Hope for a vaccination against Staphylococcus areus infections?
(German Center for Infection Research) Staphylococcus aureus (S. aureus) ranks among the globally most important causes of infections in humans and is considered a dreaded hospital pathogen. Active and passive immunisation against multi-resistant strains is seen as a potentially valuable alternative to antibiotic therapy. However, all vaccine candidates so far have been clinically unsuccessful. With an epitope-based immunisation, scientists at Cologne University Hospital and the German Center for Infection Research (DZIF) have now described a new vaccination strategy against S. aureus in the Nature Partner JournalNPJ VACCI...
Source: EurekAlert! - Infectious and Emerging Diseases - January 20, 2021 Category: Infectious Diseases Source Type: news
Diclofenac mitigates virulence of multidrug-resistant Staphylococcus aureus. Archives of microbiology 202(10): 2751-2760.
In conclusion, diclofenac can be used in combination with antibiotics as anti-virulence agent against MDR-MRSA which will enhance the ability of immune system to eradicate infection. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 15, 2021 Category: Consumer Health News Source Type: news
Characterizing Common Wound Microbes in Epidermolysis Bullosa Characterizing Common Wound Microbes in Epidermolysis Bullosa
Wound cultures from patients with epidermolysis bullosa were most frequently positive for Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus pyogenes; antibiotic resistance was common.Medscape Medical News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - January 7, 2021 Category: Dermatology Tags: Dermatology News Source Type: news
High Glucose May Make MRSA More Virulent in Diabetes Patients High Glucose May Make MRSA More Virulent in Diabetes Patients
High glucose levels in the tissue and blood of people with diabetes may help make drug-resistant Staphylococcus aureus infections more aggressive, new mouse research suggests.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 25, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
Understanding lung infections in patients with cystic fibrosis
(University of Warwick) For young people with cystic fibrosis, lung infection with Staphylococcus aureus, MRSA, is common and is treated with antibiotics in the hope that this will prevent a decline in lung function. However there has recently been debate over the role S. aureus plays in CF lung disease. Researchers from the University of Warwick have used a new model of CF lungs which could be used to make better decisions about future use of antibiotics. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 19, 2020 Category: Infectious Diseases Source Type: news
The effectiveness of education of methicillin-resistant Staphylococcus aureus (MRSA) infection prevention and control (IPC) with directive discourse to improve handwashing compliance
The incidence rate of microbial exposure remains high among nurses. Paramedics play a vital role in transmitting the nosocomial infection in the hospital. This research aims to analyze the education effectivity of MRSA IPC with directive discourse to improve handwashing compliance among nurses. This is quasi-experimental research using a pretest –posttest non-control design and has obtained an ethical approval certificate issued by the hospital ethical committee. A research subject is a group of 25 nurses. The data test uses the Wilcoxon test to determine the measuring result of handwashing compliance before and after th...
Source: Current Awareness Service for Health (CASH) - November 18, 2020 Category: Consumer Health News Source Type: news
Scientists discover secret to superbug's virulence in diabetic infections
(University of Pittsburgh) The bodies of people with uncontrolled diabetes appear to be the perfect environment for a common type of superbug to thrive unchecked and do its worst damage, according to new research reported today in Science Advances. Staphylococcus aureus -- a bacteria that is often resistant to antibiotics -- thrives in glucose-rich diabetic conditions, which trigger it to activate some of its most virulent features. A lack of insulin prevents the immune system from responding to the infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 13, 2020 Category: Infectious Diseases Source Type: news
Dr MARTIN SCURR answers your health questionsÂ
DR MARTIN SCURR: A boil - proper name, furuncle - is an infection of the skin which begins in a hair follicle. It is usually due to a bacterium called Staphylococcus aureus. (Source: the Mail online | Health)
Source: the Mail online | Health - October 20, 2020 Category: Consumer Health News Source Type: news
Bacterial toxin with healing effect
(Friedrich-Schiller-Universitaet Jena) A bacterial toxin promoting tissue healing has been discovered by an international research team led by scientists from University of Jena (Germany). The compoundα-Hemolysine found in Staphylococcus aureus does not just damage cells, but also stimulates tissue regeneration. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 13, 2020 Category: Biology Source Type: news
Mortality related to drug-resistant organisms in surgical sepsis-3: an 8-year time trend study using sequential organ failure assessment scores
The difference in sequential organ failure assessment (SOFA) scores from the baseline to sepsis is a known predictor of sepsis-3 outcome, but the prognostic value of drug-resistant organisms for mortality is unexplained. We employed sepsis stewardship and herein report an observational study. Study subjects were patients admitted to the Departments of Surgery/Chest Surgery from 2011 through 2018 with a diagnosis of sepsis and a SOFA score of 2 or more. Our sepsis stewardship methods included antimicrobial and diagnostic stewardship and infection control. We determined the primary endpoint as in-hospital death and the secon...
Source: Current Awareness Service for Health (CASH) - October 9, 2020 Category: Consumer Health News Source Type: news
Reductions in Methicillin-resistant Staphylococcus aureus, Clostridium difficile Infection and Intensive Care Unit-Acquired Bloodstream Infection Across the United Kingdom Following Implementation of a National Infection Control Campaign
Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections declined across the UK National Health Service in the decade that followed implementation of an infection control campaign. The national impact on intensive care unit (ICU)-acquired infections has not been documented. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 23, 2020 Category: Consumer Health News Source Type: news
Customizable synthetic antibiotic outmaneuvers resistant bacteria
(University of California - San Francisco) Antibiotic resistance is one of the world's most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria such as Staphylococcus aureus and Enterococcus faecium, which can cause virtually untreatable hospital-acquired infections. Perilously few new classes of antibiotics are being developed to fight infections that have become resistant to traditional treatments, and bringing any new drugs to market could take decades. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 23, 2020 Category: Infectious Diseases Source Type: news
Gary Nabors, Ph.D. Joins Integrated BioTherapeutics Inc. as Executive...
IBT is pioneering development of the first multivalent toxoid-based vaccine against Staphylococcus aureus as well as immunotherapies for several viral diseases.(PRWeb September 14, 2020)Read the full story at https://www.prweb.com/releases/gary_nabors_ph_d_joins_integrated_biotherapeutics_inc_as_executive_vice_president_and_chief_development_officer/prweb17389568.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - September 14, 2020 Category: Pharmaceuticals Source Type: news
How to spot patients most likely to die from blood infections
(University of California - San Diego) Unprecedented analysis of proteins and metabolites in patient serum provides new biomarkers associated with a patient's risk of dying from Staphylococcus aureus bacteremia. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 3, 2020 Category: Infectious Diseases Source Type: news
Vaccine that harnesses antifungal immunity protects mice from staph infection
(PLOS) Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus (S. aureus) proteins protects mice against S. aureus infection, according to a study published August 20 2020 in the open-access journal PLOS Pathogens by David Underhill of Cedars-Sinai Medical Center, and colleague. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 20, 2020 Category: Infectious Diseases Source Type: news
