Clinical effects and outcomes of perampanel overdoses reported to U.S. poison centers - Minhaj FS, Leonard JB, Klein-Schwartz W.
INTRODUCTION: Perampanel is indicated for partial onset seizures in children and adults. The mechanism is unique among antiepileptic agents as it inhibits glutamate activity on AMPA receptors. Currently, there are few published case reports describing over... (Source: SafetyLit)
Source: SafetyLit - July 25, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Demographic pattern and mortality risk factors for prescription opioid overdose hospitalizations: results from nationwide inpatient sample analysis - Sejdiu A, Pereira KN, Joundi H, Patel YR, Basith SA, Ayala V, Mathialagan K, Majumder P.
OBJECTIVEs To explore the demographic patterns of hospitalizations related to prescription opioid overdose (POD) and evaluate the mortality risk of association in POD inpatients. METHODology We conducted a cross-sectional study using the Nationwide... (Source: SafetyLit)
Source: SafetyLit - July 25, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Drug type and risk behaviors associated with non-fatal overdose among people who use drugs: a systematic review and meta-analysis - Armoon B, SoleimanvandiAzar N, Rostami M, Higgs P, Bayani A, Bayat AH, Mohammadi R, Ahounbar E, Fattah Moghaddam L.
The present study aimed to determine the association between drug type, risk behaviors and non-fatal overdose among people who use drugs (PWUD). We searched for studies in English published before February 1, 2021, on PubMed, Scopus, Cochrane, and Web of S... (Source: SafetyLit)
Source: SafetyLit - July 25, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

US clinics slower to provide opioid treatment than Canadian clinics
(Yale University) As opioid overdose deaths rose during the COVID-19 pandemic, people seeking treatment for opioid addiction had to wait nearly twice as long to begin methadone treatment in the United States than in Canada, a new Yale study has shown. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 23, 2021 Category: International Medicine & Public Health Source Type: news

COVID-19 Caused U.S. Life Expectancy to Drop 1.5 Years
Life expectancy in the United States dropped the most in more than seven decades last year as Covid-19 sent hundreds of thousands of Americans to early deaths. The pandemic’s disproportionate toll on communities of color also widened existing gaps in life expectancy between White and Black Americans, according to estimates released by the Centers for Disease Control and Prevention. The tally represents an extraordinarily grim accounting of an ongoing catastrophe. The first year of the pandemic delivered a bigger blow to American life expectancy than any year of the Vietnam War, the AIDS crisis or the “deaths of...
Source: TIME: Health - July 21, 2021 Category: Consumer Health News Authors: John Tozzi / Bloomberg Tags: Uncategorized COVID-19 overnight wire Source Type: news

U.S. Life Expectancy Fell By 1.5 Years In 2020, The Biggest Drop Since WWII
The CDC says COVID-19 was the largest factor, along with drug overdoses, homicides, diabetes and chronic liver disease. The decline was even greater for Hispanic men than other groups.(Image credit: Andrew Lichtenstein/Corbis via Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - July 21, 2021 Category: Consumer Health News Authors: Jane Greenhalgh Source Type: news

The Federal Responses to the Drug Overdose Epidemic
Chairman Whitehouse, Co-Chairman Grassley, and members of the Senate Caucus on International Narcotics Control, thank you for inviting the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH), to participate in this hearing. (Source: NIDA News)
Source: NIDA News - July 20, 2021 Category: Addiction Tags: Opioids, Testimony, Overdose, COVID Source Type: news

How can the U.S. reduce drug overdose deaths? A wide range of ideas awaits Biden.
From decriminalization to more anti-addiction medication, the administration has many options after fatalities rose to an estimated 93,000 in 2020. But few tactics have worked. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - July 19, 2021 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news

Keyshia Cole's Mom Frankie Dead at 61, Suffered Overdose on Birthday
Frankie Lons, Keyshia's biological mother, has passed away at age 61. (Source: Reuters: Health)
Source: Reuters: Health - July 19, 2021 Category: Consumer Health News Source Type: news

How can the U.S. reduce drug overdose deaths? A wide range of ideas awaits Biden
From decriminalization to more anti-addiction medication, the administration has many options after fatalities rose to an estimated 93,000 in 2020. But few tactics have worked. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - July 18, 2021 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news

Legacies of the war on drugs: next of kin of persons who died of opioid overdose and harm reduction interventions in Philadelphia - Uzwiak BA, Hudgins A, Pizzicato LN.
BACKGROUND: Between the years 2017-2019 in Philadelphia, more than 70% of all deaths from opioid overdose occurred in a private residence. To learn more about home-based opioid use and overdose, researchers conducted qualitative interviews with next of kin... (Source: SafetyLit)
Source: SafetyLit - July 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The discounting of death: probability discounting of heroin use by fatal overdose likelihood and drug purity - Dolan SB, Johnson MW, Dunn KE, Huhn AS.
This study evaluated the influence of sample impurity and fatal overdose risk on hypothetical heroin use... (Source: SafetyLit)
Source: SafetyLit - July 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

B.C.'s prescribed safer supply program expands to reduce overdoses and deaths from illicit drugs
People in B.C. who use toxic illicit drugs and are at risk of overdosing or dying will soon be able to access alternative drugs, the minister of mental health and addictions announced Thursday. (Source: CBC | Health)
Source: CBC | Health - July 15, 2021 Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

The U.S. Reported a Record 93,000 Drug Overdose Deaths During the 2020 Pandemic Year
(NEW YORK) — Overdose deaths soared to a record 93,000 last year in the midst of the COVID-19 pandemic, the U.S. government reported Wednesday. That estimate far eclipses the high of about 72,000 drug overdose deaths reached the previous year and amounts to a 29% increase. “This is a staggering loss of human life,” said Brandon Marshall, a Brown University public health researcher who tracks overdose trends. The nation was already struggling with its worst overdose epidemic but clearly “COVID has greatly exacerbated the crisis,” he added. Lockdowns and other pandemic restrictions isolated thos...
Source: TIME: Health - July 15, 2021 Category: Consumer Health News Authors: MIKE STOBBE/AP Tags: Uncategorized Addiction COVID-19 wire Source Type: news

U.S. Drug Overdose Deaths Up ~30 Percent in 2020
Increases seen in overdose deaths from opioids, as well as cocaine and psychostimulants (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - July 14, 2021 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Institutional, Source Type: news

US overdose deaths hit record 93,000 in pandemic last year
“This is a staggering loss of human life." (Source: ABC News: Health)
Source: ABC News: Health - July 14, 2021 Category: Consumer Health News Tags: Health Source Type: news

U.S. Drug Overdose Deaths Up ~30 Percent in 2020
WEDNESDAY, July 14, 2021 -- Drug overdose deaths in the United States rose nearly 30 percent in 2020, according to provisional data released by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics. The reported... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 14, 2021 Category: Pharmaceuticals Source Type: news

Drug overdose deaths increased nearly 30% during 2020 reaching record-high 93,000, CDC reveals
Provisional CDC data show there were 93,331 drug overdose deaths recorded in the U.S. in 2020, a 29.4% jump from the 72,151 overdose fatalities reported in 2019. (Source: the Mail online | Health)
Source: the Mail online | Health - July 14, 2021 Category: Consumer Health News Source Type: news

Drug overdose deaths up nearly 30% in U.S. during pandemic-scarred 2020
Drug overdose deaths rose by nearly 30% in the United States in 2020, according to a report released Wednesday by the National Center for Health Statistics. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 14, 2021 Category: Consumer Health News Source Type: news

Liberia: Opioid Deaths Continue to Rise As Cities Reopen
[New Dawn] Tens of thousands of American lives end prematurely every year due to opioid overdoses, leaving families shattered. Dr. Paul Christo, an associate professor in the Division of Pain Medicine at the Johns Hopkins University School of Medicine, wants to remind those battling addiction to make use of telemedicine and tele-mental health services that emerged as valuable resources during the pandemic, and he adds, clinicians, need to advocate to their patients that online treatment options are available. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - July 14, 2021 Category: African Health Source Type: news

U.S. Drug Overdose Deaths Jumped Nearly 30% During Pandemic
WEDNESDAY, July 14, 2021 -- As America went into lockdown and treatment centers closed their doors, drug overdose deaths in the United States jumped by nearly a third last year, new data show. The estimated 93,331 drug overdose deaths recorded... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - July 14, 2021 Category: General Medicine Source Type: news

U.S. overdose deaths hit a record 93,000 last year in the midst of the COVID-19 pandemic, a 29% increase.
(Source: ABC News: Health)
Source: ABC News: Health - July 14, 2021 Category: Consumer Health News Tags: Health Source Type: news

Drug overdose deaths soared to a record 93,000 last year
The coronavirus pandemic and the continued spread of illegal fentanyl took a devastating toll on drug users, experts said, as the government reported a staggering increase in fatalities. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - July 14, 2021 Category: Consumer Health News Authors: Lenny Bernstein Source Type: news

Suicide attempt with isoniazid in adolescents receiving tuberculous prophylaxis: three cases - Polat E, Şenel S.
An overdose of isoniazid (INH) is potentially fatal and attempts at suicide are very rare in children. Three patients aged 14-17  years who were receiving INH for tuberculosis prophylaxis were admitted to the emergency department with generalised tonic-clo... (Source: SafetyLit)
Source: SafetyLit - July 9, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

A public health approach to protecting workers from opioid use disorder and overdose related to occupational exposure, injury, and stress: APHA Policy Statement Number 202012, issued October 24, 2020 - American Public Health Association.
Opioid overdose mortality, in combination with increased deaths from alcohol and suicide, is having a profound impact on American workplaces, compromising occupational health and safety and increasing workers' compensation and health insurance costs, absen... (Source: SafetyLit)
Source: SafetyLit - July 8, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A description of the clinical course of severe benzonatate poisonings reported in the literature and to NPDS: a systematic review supplemented with NPDS cases - Minhaj FS, Leonard JB.
BACKGROUND: Benzonatate is a commonly prescribed medication that can be lethal in acute overdose of a small number of capsules. OBJECTIVE: This was a systematic review to describe the course of severe poisoning and deaths from benzonatate supplemen... (Source: SafetyLit)
Source: SafetyLit - July 8, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Opioid deaths in Canada increased by 592% over 17-year period, University of Waterloo study indicates
Between 2000 and 2017, the number of people who died from opioid overdoses in Canada rose by 592 per cent, according to a new study from researchers at the University of Waterloo. Hospitalizations and visits to the emergency department also rose significantly. (Source: CBC | Health)
Source: CBC | Health - July 7, 2021 Category: Consumer Health News Tags: News/Canada/Kitchener-Waterloo Source Type: news

CAMH releases updated national clinical guidelines for treatment of opioid use disorder
(Centre for Addiction and Mental Health) As more evidence emerges that opioid overdose deaths have increased dramatically since the onset of COVID-19, the Centre for Addiction and Mental Health (CAMH), in collaboration with subject matter experts and medical regulatory authorities across Canada, have now released updated national clinical guidelines for the treatment of opioid use disorder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 7, 2021 Category: International Medicine & Public Health Source Type: news

Prioritising risk factors for prescription drug overdose among older adults in South Korea: a multi-method study - Lee EH, Park JO, Cho JP, Lee CA.
Older adults are vulnerable to drug overdose. We used a multi-method approach to prioritise risk factors for prescription drug overdose among older adults. The study was conducted in two stages. First, risk factors for drug overdose were classified accordi... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

"They think you're trying to get the drug": qualitative investigation of chronic pain patients' health care experiences during the opioid overdose epidemic in Canada - Dassieu L, Heino A, Develay, Kabore JL, Pag é MG, Moor G, Hudspith M, Choinière M.
BACKGROUND: The opioid overdose epidemic has led health care providers to increased vigilance for opioid-related risks in the treatment of chronic non-cancer pain (CNCP). Media have conveyed stigmatizing representations of opioid analgesics. Aims: This stu... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

How search engines may help reduce drug-related suicides - Haim M, Scherr S, Arendt F.
BACKGROUND AND AIMS: Numbers of drug-overdose deaths, both intentionally and unintentionally, have been increasing in the United States. Of interest, Google spotlights counselling services as helpful resources when users query for suicide-related search te... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Racial disparities in criminal legal system involvement among New York City overdose decedents: implications for diversion programs - Mantha S, Nolan ML, Harocopos A, Paone D.
BACKGROUND: Past studies have identified frequent criminal legal system (CLS) involvement among overdose decedents and highlight the need for connecting individuals at risk of overdose with effective interventions during CLS encounters. While some programs... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The impact of codeine upscheduling on overdoses, emergency department presentations and mortality in Victoria, Australia - Bishop M, Schumann JL, Gerostamoulos D, Wong A.
BACKGROUND AND AIMS: Prior to February 2018, codeine was available over-the-counter (OTC) in Australia as a pharmacist-only medicine (Schedule 3) in low-strength formulations when in combination with simple analgesics. In February 2018, The Advisory Commit... (Source: SafetyLit)
Source: SafetyLit - July 5, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Trends and outcomes of serious complications associated with non-fatal opioid overdoses in Ontario, Canada - Kitchen SA, McCormack D, Werb D, Caudarella A, Martins D, Matheson FI, Gomes T.
BACKGROUND: Non-fatal opioid overdoses can lead to serious complications and consequently, long-term health effects. We sought to characterize trends of hospitalizations for serious complications associated with opioid overdoses in Ontario, Canada and repo... (Source: SafetyLit)
Source: SafetyLit - July 3, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

In the pandemic's shadow, the opioid overdose epidemic in Washington rages on
While daily new COVID-19 cases are now averaging in the single digits in Washington, the opioid crisis there is showing no sign of letting up, making outreach services increasingly vital. (Source: CBC | Health)
Source: CBC | Health - July 2, 2021 Category: Consumer Health News Tags: News/World Source Type: news

Commercial fishing as an occupational determinant of opioid overdoses and deaths of despair in two Massachusetts fishing ports, 2000-2014 - Fulmer S, Jain S, Kriebel D.
This study used dea... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

During the CoViD-19 pandemic, opioid overdose deaths revert to previous record levels in Ohio - Vieson J, Yeh AB, Lan Q, Sprague JE.
The objective of this study was to identify the impact of the COVID-19 pandemic on the opioid epidemic in the state of Ohio by descri... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioid misuse as a coping behavior for unmet mental health needs among U.S. adults - Cruden G, Karmali R.
BACKGROUND: Self-medication theory posits that opioids may be misused to cope with mental or emotional distress, especially if distress is not treated. Opioid misuse may lead to opioid use disorder, overdose, and death. We estimated the risk of opioid misu... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Pulverizing medication as a harm reduction and intentional drug overdose prevention strategy: two case studies - Takanobu K, Okazaki D, Watanabe S, Mitsui N, Tanaka T.
AIMS: We explored the use of pulverized medication as a new method to prevent intentional drug overdose. METHODS: This case study presents data obtained from the medical records of two female patients, aged 19 and 27  years, who presented with schi... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Quantifying prescribed high dose opioids in the community and risk of overdose - Schofield J, Steven D, Foster R, Matheson C, Baldacchino A, McAuley A, Parkes T.
BACKGROUND: Opioid prescribing for a range of health issues is increasing globally. The risk of fatal and non-fatal overdose is increased among people prescribed strong opioids: in high doses in the context of polypharmacy (the use of multiple medications ... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Helping Drug Users Survive, Not Abstain: ‘Harm Reduction’ Gains Federal Support
Overdoses have surged during the pandemic. Now, for the first time, Congress has appropriated funds specifically for programs that distribute clean syringes and other supplies meant to protect users. (Source: NYT Health)
Source: NYT Health - June 27, 2021 Category: Consumer Health News Authors: Abby Goodnough Tags: Drug Abuse and Traffic Coronavirus (2019-nCoV) Addiction (Psychology) Naloxone (Drug) Deaths (Fatalities) Hypodermic Needles and Syringes Biden, Joseph R Jr Greensboro (NC) Fentanyl your-feed-healthcare Source Type: news

Ideal Option Data Shows a 153% Increase in Fentanyl Use in WA State
King County saw a 55% increase in fentanyl-involved overdose deaths in 2020.(PRWeb June 24, 2021)Read the full story at https://www.prweb.com/releases/ideal_option_data_shows_a_153_increase_in_fentanyl_use_in_wa_state/prweb18026366.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 24, 2021 Category: Pharmaceuticals Source Type: news

Ideal Option Data Show a 153% Increase in Fentanyl Use in WA State
King County saw a 55% increase in fentanyl-involved overdose deaths in 2020.(PRWeb June 24, 2021)Read the full story at https://www.prweb.com/releases/ideal_option_data_shows_a_153_increase_in_fentanyl_use_in_wa_state/prweb18026366.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - June 24, 2021 Category: Pharmaceuticals Source Type: news

The Pandemic Caused the Biggest Decline in U.S. Life Expectancy since World War 2. Black and Hispanic Americans Have Suffered the Most
Although James Toussaint has never had COVID-19, the pandemic is taking a profound toll on his health. First, the 57-year-old lost his job delivering parts for a New Orleans auto dealership in spring 2020, when the local economy shut down. Then, he fell behind on his rent. Last month, Toussaint was forced out of his apartment when his landlord—who refused to accept federally funded rental assistance—found a loophole in the federal ban on evictions. Toussaint has recently had trouble controlling his blood pressure. Arthritis in his back and knees prevents him from lifting more than 20 pounds, a huge obstacle for...
Source: TIME: Health - June 23, 2021 Category: Consumer Health News Authors: Liz Szabo / Kaiser Health News Tags: Uncategorized COVID-19 Source Type: news

"Zombielike" aggression in perampanel overdose - Morsi RZ, Katz JA.
We report a case of "zombielike" behavior secondary to in... (Source: SafetyLit)
Source: SafetyLit - June 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Comparing attitudes toward stigmatized deaths: suicide and opioid overdose deaths - Kheibari A, Cerel J, Victor G.
Death by suicide and opioid overdose has been associated with negative stigmatization. It is important to investigate whether a suicide death and a fatal opioid overdose share similar stigmatized reactions and how attitudes shape the public willingness to ... (Source: SafetyLit)
Source: SafetyLit - June 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Homelessness and veteran status in relation to nonfatal and fatal opioid overdose in Massachusetts - Jasuja GK, Bettano A, Smelson D, Bernson D, Rose AJ, Byrne T, Berlowitz DR, McCullough MB, Miller DR.
BACKGROUND:   Compared with non-Veterans, Veterans are at higher risk of experiencing homelessness, which is associated with opioid overdose. Objective:  To understand how homelessness and Veteran status are related to risks of nonfatal and fata... (Source: SafetyLit)
Source: SafetyLit - June 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Patterns and risk factors of opioid-suspected EMS overdose in Houston metropolitan area, 2015-2019: a Bayesian spatiotemporal analysis - Bauer C, Champagne-Langabeer T, Bakos-Block C, Zhang K, Persse D, Langabeer JR.
Background Opioid-related overdose deaths are the top accidental cause of death in the United States, and development of regional strategies to address this epidemic should begin with a better understanding of where and when overdoses are occurring. ... (Source: SafetyLit)
Source: SafetyLit - June 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Suicide safer care in behavioral health settings: a comparative analysis of perceptions, training completion, and practice between mental health and substance use disorder treatment providers - Harris BR, Tracy M, Comber KG, Pechenik S, Carruthers JW.
BACKGROUND: Despite prevention and treatment efforts, opioid overdose deaths continue to rise in the United States and totaled 46,802 in 2018. This public health crisis is closely linked with suicide, with those who misuse opioids at six times the risk of ... (Source: SafetyLit)
Source: SafetyLit - June 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A rapid-cycle assessment strategy for understanding the opioid overdose epidemic in local communities - Taubenberger S, Spencer N, Chang JC, Paul N, Fabre S, Jagessar B, Trimble D, Roberto R, Gill P, Hulsey E, Arnold A, Hacker K.
Background Certain communities in the United States experience greater opioid-involved overdose mortality than others. Interventions to stem overdose benefit from contextual understandings of communities' needs and strengths in addressing the opioid crisis... (Source: SafetyLit)
Source: SafetyLit - June 15, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news