https://www.sierraclub.org/sierra/PFAS-toxin-every-household-states-sue-chemical-companies
Medical studies have linked PFAS in drinking water to kidney cancer, testicular cancer, thyroid disease, ulcerative colitis, pancreatic cancer and birth defects.08/13/2018 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - August 13, 2018 Category: Urology & Nephrology Source Type: news

What is Crohn’s disease? Symptoms and treatments revealed - are you at risk?
CROHN ’S DISEASE is a type of inflammatory bowel disease , where parts of the digestive system become inflamed. What are the signs and symptoms of the lifelong condition, and how is it treated? (Source: Daily Express - Health)
Source: Daily Express - Health - August 12, 2018 Category: Consumer Health News Source Type: news

New mother, 29, developed flesh-eating infection after childbirth
Inflammatory bowel disease is excruciating. Carrying a child can be, too.  Suffering both is overwhelming, to put it mildly. But that was just the start for Connecticut-based Sophie Green, 29. (Source: the Mail online | Health)
Source: the Mail online | Health - August 10, 2018 Category: Consumer Health News Source Type: news

Adalimumab Appears Safe for Treating Pediatric Patients With Autoimmune Disease Adalimumab Appears Safe for Treating Pediatric Patients With Autoimmune Disease
Adalimumab appears to be safe for treating pediatric patients with polyarticular juvenile idiopathic arthritis (JIA), enthesitis-related arthritis (ERA), psoriasis and Crohn's disease (CD), according to data from company-sponsored clinical trials.Reuters Health Information (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - August 10, 2018 Category: Allergy & Immunology Tags: Pediatrics News Source Type: news

Erectile-Dysfunction Prescriptions More Common in Men With IBD Erectile-Dysfunction Prescriptions More Common in Men With IBD
Men with inflammatory bowel diseases (IBD) are more likely to fill prescriptions for erectile dysfunction (ED) medications compared to men without IBD, according to a Danish registry study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 8, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Boston Children's Hospital accelerates genomic sequencing to expand existing genomic database
(Boston Children's Hospital) Boston Children's Hospital has embarked on a strategic initiative to expand its research genomics gateway, with plans to sequence the DNA of 3,000 patients with epilepsy or inflammatory bowel disease and their family members. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 7, 2018 Category: International Medicine & Public Health Source Type: news

Impact of Opioid Epidemic on IBD: Patients Are at Risk Impact of Opioid Epidemic on IBD: Patients Are at Risk
The impact of the opioid epidemic in patients with ulcerative colitis and Crohn disease is front and center at DDW 2018.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 6, 2018 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Medical News Today: Is postpartum gas normal?
It is common for a person to experience increased flatulence, or postpartum gas, after giving birth. For most people, the gas will eventually go away on its own. Possible causes of postpartum gas include a pelvic floor injury, constipation, diet and lifestyle factors, and inflammatory bowel disease. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 6, 2018 Category: Consumer Health News Tags: Pregnancy / Obstetrics Source Type: news

Stem cell transplants to be used in treating Crohn's disease
(Queen Mary University of London) A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn's disease -- a painful and chronic intestinal disease which affects at least 115,000 people in the UK. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 5, 2018 Category: International Medicine & Public Health Source Type: news

European Union Clears Tofacitinib for Ulcerative Colitis European Union Clears Tofacitinib for Ulcerative Colitis
The JAK inhibitor is indicated for adults with moderately to severely active ulcerative colitis who have failed to respond adequately to or are intolerant of other therapies.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - August 2, 2018 Category: Consumer Health News Tags: Gastroenterology News Alert Source Type: news

IL-23-Specific Antibody Ups Response in Anti-TNF-Refractory Crohn's
(MedPage Today) -- Subcutaneous risankizumab also looks promising for maintaining remission (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - August 2, 2018 Category: Primary Care Source Type: news

Increased Flu Risk With Inflammatory Bowel Disease Increased Flu Risk With Inflammatory Bowel Disease
People with inflammatory bowel disease (IBD) face a significantly increased risk of influenza, according to a retrospective database study.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 2, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New Crohn Disease Management Guidelines: Top Five Takeaways New Crohn Disease Management Guidelines: Top Five Takeaways
Recently published guidelines by the American College of Gastroenterology provide recommendations on the management of Crohn disease. Dr David Johnson shares his perspective on some of the highlights.Medscape Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 1, 2018 Category: Consumer Health News Tags: Gastroenterology Commentary Source Type: news

Study Supports Safety of Infliximab in Pregnancy Study Supports Safety of Infliximab in Pregnancy
New registry data should help reassure women with Crohn's disease (CD) who need to continue infliximab during pregnancy that it won't harm their baby.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 30, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

RedHill BioPharma has positive results from Crohn's disease trial
Israel's RedHill Biopharma said on Monday it had positive safety and efficacy results from a late-stage clinical trial with its treatment for Crohn's disease called RHB-104. (Source: Reuters: Health)
Source: Reuters: Health - July 30, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Methotrexate No Better Than Placebo for Steroid-Free Response, Remission in UC Methotrexate No Better Than Placebo for Steroid-Free Response, Remission in UC
Subcutaneous methotrexate (MTX) may not work better than placebo as maintenance therapy for ulcerative colitis (UC), researchers have found.Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 28, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Predictors of suicidal ideation among IBD outpatients - Hashash JG, Vachon A, Ramos Rivers C, Regueiro MD, Binion DG, Altman L, Williams C, Szigethy E.
BACKGROUND: Suicidal ideation (SI) is understudied in inflammatory bowel diseases (IBD). We aim to determine SI rates among IBD outpatients and to evaluate predictors of SI. MATERIALS AND METHODS: This is a prospective observational study of consec... (Source: SafetyLit)
Source: SafetyLit - July 27, 2018 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Sustained Response to Golimumab Predicts Good Outcomes in Ulcerative Colitis Sustained Response to Golimumab Predicts Good Outcomes in Ulcerative Colitis
Continuous clinical response (CCR) to golimumab treatment is associated with favorable outcomes in patients with moderate to severe ulcerative colitis (UC), according to a post hoc analysis of the PURSUIT-M trial.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - July 26, 2018 Category: Surgery Tags: Gastroenterology News Source Type: news

Bioelectronics: A New era in Medical Care Is on the Horizon
Bioelectronics, generally defined, isn't new. Doctors Rune Elmqvist and Ake Senning implanted the first pacemaker in 1958. FDA approved the first spinal cord stimulator (SCS) in 1989. While both solutions continue to help patients worldwide, smaller, more advanced technology has pushed bioelectronics into a new era. Researchers have developed novel methods to use electrical impulses to regulate the brain and/or nervous system, resulting in highly targeted, effective treatment. "While SCS benefits last as long as the device stimulates, and the pacemaker continually keeps the heart on path, we treat and hope to modify t...
Source: MDDI - July 25, 2018 Category: Medical Devices Authors: Heather R. Johnson Tags: Implants Electronics Source Type: news

Most Eligible IBD Patients Don't Get Shingles Vaccine Most Eligible IBD Patients Don't Get Shingles Vaccine
Just one in five patients with inflammatory bowel disease (IBD) who are eligible for the herpes zoster (HZ) vaccine actually receive it, according to new study in VA patients.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 24, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Novel Oral-targeted Therapies in Inflammatory Bowel Disease Novel Oral-targeted Therapies in Inflammatory Bowel Disease
This article presents an overview of recent clinical trials for next generation oral targeted medications that show promise in the management of inflammatory bowel disease.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 24, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Could Viruses Attacking The Microbiome Be Responsible For Inflammatory Bowel Disease?
Researchers have discovered a correlation between viruses and inflammation in a mouse model of inflammatory bowel disease. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 24, 2018 Category: Pharmaceuticals Authors: Victoria Forster, Contributor Source Type: news

Intestinal virus study shows major changes associated with inflammatory bowel disease
(North Carolina State University) Study comparing healthy and diseased mouse intestinal tracts shows unexpected changes in viral communities. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 24, 2018 Category: International Medicine & Public Health Source Type: news

Researchers find link between viruses, inflammatory bowel diseases
Viruses and inflammatory bowel diseases, including ulcerative colitis and Crohn's disease, have a key connection, according to a study with mice. (Source: Health News - UPI.com)
Source: Health News - UPI.com - July 23, 2018 Category: Consumer Health News Source Type: news

Supplements for IBS and IBD: 10 natural remedies to put out the fire in your gut
(Natural News) Studies have stated that around half of patients suffering from inflammatory bowel disease (IBD) or inflammatory bowel syndrome (IBS) take some form of nutritional supplement. Countless research emphasizes the importance of proper supplementation in the prevention, management, and treatment of both gastrointestinal disorders. That said, nutritionists vary in their opinion on which supplement... (Source: NaturalNews.com)
Source: NaturalNews.com - July 23, 2018 Category: Consumer Health News Source Type: news

Researchers find connection between viruses and inflammatory bowel disease
(University of Colorado Anschutz Medical Campus) A study led by a researcher at the University of Colorado Anschutz Medical Campus reveals a key connection between viruses and inflammatory bowel diseases like ulcerative colitis and Crohn's disease. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - July 23, 2018 Category: Infectious Diseases Source Type: news

IMI Launches New Antimicrobial Resistance Accelerator Programme as Part of Latest Calls for Proposals
A new Antimicrobial Resistance (AMR) Accelerator Programme is part of new Calls for proposals launched today by the Innovative Medicines Initiative (IMI). Of the other topics launched in the Calls, many address brain disorders (e.g. Alzheimer's disease, Parkinson's disease, Huntington's disease, major depression) and immune-mediated diseases (e.g. rheumatoid arthritis and lupus as well as inflammatory bowel diseases such as Crohn's and colitis, and skin diseases like dermatitis and psoriasis). (Source: eHealth News EU)
Source: eHealth News EU - July 18, 2018 Category: Information Technology Tags: Featured Open Calls Source Type: news

Unique BIR domain sets determine inhibitor of apoptosis protein-driven cell death and NOD2 complex signal specificity
The mammalian IAPs, X-linked inhibitor of apoptosis protein (XIAP) and cellular inhibitor of apoptosis protein 1 and 2 (cIAP1 and cIAP2), play pivotal roles in innate immune signaling and inflammatory homeostasis, often working in parallel or in conjunction at a signaling complex. IAPs direct both nucleotide-binding oligomerization domain-containing 2 (NOD2) signaling complexes and cell death mechanisms to appropriately regulate inflammation. Although it is known that XIAP is critical for NOD2 signaling and that the loss of cIAP1 and cIAP2 blunts NOD2 activity, it is unclear whether these three highly related proteins can ...
Source: Signal Transduction Knowledge Environment - July 17, 2018 Category: Science Authors: Chirieleison, S. M., Rathkey, J. K., Abbott, D. W. Tags: STKE Research Articles Source Type: news

AI accurately predicts effects of genetic mutations in biological dark matter
(Simons Foundation) A new machine learning framework, dubbed ExPecto, can predict the effects of genetic mutations in the so-called 'dark matter' regions of the human genome. ExPecto pinpoints how specific mutations can disrupt the way genes express throughout your body. Using the method, its creators computed the genetic ramifications of more than 140 million mutations in different tissues. The researchers also precisely pinpointed mutations potentially responsible for increasing the risk of several immune-related diseases, including Crohn's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2018 Category: International Medicine & Public Health Source Type: news

Obesity and Treatment Failure in Biologic-Treated UC Patients Obesity and Treatment Failure in Biologic-Treated UC Patients
How does obesity impact real world response to biological therapy in patients with ulcerative colitis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 12, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Uncovering the evolutionary history of IBD-associated colorectal cancer
(Queen Mary University of London) A team of researchers from Queen Mary University of London have reported the genetic events involved in the early development of bowel cancer in patients with inflammatory bowel disease (IBD). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 11, 2018 Category: Cancer & Oncology Source Type: news

Acetaminophen, NSAIDs and Risk of IBD Exacerbation Acetaminophen, NSAIDs and Risk of IBD Exacerbation
Does the use of NSAIDs or COX-2 inhibitors exacerbate Crohn's disease or ulcerative colitis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 10, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: What is dexamethasone?
Dexamethasone oral tablet is a prescription medication used to treat conditions such as inflammation, allergic reactions, ulcerative colitis, and adrenal insufficiency. It's available as a generic drug and as the brand-name drugs DexPak and Decadron. Learn about side effects, warnings, dosage, and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 10, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

C-11-based PET tracer could benefit arthritis patients
Carbon-11 (C-11) PET that targets translocator protein expression in the joint...Read more on AuntMinnie.comRelated Reading: Start-up to develop arthritis molecular imaging agent PET tracer may aid diagnosis of inflammatory bowel disease Immuno-PET tracer offers hope for early cancer treatment Novel PET tracer could help assess arthritis PET imaging could help personalize cancer treatment (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 9, 2018 Category: Radiology Source Type: news

Gender-bending chemical may cause inflammatory bowel disease
Researchers from Texas A&M University found that exposure to bisphenol A (BPA) causes the same inflammation and gut bacteria changes in mice that occur in Crohn's and ulcerative colitis patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 6, 2018 Category: Consumer Health News Source Type: news

Exposure to a gender-bending chemical found in bank notes may cause inflammatory bowel disease
Researchers from Texas A&M University found that exposure to bisphenol A (BPA) causes the same inflammation and gut bacteria changes in mice that occur in Crohn's and ulcerative colitis patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 6, 2018 Category: Consumer Health News Source Type: news

Aalto University Researchers Develop Plasmonic Biosensor That Can Distinguish Differences in Exosomes, Giving Clinical Laboratories New Tool for Spotting Disease in Human Blood with Naked Eye
Analysis performed by this new biosensor could help identify inflammatory bowel diseases, cancer, and other chronic diseases, and contribute to influencing the best treatment options, a critical aspect of personalized medicine Anatomic pathologists and clinical laboratories have long known that disease, as the saying goes, “is written in the blood.” How to spot the disease […] (Source: Dark Daily)
Source: Dark Daily - July 6, 2018 Category: Laboratory Medicine Authors: Michael Tags: Clinical Laboratory/Pathology Automation, Analyzers, Testing Systems Instruments & Equipment Laboratory Instruments & Laboratory Equipment Laboratory News Laboratory Operations Laboratory Pathology Laboratory Testing Aalto University anato Source Type: news

Texas A & M AgriLife study shows BPA risk factor for inflammatory bowel disease
(Texas A&M AgriLife Communications) A recent study in a preclinical model of inflammatory bowel disease shows dietary exposure to bisphenol-A, or BPA, found in polycarbonate plastics and epoxy resins, can increase mortality and worsen its symptoms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 5, 2018 Category: International Medicine & Public Health Source Type: news

Novel nanoSPECT/CT radionuclide could aid cancer therapy
Swedish and Dutch researchers are reporting early progress in combining nanoSPECT/CT...Read more on AuntMinnie.comRelated Reading: SNMMI: Early prostate cancer therapy extends lives SNMMI: New therapy aids patients with neuroendocrine tumors Novel PET tracer shows promise for neuroendocrine tumors PET tracer may aid diagnosis of inflammatory bowel disease New therapeutic agent could treat prostate cancer (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - July 3, 2018 Category: Radiology Source Type: news

Smartphone Apps for IBD Patients Plagued by Shortcomings Smartphone Apps for IBD Patients Plagued by Shortcomings
Most smartphone apps aimed at patients with inflammatory bowel disease (IBD) have severe shortcomings, including a lack of scientific support and clinical validation, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 28, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Medical News Today: Could treating these immune cells cure IBD?
By identifying a distinct group of CD4 T cells that create and perpetuate intestinal inflammation, scientists could be on track to finding a cure for IBD. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 28, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Becoming unglued: how a genetic variant may affect the gut barrier and contribute to inflammatory bowel disease
Researchers have found that a genetic variant may impart risk for inflammatory bowel disease (IBD) by disrupting the cellular “glue” that keeps the gut’s lining intact.  (Source: NIDDK News)
Source: NIDDK News - June 26, 2018 Category: Endocrinology Source Type: news

Bacterial enzyme implicated in inflammatory bowel disease
Using human samples and animal models, researchers have found that an enzyme produced by certain bacteria could disrupt the gut microbiome, potentially playing a significant role in the development of inflammatory bowel disease. (Source: NIDDK News)
Source: NIDDK News - June 26, 2018 Category: Endocrinology Source Type: news

Immune cells that create and sustain chronic inflammatory bowel disease identified
(University of Alabama at Birmingham) In preclinical experiments, Laurie Harrington and colleagues have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease. These cells could become potential therapeutic targets to ameliorate or cure Crohn's disease and ulcerative colitis. Furthermore, if this subset of CD4 T cells plays a similar role in other autoimmune diseases, such as Type 1 diabetes or rheumatoid arthritis, they could also be targets for therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 26, 2018 Category: International Medicine & Public Health Source Type: news

Cincinnati pharma firm inks deal that could be worth over $400M
Aerpio Pharmaceuticals Inc. revealed today that that company has signed a licensing agreement that could be worth more than $400 million. The Blue Ash-based firm (OTCQB: ARPO) will be paid $20 million up front by GB004 Inc. for an Aerpio stabilizer in development to treat inflammatory bowel disease.  GB004, a subsidiary of San Diego-based Gossamer Bio Inc., will pay up to $400 million for milestones linked to the development and c ommercialization of Aerpio’s hypoxia-inducible factor-1 alpha… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 25, 2018 Category: Pharmaceuticals Authors: Barrett J. Brunsman Source Type: news

Shedding Light on the Functional Genetic Architecture of Inflammatory Bowel Disease
Recent findings have uncovered two genetic variants that increase the risk for inflammatory bowel disease and also provided clues to their function. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news

Early source of irritable bowel syndrome discovered
(Michigan State University) Michigan State University scientists have identified an early cause of intestinal inflammation, one of the first stages of inflammatory bowel disease and irritable bowel syndrome, which afflict around 11 percent of the world's population. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 14, 2018 Category: International Medicine & Public Health Source Type: news

Psoriasis linked to gut health: Leaky gut could be caused by microbiome composition
(Natural News) There have been numerous studies linking gut health to all kinds of diseases, including – but not limited to – diabetes, obesity, and inflammatory bowel disease. Leaky gut among psoriasis patients can be added to that growing list, courtesy of a study published in Scientific Reports. For their study, the researchers used 52... (Source: NaturalNews.com)
Source: NaturalNews.com - June 13, 2018 Category: Consumer Health News Source Type: news

The Good Doctors Guide: Meet the best doctors for gall bladder and inflammatory bowel disease
Where are the hallmarks of a good doctor? Technical expertise and skill, of course — but someone who understands you, someone you trust, is also vital. (Source: the Mail online | Health)
Source: the Mail online | Health - June 7, 2018 Category: Consumer Health News Source Type: news

Genentech's gutsy move: Biotech giant snags potential half-billion-dollar deal with UK microbiome company
In its second microbiome deal over the past month, Genentech and partner Microbiotica will tap artificial intelligence to identify ways to use the gut's own environment to attack inflammatory bowel disease. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - June 6, 2018 Category: Biotechnology Authors: Ron Leuty Source Type: news