Disulfiram encephalopathy: an underrecognized complication of accidental overdose
We describe the pathophysiology behind this complication and reflect on some important numbers.PMID:38650532 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - April 23, 2024 Category: Psychiatry Authors: A De Decker J De Fruyt Source Type: research

Prevalence of Opioid Use Disorder and Opioid Overdose Rates Among People With Mental Illness
CONCLUSIONS: These findings underscore the importance of providing opioid use disorder screening and treatment for patients receiving psychiatric services.PMID:38650488 | DOI:10.1176/appi.ps.20230338 (Source: Psychiatric Services)
Source: Psychiatric Services - April 23, 2024 Category: Psychiatry Authors: Qingxian Chen Manesh Gopaldas Felipe Castillo Emily Leckman-Westin Edward V Nunes Frances R Levin Molly T Finnerty Source Type: research

Prevalence of Opioid Use Disorder and Opioid Overdose Rates Among People With Mental Illness
Psychiatric Services, Ahead of Print. (Source: Psychiatric Services)
Source: Psychiatric Services - April 23, 2024 Category: Psychiatry Authors: Qingxian Chen Manesh Gopaldas Felipe Castillo Emily Leckman-Westin Edward V. Nunes Frances R. Levin Molly T. Finnerty Source Type: research

Opioid Overdose Knowledge Among Adolescents and Young Adults
This cross-sectional study examines awareness of opioid overdose, the ability to administer naloxone, and the willingness to help during an overdose on college campuses across the US. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - April 22, 2024 Category: Pediatrics Source Type: research

The Overdose Crisis in the 2024 Election —Political Fights and Practical Problems
This Viewpoint discusses the 2024 presidential election in the context of the addiction and overdose crisis in the US, which has been a unifying challenge and a source of major ideological division in US politics. (Source: JAMA - Journal of the American Medical Association)
Source: JAMA - Journal of the American Medical Association - April 22, 2024 Category: General Medicine Source Type: research

Molecules, Vol. 29, Pages 1881: CB1 Receptor Negative Allosteric Modulators as a Potential Tool to Reverse Cannabinoid Toxicity
ackie Alex Straiker While the opioid crisis has justifiably occupied news headlines, emergency rooms are seeing many thousands of visits for another cause: cannabinoid toxicity. This is partly due to the spread of cheap and extremely potent synthetic cannabinoids that can cause serious neurological and cardiovascular complications—and deaths—every year. While an opioid overdose can be reversed by naloxone, there is no analogous treatment for cannabis toxicity. Without an antidote, doctors rely on sedatives, with their own risks, or ‘waiting it out’ to treat thes...
Source: Molecules - April 20, 2024 Category: Chemistry Authors: Audrey Flavin Paniz Azizi Natalia Murataeva Kyle Yust Wenwen Du Ruth Ross Iain Greig Thuy Nguyen Yanan Zhang Ken Mackie Alex Straiker Tags: Article Source Type: research

A Deep Dive into Opioid Antagonist Use for Opioid-Induced Respiratory Depression (OIRD)
1. Utilizing a case-based approach, participants will be able to 1) Describe the pathophysiology of opioid-induced respiratory depression (OIRD); 2) Differentiate the pharmacology and formulations of naloxone and nalmefene to mitigate OIRD in the hospice and2. 3) Discuss the use of naloxone and risks in polysubstance overdoses; 4) Identify patients who may or may not benefit from naloxone or nalmefene depending on concurrent antagonists which may prevent or modulate OIRD; 5) Recommend opportunities to optimize. (Source: Journal of Pain and Symptom Management)
Source: Journal of Pain and Symptom Management - April 19, 2024 Category: Palliative Care Authors: Sandra Discala, Mellar P. Davis, Amy Davis, Alan S. Rozen Source Type: research

Autonomy-Based Obligations to Patients in the Emergency Department Following Opioid Overdose
Am J Bioeth. 2024 May;24(5):56-58. doi: 10.1080/15265161.2024.2329252. Epub 2024 Apr 18.NO ABSTRACTPMID:38635432 | DOI:10.1080/15265161.2024.2329252 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Grayson Holt Ben Schwan Source Type: research

Confidence in Care Instead of Capacity: A Feminist Approach to Opioid Overdose
Am J Bioeth. 2024 May;24(5):51-53. doi: 10.1080/15265161.2024.2327278. Epub 2024 Apr 18.NO ABSTRACTPMID:38635431 | DOI:10.1080/15265161.2024.2327278 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Jessica Olivares Emma Tumilty Lisa Campo-Engelstein Kathryn A Cunningham Source Type: research

Illuminating the Consequentialist Logic of Harm Reduction After Overdose Through a Hypothetical Randomized Trial
Am J Bioeth. 2024 May;24(5):45-48. doi: 10.1080/15265161.2024.2327277. Epub 2024 Apr 18.NO ABSTRACTPMID:38635430 | DOI:10.1080/15265161.2024.2327277 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Kevin R Riggs Stefan G Kertesz Source Type: research

Opioid Overdose and Capacity
Am J Bioeth. 2024 May;24(5):33-34. doi: 10.1080/15265161.2024.2327298. Epub 2024 Apr 18.NO ABSTRACTPMID:38635426 | DOI:10.1080/15265161.2024.2327298 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Catherine A Marco Source Type: research

Revive and Survive: A Critical Lens on the Refusal of Care After Opioid Overdose
Am J Bioeth. 2024 May;24(5):30-33. doi: 10.1080/15265161.2024.2327280. Epub 2024 Apr 18.NO ABSTRACTPMID:38635425 | DOI:10.1080/15265161.2024.2327280 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Harjeev Kour Sudan Quinn Boyle Thomas Kerr Mypinder Sekhon Judy Illes Source Type: research

Why Patients Leave: The Role of Stigma and Discrimination in Decisions to Refuse Post-Overdose Treatment
Am J Bioeth. 2024 May;24(5):1-5. doi: 10.1080/15265161.2024.2333219. Epub 2024 Apr 18.NO ABSTRACTPMID:38635422 | DOI:10.1080/15265161.2024.2333219 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Kassandra Frederique Aaron Ferguson Zo ё Dodd Source Type: research

From Opioid Overdose to LVAD Refusals: Navigating the Spectrum of Decisional Autonomy
Am J Bioeth. 2024 May;24(5):8-10. doi: 10.1080/15265161.2024.2329496. Epub 2024 Apr 18.NO ABSTRACTPMID:38635427 | DOI:10.1080/15265161.2024.2329496 (Source: The American Journal of Bioethics : AJOB)
Source: The American Journal of Bioethics : AJOB - April 18, 2024 Category: Medical Ethics Authors: Jared N Smith Joanna Smolenski Ben H Lang Jennifer Blumenthal-Barby Source Type: research

Self-Reported Disability Type and Risk of Alcohol-Induced Death - A Longitudinal Study Using Nationally Representative Data
CONCLUSIONS: The risk of alcohol-induced death varies considerably by disability type. Efforts to prevent alcohol-induced deaths should be tailored to meet the needs of the highest-risk groups, including adults with complex activity (i.e., activities of daily living - "ALDs"), vision, mobility, and ≥2 limitations. Early diagnosis and treatment of alcohol use disorder within these populations, and improved access to educational and occupational opportunities, should be considered as prevention strategies for alcohol-induced deaths.PMID:38635979 | DOI:10.1080/10826084.2024.2340993 (Source: Substance Use and Misuse)
Source: Substance Use and Misuse - April 18, 2024 Category: Addiction Authors: Jonathan Aram Natalie Slopen Candace Cosgrove Amelia Arria Hongjie Liu Cher M Dallal Source Type: research