Medical News Today: How do cancer-causing bacteria take over our stomachs?
H. pylori live in the stomachs of around 50% of all humans. Despite their prevalence, little is known about how they can survive inside us for a lifetime. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 8, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

RedHill Biopharma Submits New Drug Application for Talicia for H. pylori Infection
TEL-AVIV, Israel and RALEIGH, N.C., May 7, 2019 -- RedHill Biopharma Ltd. (Nasdaq: RDHL) (Tel-Aviv Stock Exchange: RDHL) (“RedHill” or the“Company”), a specialty biopharmaceutical company primarily focused on... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - May 7, 2019 Category: Drugs & Pharmacology Source Type: news

Image of the Day: Gastric Colonies
Scientists map the presence of Helicobacter pylori in the stomach of mice, showing where the bacteria colonize the gastric glands. (Source: The Scientist)
Source: The Scientist - May 6, 2019 Category: Science Tags: Image of the Day Source Type: news

Machine Learning Model to Predict Recurrent Ulcer Bleeding Machine Learning Model to Predict Recurrent Ulcer Bleeding
The authors present a novel clinical and laboratory parameter-based prediction model to predict recurrent ulcer bleeding in patients with a history of H. pylori-negative idiopathic bleeding ulcers.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 6, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Pathogens find safe harbor deep in the gastric glands
(PLOS) Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach. In a new study publishing May 2 in the open-access journal PLOS Biology, researchers led by Connie Fung and Manuel Amieva at Stanford University propose that H. pylori exploit a specialized niche that provides safe harbor deep in the gastric glands to maintain lifelong colonization. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 2, 2019 Category: Cancer & Oncology Source Type: news

Reservoir bugs: Stanford-led study shows why stomach pathogen is so tough to eradicate
(Stanford Medicine) Once the stomach-dwelling bacteria Helicobacter pylori is established in the stomach, Stanford University School of Medicine investigators have learned that even competing strains of the same species can't displace it. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 2, 2019 Category: Infectious Diseases Source Type: news

Gut Brain Axis
Helicobacter pylori Induced Anxiety and AnorexiaOurPGP9.5 was used as a Hypothalamic Neuronal Marker in this study-Hajime Suzuki, Koji Ataka, Akihiro Asakawa, Kai-Chun Cheng, Miharu Ushikai, Haruki Iwai, Takakazu Yagi, Takeshi Arai, Kinnosuke Yahiro, Katsuhiro Yamamoto, Yoshito Yokoyama, Masayasu Kojima, Toshihiko Yada, Toshiya Hirayama, Norifumi Nakamura& Akio Inui (2019).Helicobacter pylori Vacuolating Cytotoxin A Causes Anorexia and Anxiety via Hypothalamic Urocortin 1 in Mice. Scientific Reports volume 9, Article number: 6011.Images: Ucn1- and DAPI-positive cells (yellow arrow heads), or Ucn1- and PGP9.5-positive c...
Source: Neuromics - April 17, 2019 Category: Neuroscience Tags: Gut-Brain Axis. Hypothalamus Helicobacter pylori Hypothalamic Neurons PGP9.5 Antibody Protein Gene Product 9.5 Source Type: news

New study explains how inflammation causes gastric cancer
(Kanazawa University) Researchers from Kanazawa University and the Japan Agency for Medical Research and Development have solved the decades-old mystery of how stomach bacterium Helicobacter pylori causes gastric cancer. Using mouse models and human cancer cell lines, they showed that inflammation resulting from bacterial infection leads to the proliferation of gastric epithelial cells, which ultimately form gastric tumors. By blocking the protein pathway responsible for this proliferation, they prevented gastric tumor formation. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 16, 2019 Category: Biology Source Type: news

Cancer prevention drug also disables H. pylori bacterium
(Vanderbilt University Medical Center) A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 28, 2019 Category: Cancer & Oncology Source Type: news

Study reveals key details about bacterium that increases risk for stomach cancer
More than half of the people in the world host colonies of a bacterium called Helicobacter pylori in their stomachs.Although it ’s harmless to many, H. pylori can cause stomach cancer as well as ulcers and other gastric conditions. Doctors tend to prescribe multiple antibiotics to defeat the microbe, but that strategy can lead to antibiotic-resistant superbugs.Now, afinding by UCLA scientists may lead to a better approach. The researchers have determined the molecular structure of a protein that enables H. pylori to stay alive in the stomach, and elucidated the mechanism by which that protein works.Z. Hong Zhou, the ...
Source: UCLA Newsroom: Health Sciences - March 25, 2019 Category: Universities & Medical Training Source Type: news

< i > H. pylori < /i > ( < i > Helicobacter Pylori < /i > ) Infection
Title:H. pylori (Helicobacter Pylori) InfectionCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/20/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 20, 2019 Category: Nutrition Source Type: news

Honey and black cumin found to treat H. Pylori patients
(Natural News) Helicobacter pylori – or H. pylori – infections are fairly common, with more than half the world’s population likely walking around with these bacteria in their gut. Nonetheless, they are responsible for the majority of ulcers of the small intestine and stomach, and are becoming increasingly difficult to treat. New “superbug” type antibiotic-resistant strains... (Source: NaturalNews.com)
Source: NaturalNews.com - March 9, 2019 Category: Consumer Health News Source Type: news

Infection biology: What makes Helicobacter so adaptable?
(Ludwig-Maximilians-Universit ä t M ü nchen) The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - February 12, 2019 Category: Infectious Diseases Source Type: news

Houston Consensus Conference on H. pylori Infection Testing Houston Consensus Conference on H. pylori Infection Testing
This paper presents guidelines for implementing testing for H. pylori infection in U.S. health care systems, with a focus on identifying target populations for diagnosis and therapy.Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 10, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Metformin Tied to Lower Gastric Cancer Risk After H. Pylori Eradication Metformin Tied to Lower Gastric Cancer Risk After H. Pylori Eradication
Metformin use is associated with a lower risk of gastric cancer in diabetic patients after eradication of H. pylori, researchers from Hong Kong report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Mangoes for digestive health: A compound found in the fruit was found to be effective against H. pylori
(Natural News) The next big thing in cancer treatment might just come from a fruit we all know — mangoes. A study published in the African Journal of Traditional, Complementary and Alternative Medicines revealed that mangiferin, a bioactive compound found in mangoes, may reduce the likelihood of gastric cancer induced by the bacteria Helicobacter pylori (H. pylori). In... (Source: NaturalNews.com)
Source: NaturalNews.com - October 27, 2018 Category: Consumer Health News Source Type: news

H. Pylori Antibodies May Point to Colorectal Cancer Risk H. Pylori Antibodies May Point to Colorectal Cancer Risk
Antibodies to Vacuolating cytotoxin A (VacA), one of the major toxins secreted by Helicobacter pylori, show a relationship with colorectal cancer, according to a large study of serum.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - October 23, 2018 Category: Pathology Tags: Gastroenterology News Source Type: news

H. Pylori Ups CRC Risk in Some Ethnic Groups
(MedPage Today) -- And high antibody levels tied to greater incidence in black and Asian patients (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 15, 2018 Category: Gastroenterology Source Type: news

Pilot study identifies strain of bacteria as chief risk factor for stomach cancer
(Fred Hutchinson Cancer Research Center) Researchers at Fred Hutchinson Cancer Research Center have found a specific strain of Helicobacter pylori strongly correlated with stomach cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 12, 2018 Category: International Medicine & Public Health Source Type: news

ASA and Risk of Gastric Cancer After H pylori Eradication ASA and Risk of Gastric Cancer After H pylori Eradication
Does aspirin reduce the risk of gastric cancer in patients with a history of H pylori?Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 31, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

With Three Guidelines on H pylori, What Should Clinicians Do? With Three Guidelines on H pylori, What Should Clinicians Do?
Helicobacter pylori has been the subject of countless recommendations for best practice management. A brief review of some changes reflected in three guidelines is provided to help clinicians.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 29, 2018 Category: Consumer Health News Tags: Gastroenterology Viewpoint Source Type: news

Medical News Today: What are the best natural H. pylori treatments?
The bacteria H. pylori can cause a range of gastrointestinal issues, including gastritis. Infection may even lead to gastric cancer. Fortunately, there are many natural ways to help treat it, including honey, aloe vera, broccoli sprouts, and lemongrass oil. Learn about eight natural treatments for H. pylori here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 31, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Global Resistance to Anti-H. Pylori Drugs Rising (CME/CE)
(MedPage Today) -- Regionally targeted eradication regimens are needed, researchers say (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - July 13, 2018 Category: American Health Source Type: news

Houston Consensus Shrinks Gaps in H. Pylori Management (CME/CE)
(MedPage Today) -- 29 new recommendations to help eliminate active disease especially in at-risk subgroups (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - June 27, 2018 Category: Primary Care Source Type: news

Antibiotic Resistance and Efficacy of Therapy for H. Pylori Antibiotic Resistance and Efficacy of Therapy for H. Pylori
How prevalent is primary resistance to the three antimicrobial agents most commonly used in H. pylori eradication regimens? Is sequential therapy an effective option to improve outcomes?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 26, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Helicobacter Pylori: A Better Test, Low Cure Rates, High Resistance - 3 Studies from DDW
Highlights of H. pylori-focused research at Digestive Disease Week: a noninvasive assessment tool, need for eradication testing, and patterns of treatment resistance.   (Source: ConsultantLive)
Source: ConsultantLive - June 10, 2018 Category: Internal Medicine Authors: Veronica Hackethal, MD Tags: Conferences/Digestive Disease Week Source Type: news

Study: Disease-causing stomach bug attacks energy generation in host cells
(University of Illinois at Urbana-Champaign) Researchers report in a new study that the bacterium Helicobacter pylori -- a major contributor to gastritis, ulcers and stomach cancer -- resists the body's immune defenses by shutting down energy production within the cells of the stomach lining that serve as a barrier to infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 30, 2018 Category: Infectious Diseases Source Type: news

Bacterial manipulation of host cell metabolism
A Helicobacter pylori exotoxin manipulates host cell metabolism by inducing amino acid starvation and inhibiting mTORC1 signaling. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - May 29, 2018 Category: Science Authors: VanHook, A. M. Tags: STKE Editors ' Choice Source Type: news

Durham pharma eyes potential approval of drug in roughly $5B market
RedHill Biopharma (Nasdaq: RDHL) – which continued to grow its U.S. commercial operations based in Raleigh over the course of 2017 – has its sights set on potential approval of a drug in a market worth roughly $5 billion.  RedHill expects to compete enrollment of close to 450 patients in an ongoing Phase III study for its dru g candidate TALICIA for the treatment of H. pylori infection – which can cause chronic gastritis, ulcers and gastric cancer – in the third quarter of this year. As… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - May 7, 2018 Category: Biotechnology Authors: Jennifer Henderson Source Type: news

H. Pylori Linked to Atherosclerosis in Healthy People (CME/CE)
(MedPage Today) -- Infected individuals with no history of coronary heart disease had significant subclinical atherosclerosis (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 31, 2018 Category: Cardiology Source Type: news

Consensus Details H pylori Testing, Treatment for US Patients Consensus Details H pylori Testing, Treatment for US Patients
Consensus document outlines who should be tested and treated for H pylori infection to reduce adverse health consequences of long-term infection.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 29, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Orthotics and Heel Pain; Bacteria and Cancer: It's PodMed Double T! (with audio)
(MedPage Today) -- This week's topics include infants with bronchiolitis, orthotics for heel pain, behavioral therapy in dementia, and H. pylori infection in early gastric cancer (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - March 24, 2018 Category: Psychiatry Source Type: news

Treating H. Pylori Cuts Metachronous Cancer Rate
(MedPage Today) -- 50% reduction in endoscopically resected gastric cancer (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 22, 2018 Category: Gastroenterology Source Type: news

H pylori Eradication Benefits Patients With Early Gastric Cancer H pylori Eradication Benefits Patients With Early Gastric Cancer
Patients with early gastric cancer treated for Helicobacter pylori had a lower incidence of metachronous gastric cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 21, 2018 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Exalenz Bioscience’s BreathID(R) Hp and BreathID Hp Lab Systems Receive FDA Clearance for Diagnosis of Helicobacter pylori Testing in Pediatric Patients
Important new testing option for an infection that impacts nearly 20 million U.S. children and may have significant negative impacts on long-term health MODI'IN, Israel and MANASQUAN, N.J., March 13, 2018 -- (Healthcare Sales & Marketing Network) -- Exa... Diagnostics, FDA Exalenz Bioscience, BreathID, Helicobacter pylori, H. pylori (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 13, 2018 Category: Pharmaceuticals Source Type: news

The Proven & Unproven Health Benefits Of Honey
By Sandee LaMotte, CNN (CNN) — Move over, prehistoric bears. Humans have loved honey since the Stone Age. Rock art pictures of honey harvesting, which at first glance look like drawings from A.A. Milne’s Winnie-the-Pooh, date to about 8000 B.C. Beeswax has been found on pottery dating as far back as 7000 B.C., most likely used for waterproofing. The ancient Egyptians offered honey to the gods and then joined the Greeks, Romans and Chinese in using it as a salve for wounds and a treatment for fevers and stomach ailments. Today, proponents of honey tout its miraculous healing properties, claiming that it can prev...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 20, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Honey Source Type: news

< i > H. pylori < /i > ( < i > Helicobacter Pylori < /i > ) Infection Symptoms, Test, Treatment
Title:H. pylori (Helicobacter Pylori ) Infection Symptoms, Test, TreatmentCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 1/9/2018 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - January 9, 2018 Category: Nutrition Source Type: news

H. Pylori Eludes Immune Response Via Cholesterol Depletion H. Pylori Eludes Immune Response Via Cholesterol Depletion
Manipulation of cell cholesterol levels allows Helicobacter pylori to escape full elimination by host immunity, according to German researchers.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 2, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Illusions Regarding H. pylori Trials and Treatment Guidelines Illusions Regarding H. pylori Trials and Treatment Guidelines
In this commentary, the author points out major flaws in treatment studies and meta-analyses pertaining to H. pylori eradication therapy. Are we overlooking the most important detail?Gut (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 14, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Gastric cancer: A new strategy used by Helicobacter pylori to target mitochondria
(Institut Pasteur) Scientists from the Institut Pasteur and CNRS have recently identified new strategies used by Helicobacter pylori bacteria to infect cells. By specifically targeting mitochondria these bacteria, despite being extracellular, can optimize infection in the host. These findings pave the way for new strategies to combat H. pylori infection, which is associated with most cases of gastric cancer and several other gastric disorders. The results were published on Nov. 21 in the journal Scientific Reports. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 28, 2017 Category: Cancer & Oncology Source Type: news

The Global Recurrence Rate of Helicobacter Pylori The Global Recurrence Rate of Helicobacter Pylori
Is the recurrence rate following H. pylori eradication therapy associated with socioeconomic and sanitary conditions?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 24, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Shape-shifting agent targets harmful bacteria in the stomach
(University of Illinois at Urbana-Champaign) A new shape-shifting polymer can target and kill Helicobacter pylori bacteria in the stomach without killing helpful bacteria in the gut. Such a treatment could improve the digestive health of billions of people worldwide who contract H. pylori infections. The antimicrobial agent morphs into a bacterial hole-puncher in the stomach's acidic environment and reverts to an amorphous, inactive structure when it reaches the higher pH environment of the small intestine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2017 Category: International Medicine & Public Health Source Type: news

How Helicobacter pylori causes gastric cancer
(University of Erlangen-Nuremberg) Gastric cancer is one of the five most fatal types of cancer. According to the statistics of the World Health Organization about 750,000 patients die each year after developing the disease. The main cause is thought to be the bacterium Helicobacter pylori. Researchers at Friedrich-Alexander-Universit ä t Erlangen-N ü rnberg (FAU) have now identified two mechanisms through which this bacterium can cause gastric cancer. Their findings could result in the development of new therapeutic approaches. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 7, 2017 Category: Cancer & Oncology Source Type: news

Acid reflux drugs linked to increased stomach cancer risk
Conclusion PPIs are commonly used medicines for acid reflux. This may seem like alarming news for the many people in the UK who take them, but it's important to remember that the overall risk of stomach cancer is still very low. This study has several limitations that mean we should be cautious about the results: This type of study can't prove PPIs caused the increased risk of cancer. The increased risk could be down to other factors. Researchers were unable to adjust their figures to take account of some relevant confounding factors, such as alcohol and tobacco use, as these weren't routinely recorded. Almost all the pati...
Source: NHS News Feed - November 1, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

PPI Use After H. pylori Eradication Therapy Tied to Increased Risk for Gastric Cancer (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM Long-term use of proton-pump inhibitors (PPIs) after treatment for Helicobacter pylori infection is associated with increased risk for gastric cancer, according to a … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 1, 2017 Category: Primary Care Source Type: news

Long-term use of PPIs linked to doubling in stomach cancer risk
Risk rose with dose and duration of treatment after H pylori eradication Related items fromOnMedica Proton pump inhibitors associated with raised mortality Oesophageal and stomach cancer linked to early adulthood overweight Experts link alcohol to stomach cancer (Source: OnMedica Latest News)
Source: OnMedica Latest News - November 1, 2017 Category: UK Health Source Type: news

Heartburn Drugs Tied to Stomach Cancer Risk
After treatment for H. pylori infection, people who took proton pump inhibitors were at increased risk of stomach cancer. (Source: NYT Health)
Source: NYT Health - November 1, 2017 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Stomach Cancer Ulcers Heartburn Bacteria Helicobacter Pylori (Bacterium) Source Type: news

Gastric Cancer Risk Doubled With Long-term PPI Use Gastric Cancer Risk Doubled With Long-term PPI Use
The risk for gastric cancer increases with the dose and duration of proton-pump inhibitor use after successful H pylori eradication.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Long-term PPI Use Tied to Doubled Risk for Gastric Cancer Long-term PPI Use Tied to Doubled Risk for Gastric Cancer
The risk for gastric cancer increases with the dose and duration of proton-pump inhibitor use after successful H pylori eradication.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 31, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news