Ultrasound May ID Children at Risk for Cystic Fibrosis Liver Disease
A heterogeneous liver pattern could indicate a higher risk for advanced cystic fibrosis liver disease (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 21, 2020 Category: Respiratory Medicine Tags: Family Medicine, Gastroenterology, Pathology, Pediatrics, Pulmonology, Radiology, Journal, Source Type: news

Ultrasound May ID Children at Risk for Cystic Fibrosis Liver Disease
THURSDAY, Feb. 20, 2020 -- A heterogeneous pattern on ultrasound examination of the liver may help identify children with cystic fibrosis (CF) at increased risk for developing advanced CF liver disease, according to a study published online Feb. 12... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 20, 2020 Category: Pharmaceuticals Source Type: news

Ultrasound identifies kids at risk of CF liver disease
Ultrasound can help clinicians identify children with cystic fibrosis (CF)...Read more on AuntMinnie.comRelated Reading: Carbon nanotube tomosynthesis may be better for cystic fibrosis Novel MRI scans could aid in cystic fibrosis CT can replace x-ray for pediatric cystic fibrosis patients Growing radiation dose for CF patients highlights risks MRI still no match for CT in cystic fibrosis (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 18, 2020 Category: Radiology Source Type: news

Researchers find test to ID children at higher risk for cystic fibrosis liver disease
(University of Colorado Anschutz Medical Campus) A major multi-center investigation of children with cystic fibrosis has identified a test that allows earlier identification of those at risk for cystic fibrosis liver disease. The study, which includes 11 clinical sites in North America, was led by Michael Narkewicz, MD, professor of pediatrics from the University of Colorado School of Medicine and Children's Hospital Colorado. The findings of the study are published today ahead of print in The Journal of Pediatrics. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 12, 2020 Category: International Medicine & Public Health Source Type: news

Targeting chronic infections and deadly bacteria
(University of Houston) University of Houston engineering professor Mehmet Orman is examining the life cycle of stubborn, drug-resistant persister cells in recurrent infections to find a way to destroy them. Scientists believe persister cells cause the recurrence of chronic health issues like airway infections in cystic fibrosis patients, urinary tract infections and tuberculosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 3, 2020 Category: International Medicine & Public Health Source Type: news

Cystic fibrosis drug funding in NZ − have your say
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - February 1, 2020 Category: Drugs & Pharmacology Source Type: news

At last! Cystic Fibrosis crusade poster girl Harriet gets wonder drug
A BEAMING Harriet Corr holds up her first box of life-saving cystic fibrosis pills, after a year of melting hearts in the Daily Express. (Source: Daily Express - Health)
Source: Daily Express - Health - January 24, 2020 Category: Consumer Health News Source Type: news

Cystic fibrosis campaign: Six young sufferers finally get wonder pills in NHS deal
SIX young cystic fibrosis sufferers get their hands on boxes of lifesaving pills at last after fighting in our crusade to win an NHS deal. Last year, all six spoke out in separate, tear-jerking Daily Express stories to plead for the medications produced by US firm Vertex. (Source: Daily Express - Health)
Source: Daily Express - Health - January 20, 2020 Category: Consumer Health News Source Type: news

Cystic Fibrosis victory: Ayden, 13, weeps with joy as he finally gets miracle drug
BRAVE cystic fibrosis sufferer Ayden Cochrane wept with joy last night, after we helped him secure the American wonder pill that could save his life. In a dramatic change of heart, drug maker Vertex contacted the Daily Express directly, telling us Ayden, 13, will receive Trikafta in the next 24 hours. (Source: Daily Express - Health)
Source: Daily Express - Health - January 19, 2020 Category: Consumer Health News Source Type: news

Novel Drug Candidate Aims To Tackle Superbug Infections In Cystic Fibrosis Patients
What makes the Antabio ’s molecule candidate so unique is that it’s not an antibiotic. Antibiotics typically work by killing bacteria, whereas this molecule aims to disable the bacteria, making it less able to attack and inflame the lungs. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 17, 2020 Category: Pharmaceuticals Authors: Dana Dovey, Contributor Source Type: news

Cystic fibrosis-sufferer, 13, feared to have DAYS left to live as drug giant fails to act
THE MOTHER of stricken 13-year-old Ayden Cochrane last night made a desperate appeal for drugs bosses to save her son ’s life by giving him access to a wonder pill. (Source: Daily Express - Health)
Source: Daily Express - Health - January 17, 2020 Category: Consumer Health News Source Type: news

Correcting airways in cystic fibrosis
(Source: ScienceNOW)
Source: ScienceNOW - January 16, 2020 Category: Science Authors: Alderton, G. Tags: twil Source Type: news

US FDA clears NuvoAir's connected spirometer device
The Air Next is designed for patients with respiratory conditions such as asthma, COPD and cystic fibrosis. (Source: mobihealthnews)
Source: mobihealthnews - January 9, 2020 Category: Information Technology Source Type: news

Swedish startup NuvoAir inks partnership with Roche Italy
The companies want to help people living with cystic fibrosis.   (Source: mobihealthnews)
Source: mobihealthnews - January 3, 2020 Category: Information Technology Source Type: news

Girl, four, with life-limiting cystic fibrosis gets a 'wonder drug' in time for Christmas
Ayda Louden's family, from Carlisle, Cumbria, spent years calling for NHS access to Orkambi. It was finally approved in October. She didn't receive a dose until two weeks ago. (Source: the Mail online | Health)
Source: the Mail online | Health - December 27, 2019 Category: Consumer Health News Source Type: news

Rare cystic fibrosis mutations limit the benefits of targeted drugs
Mutations leading to cystic fibrosis in Latino patients may create treatment disparities, say School scientists (Source: UCSF School of Pharmacy News)
Source: UCSF School of Pharmacy News - December 27, 2019 Category: Universities & Medical Training Source Type: news

Cystic Fibrosis boy gets new drug after NHS discount deal
Negotiations with US pharmaceutical company means that some 5,000 NHS patients will benefit Related items fromOnMedica Drug firm urged to cut £100,000 price of cystic fibrosis drug Life-changing cystic fibrosis drug cost 'should be lowered' Health-focused line on drugs misuse would save lives and money TB could be cured by four months ’ treatment in many patients Statins of small and uncertain benefit in primary prevention (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 24, 2019 Category: UK Health Source Type: news

Cystic fibrosis boy from Hull gets new drug after campaign
Seven-year-old Olly can now get Orkambi after the NHS struck a deal with the manufacturer. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - December 23, 2019 Category: Consumer Health News Source Type: news

'The day I found out that I will likely outlive my children'
Sharon Stepaniuk learned on the same day her oldest and youngest have cystic fibrosis. She hopes she can make a difference for them, and for others in Canada living with CF. (Source: CBC | Health)
Source: CBC | Health - December 22, 2019 Category: Consumer Health News Tags: News/Canada/Edmonton Source Type: news

'We can't wait': Life-saving cystic fibrosis drugs hard to access, advocates say
Hundreds of Albertans sent letters to Health Minister Tyler Shandro earlier this month, calling on the province to make cystic fibrosis drugs more accessible, and to support the development of a federal strategy on rare diseases. (Source: CBC | Health)
Source: CBC | Health - December 22, 2019 Category: Consumer Health News Tags: News/Canada/Edmonton Source Type: news

Family of cystic fibrosis sufferer, 28, issue a desperate plea to the NHS and drug firms
The only real hope of Nicole Adams, 28, from Belfast, lies in a new medicine that can dramatically improve lung function - but the pill is not yet approved for NHS patients. (Source: the Mail online | Health)
Source: the Mail online | Health - December 22, 2019 Category: Consumer Health News Source Type: news

Diagnostic markers for allergic bronchopulmonary aspergillosis in paediatric cystic fibrosis patients
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 20, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

Do climate changes influence environmental aspergillus fumigatus load at the manchester university nhs foundation trust adult cystic fibrosis centre?
DO CLIMATE CHANGES INFLUENCE ENVIRONMENTAL ASPERGILLUS FUMIGATUS LOAD AT THE MANCHESTER UNIVERSITY NHS FOUNDATION TRUST ADULT CYSTIC FIBROSIS CENTRE?Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 16, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

The influence of the cftr modulator ivacaftor on aspergillosis in cystic fibrosis
THE INFLUENCE OF THE CFTR MODULATOR IVACAFTOR ON ASPERGILLOSIS IN CYSTIC FIBROSISConference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - December 16, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

Modifier gene may explain why some with cystic fibrosis are less prone to infection
(University of California - San Diego) People with cystic fibrosis who carry genetic variants that lowerRNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn't fully functional, it's better than none, and may explain why some with cystic fibrosis are less prone to infection than others. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 10, 2019 Category: Biology Source Type: news

Help cystic fibrosis sufferers survive the dangers of winter
WINTER is the hardest time of year for cystic fibrosis sufferers, a charity has revealed. (Source: Daily Express - Health)
Source: Daily Express - Health - December 8, 2019 Category: Consumer Health News Source Type: news

New tool for rapidly analyzing CRISPR edits reveals frequent production of unintended edits
(Burness) Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 6, 2019 Category: Biology Source Type: news

New approach to treating CF reduces inflammation
‘First step’ to better outcomes for cystic fibrosis Related items fromOnMedica Lung experts call for ‘national plan for lung cancer’ Smokers ’ lungs should remain as transplant option COPD patients need better tailored care Antibiotic fails to improve lung function in children with CF Sweet and fruity e-cigs linked to prolonged teenage vaping (Source: OnMedica Latest News)
Source: OnMedica Latest News - December 3, 2019 Category: UK Health Source Type: news

Elexacaftor Helpful in Cystic Fibrosis Patients Homozygous for F508del Elexacaftor Helpful in Cystic Fibrosis Patients Homozygous for F508del
Elexacaftor, in combination with tezacaftor and ivacaftor, improved outcomes in patients with cystic fibrosis (CF) homozygous for the F508del mutation, in a phase 3 trial.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 28, 2019 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Could synthetic molecules provide a general treatment for Cystic Fibrosis?
A new treatment for lung disease in cystic fibrosis (CF) for which there remains no cure could potentially benefit all patients, according to a University of Bristol study published in Chemical Science. The findings are an important step towards a new therapy addressing the fundamental cause of cystic fibrosis. (Source: University of Bristol news)
Source: University of Bristol news - November 14, 2019 Category: Universities & Medical Training Tags: Health, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Physiology, Pharmacology and Neuroscience, Faculty of Science, Faculty of Science, School of Chemistry; Press Release Source Type: news

Vertex deal with Wales expands cystic fibrosis treatment coverage to all of UK
Vertex Pharmaceuticals Inc's drugs for lung condition cystic fibrosis will now be available to patients across the UK after the company reached a pricing deal with Wales on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - November 13, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Study reveals 'bug wars' that take place in cystic fibrosis
(eLife) Scientists have revealed how common respiratory bugs that cause serious infections in people with cystic fibrosis interact together, according to a new study in eLife. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 12, 2019 Category: Infectious Diseases Source Type: news

Bionic pancreas may help control blood sugar levels
According to study published in theJournal of Cystic Fibrosis, a bionic pancreas with a glucose monitoring system, linked to a smart phone app, may help control blood sugar levels in cystic fibrosis-related diabetes.Speciality Medical Dialogues (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 11, 2019 Category: Endocrinology Source Type: news

Use of the basophil surface marker CD203c in the diagnosis of fungal sensitization in patients with cystic fibrosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - November 9, 2019 Category: Respiratory Medicine Authors: MeganB Source Type: news

Drug Trio Could Give Patients With Cystic Fibrosis a New Option
Title: Drug Trio Could Give Patients With Cystic Fibrosis a New OptionCategory: Health NewsCreated: 11/1/2019 12:00:00 AMLast Editorial Review: 11/4/2019 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - November 4, 2019 Category: Respiratory Medicine Source Type: news

Passage: A therapy for cystic fibrosis
It happened this past week: word of a new drug therapy that offers hope to the roughly 30,000 Americans who suffer from cystic fibrosis. Jane Pauley reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 3, 2019 Category: Consumer Health News Source Type: news

Elexacaftor - Tezacaftor - Ivacaftor Efficacious for Cystic Fibrosis
Percentage of FEV1 higher at four weeks and through 24 weeks with treatment versus placebo (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 1, 2019 Category: Respiratory Medicine Tags: Internal Medicine, Critical Care, Pediatrics, Pharmacy, Pulmonology, Conference News, Source Type: news

Drug Trio Could Give Patients With Cystic Fibrosis a New Option
(Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - November 1, 2019 Category: Respiratory Medicine Tags: Pharmacy, Pulmonology, Research, News, Source Type: news

Hope for cystic fibrosis patients as three-drug trial 'significantly' improves lung function
The treatment, called trikafta, targets the gene responsible for the life-threatening disorder in around 90 per cent of patients. The US regulator FDA approved the drugs after the major study. (Source: the Mail online | Health)
Source: the Mail online | Health - November 1, 2019 Category: Consumer Health News Source Type: news

Drug Trio Could Give Patients With Cystic Fibrosis a New Option
FRIDAY, Nov. 1, 2019 -- A three-drug combo that significantly improves lung function in cystic fibrosis patients could benefit 90% of people with the life-threatening disease, a new study suggests. It included patients with a single copy of the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 1, 2019 Category: General Medicine Source Type: news

Elexacaftor-Tezacaftor-Ivacaftor Efficacious for Cystic Fibrosis
FRIDAY, Nov. 1, 2019 -- For patients with cystic fibrosis with Phe508del-minimal function genotypes, elexacaftor-tezacaftor-ivacaftor, which was recently approved by the U.S. Food and Drug Administration, is efficacious, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 1, 2019 Category: Pharmaceuticals Source Type: news

Glutathione May Benefit Lung Function in Cystic Fibrosis Glutathione May Benefit Lung Function in Cystic Fibrosis
Inhaled and oral glutathione may benefit lung function in patients with cystic fibrosis (CF), although vitamin and mineral antioxidant supplementation does not appear to have a positive treatment effect, an updated Cochrane Review reveals.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - November 1, 2019 Category: Allergy & Immunology Tags: Pulmonary Medicine News Source Type: news

Monthly News Roundup - October 2019
Breakthrough Drug Trikafta Approved for 90% of Cystic Fibrosis Patients In October, Trikafta (elexacaftor/tezacaftor/ivacaftor tablets; ivacaftor tablets) was approved by the U.S. Food and Drug Administration (FDA) for cystic fibrosis (CF) patients... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 1, 2019 Category: Pharmaceuticals Source Type: news

Studies Yield ‘Impressive’ Results in Fight Against Cystic Fibrosis
The findings hold promise for a vast majority of those with cystic fibrosis, according to the director of the National Institutes of Health. “This should be a cause for major celebration,” he wrote. (Source: NYT Health)
Source: NYT Health - October 31, 2019 Category: Consumer Health News Authors: Niraj Chokshi Tags: Cystic Fibrosis Drugs (Pharmaceuticals) Trikafta Vertex Pharmaceuticals Therapy and Rehabilitation Genetics and Heredity Source Type: news

Long-awaited cystic fibrosis drug could turn deadly disease into a manageable condition
Thirty years after scientists discovered the defective gene that causes cystic fibrosis, two new trials show a therapy could help 90 percent of patients. The FDA approved the triple drug, Trikafta, five months ahead of its deadline. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - October 31, 2019 Category: Consumer Health News Authors: Carolyn Y. Johnson Source Type: news

Vertex, NHS England finally agree on Orkambi price
The National Health Service in England has finally approved Vertex's Orkambi to treat people with cystic fibrosis, after four years of deadlock over the price tag. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - October 25, 2019 Category: Pharmaceuticals Source Type: news

Girl's joy over news about cystic fibrosis drug Orkambi
The moment Isabelle Finn's mum shares the news has been watched thousands of times on social media. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 25, 2019 Category: Consumer Health News Source Type: news

NHS England finally secures deal on cystic fibrosis drugs
Manufacturer has agreed to drop price and submit to NICE appraisal; drugs will be available within 30 days Related items fromOnMedica Life-changing cystic fibrosis drug cost 'should be lowered' Home office gives go-ahead to medicinal cannabis prescriptions Drug firm urged to cut £100,000 price of cystic fibrosis drug Promise to end new HIV transmissions in England by 2030 Remedy quest (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 25, 2019 Category: UK Health Source Type: news

NHS England concludes wide-ranging deal for cystic fibrosis drugs
NHS England has announced it has secured a definitive agreement with Vertex Pharmaceuticals to make available all three of their UK-licensed cystic fibrosis medicines. (Source: NHS Networks)
Source: NHS Networks - October 25, 2019 Category: UK Health Source Type: news

FDA Approves New Cystic Fibrosis Drug
The treatment, Trikafta, increases lung function in most patients with the disease—but comes with a hefty price tag. (Source: The Scientist)
Source: The Scientist - October 24, 2019 Category: Science Tags: News & Opinion Source Type: news