Probiotic Proves Its Might for Staph Decolonization
(MedPage Today) -- A Bacillus subtilis probiotic demonstrated the ability to wipe out most Staphylococcus aureus colonization without altering the gut microbiome, a placebo-controlled phase II study conducted in Thailand showed. Of 115 healthy... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 19, 2023 Category: Infectious Diseases Source Type: news

Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in Staphylococcus aureus | Science Signaling
Acid-induced antibiotic tolerance in S.  aureus depends on serine-threonine phosphorylation. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - January 3, 2023 Category: Science Source Type: news

Most Global Bacterial Deaths in 2019 Linked to Five Pathogens Most Global Bacterial Deaths in 2019 Linked to Five Pathogens
Worldwide, researchers estimate Staphylococcus aureus was linked to more than 1 million deaths, while four more pathogens were associated with more than 500,000 deaths each.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - November 22, 2022 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news

Cost-minimisation analysis of oritavancin for the treatment of acute bacterial skin and skin structure infections from a United Kingdom perspective.
Conclusion: Oritavancin, used to support ED, is associated with lower costs compared with dalbavancin and reduced treatment duration relative to all comparators. Its use would support an ED approach in MRSA ABSSSI management. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news

Emergence of High Antimicrobial Resistance among Critically Ill Patients with Hospital-Acquired Infections in a Tertiary Care Hospital.
Conclusions: The current study describes the high antibiotic resistance patterns in various hospital units that need extra legislation to prevent healthcare providers from misprescription and overuse of antibiotics. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news

Mobile phones as a vector for Healthcare-Associated Infection: A systematic review.
Conclusions: The use of mobile phones by healthcare workers without proper disinfection may imply a risk for nosocomial infection. A direct relationship however, remains unproven. Healthcare workers are recommended to include proper handling of mobile phones in their ' classic ' hand hygiene routine as proposed by the World Health Organisation. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news

Determination of Virulence Factors and Resistance Profile of Methicillin-Resistant Staphylococcus aureus Strains among Different Types of spa, agr, and SCCmec
The objective of this study was to determine virulence factors and resistance profiles of MRSA strains among spa, agr, and SCCmec types. In total, 55 MRSA isolates were collected from clinical specimens. The MRSA isolates were characterized by antimicrobial susceptibility testing, virulence genes, agr typing, spa typing, and SCCmec typing. According to our findings, all MRSA strains were resistant to cefoxitin; 88% and 86.7% of which were resistant to erythromycin and clindamycin, respectively. Type II agr was predominant with 54.54% frequency. Among 27 different spa types, type t030 was most frequently (25.45%). Most MRSA...
Source: Current Awareness Service for Health (CASH) - November 15, 2022 Category: Consumer Health News Source Type: news

High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting.
In this study we aimed to investigate proportions of patients that received discordant empirical antimicrobial therapy and its association to mortality. Methods: A retrospective cohort study model was undertaken to outline BSI in an intensive care, single centre, and low antimicrobial resistance prevalence setting. We used descriptive statistics to delineate proportions of patients that received discordant empirical antimicrobial therapy, and a correlation model and a logistic regression model to calculate the association with mortality and predictors of receiving discordant therapy, respectively. Results: From 2014 to 2...
Source: Current Awareness Service for Health (CASH) - November 2, 2022 Category: Consumer Health News Source Type: news

A Once-Rejected Antibiotic Equals Standard for Complicated Staph Infections
(MedPage Today) -- WASHINGTON -- Investigational ceftobiprole was just as effective as daptomycin for bacterial bloodstream infections caused by Staphylococcus aureus bacteremia, the phase III ERADICATE trial demonstrated. In the randomized... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 25, 2022 Category: Infectious Diseases Source Type: news

Innovative Patented Appliances Allow Oral Care for NIV Patients without Mask Removal
SALT LAKE CITY, Oct. 11, 2022 /PRNewswire/ -- ReddyPort, a NIV-focused medical technology company, announced today that US Patent No 11,324,910 has been issued by the US Patent Office covering Positive Pressure Ventilation Appliance Modules and Related Systems and Methods. ReddyPort Ò products promote NIV success by empowering clinicians with efficient access to provide standardized oral care without removing the mask or loss of therapeutic pressures. Clinicians recognize delivering effective and compliant oral care to the NIV patient can be particularly challenging. Studies s how respiratory pathogens such as Staphylococ...
Source: Dental Technology Blog - October 15, 2022 Category: Dentistry Source Type: news

Assessment of the effect of hand dryers used in shopping malls on hand hygiene
This study was conducted to investigate the effect of hand dryers used in the restrooms located on the food court floor s in shopping malls in Turkey on hand hygiene. Hands were washed for at least 20 seconds by following hygienic hand washing procedures of the World Health Organization. Swab samples were taken from the wet hands after hand washing, then from the dry hands, which were dried under the hand dryers and from the air blowing part of the hand dryers. Samples were cultured on agar plates that were directly exposed to the air-blowing part of the hand dryers. It was found that total coliform bacteria were 0.000 col...
Source: Current Awareness Service for Health (CASH) - October 14, 2022 Category: Consumer Health News Source Type: news

High levels of discordant antimicrobial therapy in hospital-acquired bloodstream infections is associated with increased mortality in an intensive care, low antimicrobial resistance setting.
In this study we aimed to investigate proportions of patients that received discordant empirical antimicrobial therapy and its association to mortality. Methods: A retrospective cohort study model was undertaken to outline BSI in an intensive care, single centre, and low antimicrobial resistance prevalence setting. We used descriptive statistics to delineate proportions of patients that received discordant empirical antimicrobial therapy, and a correlation model and a logistic regression model to calculate the association with mortality and predictors of receiving discordant therapy, respectively. Results: From 2014 to 2...
Source: Current Awareness Service for Health (CASH) - October 7, 2022 Category: Consumer Health News Source Type: news

Africa: Answering the Challenges Posed by Antimicrobial Resistance
[allAfrica] Staphylococcus aureus is the source of a skin infection that can turn deadly if drug resistant. Estimates regarding the most common resistant variation, methicillin-resistant Staphylococcus aureus (MRSA), exceed 100,000 deaths globally in 2019. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 30, 2022 Category: African Health Source Type: news

Africa: Answering the Challenges Posed By Antimicrobial Resistance on the Continent
[IPS] Staphylococcus aureus is the source of a skin infection that can turn deadly if drug resistant. Estimates regarding the most common resistant variation, methicillin-resistant Staphylococcus aureus (MRSA), exceed 100,000 deaths globally in 2019. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - September 22, 2022 Category: African Health Source Type: news

Answering the Challenges Posed by Antimicrobial Resistance
We are failing to take antimicrobial resistance seriously, perhaps because it is not glamorous and relatable. Credit: Bigstock.By External SourceSep 21 2022 (IPS) Staphylococcus aureus is the source of a skin infection that can turn deadly if drug resistant. Estimates regarding the most common resistant variation, methicillin-resistant Staphylococcus aureus (MRSA), exceed 100,000 deaths globally in 2019. But up until recently, we did not have a solid grasp on how much of a problem MRSA—or any other antimicrobial resistant pathogen—was in Africa. It turns out, after testing 187,000 samples from 14 countries for antibiot...
Source: IPS Inter Press Service - Health - September 21, 2022 Category: International Medicine & Public Health Authors: External Source Tags: Africa Headlines Health Source Type: news