Optical Technologies Unreliable at Diagnosing Pre-Cancerous Colorectal Polyps Optical Technologies Unreliable at Diagnosing Pre-Cancerous Colorectal Polyps
The accuracy of optical technologies in differentiating cancerous from benign tissue is"insufficient" for most routine clinical applications, including diagnosing pre-cancerous colorectal polyps, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 15, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Study: Adenomas Tend to Be Missed With Colonoscopy (CME/CE)
(MedPage Today) -- Meta-analysis finds high miss rates for advanced and flat adenomas, serrated polyps (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 5, 2019 Category: Gastroenterology Source Type: news

A Pill, That ’s a Device, That Delivers a Drug!
Rani Therapeutics just achieved one of its most significant milestones since it was spun out of InCube Lab in 2012. The San Jose, CA-based company just finished conducting the first human study of its “robotic capsule” set to replace injections. Previously the device, which administers a pharmaceutical through a digestible pill, had been tested in more than 100 animal models. The human study was conducted at a Clinical Research Organization (CRO) in Texas under the Investigational Review Board (IRB) approval. There were two sub-groups, one cohort was fed and another fasted. Each subject ...
Source: MDDI - February 28, 2019 Category: Medical Devices Authors: Omar Ford Tags: Implants Source Type: news

Breathing Problems From Aspirin? Help is Here
(MedPage Today) -- Encouraging results with desensitization protocol, nasal polyp removal (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - February 26, 2019 Category: Allergy & Immunology Source Type: news

Trial Shows Biologic's Efficacy in Sinusitis With Polyps
(MedPage Today) -- Reduced need for surgery, systemic steroids (Source: MedPage Today Allergy)
Source: MedPage Today Allergy - February 25, 2019 Category: Allergy & Immunology Source Type: news

Check-Cap ’ s cancer screening capsule will have U.S. study
Check-Cap (NSDQ:CHEK) said its X-ray-enabled, colorectal cancer-screening capsule will have a pilot study in the United States. The Isfiya, Israel-based startup makes the C-Scan System, an ingestible capsule used to detect precancerous polyps without the need for laxatives or an invasive procedure. The C-Scan system uses an ultra-low dose X-ray capsule, an integrated positioning, control, and recording system, and proprietary software to generate a 3D map of the inner lining of the colon. It received approval from Israel’s Ministry of Health Medical Device division (AMAR) and the CE Mark...
Source: Mass Device - February 12, 2019 Category: Medical Devices Authors: Nancy Crotti Tags: Blog Clinical Trials Implants News Well Oncology Research & Development Check-Cap FDA New York University Source Type: news

Aspirin Underused for Advanced Colorectal Polyps
Only 42.6 percent of 84 patients with biopsy - proven advanced colorectal polyps were taking aspirin (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 12, 2019 Category: Cancer & Oncology Tags: Family Medicine, Geriatrics, Gastroenterology, Internal Medicine, Oncology, Pharmacy, Journal, Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
Low-dose aspirin can lower your risk for colon cancer but fewer than half the people who already have polyps aren’t taking it. (Source: WebMD Health)
Source: WebMD Health - February 12, 2019 Category: Consumer Health News Source Type: news

Aspirin Underused for Advanced Colorectal Polyps
TUESDAY, Feb. 12, 2019 -- Aspirin is underused to reduce the risk for colorectal cancer among patients with advanced colorectal polyps, according to a study recently published in The American Journal of Medicine. Noting that the U.S. Preventive... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 12, 2019 Category: Pharmaceuticals Source Type: news

Aspirin Can Help Prevent Colon Cancer, But Many at Risk Don't Take It
MONDAY, Feb. 11, 2019 -- People with colon polyps spotted during screening are at higher risk for colon cancer. But while low-dose aspirin could lower the odds for the disease, too few patients adopt the regimen, new research shows. Advanced colon... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 11, 2019 Category: General Medicine Source Type: news

Aspirin to prevent colon cancer underutilized in high-risk patients
(Florida Atlantic University) The US Preventive Services Task Force (USPSTF) concluded that aspirin reduces the risk of colorectal cancer by 40 percent as well as recurrence of advanced polyps, which are a major risk factor. To explore whether high risk patients are adhering to USPSTF guidelines, FAU researchers analyzed data from structured interviews with 84 patients and found that less than half (42.9 percent) reported taking aspirin. These findings pose major challenges that require multifactorial approaches by physicians and patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 7, 2019 Category: Cancer & Oncology Source Type: news

Is chronic rhinosinusitis associated with increased risk of depression, anxiety?
This study of about 49,000 people   in a   South Korean insurance database examined the risk of depression and anxiety in chronic rhinosinusitis and depending on the type of chronic rhinosinusitis (with or without nasal polyps). (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice
(Bentham Science Publishers) Recent epidemiological and experimental studies have shown that obesity is a major risk factor for Colorectal Cancer (CRC). Regular intake of high fat-containing diet can promote obesity and metabolic syndrome by increasing the insulin resistance and inflammatory response which contribute to carcinogenesis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 18, 2019 Category: Cancer & Oncology Source Type: news

Pseudopolyps Not Associated With Greater Colorectal Cancer Risk Pseudopolyps Not Associated With Greater Colorectal Cancer Risk
Post-inflammatory polyps (PIPs) are not associated with colorectal neoplasia (CRN) in patients with inflammatory bowel disease (IBD), according to new findings.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 20, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Significance, Detection, and Management of Serrated Polyps Significance, Detection, and Management of Serrated Polyps
When might serrated polyps have malignant potential? Review the diagnostic challenges and management recommendations for these lesions in this overview.Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 17, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Post-Inflammatory Polyps Not Linked to Colorectal Neoplasia
FRIDAY, Dec. 14, 2018 -- For patients with inflammatory bowel disease (IBD), post-inflammatory polyps (PIPs) are associated with greater severity and extent of colon inflammation and higher rates of colectomy, but not with development of colorectal... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 14, 2018 Category: Pharmaceuticals Source Type: news

Living With Cancer: When can you stop colon cancer screening?
Colon cancer screening: At what age can you stop? People older than 75 who have been getting regular colon cancer screening since age 50 and who have had consistently negative screenings ? no polyps or colon cancer, and who are not at an increased risk of colon cancer because of family history, may not need [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 14, 2018 Category: Databases & Libraries Source Type: news

Colorectal Cancer Screening Pill to Be in US Pilot Study
Check-Cap is getting one step closer to having its capsule-based screening method for colorectal cancer on the U.S. market. The Isfiya, Israel-based company has received FDA conditional approval for an IDE to initiate a pilot study of the C-Scan capsule. FDA’s conditional approval of the IDE requires Check-Cap to provide additional information to the agency and the company may begin enrolling patients immediately upon approval by the study site's Institutional Review Board (IRB). The trial will consist of up to 45 patients and it will be a single-arm study. Patients who are enrolled will be those conside...
Source: MDDI - December 14, 2018 Category: Medical Devices Authors: Omar Ford Tags: Regulatory and Compliance Implants Source Type: news

Check-Cap wins conditional IDE approval for C-Scan pilot study
Check-Cap (NSDQ:CHEK) said today it won conditional approval from the FDA for its investigational device exemption application to launch a pilot study of its C-Scan system. The Israel-based company’s C-Scan system is designed as an alternative to standard colon cancer screening methods. The system uses an ingestible, ultra-low dose X-ray capsule and a wireless tracking system to return structural information on the lumen of the colon to create 2D and 3D maps. The conditional approval will require Check-Cap to provide additional information to the FDA, but will allow the company to being enrolling patients immedi...
Source: Mass Device - December 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diagnostics Food & Drug Administration (FDA) Check-Cap Source Type: news

Loss of tight junction protein promotes development of precancerous cells
(Beth Israel Deaconess Medical Center) BIDMC researchers demonstrated that the lack of claudin 18 prompted the development of precancerous, abnormal cells and polyps in the engineered mouse model. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 12, 2018 Category: Cancer & Oncology Source Type: news

Wendy Atkin obituary
Epidemiologist whose research led to a breakthrough in bowel cancer screening programmes worldwide“Breakthrough” is an overused word when applied to medical advances. But in the case of the2010 trial of a new screening test for bowel cancer led by Wendy Atkin, professor of gastrointestinal epidemiology atImperial College London, who has died of acute myeloid leukaemia aged 71, it is fully deserved. Its impact will be felt by millions. The trial was the first in the world to show that bowel cancer – the second biggest cancer killer in the UK – could be prevented with a simple, five-minute test.The ex...
Source: Guardian Unlimited Science - November 29, 2018 Category: Science Authors: Ara Darzi Tags: Cancer research Health Medical research Science Source Type: news

Many Patients With Polyps Delay Follow-up Colonoscopy: Study
Title: Many Patients With Polyps Delay Follow-up Colonoscopy: StudyCategory: Health NewsCreated: 11/26/2018 12:00:00 AMLast Editorial Review: 11/27/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - November 27, 2018 Category: Cancer & Oncology Source Type: news

Many With Polyps Delay Follow-Up Colonoscopy
People whose colonoscopies find adenomas – polyps that can become cancer -- are routinely asked to come back for another colonoscopy in three years, but a surprisingly high percentage fail to get the follow-up, a new study reports. (Source: WebMD Health)
Source: WebMD Health - November 26, 2018 Category: Consumer Health News Source Type: news

Many Patients With Polyps Delay Follow - up Colonoscopy: Study
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 26, 2018 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Preventive Medicine, News, Source Type: news

Former Candidate for Governor Settles Wrongful Death Suit; More Former Candidate for Governor Settles Wrongful Death Suit; More
Emergency custody orders trigger a horrific tragedy; untreated polyp leads to patient's death and a lawsuit; high court weighs survivor damages for deceased plaintiff.Medscape Business of Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 26, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care Article Source Type: news

Many Patients With Polyps Delay Follow-up Colonoscopy: Study
MONDAY, Nov. 26, 2018 -- Many people found to have colon polyps (adenomas) that can lead to cancer don't have follow-up colonoscopies at recommended times, a new study finds. Patients who have certain types of adenomas, or large or numerous ones,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 26, 2018 Category: General Medicine Source Type: news

Many Patients With Polyps Delay Follow-up Colonoscopy: Study
(Source: Cancercompass News: Colorectal Cancer)
Source: Cancercompass News: Colorectal Cancer - November 26, 2018 Category: Cancer & Oncology Source Type: news

Aspirin and omega-3 reduce pre-cancerous bowel polyps
Both aspirin and a purified omega-3, called EPA, reduce the number of pre-cancerous polyps in patients found to be at high risk of developing bowel cancer, according to new research. A clinical trial, led by the University of Leeds, found that both aspirin and EPA reduced the number of bowel polyps in patients one year on from a screening colonoscopy (large bowel camera test), although they did not reduce the chances of an individual having any polyps present in the bowel. (Source: World Pharma News)
Source: World Pharma News - November 20, 2018 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Treating a rare genetic disorder that causes colon cancer in children
(University of Houston) A University of Houston pharmaceutical scientist is developing a new drug that recycles through the colon to treat children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds -- if not thousands -- of colorectal polyps. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 20, 2018 Category: Cancer & Oncology Source Type: news

Aspirin and omega-3 reduce pre-cancerous bowel polyps
(University of Leeds) Both aspirin and a purified omega-3, called EPA, reduce the number of pre-cancerous polyps in patients found to be at high risk of developing bowel cancer, according to new research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 19, 2018 Category: Cancer & Oncology Source Type: news

Artificial intelligence could help doctors identify hard-to-spot colon polyps
Colon cancer is the second leading cause of cancer-related deaths in the U.S. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 10, 2018 Category: Consumer Health News Source Type: news

How AI could help doctors identify hard-to-spot colon polyps
"Colon cancer is the second-leading cause of cancer-related deaths in the U.S. but colonoscopies have been found to reduce the risk of death from the disease by 70 percent or more by detecting cancer early. But doctors don ’t always find every polyp. As a gastroenterologist, CBS News chief medical correspondent Dr. Jon LaPook knows all too well that colon polyps can be tough to spot. But a new high-tech tool may be able to help doctors spot them. " (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - November 10, 2018 Category: Consumer Health News Source Type: news

Precision medicine is not enough: Moving towards precision surveillance
(Regenstrief Institute) The interval at which an individual undergoes a repeat colonoscopy because of previous pre-cancerous polyps -- a practice known as 'surveillance' -- should be tailored to the individual and not simply be determined by the results of prior colonoscopies, according to Regenstrief Institute research scientist Thomas Imperiale, M.D. In a American Journal of Gastroenterology editorial he calls for 'precision surveillance,' a phrase he has coined to echo the personalized, targeted focus of precision medicine and application of these concepts to colon cancer screening and surveillance. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 7, 2018 Category: Cancer & Oncology Source Type: news

Higher CRC Risks in Black Americans Not Related to Biology Higher CRC Risks in Black Americans Not Related to Biology
The overall prevalence of advanced, precancerous polyps does not differ with race, but uniform screening guidelines could still leave many at increased risk for colorectal cancer (CRC).Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 6, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Racial differences in colorectal cancer incidence not due to biology
(Regenstrief Institute) A systematic review and meta-analysis from the Regenstrief Institute and Indiana University School of Medicine has found that, in spite of the higher incidence and death rate of colorectal cancer in blacks, no difference exists in the overall prevalence of advanced, precancerous polyps between average-risk blacks and whites who underwent a screening colonoscopy. These findings suggest that the age at which to begin screening need not differ based on race, provided all other factors -- access to screening, in particular -- are similar. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 23, 2018 Category: Cancer & Oncology Source Type: news

AI colonoscopies may produce smarter results, doctors say
New test uses artificial intelligence to spot polyps, where all colorectal cancers begin. Doctors hope the technology will help save lives. CBS News' Chris Martinez reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - October 18, 2018 Category: Consumer Health News Source Type: news

AI colonoscopies may produce smarter results, save lives, doctors say
New test uses artificial intelligence to spot polyps, where all colorectal cancers begin. CBS News' Chris Martinez reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - October 18, 2018 Category: Consumer Health News Source Type: news

Doctors Using Artificial Intelligence To Make Colonoscopies More Accurate
BOSTON (CBS) – Colon cancer is the second leading cause of cancer death in the United States and now doctors in California are using artificial intelligence to make colonoscopies more accurate and help save lives. AI colonoscopies would not replace routine colonoscopies, which most people need to get every 10 years starting at age 45 or 50 depending on whom you ask, but this new technology can help doctors identify polyps that they might otherwise miss. Polyps are growths that can turn into cancer but if removed early can prevent cancer from growing. The artificial intelligence uses an algorithm, analyzing 98 images ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - October 17, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated Local Watch Listen AI colonoscopy Cancer Dr. Mallika Marshall Source Type: news

Nine ways research could save the NHS money
This highlight provides nine treatments and initiatives that are cost effective for the NHS including weight loss surgery, misaligned shoulder fractures, rotavirus vaccine, public health interventions, oxygen levels for acute bronchiolitis in children, routine replacement of intravenous cannulae, behavioural activation, oral surgery in primary care, and uterine polyps. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 16, 2018 Category: Consumer Health News Source Type: news

ACG: Focus on the Practical at Annual Meeting
(MedPage Today) -- Topics will range from gluten contamination to artificial intelligence for polyp detection (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - October 5, 2018 Category: Gastroenterology Source Type: news

Check-Cap touts interim post-CE Mark C-Scan study results
Check-Cap (NSDQ:CHEK) today released interim results from the post-CE Mark approval study of its C-Scan system version 3, touting the device’s ability to detect polyps in un-prepped colons. The Israel-based company’s C-Scan system is designed as an alternative to standard colon cancer screening methods. The system uses an ingestible, ultra-low dose X-ray capsule and a wireless tracking system to return structural information on the lumen of the colon to create 2D and 3D maps. The study aimed to assess the safety and clinical performance of the C-Scan system version 3 in detecting polyps, Check-cap said. Da...
Source: Mass Device - September 4, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diagnostics Oncology Check-Cap Source Type: news

Computer - Aided Colonoscopy Reliably Identifies Small Polyps
Diagnosing, but leaving these polyps can save time and, likely, costs (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 27, 2018 Category: Cancer & Oncology Tags: Gastroenterology, Internal Medicine, Oncology, Journal, Source Type: news

Computer-Aided Colonoscopy Reliably Identifies Small Polyps
MONDAY, Aug. 27, 2018 -- Computer-aided colonoscopy can reliably diagnose small polyps that do not need to be removed, according to a study published online Aug. 14 in the Annals of Internal Medicine. Yuichi Mori, M.D., Ph.D., from the Showa... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 27, 2018 Category: Pharmaceuticals Source Type: news

A deep look at nasal polyps offers insights into allergic diseases
(Brigham and Women's Hospital) Investigators from Brigham and Women's Hospital, along with collaborators from the Broad Institute and MIT, have used some of the most advanced sequencing technology to peer into nasal polyps, gleaning new insights not only into this condition but also the severe form of inflammation that may lead to other disorders, such as asthma, allergic rhinitis and allergic eczema. The team's findings are published Aug. 22, 2018 online in Nature. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 22, 2018 Category: International Medicine & Public Health Source Type: news

A Deep Look at Nasal Polyps Offers Insights into Allergic Diseases
Using advanced sequencing technology, investigators find dramatically altered cells and other clues about inflammatory diseases (Source: BWH News)
Source: BWH News - August 22, 2018 Category: Hospital Management Source Type: news

Medical News Today: What to do about vaginal cysts, sores, and bumps
A lump or bump on the vagina may have a variety of causes. Causes can include cysts, warts, polyps, and, rarely, vaginal cancer. Treatment depends on the cause and may involve medication, lifestyle and hygiene changes, or even surgery. Learn more about the causes and treatment options of lumps on the vagina here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 15, 2018 Category: Consumer Health News Tags: Women's Health / Gynecology Source Type: news

Targeting Inflammation Slows STK11 Mutation-Driven Polyp Growth
A study shows that LKB1 deficiency in T cells increases gastrointestinal polyposis development. (Source: CancerNetwork)
Source: CancerNetwork - August 14, 2018 Category: Cancer & Oncology Authors: Bryant Furlow Source Type: news

AI Improves Colonoscopy Diagnostics in Prospective Trial AI Improves Colonoscopy Diagnostics in Prospective Trial
Artificial intelligence performs extremely well in the diagnosis of diminutive nonneoplastic polyps in the distal colon, allowing endoscopists to safely diagnose them and leave them alone.Medscape Medical Ethics (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 14, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

AI Permits Diagnose-and-Leave Plan for Small Polyps
(MedPage Today) -- Real-time CAD endocytoscopy had pathologic prediction rate of 98.1%, with a negative predictive value of up to 96.4 (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 13, 2018 Category: Primary Care Source Type: news

Inside Hologic ’ s evolving definition of women ’ s healthcare
Hologic (NSDQ:HOLX), known in the medtech industry for its mammography and diagnostics devices, is rethinking what it means to be a women’s healthcare company. The 6,000-person company wants to expand its reach to include products that care for women’s well-being, as well as their health – a concept that Dr. Edward Evantash honed when he led the Ob/Gyn division at Tufts Medical Center. “The beauty of being an Ob/Gyn is that you really take care of women throughout the continuum of their lifecycle,” Evantash, Hologic’s medical director & VP of global medical affairs, told MassDev...
Source: Mass Device - August 13, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Business/Financial News Food & Drug Administration (FDA) Women's Health Cynosure Inc. Hologic Source Type: news