Parenteral Antimicrobial Tx at Home Burdens Children's Caregivers
WEDNESDAY, April 17, 2019 -- The overall burden of outpatient parenteral antimicrobial therapy (OPAT) is substantially higher than that of oral therapy for caregivers of children on prolonged antimicrobial therapy after hospital discharge, according... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 17, 2019 Category: Pharmaceuticals Source Type: news

Tracking global trends in the effectiveness of antibiotic therapy using the Drug Resistance Index
(Center for Disease Dynamics, Economics& Policy) Using resistance data from CDDEP's ResistanceMap and antibiotic use data obtained from IQVIA's MIDAS database, researchers calculated the DRI rates for 41 countries. Overall, the DRI rates varied widely across countries and ranged from a low of 8.1 in Sweden to a high of 71.6 in India. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 17, 2019 Category: International Medicine & Public Health Source Type: news

Non-antibiotic therapies for sepsis: an update
Sepsis, defined as infection plus some degree of organ dysfunction, is still associated with high mortality and morbidity rates. Management focuses on three key areas: infection control, hemodynamic stabilization and organ support, and modulation of the sepsis response. Areas covered: This review will not cover infection control. Hemodynamic stabilization essentially involves use of adequate fluid resuscitation and vasopressors. Fluid and vasopressor choices and targets are discussed, and the need to adapt these to the individual patient is stressed. No drugs are currently available that modulate the sepsis response, with ...
Source: Current Awareness Service for Health (CASH) - March 28, 2019 Category: Consumer Health News Source Type: news

Incision & Drainage of Perianal Sepsis in the Immunocompromised: A Need for Heightened Postoperative Awareness
Incision and drainage of perianal sepsis has appreciable success in the immunocompetent population, but outcomes after incision and drainage in the immunosuppressed population are unknown. Immunosuppression is an independent risk factor for major morbidity, return to the operating room, and mortality. With post-operative sepsis the most common complication, inpatient admission and extended duration antibiotic therapy is warranted in immunosuppressed patients. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 22, 2019 Category: Consumer Health News Source Type: news

Minocycline for Acne Changes Skin Microbiota
(MedPage Today) -- Findings in pilot study may explain adverse effects of antibiotic therapy in acne (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - February 16, 2019 Category: Dermatology Source Type: news

Patients With Bone Infections May Benefit As Much From Oral Antibiotics As IVs, OVIVA Study Finds
For patients with bone infections, there is no significant difference in response between oral antibiotics and prolonged IV antibiotic therapy per new OVIVA study. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - February 11, 2019 Category: Pharmaceuticals Authors: Judy Stone, Contributor Source Type: news

IllumiCare inks deal with Minnesota company
IllumiCare has secured a partnership with a Minneapolis-based clinical surveillance company. The Birmingham-based firm will work with VigiLanz to increase visibility within provider’s and pharmacist’s normal workflows around antimicrobial therapy monitoring. Financial details were not released to the BBJ. Illumicare will apply its Smart Ribbon technology with VigiLanz’s Antimicr obial Stewardship Solution. This is intended to increase engagement at hospitals and save pharmacists time tracking… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - February 7, 2019 Category: Biotechnology Authors: Tyler Patchen Source Type: news

IllumiCare inks deal with Minnesota company
IllumiCare has secured a partnership with a Minneapolis-based clinical surveillance company. The Birmingham-based firm will work with VigiLanz to increase visibility within provider’s and pharmacist’s normal workflows around antimicrobial therapy monitoring. Financial details were not released to the BBJ. Illumicare will apply its Smart Ribbon technology with VigiLanz’s Antimicr obial Stewardship Solution. This is intended to increase engagement at hospitals and save pharmacists time tracking… (Source: bizjournals.com Health Care:Physician Practices headlines)
Source: bizjournals.com Health Care:Physician Practices headlines - February 7, 2019 Category: American Health Authors: Tyler Patchen Source Type: news

Cellulitis or Cellulitis Mimic? How to Tell the Difference Cellulitis or Cellulitis Mimic? How to Tell the Difference
Real cases seen by an ID specialist in recent weeks illustrate conditions that can mimic cellulitis and lead to inappropriate antibiotic therapies.Medscape Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 25, 2019 Category: Consumer Health News Tags: Infectious Diseases Case Challenge Source Type: news

Management of Neonates Born at 35 0/7 Weeks' Gestation With Suspected or Proven Early-Onset Bacterial Sepsis
The authors of this journal article say that the incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last 2 decades, primarily because of the implementation of evidence-based intrapartum antimicrobial therapy. However, EOS remains a serious and potentially fatal illness. Laboratory tests alone are neither sensitive nor specific enough to guide EOS management decisions. Maternal and infant clinical characteristics can help identify newborn infants who are at risk and guide the administration of empirical antibiotic therapy. The incidence of EOS, the prevalence and implications of established r...
Source: Current Awareness Service for Health (CASH) - January 17, 2019 Category: Consumer Health News Source Type: news

Effectiveness and safety of procalcitonin evaluation for reducing mortality in adults with sepsis, severe sepsis or septic shock
This Cochrane Review was Substantively amended in January 2019. However, there was no change to the conclusion, that Up-to-date evidence of very low to moderate quality, with insufficient sample power per outcome, does not clearly support the use of procalcitonin-guided antimicrobial therapy to minimize mortality, mechanical ventilation, clinical severity, reinfection or duration of antimicrobial therapy of patients with septic conditions. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - January 11, 2019 Category: Consumer Health News Source Type: news

Cellulitis Risk Score May Help Guide IV Antibiotic Therapy in Children Cellulitis Risk Score May Help Guide IV Antibiotic Therapy in Children
Pediatricians from Australia have developed and validated a simple risk-assessment score to help guide decisions regarding antibiotic therapy for cellulitis in children.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 5, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock
This review concludes that there is no adequate, direct evidence as to whether de-escalation of antimicrobial agents is effective and safe for adults with sepsis, severe sepsis or septic shock. The authors say this uncertainty warrants further research via RCTs and the authors are awaiting the results of an ongoing RCT testing the de-escalation of empirical antimicrobial therapy for severe sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 28, 2018 Category: Consumer Health News Source Type: news

Atlas of Shared Learning: Outpatient parental antibiotic therapy at Whittington Health NHS Trust
This case study outlines how the Lead Outpatient Parenteral Antibiotic Therapy (OPAT) Nurse at Whittington Health NHS Trust led on the development and implementation of new pathways and services, to reduce unwarranted variation by ensuring patients could be discharged home safely and still receive their antibiotic therapy as recommended. This has led to better outcomes, experiences and use of resources. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 5, 2018 Category: Consumer Health News Source Type: news

With these nanoparticles, a simple urine test could diagnose bacterial pneumonia
(Massachusetts Institute of Technology) MIT researchers have now developed a nanoparticle-based technology that could be used distinguish between bacterial and viral forms of pneumonia. The technology could also be used to monitor whether antibiotic therapy has successfully treated the infection. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 29, 2018 Category: Infectious Diseases Source Type: news

Zimmer Biomet Recalls 1,300 Bone Growth and Spinal Fusion Stimulators
A recall that Zimmer Biomet initiated in February has just been identified by FDA as a Class I recall, marking it the most serious type of medical device recall. The company is recalling 1,360 implantable bone growth and spinal fusion stimulators that are used to help heal bone following spinal fusion surgery or to help heal broken long bones, such as a leg or arm bone. These devices are placed during surgery and are designed to send a low-level electrical signal to encourage the body's natural healing process. Several sessions at MD&M West 2019 will focus on regulatory and quality issues that i...
Source: MDDI - November 27, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news

Zimmer Biomet recalls bone stimulators on contamination risk
Zimmer Biomet (NYSE:ZBH) recalled nearly 1,400 bone stimulators on the risk that they could be contaminated with bacteria or chemicals, the FDA said yesterday. The Class I recall, denoting the risk of serious injury or death, covers 1,360 implantable bone growth and spinal fusion stimulators made and distributed between February 2015 and March 2018, including Zimmer Biomet’s Osteogen, SpF Plus-Mini and SpF-XL stimulators, the federal safety watchdog said. The devices are designed to stimulate healing after spinal fusion procedures or long-bone breaks. The voluntary recall was launched Feb. 19 “due to ...
Source: Mass Device - November 27, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Featured Orthopedics Recalls Regulatory/Compliance Spinal Zimmer Biomet Source Type: news

Diagnostics Are Helping Counter Antimicrobial Resistance, But More Work Is Needed
Antimicrobial resistance (AMR) threats to patient health are becoming more widely recognized and diagnostics manufacturers are making significant progress in combatting the overuse of antibiotics. There is still a lot of work to be done, however. A recent health scare for Rick Bright, Ph.D., director of the Biomedical Advanced Research and Development Authority (BARDA), HHS, the very agency working to combat emerging infectious diseases (EID) and other threats, highlights the lingering risks.  During the 10th Public Meeting of the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB...
Source: MDDI - November 21, 2018 Category: Medical Devices Authors: Daphne Allen Tags: IVD Source Type: news

Cytomorphometric Neutrophil and Monocyte Markers May Strengthen the Diagnosis of Sepsis
The authors of this research article state that the diagnosis of sepsis is challenging in the absence of a gold standard test. Recent studies have explored the role of neutrophil and monocyte volume, conductivity, and scatter (VCS), derived from automated hematology analyzers, in diagnosing sepsis. The authors assessed the diagnostic accuracy of VCS parameters in critically ill patients with sepsis. They say that in critically ill patients with suspected sepsis, VCS parameters may help strengthen the diagnostic probability of sepsis. Future studies may explore the role of serial monitoring of VCS to track response to antim...
Source: Current Awareness Service for Health (CASH) - November 16, 2018 Category: Consumer Health News Source Type: news

ID specialist input improves outcomes for outpatient parenteral antimicrobial therapy
(Infectious Diseases Society of America) An infectious diseases specialist should review all orders for outpatient IV antimicrobial therapy and adjust as needed, suggest new guidelines released by the Infectious Diseases Society of America (IDSA). (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 13, 2018 Category: Infectious Diseases Source Type: news

Low Recurrence With Shortened IV Abx Course in GBS Bacteremia
THURSDAY, Oct. 11, 2018 -- For infants with uncomplicated, late-onset group B Streptococcus (GBS) bacteremia, a shortened intravenous (IV) course of antibiotic therapy is sometimes prescribed and is associated with low rates of disease recurrence... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 11, 2018 Category: Pharmaceuticals Source Type: news

Emergency department sepsis screening tool decreases time to antibiotics in patients with sepsis
The purpose of this study was to evaluate the impact of a sepsis screening tool implemented in an academic medical center ED on compliance with the 3-hour sepsis bundle. Although implementation of an ED sepsis screening tool did not increase 3-hour bundle compliance, it did increase the proportion of patients receiving timely antimicrobial therapy and demonstrated a trend towards decreased mortality. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 29, 2018 Category: Consumer Health News Source Type: news

Extended- vs Narrow-Spectrum Antibiotics in Appendicitis Extended- vs Narrow-Spectrum Antibiotics in Appendicitis
What is the best choice of antibiotic therapy for uncomplicated appendicitis in children? Dr Lowenfels comments on a study published in Annals of Surgery.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 19, 2018 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

GI Dynamics wins FDA nod for pivotal US EndoBarrier trial
GI Dynamics (ASX:GID) said today it won FDA investigational device exemption approval to launch a pivotal trial of its EndoBarrier device designed for treating patients with type 2 diabetes and obesity, pending Institutional Review Board approval. The EndoBarrier device is a plastic gut sleeve designed to prevent the absorption of nutrients from food as it exits the stomach and enters the intestinal tract to treat type 2 diabetes and obesity, the Lexington, Mass.-based company said. The approval is a boon for the company, which has faced a number of hurdles with its device over the past few years, inclu...
Source: Mass Device - August 13, 2018 Category: Medical Devices Authors: Fink Densford Tags: Clinical Trials Diabetes Food & Drug Administration (FDA) Regulatory/Compliance Weight loss GI Dynamics Source Type: news

Outpatient parenteral antibiotic therapy system saves costs
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - August 1, 2018 Category: Drugs & Pharmacology Source Type: news

Rapid genetic testing can prevent hearing loss in newborns treated for sepsis
(European Society of Human Genetics) More than a million neonatal deaths worldwide each year are estimated to be due to sepsis. Many patients receive antibiotic therapy during their hospital stay, but babies with a specific genetic change can suffer irreversible hearing loss as a result. Now, a rapid test for distinguishing those infants who will have this adverse reaction to gentamicin has been developed. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 14, 2018 Category: Infectious Diseases Source Type: news

Bone apetit: How bacteria eat bone to sustain invasive infection
(American Society for Microbiology) Researchers from Vanderbilt University Medical Center have determined the metabolic pathway that Staphylococcus aureus use to survive in bones. Invasive S. aureus infections frequently occur in the bone and are notoriously resistant to antimicrobial therapy. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology, held from June 7-11 in Atlanta, Ga. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 8, 2018 Category: Biology Source Type: news

Most Premature Infants Receive Early Antibiotics
TUESDAY, May 29, 2018 -- Most premature infants receive empirical antibiotic therapy, according to a study published online May 25 in JAMA Network Open. Dustin D. Flannery, D.O., from the Children's Hospital of Philadelphia, and colleagues examined... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 30, 2018 Category: Pharmaceuticals Source Type: news

Each hour of delay in detecting abnormal lactates in patients with sepsis increases the odds of in-hospital death
(Elsevier) Because of a known association between elevated lactate levels and increased mortality, sepsis guidelines mandate that lactate levels should be tested soon after the onset of sepsis. A new study in the journal CHEST ® found that a significant proportion of patients with suspected sepsis do not have their lactates measured within the recommended timeframe. These patients experienced delayed antibiotic therapy and IV fluid administration, as well as increased risk of in-hospital death. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 24, 2018 Category: International Medicine & Public Health Source Type: news

Evaluating the appropriateness of antimicrobial treatment in hospitalized patients: a comparison of three methods
This research article concluded that rates of appropriateness of antimicrobial therapy varied between evaluation methods, with low to moderate agreement between the different methods. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 9, 2018 Category: Consumer Health News Source Type: news

Antibiotic therapy for preventing infections in people with acute stroke
This review article concludes preventive antibiotics had no effect on functional outcome or mortality, but significantly reduced the risk of'overall'infections. This reduction was driven mainly by prevention of urinary tract infection; no effect for pneumonia was found. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 2, 2018 Category: Consumer Health News Source Type: news

New infection prevention tool improve transparency and standardization of practice
(European Society of Clinical Microbiology and Infectious Diseases) Researchers developed a new color-coded visual tool called Infection Risk Scan, or IRIS, which is set to make it easier for healthcare workers to measure in which areas a hospital complies with guidelines and where it needs to implement measures to improve infection control and the use antimicrobial therapies, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - April 20, 2018 Category: Biology Source Type: news

Duration of Antibiotics Often Exceeds Guidelines for Sinusitis
THURSDAY, March 29, 2018 -- The durations of most courses of antibiotic therapy for adult outpatients with sinusitis exceed guideline recommendations, according to a research letter published online March 26 in JAMA Internal Medicine. Laura M. King,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 29, 2018 Category: Pharmaceuticals Source Type: news

Sepsis caused by bloodstream infection in patients in the intensive care unit: the impact of inactive empiric antimicrobial therapy on outcome
This research article concludes that mortality from sepsis is influenced by multiple factors. The study was unable to demonstrate that inactive AMT had an effect on mortality in sepsis. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - March 28, 2018 Category: Consumer Health News Source Type: news

STI positivity rate and treatment uptake among female and male sexual assault victims attending the Amsterdam STI clinic between 2005 and 2016 - van Rooijen MS, Schim van der Loeff MF, van Kempen L, de Vries HJC.
BACKGROUND: Victims could become infected with sexually transmitted infections (STI) during a sexual assault. Several guidelines recommend presumptive antimicrobial therapy for sexual assault victims (SAV). We assessed the STI positivity rate and treatment... (Source: SafetyLit)
Source: SafetyLit - February 26, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Most Infection Specialists Fail to Advise Short-duration Antibiotic Therapy Most Infection Specialists Fail to Advise Short-duration Antibiotic Therapy
Most infection specialists who give at least weekly advice to colleagues regarding antibiotic prescriptions fail to specify the shortest possible duration of therapy, according to an international cross-sectional survey.Reuters Health Information (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - February 2, 2018 Category: Infectious Diseases Tags: Dermatology News Source Type: news

Adjunctive Rifampin Not Beneficial for Staph aureus Bacteremia Adjunctive Rifampin Not Beneficial for Staph aureus Bacteremia
Adjunctive rifampin, also called rifampicin, provides no significant benefit over standard antibiotic therapy in patients with Staphylococcus aureus bacteremia, according to results from the ARREST trial.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - December 29, 2017 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Evaluating Appropriateness of Antimicrobial Treatment in Hospitalized Patients: A Comparison of Three Methods
This Research Article found that among 106 patients included, rates of appropriateness of antimicrobial therapy ranged from 20-75%, depending on method of evaluation. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 22, 2017 Category: Consumer Health News Source Type: news

The Risk Factors in Early Failure of Dental Implants: a Retrospective Study
Conclusion: It seems that prophylactic antibiotic therapy, implant surface, bone density and placement in fresh extraction socket may contribute to dental implant failure. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 8, 2017 Category: Dentistry Source Type: news

Bacteria eradication reduces gastric cancer risk by 22 percent in over-60s, new research shows
(Spink Health) The research analyzed the risk of gastric cancer development in a large group of individuals who had received antibiotic therapy to treat H. pylori infection. Of those who had been treated over the age of 60, 0.8 percent developed gastric cancer, in comparison to 1.1 percent of patients in an age-matched general population sample. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 30, 2017 Category: Cancer & Oncology Source Type: news

Endogenous infection marker guides antibiotic therapy
(University of Basel) The endogenous infection marker procalcitonin can help to guide the use of antibiotics when treating infections. The course of antibiotic therapy is shortened, and its side effects and mortality rate also decrease, as researchers from the University of Basel and other colleagues report in the journal The Lancet Infectious Diseases. They conducted a meta-analysis of over 6,700 international data sets from patients with respiratory infections. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - October 16, 2017 Category: Infectious Diseases Source Type: news

Procalcitonin-Guided Antibiotic Therapy Tied to Improved Survival in Acute Respiratory Infection (FREE)
By Amy Orciari Herman Edited by Susan Sadoughi, MD, and Andr é Sofair, MD, MPH For patients with acute respiratory tract infection, using procalcitonin levels to guide treatment decisions can reduce antibiotic use and improve survival, finds a meta-analysis in the Lancet Infectious Diseases. High procalcitonin levels can … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 16, 2017 Category: Primary Care Source Type: news

Antibiotic identified that reduces infection risk in young leukemia patients
(St. Jude Children's Research Hospital) St. Jude Children's Research Hospital investigators report preventive antibiotic therapy, particularly with levofloxacin, reduced the odds of infections in at-risk pediatric leukemia patients early in cancer treatment. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 14, 2017 Category: Infectious Diseases Source Type: news

Lactococcus garviae Prosthetic Mitral Valve Endocarditis: a Case Report and Literature Review
We report a new case of L. garviae prosthetic mitral valve endocarditis that was managed with antibiotic therapy alone. (Source: Clinical Microbiology Newsletter)
Source: Clinical Microbiology Newsletter - August 10, 2017 Category: Microbiology Authors: Ewout Landeloos, Guy Van Camp, Hans De Beenhouwer Tags: Case Report Source Type: news

Steering a Transition in Antibiotic Prescribing: Just-in-Time, Not Just-in-Case
Antibiotics are the most common medication prescribed in post-acute and long-term care facilities, and suspected urinary tract infection is the most frequent indication for initiation of antibiotic therapy. However, there has been a growing realization that much of this treatment is unnecessary and potentially harmful. (Source: Caring for the Ages)
Source: Caring for the Ages - July 28, 2017 Category: Health Management Authors: Peter P. Patterson Tags: Guest Editorial Source Type: news

Procalcitonin-guided decision making for duration of antibiotic therapy in neonates with suspected early-onset sepsis: a multicentre, randomised controlled trial (NeoPIns)
This research article concludes that procalcitonin-guided decision making was superior to standard care in reducing duration of antibiotic therapy in neonates with suspected early-onset sepsis (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - July 21, 2017 Category: Consumer Health News Source Type: news

Antibiotic treatment to prevent post-extraction complications: a monocentric, randomized clinical trial. Preliminary outcomes.
CONCLUSIONS:Post-extractive complications observed in each group have been mild and fast to resolve. The antibiotic administration showed a decrease in pain suffered by patients but a higher incidence of gastro-intestinal side effects, such as abdominal distension and diarrhea, which seemed to be relieved by the concomitant use of the probiotic. (Source: Dental Technology Blog)
Source: Dental Technology Blog - June 12, 2017 Category: Dentistry Source Type: news

Antibiotics vs Surgery: Equally Effective for Appendicitis? Antibiotics vs Surgery: Equally Effective for Appendicitis?
Dr Lowenfels comments on a study examining whether antibiotic therapy is an effective replacement for standard surgical appendectomy, published in Annals of Surgery.Medscape General Surgery (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 2, 2017 Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news

New approach to antibiotic therapy is a dead end for pathogens
(Molecular Biology and Evolution (Oxford University Press)) In the case of the pathogen Pseudomonas aeruginosa, the evolution of resistance to certain antibiotics leads to an increased susceptibility to other drugs. This concept of so-called 'collateral sensitivity' opens up new perspectives in the fight against multi-resistant pathogens. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 1, 2017 Category: Infectious Diseases Source Type: news

Long-term antibiotic prophylaxis reduces mortality in people with advanced liver disease
(European Association for the Study of the Liver) A multicenter, randomized, controlled study presented today found that long-term oral antibiotic therapy with norfloxacin improved the prognosis of people with life-threatening advanced liver disease. The study, presented at The International Liver Congress ™ 2017 in Amsterdam, The Netherlands, showed that norfloxacin administration for six months was associated with a reduced risk of death and infection at six months in patients with Child-Pugh class C cirrhosis, a very severe and advanced stage of liver disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 20, 2017 Category: Infectious Diseases Source Type: news