IIG Seminar - Pathogenic communications between the mouth and gut
Dr. Kamada ’ s laboratory is interested in understanding how the gut microbiota and host immunity interact in gastrointestinal health and disease. Specifically, they have focused on the mechanisms by which certain pathogenic members of commensal bacteria promote chronic intestinal inflammation that leads to the development of inflammatory bowel disease. Dr. Kamada and his group are investigating how potentially pathogenic members of commensal bacteria accumulate the gut and activate host immune cells. Likewise, Dr. Kamada is studying how beneficial commensal bacteria compete with these pathogenic bacteria and regulate in...
Source: Videocast - All Events - March 1, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Bioengineers create pH-sensing gut bacteria to diagnose inflammatory bowel disease.
Bioengineers create pH-sensing gut bacteria to diagnose inflammatory bowel diseaseThis is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 28, 2021 Category: Science Source Type: video
CC Grand Rounds: Contemporary Clinical Medicine: Great Teachers: Human Models of Inflammatory Bowel Disease (IBD)
For more information go tohttps://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 2/12/2020 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 22, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Gut reactions: host microbiome interactions in the intestine in health and disease
NIH Director's Wednesday Afternoon Lecture Series
The gastrointestinal tract is home to a large number and vast array of bacteria that play an important role in nutrition, immune-system development, and host defense. In inflammatory bowel disease there is a breakdown in this mutualistic relationship resulting in aberrant inflammatory responses to intestinal bacteria. Studies in model systems indicate that intestinal homeostasis is an active process involving a delicate balance between effector and immune suppressive pathways. For her presentation, Dr. Powrie will discuss bacterial pathways that promote intestinal homeostas...
Source: Videocast - All Events - March 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
Gut feelings: host microbiome interactions in health and disease
NIH Director's Wednesday Afternoon Lecture Series
Fiona Powrie is interested in the intestinal immune system ’ s ability to distinguish foreign microbes from the trillions of harmless bacteria that reside in our gut – and how this delicate balancing act breaks down in inflammatory bowel disease. Her work has identified suppressor ‘ regulatory T cells ’ that are crucial for gut homeostasis, as well as immune signals pivotal for chronic intestinal inflammation.For more information go tohttps://oir.nih.gov/wals/2017-2018/Air date: 3/14/2018 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 12, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video
CC Grand Rounds: Great Teachers: Very Early Onset Inflammatory Bowel Disease: Similar Yet Different from Adult-Onset Inflammatory Bowel Disease
For more information go tohttp://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 1/10/2018 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 21, 2017 Category: General Medicine Tags: Upcoming Events Source Type: video
Role and Regulation of the NLRP3 Inflammasome.
Immunology Interest Group
Gabriel Nuñez earned his M.D. degree from the University of Seville, Spain, in 1977. He received postdoctoral training in Immunology at the University of Texas Southwestern Medical Center, Dallas (1979–1984) and residency training in Anatomical Pathology at Washington University in St Louis (1985–1990). In 1987, he joined the laboratory of Stanley Korsmeyer at Washington University, where he studied the function of the anti-apoptotic protein BCL-2. In 1991, he joined the Department of Pathology at the University of Michigan in Ann Arbor as an Assistant Professor and was promoted to full Prof...
Source: Videocast - All Events - March 14, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video
Demystifying Medicine 2016: The Intestinal Microbiome and Inflammatory Bowel Disease
Presented by: Yasmine Belkaid, PhD, NIAID, NIH and Warren Strober, MD, NIAID, NIHCategory: Demystifying MedicineAired date: 02/09/2016 (Source: Videocast - All Events)
Source: Videocast - All Events - February 10, 2016 Category: Journals (General) Tags: Past Events Source Type: video
Demystifying Medicine 2016: The Intestinal Microbiome and Inflammatory Bowel Disease
Demystifying Medicine is an annual course from January to May designed to help bridge the gap between advances in biology and their application to major human diseases. The course includes presentation of patients, pathology, diagnosis, and therapy in the context of major disease problems and current research, primarily directed toward Ph.D. students, fellows, and staff. All are invited.For more information go to https://demystifyingmedicine.od.nih.gov/
Air date: 2/9/2016 4:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - December 1, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
NIH Research Festival: A Celebration of Intramural Science Plenary Session III: Chronic Inflammation
Most of the NIH institutes and centers are involved in studies for which chronic inflammation is a common denominator. Allergies, asthma, heart and circulatory disease, rheumatoid arthritis, inflammatory bowel disease, celiac disease, some cancers, multiple sclerosis, and possibly Alzheimer’s. These are just a few debilitating diseases that can originate partly or entirely from the immune system’s aggressive response to perceived harmful stimuli. Aging itself has been described as the totality of a lifetime of chronic inflammation. Better understanding the causes and control of chronic inflammation thus can lead to pro...
Source: Videocast - All Events - September 15, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
Data-Driven Precision Medicine
National Library of Medicine Informatics Lecture Series
There is an urgent need to translate genome-era discoveries into clinical utility, but the difficulties in making bench-to-bedside translations have been well described. The nascent field of translational bioinformatics may help. Dr. Butte's lab builds and applies computational tools to convert hundreds of trillions of points of molecular, clinical, and epidemiological data collected by researchers and clinicians worldwide over the past decade, now commonly known as “big data”, into new diagnostics, therapeutics, and insights into rare and common diseases. Dr. Bu...
Source: Videocast - All Events - May 6, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
Inflammation, dysbiosis and chronic disease
Wednesday Afternoon Lecture Series
Dysregulation of the immune system and host-microbiota interaction has been associated with the development of a variety of inflammatory as well as metabolic diseases such as obesity and diabetes. Recent studies in Dr. Flavell's laboratory have elucidated the important function of inflammasomes as steady-state sensors and regulators of the gut microbiota. Mice with a disrupted inflammasome pathway have been shown to develop a colitogenic microbial community, which results in exacerbation of chemical-induced colitis and diet-induced steatohepatitis, obesity and type 2 diabetes.
These d...
Source: Videocast - All Events - March 17, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
CC Grand Rounds: (1) Myelokathectic Immunodeficiency Disorders: Tales from the Clinic (2) Ulcerative Colitis: An Atypical Th2 Disorder Mediated by NKT Cells
Presented by: (1) Philip M. Murphy, MD, Chief, Laboratory of Molecular Immunology, NIAID, NIH (2) Warren Strober, MD, Chief, Mucosal Immunity Section, Laboratory of Host Defenses, NIAID, NIHCategory: Clinical Center Grand RoundsAired date: 01/21/2015 (Source: Videocast - All Events)
Source: Videocast - All Events - January 22, 2015 Category: Journals (General) Tags: Past Events Source Type: video
CC Grand Rounds: (1) Myelokathectic Immunodeficiency Disorders: Tales from the Clinic (2) Ulcerative Colitis: An Atypical Th2 Disorder Mediated by NKT Cells
For more information go to http://www.cc.nih.gov/about/news/grcurrent.htmlAir date: 1/21/2015 12:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - January 5, 2015 Category: Journals (General) Tags: Upcoming Events Source Type: video
How to Learn in "The Learning Healthcare System"
National Library of Medicine Informatics Lecture Series
The Institute of Medicine has argued for more than 20 years that we should view every patient interaction as an (uncontrolled) experiment, and learn from its outcome. Dr. Szolovits has been a participant in numerous collaborative projects, trying to apply this method to data about a broad range of patients suffering from conditions such as arthritis, cardiovascular disease, diabetes, inflammatory bowel disease, autism, depression. In this lecture, he will review some of the methodological challenges he has encountered and the hard-won lessons he has learned. These...
Source: Videocast - All Events - September 22, 2014 Category: Journals (General) Tags: Upcoming Events Source Type: video
