Lycopene found to inhibit pathway involved in Helicobacter pylori-induced gastric cancer
In this study, researchers at Yonsei University in South Korea evaluated the effects of lycopene on hyperproliferation induced by Helicobacter pylori infection. They reported their findings in an article published in the journal Nutrition Research. H. pylori is known to colonize the human stomach and is linked to an increased risk of gastric diseases,... (Source: NaturalNews.com)
Source: NaturalNews.com - April 6, 2021 Category: Consumer Health News Source Type: news

Mayo Clinic Q & amp;A podcast: Esophageal cancer is one of the deadliest cancers
Esophageal cancer occurs in the esophagus -- a long, hollow tube that runs from the throat to the stomach -- and can occur anywhere along the esophagus. Men are more likely to develop esophageal cancer than women. While treatable, esophageal cancer is rarely curable. "It's an uncommon cancer," says Dr. Shanda Blackmon, a Mayo Clinic general thoracic surgeon. [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 5, 2021 Category: Databases & Libraries Source Type: news

Stomach bloating: Is it gas or a sign of bowel cancer? It depends on the other symptoms
STOMACH bloating can feel tight and uncomfortable, but it might be a warning sign of advanced bowel cancer. How can you be sure it's only a little bit of gas, or if the swelling is due to fluid build-up? (Source: Daily Express - Health)
Source: Daily Express - Health - March 27, 2021 Category: Consumer Health News Source Type: news

Aging cells in abdominal fluid cause increased peritoneal dissemination of gastric cancer
(Kumamoto University) Through an analysis of cell fractions from malignant ascites, cellular senescence of cancer-associated fibroblasts (CAFs) has been found to be important in the progression of gastric cancer peritoneal dissemination foci. This understanding should enable the development of new treatments for peritoneal cancer dissemination by targeting cancer cells at dissemination sites and CAFs in patients with peritoneal dissemination. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 23, 2021 Category: Biology Source Type: news

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profi...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Variations in a gene and a protein aggravate the prognosis of one gastric tumor
(Universidad Complutense de Madrid) More than a million people worldwide were diagnosed with stomach cancer in 2018, the fifth most prevalent cancer. The most common gastric tumor is gastric adenocarcinoma, originating in the gastric mucosa. A research team led by the University Complutense of Madrid in Spain has identified 2 biomarkers that help predict the risk of developing the disease, as well as a poorer prognosis: polymorphisms-variations-of the transforming growth factor B1 (TGFB1) gene and the TGFB1 protein. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 18, 2021 Category: Cancer & Oncology Source Type: news

Andecaliximab Disappoints in Advanced Gastric Cancer Andecaliximab Disappoints in Advanced Gastric Cancer
Objective response rates were 50.5% in the ADX arm and 41.1% in the placebo arm, but this did not translate to improved survival.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 10, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Gallbladder cancer symptoms: Dark urine could be a sign of the deadly disease
THE GALLBLADDER is a small organ that aids the stomach in digestion. When a cancerous tumour forms in that area, the symptoms may seem innocuous. However, put together they could signify a deadly disease. (Source: Daily Express - Health)
Source: Daily Express - Health - March 6, 2021 Category: Consumer Health News Source Type: news

Longtime Bay Area cancer biotech snagged by Amgen in $1.9B deal
The Peninsula biotech shed more than half its jobs in recent years but stayed focused on its gastric cancer drug bemarituzumab, which is ready for Phase III clinical trials and could be used to attack a number of other types of cancer. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 5, 2021 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

Amgen buys longtime cancer biotech in $1.9 billion deal
The Peninsula biotech shed more than half its jobs in recent years but stayed focused on its gastric cancer drug bemarituzumab, which is ready for Phase III clinical trials and could be used to attack a number of other types of cancer. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - March 4, 2021 Category: American Health Authors: Ron Leuty Source Type: news

Stomach bloating: ‘Sudden’ bloating could signal a deadly disease - what is it?
STOMACH bloating is often a natural response to eating gassy foods but it can signal something serious is up. If you experience sudden bloating, it could signal cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - March 1, 2021 Category: Consumer Health News Source Type: news

FDA D.I.S.C.O. Burst Edition: Enhertu (fam-trastuzumab deruxtecan-nxki ) and combination of Opdivo (nivolumab) and Cabometyx (cabozantinib)
Enhertu (fam-trastuzumab deruxtecan-nxki) for locally advanced or metastatic HER2-positive gastric or gastroesophageal adenocarcinoma and received a prior trastuzumab-based regimen. Combination of Opdivo (nivolumab) + Cabometyx (cabozantinib) as first-line treatment for advanced renal cell carcinoma (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 25, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Prostate cancer: Stomach pain, constipation or blood in stools are signs not to ignore
PROSTATE cancer is the most common cancer in men in the UK, with around 40,000 men diagnosed with prostate cancer every year in England alone. Symptoms can take years to surface and when the cancer has advanced there are three warning signs you should not ignore. (Source: Daily Express - Health)
Source: Daily Express - Health - February 12, 2021 Category: Consumer Health News Source Type: news

Bowel cancer: Tenesmus - a sensation when using the toilet - is a warning sign
BOWEL cancer symptoms include weight loss, stomach pain, and feeling very tired for no obvious reason. But you could also be at risk of the disease if you notice small changes to your daily toilet routine, in particular a certain sensation. (Source: Daily Express - Health)
Source: Daily Express - Health - February 10, 2021 Category: Consumer Health News Source Type: news

An Atypical Presentation of Multiple Primary Malignancies An Atypical Presentation of Multiple Primary Malignancies
Gastric carcinoma is the neoplasm most commonly associated with second primary neoplasms. This case underscores the need to consider multiple primary malignancy in patients with gastric cancer.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 10, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

A novel approach to determine how carcinogenic bacteria find their targets
(Texas A&M University) The gram-negative bacteria Helicobacter pylori (H. pylori) colonize the stomachs of the majority of the world's population. Although most people may never experience major complications due to the pathogen, H. pylori infections increase the risk of certain types of gastric cancer, as well as other illnesses such as peptic ulcers and gastritis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 10, 2021 Category: Cancer & Oncology Source Type: news

FDA D.I.S.C.O. Burst Edition: FDA Approvals of Xalkori for patients 1-21 years with ALK-positive ALCL and Enhertu for adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal adenocarcinoma
(Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 9, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Elderly esophageal cancer patients often receive suboptimal therapy due to perceived risks
(American College of Surgeons) Elderly patients (70 years and over) with locally advanced esophageal (E) and esophagogastric junction (EGJ) cancer (located in the stomach and esophagus) should be considered for optimal therapy that has the potential to cure. This therapy regimen includes initial chemoradiotherapy (NACR) and surgical resection, an operation that removes the cancerous part of the organ. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 9, 2021 Category: Cancer & Oncology Source Type: news

Bowel cancer symptoms: Stomach pain could be indicative of the disease
BOWEL cancer begins in either the colon or rectum, both of which are part of the large bowel. As abnormal cells divide and grow in an uncontrollable manner, signs of the disease start to manifest. (Source: Daily Express - Health)
Source: Daily Express - Health - February 6, 2021 Category: Consumer Health News Source Type: news

Stomach bloating: When is bloating a sign of bowel cancer? What you need to know
BLOATING in the stomach is usually attributed to eating too many gassy foods but it can be a sign of advanced bowel. There are a number of telltale signs that can signal your stomach bloating is a sign of bowel cancer. (Source: Daily Express - Health)
Source: Daily Express - Health - February 2, 2021 Category: Consumer Health News Source Type: news

Can Teenagers Get Stomach Cancer
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 26, 2021 Category: General Medicine Source Type: news

Bemarituzumab FIGHTs Gastric/GEJ Cancers, Improving Survival Bemarituzumab FIGHTs Gastric/GEJ Cancers, Improving Survival
Adding bemarituzumab to chemotherapy as first-line treatment for advanced gastric and gastroesophageal junction (GEJ) cancers improved survival over chemotherapy alone in the phase 2 FIGHT trial.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 19, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

Better Survival With S-1/Docetaxel in Stage III Gastric Cancer Better Survival With S-1/Docetaxel in Stage III Gastric Cancer
Postoperative adjuvant S-1/docetaxel after D2 gastrectomy significantly improved survival in comparison with S-1 alone for patients with stage III gastric cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 18, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Gut Microbiome Predicts Nivolumab Efficacy in Gastric Cancer? Gut Microbiome Predicts Nivolumab Efficacy in Gastric Cancer?
Preliminary data suggest that the diversity of the gut microbiome could potentially predict nivolumab response for patients with gastric cancer.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 18, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Enhertu Approved in the U.S. for the Treatment of Patients With Previously Treated HER2 Positive Advanced Gastric Cancer
TOKYO& MUNICH& BASKING RIDGE, N.J.--(BUSINESS WIRE) January 15, 2021 -- Daiichi Sankyo Company, Ltd.  (hereafter, Daiichi Sankyo) and AstraZeneca’s Enhertu (fam-trastuzumab deruxtecan-nxki) has been approved in the U.S. for the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - January 15, 2021 Category: Drugs & Pharmacology Source Type: news

FDA approves fam-trastuzumab deruxtecan-nxki for HER2-positive gastric adenocarcinomas
On January 15, 2021, the Food and Drug Administration approved fam-trastuzumab deruxtecan-nxki (Enhertu, Daiichi Sankyo) for adult patients with locally advanced or metastatic HER2-positive gastric or gastroesophageal (GEJ) adenocarcinoma who have received a prior trastuzumab-based regimen. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - January 15, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Dolly Parton health: Country star’s suspected cancer in the stomach – symptoms to spot
DOLLY PARTON health: Dolly is no stranger to rumours and allegations with many related to her health. The star allegedly suffered from stomach cancer a few years back. What are the symptoms of the deadly disease? (Source: Daily Express - Health)
Source: Daily Express - Health - January 15, 2021 Category: Consumer Health News Source Type: news

AI predicts metastasis in gastric cancer patients
An artificial intelligence (AI) algorithm can predict the presence of occult...Read more on AuntMinnie.comRelated Reading: AI helps predict lung cancer screening eligibility AI tool beats traditional breast cancer risk assessments AI body analysis finds lung cancer survival risk factors AI improves lung cancer detection on x-rays AI may predict lymph node metastasis in gastric cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 8, 2021 Category: Radiology Source Type: news

Deep learning helps predicting occult peritoneal metastasis in stomach cancer
(Chinese Academy of Sciences Headquarters) A new study led by the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences shows that deep learning can help predicting the occult peritoneal metastasis in stomach cancer. It provides a novel and noninvasive approach for stomach cancer patients and may inform individualized surgical management of stomach cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 7, 2021 Category: Cancer & Oncology Source Type: news

Single-cell analysis of metastatic gastric cancer finds diverse tumor cell populations associated with patient outcomes
(University of Texas M. D. Anderson Cancer Center) Researchers from The University of Texas MD Anderson Cancer Center who profiled more than 45,000 individual cells from patients with peritoneal carcinomatosis (PC), a specific form of metastatic gastric cancer, defined the extensive cellular heterogeneity and identified two distinct subtypes correlated with patient survival. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 4, 2021 Category: International Medicine & Public Health Source Type: news

Endoscopy cost effective for gastric cancer screening after H. pylori eradication
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2021 Category: Drugs & Pharmacology Source Type: news

Sask. woman who got stomach removed to thwart cancer describes life with 'ticking time bomb'
Genetic testing revealed that Summer Heide has a gene mutation that increases her chances of developing a deadly stomach cancer. That discovery has forced Heide to make agonizing decisions that affect her life and the lives of her children. (Source: CBC | Health)
Source: CBC | Health - December 20, 2020 Category: Consumer Health News Tags: News/Canada/Saskatchewan Source Type: news

New therapeutic target pinpointed for stomach cancer
(Walter and Eliza Hall Institute) WEHI researchers have identified a key molecular regulator, TNF, which is involved in the progression and spread of stomach cancer, suggesting a potential new approach to treat this devastating disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 16, 2020 Category: Cancer & Oncology Source Type: news

Bowel cancer: Experiencing trapped wind or having a fullness in the tummy are danger signs
BOWEL cancer: The stomach and digestion are a complicated system. Feeling extra gassy, bloated and having abdominal pain are experiences many are all too familiar with. However, having a persistent feeling of trapped wind or a fullness in the tummy no matter how much or how little you have eaten are symptoms of bowel cancer and should not be ignored. (Source: Daily Express - Health)
Source: Daily Express - Health - December 8, 2020 Category: Consumer Health News Source Type: news

Stomach cancer symptoms: Ongoing dyspepsia could be a warning sign of the disease
STOMACH cancer can begin in any part of the muscular bag, including its wall. However, the disease predominantly starts in the gland cells in the inner stomach lining. Ongoing dyspepsia could be a warning sign of the condition. (Source: Daily Express - Health)
Source: Daily Express - Health - December 6, 2020 Category: Consumer Health News Source Type: news

How a longtime Peninsula biotech company's stomach cancer drug moved closer to the finish line
Results this month from the company's mid-stage clinical trial sent its stock soaring and helped it raise $174 million. But it took nine years, layoffs, CEO changes and serendipity to get there. (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - November 25, 2020 Category: American Health Authors: Ron Leuty Source Type: news

Stomach cancer: Indigestion and acid reflux symptoms could be warning signs
STOMACH cancer: With the Christmas season upon us, so is the start of overindulgence. It's normal for a person to feel slight discomfort after a particular meal or drink, however large levels of discomfort which persists and causes acid reflux could spell something far more dangerous. (Source: Daily Express - Health)
Source: Daily Express - Health - November 24, 2020 Category: Consumer Health News Source Type: news

UC Santa Cruz teams up, pools data to fight stomach cancer
(University of California - Santa Cruz) The UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer to release a web portal designed to help researchers identify individuals at risk of heritable stomach cancers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 24, 2020 Category: International Medicine & Public Health Source Type: news

What are Potential Problems Associated with Helicobacter pylori?
Discussion Helicobacter pylori (H. pylori) is a microaerophilis, spiral bacterium that is a prevalent human pathogen. How this infection affects individuals is different in adults and children. Overall seroprevalence rate in children world-wide was estimated to be ~33%, but this seroprevalence rate is decreasing in the developed world for both adults and children. It is acquired in childhood and can persist through colonization throughout life if untreated. Fortunately, it often is asymptomatic and generally does not cause serious disease in children. Some serotyping data shows that within families children acquire it more...
Source: PediatricEducation.org - November 23, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Mesothelioma Surgery with Organ Removal Extends Survival
Removing major organs to achieve a more complete cancer resection did not increase severe complications or hinder survival benefits of aggressive surgery for patients with peritoneal mesothelioma, according to a recent report. The increased complexity of organ resection surgery will not adversely affect long-term outcomes, according to the multicenter study published in Annals of Surgical Oncology. By comparison, an incomplete cytoreduction that can spare the organs is associated with increased mortality and shorter overall survival. The study, which involved 174 patients across 12 specialty centers within the U.S., accent...
Source: Asbestos and Mesothelioma News - November 17, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

Zimbabwe: Stomach Cancer Notorious Disease
[Zimbabwe Standard] Many people are dying from cancers unnoticed in this world. The rural populace is one that is at a disadvantage in making early diagnosis because of lack of medical investigations like scans. Those who seek remedy from traditional healers will be told all sorts of stories yet the cancer will be spreading. Last week, we lost one of our greatest actors, Lazarus Boora, aka Gringo, to the notorious cancer of the stomach. Rest in peace, the Mayor of Rukweza. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - November 16, 2020 Category: African Health Source Type: news

Sussex research points to new effective breast cancer treatment
(Diamond Light Source) An international five-year study led by scientists at the University of Sussex has provided strong evidence for an effective new target for breast cancer treatment. The study, The structure-function relationship of oncogenic LMTK3 being published in Science Advances, involved researchers from seven institutions across three countries including the UKs Diamond Light Source. It suggests LMTK3 inhibitors could be effectively used for treatment of breast cancer, and potentially other types of cancer such as lung, stomach, thyroid and bladder cancer patients (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 13, 2020 Category: Cancer & Oncology Source Type: news

Immunotherapy may work better in stomach cancer when combined with chemo, given earlier
(Columbia University Irving Medical Center) Immunotherapy, often ineffective against stomach cancer, was more effective when combined with chemotherapy and given earlier, finds a new study in mice. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 5, 2020 Category: International Medicine & Public Health Source Type: news

Oesophageal cancer symptoms: Prolonged indigestion could be a sign of the deadly disease
OESOPHAGEAL cancer occurs when abnormal cells multiply uncontrollably in the food pipe . This is the passageway between the mouth to the stomach. Prolonged indigestion could be a sign of the deadly disease. (Source: Daily Express - Health)
Source: Daily Express - Health - November 4, 2020 Category: Consumer Health News Source Type: news

PFUA Intake and Head and Neck and Gastric Cancer Incidence PFUA Intake and Head and Neck and Gastric Cancer Incidence
Can dietary intake of dietary long-chain n-3 polyunsaturated fatty acid protect against head and neck or upper GI cancers?American Journal of Epidemiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 3, 2020 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

Advances in the Treatment of Gastric Cancer Advances in the Treatment of Gastric Cancer
This article provides an updated review on the surgical and adjuvant management of cancers of the stomach and esophagogastric junction.Current Opinion in Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 30, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Stomach bloating: The main sign to spot warning your bloating may be cancer
STOMACH bloating is a condition most don't need to worry about, and symptoms often subside after some time. However, sometimes bloating could be an early sign of something far more sinister. How can you tell if your bloating may be a warning sign of cancer? (Source: Daily Express - Health)
Source: Daily Express - Health - October 27, 2020 Category: Consumer Health News Source Type: news