How Long Can You Live With Cystic Fibrosis?
Title: How Long Can You Live With Cystic Fibrosis?Category: Diseases and ConditionsCreated: 9/16/2020 12:00:00 AMLast Editorial Review: 9/16/2020 12:00:00 AM (Source: MedicineNet Womens Health General)
Source: MedicineNet Womens Health General - September 16, 2020 Category: OBGYN Source Type: news

Combination antimicrobial susceptibility testing for acute exacerbations in chronic infection of Pseudomonas aeruginosa in cystic fibrosis
Current evidence, limited to one RCT (n=132), is insufficient to determine effect of choosing antibiotics based on combination antimicrobial susceptibility testing vs conventional antimicrobial susceptibility testing. Further investigation is required. This is an updated version of a previously published review. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 15, 2020 Category: Consumer Health News Source Type: news

New method of detecting illnesses including coronavirus and cystic fibrosis
(University of Leeds) A new and quicker method of diagnosing diseases in patients has been created by researchers. The team has developed a system of examining individual molecules to detect the presence of disease in blood. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 2, 2020 Category: Infectious Diseases Source Type: news

Ivacaftor not cost effective in cystic fibrosis with G551D mutation
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - September 1, 2020 Category: Drugs & Pharmacology Source Type: news

Delayed access to cystic fibrosis drug could result in preventable death: study
(Source: St. Michael's Hospital News and Media)
Source: St. Michael's Hospital News and Media - August 24, 2020 Category: Hospital Management Tags: Hospital News Source Type: news

Landmark NHS deal to open up access to life-changing cystic fibrosis drug
NHS patients will be among the first in Europe to be prescribed Kaftrio, which significantly improves lung function, helping people with cystic fibrosis to breathe more easily and enhancing their overall quality of life. (Source: NHS Networks)
Source: NHS Networks - August 24, 2020 Category: UK Health Source Type: news

Allergen-specific igG4 response to recombinant aspergillus fumigatus allergens in patients with non-cystic fibrosis bronchiectasis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Heel-prick blood test could predict type 1 diabetes in children
Heel-prick tests are already used in Britain to check for nine rare but serious conditions, including cystic fibrosis and sickle cell disease. Scientists are pushing for diabetes to be added. (Source: the Mail online | Health)
Source: the Mail online | Health - August 10, 2020 Category: Consumer Health News Source Type: news

Boston Hospitals To Test Cystic Fibrosis Drug On Severely Ill Coronavirus Patients
BOSTON (CBS) — Harvard University researchers are working with two Boston hospitals to try a new way to help the sickest coronavirus patients. Boston Children’s Hospital and Brigham and Women’s Hospital will test a drug approved by the FDA to treat people with cystic fibrosis on those experiencing severe COVID-19 pneumonia and respiratory failure. The drug is called Dornase alfa, also known as DNase 1 or Pulmozyme, and it works to prevent lung infections by breaking up thick mucus. That may make oxygen easier to deliver via ventilator, researchers say. There’s also hope that the drug might break up ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 7, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Syndicated CBSN Boston Syndicated Local Boston Children's Hospital Brigham and Women's Hospital Coronavirus Harvard University Source Type: news

Randomized study for treatment of COVID pneumonia uses cystic fibrosis drug dornase alfa
(Boston Children's Hospital) Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation. The study aims to enroll 60 adults and children (over age 3) admitted to intensive care units. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 28, 2020 Category: International Medicine & Public Health Source Type: news

GlycoNet invests $3.9 million to address research gaps in Canadian healthcare
(Canadian Glycomics Network) The Canadian Glycomics Network (GlycoNet) today awarded $3.9 million in grant funding to 11 collaborative research projects. The fund will support a wide range of multidisciplinary research teams across 17 Canadian research institutions and their industry partners to address unmet medical needs in cancer, gastrointestinal inflammations, cystic fibrosis, Sanfillipo disease, Parkinson's, and autoimmune diseases. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 23, 2020 Category: Cancer & Oncology Source Type: news

CFHealthHub for managing cystic fibrosis during the COVID-19 pandemic - Medtech innovation briefing (MIB219), NICE (published 10th July 2020)
CFHealthHub is a digital platform to help adults with cystic fibrosis manage their condition and monitor their medicine use. Evidence from a randomised feasibility study and two economic studies is discussed; the results of a UK RCT (n=607) are due for publication later this year (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 13, 2020 Category: Consumer Health News Source Type: news

Cystic fibrosis: why so many respiratory complications?
(Universit é de Gen è ve) Cystic fibrosis, one of the most common genetic diseases in Switzerland, causes severe respiratory and digestive disorders. Despite considerable therapeutic advances, this disease still reduces life expectancy, in particular due to life-threatening respiratory infections. Scientists from the University of Geneva (UNIGE) have discovered the reason for this large number of lung infections: a protein, Vav3. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 13, 2020 Category: International Medicine & Public Health Source Type: news

BARNEY CALMAN: Cystic fibrosis sufferers finally get 'wonder drug' after endless talks
Over the past six months, the MoS has lifted the lid on the secretive talks between NHS England and drug company Vertex on access to cystic fibrosis drugs. (Source: the Mail online | Health)
Source: the Mail online | Health - July 4, 2020 Category: Consumer Health News Source Type: news

NHS England secures deal for triple therapy for cystic fibrosis
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - July 1, 2020 Category: Drugs & Pharmacology Source Type: news

Cystic fibrosis patients offered 'life-transforming' drug
The three-drug combination, Kaftrio, will now be available on the NHS in England. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - June 30, 2020 Category: Consumer Health News Source Type: news

NHS to seal the deal on miracle cystic fibrosis medicine
Anthony Usher lost his brother Elliott, pictured together, last year and now his own health his faltering, but there is hope after a 'Holy Grail' drug was given the green light by the safety regulator. (Source: the Mail online | Health)
Source: the Mail online | Health - June 27, 2020 Category: Consumer Health News Source Type: news

Mycobiome-microbiome cross-talk analysis during acute pulmonary exacerbation: focus on climax-attack model in cystic fibrosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 24, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Bronchodilator Response in Cystic Fibrosis Patients Diagnosed with Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Presence of Fungal Species in Sputum of Adult Patients with Cystic Fibrosis Is Associated with Pseudomonas Spp. Colonization, Frequent Exacerbations, Inhaled Antibiotic and Steroid Use Single Center Experience
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 21, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Miracle cystic fibrosis drug which has been dubbed the 'holy grail' could be free on NHS next month
Six months ago, Nicole Adams (pictured) was in intensive care at Belfast City Hospital and critically ill with cystic fibrosis. Within hours of taking her first dose of Trikafta, she began to feel different. (Source: the Mail online | Health)
Source: the Mail online | Health - June 21, 2020 Category: Consumer Health News Source Type: news

She Struggled With Asthma, but It Had Never Been This Bad
She had trouble breathing, and the E.R. doctors discovered a mass in her lung. Was this cancer — or something a little more unusual? (Source: NYT Health)
Source: NYT Health - June 17, 2020 Category: Consumer Health News Authors: Lisa Sanders, M.D. Tags: Cystic Fibrosis Coronavirus (2019-nCoV) Senses and Sensation Lungs Hospitals Pneumonia Smoking and Tobacco Source Type: news

Children With Cystic Fibrosis Caregivers Face Sleep Difficulties Children With Cystic Fibrosis Caregivers Face Sleep Difficulties
Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 15, 2020 Category: Consumer Health News Tags: Pulmonary Medicine News Source Type: news

Insmed Receives FDA Breakthrough Therapy Designation for Brensocatib in Patients with Non-Cystic Fibrosis Bronchiectasis (NCFBE)
Full Results from Phase 2 WILLOW Study of Brensocatib in NCFBE to be Presented at Virtual ATS Session on June 24, 2020 BRIDGEWATER, N.J., June 8, 2020 -- (Healthcare Sales & Marketing Network) -- Insmed Incorporated (Nasdaq:INSM), a global biopharmaceu... Biopharmaceuticals, FDA Insmed, brensocatib, bronchiectasis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 8, 2020 Category: Pharmaceuticals Source Type: news

Cystic Fibrosis sufferers will be among first to benefit from NHS home test kits
A NEW handheld testing kit will allow thousands of shielding cystic fibrosis patients to check their health at home. The genetic lung condition means Britain's 10,500 sufferers are particularly vulnerable to COVID-19. Normally when they catch a lung bug they must travel to their local hospital's CF unit for tests and face-to-face consultation. (Source: Daily Express - Health)
Source: Daily Express - Health - June 8, 2020 Category: Consumer Health News Source Type: news

A newly discovered disease may lead to better treatment of cystic fibrosis
(University of M ü nster) Cystic fibrosis is the most frequent severe inherited disorder worldwide. Researchers have now discovered a novel disease that might lead to a better understanding of cystic fibrosis and new treatment options in the future. The results have been published in the scientific journal " Journal of Medical Genetics " . (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 5, 2020 Category: International Medicine & Public Health Source Type: news

Atomic blueprint of 'molecular machine' reveals role in membrane protein installation
(Van Andel Research Institute) Van Andel Institute scientists have revealed the first known atomic structure of a 'molecular machine' responsible for installing critical signaling proteins into cellular membranes. The findings, published today in Nature, shed new light on how this process works, and lay the foundation for potential future therapies for diseases like cancer, Alzheimer's and cystic fibrosis. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 3, 2020 Category: Biology Source Type: news

4DMedical's Lung Imaging Technology Receives FDA Clearance as COVID-19 Intensifies Global Focus on Respiratory Health
WOODLAND HILLS, Calif., May 25, 2020 -- (Healthcare Sales & Marketing Network) -- 4DMedical, an Australian medical technology company specializing in medical imaging innovation software, announced today it has received clearance from the U.S. Food & Drug ... Diagnostics, Radiology, FDA 4DMedical, COVID-19, asthma, COPD, cystic fibrosis, lung cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 25, 2020 Category: Pharmaceuticals Source Type: news

Spirovant Sciences Appoints Roland Kolbeck, PhD, as Chief Scientific Officer
MedImmune R&D veteran delivers 20+ years of experience in respiratory sciences and drug discovery PHILADELPHIA, May 13, 2020 -- (Healthcare Sales & Marketing Network) -- Spirovant Sciences, a gene therapy company developing treatments and cures for gen... Biopharmaceuticals, Personnel Spirovant Sciences, gene therapy, cystic fibrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - May 13, 2020 Category: Pharmaceuticals Source Type: news

Frightened workers self-isolating to protect vulnerable loved ones shouldn ’t be punished
The government must do more to protect key workers threatened with dismissal or put on unpaid leave if they’re off work self-isolating because of vulnerable relatives, says UNISON today (Wednesday). Anxious staff have come to UNISON with heartbreaking stories, terrified that if forced to go into work, they might take the virus home – with potentially devastating consequences. Local government and NHS employers have put agreements in place to protect the income of any staff off work because of the health of family members. But some employers – including councils and schools – are instead using Public...
Source: UNISON Health care news - May 6, 2020 Category: UK Health Authors: Anthony Barnes Tags: News Press release coronavirus dave prentis sick pay Source Type: news

Pulmonary Complications of Cystic Fibrosis Pulmonary Complications of Cystic Fibrosis
A new review provides insight into the pathophysiology, risk factors, and management of pulmonary complications associated with cystic fibrosis.Seminars in Respiratory and Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 4, 2020 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Vertex sets higher 2020 revenue target due to ‘remarkable’ CF drug sales
While other companies are tempering or staying mum on annual sales forecasts amid the COVID-19 pandemic, booming sales of its new cystic fibrosis drug have led Vertex to increase its expectations. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - April 30, 2020 Category: Pharmaceuticals Authors: Allison DeAngelis Source Type: news

Vertex sets higher 2020 revenue target due to ‘remarkable’ CF drug sales
While other companies are tempering or staying mum on annual sales forecasts amid the COVID-19 pandemic, booming sales of its new cystic fibrosis drug have led Vertex to increase its expectations. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - April 30, 2020 Category: Biotechnology Authors: Allison DeAngelis Source Type: news

Diary of isolation: Cystic Fibrosis sufferer reveals life in lockdown
OVER a month into what will now be 14 weeks of shielding at home, I must admit I'm already feeling a bit stir crazy. Having genetic respiratory condition cystic fibrosis, I was already self-isolating before being ordered by the government to stay at home - so I've actually been stuck inside for five weeks. (Source: Daily Express - Health)
Source: Daily Express - Health - April 21, 2020 Category: Consumer Health News Source Type: news

8-Puff Dry-Powder Inhaler Wins Red Dot Product Design Award
Hovione Technology’s 8Shot Dry Powder Inhaler (DPI) has earned the Red Dot 2020 Product Design Award in the Healthcare Daily Living AIDS category. João Ventura Fernandes, PhD, director of technology development and licensing for Hovione Technology Ltd., told MD+DI that 8Shot “was developed to be the world’s first 8-dose, factory-filled dry powder inhaler device enabling effective and safe drug delivery to the lungs of a range of drugs expected to be developed and reach the market during the next years." It is targeted for "delivery of new pharma...
Source: MDDI - April 21, 2020 Category: Medical Devices Authors: Daphne Allen Tags: Design Source Type: news

Keep children from hospital during crisis
(Flinders University) With stressed hospital services, and concerns about the spread of COVID-19, experts are reminding carers of children and young people of the importance of safely adhering to their supported chronic condition self-management plans from the safety of their home. This is particularly vital for chronic conditions of childhood such as asthma, cystic fibrosis, congenital heart disease, diabetes, mental illness, as well as those with experience of childhood cancer or disability (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - April 21, 2020 Category: International Medicine & Public Health Source Type: news

The journey from scientific breakthrough to a life-changing cystic fibrosis drug
For 30 years, a treatment was just around the corner. After setbacks and triumphs, it’s finally here. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 19, 2020 Category: Consumer Health News Authors: Carolyn Y. Johnson Source Type: news

Covid-19 guidelines on cystic fibrosis, COPD and dermatological conditions
NICE has published three new rapid guidelines on the care of patients with and without Covid-19. (Source: NHS Networks)
Source: NHS Networks - April 15, 2020 Category: UK Health Source Type: news

COVID-19 rapid guideline: cystic fibrosis.
The purpose of this guideline is to maximise the safety of patients with cystic fibrosis and make the best use of NHS resources, while protecting staff from infection. It will also enable services to match capacity to patient needs if services become limited because of the COVID-19 pandemic. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 14, 2020 Category: Consumer Health News Source Type: news

COVID-19 rapid guideline: cystic fibrosis: NG 170, NICE
The purpose of this guideline is to maximise the safety of patients with cystic fibrosis and make the best use of NHS resources, while protecting staff from infection. It will also enable services to match capacity to patient needs if services become limited because of the COVID-19 pandemic. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 14, 2020 Category: Consumer Health News Source Type: news

What you need to know if you have a condition that can affect breathing
Yale School of Medicine experts offer critical COVID-19 guidance for people with chronic pulmonary conditions like asthma, COPD, and cystic fibrosis. (Source: Yale Science and Health News)
Source: Yale Science and Health News - April 7, 2020 Category: Universities & Medical Training Source Type: news

Cystic Fibrosis Diagnosis in Newborns, Children, and Adults Cystic Fibrosis Diagnosis in Newborns, Children, and Adults
Learn more about the available diagnostic modalities for the identification of cystic fibrosis across all age groups.Seminars in Respiratory and Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 3, 2020 Category: Consumer Health News Tags: Pulmonary Medicine Journal Article Source Type: news

Drug Trials Snapshots: SYMDEKO
SYMDEKO is a drug for the treatment of cystic fibrosis (CF) in patients 12 years and older, who have specific gene mutations (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 31, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news

5 Live caller 'dancing around days after having coronavirus’
Steve has cystic fibrosis, but says he was up '"dancing around the room" just a few days after having coronavirus. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 19, 2020 Category: Consumer Health News Source Type: news

One doctor ’s story: ‘We don’t have the masks, goggles – or the staff’
A senior consultant at a leading hospital for respiratory conditions such as pneumonia and cystic fibrosis talks to the Observer•Coronavirus – latest updates•See all our coronavirus coverageNHS staff are asking the same questions as everyone else about coronavirus. How deadly is it? How do we protect ourselves? Are the government ’s tactics right? And how will the health service cope when – and it is when – it leaves large numbers of people seriously ill, many fighting for their lives? These questions are even more pressing for us because within two weeks we will be part of the frontline a...
Source: Guardian Unlimited Science - March 15, 2020 Category: Science Authors: Denis Campbell Tags: Coronavirus outbreak Science Infectious diseases World news UK news Source Type: news

New Financing Could Help BillionToOne Expand Product Offerings
BillionToOne wants to expand its diagnostic offerings and its most recent financing could give it a push in that direction. The Menlo Park, CA-based company has raised $15 million in a follow-on to its series A round. With this financing, the company BillionToOne has brought in more than $32.5 million. The private company noted previous investors, Hummingbird Ventures and NeoTribe Ventures led the investment round with participation from Y Combinator, Libertus Capital, Pacific 8 Ventures, Civilization Ventures, 500 Startups Istanbul, and HOF Capital. BillionToOne said it will use the proceeds to support the commercial expa...
Source: MDDI - March 11, 2020 Category: Medical Devices Authors: Omar Ford Tags: IVD Business Source Type: news

FDA grants Breakthrough Therapy Designation for Roche ’s Esbriet (pirfenidone) in unclassifiable interstitial lung disease
Basel, 3 March 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) to Esbriet ® (pirfenidone) for adults with unclassifiable interstitial lung disease (uILD). The designation was granted based on data from a Phase II trial, which studied the efficacy and safety of Esbriet in uILD[1]. The study represented the first randomised controlled trial to exclusively enroll patients with progressive fibrosing uILD.“Today’s milestone for Esbriet builds on our continued commitment to improving the standard of care ...
Source: Roche Investor Update - March 3, 2020 Category: Pharmaceuticals Source Type: news

Cystic Fibrosis miracle drug battle on as NHS refuse treatment approved 11 years ago
THE DAILY Express today demands a miracle drug for a rare genetic condition finally be made available on the NHS, after an agonising 11-year wait. (Source: Daily Express - Health)
Source: Daily Express - Health - February 29, 2020 Category: Consumer Health News Source Type: news

Ultrasound May ID Children at Risk for Cystic Fibrosis Liver Disease
A heterogeneous liver pattern could indicate a higher risk for advanced cystic fibrosis liver disease (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - February 21, 2020 Category: Respiratory Medicine Tags: Family Medicine, Gastroenterology, Pathology, Pediatrics, Pulmonology, Radiology, Journal, Source Type: news

Ultrasound May ID Children at Risk for Cystic Fibrosis Liver Disease
THURSDAY, Feb. 20, 2020 -- A heterogeneous pattern on ultrasound examination of the liver may help identify children with cystic fibrosis (CF) at increased risk for developing advanced CF liver disease, according to a study published online Feb. 12... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 20, 2020 Category: Pharmaceuticals Source Type: news