Risankizumab Has Early and Lasting Benefits in Crohn's Disease Risankizumab Has Early and Lasting Benefits in Crohn's Disease
Risankizumab takes effect within the first few weeks and has enduring effects in Crohn's disease, phase 3 trials suggest.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 28, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Upadacitinib Shows Potential for Ulcerative Colitis Upadacitinib Shows Potential for Ulcerative Colitis
Good efficacy and safety data provide hope for upadacitinib as an alternative JAK inhibitor for ulcerative colitis.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 26, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately t...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Ustekinumab Maintenance Therapy in Ulcerative Colitis Ustekinumab Maintenance Therapy in Ulcerative Colitis
This study to assess the real-world effectiveness and safety of ustekinumab in patients with refractory ulcerative colitis confirms long-term effectiveness with a good safety profile.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 20, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Crohn’s disease: The food increasing your risk of the condition by 80 percent - BMJ study
INFLAMMATORY bowel disease is an umbrella term used to describe two separate conditions caused by a malfunctioning immune system. Both ulcerative and Crohn's disease are characterised by chronic inflammation and irritation in the lining of the digestive tract. (Source: Daily Express - Health)
Source: Daily Express - Health - October 19, 2021 Category: Consumer Health News Source Type: news

Childhood maltreatment and psychiatric comorbidity in immune-mediated inflammatory disorders - Wan A, Bernstein CN, Graff LA, Patten SB, Sareen J, Fisk JD, Bolton JM, Hitchon C, Marriott JJ, Marrie RA.
OBJECTIVE: To determine whether childhood maltreatment is associated with immune-mediated inflammatory disorders (IMID; multiple sclerosis [MS], inflammatory bowel disease [IBD] and rheumatoid arthritis [RA]). We further aimed to determine the relationship... (Source: SafetyLit)
Source: SafetyLit - October 18, 2021 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Crohn's Disease: No Decline in Stomas Despite Anti-TNF Therapy Crohn's Disease: No Decline in Stomas Despite Anti-TNF Therapy
Despite the increasing use of anti –TNF medications and a low rate of proctectomy, a recent analysis finds no decline in stoma incidence among patients.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 13, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Crohn's Disease: No Decline in Stomas With Anti-TNF Therapy Crohn's Disease: No Decline in Stomas With Anti-TNF Therapy
Despite the increasing use of anti –TNF medications and a low rate of proctectomy, a recent analysis finds no decline in stoma incidence among patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2021 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

What Is Crohn's Disease?
Title: What Is Crohn's Disease?Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 10/13/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - October 13, 2021 Category: Nutrition Source Type: news

Rectal Compliance Lower Than Normal in Ulcerative Colitis, but Recovery Is Possible Rectal Compliance Lower Than Normal in Ulcerative Colitis, but Recovery Is Possible
Rectal compliance is lower in patients with ulcerative colitis than in those without, but recovery is possible, researchers suggest.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 8, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Janssen Submits Application Seeking U.S. FDA Approval of STELARA ® (ustekinumab) for the Treatment of Pediatric Patients With Juvenile Psoriatic Arthritis
HORSHAM, PENNSYLVANIA, October 8, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking expanded approval of STELARA® (ustekinumab) to treat pediatric patients ages 5 years and older with juvenile psoriatic arthritis (jPsA).The filing is supported by extrapolation of data from nine studies across both adult trials in active PsA and adult and pediatric studies in moderate to severe plaque psoriasis, totaling 3,997 patients evaluated across these closely associa...
Source: Johnson and Johnson - October 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

How to Maintain Your Social Life When You Have IBD
About two years ago, as Samantha Plevney was dealing with a major Crohn’s disease flare-up, she decided to tell her gastroenterologist how it was affecting her emotional health. “I told him that I’m alive but I’m not living,” she recalls. “Not being able to see my friends because of the uncertainty of my health situation was making me feel worse. I think people with IBD, and their doctors, tend to focus on physical symptoms, and for good reason. But the mental-health effect that comes from social support is huge.” Inflammatory bowel disease (IBD) encompasses two conditions—Cr...
Source: TIME: Health - October 5, 2021 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Source Type: news

New Analysis Presented by Janssen at United European Gastroenterology Week (UEGW) Demonstrates Long-Term Safety Profile for STELARA ® (ustekinumab) in Older Patients Across Approved Indications
SPRING HOUSE, PENNSYLVANIA, October 4, 2021 – Today, the Janssen Pharmaceutical Companies of Johnson & Johnson announced a new analysis of STELARA® (ustekinumab) pooled safety data from 13 clinical studies across approved indications, showing rates of key safety events among adults 60 years and older treated with STELARA for up to five yearsa were similar to rates observed with placebo during the control phase of these trials.1,b Approved indications included adults with moderately to severely active Crohn’s disease (CD), moderately to severely active ulcerative colitis (UC), moderate to severe plaque p...
Source: Johnson and Johnson - October 4, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

How Do You Get Crohns
How Do You Get Crohn's Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 1, 2021 Category: General Medicine Source Type: news

Crohn’s disease: Stomach condition causes eye disorders – four symptoms to spot
CROHN'S disease can affect people of all ages, including children with roughly 115,000 people in the UK suffering from it. Early symptoms can strangely be found in the eyes with any of these four signs warning you may be heading for it. (Source: Daily Express - Health)
Source: Daily Express - Health - September 30, 2021 Category: Consumer Health News Source Type: news

Crohn's disease: Five symptoms that could prove life-threatening if not treated early
CROHN'S disease is a chronic condition where parts of the digestive system become inflamed. Though various studies have looked into the causes of Crohn's disease, the actual cause is unknown. However, scientists do know that it is one type of a condition known as inflammatory bowel disease . If Crohn's disease is not diagnosed, fatal complications can result. In rare cases, these complications can be fatal. (Source: Daily Express - Health)
Source: Daily Express - Health - September 29, 2021 Category: Consumer Health News Source Type: news

Benefit of 5ASA Use After Anti-TNF or Immunomodulator in IBD Benefit of 5ASA Use After Anti-TNF or Immunomodulator in IBD
5ASA is still used as first-line therapy in the treatment of mild to moderate ulcerative colitis. Is there a benefit to continuing it once biological or immunomodulator therapy is initiated?Alimentary Pharmacology & Therapeutics (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 29, 2021 Category: Surgery Tags: Gastroenterology Journal Article Source Type: news

Dietary Intake in Adults With Inflammatory Bowel Disease Dietary Intake in Adults With Inflammatory Bowel Disease
This review aims to provide clarity about the dietary intake of adults with inflammatory bowel disease. How does it compare to that of healthy individuals?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 27, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Crohn's disease symptoms: The sign on your skin you could have the lifelong condition
CROHN'S disease is a lifelong condition where parts of the digestive system become inflamed. There are several symptoms to be aware of, including some which could occur on your skin. (Source: Daily Express - Health)
Source: Daily Express - Health - September 26, 2021 Category: Consumer Health News Source Type: news

Do you suffer with IBS? Your symptoms could be a sign of a more serious condition - expert
IRRITABLE bowel syndrome causes abdominal symptoms that include constipation, diarrhoea, or both. However, the condition does not damage a person's bowel like ulcerative colitis or Crohn's disease can. Symptoms can consist of flare ups that can cause excruciating pain and can make going about your daily life uncomfortable. For years, IBS has often been diagnosed before another, more serious condition. (Source: Daily Express - Health)
Source: Daily Express - Health - September 25, 2021 Category: Consumer Health News Source Type: news

Can Cannabis Help Your Gut?
When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - September 23, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Source Type: news

Statins can lower cholesterol - but a study has found another surprising health benefit
STATINS are a group of medicines that can help lower the level of cholesterol in the blood. Satins can also be taken to prevent heart disease, including heart attacks and strokes. Now, a new study has found that the cheap pills may also help treat ulcerative colitis. (Source: Daily Express - Health)
Source: Daily Express - Health - September 18, 2021 Category: Consumer Health News Source Type: news

Surveillance, Management of Colorectal Dysplasia in IBD Surveillance, Management of Colorectal Dysplasia in IBD
The American Gastroenterological Association provides 14 best practices regarding the prevention, detection, and management of colorectal dysplasia in patients with inflammatory bowel disease.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 17, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Statin Cholesterol Drugs May Help Fight Ulcerative Colitis
Title: Statin Cholesterol Drugs May Help Fight Ulcerative ColitisCategory: Health NewsCreated: 9/16/2021 12:00:00 AMLast Editorial Review: 9/17/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - September 17, 2021 Category: Nutrition Source Type: news

Statins don't just lower cholesterol! Study finds cheap pills may also help treat ulcerative colitis
Stanford University researchers have found that atrorvastatin - sold under the name Lipitor for just 54p a pill - slashes the risk of being hospitalised with the painful condition by half. (Source: the Mail online | Health)
Source: the Mail online | Health - September 16, 2021 Category: Consumer Health News Source Type: news

Statins may be an effective treatment for ulcerative colitis, study finds
Statins, the cholesterol-lowering drugs, may also help treat the symptoms of ulcerative colitis, a study published by the Journal of the American Medical Informatics Association found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - September 16, 2021 Category: Consumer Health News Source Type: news

Crohn’s disease: Pain felt on a certain area of the tummy could be a warning symptom
CROHN'S disease typically appears in younger people - often in their late teens, 20s or early 30s. However, the condition can also occur at any age. The location of your pain is a major warning sign, indicating your risk. (Source: Daily Express - Health)
Source: Daily Express - Health - September 13, 2021 Category: Consumer Health News Source Type: news

Subcutaneous Vedolizumab Appears to Be Effective Maintenance Therapy in Crohn's Disease Subcutaneous Vedolizumab Appears to Be Effective Maintenance Therapy in Crohn's Disease
Subcutaneous vedolizumab appears to be an effective and safe maintenance therapy for some patients with moderate to severe active Crohn's disease, according to results of a phase-3 trial.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 10, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Fecal Transplants: a New Treatment for IBD
Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV ste...
Source: TIME: Health - September 9, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Disease feature Source Type: news

Screen for Primary Sclerosing Cholangitis in IBD? Screen for Primary Sclerosing Cholangitis in IBD?
About 2% of patients with inflammatory bowel diseases will develop primary sclerosing cholangitis, with a higher prevalence in men than women, according to a new analysis.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 7, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

VARSITY: Better Outcomes With Vedolizumab Than Adalimumab in UC VARSITY: Better Outcomes With Vedolizumab Than Adalimumab in UC
In patients with moderate to severe ulcerative colitis, treatment with vedolizumab leads to better histologic outcomes than treatment with adalimumab, according to findings from the VARSITY trial.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 3, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

New COVID-Related GI Symptoms Common in IBD Patients New COVID-Related GI Symptoms Common in IBD Patients
International registry data show new onset of GI symptoms is common in inflammatory bowel disease (IBD) patients with COVID-19 regardless of IBD disease status.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 3, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

What Triggers Crohns Disease
What Triggers Crohn's Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 31, 2021 Category: General Medicine Source Type: news

Early Infliximab Could Change the Course of Crohn's Disease Early Infliximab Could Change the Course of Crohn's Disease
Starting infliximab early after diagnosis boosts the chance of achieving endoscopic remission and reduces the development of stenosis over the next 2 years, report clinicians from Germany.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 27, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Ultrasound Detects Ulcerative Colitis Disease Activity
FRIDAY, Aug. 27, 2021 -- A new ulcerative colitis intestinal ultrasound (UC-IUS) index shows strong correlation with endoscopy for detection of disease activity, according to a study published in the August issue of the Journal of Crohn's and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 27, 2021 Category: Pharmaceuticals Source Type: news

Outcome Measure Developed for Crohn's Perianal Fistula
WEDNESDAY, Aug. 25, 2021 -- A patient-reported outcome measure (PROM) has been developed for Crohn's perianal fistula, which has good internal consistency, excellent stability, and good responsiveness and construct validity, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 25, 2021 Category: Pharmaceuticals Source Type: news

InDex Pharmaceuticals receives FDA clearance to start the phase III study CONCLUDE with cobitolimod
STOCKHOLM, Aug. 24, 2021 -- (Healthcare Sales & Marketing Network) -- InDex Pharmaceuticals Holding AB (publ) today announced that the U.S. Food and Drug Administration (FDA) has given clearance to start the phase III clinical study CONCLUDE in the United... Biopharmaceuticals, Gastroenterology, FDA InDex Pharmaceuticals, cobitolimod, ulcerative colitis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 24, 2021 Category: Pharmaceuticals Source Type: news

Some Antibiotics May Affect Immunogenicity in IBD Some Antibiotics May Affect Immunogenicity in IBD
The risk for antidrug antibodies during antitumor necrosis factor therapy in patients with inflammatory bowel disease may be reduced with the appropriate choice of antibiotics, according to a new study.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 24, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

At-Home Fecal Calprotectin Test for IBD Shows Real-World Efficacy At-Home Fecal Calprotectin Test for IBD Shows Real-World Efficacy
The first study of its kind revealed the testing to have high patient compliance and robust sensitivity, boosting hopes for the future of home monitoring in inflammatory bowel disease (IBD).Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 24, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Adalimumab Biosimilar on Par With Original in Crohn's Disease Adalimumab Biosimilar on Par With Original in Crohn's Disease
For patients with moderate to severe active Crohn's disease, the adalimumab biosimilar BI 695501 from Boehringer Ingelheim proved as safe and effective as the original, AbbVie's Humira, in the phase-3 VOLTAIRE-CD study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 20, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Persistence With Biologics in Inflammatory Bowel Diseases Persistence With Biologics in Inflammatory Bowel Diseases
This study aimed to analyze persistence of biological agents in Crohn's disease and ulcerative colitis. What factors might influence treatment persistence?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 18, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Ulcerative colitis: Three gastrointestinal symptoms indicating risk - medicines to avoid
ULCERATIVE colitis is an inflammatory condition which can cause painful flare-ups and symptoms. How can you know if you may be suffering with the condition and, if so, what medication is best to avoid to reduce prolonging pain? (Source: Daily Express - Health)
Source: Daily Express - Health - August 17, 2021 Category: Consumer Health News Source Type: news

Efficacy of Escalated Anti-TNF Therapy in Crohn's Disease Efficacy of Escalated Anti-TNF Therapy in Crohn's Disease
Is dose escalation of anti-TNF therapy effective for reestablishing clinical response in Crohn's disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 16, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Tofacitinib As Salvage Therapy for Refractory Severe UC Tofacitinib As Salvage Therapy for Refractory Severe UC
In a cohort of patients hospitalized with a severe flare of ulcerative colitis, rescue therapy with tofacitinib avoided colectomy in a substantial proportion of cases.Alimentary Pharmacology & Therapeutics (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - August 11, 2021 Category: Surgery Tags: Gastroenterology Journal Article Source Type: news

IBD: COVID-19 Vaccination Still Effective in Immunosuppressed IBD: COVID-19 Vaccination Still Effective in Immunosuppressed
In a real-world setting, full vaccination against SARS-CoV-2 was more than 80% effective at reducing infection in people with inflammatory bowel disease who were taking immunosuppressive medications.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 7, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

IBD Risk Rises With Higher Ultraprocessed Food Intake IBD Risk Rises With Higher Ultraprocessed Food Intake
Certain categories of food, including white meat, dairy, and fruit, were not associated with inflammatory bowel disease (IBD) risk.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 6, 2021 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

How Is Crohn's Different From IBS?
Title: How Is Crohn's Different From IBS?Category: Diseases and ConditionsCreated: 8/3/2021 12:00:00 AMLast Editorial Review: 8/3/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 3, 2021 Category: Nutrition Source Type: news

Is Pancolitis the Same as Ulcerative Colitis?
Title: Is Pancolitis the Same as Ulcerative Colitis?Category: Diseases and ConditionsCreated: 8/3/2021 12:00:00 AMLast Editorial Review: 8/3/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 3, 2021 Category: Nutrition Source Type: news

How Do You Get Diagnosed with Ulcerative Colitis
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 28, 2021 Category: General Medicine Source Type: news

VTE Risk Up for Children With Inflammatory Bowel Disease
Venous thromboembolism occurred less often for those with Crohn disease versus ulcerative colitis (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 27, 2021 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pediatrics, Pharmacy, Journal, Source Type: news