Sick Children in Toronto, was published in JAMA Pediatrics Clinical Challenge. It stemmed from a lack of vitamin A. (Source: the Mail online | Health)
Source: the Mail online | Health - October 4, 2017 Category: Consumer Health News Source Type: news

FDA: Blindness Risk From Compounded Vancomycin Eye Injections FDA: Blindness Risk From Compounded Vancomycin Eye Injections
The FDA is warning against intraocular injections of vancomycin either alone or in combination with other drugs, in light of a new case of hemorrhagic occlusive retinal vasculitis.News Alerts (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 3, 2017 Category: Consumer Health News Tags: Ophthalmology News Alert Source Type: news

Promising Therapies for Diabetic Eye Disease on the Way: Ophthalmology Times
(MedPage Today) -- Also, strategies for preventing tractional retinal detachment (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 3, 2017 Category: Cardiology Source Type: news

Rapid Ascent to High Altitude Alters the Retina Rapid Ascent to High Altitude Alters the Retina
Significant increases in retinal nerve fiber layer (RNFL) thickness occur after rapid ascent to a high-altitude environment and can lead to other pathological changes, researchers from China report.Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - October 3, 2017 Category: Opthalmology Tags: Ophthalmology News Source Type: news

New regulator of liver metabolism discovered
(Charit é - Universit ä tsmedizin Berlin) Researchers from Charit é - Universit ä tsmedizin Berlin have identified an enzyme that has a major effect on glucose utilization in liver cells. The enzyme, retinol saturase, helps these cells adapt to variations in glucose levels. However, when glucose levels are consistently too high, retinol saturase appears to exert a damaging effect on cells. Results from this study have been published in the journal Nature Communications*. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 29, 2017 Category: International Medicine & Public Health Source Type: news

Goodbye, login. Hello, heart scan.
(University at Buffalo) Forget fingerprint computer identification or retinal scanning. A University at Buffalo-led team has developed a computer security system using the dimensions of your heart as your identifier.The system uses low-level Doppler radar to measure your heart, and then continually monitors your heart to make sure no one else has stepped in to run your computer. The technology will be presented next month at the 23rd MobiCom conference. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2017 Category: International Medicine & Public Health Source Type: news

Goodbye, login. Hello, heart scan
(University at Buffalo) Forget fingerprint computer identification or retinal scanning. A University at Buffalo-led team has developed a computer security system using the dimensions of your heart as your identifier.The system uses low-level Doppler radar to measure your heart, and then continually monitors your heart to make sure no one else has stepped in to run your computer. The technology will be presented next month at the 23rd MobiCom conference. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2017 Category: International Medicine & Public Health Source Type: news

Artificial Intelligence May Transform Retinal Screening Artificial Intelligence May Transform Retinal Screening
The new technology is a potential breakthrough for diabetic retinopathy screening, but is not without risks.Medscape Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 18, 2017 Category: Consumer Health News Tags: Ophthalmology Commentary Source Type: news

Retinal surgeon expands practice while serving Native American communities and third-world countries
Retinal surgeon expands practice. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - September 18, 2017 Category: American Health Authors: Angela Gonzales Source Type: news

Ganglion Cell Loss May Trigger Retinal Problems in Congenital Zika Syndrome Ganglion Cell Loss May Trigger Retinal Problems in Congenital Zika Syndrome
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 14, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news

The effect of vitamin A on fracture risk: a meta-analysis of cohort studies - Zhang X, Zhang R, Moore JB, Wang Y, Yan H, Wu Y, Tan A, Fu J, Shen Z, Qin G, Li R, Chen G.
This meta-analysis evaluated the influence of dietary intake and blood level of vitamin A (total vitamin A, retinol or β-carotene) on total and hip fracture risk. Cohort studies published before July 2017 were selected through English-language literature ... (Source: SafetyLit)
Source: SafetyLit - September 14, 2017 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Eye changes may signal frontotemporal lobe degeneration
(University of Pennsylvania School of Medicine) Frontotemporal degeneration (FTD) is a progressive neurodegenerative condition that is present in tens of thousands of Americans, but is often difficult to diagnose accurately. Now in a study published this week online ahead of print in Neurology, researchers from the Perelman School of Medicine at the University of Pennsylvania have found evidence that a simple eye exam and retinal imaging test may help improve that accuracy. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - September 8, 2017 Category: International Medicine & Public Health Source Type: news

Google ’ s Verily is developing AI-powered heart disease test using retinal images
Google (NSDQ:GOOG) parent Alphabet‘s (NSDQ:GOOGL) Verily is developing a new artificial-intelligence powered test that searches for indicators of heart disease risk present in retina images, according to a new study. The study, which has not yet been peer reviewed but has been published by Cornell University, details a new machine-learning powered system designed by Verily to “discover new knowledge from retinal fundus images.” The system operates on data from 284,335 patients, validated on 2 independent datasets of 12,026 and 999 patients, to predict cardiovascular risks “not previously t...
Source: Mass Device - September 5, 2017 Category: Medical Devices Authors: Fink Densford Tags: Cardiovascular Imaging Optical/Ophthalmic Research & Development Alphabet Inc. Google Inc. Verily Source Type: news

Prevent vitamin A and iron deficiency - multivitamins ARE better than diet alone
MULTIVITAMINS are better than diet alone in preventing vitamin and mineral deficiency - a new study has found. (Source: Daily Express - Health)
Source: Daily Express - Health - August 31, 2017 Category: Consumer Health News Source Type: news

FDA approved "Bionic Man" retinal implant to treat certain types of blindness... but there's no spy vision capability (yet)
(Natural News) The FDA has just granted approval to Second Sight Medical Products to embark on a human clinical study of its newest visual prosthesis system. Known as Orion, the device is a newer iteration of the Sylmar, California-based company’s successful Argus II retinal implant product. The Argus II gained approval in 2013, and it... (Source: NaturalNews.com)
Source: NaturalNews.com - August 30, 2017 Category: Consumer Health News Source Type: news

Retinal Imaging Device May Offer Insight Into Alzheimer's Retinal Imaging Device May Offer Insight Into Alzheimer's
A noninvasive retinal imaging device that detects changes in the eye that are indicative of brain amyloid may provide new insight into Alzheimer's disease.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 30, 2017 Category: Consumer Health News Tags: Psychiatry News Source Type: news

FDA clears Second Sight IDE trial of next-gen Orion cortical visual prosthesis
Second Sight Medical (NSDQ:EYES) said today it won FDA investigational device exemption to initiate a feasibility clinical study of its Orion cortical visual prosthesis system. The conditional approval gives the Sylmar, Calif.-based company clearance to enroll up to 5 patients at 2 US sites, but requires that the company conduct additional device testing and “address outstanding questions” within 45 days, it said. “This is an exciting milestone for the company given the potential of Orion to provide useful vision to millions of blind individuals worldwide who have no other option today. We are deligh...
Source: Mass Device - August 28, 2017 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Food & Drug Administration (FDA) Optical/Ophthalmic Prosthetics second-sight-medical Source Type: news

Researchers unlock regenerative potential of cells in the mouse retina
(NIH/National Eye Institute) Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows. The findings potentially open the door to new treatments for eye trauma and retinal disease. The study appears in the July 26 issue of Nature, and was funded in part by the National Eye Institute, part of the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 28, 2017 Category: International Medicine & Public Health Source Type: news

New retinal imaging tech promises to help diagnose Alzheimers
New technology, developed by NeuroVision Imaging and Cedars-Sinai, is exploring the use of noninvasive eye imaging to detect Alzheimers disease, scanning the retina to identify protein deposits associated with the disorder. The system is designed to look for neurotoxic beta-amyloid protein deposits, which are also found in the brain in Alzheimers patients. Normally, such deposits are found through the use of positron emission tomography, or through the analysis of cerebrospinal fluid, both of which are invasive and costly, researchers said. Read the whole story on our sister site, Medical Design & Outsourcing The post ...
Source: Mass Device - August 23, 2017 Category: Medical Devices Authors: Fink Densford Tags: Diagnostics Imaging Research & Development NeuroVision Source Type: news

Retinal imaging may spot Alzheimer's disease early
Researchers from optical imaging technology firm NeuroVision Imaging and Cedars-Sinai...Read more on AuntMinnie.comRelated Reading: Retinal imaging device may detect early Alzheimer's (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - August 22, 2017 Category: Radiology Source Type: news

Clinical study shows that retinal imaging may detect signs of Alzheimer's disease
(Public Relations Pacific LLC) A study led by researchers at Cedars-Sinai and NeuroVision Imaging LLC provides the scientific basis for using noninvasive eye imaging to detect the pathological hallmarks of Alzheimer's. The experimental technology, developed by Cedars-Sinai and NeuroVision, scans the retina using techniques that can identify beta-amyloid protein deposits that mirror those in the brain. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 22, 2017 Category: International Medicine & Public Health Source Type: news

Noninvasive retinal imaging may improve early detection of Alzheimer's disease
(JCI Journals) In this issue of JCI Insight, researchers at Cedars-Sinai Medical Center adapted a noninvasive retinal imaging approach to characterize amyloid-β deposition, the pathological hallmark of Alzheimer's disease, in the retinas of patients and healthy controls. This imaging enabled detection and quantification of amyloid-β, revealing increased deposits in Alzheimer's patients compared to controls. These results demonstrate the feasibility of this approach as a tool for earlier Alzheimer's diagnosis and intervention. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - August 17, 2017 Category: International Medicine & Public Health Source Type: news