Influence of pharmacists and infection control teams or antimicrobial stewardship teams on the safety and efficacy of vancomycin: A Japanese administrative claims database study
Conclusion: Pharmacologic management for individual patients, rather than assignment systems at facilities, is effective to reduce AKI and 30-day mortality with VCM administration. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 20, 2022 Category: Consumer Health News Source Type: news
Vancomycin area under the curve versus trough only guided dosing and the risk of acute kidney injury: Systematic review and meta-analysis
Vancomycin is commonly used to treat methicillin-resistant Staphylococcus aureus infections and is known to cause nephrotoxicity. Previous Vancomycin Consensus Guidelines recommended targeting trough concentrations but the 2020 Guidelines suggest monitoring vancomycin area under the curve (AUC) given the reduced risk of acute kidney injury (AKI) at similar levels of efficacy. This meta-analysis compares vancomycin-induced AKI incidence using AUC-guided dosing strategies versus trough-based monitoring. Literature was queried from Medline (Ovid), Web of Science, and Google Scholar from database inception through November 5, ...
Source: Current Awareness Service for Health (CASH) - September 20, 2022 Category: Consumer Health News Source Type: news
Meticillin-susceptible Staphylococcus aureus transmission among healthcare workers, patients and the environment in a large acute hospital under non-outbreak conditions investigated using whole-genome sequencing
Conclusions: WGS detected numerous potential hospital MSSA TEs involving HCWs, patients and environmental contamination under non-outbreak conditions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 20, 2022 Category: Consumer Health News Source Type: news
Breaking down antibiotic resistance in methicillin-resistant Staphylococcus aureus : Combining antimicrobial photodynamic and antibiotic treatments.
The widespread use of antibiotics drives the evolution of antimicrobial-resistant bacteria (ARB), threatening patients and healthcare professionals. Therefore, the development of novel strategies to combat resistance is recognized as a global healthcare priority. The two methods to combat ARB are development of new antibiotics or reduction in existing resistances. Development of novel antibiotics is a laborious and slow-progressing task that is no longer a safe reserve against looming risks. In this research, we suggest a method for reducing resistance to extend the efficacious lifetime of current antibiotics. Antimicrobia...
Source: Current Awareness Service for Health (CASH) - September 20, 2022 Category: Consumer Health News Source Type: news
Innovative Patented Appliances Allow Oral Care for NIV Patients without Mask Removal
SALT LAKE CITY, Oct. 11, 2022 /PRNewswire/ -- ReddyPort, a NIV-focused medical technology company, announced today that US Patent No 11,324,910 has been issued by the US Patent Office covering Positive Pressure Ventilation Appliance Modules and Related Systems and Methods. ReddyPort Ò products promote NIV success by empowering clinicians with efficient access to provide standardized oral care without removing the mask or loss of therapeutic pressures. Clinicians recognize delivering effective and compliant oral care to the NIV patient can be particularly challenging. Studies s how respiratory pathogens such as Staphylococ...
Source: Dental Technology Blog - September 17, 2022 Category: Dentistry Source Type: news
Do patients need advice and information to prevent infections - results of a single centre structured survey
Conclusion: Our data suggest a lack of information on infection prevention and control among patients and underline the importance of patient empowerment. The willingness of patients to pay personally for antiseptic wash should be assessed further. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 8, 2022 Category: Consumer Health News Source Type: news
Clinical implementation of routine whole-genome sequencing for hospital infection control of multi-drug resistant pathogens
Conclusions: Implementation of routine WGS for MDR pathogens in clinical laboratories is feasible and can enable targeted infection prevention and control interventions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 8, 2022 Category: Consumer Health News Source Type: news
Mayo Clinic in Arizona achieves second Magnet designation in recognition of nursing excellence
PHOENIX — Mayo Clinic in Arizona has received its second Magnet designation from the American Nurses Credentialing Center, with nine exemplars noted. Exemplars are areas where Mayo Clinic in Arizona significantly exceeded Magnet standards for clinical excellence. Mayo Clinic outperformed the benchmarks in all nursing units for: Post-lumbar puncture headaches.Hospital-acquired methicillin-resistant Staphylococcus aureus infections.Patient falls in the ambulatory setting.Four different measures of inpatient patient satisfaction. Other exemplars included: 89% of Mayo Clinic nurses with a bacc...
Source: Mayo Clinic Arizona News - August 25, 2022 Category: Hospital Management Source Type: news
Clinical utility of negative methicillin-resistant Staphylococcus aureus (MRSA) nasal surveillance swabs in skin and skin structure infections
Conclusion: Patients with a negative MRSA nasal swab received approximately 1 day less of vancomycin, which represented a decrease in drug administered. The negative predictive value for SSSIs is promising, showing potential for the role of MRSA nasal swabs in de-escalating therapy. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 19, 2022 Category: Consumer Health News Source Type: news
Microbial bioburden of inpatient and outpatient areas beyond patient hospital rooms.
Conclusions: Surfaces in hospitals outside patient rooms and in outpatient facilities are frequently contaminated with healthcare-associated pathogens. Improvements in cleaning and disinfection practices are needed to reduce contamination. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 19, 2022 Category: Consumer Health News Source Type: news
Impact of the WHO Integrated Stewardship Policy on the Control of Methicillin-Resistant Staphyloccus aureus and Third-Generation Cephalosporin-Resistant Escherichia coli: Using a Mathematical Modeling Approach
Methicillin-resistant Staphylococcus aureus (MRSA) and third-generation cephalosporin-resistant Escherichia coli (3GCREc) are community and hospital-associated pathogens causing serious infections among populations by infiltrating into hospitals and surrounding environment. These main multi-drug resistant or antimicrobial resistance (AMR) bacterial pathogens are threats to human health if not properly tackled and controlled. Tackling antimicrobial resistance (AMR) is one of the issues for the World Health Organization (WHO) to design a comprehensive set of interventions which also helps to achieve the end results of the de...
Source: Current Awareness Service for Health (CASH) - August 19, 2022 Category: Consumer Health News Source Type: news
Radiology imaging equipment and accessories as possible fomites of nosocomial pathogens
Conclusions: The research concluded that the recommended cleaning agents did not effectively reduce the number of microorganisms making the selected equipment and accessories fomites for nosocomial pathogens. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 16, 2022 Category: Consumer Health News Source Type: news
Armata Pharmaceuticals Announces Clearance of IND for Prosthetic Joint Infections
Second indication for AP-SA02 which targets Staphylococcus aureus including MRSA
Potential to significantly improve PJI patient outcomes
Expands Armata's pursuit of phage therapy as a solution for difficult-to-treat infections
MARINA DEL REY, Cali... Biopharmaceuticals, FDA Armata Pharmaceuticals, bacteriophage, Staphylococcus aureus (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 1, 2022 Category: Pharmaceuticals Source Type: news
Mobile phones as a vector for Healthcare-Associated Infection: A systematic review
Conclusions: The use of mobile phones by healthcare workers without proper disinfection may imply a risk for nosocomial infection. A direct relationship however, remains unproven. Healthcare workers are recommended to include proper handling of mobile phones in their ' classic ' hand hygiene routine as proposed by the World Health Organisation. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 22, 2022 Category: Consumer Health News Source Type: news
Structure-oriented design strategy to construct NIR AIEgens to selectively combat gram (+) multidrug-resistant bacteria in vivo.
Multidrug-resistant (MDR) gram-positive bacteria are an inevitable source of infection for hospitalized patients and one of the reasons for the increased proportion of severe diseases. Therefore, constructing smart agents for specific and effective combating infections in vivo caused by MDR gram-positive strains is very urgent. Herein, we reported a structure-oriented design strategy (SODS) to reasonably construct an organic photo-antimicrobial near-infrared (NIR) AIEgen BDPTV equipped with a phenylboronic acid moiety, which could be bound to the thick peptidoglycan layer of MDR gram-positive bacteria, resulting in a tight...
Source: Current Awareness Service for Health (CASH) - July 20, 2022 Category: Consumer Health News Source Type: news
