Drug overdoses skyrocket in Washington state amid COVID
Washington state health officials say preliminary data shows more people died of drug overdoses in 2020 in the state than any year in at least the past decade (Source: ABC News: Health)
Source: ABC News: Health - May 10, 2021 Category: Consumer Health News Tags: Health Source Type: news

The influence of stigmatizing messages on danger appraisal: examining the model of stigma communication for opioid-related stigma, policy support, and related outcomes - Ledford V, Lim JR, Namkoong K, Chen J, Qin Y.
Drug overdose is a leading cause of injury and death in the United States, and opioids are among the most significant of causes. For people with opioid use disorders (OUDs), opioid stigma can lead to devastating consequences, including anxiety and depressi... (Source: SafetyLit)
Source: SafetyLit - May 6, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Can we make opioids less addictive? (video)
(American Chemical Society) Opioids are the most powerful painkillers we have, but they're incredibly addictive. Tens of thousands of people in the U.S. die of an opioid overdose every year. Will we ever have drugs that are just as good at getting rid of pain but without the risk of addiction and overdose?: https://youtu.be/8xoOF2x0XzM. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 6, 2021 Category: International Medicine & Public Health Source Type: news

Implementation of a New Hampshire community-initiated response to the opioid crisis: a mixed-methods process evaluation of Safe Station - Moore SK, Saunders EC, McLeman B, Metcalf SA, Walsh O, Bell K, Meier A, Marsch LA.
BACKGROUND: New Hampshire (NH) ranked first for fentanyl- and all opioid-related overdose deaths per capita from 2014 to 2016 and third in 2017 with no rate reduction from the previous year relative to all other states in the US. In response to the opioid ... (Source: SafetyLit)
Source: SafetyLit - May 4, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Case report: multiple seizures after a diphenoxylate-atropine overdose in a small child - Wang CH, Song LJ, Yang Y, Qu XP, Lan L, Liu B.
Poisoning is a type of accidental injury and it is considered a major public health problem worldwide. Oral drug poisoning in children is an important cause of accidental injury and even death. It is a common critical emergency in the field of pediatrics. ... (Source: SafetyLit)
Source: SafetyLit - May 4, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Suicidal behavior and club drugs in young adults - Martinotti G, Schiavone S, Negri A, Vannini C, Trabace L, De Berardis D, Pettorruso M, Sensi SL, di Giannantonio M.
In this study, we investigated s... (Source: SafetyLit)
Source: SafetyLit - May 4, 2021 Category: International Medicine & Public Health Tags: Age: Young Adults Source Type: news

Pharmacy-related buprenorphine access barriers: an audit of pharmacies in counties with a high opioid overdose burden - Kazerouni NJ, Irwin AN, Levander XA, Geddes J, Johnston K, Gostanian CJ, Mayfield BS, Montgomery BT, Graalum DC, Hartung DM.
The objective of this study was to quantify the frequency of barriers encountered by patients seeking to fill buprenorphine... (Source: SafetyLit)
Source: SafetyLit - May 4, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Community overdose surveillance: comparing substances collected from the death scene investigation to toxicology results - Lockwood TLE, Huynh P, Richard A, Sightes E, Bailey K, Ray B, Lieberman M.
BACKGROUND: Recent overdose trends are characterized by increased toxicological detection of stimulants with opioids, yet it is unclear whether these substances are mixed prior to consumption or purposefully used simultaneously. METHODS: Postmortem... (Source: SafetyLit)
Source: SafetyLit - May 4, 2021 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

FDA Approves Higher-Dose Naloxone Hydrochloride Nasal Spray
MONDAY, May 3, 2021 -- The U.S. Food and Drug Administration approved use of a higher dose of naloxone hydrochloride nasal spray for treating opioid overdose, the agency announced Friday. The newly approved dose of 8 mg provides an additional option... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 3, 2021 Category: Pharmaceuticals Source Type: news

Opioids After Dental Work May Be Dangerous
A new study warns getting a prescription for an opioid painkiller from your dentist could put you or your family at risk for an overdose. (Source: WebMD Health)
Source: WebMD Health - May 3, 2021 Category: Consumer Health News Source Type: news

FDA OKs Higher-Dose Naloxone Nasal Spray for Opioid Overdose FDA OKs Higher-Dose Naloxone Nasal Spray for Opioid Overdose
Kloxxado delivers 8 mg of naloxone into the nasal cavity, which is twice as much as the 4 mg of naloxone contained in Narcan nasal spray.FDA Approvals (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - May 3, 2021 Category: Primary Care Tags: Psychiatry News Alert Source Type: news

Opioids After Dental Work May Be Dangerous
MONDAY, May 3, 2021 -- Getting a prescription for an opioid painkiller from your dentist could put you or your family at risk for an overdose, a new study warns. The finding is based on an analysis of data from 8.5 million Americans who had teeth... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 3, 2021 Category: General Medicine Source Type: news

FDA Approves Kloxxado (naloxone hydrochloride) Nasal Spray for Emergency Treatment of Opioid Overdose
LONDON, April 30, 2021 /PRNewswire/ -- Hikma Pharmaceuticals PLC (Hikma), the multinational pharmaceutical company, announces the approval of Kloxxado (naloxone hydrochloride) nasal spray 8mg, by the US Food and Drug Administration (FDA) for the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - April 30, 2021 Category: Drugs & Pharmacology Source Type: news

US approves high-dose opioid reversal nasal spray from Hikma
U.S. regulators have approved the first high-dose nasal spray for reversing opioid overdoses (Source: ABC News: Health)
Source: ABC News: Health - April 30, 2021 Category: Consumer Health News Tags: Health Source Type: news

Treating dental pain with opioids linked to higher risk of overdose in patients & families
(Michigan Medicine - University of Michigan) Patients whose dental procedure pain was treated with opioids were more likely to have an overdose within 90 days, as were their family members, a new study of records from millions of people with private and Medicaid dental coverage shows. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 29, 2021 Category: International Medicine & Public Health Source Type: news

Validation of the Opioid Overdose Risk Behavior Scale, version 2 (ORBS-2) - Elliott L, Crasta D, Khan M, Roth A, Green T, Kolodny A, Bennett AS.
OBJECTIVE: To examine the factor structure of a revised and expanded opioid overdose risk behavior scale and assess its associations with known overdose indicators and other clinical constructs. BACKGROUND: Opioid-related overdose remains high in t... (Source: SafetyLit)
Source: SafetyLit - April 27, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

More people died from fentanyl overdose than coronavirus in San Francisco last year
(Natural News) More people died from fentanyl overdose than coronavirus (COVID-19) in San Francisco last year, a microcosm of a larger nationwide problem coinciding with the pandemic. Data from San Francisco’s Office of the Chief Medical Examiner shows that 708 people were killed by fentanyl in 2020, an astonishing 118 times more since the introduction... (Source: NaturalNews.com)
Source: NaturalNews.com - April 26, 2021 Category: Consumer Health News Source Type: news

Continuous venovenous hemofiltration as a rescue therapy for severe acetaminophen toxicity in a toddler - Awasthi P, Jindal A, Sharma Y, Williams V, Ravikumar N, Nallasamy K, Angurana SK.
Acetaminophen poisoning is one of the common accidental poisoning in children. Accidental administration of mismatched doses of drops for syrups can lead to life-threatening overdose. N-acetylcysteine (NAC) is the specific antidote; however, extracorporeal... (Source: SafetyLit)
Source: SafetyLit - April 26, 2021 Category: International Medicine & Public Health Tags: Age: Infants and Children Source Type: news

Decision-making by laypersons equipped with an emergency response smartphone app for opioid overdose - Ataiants J, Reed MK, Schwartz DG, Roth A, Marcu G, Lankenau SE.
This study explored h... (Source: SafetyLit)
Source: SafetyLit - April 26, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Suicide as a hidden contributor to the opioid crisis and the role that primary care and emergency medicine play in addressing it - Harris BR.
Deaths from overdose have risen dramatically over the past decade, driven mainly by opioids. In response, the Centers for Disease Control and Prevention released guidance on safe prescribing, safe storage of medications, Medication-Assisted Treatment (MAT)... (Source: SafetyLit)
Source: SafetyLit - April 26, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

A rare presentation of anticholinergic toxicity in a young patient due to over-the-counter cold medicines - Khan A, Singh G, Jacob J.
Anticholinergic toxicity is a relatively uncommon occurrence. When it does occur, it is usually attributed to an overdose of anticholinergic agents, especially in the elderly population. In younger patients, anticholingeric toxicity is usually due to an in... (Source: SafetyLit)
Source: SafetyLit - April 23, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Cannabis use and suicidal behavior and long-term harms - Fu XL, Chen HL.
To the Editor In a population-based study, Fontanella et al observed that cannabis use disorder is a common comorbidity and risk marker for self-harm, all-cause mortality, and death by unintentional overdose and homicide among youths with mood disorders. H... (Source: SafetyLit)
Source: SafetyLit - April 22, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Breaching trust: a qualitative study of healthcare experiences of people who use drugs in a rural setting - Ellis K, Walters S, Friedman SR, Ouellet LJ, Ezell J, Rosentel K, Pho MT.
BACKGROUND: Increased drug use has disproportionately impacted rural areas across the U.S. People who use drugs are at risk of overdose and other medical complications, including infectious diseases. Understanding barriers to healthcare access for this oft... (Source: SafetyLit)
Source: SafetyLit - April 22, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Surviving traumatic injury, only to die of acute drug poisoning: should trauma centers be a path for intervention? - Bongiovanni T, Hernandez S, Ledesma Y, Menza R, Wick E, Steinman M, Mackersie R, Stein DM, Coffin PO.
BACKGROUND: Although death from drug overdose is a leading cause of injury-related death in the United States, its incidence after traumatic incident is unknown. Moreover, little is known about related risk factors. We sought to determine the incidence and... (Source: SafetyLit)
Source: SafetyLit - April 22, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

77 inmates at Iowa prison given overdoses of COVID-19 vaccine, officials say
Dozens of inmates at an Iowa prison were given overdoses of a COVID-19 vaccine, officials said. (Source: Reuters: Health)
Source: Reuters: Health - April 22, 2021 Category: Consumer Health News Source Type: news

Pandemic-Fueled Drug Abuse Threatens Hearts, Lives
A preliminary CDC summary counted nearly 90,000 overdose deaths in the 12 months ending in September 2020, a 29% increase from the previous period. (Source: WebMD Health)
Source: WebMD Health - April 21, 2021 Category: Consumer Health News Source Type: news

Pandemic Has Blocked Access to Treatment for Many Americans Hooked on Opioids
WEDNESDAY, April 21, 2021 -- The COVID-19 pandemic may have kept some Americans from getting vital medication to treat opioid addiction -- possibly contributing to the national surge in overdose deaths, a new study suggests. Researchers found that... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 21, 2021 Category: General Medicine Source Type: news

Large numbers of regular drug users report increased substance use during COVID-19
(Centre for Addiction and Mental Health) People who regularly use psychoactive substances report experiencing a variety of negative impacts since the COVID-19 pandemic began, including increased usage and fear of relapse or overdose, highlighting the need for improved supports and services, including better access to safe supply programs, according to a new CAMH survey published in the International Journal of Drug Policy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 20, 2021 Category: International Medicine & Public Health Source Type: news

Involuntary stabilization care of youth who overdose: a call for evidence- and ethics-informed substance use policy - Goodyear T, Robinson S, Jenkins E, Gagnon M, Mitchell K, Knight R.
As is the case across Canada, the province of British Columbia is in the midst of an opioid overdose crisis. In response to the devastating impacts of this crisis on youth (under 19  years of age), the provincial government is considering amending the Ment... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Fatal self-injury in the United States, 1999- 2018: unmasking a national mental health crisis-Authors' reply - Rockett IRH, Caine ED, Connery HS.
Santaella-Tenorio and colleagues write that our conception of self-injury mortality (SIM) "reduces the complexity of fatal overdoses while perpetuating a stigmatizing narrative of people who use drugs, an already marginalized population, as careless and in... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Letter on Rocket's et  al., manuscript: Fatal self-injury in the United States, 1999-2018: unmasking a national mental health crisis - Santaella-Tenorio J, Townsend T, Krawczyk N, Frank D, Friedman SR.
Rockett et al. propose a self-injury measure (SIM) to mitigate uncertainty in injury intention of death determinations. Their argument for fitting 80% of unintentional overdoses into the SIM "is predicated on the presence of repetitive self-harm behaviors,... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Longitudinal opioid surveillance project involving toxicologic analysis of postmortem specimens from 9 counties in Michigan suggests the discovery of new high-intensity drug trafficking areas - Stevens C, Li T, Ton E, Zou J, Douglas E, Jones P.
Acetyl fentanyl (AF) is a Schedule I fentanyl analog that has been increasingly seen in heroin and fentanyl polydrug toxicity overdoses in Michigan (MI). Drug users are often unaware of the presence of AF in their drugs because it is often sold mixed into ... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Performance of a predictive model versus prescription-based thresholds in identifying patients at risk of fatal opioid overdose - Ferris LM, Saloner B, Jackson K, Lyons BC, Murthy V, Kharrazi H, Latimore A, Stuart EA, Weiner JP.
BACKGROUND: Prescription Drug Monitoring Programs (PDMPs) collect controlled substance prescriptions dispensed within a state. Many PDMP programs perform targeted outreach (i.e., "unsolicited reporting") for patients who exceed numerical thresholds, howeve... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

State-level economic costs of opioid use disorder and fatal opioid overdose - United States, 2017 - Luo F, Li M, Florence C.
Approximately 47,000 persons in the United States died from an opioid-involved overdose in 2018 (1), and 2.0 million persons met the diagnostic criteria for an opioid use disorder in 2017 (2). The economic cost of the U.S. opioid epidemic in 2017 was estim... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Trends in substances involved in polysubstance overdose fatalities in Maryland, USA 2003-2019 - Schneider KE, Nestadt PS, Shaw BR, Park JN.
BACKGROUND: The substances driving the overdose epidemic in the United States have changed over time. Since 2013, fentanyl-analogues have become the primary opioids driving the epidemic. Recently, polysubstance related deaths have come to the forefront of ... (Source: SafetyLit)
Source: SafetyLit - April 19, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Opioid vaccine in the works
(University of Houston) Amid the rise in opioid overdoses during the COVID-19 pandemic, a University of Houston researcher has joined a team developing a vaccine for opioid use disorder. The vaccine targets fentanyl, a synthetic and very potent opioid, often added into street drugs. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 19, 2021 Category: International Medicine & Public Health Source Type: news

Back from the dead: a case of bupropion overdose mimicking brain death - Pelletier JN, Ie SR, Stromberg PE, Perkins JC.
We describe a case of a 43-year-old female who was found unresponsive after an intentional overdose of bupropion and cyclobenzaprine. Upon transfer to our hospital she began to exhibit signs of Brain Death (BD). Electroencephalogram (EEG) showed burst supp... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Neither ethical nor effective: the false promise of involuntary commitment to address the overdose crisis [editorial] - Sinha MS, Messinger JC, Beletsky L.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Pathways between COVID-19 public health responses and increasing overdose risks: a rapid review and conceptual framework - Nguyen T, Buxton JA.
BACKGROUND: Emerging evidence indicates that illicit drug overdoses are increasing throughout the COVID-19 pandemic. There is a paucity of evidence on the causative pathways for this trend, but expert opinions, commentaries, and some reviews offer theoreti... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Prevalence and correlates of multiple non-fatal opioid overdoses among people who inject drugs who utilise needle syringe programs in Australia - Geddes L, Iversen J, Darke S, Dietze P, Maher L.
BACKGROUND: Non-fatal overdose (NFOD) is a major cause of morbidity among people who inject drugs (PWID) and multiple NFOD is associated with increased risk of fatal overdose. Despite this, few studies have examined the prevalence and correlates of drug-sp... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Rethinking 'carriage' of take-home naloxone - McDonald R, Parkin S, Eide D, Neale J, Clausen T, Metrebian N, Carter B, Strang J.
Take-home naloxone (THN) provision to people who use drugs, their family/friends, and non-medical personnel is considered a public health strategy to improve community-based naloxone access and reduce the time to antidote treatment for opioid overdose in o... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

The health care system as champion to curb the drug overdose crisis [editorial] - Barenie RE.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - April 17, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Nation’s health by the numbers can be found at CDC-affiliated blog
The National Center for Health Statistics compiles and releases tons of data on such issues as coronavirus deaths, drug overdoses, mental health and others. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 17, 2021 Category: Consumer Health News Authors: Erin Blakemore Source Type: news

U.S. Overdose Deaths Have Soared During COVID - 19 Pandemic
Increase largely driven by illicitly manufactured fentanyl and other synthetic opioids (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - April 16, 2021 Category: Psychiatry Tags: Family Medicine, Internal Medicine, Emergency Medicine, Pharmacy, Psychiatry, Institutional, Source Type: news

U.S. Overdose Deaths Have Soared During COVID-19 Pandemic
THURSDAY, April 15, 2021 -- There were more than 87,000 drug overdose deaths in the United States from October 2019 to September 2020, the highest of any one-year period since the nation's opioid crisis began in the 1990s, preliminary government... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 15, 2021 Category: Pharmaceuticals Source Type: news

State-Level Economic Costs of Opioid Use Disorder and Fatal Opioid Overdose - United States, 2017
This report describes state-level costs of opioid use disorder and fatal opioid overdose in the United States for 2017. (Source: CDC Morbidity and Mortality Weekly Report)
Source: CDC Morbidity and Mortality Weekly Report - April 15, 2021 Category: American Health Tags: MMWR Morbidity & Mortality Weekly Report Opioids Schools Source Type: news

COVID-19 reduces access to opioid dependency treatment for new patients
(Princeton University, Woodrow Wilson School of Public and International Affairs) COVID-19 has been associated with increases in opioid overdose deaths, which may be in part because the pandemic limited access to buprenorphine, a treatment used for opioid dependency, according to a new study led by Princeton University researchers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 15, 2021 Category: International Medicine & Public Health Source Type: news

Drug Overdose Deaths Have Surged During the Pandemic, C.D.C. Says
The latest numbers surpass even the yearly tolls during the height of the opioid epidemic and mark a reversal of progress against addiction in recent years. (Source: NYT Health)
Source: NYT Health - April 15, 2021 Category: Consumer Health News Authors: Abby Goodnough Tags: Drug Abuse and Traffic Coronavirus (2019-nCoV) Addiction (Psychology) Buprenorphine (Drug) Opioids and Opiates Deaths (Fatalities) Fentanyl Methamphetamines Hypodermic Needles and Syringes Native Americans Centers for Disease Control a Source Type: news

Drug overdose mortality in Ohio during 1st 7 months of COVID-19 pandemic
(JAMA Network) What The Study Did: Data from the Ohio Department of Health were used to evaluate changes in drug overdose mortality in that state by type of drug and age of the user during the first seven months of the COVID-19 epidemic. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 14, 2021 Category: Infectious Diseases Source Type: news

Paracetamol overdose: Two ‘extremely common’ side effects of overdosing paracetamol
PARACETAMOL is a popular painkiller used to treat aches and pain. Although taking the recommended dose is safe for most people, overdosing can cause adverse reactions. (Source: Daily Express - Health)
Source: Daily Express - Health - April 12, 2021 Category: Consumer Health News Source Type: news