Potential Role of Biofilm Formation in the Development of Digestive Tract Cancer With Special Reference to Helicobacter pylori Infection
Potential Role of Biofilm Formation in the Development of Digestive Tract Cancer With Special Reference to Helicobacter pylori Infection Cosmeri Rizzato1, Javier Torres2, Elena Kasamatsu3, Margarita Camorlinga-Ponce2, Maria Mercedes Bravo4, Federico Canzian5 and Ikuko Kato6* 1Department of Translation Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy 2Unidad de Investigación en Enfermedades Infecciosas, Unidades Médicas de Alta Especialidad Pediatría, Instituto Mexicano del Seguro Social, Mexico City, Mexico 3Instituto de Investigaciones en Ciencias de la Salud, National University of Asunción, Asunción, Paraguay 4Grupo de Investigación en Biología del Cáncer, Instituto Nacional de Cancerología, Bogotá, Colombia 5Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany 6Department of Oncology and Pathology, Wayne State University School of Medicine, Detroit, MI, United States Bacteria are highly social organisms that communicate via signaling molecules and can assume a multicellular lifestyle to build biofilm communities. Until recently, complications from biofilm-associated infection have been primarily ascribed to increased bacterial resistance to antibiotics and host immune evasion, leading to persistent infection. In this theory and hypothesis article we present a relatively new argument that biofilm formation has potenti...
ConclusionLow pH affected the survival of Lactobacillus casei under refrigeration; even when Lactobacillus casei were microencapsulated, acidic conditions impacted viability. Although pH affects viability, its value is very sensitive and will depend on the fruit juice and its composition. Some fruit juices contain compounds used as substrates for Lactobacillus and other compounds with antimicrobial effects.
Publication date: Available online 22 October 2019Source: Biosensors and BioelectronicsAuthor(s): Mohammed Sedki, Xingyu Chen, Chuan Chen, Xin Ge, Ashok MulchandaniAbstractA highly sensitive and selective non-lytic M13 phage-based electrochemical impedance spectroscopy (EIS) cytosensor for early detection of coliforms is introduced for the first time. AuNPs were electrochemically deposited on the surface of glassy carbon electrode, and the M13 phage particles were immobilized on them using 3-mercaptopropanoic acid linker and zero-length crosslinking chemistry (EDC/NHS). Next, the sensor surface was blocked to avoid non-spe...
Publication date: Available online 22 October 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Shradhanjali Singh, Shanti Bhushan Mishra, Alok MukerjeeAbstractThe plant Clerodendrum serratum (L.) Moon has been traditionally claimed for the treatment of various inflammatory conditions including rheumatoid arthritis, hence in the present study the effect of the crude ethanolic extract (CSEE) from leaves of the plant and its chloroform fraction (CSCF) were evaluated in acute and chronic arthritic model. Preliminary phytochemical screening was performed for CSEE and chloroform fraction (CSCF). Formaldehyde (2%...
Publication date: Available online 23 October 2019Source: Molecular and Cellular ProbesAuthor(s): Yi ChenAbstractCyclooxygenase-2 (COX-2) is an inducible enzyme that plays a key role in the inflammatory cascade through the generation of prostaglandins. Recent studies have found that COX-2 is closely related to the occurrence and development of tumors, angiogenesis and metastasis of tumors. Overexpressed COX-2 has become a predictive biomarker for progression of pre-malignant towards cancer in some tissues, which makes the detection of COX-2 of great value and clinical significance. This review highlights COX-2-specific flu...
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02129A, CommunicationYouping Tian, Yi Gong, Xiao-Si Hu, Jin-Sheng Yu, Ying Zhou, Jian Zhou A highly efficient metal-free aldol-type reaction of various acetals or ketals with fluorinated silyl enol ethers catalysed by less than 1 mol% HClO4 (70% wt., aq.) is developed. This provides... The content of this RSS Feed (c) The Royal Society of Chemistry
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB01967G, PaperYi He, Thomas Narmon, Danjun WU, Zhenghua Li, Luc Van Meervelt, Erik V Van der Eycken A rapid approach for the diversity-oriented synthesis of complex bridged polycyclic N-heterocycles from readily available starting materials in two operational steps has been developed. This strategy firstly introduces molecular diversity... The content of this RSS Feed (c) The Royal Society of Chemistry
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02165E, PaperDengke Li, Jian Lei A method for the synthesis of 2-thiolated benzimidazoles is described starting from thiols and 1-azido-2-isocyanoarenes. The isocyano group works as acceptor of various thio radicals, followed by denitrogenative annulation of... The content of this RSS Feed (c) The Royal Society of Chemistry
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02138H, PaperChen Zhou, Chen Hu, Gang Hong, Yuchen He, Zhicong Tang, Limin Wang A highly efficient dehydrogenative reaction of a series of nucleophiles with 9-aryl-fluoren-9-ols has been realized by using only 2 mol % of Sc(OTf)3 as catalyst. The corresponding indole-containing 9,9-diarylfluorenes were... The content of this RSS Feed (c) The Royal Society of Chemistry
Org. Biomol. Chem., 2019, Advance Article DOI: 10.1039/C9OB02079A, PaperAdam Forman, Roland Pfoh, Alexander Eddenden, P. Lynne Howell, Mark Nitz Mono-de-N-acetylated β-(1→6)-N-acetyl-D-glucosamine penta- and hepta-saccharides were obtained using a convergent synthesis. The site of de-N-acetylation drives the selectivity of hydrolysis by PgaB. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Org. Biomol. Chem., 2019, Accepted Manuscript DOI: 10.1039/C9OB02065A, PaperLaurent El Kaim, Mahanandaiah Kurva, Mansour Dol é Kerim, Rocío Gámez-Montaño The Ugi reaction of 2-nitrobenzoic acid derivatives has been used for a Diversity Oriented Synthesis of complex isoindolinones via a SNAr reaction involving the peptidyl position. When the cyclization is... The content of this RSS Feed (c) The Royal Society of Chemistry
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