FDA OKs New High-Dose Naloxone Product for Opioid Overdose FDA OKs New High-Dose Naloxone Product for Opioid Overdose
ZIMHI from Adamis Pharmaceuticals is administered using a single-dose, prefilled syringe that delivers 5 mg of naloxone hydrochloride solution through intramuscular or subcutaneous injection.FDA Approvals (Source: Medscape Emergency Medicine Headlines)
Source: Medscape Emergency Medicine Headlines - October 19, 2021 Category: Emergency Medicine Tags: Psychiatry News Alert Source Type: news

FDA approves naloxone injection to counteract opioid overdoses
FDA approves ZIMHI (naloxone hydrochloride) injection as an additional option to treat opioid overdose. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 18, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Comparing mortality from CoViD-19 to mortality due to overdose: a micromort analysis - Lee Y, Lui LMW, Brietzke E, Liao Y, Lu C, Ho R, Subramaniapillai M, Mansur RB, Rosenblat JD, McIntyre RS.
OBJECTIVE: To compare the mortality risk due to covid-19 with death due to overdose in British Columbia, Canada. The opioid epidemic was declared a public health emergency in 2016. METHODS: Mortality risk was calculated in micromorts with covid-19 ... (Source: SafetyLit)
Source: SafetyLit - October 18, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Decision tree outcome prediction of acute acetaminophen exposure in the United States: a study of 30,000 cases from the National Poison Data System - Mehrpour O, Saeedi F, Hoyte C.
Acetaminophen is one of the most commonly used analgesic drugs in the United States. However, the outcomes of acute acetaminophen overdose might be very serious in some cases. Therefore, prediction of the outcomes of acute acetaminophen exposure is crucial... (Source: SafetyLit)
Source: SafetyLit - October 18, 2021 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Racial/ethnic differences in ED opioid prescriptions for long bone fractures: trends over time - Goyal MK, Drendel AL, Chamberlain JM, Wheeler J, Olsen C, Grundmeier RW, Cook L, Bajaj L, Babcock L, Zorc JJ, Johnson T, Alpern ER.
Pain caused by long bone fractures is a common reason for opioid prescribing in the emergency department (ED) setting.1 Approximately 40% of opioid overdose deaths involve a prescription,2 and in response, opioid prescribing has declined in the last dec... (Source: SafetyLit)
Source: SafetyLit - October 16, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

CDC Reports Record High 12 - Month Drug Overdose Death Toll
Record - high 96,779 drug overdose deaths reported from March 2020 to March 2021 (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 15, 2021 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Institutional, Source Type: news

CDC Reports Record High 12-Month Drug Overdose Death Toll
A record high 96,779 drug overdose deaths occurred between March 2020 and March 2021, representing a 29.6% rise (Source: WebMD Health)
Source: WebMD Health - October 14, 2021 Category: Consumer Health News Source Type: news

US Supreme Court won't hear dispute over injection sites
The U.S. Supreme Court won’t review a nonprofit group’s effort to open a supervised injection site in Philadelphia to try to reduce overdose deaths (Source: ABC News: Health)
Source: ABC News: Health - October 13, 2021 Category: Consumer Health News Tags: Health Source Type: news

Drug overdose deaths in US reached record-high of 96,000 during the first 12 months of the pandemic
Between March 2020 and March 2021, the U.S. recorded a record-high 96,779 drug overdose deaths, new CDC data show, a 29.5% increase from 74,679 recorded over the previous 12 months. (Source: the Mail online | Health)
Source: the Mail online | Health - October 13, 2021 Category: Consumer Health News Source Type: news

Addressing drug overdose deaths in pediatrics: where do we go from here? - Renny MH, Cerd á M.
Drug overdose deaths continue to rise in the USA. The majority of drug overdose deaths are in adults, and therefore, studies investigating overdose mortality rates in young children are limited. Despite smaller numbers, these deaths must not be overlooked.... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Association between opioid overdose death rates and educational attainment - United States, 2010-2019 - Duan WR, Hand DJ.
Educational attainment may be an indicator of disparities in the ongoing opioid-overdose crisis. To understand the association between educational attainment and fatal opioid overdose, death records in the mortality files published by the Centers for Disea... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Enacting fentanyl tests strips for overdose prevention: the socio-material transformation of "suspect technologies" into "technologies of solidarity" - Campbell ND.
This article places FTS within the historical contexts of drug-checking for drug control, overdose prevention, and harm reduc... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Evaluation of factors related to overdose in patients with impaired consciousness who are transported by emergency medical services: an age-specific research - Nagashima K, Sumida M, Imanaka S, Kuwabara T, Kaneko I, Miyake Y, Yasuno N, Itagaki F, Watanabe M.
BACKGROUND: Drug overdose accounts for most of the admissions to the emergency department. Prescription drugs, most of which are psychotropic medications, are often misused for drug overdose. The purpose of this study was to investigate the association bet... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Fatal opioid overdoses during and shortly after hospital admissions in England: a case-crossover study - Lewer D, Eastwood B, White M, Brothers TD, McCusker M, Copeland C, Farrell M, Petersen I.
BACKGROUND: Hospital patients who use illicit opioids such as heroin may use drugs during an admission or leave the hospital in order to use drugs. There have been reports of patients found dead from drug poisoning on the hospital premises or shortly after... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Framing public health response to the opioid and overdose crisis: are there alternatives to cascade of care model? - H øj SB, Bruneau J, Hickman M.
The 'cascade of care' has seen widespread uptake as a framework for measuring patient engagement in care for chronic conditions including HIV, hepatitis C and diabetes.1 Attention recently turned to its potential utility in the field of addiction care, par... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Lay knowledge and practices of methamphetamine use to manage opioid-related overdose risks - Daniulaityte R, Silverstein SM, Getz K, Juhascik M, McElhinny M, Dudley S.
AIM: Methamphetamine use has increased among individuals with opioid use disorder. The key aims of this study are to detail and contextualise lay knowledge, attitudes, and behaviours related to methamphetamine use in relation to opioid overdose risks in an... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Moving beyond Narcan: a police, social service, and researcher collaborative response to the opioid crisis - White MD, Perrone D, Watts S, Malm A.
The opioid crisis is the most persistent, long-term public health emergency facing the United States, and available evidence suggests the crisis has worsened during the COVID-19 global pandemic. Naloxone is an effective overdose response that saves lives, ... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioid poisoning cases aged 50+ in the 2015-2020 National Poisoning Data System: suspected suicides versus unintentional poisoning and other intentional misuse/abuse - Choi NG, Choi BY, Dinitto DM, Marti CN, Baker SD.
High rates of opioid overdose and suicide among the 50+ age group call for an examination of suicidal intent in overdose incidents. Using 2015-2020 National Poison Data System opioid poisoning cases aged 50+ (n  = 83 153), we examined the types of opioi... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Paracetamol toxicity in mild overdose in combination with opioids: a retrospective observational study - Amer H, Archer JRH, Layne K, Dines AM, Wood DM, Greene SL, Dargan PI.
AIMS Toxicity in paracetamol overdose with opioid co-ingestion is poorly understood. We compared outcomes in both paracetamol-only and paracetamol-opioid overdoses to determine whether toxicity differed significantly between the groups, and to assess the u... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Pharmacokinetics of loxoprofen in a self-administered overdose in a Japanese patient admitted to hospital - Adachi K, Sugitani Y, Unita R, Yoshida K, Beppu S, Terashima M, Fujii M, Shimizu M, Yamazaki H.
Loxoprofen is a propionic acid derivative and is the most widely prescribed non-steroidal anti-inflammatory drug in Japan. Loxoprofen is generally considered to be relatively nontoxic. Case presentation A 33-year-old man (body weight, 55 kg) who i... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The New York City Prescriber Notification Program: assessing the feasibility of a patient overdose death notification pilot - LaSane K, Allen B, Liebman E, Paone D.
Opioid analgesics and benzodiazepines remain substantial contributors to unintentional drug overdose deaths in the United States. To promote judicious prescribing and improve care for patients with substance use disorders, the New York City Department of H... (Source: SafetyLit)
Source: SafetyLit - October 11, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Hospital Discharge Tied to Higher Risk for Opioid - Related Deaths
Fatal opioid overdoses four times more likely in the two days after hospital discharge (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - October 7, 2021 Category: Psychiatry Tags: Pharmacy, Psychiatry, Journal, Source Type: news

Meth overdose deaths in the U.S. almost tripled from 2015 to 2019
Data show that such fatalities rose from 5,526 to 15,489 in that period, researchers say in a study. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - October 2, 2021 Category: Consumer Health News Authors: Erin Blakemore Source Type: news

Socioeconomic correlates of incident and fatal opioid overdose among Swedish people with opioid use disorder - Dahlman D, Ohlsson H, Edwards AC, Sundquist J, H åkansson A, Sundquist K.
In this study, we assessed socioeconomic and other factors ... (Source: SafetyLit)
Source: SafetyLit - September 30, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Rethinking What it Means to Recover from Addiction
When I kicked cocaine and heroin in 1988, I was told that there was only one way to get better: abstain forever from psychoactive substances including alcohol—and practice the 12 steps made famous by Alcoholics Anonymous. The only alternative, counselors and group members said, was “jails, institutions or death.” My addiction was so extreme that by the end, I was injecting dozens of times a day. So I grabbed the lifeline I was thrown and attended the traditional 12-step rehab program recommended by the hospital where I underwent withdrawal. But once I began to study the scientific data on addiction, I lea...
Source: TIME: Health - September 29, 2021 Category: Consumer Health News Authors: Maia Szalavitz Tags: Uncategorized Source Type: news

Drug decriminalization movement gaining momentum in Canada as overdose deaths surge
As overdose deaths keep surging in Canada, the movement to decriminalize illicit drugs is gaining steam, with one of the country’s largest mental health facilities joining national advocates and several major cities in pressuring Ottawa to act. (Source: CBC | Health)
Source: CBC | Health - September 29, 2021 Category: Consumer Health News Tags: News/Health Source Type: news

Vitamin D supplement warning: Overdose side effects explained - and the exact amount you s
VITAMIN D deficiency is very common in the UK, particularly during the winter months. While vitamin D deficiency can have serious effects on your health, so can taking too much vitamin D. What are the side effects of too much vitamin D? (Source: Daily Express - Health)
Source: Daily Express - Health - September 28, 2021 Category: Consumer Health News Source Type: news

Inconsistencies in overdose suicide death investigation practice and potential remedies using technology: a Centers for Disease Control and Prevention Consultation meeting summary - Mercado MC, Stone DM, Kokubun CW, Trudeau ART, Gaylor E, Holland KM, Bartholow BN.
INTRODUCTION: It is widely accepted that suicides-which account for more than 47 500 deaths per year in the United States-are undercounted by 10% to 30%, partially due to incomplete death scene investigations (DSI) and varying burden-of-proof standards acr... (Source: SafetyLit)
Source: SafetyLit - September 28, 2021 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

The Wire" actor Michael K. Williams died of an accidental overdose, medical examiner says
Michael K. Williams was found dead at his Brooklyn home earlier this month. (Source: Reuters: Health)
Source: Reuters: Health - September 25, 2021 Category: Consumer Health News Source Type: news

Massive 'horse' lies about Nobel prize winning treatment
STORY AT-A-GLANCE KFOR news ran a fake story in which a doctor claimed emergency rooms in Oklahoma were inundated with people who used horse ivermectin paste as a treatment for COVID-19 and overdosed The story turned out to be pure fiction, as no such cases have occurred. Still, KFOR has not retracted the story or... (Source: NaturalNews.com)
Source: NaturalNews.com - September 25, 2021 Category: Consumer Health News Source Type: news

Actor Michael K Williams died of accidental drug overdose, coroner confirms
The actor died after overdosing on a combination of fentanyl, p-fluorofentanyl, heroin and cocaine. (Source: Reuters: Health)
Source: Reuters: Health - September 25, 2021 Category: Consumer Health News Source Type: news

Michael K Williams died from overdose of fentanyl, heroin and other drugs, medical examiner says
Death of actor known for The Wire and Lovecraft Country was ruled an accident (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

Michael K. Williams died of an accidental overdose, medical examiner determines
Actor Michael K. Williams died from "acute intoxication by the combined effects of fentanyl, p-fluorofentanyl, heroin and cocaine," the... (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

Michael K. Williams died from accidental overdose, says New York medical examiner
Williams overdosed from a combination of "fentanyl, p-fluorofentanyl, heroin and cocaine." (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

Michael K. Williams' Cause of Death Was a Drug Overdose, Authorities Say
The actor known for “The Wire,” who was found dead in his apartment earlier this month, died of intoxication by a mixture of heroin,... (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

Michael K. Williams' cause of death revealed by medical examiner
The New York City medical examiner confirmed actor Michael K. Williams died of an overdose, The Post confirmed on Friday. His death was... (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

Michael K. Williams' Death Ruled Accidental OD Involving Fentanyl and Heroin
Michael K. Williams' cause of death is a drug overdose involving fentanyl, heroin and cocaine. (Source: Reuters: Health)
Source: Reuters: Health - September 24, 2021 Category: Consumer Health News Source Type: news

U.S. Meth Overdose Deaths Tripled in Recent Years
While the number of methamphetamine users did not increase as steeply, researchers said frequent use of methamphetamine, and using other drugs at the same time, may have contributed to the increase in overdose deaths. (Source: WebMD Health)
Source: WebMD Health - September 23, 2021 Category: Consumer Health News Source Type: news

An examination of fatal child poisonings in the United States using the National Violent Death Reporting System (NVDRS), 2012-2017 - Hunter AA, Schwab-Reese L, DiVietro S, McCollum S.
BACKGROUND: Fatal drug overdoses are predominantly attributed to opioids. Women of childbearing age are among those at greatest risk, underscoring the need to understand the overlapping risk of fatal poisoning in children. METHODS: A retrospective ... (Source: SafetyLit)
Source: SafetyLit - September 23, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Methamphetamine-involved overdose deaths nearly tripled between 2015 to 2019, NIH study finds
Patterns of methamphetamine use have become riskier, diversified across U.S. population. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - September 22, 2021 Category: American Health Source Type: news

U.S. stimulant deaths nearly triple in four-year period, mostly because of methamphetamine
Drug overdose deaths linked with illegal stimulants other than cocaine -- mostly methamphetamine -- nearly tripled between 2015 and 2019, an analysis published Wednesday by JAMA Psychiatry found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 22, 2021 Category: Consumer Health News Source Type: news

Methamphetamine Deaths Soar, Hitting Black And Native Americans Especially Hard
Newly published U.S. data finds overdose deaths from methamphetamine use more than doubled in recent years. Use of the stimulant among Black Americans surged nearly tenfold.(Image credit: Tulare County Sheriff's Office via AP) (Source: NPR Health and Science)
Source: NPR Health and Science - September 22, 2021 Category: Consumer Health News Authors: Brian Mann Source Type: news

Which illicit drugs are injected in Oslo? A study based on analysis of drug residues in used injection equipment and self-reported information - Gjerde H, Bretteville-Jensen AL, Bache-Andreassen L, Hanoa K, Furuhaugen H, Brochmann GW, Vindenes V.
BACKGROUND: People who inject drugs (PWID) have a high risk of premature death due to fatal overdoses. Newly emerged fentanyls, much more potent than heroin and other opioids, may increase this risk further. Therefore, precise information on injected drugs... (Source: SafetyLit)
Source: SafetyLit - September 22, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Methamphetamine-involved overdose deaths nearly tripled between 2015 to 2019, NIH study finds
Patterns of methamphetamine use have become riskier, diversified across U.S. population (Source: NIDA News)
Source: NIDA News - September 22, 2021 Category: Addiction Tags: Cocaine, News Release, Fentanyl, Heroin, Methamphetamine, Overdose, Researchers Source Type: news

Las muertes por sobredosis relacionadas con la metanfetamina casi se triplicaron entre 2015 y 2019, de acuerdo con un estudio de los NIH
(Source: NIDA News)
Source: NIDA News - September 22, 2021 Category: Addiction Tags: Cocaine, News Release, Fentanyl, Heroin, Methamphetamine, Overdose, Researchers Source Type: news

Animal Sedative Is Driving Rise in Fatal Drug ODs
According to a new CDC report, xylazine has turned up in overdose deaths in 25 of 38 states examined and in 2019, it contributed to death in 64% of cases and almost always also involved fentanyl. (Source: WebMD Health)
Source: WebMD Health - September 21, 2021 Category: Consumer Health News Source Type: news

< a href= " /news-events/nih-research-matters/opioid-overdose-deaths-rise-among-black-americans " > Opioid overdose deaths rise among Black Americans < /a >
While opioid overdose deaths remained flat overall between 2018 and 2019, they rose sharply for Black Americans. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - September 21, 2021 Category: Consumer Health News Source Type: news

Opioid Overdose Death Rates Worsening for Non - Hispanic Blacks
No significant change seen in overdose death rates overall from 2018 to 2019, but rate increased among non - Hispanic Blacks (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - September 20, 2021 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Anesthesiology & amp; Pain, Journal, Source Type: news

When fentanyl finds an outlier: talking with teenagers about the danger - Cook-Sather SD, Urban E, Romano VA, Romano MA.
In the United States from 2013 to 2019, the nonmethadone synthetic opioid-involved death rate increased 1040%, from 1.0 to 11.4 per 100  000 (age adjusted), with 51.5% of all 2019 drug overdose deaths linked to synthetic opioids such as fentanyl.1 Opioid-... (Source: SafetyLit)
Source: SafetyLit - September 20, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Characterizing opioid-involved overdose risk in local communities: an opioid overdose vulnerability assessment across Indiana, 2017 - Sawyer JL, Shrestha S, Pustz JC, Gottlieb R, Nichols D, Van Handel M, Lingwall C, Stopka TJ.
The objective of this initiative was to conduct a comprehensive opioid overdose vulnerability assessment in Indiana and evaluate spatial accessibility to opioid use disorder treatment, harm reduction services, and opioid response programs. We compiled 2017... (Source: SafetyLit)
Source: SafetyLit - September 18, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news