Elicio Therapeutics Announces FDA Clearance of IND application for ELI-002-- A Therapeutic Vaccine Targeting mutated KRAS Cancers
Phase I/II Clinical Trial to Be Initiated in First Quarter 2021 CAMBRIDGE, Mass., Feb. 23, 2021 -- (Healthcare Sales & Marketing Network) -- Elicio Therapeutics, a private biotechnology company developing a pipeline of potent immunotherapies based on i... Biopharmaceuticals, Oncology, FDA Elicio Therapeutics, Amphiphile, KRAS, pancreatic ductal adenocarcinoma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 23, 2021 Category: Pharmaceuticals Source Type: news

Cancer Death Rates Continue to Fall in Europe, Except For... Cancer Death Rates Continue to Fall in Europe, Except For...
Cancer death rates overall continue to fall in the EU, with the exception of pancreatic cancer in both sexes and lung cancer among women.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 23, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

What Is the #1 Cause of Pancreatic Cancer
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 23, 2021 Category: General Medicine Source Type: news

What Is the Cause of Pancreatic Cancer
What Is the #1 Cause of Pancreatic Cancer? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 23, 2021 Category: General Medicine Source Type: news

New insights on how inflammatory molecule contributes to skin and pancreatic cancers
(Massachusetts General Hospital) An immune molecule called interleukin-33 can act within a cell's nucleus to stimulate abnormal growth and division, ultimately resulting in cancer. Targeting interleukin-33 in the nucleus may help prevent certain cancers. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 22, 2021 Category: International Medicine & Public Health Source Type: news

Investment needed to bring down pancreatic cancer death rates in Europe
(European Society for Medical Oncology) Researchers have called on European policymakers to make adequate resources available to tackle pancreatic cancer, a disease that is almost invariably fatal and where little progress has been made over the past 40 years. The latest predictions for cancer deaths in the EU and UK for 2021, published in the leading cancer journal Annals of Oncology, show that pancreatic death rates are predicted to remain approximately stable for men, but continue to rise in women in most EU countries. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 21, 2021 Category: Cancer & Oncology Source Type: news

UCLA study finds combination therapy suppresses pancreatic tumor growth in mice
(University of California - Los Angeles Health Sciences) UCLA Jonsson Comprehensive Cancer Center researchers have uncovered a potential new way to target pancreatic tumors that express high intratumoral interferon signaling (IFN). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 18, 2021 Category: Cancer & Oncology Source Type: news

Raised Serum Amylase in COVID-19 Patients May Not Be Acute Pancreatitis Raised Serum Amylase in COVID-19 Patients May Not Be Acute Pancreatitis
A higher-than-normal serum amylase level in patients with COVID-19 does not necessarily indicate acute pancreatitis or clinically important pancreatic injury, as has been proposed in the literature, say clinicians in the UK.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - February 16, 2021 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Dopamine is key to the mystery of metabolic dysfunction in psychiatric patients
(University of Pittsburgh) Antipsychotic drugs not only block dopamine signaling in the brain but also in the pancreas, leading to uncontrolled production of blood glucose-regulating hormones, obesity and diabetes. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 15, 2021 Category: International Medicine & Public Health Source Type: news

Drug is promising against pancreatic and breast cancers
(Georgia State University) The drug is effective at treating pancreatic cancer and prolonging survival in mice, according to a study published in the journal Cellular and Molecular Gastroenterology and Hepatology. A second study, published in the Journal of Experimental Medicine, shows the drug is also effective against triple-negative breast cancer, a fast-growing and hard-to-treat type of breast cancer that carries a poor prognosis. Clinical trials are set to begin in 2021. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 9, 2021 Category: Cancer & Oncology Source Type: news

ATDC KEAPs NRF2 active
ATDC promotes pancreatic cancer progression and chemoresistance by disrupting KEAP1-mediated ubiquitylation of NRF2. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 9, 2021 Category: Science Authors: VanHook, A. M. Tags: STKE Editors ' Choice Source Type: news

COVID-19 Attacks the Pancreas COVID-19 Attacks the Pancreas
The new coronavirus directly targets the pancreas, infecting and damaging its insulin producing cells, according to a new study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 8, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Covid and cancer: 'A stranger helped me cope with my terminal illness'
Minna Heeraman's surgery for pancreatic cancer was delayed because of the coronavirus pandemic. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - February 7, 2021 Category: Consumer Health News Source Type: news

How Scientists Shot Down Cancer ’s ‘Death Star’
No drug could touch a quivering protein implicated in a variety of tumors. Then one chemist saw an opening. (Source: NYT Health)
Source: NYT Health - February 5, 2021 Category: Consumer Health News Authors: Gina Kolata Tags: Lung Cancer Pancreatic Cancer Colon and Colorectal Cancer Drugs (Pharmaceuticals) Smoking and Tobacco Lungs Genetics and Heredity Tumors Pancreas Clinical Trials Amgen Inc United States Source Type: news

Pancreatic cancer: What do your faeces smell like? Hidden warning sign found in your poo
PANCREATIC cancer symptoms are often non-specific and vague in the beginning. One of the first noticeable signs is the smell of your faeces. (Source: Daily Express - Health)
Source: Daily Express - Health - February 4, 2021 Category: Consumer Health News Source Type: news

New biomarker may predict which pancreatic cancer patients respond to CD40 immunotherapy
(University of Pennsylvania School of Medicine) Inflammation in the blood could serve as a new biomarker to help identify patients with advanced pancreatic cancer who won't respond to the immune-stimulating drugs known as CD40 agonists, suggests a new study from researchers in the Abramson Cancer Center of the University of Pennsylvania published inJCI Insight. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 4, 2021 Category: Cancer & Oncology Source Type: news

MSK scientists learn how genes and environment conspire in pancreatic cancer development
(Memorial Sloan Kettering Cancer Center) Both genes and environment are necessary to trigger pancreatic cancer development. A new study from Memorial Sloan Kettering researchers explains why. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 3, 2021 Category: Cancer & Oncology Source Type: news

Perioperative Chemo Feasible for Resectable Pancreatic Cancer
Phase 2 randomized trial revealed similar overall survival for two active regimens compared with adjuvant therapy (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 2, 2021 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Pharmacy, Radiology, Surgery, Journal, Source Type: news

Perioperative Chemo Feasible for Resectable Pancreatic Cancer
TUESDAY, Feb. 2, 2021 -- Perioperative chemotherapy for resectable pancreatic cancer is safe and effective, but it did not improve overall survival (OS) compared with historical data from trials of adjuvant therapy, according to a study published... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 2, 2021 Category: Pharmaceuticals Source Type: news

Nanoparticle drug delivery technique shows promise for treating pancreatic cancer
(Veterans Affairs Research Communications) Veterans Affairs researchers have designed a new way to deliver pancreatic cancer drugs that could make fighting the disease much easier. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 28, 2021 Category: International Medicine & Public Health Source Type: news

Mechanism for how pancreatic cancer evades immunotherapy elucidated
(Georgetown University Medical Center) Pancreatic cancer, one of the most lethal of all cancers, is capable of evading attacks by immune cells by changing its microenvironment so that the immune cells suppress, rather than support, an attack on the tumor. The scientists also found that that some of the mediators of this suppressive response, including a protein called STAT1, represent potential therapeutic targets that could be used to reverse this evasion and point to possible treatment opportunities. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 28, 2021 Category: Cancer & Oncology Source Type: news

UK Launch for Most Advanced'Artificial Pancreas', MiniMed 780G UK Launch for Most Advanced'Artificial Pancreas', MiniMed 780G
Medtronic launches latest MiniMed 780G hybrid closed-loop insulin delivery system in the UK.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 27, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

High Cost of Pancreatic Enzymes a Barrier for Patients With Cancer High Cost of Pancreatic Enzymes a Barrier for Patients With Cancer
These products are often essential for the treatment of pancreatic cancer, but out-of-pocket costs for a 30-day supply on Medicare can reach $1000 or more.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 26, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Researchers develop virus-based treatment platform to fight pancreatic cancer
(Queen Mary University of London) Researchers from Queen Mary University of London and Zhengzhou University have developed a powerful therapeutic platform that uses a modified virus for the treatment of pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 26, 2021 Category: Cancer & Oncology Source Type: news

Opioid Use May Contribute to Risk for Pancreatic Cancer
At the state level, opioid death rate at four years prior predicted the initial incidence of pancreatic cancer (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 22, 2021 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pharmacy, Anesthesiology & amp; Pain, Journal, Source Type: news

Opioid Use May Contribute to Risk for Pancreatic Cancer
FRIDAY, Jan. 22, 2021 -- Opioid use seems to contribute to the increasing incidence of pancreatic cancer (PC) in the United States, according to a study published online Jan. 6 in PLOS ONE. Usman Barlass, M.D., from Rush University Medical Center... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 22, 2021 Category: Pharmaceuticals Source Type: news

Novel target identified that could improve safety of therapy for pancreatic cancer
(Queen Mary University of London) Researchers from Queen Mary University of London, have identified a protein that may represent a novel therapeutic target for the treatment of pancreatic cancer. Using this protein as a target, the team successfully created a CAR T cell therapy - a type of immunotherapy - that killed pancreatic cancer cells in a pre-clinical model. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 22, 2021 Category: Cancer & Oncology Source Type: news

Pancreatic & #946; cell-derived exosomal miR-29 family enhances hepatic glucose output
(Nanjing University School of Life Sciences) In a new study published inJournal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreaticβ cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs). Thesesβ cell-derived exosomal miR-29s regulate glucose homeostasis through their manipulations on glucose output in liver. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 22, 2021 Category: International Medicine & Public Health Source Type: news

New Standard for Borderline Resectable Pancreatic Cancer New Standard for Borderline Resectable Pancreatic Cancer
Neoadjuvant mFOLFIRINOX was associated with favorable overall survival compared to historical data, but the addition of hypofractionated radiotherapy did not improve outcomes.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 20, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

New Standard for Borderline Resectable Pancreatic Cancer New Standard for Borderline Resectable Pancreatic Cancer
Neoadjuvant mFOLFIRINOX was associated with favorable overall survival compared to historical data, but the addition of hypofractionated radiotherapy did not improve outcomes.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 20, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Celebrity Deaths: Stars and Famous People We've Lost in 2021
Master illusionist Fischbacher has died of pancreatic cancer, about eight months after his partner, Roy Horn, passed away from COVID-19 complications. ... When Siegfried and Roy did a magic show on... (Source: AARP.org News)
Source: AARP.org News - January 15, 2021 Category: American Health Source Type: news

Siegfried Fischbacher of Siegfried and Roy dead at 81
He was reportedly terminally ill with pancreatic cancer and recently underwent an operation to remove a tumor (Source: Reuters: Health)
Source: Reuters: Health - January 14, 2021 Category: Consumer Health News Source Type: news

Is there a place for whole-body cancer screening?
A whole-body imaging cancer screening program could be an effective way to...Read more on AuntMinnie.comRelated Reading: PET/MRI, CT predict pancreatic cancer treatment response PET/MRI ups lesion detection by 15% for some cancers What's whole-body CT's place in trauma imaging? Unique PET/CT video shows real-time blood, cardiac motion Can FDG-PET/MRI replace biopsy in breast cancer cases? (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - January 12, 2021 Category: Radiology Source Type: news

Woman becomes first patient to have NHS operation that made her liver work like a pancreas
At Christmas 2019, for the first time in two years, Claire Aylott ate a solid meal. The problem was pancreatitis, a condition that affects more than 40,000 people in the UK each year. (Source: the Mail online | Health)
Source: the Mail online | Health - January 12, 2021 Category: Consumer Health News Source Type: news

Prognosis Stage 4 Pancreatic Cancer Survival Rate
How Long Do You Have to Live with Stage 4 Pancreatic Cancer? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 11, 2021 Category: General Medicine Source Type: news

Alex Trebek's final "Jeopardy!" episode ends with sentimental tribute
A video tribute to the host closed Friday's episode of the quiz show, the final one that Trebek taped before pancreatic cancer claimed... (Source: Reuters: Health)
Source: Reuters: Health - January 9, 2021 Category: Consumer Health News Source Type: news

The link between opioid medication and pancreatic cancer
(Rush University Medical Center) Using Center for Disease Control's national population health and cancer statistics datasets, Rush University Medical Center researchers determined that a state's opioid death rate significantly predicted the trend in the incidence of pancreatic cancer years later. This is the first study showing opioid use may be a risk factor contributing to the increasing incidence of pancreatic cancer (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 6, 2021 Category: Cancer & Oncology Source Type: news

The Lustgarten Foundation and the AACR establish two new career development awards
(American Association for Cancer Research) The Lustgarten Foundation and the American Association for Cancer Research (AACR) have established two new career development awards for early-career female and underrepresented pancreatic cancer researchers, representing a generous commitment of the Lustgarten Foundation of up to $1.8 million. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 6, 2021 Category: Cancer & Oncology Source Type: news

FDA Authorizes Marketing of EndoRotor System
TUESDAY, Dec. 29, 2020 -- The U.S. Food and Drug Administration granted marketing authorization to the EndoRotor System, which provides a minimally invasive way to resect and remove necrotic tissue for patients with walled-off pancreatic necrosis... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 29, 2020 Category: Pharmaceuticals Source Type: news

FDA Clears Device to Remove Dead Pancreatic Tissue FDA Clears Device to Remove Dead Pancreatic Tissue
The EndoRotor System (Interscope, Inc) facilitates resection and removal of necrotic tissue resulting from complications of acute pancreatitis.FDA Approvals (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - December 25, 2020 Category: Gastroenterology Tags: Gastroenterology News Alert Source Type: news

Interscope Announces FDA De Novo Marketing Authorization of the EndoRotor(R) System for Direct Endoscopic Necrosectomy (DEN)
The First and Only System Designed and Indicated for DEN now Available in the United States and Europe NORTHBRIDGE, Mass., Dec. 24, 2020 -- (Healthcare Sales & Marketing Network) -- Interscope, Inc. announced today the receipt of FDA de novo clearance ... Devices, Surgery, FDA Interscope, EndoRotor, Direct Endoscopic Necrosectomy, pancreatic necrosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - December 24, 2020 Category: Pharmaceuticals Source Type: news

Incidence and Survival Trends of Stage 1A Pancreatic Cancer Incidence and Survival Trends of Stage 1A Pancreatic Cancer
What have we learned in recent years about the incidence of stage 1 pancreatic cancer and the overall survival of these patients?Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 17, 2020 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Olathe biotech startup TVAX clears FDA hurdles for treatments to combat deadly cancers
In partnership with a California company, TVAX Biomedical Inc. developed an immunotherapy treatment for pancreatic cancer. (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - December 15, 2020 Category: Health Management Authors: Ellen Cagle Source Type: news

Olathe biotech startup TVAX clears FDA hurdles for treatments to combat deadly cancers
In partnership with a California company, TVAX Biomedical Inc. developed an immunotherapy treatment for pancreatic cancer. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 15, 2020 Category: Biotechnology Authors: Ellen Cagle Source Type: news

PET/MRI, CT predict pancreatic cancer treatment response
Metabolic metrics tracked on PET/MRI and morphologic metrics tracked on CT...Read more on AuntMinnie.comRelated Reading: AI can aid radiologists in detecting pancreatic cancer ASTRO updates guidance on pancreatic cancer USPSTF again dismisses pancreatic cancer screening Theranostic approach could aid pancreatic cancer patients Contrast US more accurately types pancreatic lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 15, 2020 Category: Radiology Source Type: news

MinIP reconstructions boost CT's COVID-19 performance
Minimum intensity projection (MinIP) reconstructions improve the accuracy of...Read more on AuntMinnie.comRelated Reading: PET/MRI, CT predict pancreatic cancer treatment response AI body analysis finds lung cancer survival risk factors Gaps in lung nodule follow-up linked to racial disparities CT effective for identifying body-concealed contraband CT radiomics characterizes complex cystic renal lesions (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 15, 2020 Category: Radiology Source Type: news

New combination therapy could help fight difficult-to-treat cancers with common mutations
(University of California - Los Angeles Health Sciences) UCLA scientists describe a new combination therapy that suppresses the MAPK pathway by holding cancer-driving proteins in a death grip. This combination of two small molecules has the potential to treat not only BRAF mutated melanoma but also additional aggressive subtypes of cancers, including melanoma, lung, pancreatic and colon cancers that harbor common mutations in cancer genes called RAS or NF1. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 14, 2020 Category: International Medicine & Public Health Source Type: news

Compound derived from thunder god vine could help pancreatic cancer patients
(The Translational Genomics Research Institute) The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 14, 2020 Category: Cancer & Oncology Source Type: news

PET/MRI, CT metrics assess pathologic response of pancreas cancer to neoadjuvant therapy
(American Roentgen Ray Society) According to an open-access Editor's Choice article in ARRS' American Journal of Roentgenology (AJR), post-neoadjuvant therapy (NAT) changes in metabolic metrics from PET/MRI and morphologic metrics from CT were associated with pathologic response and overall survival in patients with pancreatic ductal adenocarcinoma (PDA). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 9, 2020 Category: Cancer & Oncology Source Type: news

UK's unique national pancreas tissue bank opens for business
(Queen Mary University of London) The UK's national tissue bank for pancreatic diseases is open for applications from any UK-based researchers needing samples of blood, urine and saliva to aid their research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 9, 2020 Category: Cancer & Oncology Source Type: news