Newly discovered immune cell type may be key to improving pancreatic cancer immunotherapy
(Memorial Sloan Kettering Cancer Center) Current immunotherapies don't work for most people with cancer. Researchers have identified an overlooked immune cell type that may react to targeted therapies to rally a more powerful immune response in more cancer patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 20, 2020 Category: Cancer & Oncology Source Type: news

Mechanosensing metabolically moves cancer cells
A stiff stroma triggers metabolic changes that support invasion and metastasis in pancreatic cancer cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 18, 2020 Category: Science Authors: Wong, W. Tags: STKE Editors ' Choice Source Type: news

Pancreatic cancer 'time machine' exposes plot twist in cell growth and invasion
(Purdue University) A pancreatic cancer 'time machine' engineered by Purdue University researchers has revealed that the disease is even more unpredictable than previously thought: cancer cells promote each other's invasiveness when they grow together. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 17, 2020 Category: Cancer & Oncology Source Type: news

ASTRO nabs VA contract to create quality indicators
The U.S. Department of Veterans Affairs (VA) has awarded a one-year contract...Read more on AuntMinnie.comRelated Reading: ASTRO names new editor in chief for clinical journal ASTRO issues rad therapy guidelines for skin cancer ASTRO, ACR update RT practice parameters ASTRO wants changes to CMS payment proposal ASTRO updates guidance on pancreatic cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - February 13, 2020 Category: Radiology Source Type: news

Rush earns National Center of Excellence for Pancreatic Cancer designation
(Rush University Medical Center) The National Pancreatic Foundation's National Center of Excellence for Pancreatic Cancer designation is earned by hospitals that demonstrate the multi-disciplinary approach, social support and advanced research resources needed to treat this devastating disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 13, 2020 Category: Cancer & Oncology Source Type: news

Bright idea in dentist's office leads to innovative smoking cessation project
Results from this study recently published online in Addiction found primary care physicians providing smokers with a free, two week starter kit of nicotine replacement therapy (NRT) increased quit attempts While sitting in the dentist's office, Hollings Cancer Center researcher Matthew Carpenter, Ph.D., of the Medical University of South Carolina, had a bright idea. As he received his goody bag with dental hygiene products, he wondered why not conduct a study and have primary care providers do the same thing for their patients who use tobacco. The bags would contain educational material, free lozenges and tobacco cessati...
Source: Dental Technology Blog - February 12, 2020 Category: Dentistry Source Type: news

Foot-and-mouth-disease 'could help treat pancreatic CANCER'
A protein from the foot-and-mouth disease virus, which causes mouth blisters and a fever in animals, was developed into a drug to target pancreatic cancer by Queen Mary University. (Source: the Mail online | Health)
Source: the Mail online | Health - February 12, 2020 Category: Consumer Health News Source Type: news

Foot-and-mouth-disease virus could help target the deadliest cancer
(Pancreatic Cancer Research Fund) The foot-and-mouth-disease virus is helping scientists to tackle a common cancer with the worst survival rate -- pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 11, 2020 Category: Cancer & Oncology Source Type: news

Cedars-Sinai to study how fat may promote cancer spread to liver
(Cedars-Sinai Medical Center) A diagnosis of pancreatic or colon cancer often sparks dread about the disease's likely next destination: the liver. That's because liver metastasis is a leading cause of death in these patients. A Cedars-Sinai scientific team has been awarded a $9.1 million grant by the National Cancer Institute to study this often-fatal process, with the goal of understanding how cancer spreads to the liver and finding ways to block it. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 6, 2020 Category: International Medicine & Public Health Source Type: news

Unprecedented exploration generates most comprehensive map of cancer genomes to date
(University of Melbourne) An international team has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of cancer and signposting new directions for its diagnosis and treatment.Published today in Nature, more than 700 researchers have analysed more than 2600 samples from 38 cancer types ranging from common cancers like colorectal and breast cancers, to rare cancer types including pancreatic and brain cancers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 5, 2020 Category: Cancer & Oncology Source Type: news

Pancreatic cancer symptoms: Signs of the disease to look out for when you go to the toilet
PANCREATIC cancer symptoms don't usually appear in the early stages, making it difficult to diagnose. But to avoid catching the disease in its later stages it's important to recognise any signs when they develop. There are two symptoms to watch out for when you go to the toilet. (Source: Daily Express - Health)
Source: Daily Express - Health - February 3, 2020 Category: Consumer Health News Source Type: news

Bringing the 'sticky' back to pancreatic cancer
(Tohoku University) A multidisciplinary team of researchers at Japan's Tohoku University has found that a gene regulator, called BACH1, facilitates the spread of pancreatic cancer to other parts of the body. The scientists, who published their findings in the journal Cancer Research, say drugs that control BACH1 could improve disease prognosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 3, 2020 Category: Cancer & Oncology Source Type: news

How to lose visceral fat: Cooking with this oil could help reduce the harmful belly fat
VISCERAL fat is hidden inside the body, cushioning organs such as the liver, pancreas and intestines. Too much of this "active fat" can lead to adverse health effects: it increases the risk of type 2 diabetes, heart disease and cancer. One simple swap in how you cook your food can help to reduce the harmful belly fat. (Source: Daily Express - Health)
Source: Daily Express - Health - February 2, 2020 Category: Consumer Health News Source Type: news

Bluestar Genomics ’ breakthrough study highlights promising data for multi-cancer detection from a single blood draw
(CG Life) Bluestar Genomics published a new study demonstrating the efficacy of their 5-hydroxymethylcytosine (5hmC) signal detection technology for its use in breast, lung, pancreatic, and prostate cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - January 29, 2020 Category: Biology Source Type: news

Does lung damage speed pancreatic cancer?
(Thomas Jefferson University) High levels of CO2 in the body, due to chronic respiratory disorders, may exacerbate pancreatic cancer, making it more aggressive and resistant to therapy. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 29, 2020 Category: Cancer & Oncology Source Type: news

Eileen M. O ’Reilly, MD, on the Challenges of Treating Patients with Pancreatic Cancer
The medical oncologist from Memorial Sloan Kettering Cancer Center discussed challenges in treating patients with pancreatic center, and also the challenge of obtaining effective drugs in the clinical setting. (Source: CancerNetwork)
Source: CancerNetwork - January 27, 2020 Category: Cancer & Oncology Authors: Eileen M. O & #039;Reilly, MD Source Type: news

Pancreatic cancer symptoms: Five signs in your stools that may signal the deadly disease
PANCREATIC cancer is when uncontrollable cells multiply within the pancreas. The large gland is part of the digestive system, and so warning signs of the deadly condition could be flushed away in the toilet bowl. (Source: Daily Express - Health)
Source: Daily Express - Health - January 25, 2020 Category: Consumer Health News Source Type: news

Should cancer centers ban the bell?
Bells have become commonplace within oncology centers as a means to allow cancer...Read more on AuntMinnie.comRelated Reading: ASTRO names new editor in chief for clinical journal ASTRO issues rad therapy guidelines for skin cancer ASTRO, ACR update RT practice parameters ASTRO wants changes to CMS payment proposal ASTRO updates guidance on pancreatic cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 24, 2020 Category: Radiology Source Type: news

Surgeries are being postponed because of a surgical gown shortage
When the patriarch of a Boston-area family was diagnosed with stage 3 pancreatic cancer, the family was told he needed to start treatment immediately. (Source: CNN.com - Health)
Source: CNN.com - Health - January 23, 2020 Category: Consumer Health News Source Type: news

Pulling the plug on calcium pumps -- potential new treatment strategy for pancreatic cancer
(Pancreatic Cancer Research Fund) UK scientists have identified a new way to kill pancreatic cancer cells by 'pulling the plug' on the energy generator that fuels calcium pumps on their cell surface. The study, published in the British Journal of Cancer, reports how switching off the cancer's energy supply causes the pancreatic cancer cells to become 'poisoned' by an irreversible build-up of calcium. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 16, 2020 Category: Cancer & Oncology Source Type: news

Pancreatic cancer symptoms: What colour is your pee? Warning sign of the deadly disease
PANCREATIC cancer symptoms don ’t usually show in the early stages of the disease, but like all cancers, recognising symptoms when they do show can ensure a better chance of survival. Having a certain colour pee is one of the warning signs to look out for. (Source: Daily Express - Health)
Source: Daily Express - Health - January 14, 2020 Category: Consumer Health News Source Type: news

Unique Toronto-based clinical trial reveals new subtypes of advanced pancreatic cancer
(Ontario Institute for Cancer Research) Researchers at the Ontario Institute for Cancer Research (OICR) and the University Health Network (UHN) have discovered detailed new information about the subtypes of pancreatic cancer. A better understanding of the disease groups may lead to new treatment options and improved clinical outcomes for this lethal disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 13, 2020 Category: Cancer & Oncology Source Type: news

Obesity linked to increased risk for cancer
According to a Danish study published in theJournal of International Medicine, obesity may increase the risk of developing common cancers, such as breast and pancreatic, by 12%.News Medical (Source: Society for Endocrinology)
Source: Society for Endocrinology - January 8, 2020 Category: Endocrinology Source Type: news

Pancreatic cancer cells secrete signal that sabotages immune attack on tumors
(NYU Langone Health / NYU School of Medicine) A key immune signal has a previously unknown role in turning off the immune system's attack on pancreatic cancer cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 8, 2020 Category: International Medicine & Public Health Source Type: news

University of Colorado Cancer Center named Pancreas Foundation Center of Excellence
(University of Colorado Anschutz Medical Campus) CU Cancer Center operates on 30+ percent of pancreatic cancer patients, double the national average. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 8, 2020 Category: Cancer & Oncology Source Type: news

Trebek to Lewis: Let's beat pancreatic cancer
Both men are 79 years old and revealed they were diagnosed with stage 4 pancreatic cancer last year. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - January 7, 2020 Category: Consumer Health News Source Type: news

Alex Trebek to Rep. John Lewis: Let's survive cancer in 2020
Alex Trebek has a message of support for U.S. congressman John Lewis as both fight pancreatic cancer. (Source: CBC | Health)
Source: CBC | Health - January 7, 2020 Category: Consumer Health News Tags: News/Entertainment Source Type: news

FDA Approves New Pancreatic Treatment Found To Double Time Patients Live Without Disease Progression
Lynparza works by preventing cells that have been destroyed by chemotherapy from repairing themselves. As a result, cancer progression is slowed. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - January 7, 2020 Category: Pharmaceuticals Authors: Dana Dovey, Contributor Source Type: news

Alex Trebek to Rep. John Lewis: Let ’s Beat Pancreatic Cancer Together
(LOS ANGELES) — Alex Trebek has a message of support for Congressman John Lewis as both fight pancreatic cancer. “We’re starting a new year, and let’s see if we can’t both complete the year as pancreatic cancer survivors,” Trebek said when asked what he would tell Lewis. He noted they’re the same age, 79. The Georgia Democrat and veteran civil rights leader announced his diagnosis of advanced cancer in late December. In making his announcement, Lewis made clear that he has no plans to step aside and said, “I have a fighting chance.” Trebek made his illness public last ...
Source: TIME: Health - January 6, 2020 Category: Consumer Health News Authors: LYNN ELBER / AP Tags: Uncategorized Cancer onetime Television Source Type: news

FDA Approves Drug for Pancreatic Cancer Treatment
Title: FDA Approves Drug for Pancreatic Cancer TreatmentCategory: Health NewsCreated: 1/1/2020 12:00:00 AMLast Editorial Review: 1/2/2020 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - January 2, 2020 Category: Cancer & Oncology Source Type: news

FDA Approves Drug for Pancreatic Cancer Treatment
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 2, 2020 Category: General Medicine Source Type: news

FDA Approves Drug for Pancreatic Cancer Treatment
Olaparib is already approved for use in BRCA-mutated ovarian and breast cancers. (Source: WebMD Health)
Source: WebMD Health - December 31, 2019 Category: Consumer Health News Source Type: news

Lynparza approved in the US as a 1st-line maintenance treatment of germline BRCA-mutated metastatic pancreatic cancer
AstraZeneca and MSD Inc., Kenilworth, N.J., US (MSD: known as Merck & Co., Inc. inside the US and Canada) announced that Lynparza (olaparib) has been approved in the US for the maintenance treatment of adult patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) metastatic pancreatic adenocarcinoma (pancreatic cancer) (Source: World Pharma News)
Source: World Pharma News - December 31, 2019 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

Lynparza (olaparib) Approved in the US as a First-Line Maintenance Treatment of Germline BRCA-Mutated Metastatic Pancreatic Cancer
30 December 2019 -- AstraZeneca and Merck& Co., Inc., Kenilworth, N.J., US (Merck: known as MSD outside the US and Canada) today announced that Lynparza® (olaparib) has been approved in the US for the maintenance treatment of adult patients... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - December 30, 2019 Category: Drugs & Pharmacology Source Type: news

Feds approve drug for treating pancreatic cancer
Health regulators clear AstraZeneca and Merck treatment for disease projected to kill 46,000 Americans this year. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - December 30, 2019 Category: Consumer Health News Source Type: news

Rep. John Lewis to Be Treated for Pancreatic Cancer
The 79-year-old said he was diagnosed during a "routine medical visit and subsequent tests." (Source: WebMD Health)
Source: WebMD Health - December 30, 2019 Category: Consumer Health News Source Type: news

New Option in Pancreatic Cancer: Olaparib for BRCA Mutations New Option in Pancreatic Cancer: Olaparib for BRCA Mutations
The PARP inhibitor olaparib (Lynparza) has been approved by the FDA as maintenance therapy for germline BRCA-mutated pancreatic cancer.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 30, 2019 Category: Consumer Health News Tags: Hematology-Oncology News Alert Source Type: news

AstraZeneca, Merck score win with Lynparza approval for pancreatic cancer
AstraZeneca and Merck's ovarian cancer drug Lynparza has received U.S. regulatory approval for the treatment of advanced pancreatic cancer, cementing its lead in a niche category of cancer treatments. (Source: Reuters: Health)
Source: Reuters: Health - December 30, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Rep. John Lewis Has Stage 4 Pancreatic Cancer, What Does This Mean?
This champion of civil rights and longtime Congressman from Georgia just revealed a very, very tough diagnosis. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 30, 2019 Category: Pharmaceuticals Authors: Bruce Y. Lee, Contributor Source Type: news

FDA Approves First PARP Inhibitor as Frontline Maintenance in Pancreatic Cancer
The FDA approved olaparib for the maintenance treatment of adult patients with germline BRCA-mutated metastatic pancreatic adenocarcinoma. (Source: CancerNetwork)
Source: CancerNetwork - December 30, 2019 Category: Cancer & Oncology Authors: Kristie L. Kahl Source Type: news

Heartbreaking News, Then Tumor Find Leads to Genetic Testing Heartbreaking News, Then Tumor Find Leads to Genetic Testing
The NCCN has updated guidelines for genetic testing for breast, ovarian, and pancreatic cancer, with a new list of high- to moderate-penetrance genes and a new section on pancreatic cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 27, 2019 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

OBI Pharma Granted FDA Orphan Drug Designation for the Treatment of Pancreatic Cancer for Its Antibody-Drug Conjugate (ADC) Targeted Cancer Therapy, OBI-999
First Orphan Drug Designation for OBI-999, a novel first-in-class Antibody-Drug Conjugate targeting Globo H, a glycolipid antigen found on multiple tumor types TAIPEI, Taiwan, Dec. 26, 2019 -- (Healthcare Sales & Marketing Network) -- OBI Pharma, Inc.,... Biopharmaceuticals, Oncology, FDA OBI Pharma, Globo H, Pancreatic Cancer (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 26, 2019 Category: Pharmaceuticals Source Type: news

Top UCLA news stories of 2019
UCLA began observing its 100th birthday this year and delivered new  advances in research, health care, the arts, community service and teaching. These are some of the top stories from UCLA Newsroom in 2019 — those which made news and engaged the community of Bruins and beyond.UCLA Newsroom will resume publishing on Jan. 2, 2020. For more, be sure toperuse the archives and to followUCLA Newsroom on Twitter. UCLA turns 100UCLA ArchiveUCLA from overhead in the 1930s.Founders of UCLA would marvel at their creationIn just 100 years, UCLA has grown into a respected center of learning, research and health ca...
Source: UCLA Newsroom: Health Sciences - December 19, 2019 Category: Universities & Medical Training Source Type: news

Lynparza recommended by FDA advisory committee for 1st-line maintenance treatment of germline BRCA-mutated metastatic pancreatic cancer
AstraZeneca and MSD Inc., Kenilworth, NJ, US (MSD: known as Merck & Co., Inc. inside the US and Canada) announced that the US Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) voted 7 to 5 to recommend Lynparza (olaparib) as a 1st-line maintenance monotherapy for patients with germline BRCA-mutated (gBRCAm) metastatic adenocarcinoma of the pancreas (pancreatic cancer), whose disease has not progressed following 1st-line platinum-based chemotherapy. (Source: World Pharma News)
Source: World Pharma News - December 18, 2019 Category: Pharmaceuticals Tags: Featured AstraZeneca Business and Industry Source Type: news

ODAC Votes in Favor of Olaparib as a First-Line Maintenance Therapy in Metastatic Pancreatic Cancer
The PARP inhibitor was recommended as a first-line maintenance monotherapy for patients with germline BRCA-mutated metastatic pancreatic cancer. (Source: CancerNetwork)
Source: CancerNetwork - December 18, 2019 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

ASTRO issues rad therapy guidelines for skin cancer
The American Society for Radiation Oncology (ASTRO) has released new clinical...Read more on AuntMinnie.comRelated Reading: ASTRO, ACR update RT practice parameters ASTRO wants changes to CMS payment proposal ASTRO updates guidance on pancreatic cancer ASTRO names new officers to its board ASTRO commends new prior authorization legislation (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 11, 2019 Category: Radiology Source Type: news

Mechanisms help pancreatic cancer cells avert starvation
(NYU Langone Health / NYU School of Medicine) A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 11, 2019 Category: Cancer & Oncology Source Type: news

Tropical flower offers potential new route for treating pancreatic cancer
(University of Bath) An international team of scientists led by the University of Bath have made drug-like molecules inspired by a chemical found in a tropical flower, that they hope could in the future help to treat deadly pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 11, 2019 Category: Cancer & Oncology Source Type: news

UCLA study shows inhibition of gene helps overcome resistance to immunotherapy
Cancer immunology drugs, which harness the body ’s immune system to better attack cancer cells, have significantly changed the face of cancer treatment. People with aggressive cancers are now living longer, healthier lives. Unfortunately, cancer immunology therapy only works in a subset of patients.Now, a new study from scientists at the UCLA Jonsson Comprehensive Cancer Center helps explain why some people with advanced cancer may not respond to one of the leading immunotherapies, PD-1 blockade, and how a new combination approach may help overcome resistance to the immunotherapy drug.TheUCLA study, published today i...
Source: UCLA Newsroom: Health Sciences - December 9, 2019 Category: Universities & Medical Training Source Type: news