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Mucosal healing: An objective measure of disease activity?
(Boston University School of Medicine) The absence of inflammatory and ulcerative lesions in all segments of the colon, also known as mucosal healing, should be the end goal in treating patients with ulcerative colitis according to an editorial in the journal Gastrointestinal Endoscopy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

Can Fish Oil Help Reading?
Discussion Fats and fatty acids are essential for good human health. Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet. Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature. Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Source: PediatricEducation.org - November 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Medical News Today: What you need to know about pancolitis
A look at pancolitis, a form of ulcerative colitis affecting the intestine. Included is information on flare-ups and complications of the condition. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

New study finds smoking causes inflammation in the bowel, resulting in ailments such as Crohn's disease
(Natural News) The health care industry has long established that smoking may exacerbate the risk of developing Crohn’s disease, but the mechanism behind the connection has remained unclear within the scientific community. However, a recent animal study in Frontiers in Immunology may provide a better overview about the role of smoking on disease onset. A team of researchers... (Source: NaturalNews.com)
Source: NaturalNews.com - November 16, 2017 Category: Consumer Health News Source Type: news

Tipping the balance: How one strain of bacteria affects its neighbors in Crohn's disease
(American Association for the Advancement of Science) A new study suggests a single strain of bacteria can reconfigure entire communities of microbes that make up the gut microbiota. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 15, 2017 Category: Infectious Diseases Source Type: news

Sex differences a rich field for UCLA multiple sclerosis researcher
As a child, Dr. Rhonda Voskuhl had terrible asthma, was often sick and had to get weekly allergy shots. She wondered why her body was so reactive to pollen, cats, wheat and eggs — her throat would swell, breathing became more difficult and her skin developed a rash. A frequent visitor to the doctor’s office, she had “a wonderful doctor who made me feel so much better.”It ’s no surprise, then, that Voskuhl grew up to become a doctor. Today, Voskuhl directs UCLA’s multiple sclerosis program and is the Jack H. Skirball professor of Multiple Sclerosis Research. She’s wrapping up one cl...
Source: UCLA Newsroom: Health Sciences - November 13, 2017 Category: Universities & Medical Training Source Type: news

Study: Patient engagement, clinical support platform improves IBD quality of care
A software platform developed at Mount Sinai comprising of a mobile app for patients and a decision support dashboard for practitioners can improve inflammatory bowel disease (IBD) patients ’ quality of care, according to clinical data recently presented at the Advances in Inflammatory Bowel Diseases Conference. (Source: mobihealthnews)
Source: mobihealthnews - November 13, 2017 Category: Information Technology Source Type: news

UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses a...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news

Medical News Today: What is left-sided colitis?
Left-sided colitis is a form of ulcerative colitis that affects the left side of the colon, causing a range of gastrointestinal symptoms. Learn more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 8, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Colon cancer breakthrough could lead to prevention - and the foods that can help
Colon cancer, Crohn's, and other diseases of the gut could be better treated - or even prevented - thanks to a new link between inflammation and a common cellular process, established by the University of Warwick. Led by Dr Ioannis Nezis at Warwick's School of Life Sciences, new research demonstrates that autophagy - an essential process whereby cells break down and recycle harmful or damaged elements within themselves to keep our bodies healthy - causes tissue inflammation when dysfunctional, which in turn leaves us susceptible to harmful diseases, particularly in the gut. (Source: World Pharma News)
Source: World Pharma News - November 8, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Takeda, Portal Instruments ink $100m deal to combine biologics and needle-free drug delivery
Takeda Pharmaceutical (TYO:4502) and Portal Instruments said today that the pair inked a collaboration to develop and commercialize Portal’s needle-free drug delivery device with Takeda’s biologic medicines. The first development program is slated to combine Takeda’s monoclonal antibody for adults with moderately- to severely-active ulcerative colitis or Crohn’s disease with Portal’s technology. The investigational therapy is currently administered through intravenous infusion, according to Takeda. Get the full story at our sister site, Drug Delivery Business News. The post Take...
Source: Mass Device - November 7, 2017 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Pharmaceuticals Wall Street Beat portal instruments Takeda Pharmaceuticals Source Type: news

What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

X Factor's Lloyd Macey says singing helps Crohn's disease
The 23-year-old Welshman, who has reached the live finals of this year ’s competition, has told of his dramatic six-year battle with Crohn’s. (Source: the Mail online | Health)
Source: the Mail online | Health - November 5, 2017 Category: Consumer Health News Source Type: news

New colon cancer breakthrough may lead to prevention
Researchers at the University of Warwick have found that a natural body process can cause inflammation, increasing the risk of colon cancer and Crohn's disease. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 3, 2017 Category: Consumer Health News Source Type: news

Medical News Today: The 10 best Crohn's disease blogs
Crohn's disease blogs can be a useful source of educational information on the condition and contain tips and accounts from individuals with the disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

New insights into the release of molecules involved in inflammatory diseases
(Instituto Gulbenkian de Ciencia) In a recent study published in Cell Reports, a research team led by Colin Adrain, from the Instituto Gulbenkian de Ci ê ncia (IGC, Portugal), discovered the mechanism that controls the release of important molecules that trigger the inflammatory response during the clearance of infections. When this machinery is deregulated it can contribute to important chronic diseases such as inflammatory bowel disease, arthritis, and cancer. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 2, 2017 Category: Biology Source Type: news

Colon cancer breakthrough could lead to prevention -- and the foods that can help
(University of Warwick) Colon cancer, Crohn's, and other diseases of the gut could be better treated -- or even prevented -- thanks to a new link between inflammation and a common cellular process, established by the University of Warwick. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 2, 2017 Category: Cancer & Oncology Source Type: news

Crohn's: Smoking can cause agonising bowel condition that brings misery to thousands
SMOKING can trigger an agonising digestive condition that blights the lives of tens of thousands of Britons, according to new research. (Source: Daily Express - Health)
Source: Daily Express - Health - October 31, 2017 Category: Consumer Health News Source Type: news

Smoking cigarettes may cause Crohn's disease
Scientists at Kyung Hee University, Seoul, discovered mice who inhaled cigarette smoke showed signs of intestinal inflammation - a sign of Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - October 31, 2017 Category: Consumer Health News Source Type: news

New data suggest Roche ’s etrolizumab can provide clinically meaningful improvements in the treatment of two of the most common forms of inflammatory bowel disease
Roche today announced data from two ongoing phase III trials evaluating etrolizumab in patients with inflammatory bowel disease (IBD). (Source: Roche Investor Update)
Source: Roche Investor Update - October 31, 2017 Category: Pharmaceuticals Source Type: news

Research suggests new way to treat inflammatory gut disease and prevent rejection of bone marrow transplants
(NYU Langone Health / NYU School of Medicine) A new study explains how a widely used drug is effective against inflammatory bowel disease and rejection of bone marrow transplants, while suggesting another way to address both health issues. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 31, 2017 Category: Biology Source Type: news

Smoking may cause inflammatory bowel disease
(Frontiers) A new study shows for the first time a direct effect of cigarette smoke on bowel inflammation. The researchers find that mice exposed to cigarette smoke develop a type of colitis resembling Crohn's disease. The researchers also identified a specific immune cell responsible for the effect. These findings could help scientists develop new treatments for inflammatory bowel diseases, such as Crohn's disease, and increase awareness among smokers of their risk for colitis. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 31, 2017 Category: International Medicine & Public Health Source Type: news

Hydrogel-grown tissues speed wound healing in mouse colon
An injectable hydrogel grew intestine-like tissues and accelerated wound healing in the intestines of mice. The findings suggest new treatments for diseases such as inflammatory bowel disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - October 31, 2017 Category: Consumer Health News Source Type: news

A 17-year-old with schizophrenia and uncontrollable anxiety after a suicide attempt - Blain K, Magid M.
A 17-year-old boy with a history of schizophrenia, asthma, and Crohn's disease was brought to the emergency department (ED) by his aunt after a suicide attempt in which he lit his bedroom on fire. After 20 minutes in the burning room, he aborted the attemp... (Source: SafetyLit)
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Upstate discovery advances understanding of inflammatory bowel disease
Study shows evidence that patients with IBD lack appropriate amounts of key protein. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - October 28, 2017 Category: Universities & Medical Training Source Type: news

The selfie campaign urging you to 'Get Your Belly Out'
Meet the women who set up the campaign for people with Crohn's and colitis. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 25, 2017 Category: Consumer Health News Source Type: news

Protein regulates vitamin A metabolic pathways, prevents inflammation
(Case Western Reserve University) A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation. The discovery links diet to inflammatory diseases, like Crohn's disease and inflammatory bowel syndromes, and could inform nutritional interventions. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 23, 2017 Category: Biology Source Type: news

Celgene Provides Update on GED-0301 (mongersen) Inflammatory Bowel Disease Program
SUMMIT, N.J.--(Healthcare Sales & Marketing Network)-- Celgene Corporation (NASDAQ: CELG) today announced that the GED-0301 (mongersen) phase III REVOLVE trial (CD-002) in Crohn's disease (CD) and the extension trial (SUSTAIN, CD-004) will discontinue. Cel... Biopharmaceuticals, Gastroenterology Celgene, mongersen, REVOLVE trial, Crohn's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 20, 2017 Category: Pharmaceuticals Source Type: news

Research predicts increase in inflammatory bowel disease in developing world
(University of Calgary) For the last century, inflammatory bowel disease (IBD) has been a challenge for patients and the medical community in the western world. New research published today in The Lancet by Dr. Gilaad Kaplan shows that countries outside the western world may now be facing the same pattern of increasing IBD rates. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 20, 2017 Category: International Medicine & Public Health Source Type: news

Celgene abandons Crohn's drug trials, shares drop
(Reuters) - Celgene Corp said it would abandon testing a drug to treat Crohn's disease, in a major setback to the U.S. biotechnology company's pipeline amid attempts to lower dependence on its mainstay Revilimid. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Celgene to stop testing Crohn's drug, shares drop
(Reuters) - Celgene Corp said it would abandon testing a drug to treat Crohn's disease, an inflammatory bowel disease, following a risk-benefit analysis by a data monitoring committee, in a major setback to the drugmaker's pipeline. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Celgene abandons Crohn's disease drug trials
(Reuters) - Celgene Corp said on Thursday it would stop two studies of its drug for an inflammatory bowel disease and would not begin a third, following a recommendation by a data monitoring committee. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation
Intestinal colonization by bacteria of oral origin has been correlated with several negative health outcomes, including inflammatory bowel disease. However, a causal role of oral bacteria ectopically colonizing the intestine remains unclear. Using gnotobiotic techniques, we show that strains of Klebsiella spp. isolated from the salivary microbiota are strong inducers of T helper 1 (TH1) cells when they colonize in the gut. These Klebsiella strains are resistant to multiple antibiotics, tend to colonize when the intestinal microbiota is dysbiotic, and elicit a severe gut inflammation in the context of a genetically suscepti...
Source: ScienceNOW - October 19, 2017 Category: Science Authors: Atarashi, K., Suda, W., Luo, C., Kawaguchi, T., Motoo, I., Narushima, S., Kiguchi, Y., Yasuma, K., Watanabe, E., Tanoue, T., Thaiss, C. A., Sato, M., Toyooka, K., Said, H. S., Yamagami, H., Rice, S. A., Gevers, D., Johnson, R. C., Segre, J. A., Chen, K., Tags: Immunology, Microbiology reports Source Type: news

Continuous Clinical Response in Ulcerative Colitis Continuous Clinical Response in Ulcerative Colitis
Continuous clinical response has emerged as a useful target in the management of ulcerative colitis. Can it be feasibly integrated into clinical practice as a patient-reported outcome?Clinical Gastroenterology and Hepatology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 10, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Fungus may play key role in Crohn's, chronic intestinal inflammation
Researchers at Case Western University have found that fungi in combination with bacteria play a vital role in chronic intestinal inflammation disorders. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: New IBD treatments may combine antifungals and probiotics
A review suggests that gut fungi, along with bacteria, play a key role in gut health, and new treatments for IBD may combine antifungals with probiotics. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 4, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Seres reports positive Phase Ib trial results of SER-287 in UC patients
US-based Seres Therapeutics has reported positive topline results from a Phase Ib placebo-controlled induction trial of SER-287 in patients with mild-to-moderate ulcerative colitis (UC), who were failing current therapies. (Source: Drug Development Technology)
Source: Drug Development Technology - October 2, 2017 Category: Pharmaceuticals Source Type: news

High-precision radiotherapy for prostate cancer 'shows promise'
Conclusion This study shows some promising results for targeted pelvic lymph node radiotherapy for men with advanced localised prostate cancer. However, these results can only be treated as preliminary findings for now. This was an early-stage trial that aimed to investigate whether the treatment approach is safe and to get an idea of what doses may be suitable for assessment in further trials. Although it can give an indication of effectiveness, this was not the main aim of the study. Men were not randomised to a treatment group, which means there may have been some differences in the cancers or patient characteristics of...
Source: NHS News Feed - September 26, 2017 Category: Consumer Health News Tags: Cancer Source Type: news

IBD in Childhood Raises Cancer Risk IBD in Childhood Raises Cancer Risk
The introduction of new drug therapies for inflammatory bowel disease does not seem to have changed the increased risk for cancer in this patient population.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 25, 2017 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Belfast bodybuilder left mute by six stone weight loss
Terri Keith, 30, of Belfast, went from a size 16 to a size 6 in just 10 months but The weight loss left her with malnutrition and made  her ulcerative colitis worse. Now she is a champion bodybuilder. (Source: the Mail online | Health)
Source: the Mail online | Health - September 25, 2017 Category: Consumer Health News Source Type: news

Drug targeting technique could aid therapies for immune diseases
(University of Edinburgh) A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response. The research from the University of Edinburgh could help people affected by conditions such as arthritis and inflammatory bowel diseases, where the body's own immune system mistakenly attacks healthy tissues. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 25, 2017 Category: International Medicine & Public Health Source Type: news

Purple potatoes may cut your risk of developing colon cancer and inflammatory bowel diseases, new research says
(Natural News) The first experience I had with “purple” potatoes was earlier this summer when my bride and I had several Army buddies over for a social gathering, and one of our guests brought a multi-colored potato salad as her contribution to the food table. I was flabbergasted, as was my friend’s hubby, who told... (Source: NaturalNews.com)
Source: NaturalNews.com - September 24, 2017 Category: Consumer Health News Source Type: news

Inflammatory Spinal Disorders Common in IBD Patients Inflammatory Spinal Disorders Common in IBD Patients
Ankylosing spondylitis (AS), axial spondyloarthritis (SpA) and inflammatory back pain are common in inflammatory bowel disease (IBD) patients two decades after IBD diagnosis, according to findings from the IBSEN study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 22, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Purple potatoes may slash risk of colon cancer and IBD
Pigs fed purple potatoes had six times reduced levels of a damaging protein that fuels tumours and other inflammatory bowel diseases, a study by Pennsylvania State University found. (Source: the Mail online | Health)
Source: the Mail online | Health - September 22, 2017 Category: Consumer Health News Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Researchers think chronic inflammation in gastrointestinal tract may be driving force (Source: Cancercompass News: Colorectal Cancer)
Source: Cancercompass News: Colorectal Cancer - September 22, 2017 Category: Cancer & Oncology Source Type: news

Medical News Today: Cancer risk higher in children with inflammatory bowel disease
Researchers find that childhood inflammatory bowel disease is linked to higher risk of cancer - especially gastrointestinal - that persists into adulthood. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 21, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Researchers think chronic inflammation in gastrointestinal tract may be driving force (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - September 21, 2017 Category: Cancer & Oncology Tags: Gastroenterology, Hepatology, Oncology, Pediatrics, Rheumatology, News, Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Researchers think chronic inflammation in gastrointestinal tract may be driving forceSource: HealthDay Related MedlinePlus Pages: Cancer in Children, Crohn's Disease, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 21, 2017 Category: Consumer Health News Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
THURSDAY, Sept. 21, 2017 -- Children with inflammatory bowel disease (IBD) face an increased risk of cancer, a new study claims. The risk persists into adulthood, and is especially elevated for gastrointestinal cancers, the researchers added. The... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 21, 2017 Category: General Medicine Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Title: Inflammatory Bowel Disease May Raise Cancer Risk in KidsCategory: Health NewsCreated: 9/21/2017 12:00:00 AMLast Editorial Review: 9/21/2017 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - September 21, 2017 Category: Cancer & Oncology Source Type: news