Dosing Adjuvant Chemo in Breast Cancer: Focus on Obesity Dosing Adjuvant Chemo in Breast Cancer: Focus on Obesity
Chemotherapy overdose may be avoided in obese patients with breast cancer using a tailored dosing strategy.Annals of Oncology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 18, 2019 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Complex Interrelationship Between Prescription and Illicit Opioids in Overdose Epidemic
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - March 17, 2019 Category: Orthopaedics Tags: Best of the Rest Source Type: news

Opioid Overdose Reversal News: FDA-approved naloxone devices produce substantially higher blood levels of naloxone than improvised nasal spray
Naloxone is a potentially life-saving drug commonly used to reverse opioid overdoses and can be injected as a liquid or delivered as a nasal spray. The fastest method of delivery is through an intravenous (IV) dose, but many first responders, police, families or friends are not well equipped... (Source: NIDA News)
Source: NIDA News - March 15, 2019 Category: Addiction Tags: Fentanyl, Health and Medical Professionals, NIDAMED News, Opioids, Pain Medication, Researchers Source Type: news

OxyContin's maker is accused of fueling the opioid epidemic. Its new overdose antidote was just fast-tracked by the FDA
The US Food and Drug Administration granted Purdue Pharma's experimental opioid overdose drug fast-track designation. According to Purdue, its drug, nalmefene hydrochloride injection, has a longer effect than naloxone, another opioid antagonist that is approved to reverse overdoses. (Source: CNN.com - Health)
Source: CNN.com - Health - March 14, 2019 Category: Consumer Health News Source Type: news

Trusting the source: the potential role of drug dealers in reducing drug-related harms via drug checking - Bardwell G, Boyd J, Arredondo J, McNeil R, Kerr T.
We examined the level of trust people who use drugs (PWUD) have in their drug dealers as well as their perspectives on the potential ... (Source: SafetyLit)
Source: SafetyLit - March 14, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Doctors Are Writing Half as Many New Opioid Prescriptions as They Used To, Study Says
Deaths from opioid overdoses have increased dramatically over the last decade. In 2017, the latest year for which the U.S. government has statistics on the trend, more than 47,000 Americans died of opioid overdoses. One major factor contributing to the rising number of people who get addicted to opioids and die from overdoses is the increasing number of prescriptions written by doctors to treat pain. Overdose deaths related to such prescriptions increased five times from 1999 to 2017. But according to the latest study looking at opioid prescribing patterns, published in the New England Journal of Medicine, recent efforts t...
Source: TIME: Health - March 13, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs Source Type: news

Hospital reviews 48 nurses, pharmacists over dosages, deaths
The Ohio hospital system where an intensive-care doctor is accused of ordering painkiller overdoses for dozens of patients says it has put more employees on leave and changed key leaders at the hospital where nearly all those deaths occurred (Source: ABC News: Health)
Source: ABC News: Health - March 13, 2019 Category: Consumer Health News Tags: Health Source Type: news

OxyContin maker gets fast track approval for opioid overdose drug
(Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 13, 2019 Category: Pharmaceuticals Source Type: news

OxyContin maker makes progress on overdose drug
Purdue Pharma says FDA will expedite approval process for its not-for-profit injection (Source: FT.com - Drugs and Healthcare)
Source: FT.com - Drugs and Healthcare - March 13, 2019 Category: Pharmaceuticals Source Type: news

Many Heroin Users Unprepared for Fentanyl OD
TUESDAY, March 12, 2019 -- Though they know that nearly all heroin is laced with the dangerous synthetic opioid fentanyl, many Baltimore users aren't prepared to prevent or treat fentanyl-related overdoses, a new study finds. Baltimore has a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 12, 2019 Category: General Medicine Source Type: news

Vets Who Get Opioids From VA, Medicare at Higher Overdose Risk
Title: Vets Who Get Opioids From VA, Medicare at Higher Overdose RiskCategory: Health NewsCreated: 3/11/2019 12:00:00 AMLast Editorial Review: 3/12/2019 12:00:00 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 12, 2019 Category: Anesthesiology Source Type: news

Dual Receipt of Opioids Tied to Increased Risk for OD Death
Those enrolled in both VA and Medicare Part D have higher odds of death from Rx opioid overdose (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - March 12, 2019 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

Dual Receipt of Opioids Tied to Increased Risk for OD Death
MONDAY, March 11, 2019 -- For veterans enrolled in the U.S. Department of Veterans Affairs (VA) and Medicare Part D, receipt of opioids from both VA and Part D is associated with an increased likelihood of death from prescription opioid overdose,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 11, 2019 Category: Pharmaceuticals Source Type: news

Vets Who Get Opioids From VA, Medicare at Higher Overdose Risk
MONDAY, March 11, 2019 -- Many military veterans can get prescription opioid painkillers from both the VA and Medicare, putting them at nearly triple the risk for an overdose, new research warns. The finding could have implications for a huge... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 11, 2019 Category: General Medicine Source Type: news

Acetaminophen hepatotoxicity - Ramachandran A, Jaeschke H.
Acetaminophen (APAP) is one of the most popular and safe pain medications worldwide. However, due to its wide availability, it is frequently implicated in intentional or unintentional overdoses where it can cause severe liver injury and even acute liver fa... (Source: SafetyLit)
Source: SafetyLit - March 11, 2019 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Ansell Introduces Nitrile Glove for Enhanced Fentanyl Protection
ISELIN, NJ - Ansell, a global leader in safety solutions, announces the launch of MICROFLEXMidKnight XTRA, a nitrile exam glove that has been tested against both fentanyl and gastric acid to simulate real-world overdose situations. The glove features an elongated cuff for added coverage of the wrist and forearm and has a distinctive black color that allows wearers to easily see potentially hazardous powders on hands.  Fentanyl is a synthetic opioid up to 50 times more potent than heroin. In fact, a recent study from the National Safety Council shows the odds of dying from accidental opioid overdose in the U.S. now sur...
Source: JEMS Operations - March 11, 2019 Category: Emergency Medicine Authors: Ansell (press release) Tags: Press Releases Operations Source Type: news

OxyContin maker Purdue Pharma loses bid to delay opioid epidemic trial
OxyContin maker Purdue Pharma LP and two other drugmakers on Friday lost a bid to delay a landmark trial set for May in a multibillion-dollar lawsuit by Oklahoma's attorney general accusing them of helping fuel an opioid abuse and overdose epidemic in the state. (Source: Reuters: Health)
Source: Reuters: Health - March 9, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Supporting providers after drug overdose death - Yule AM, Levin FR.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - March 5, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Heroin users aware of fentanyl, but at high risk of overdosing
(Johns Hopkins University Bloomberg School of Public Health) Most heroin users in Baltimore, a city heavily affected by the opioid epidemic, recognize that the heroin they buy is now almost always laced with the highly dangerous synthetic opioid fentanyl, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 5, 2019 Category: International Medicine & Public Health Source Type: news

BTG shareholders OK $4B Boston Scientific buyout
BTG (LON:BTG) said yesterday that its shareholders voted to approve a more than $4 billion buyout offer by Boston Scientific (NYSE:BSX) and affirmed that the deal is on track to close mid-year. The British medical device maker said that some 95.4% of the shareholders affected by the tie-up voted for the deal, with 4.6% of those shares voting against. Overall, the votes to approve the merger amounted to 62.4% of total BTG shares and the votes against were 0.03%, BTG said. Earlier this week Marlborough, Mass.-based Boston Scientific said it closed a $4.3 billion debt round it plans use to defray the ...
Source: Mass Device - March 1, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Featured Mergers & Acquisitions Wall Street Beat Boston Scientific BTG Source Type: news

Coma and seizure caused by an afloqualone overdose - Kitami Y, Takei H, Nagai Y, Fujita K, Miyama S.
Afloqualone, an analogue of methaqualone developed in the 1980s in Japan,1, 2 is a centrally acting muscle relaxant that affects the spinal polysynaptic reflexes and is used by patients with cervico ‐omobrachial syndrome, lumbar pain, and spastic paral... (Source: SafetyLit)
Source: SafetyLit - March 1, 2019 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

EMS Medical Directors Chart the Future of EMS at Annual Gathering of Eagles
The Metropolitan Medical Directors Coalition (AKA “Eagles”) 21st Annual Retreat (AKA “Eagle Creek”) was held Wednesday and Thursday, February 27 and 28, at the Dallas Sheraton Hotel under the leadership of Paul Pepe, MD. The closed, invitation-only retreat is attended by 70 medical directors from the most-populated metropolitan EMS systems as well as 18 EMS fellows—33% of the nation’s current EMS fellows. This group oversees EMS for a combined population of over 114 million people in the United States and abroad, with representatives from Canada; Germany; New Zealand; Italy; Amsterdam, T...
Source: JEMS Patient Care - February 28, 2019 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT P Tags: Top Story News Exclusive Articles Patient Care Administration and Leadership Operations Source Type: news

EMS Medical Directors Chart the Future of EMS at Annual Gathering of Eagles
The Metropolitan Medical Directors Coalition (AKA “Eagles”) 21st Annual Retreat (AKA “Eagle Creek”) was held Wednesday and Thursday, February 27 and 28, at the Dallas Sheraton Hotel under the leadership of Paul Pepe, MD. The closed, invitation-only retreat is attended by 70 medical directors from the most-populated metropolitan EMS systems as well as 18 EMS fellows—33% of the nation’s current EMS fellows. This group oversees EMS for a combined population of over 114 million people in the United States and abroad, with representatives from Canada; Germany; New Zealand; Italy; Amsterdam, T...
Source: JEMS Administration and Leadership - February 28, 2019 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT P Tags: Top Story News Exclusive Articles Patient Care Administration and Leadership Operations Source Type: news

EMS Medical Directors Chart the Future of EMS at Annual Gathering of Eagles
The Metropolitan Medical Directors Coalition (AKA “Eagles”) 21st Annual Retreat (AKA “Eagle Creek”) was held Wednesday and Thursday, February 27 and 28, at the Dallas Sheraton Hotel under the leadership of Paul Pepe, MD. The closed, invitation-only retreat is attended by 70 medical directors from the most-populated metropolitan EMS systems as well as 18 EMS fellows—33% of the nation’s current EMS fellows. This group oversees EMS for a combined population of over 114 million people in the United States and abroad, with representatives from Canada; Germany; New Zealand; Italy; Amsterdam, T...
Source: JEMS: Journal of Emergency Medical Services News - February 28, 2019 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT P Tags: Top Story News Exclusive Articles Patient Care Administration and Leadership Operations Source Type: news

EMS Medical Directors Chart the Future of EMS at Annual Gathering of Eagles
The Metropolitan Medical Directors Coalition (AKA “Eagles”) 21st Annual Retreat (AKA “Eagle Creek”) was held Wednesday and Thursday, February 27 and 28, at the Dallas Sheraton Hotel under the leadership of Paul Pepe, MD. The closed, invitation-only retreat is attended by 70 medical directors from the most-populated metropolitan EMS systems as well as 18 EMS fellows—33% of the nation’s current EMS fellows. This group oversees EMS for a combined population of over 114 million people in the United States and abroad, with representatives from Canada; Germany; New Zealand; Italy; Amsterdam, T...
Source: JEMS Operations - February 28, 2019 Category: Emergency Medicine Authors: A.J. Heightman, MPA, EMT P Tags: Top Story News Exclusive Articles Patient Care Administration and Leadership Operations Source Type: news

Viewpoint: Businesses must play role in fighting addiction epidemic
With 22 million Americans struggling with a substance use disorder and with more than five people dying every day in Massachusetts from an overdose, the opioid crisis is touching every part of society. Two recent studies commissioned by RIZE Massachusetts show how widespread the effect is on the Massachusetts workforce and economy. The Massachusetts Taxpayers Foundation estimates the cost at nearly $5 billion in lost productivity and increased health care spending. In a separate report, Brandeis … (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 28, 2019 Category: American Health Source Type: news

Research is imagining a world where painkillers are designed to keep people safe while alleviating discomfort: Looking at opioid overdose and respiratory depression
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - February 28, 2019 Category: Hospital Management Tags: Hospital News Source Type: news

The American life span gets shorter - Sofer D.
The data reflect more deaths from suicide and drug overdose. Language: en... (Source: SafetyLit)
Source: SafetyLit - February 27, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioids: A Surging Crisis in Rural America
Provides an overview of opioids and the opioid epidemic, with a focus on its impact on rural areas, farmers and farm workers, the Latino community, and the overlap between these groups. According to the Centers for Disease Control and Prevention (CDC), opioid overdoses in this community have risen by at least 52.5% since 2016. 74% of farm workers have been directly impacted by opioid abuse. (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - February 27, 2019 Category: Rural Health Source Type: news

Should drug dealers be charged with murder? States ponder
The opioid crisis is spurring many states to take a tougher stance against drug dealers, including creating laws that treat fatal overdoses as murders and manslaughters (Source: ABC News: Health)
Source: ABC News: Health - February 25, 2019 Category: Consumer Health News Tags: Health Source Type: news

Method of self-harm and risk of self-harm repetition: findings from a national self-harm registry - Cully G, Corcoran P, Leahy D, Griffin E, Dillon C, Cassidy E, Shiely F, Arensman E.
BACKGROUND: Risk of self-harm repetition has consistently been shown to be higher following self-cutting compared to intentional drug overdose (IDO) and other self-harm methods. The utility of previous evidence is limited due to the large heterogeneous met... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

A scoping review of harm reduction training for police officers - Khorasheh T, Naraine R, Watson TM, Wright A, Kallio N, Strike C.
ISSUES: Preventable overdose deaths, especially due to opioids, have increasingly been reported worldwide. Expansion of life-saving harm reduction services is underway with increasing public support in some jurisdictions. However, such services often fall ... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Fatal overdose with a combination of SNRIs venlafaxine and duloxetine - Alibegovi ć A, Kariž S, Volavšek M.
Drugs for the treatment of depressive disorders, including SNRIs (serotonin noradrenaline reuptake inhibitors) venlafaxine and duloxetine, are widely prescribed as they have a high therapeutic to toxicity ratio. In rare cases, adverse effects may be severe... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Increased overdose mortality during the first week of the month: revisiting the "check effect" through a spatial lens - Goedel WC, Green TC, Viner-Brown S, Rich JD, Marshall BDL.
BACKGROUND: The timing of social service benefit issuance is thought to be associated with increased drug overdose fatalities. However, the extent to which this excess mortality is concentrated in communities with higher levels of benefit receipt has not b... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Money, politics, and firearm safety: physician political action committees in the era of "This is our lane" - Cunningham RM, Zimmerman MA, Carter PM.
Firearm injuries are a significant US public health problem, responsible for nearly 40  000 deaths annually.1 In 2017, firearms surpassed motor vehicle crashes and are now second only to opioid and other drug-related overdoses as the leading cause of i... (Source: SafetyLit)
Source: SafetyLit - February 25, 2019 Category: International Medicine & Public Health Tags: Commentary Source Type: news

Fewer hospital programs address opioid abuse, Ohio University study finds
(Ohio University) The damage done to America's health by the opioid epidemic is well-recognized and enormous, with drug overdose death rates helping to drive down US life expectancy in recent years. Yet as the problem has worsened, American hospitals collectively have seen a loss of programs dealing with substance abuse. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 25, 2019 Category: International Medicine & Public Health Source Type: news

Spain Tops Italy as World ’s Healthiest Country While U.S. Falls: Report
Maybe it’s something in the gazpacho or paella, as Spain just surpassed Italy to become the world’s healthiest country. That’s according to the 2019 edition of the Bloomberg Healthiest Country Index, which ranks 169 economies according to factors that contribute to overall health. Spain placed sixth in the previous gauge, published in 2017. Four additional European nations were among the top 10 in 2019: Iceland (third place), Switzerland (fifth), Sweden (sixth) and Norway (ninth). Japan was the healthiest Asian nation, jumping three places from the 2017 survey into fourth and replacing Singapore, which dr...
Source: TIME: Health - February 24, 2019 Category: Consumer Health News Authors: Lee Miller and Wei Lu / Bloomberg Tags: Uncategorized onetime Spain Source Type: news

Hospital: 5 patients given overdoses may have been treatable
The Ohio hospital system investigating a doctor accused of ordering painkiller overdoses for dozens of patients says five who died may have received excessive doses when there still was a chance to improve their condition with treatment (Source: ABC News: Health)
Source: ABC News: Health - February 22, 2019 Category: Consumer Health News Tags: Health Source Type: news

Since Early 2000s, Overdose Death Rates Are Highest in U.S.
FRIDAY, Feb. 22, 2019 -- Since the early 2000s, the United States has had the highest drug overdose death rates among its peer countries, according to a study published online Feb. 21 in the Population and Development Review. Jessica Y. Ho, Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 22, 2019 Category: Pharmaceuticals Source Type: news

Narcan-maker Opiant abandons bulimia drug
Opiant Pharmaceuticals, a specialty pharmaceutical company developing medicines for addictions and drug overdose, has halted its trial for a nasal spray designed to treat bulimia nervosa. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - February 22, 2019 Category: Pharmaceuticals Source Type: news

ERs Often Miss Chance to Set Overdose Survivors on'Better Path'ERs Often Miss Chance to Set Overdose Survivors on'Better Path '
Fewer than 10% of nonfatal overdose patients in West Virginia ERs received follow-up care, study says. It's a scenario that plays out across the US.Kaiser Health News (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - February 22, 2019 Category: Emergency Medicine Tags: Emergency Medicine News Source Type: news

Opioid Overdose Deaths Quadruple, Centered in 8 States
FRIDAY, Feb. 22, 2019 -- U.S. opioid overdose deaths have quadrupled in the last two decades, and the highest rates are now seen in eight Eastern states, a new study shows. Those states are: Connecticut, Illinois, Indiana, Massachusetts, Maryland,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 22, 2019 Category: General Medicine Source Type: news

Opioid Overdose Deaths Quadruple, Centered in 8 States
This study also found that the highest rates at present are in eight Eastern states: Connecticut, Illinois, Indiana, Massachusetts, Maryland, Maine, New Hampshire, and Ohio. Additionally, it found a 26% increase in opioid overdose deaths among African Americans between 2016 and 2017, which is the largest increase among any racial group. (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - February 22, 2019 Category: Rural Health Source Type: news

U.S. Leads Rich Nations in Drug Overdose Deaths
Drug deaths in the United States are more than 27 times higher than in Italy and Japan, which have the lowest rates, and are double the rates of Finland and Sweden, the countries with the next highest death rates. (Source: WebMD Health)
Source: WebMD Health - February 21, 2019 Category: Consumer Health News Source Type: news

U.S. overdose deaths highest among wealthy nations, study says
Drug addiction has taken many lives globally, but it's had a disproportionate impact on life expectancy in the United States, a new study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - February 21, 2019 Category: Consumer Health News Source Type: news

Among Rich Nations, U.S. Has Highest Rate of Fatal Drug ODs
THURSDAY, Feb. 21, 2019 -- It's a ranking that no country would want to have: A new study shows America has taken the lead in drug overdose deaths, with rates almost four times higher than in 17 other wealthy nations. Drug overdose deaths in the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 21, 2019 Category: General Medicine Source Type: news

More States Say Doctors Must Offer Overdose Reversal Drug Along With Opioids
Discusses new state laws and regulations in several states aiming to reduce opioid overdoses. Patients who are receiving a large dosage of an opioid, who take certain other drugs, who have sleep apnea, or who have a history of addiction are considered to have a higher risk of overdosing. For these patients, these states require physicians to either prescribe naloxone alongside the opioid or to at least offer it to the patient. (Source: News stories via the Rural Assistance Center)
Source: News stories via the Rural Assistance Center - February 21, 2019 Category: Rural Health Source Type: news

American drug overdose death rates the highest among wealthy nations, USC study finds
(University of Southern California) A USC study found that the United States has the highest drug overdose death rates among a set of high-income countries. The study found that drug overdose death rates in the United States are 3.5 times higher on average when compared to 17 other high-income counties. The study is the first to demonstrate that the drug overdose epidemic is contributing to the widening gap in life expectancy between the United States and other high-income countries. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 21, 2019 Category: International Medicine & Public Health Source Type: news

Is the drug overdose epidemic unique to the United States?
(Wiley) Is the current American drug overdose epidemic an isolated phenomenon? Have other high-income countries experienced similar increases in drug overdose mortality, or are they likely to going forward? A new study published in Population and Development Review addresses these questions. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 21, 2019 Category: International Medicine & Public Health Source Type: news

'When I'm around my people, I feel safe': City aims to combat Indigenous overdoses amid opioid crisis
A new strategy released by Toronto Public Health targets Indigenous communities, calls for culturally safe medical care, Indigenous-led consumption sites and support services. (Source: CBC | Health)
Source: CBC | Health - February 20, 2019 Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news