Helicobacter pylori impacts the expression of immune checkpoint molecules in gastric cancer via up-regulating SERPINE1
Asian J Surg. 2024 Apr 22:S1015-9584(24)00728-0. doi: 10.1016/j.asjsur.2024.04.068. Online ahead of print.NO ABSTRACTPMID:38653693 | DOI:10.1016/j.asjsur.2024.04.068 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 23, 2024 Category: Surgery Authors: Qijia Zhang Ze Yu Ling Hu Source Type: research
Short-term trends in gastric cancer incidence after insurance coverage expansion for Helicobacter pylori eradication in Japan
Eur J Intern Med. 2024 Apr 22:S0953-6205(24)00170-5. doi: 10.1016/j.ejim.2024.04.010. Online ahead of print.NO ABSTRACTPMID:38653632 | DOI:10.1016/j.ejim.2024.04.010 (Source: European Journal of Internal Medicine)
Source: European Journal of Internal Medicine - April 23, 2024 Category: Internal Medicine Authors: Yusaku Kajihara Source Type: research
Cancers, Vol. 16, Pages 1617: Interaction of Colorectal Neoplasm Risk Factors and Association with Metabolic Health Status Focusing on Normal Waist-to-Hip Ratio in Adults
Conclusions: An increase in FRS and HbA1c or a positive H. pylori infection still warrants vigilance for colorectal adenoma risk when WHR is 0.9. These factors interacted with each other and were found to have a minimal decline in adenoma risk when considering the interaction between WHR and FRS. (Source: Cancers)
Source: Cancers - April 23, 2024 Category: Cancer & Oncology Authors: Ying-Chun Lin Hung-Ju Ko Lo-Yip Yu Ming-Jen Chen Horng-Yuan Wang Shou-Chuan Shih Chuan-Chuan Liu Yang-Che Kuo Kuang-Chun Hu Tags: Article Source Type: research
Causal relationships of Helicobacter pylori and related gastrointestinal diseases on Type 2 diabetes: Univariable and Multivariable Mendelian randomization
ConclusionOur study found that H. pylori IgG antibody, H. pylori GroEL antibody, gastroduodenal ulcer and chronic gastritis are all related to t T2DM, and blood glucose level and obesity mediate the development of H. pylori GroEL antibody and gastroduodenal ulcer on T2DM, respectively. These findings may inform new prevention and intervention strategies for T2DM. (Source: PLoS One)
Source: PLoS One - April 23, 2024 Category: Biomedical Science Authors: Mei Sun Source Type: research
Cancers, Vol. 16, Pages 1611: An Overview of the Spices Used for the Prevention and Potential Treatment of Gastric Cancer
We present the potential molecular mechanisms responsible for the effectivity of a given seasoning substance and their impact on GC cells. We discuss their potential effects on proliferation, apoptosis, and migration. For most of the spices discussed, we also outline the unavailability and side effects of their use. (Source: Cancers)
Source: Cancers - April 22, 2024 Category: Cancer & Oncology Authors: Katarzyna Kostelecka Łukasz Bryliński Olga Komar Justyna Michalczyk Agata Mi łosz Jan Bi łogras Filip Woli ński Alicja Forma Jacek Baj Tags: Review Source Type: research
The trends of pediatric duodenal ulcer and predictors of recurrence
CONCLUSIONS: Hp-positive DU seems to wane. Patients with male sex, lower Hb level, or perforation at diagnosis carried a higher risk of recurrence, which may warrant active surveillance and endoscopic follow-up.PMID:38644127 | DOI:10.1016/j.jfma.2024.04.011 (Source: J Formos Med Assoc)
Source: J Formos Med Assoc - April 21, 2024 Category: General Medicine Authors: Pai-Jui Yeh Chien-Chang Chen Hsun-Chin Chao Jin-Yao Lai Yung-Ching Ming Mi-Chi Chen Ming-Wei Lai Source Type: research
Association Between Helicobacter pylori and Laryngopharyngeal Reflux Disease: A Systematic Review and Meta-Analysis
It is controversial that Helicobacter pylori (H pylori) is involved in the pathogenesis or development of laryngopharyngeal reflux disease (LPRD). (Source: Journal of Voice)
Source: Journal of Voice - April 21, 2024 Category: ENT & OMF Authors: Siwei Liu, Changjiang Li, Siyan Xu, Yanan Guo, Huajie Luo Source Type: research
Unveiling the gastric microbiota: implications for gastric carcinogenesis, immune responses, and clinical prospects
High-throughput sequencing has ushered in a paradigm shift in gastric microbiota, breaking the stereotype that the stomach is hostile to microorganisms beyond H. pylori. Recent attention directed toward the compo... (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - April 19, 2024 Category: Cancer & Oncology Authors: Zhiyi Liu, Dachuan Zhang and Siyu Chen Tags: Review Source Type: research
Retraction Note: Gastroprotective effect of desmosdumotin C isolated from Mitrella kentii against ethanol-induced gastric mucosal hemorrhage in rats: possible involvement of glutathione, heat-shock protein-70, sulfhydryl compounds, nitric oxide, and anti-Helicobacter pylori activity
(Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - April 19, 2024 Category: Complementary Medicine Authors: Heyam Mohamed Ali Sidahmed, Ainnul Hamidah Syahadah Azizan, Syam Mohan, Mahmood Ameen Abdulla, Siddig Ibrahim Abdelwahab, Manal Mohamed Elhassan Taha, A. Hamid A. Hadi, Kamal Aziz Ketuly, Najihah Mohd Hashim, Mun Fai Loke and Jamuna Vadivelu Tags: Retraction Note Source Type: research
GSE250438 Role of the TRIF-IFN-I pathway in Helicobacter-induced gastric cancer progression in an accelerated murine disease model
In this study, we found that H. felis-induced inflammation in Myd88-/- mice progressed to high-grade dysplasia, driven by activation of the type I interferon (IFN-I) signaling pathway and upregulation of its downstream targets, IFN-stimulated genes (ISGs). We also observed enrichment of IFN stimulated-response element (ISRE) motifs in the promoters of upregulated genes, further supporting the involvement of this pathway. In contrast, mice deficient in Toll/interleukin-1 receptor (TIR)-domain-containing adaptor inducing interferon- β (TRIF, TrifLps2) did not progress to severe gastric pathology after H. felis infection, im...
Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
(Re)-definition of the holo- and apo-Fur direct regulons of Helicobacter pylori
J Mol Biol. 2024 Apr 14:168573. doi: 10.1016/j.jmb.2024.168573. Online ahead of print.ABSTRACTIron homeostasis is a critical process for living organisms because this metal is an essential co-factor for fundamental biochemical activities, like energy production and detoxification, albeit its excess quickly leads to cell intoxication. The protein Fur (ferric uptake regulator) controls iron homeostasis in bacteria by switching from its apo- to holo-form as a function of the cytoplasmic level of ferrous ions, thereby modulating gene expression. The Helicobacter pylori HpFur protein has the rare ability to operate as a transcr...
Source: Mol Biol Cell - April 16, 2024 Category: Molecular Biology Authors: Andrea Vannini Eva Pinatel Paolo Emidio Costantini Simone Pelliciari Davide Roncarati Simone Puccio Gianluca De Bellis Vincenzo Scarlato Clelia Peano Alberto Danielli Source Type: research
Rapid and multi-target genotyping of Helicobacter pylori with digital microfluidics
Biosens Bioelectron. 2024 Apr 11;256:116282. doi: 10.1016/j.bios.2024.116282. Online ahead of print.ABSTRACTHelicobacter pylori (H. pylori) infection correlates closely with gastric diseases such as gastritis, ulcers, and cancer, influencing more than half of the world's population. Establishing a rapid, precise, and automated platform for H. pylori diagnosis is an urgent clinical need and would significantly benefit therapeutic intervention. Recombinase polymerase amplification (RPA)-CRISPR recently emerged as a promising molecular diagnostic assay due to its rapid detection capability, high specificity, and mild reaction...
Source: Biosensors and Bioelectronics - April 16, 2024 Category: Biotechnology Authors: Jinsong Liu Rongxin Fu Shuailong Zhang Jialu Hou Hanbin Ma Siyi Hu Hang Li Yanli Zhang Weian Wang Bokang Qiao Baisheng Zang Xun Min Feng Zhang Jie Du Shengkai Yan Source Type: research
Rapid and multi-target genotyping of Helicobacter pylori with digital microfluidics
Biosens Bioelectron. 2024 Apr 11;256:116282. doi: 10.1016/j.bios.2024.116282. Online ahead of print.ABSTRACTHelicobacter pylori (H. pylori) infection correlates closely with gastric diseases such as gastritis, ulcers, and cancer, influencing more than half of the world's population. Establishing a rapid, precise, and automated platform for H. pylori diagnosis is an urgent clinical need and would significantly benefit therapeutic intervention. Recombinase polymerase amplification (RPA)-CRISPR recently emerged as a promising molecular diagnostic assay due to its rapid detection capability, high specificity, and mild reaction...
Source: Biosensors and Bioelectronics - April 16, 2024 Category: Biotechnology Authors: Jinsong Liu Rongxin Fu Shuailong Zhang Jialu Hou Hanbin Ma Siyi Hu Hang Li Yanli Zhang Weian Wang Bokang Qiao Baisheng Zang Xun Min Feng Zhang Jie Du Shengkai Yan Source Type: research
Effect of concurrent infection of Helicobacter pylori with Toxoplasma gondii infection on gastric pathology
Toxoplasma gondii (T. gondii) and Helicobacter pylori (H. pylori) are among the most prevalent foodborne parasitic and bacterial infections worldwide. However, the concurrent impact of coinfection on gastric path... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 16, 2024 Category: Infectious Diseases Authors: Marwa A. Gouda, Sara A. Saied, Ahmed Edrees, Rasha Galal Mostafa, Ashraf Elfert, Aya Abdallah seleem, Asmaa Shams and Sameh Afify Tags: Research Source Type: research
Characterization of the unique oral microbiome of children harboring < em > Helicobacter pylori < /em > in the oral cavity
CONCLUSION: These results suggest unique oral microbiome characteristics in children with H. pylori infection in the oral cavity.PMID:38617439 | PMC:PMC11011227 | DOI:10.1080/20002297.2024.2339158 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - April 15, 2024 Category: Microbiology Authors: Yuko Ogaya Tamami Kadota Masakazu Hamada Ryota Nomura Kazuhiko Nakano Source Type: research
