HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Funding Opportunity PAR-24-197 from the NIH Guide for Grants and Contracts. The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to identify new druggable targets for pain within the understudied druggable proteome. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s) listed in this NOFO. This NOFO is intended to jumpstart research on understudied proteins within the context of pain and pain management and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the charac...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 17, 2024 Category: Research Source Type: funding

Notice of Special Interest (NOSI) regarding the Availability of Urgent Competitive Revisions for Coordinating Center Infrastructure to Support Research on Opioid Overdose and HIV Risk in the Context of Justice Systems
Notice NOT-DA-24-013 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 4, 2024 Category: Research Source Type: funding

Lethal Means Safety Suicide Prevention Research in Healthcare and Community Settings (R34 Clinical Trial Required)
Funding Opportunity RFA-MH-25-120 from the NIH Guide for Grants and Contracts. NIMH seeks applications to evaluate the preliminary effectiveness of therapeutic and service delivery interventions that utilize lethal means safety strategies to reduce suicide risk in healthcare and community settings. Behavioral health clinics that incorporate lethal means counseling into their programming have been associated with significant reductions in suicide attempts and death. Yet, the field is lacking strong evidence on the effectiveness of these strategies tested in healthcare and community settings. Pilot effectiveness research ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 18, 2024 Category: Research Source Type: funding

South Dakota Communities That Care Grants
Grants to support South Dakota communities in implementing the CDC's Communities That Care prevention system to strengthen protective factors among youth and help prevent, reduce, and respond to behavioral risk factors such as substance misuse, overdose, and suicide. Rural communities are a priority. Geographic coverage: South Dakota -- South Dakota Department of Health (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - March 15, 2024 Category: American Health Source Type: funding

Notice of Special Interest (NOSI): Saving Lives: Integrating Overdose Education and Naloxone Distribution (OEND) into HIV Prevention and Care Settings for People Who Use Addictive Substances
Notice NOT-DA-25-031 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 8, 2024 Category: Research Source Type: funding

Notice of Change to RFA-DA-23-054, "HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R33 Clinical Trial Optional)"
Notice NOT-DA-23-055 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 13, 2024 Category: Research Source Type: funding

Notice of Change to RFA-DA-23-053, "HEAL Initiative: Translating Research to Practice to End the Overdose Crisis (R61/R33 Clinical Trial Optional)"
Notice NOT-DA-23-054 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 8, 2024 Category: Research Source Type: funding

North Dakota Opioid Settlement Fund Grant
Grants for opioid use prevention and overdose prevention in North Dakota, including best practices relating to fentanyl drug overdose and workforce development activities. Geographic coverage: North Dakota -- North Dakota Department of Health (Source: Emergency services funding opportunities via the Rural Assistance Center)
Source: Emergency services funding opportunities via the Rural Assistance Center - December 15, 2023 Category: Rural Health Source Type: funding

Adolescent Overdose Prevention and SUD Treatment Initiative (R21 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-25-030 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages exploratory and developmental research to better understand adolescent illicit fentanyl use and overdose patterns among youth at high risk for overdose. Research studies should identify targets for overdose prevention and substance use disorder (SUD) treatment and recovery. Research studies may use a variety of approaches (e.g., leveraging existing data sources, survey research, social network analysis, new methods development, feasibility research). Outcomes of interest include but are n...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 17, 2023 Category: Research Source Type: funding

Adolescent Overdose Prevention and SUD Treatment Initiative (R34 - Clinical Trial Optional)
Funding Opportunity RFA-DA-25-031 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) encourages pilot work and preliminary research to support preparation for large-scale, rigorous trials that will guide the expansion of effective, non-stigmatizing overdose prevention, SUD treatment and recovery services for adolescents. These studies could include examining changes in risk behaviors associated with overdose (e.g., using alone, carrying/using Naloxone). Outcomes of interest include but are not limited to harm reduction, recovery, treatment retention and effectiveness, quality of care,...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 17, 2023 Category: Research Source Type: funding

Tribal Naloxone Allocation
As part of a settlement with a pharmaceutical company, tribes are eligible to receive free boxes of the opioid overdose emergency treatment medication, Naloxone, each year for 10 years. Geographic coverage: Nationwide -- National Indian Health Board (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - October 9, 2023 Category: American Health Source Type: funding

HEAL Initiative: Developing an Evidence Base for Co-Occurring OUD-AUD Interventions (R34 Clinical Trial Optional)
Funding Opportunity RFA-AA-23-006 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) seeks to support studies that will inform safe and effective medication-assisted, psychosocial, and complementary interventions for people with co-occurring Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD). Alcohol increases lethal opioid overdose risk. As a result, treatment providers may under-prescribe or be reluctant to provide opioid agonist therapies (OATs) such as methadone and buprenorphine to people with OUD who also have AUD or misuse alcohol. There is also scant research on non-phar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 11, 2023 Category: Research Source Type: funding

HEAL Initiative: Developing an Evidence Base for Co-Occurring OUD-AUD Interventions (R01 Clinical Trial Optional)
Funding Opportunity RFA-AA-23-005 from the NIH Guide for Grants and Contracts. This notice of funding opportunity (NOFO) seeks to support studies that will inform safe and effective medication-assisted, psychosocial, and complementary interventions for people with co-occurring Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD). Alcohol increases lethal opioid overdose risk. As a result, treatment providers may under-prescribe or be reluctant to provide opioid agonist therapies (OATs) such as methadone and buprenorphine to people with OUD who also have AUD or misuse alcohol. There is also scant research on non-phar...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 11, 2023 Category: Research Source Type: funding

Notice of Intent to Publish a Funding Opportunity Announcement for Justice Community Overdose Innovation Network - Phase II Research Hubs (U01 Clinical Trial Required)
Notice NOT-DA-25-025 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 21, 2023 Category: Research Source Type: funding

HEAL Initiative: Justice Community Overdose Innovation Network (JCOIN) - Phase II Coordination and Translation Center (U2C Clinical Trial Optional)
Funding Opportunity RFA-DA-24-069 from the NIH Guide for Grants and Contracts. The intersection of criminal-legal and community-based health systems is a critical target for addressing the overdose crisis. To support research on effective interventions and implementation strategies, the National Institute on Drug Abuse intends to continue the Justice Community Overdose Innovation Network (JCOIN) Phase II. The purpose of the network is to bring together a national consortium of investigators and practitioner partners to conduct an array of research and capacity building activities to address the overdose epidemic among i...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 21, 2023 Category: Research Source Type: funding