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Parker Institute begins dosing in Phase Ib/II combination trial for pancreatic cancer
The Parker Institute for Cancer Immunotherapy and Cancer Research Institute in the US have started dosing patients in a Phase Ib/II clinical trial to investigate the combination of standard chemotherapy and immunotherapy for the treatment of pancreat … (Source: Drug Development Technology)
Source: Drug Development Technology - September 20, 2017 Category: Pharmaceuticals Source Type: news

Sean Parker's cancer-fighting institute aims 1st trial at tough target
Small Peninsula biotech company Apexigen and drug giant Bristol-Myers Squibb are teaming with the Parker Institute for Cancer Immunotherapy in an early-stage trial in metastatic pancreatic cancer patients. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - September 20, 2017 Category: Health Management Authors: Ron Leuty Source Type: news

Penn researchers identify new target, develop new drug for cancer therapies
(University of Pennsylvania School of Medicine) Opening up a new pathway to fight cancer, researchers at the University of Pennsylvania have found a way to target an enzyme that is crucial to tumor growth while also blocking the mechanism that has made past attempts to target that enzyme resistant to treatment. Researchers were able to use this finding to develop a drug that successfully inhibits tumor growth of melanoma as well as pancreatic and colorectal cancer in mice. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 20, 2017 Category: Cancer & Oncology Source Type: news

How bacteria hinder chemotherapy
(Weizmann Institute of Science) Scientists find bacteria in pancreatic tumors that metabolize a common drug. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 18, 2017 Category: Cancer & Oncology Source Type: news

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
Growing evidence suggests that microbes can influence the efficacy of cancer therapies. By studying colon cancer models, we found that bacteria can metabolize the chemotherapeutic drug gemcitabine (2',2'-difluorodeoxycytidine) into its inactive form, 2',2'-difluorodeoxyuridine. Metabolism was dependent on the expression of a long isoform of the bacterial enzyme cytidine deaminase (CDDL), seen primarily in Gammaproteobacteria. In a colon cancer mouse model, gemcitabine resistance was induced by intratumor Gammaproteobacteria, dependent on bacterial CDDL expression, and abrogated by cotreatment with the antibiotic ciprofloxa...
Source: ScienceNOW - September 14, 2017 Category: Science Authors: Geller, L. T., Barzily-Rokni, M., Danino, T., Jonas, O. H., Shental, N., Nejman, D., Gavert, N., Zwang, Y., Cooper, Z. A., Shee, K., Thaiss, C. A., Reuben, A., Livny, J., Avraham, R., Frederick, D. T., Ligorio, M., Chatman, K., Johnston, S. E., Mosher, C. Tags: Medicine, Diseases reports Source Type: news

Trial compares laparoscopic and open surgeries for pancreatic cancer
(Wiley) A randomized clinical trial has compared keyhole (laparoscopic) surgery and open surgery in pancreatic cancer patients undergoing pancreaticoduodenectomy, or the Whipple procedure. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

Researchers develop new strategy to target KRAS mutant cancer
(University of California - San Diego) In a new study, published this month in Cancer Discovery, University of California San Diego School of Medicine researchers report that approximately half of lung and pancreatic cancers that originate with a KRAS mutation become addicted to the gene as they progress. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 13, 2017 Category: International Medicine & Public Health Source Type: news

Tim Cook Gets Emotional Talking About Steve Jobs at Apple ’s Event: ‘I Love Hearing His Voice’
Apple’s anticipated keynote began with a touching tribute to the namesake of the location — Steve Jobs. The Tuesday keynote was the first event to take place in Steve Jobs Theater at Apple’s new campus, which Apple made sure to reference. The presentation began with a voiceover from Jobs himself. “I love hearing his voice,” Cook said as he launched the keynote address. “It was only fitting that Steve should open his theater.” Cook also said “not a day goes by that we don’t think of him” as he got emotional speaking of Jobs before beginning to announce all of Apple...
Source: TIME.com: Top Science and Health Stories - September 12, 2017 Category: Consumer Health News Authors: Lisa Marie Segarra Tags: Uncategorized Apple iPhone 2017 onetime Tim cook Source Type: news

A Pill Might Control Pancreatic Cancer, Even If It Doesn't Cure It
Rubraca Keeps Many Ovarian Cancers In Check. Could It Work As Maintenance Treatment In Pancreatic Cancer? (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 11, 2017 Category: Pharmaceuticals Authors: Elaine Schattner, Contributor Tags: NASDAQ:CLVS Source Type: news

Old Crohn's Theory Relevant Now? Gastro Endo News Report
(MedPage Today) -- Also, proton pump inhibitors and pancreatic cancer link (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 6, 2017 Category: Gastroenterology Source Type: news

Zinc transporter key to fighting pancreatic cancer and more
(Michigan State University) Patients suffering from Alzheimer's and Parkinson's disease harbor significantly higher levels of zinc and iron in their brains than healthy patients. Those with pancreatic cancer have an unusually high amount of a specific zinc transporter. So, controlling those levels could be an effective plan of attack against these diseases and others, said Jian Hu, Michigan State University biochemist. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 6, 2017 Category: International Medicine & Public Health Source Type: news

DNA and protein 'liquid biopsy' for early pancreatic cancer better than either alone
(Johns Hopkins Medicine) Johns Hopkins scientists say they have developed a blood test that spots tumor-specific DNA and protein biomarkers for early-stage pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 4, 2017 Category: Cancer & Oncology Source Type: news

Selfie app 'spots early signs of pancreatic cancer'
The software is designed to act as a low-cost early warning system for pancreatic tumours. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 31, 2017 Category: Consumer Health News Source Type: news

HealthWatch: Cancer-Detecting App; First-Time Dads Getting Older
BOSTON (CBS) — Pancreatic cancer usually has a poor prognosis, often because it’s caught too late, but could your smartphone one day give you an early warning? Researchers at the University of Washington are developing the BiliScreen app, which will allow people to screen themselves for pancreatic cancer and other diseases by snapping a selfie. The Biliscreen app in use. (WBZ-TV) One of the earliest signs of pancreatic cancer, and other conditions like hepatitis, is jaundice or yellowing of the eyes, which is caused by a build-up of a pigment called bilirubin in the blood. This BiliScreen app uses the smartphon...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 31, 2017 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Fathers HealthWatch Mallika Marshall Pancreatic Cancer Source Type: news

Pancreatic cancer symptoms: THIS everyday item could spot deadly condition early
PANCREATIC cancer has one of the worst outlooks because it often has no obvious symptoms. However, a new app may make diagnosis easier. (Source: Daily Express - Health)
Source: Daily Express - Health - August 31, 2017 Category: Consumer Health News Source Type: news

Smartphone'Selfies' May Help Diagnose Pancreatic Cancer Smartphone'Selfies' May Help Diagnose Pancreatic Cancer
A new smartphone app may improve screening for pancreatic cancer and other diseases, simply by taking'selfie. 'Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 30, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Digital health news briefs for 8/29/17
University of Washington app aims to detect pancreatic cancer early   (Source: mobihealthnews)
Source: mobihealthnews - August 29, 2017 Category: Information Technology Source Type: news

New selfie app can spot early signs of pancreatic cancer
Normally, by the time symptoms arise, patients have a nine percent chance of living five years. BiliScreen uses a camera to detect bile levels through the eyes before you can see it in a mirror. (Source: the Mail online | Health)
Source: the Mail online | Health - August 29, 2017 Category: Consumer Health News Source Type: news

New App Uses Smartphone Selfies to Screen for Pancreatic Cancer
Pancreatic cancer has one of the worst prognoses - with a five-year survival rate of 9 percent - in part because there are no telltale symptoms or non-invasive screening tools to catch a tumor before it spreads. Now, University of Washington researchers have developed an app that could allow people to easily screen for pancreatic cancer and other diseases - by snapping a smartphone selfie. (Source: eHealth News EU)
Source: eHealth News EU - August 29, 2017 Category: Information Technology Tags: Featured Research Research and Development Source Type: news

App uses smartphone selfies to screen for pancreatic cancer
Researchers at the University of Washington have developed an app that could allow people to screen for pancreatic cancer by using a smartphone selfie. (Source: Health News - UPI.com)
Source: Health News - UPI.com - August 28, 2017 Category: Consumer Health News Source Type: news

New app uses smartphone selfies to screen for pancreatic cancer
(University of Washington) A new app from University of Washington researchers could lead to earlier detection of pancreatic cancer simply by snapping a smartphone selfie. The disease kills 90 percent of patients within five years, in part because there are no telltale symptoms or non-invasive screening tools to catch a tumor before it spreads. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 28, 2017 Category: Cancer & Oncology Source Type: news

Data Trifecta-Cells, Media + FBS
Optimizing your Cell-Based AssaysResearchers need solid proof that the solutions the use will work in their assays. Given the time and effort it takes to culture human primary cells, it is important that the media and supplements used are optimized.We engineer our cell media and supplements to work with our primary and stem cells. Its potency is tested every day in our cell cultures.As further proof, we ask customers to share their data with us. We reward them by emailing a 50 USD Amazon gift card. I would like to recognize Emily Rodela from TGEN for sharing the Trifecta ofNeuromics'CAFS grown inMSC-Gro Media suppleme...
Source: Neuromics - August 21, 2017 Category: Neuroscience Tags: CAFs Cancer Associated Fibroblasts FBS Fetal Bovine Serum MSCgro Pancreatic CAF-Stellate Cells Source Type: news

'Junk food' may increase cancer risk in 'healthy weight' women
"Women who eat junk food such as burgers or pizza are increasing their risk of cancer even if they're not overweight, new research has warned," reports the Daily Mail. The story is based on research from the US looking at the diet of postmenopausal women in the 1990s and then tracking the development of a variety of cancers over about 15 years. "Junk food" is often defined as food that is rich in calories (energy dense food) but low in nutrients. Having a diet high in energy dense foods, such as biscuits, chocolate and pizza was found to increase the risk of cancer in these women, specifically in those ...
Source: NHS News Feed - August 18, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

Pancreatic cancer and diet link: How THIS energy dense food could affect you
CANCER, such as pancreatic, bowel and stomach cancer, has long been linked to be overweight or obese. (Source: Daily Express - Health)
Source: Daily Express - Health - August 18, 2017 Category: Consumer Health News Source Type: news

A metabolic treatment for pancreatic cancer?
Pancreatic cancer is now the third leading cause of cancer mortality. Its incidence is increasing in parallel with the population increase in obesity, and its five-year survival rate still hovers at just 8 to 9 percent. Research led by Nada Kalaany, PhD, at Boston Children's Hospital and the Broad Institute of MIT and Harvard, now suggests a novel approach to treating this deadly cancer: targeting an enzyme that tumors use to get rid of nitrogen. (Source: World Pharma News)
Source: World Pharma News - August 15, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

A metabolic treatment for pancreatic cancer?
(Boston Children's Hospital) Pancreatic cancer is now the third leading cause of cancer mortality. Its incidence is increasing in parallel with the population increase in obesity, and its five-year survival rate still hovers at just 8 to 9 percent. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 15, 2017 Category: Cancer & Oncology Source Type: news

Study pinpoints gene ’s new role in pancreatic cancer
A Yale-led study has identified a gene that is critical to pancreatic cancer cell growth, revealing a fresh target for new therapies. (Source: Yale Science and Health News)
Source: Yale Science and Health News - August 10, 2017 Category: Universities & Medical Training Source Type: news

Current Pancreatic Cancer Guidelines Miss Targetable Mutations
Germline mutations in pancreatic cancer susceptibility genes were commonly identified in a group of patients with pancreatic cancer who did not report a significant family history of cancer, according to the results of a single-center study. (Source: CancerNetwork)
Source: CancerNetwork - August 10, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Gastrointestinal Cancer News Pancreatic Cancer Source Type: news

Researchers identify prognostic indicators of survival following pancreatic tumor removal
(Mary Ann Liebert, Inc./Genetic Engineering News) A new study of patients who underwent curative surgical removal of a pancreatic ductal adenocarcinoma showed that two of the nine preoperative factors analyzed were strongly predictive of poor prognosis regardless of the tumor stage. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 10, 2017 Category: Cancer & Oncology Source Type: news

Cancer Associated Fibroblasts in Action
Publication ReferenceWe introduced ourCancer Associated Fibroblasts to researchers several years ago. The demand was strong from day one and continues to grow.We are pleased to announce the first reference in a Cancer Research Publication: Zenobia D'Costa, Keaton Jones, Abul Azad, Ruud van Stiphout, Su Y Lim, Ana L Gomes, Paul Kinchesh, Sean C Smart, W. Gillies McKenna, Francesca M Buffa, Owen J. Sansom, Ruth J. Muschel, Eric O'Neill and Emmanouil Fokas.Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer. Published OnlineFirst August 1, 2017 doi: 10.1158...
Source: Neuromics - August 9, 2017 Category: Neuroscience Tags: CAFs Cancer Associated Fibroblasts pancreas cancer Pancreatic CAF-Stellate Cells pancreatic cancer Pancreatic tumor cells Source Type: news

NICE recommends Celgene ’s pancreatic cancer treatment abraxane for NHS use
The UK National Institute for Health and Care Excellence (NICE) has recommended the routine use of Celgene ’s nab-paclitaxel as a life-extending treatment for patients with progressive pancreatic cancer that has progressed. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - August 7, 2017 Category: Pharmaceuticals Source Type: news

Pancreatic cancer: Patients to be given access to life-extending drugs on NHS
PATIENTS with incurable pancreatic cancer are to be given access to life-extending drugs on the NHS, under a new ruling announced today. (Source: Daily Express - Health)
Source: Daily Express - Health - August 3, 2017 Category: Consumer Health News Source Type: news

Mechanisms ID ’ d for Curcumin Resensitization of Cancer Cells
Compound helps turn off pathways linked to chemoresistance in pancreatic ductal adenocarcinoma (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - August 2, 2017 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Journal, Source Type: news

Does Radiotherapy in Unresectable Pancreatic Cancer Add Value?
This video reviews the conflicting data and perspectives regarding the use of radiotherapy in unresectable pancreatic cancer. (Source: CancerNetwork)
Source: CancerNetwork - August 2, 2017 Category: Cancer & Oncology Authors: John Ng, MD Tags: Pancreatic Cancer Videos Gastrointestinal Cancers Source Type: news

Medical News Today: Could a turmeric extract help to treat pancreatic cancer?
New research suggests that curcumin - a turmeric compound - may help to overcome resistance to chemotherapy in the treatment of pancreatic cancer. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 1, 2017 Category: Consumer Health News Tags: Pancreatic Cancer Source Type: news

Pancreatic cancer trial: Early surgery boosts success rates
New quicker approach to treatment cuts waiting times for surgery, and reduces cost to the NHS. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - August 1, 2017 Category: Consumer Health News Source Type: news

Pancreatic cancer breakthrough: THIS major change to treatment could save lives
PANCREATIC cancer - a disease which can be hard to spot because there are few symptoms - is one of the most deadly cancers in the UK. However, now experts have revealed particular way of treating patients could save the NHS thousands and boost survival. (Source: Daily Express - Health)
Source: Daily Express - Health - August 1, 2017 Category: Consumer Health News Source Type: news

Gene-regulatory factors shown to improve pancreatic cancer response to chemotherapy
(Tokyo Medical and Dental University) TMDU researchers revealed that, in pancreatic cancer, the microRNAs miR-509-5p and miR-1243 can promote E-cadherin expression and thereby reduce the likelihood of cells undergoing epithelial-mesenchymal transition, or indeed reverse this transition. This ability to stop cells from adopting a phenotype linked to high migration and invasiveness was also shown to synergistically increase the cancer cell-killing efficacy of gemcitabine, which is promising for developing more effective combinatorial treatments for pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 1, 2017 Category: Cancer & Oncology Source Type: news

UK NICE recommends nab-paclitaxel for pancreatic cancer
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - August 1, 2017 Category: Drugs & Pharmacology Source Type: news

Pancreatic cancer news: Fast-track surgery boots survival rates
FAST-TRACK surgery to treat pancreatic cancer increases its success rate by more than a fifth, saving the NHS £3,200 per patient, research has found. (Source: Daily Express - Health)
Source: Daily Express - Health - July 31, 2017 Category: Consumer Health News Source Type: news

Chemo Plus Hyperthermia Active in Advanced Pancreatic Cancer
Systemic and intraperitoneal chemotherapy + hyperthermia well tolerated and active (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 31, 2017 Category: Cancer & Oncology Tags: Gastroenterology, Internal Medicine, Oncology, Pharmacy, Radiology, Surgery, Journal, Source Type: news

To honor his uncle ’s memory, young doctor wants to offer hope to those with cancer
When Razmik Ghukasyan received his acceptance letter to the David Geffen School of Medicine at UCLA, he and his family were ecstatic. But their celebration was cut short days later when his uncle was diagnosed with advanced pancreatic cancer.During his first year of medical school, Ghukasyan frequently accompanied his uncle, Partev Kolanjian, to oncology appointments at another hospital. He was disturbed by the impersonal way his uncle ’s doctors treated him, which differed sharply from what Ghukasyan was learning at UCLA about the importance of a compassionate doctor-patient relationship.“In school, I was taug...
Source: UCLA Newsroom: Health Sciences - July 28, 2017 Category: Universities & Medical Training Source Type: news

Pancreatic Cancer Treatment
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 28, 2017 Category: General Medicine Source Type: news

AVENIO Tissue Dissection Instrument is an IVD labeled medical device.
AVENIO Tissue Dissection Instrument is designed to isolate relevant cells from formalin-fixed paraffin-embedded tissue slides. Unit is suitable for diagnostic test, sequencing and molecular methods. Product helps user to recognize mutations from 7 out of 32 pancreatic cancer tissues during sequencing samples. Instrument is compatible with variety of clinical workflow configurations.This story is related to the following:Instruments | (Source: Industrial Newsroom - Health, Medical and Dental Supplies)
Source: Industrial Newsroom - Health, Medical and Dental Supplies - July 27, 2017 Category: Medical Devices Source Type: news

How a sponge could cure pancreatic cancer - would YOU recognise symptoms of the disease?
PANCREATIC cancer, one of the UK ’s deadliest forms of cancer, could one day be treated, or even cured - after experts found a small green sponge from the sea floor in Alaska could kill the tumour. (Source: Daily Express - Health)
Source: Daily Express - Health - July 27, 2017 Category: Consumer Health News Source Type: news

Pancreatic cancer CURE: Simple organism on sea-bed can KILL tumour cells
PANCREATIC cancer, one of the UK ’s deadliest forms of cancer, could one day be treated, or even cured - after experts found a small green sponge from the sea floor in Alaska could kill the tumour. (Source: Daily Express - Health)
Source: Daily Express - Health - July 27, 2017 Category: Consumer Health News Source Type: news

Pancreatic cancer CURE - deep-water green sponge could KILL deadly disease
PANCREATIC cancer, one of the UK ’s deadliest forms of cancer, could one day be treated, or even cured - after experts found a small green sponge from the sea floor in Alaska could kill the tumour. (Source: Daily Express - Health)
Source: Daily Express - Health - July 27, 2017 Category: Consumer Health News Source Type: news

Could a green sponge hold cancer-fighting secrets?
A small green sponge discovered in dark, icy waters of the Pacific off Alaska could be the first effective weapon against pancreatic cancer, researchers said. It also killed ovarian cancer cells. (Source: the Mail online | Health)
Source: the Mail online | Health - July 27, 2017 Category: Consumer Health News Source Type: news

New SU2C-Lustgarten Foundation team aims to apply CAR T-cell therapy to pancreatic cancer
(American Association for Cancer Research) Stand Up To Cancer is supporting a new translational research team to explore how a type of immunotherapy that has been very successful in blood cancers can be applied to pancreatic cancer, the American Association for Cancer Research, SU2C's Scientific Partner, announced today. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 27, 2017 Category: Cancer & Oncology Source Type: news

Long-sought mechanism of metastasis is discovered in pancreatic cancer
(Cold Spring Harbor Laboratory) An important discovery at CSHL establishes a cause of metastasis in pancreatic cancer. Using organoids grown from patient tissues and transplanted in mouse models of the illness, the team pinpoints an epigenetic re-programming of gene enhancers that returns cancerous cells to a more primitive developmental state, dating back to the formation of the pancreas, in which cells multiply rapidly and are not yet anchored in tissue. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 27, 2017 Category: Cancer & Oncology Source Type: news