Duodenoscopes With Disposable Caps Led to Less Microbial Contamination
(MedPage Today) -- Use of duodenoscopes with disposable elevator caps during endoscopic retrograde cholangiopancreatography (ERCP) led to lower rates of contamination following high-level disinfection compared with standard scope designs, and did... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - January 24, 2023 Category: Gastroenterology Source Type: news

New TREMFYA ® (guselkumab) Data Show an Overall Clinical Response Rate of Approximately 80 Percent in a Phase 2b Induction Study of Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2b QUASAR Induction Study 1 in adults with moderately to severely active ulcerative colitis (UC) with inadequate responses to previous treatments. The data presented at the 2022 American College of Gastroenterology (ACG) Annual Scientific Meeting show an overall clinical response rate of approximately 80 percent in patients who were randomized to TREMFYA® (guselkumab).Clinical responsea at weeks 12 or 24 of the study was ultimately achieved by 80.2 percent of patients who w...
Source: Johnson and Johnson - October 24, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Transnasal Endoscopy Tested in Primary Care for Esophageal Screen Transnasal Endoscopy Tested in Primary Care for Esophageal Screen
With a lower price tag and fewer complications than sedated endoscopy, experts said the transnasal approach could help primary care physicians catch potential GI cancers early.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - October 17, 2022 Category: Cancer & Oncology Tags: Gastroenterology News Source Type: news

Results of Novel Clinical Study of Guselkumab and Golimumab Combination Therapy Show Adults with Moderately to Severely Active Ulcerative Colitis Maintained Higher Rates of Clinical, Histologic, and Endoscopic Remission at Week 38
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from an ongoing analysis of a Phase 2a clinical trial showing adults with moderately to severely active ulcerative colitis (UC) who received 12 weeks of combination induction therapy with guselkumab and golimumab, followed by a transition to guselkumab alone for maintenance, achieved a clinical remission ratea (based on the modified Mayo score [mMayo])b at week 38 of 47.9 percent, a higher rate than induction and maintenance treatment with either guselkumab alone (31.0 percent) or golimumab al...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news

Complete Endoscopic Healing in IBD Linked to Lower Relapse Risk
(MedPage Today) -- Patients with inflammatory bowel disease (IBD) have a high risk of relapse after stopping tumor necrosis factor (TNF) inhibitors, but those who achieved complete endoscopic healing had a far lower risk, according to a prospective... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 2, 2022 Category: Gastroenterology Source Type: news

How to Remove Foreign Bodies?
Discussion Living in the world makes the human body susceptible to foreign bodies. Orifices are particularly inviting for children to explore and see how it feels if the opening is touched by their hands or an object. Small objects are easily inserted or even just retained (such as toilet tissue in the genital area, or tissue in the nose). The mouth is particularly inviting to explore objects with as oral sensations are paramount to survival even at birth. Food can be considered a foreign body and often acts like one when stuck in the respiratory or gastrointestinal tract but is necessary to sustain life. When someone says...
Source: PediatricEducation.org - July 4, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen Presents Study Results Showing Clinical Efficacy for TREMFYA ® (guselkumab) and Long-Term Safety Profile for STELARA® (ustekinumab) for Patients Living with Inflammatory Bowel Disease at Digestive Disease Week® 2022
SPRING HOUSE, PENNSYLVANIA, May 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2 GALAXI 1 clinical trial of TREMFYA® (guselkumab) in adult patients with moderately to severely active Crohn’s disease (CD), and from three separate long-term pooled analyses of adult patients with ulcerative colitis (UC) and CD treated with STELARA® (ustekinumab).1,2,3,4 These data are being presented as oral and poster presentations and are among 29 Janssen abstracts presented during the Digestive Disease Week® (DDW) meeting taking place in person and virtually in San Di...
Source: Johnson and Johnson - May 24, 2022 Category: Pharmaceuticals Source Type: news

Noninvasive Esophageal Cancer Screening May Reach More Patients Noninvasive Esophageal Cancer Screening May Reach More Patients
Noninvasive approaches have lower sensitivity and specificity than endoscopic screening, but greater access could make them cost effective.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 10, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Colonoscopy Before Age 50 May Cut Colorectal Cancer Risk in Women
MONDAY, May 9, 2022 -- Initiation of lower gastrointestinal endoscopy before 50 years of age is associated with a reduced risk for colorectal cancer (CRC) in women, according to a study published online May 5 in JAMA Oncology. Wenjie Ma, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 9, 2022 Category: Pharmaceuticals Source Type: news

Real-World Evidence Supports Earlier Colorectal Cancer Screening Real-World Evidence Supports Earlier Colorectal Cancer Screening
Starting lower GI endoscopy before age 50 was associated with a significantly reduced risk of CRC, providing strong support for the updated CRC screening recommendations.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 5, 2022 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

Endoscopic Obesity Treatments Offer Alternative to Surgery Endoscopic Obesity Treatments Offer Alternative to Surgery
While these methods have shown lower efficacy, they are associated with fewer adverse effects.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 27, 2022 Category: Endocrinology Tags: Gastroenterology News Source Type: news

Endoscopic Drainage Better for Necrotizing Pancreatitis
MONDAY, April 25, 2022 -- For patients with necrotizing pancreatitis, the rate of fistula formation and mortality is lower with endoscopic drainage (ED) than with other surgical drainage methods, according to a systematic review and meta-analysis... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 25, 2022 Category: Pharmaceuticals Source Type: news

The Truth About Common Digestive Health Fears
Everyone experiences digestive problems now and then, and they’re nobody’s idea of a good time. In a survey of nearly 72,000 adults in the U.S., 61% reported having had at least one gastrointestinal (GI) symptom over the previous week, and within that group, 58% said they’d had two or more GI symptoms over the past week, according to a study in a 2018 issue of the American Journal of Gastroenterology. Because symptoms like constipation, heartburn, and abdominal pain are generally vague and often don’t have an obvious cause, those suffering tend to fear the worst. “People get very concerned abo...
Source: TIME: Health - March 14, 2022 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized healthscienceclimate Source Type: news

What Are Common Gastrointestinal Polyposes in Children?
Discussion Bloody stools or blood in the diaper is a relatively common complaint in general pediatrics. For most patients it is often a minor concern. Commonly it is a transient problem (e.g. rectal fissure caused by constipation or trauma) or often not blood (e.g. urate crystals in the diaper, food, menses, etc.). Real blood does occur with an identifiable cause such as long distance running or heavy exercise, or milk protein allergy/sensitivity that improves with a milk-restricted diet. Many more serious causes are associated with heavier or more recalcitrant bleeding, increased defecation, abdominal pain, poor eating an...
Source: PediatricEducation.org - January 24, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Janssen Reports Positive Topline Week 48 Phase 2 Results for TREMFYA ® (guselkumab) in Adults With Moderately to Severely Active Crohn's Disease
SPRING HOUSE, PENNSYLVANIA, November 17, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced topline results from the Phase 2 GALAXI 1 clinical trial which showed rates of clinical remission (Crohn’s Disease Activity Index [CDAI]<150) previously reported at week 12 increased at week 48 among adults with moderately to severely active Crohn’s disease (CD) treated with TREMFYA® (guselkumab).1 At week 48, 65 percent of patients receiving TREMFYA achieved clinical remission. TREMFYA is under investigation and not currently approved for the treatment of CD in the U.S.2Janssen previously...
Source: Johnson and Johnson - November 17, 2021 Category: Pharmaceuticals Source Type: news