Hydromorphone-CR Exposure Ups Heart Infection Risk in PWID
FRIDAY, Jan. 31, 2020 -- Exposure to controlled-release hydromorphone, an opioid that can be abused through crushing and injection, is associated with an increased risk for infective endocarditis among people who inject drugs, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 31, 2020 Category: Pharmaceuticals Source Type: news

Should We Worry About Bicuspid Aortic Valve?
Discussion The aortic valve usually has 3 leaflets. In bicuspid aortic valve (BAV) there are 2 asymmetric leaflets with a fish-mouthed orifice between them which may not open fully. It occurs in about 0.5-2% of the population making it one of the most common congenital heart anomalies and the most common one in adults. Transmission is autosomal dominant yet males are more likely to have BAV, indicating potential reduced penetrance in females. “BAVs are different, however, in that the tissue pathology is not limited to the valves’ leaflets but extends from the left ventricular outflow tract to the ascending thor...
Source: PediatricEducation.org - January 27, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Controlled-release opioid may be leading to heart infections in persons who inject drugs
(Lawson Health Research Institute) A new study from ICES, Lawson Health Research Institute and Western University suggests that injection drug users prescribed controlled-release hydromorphone are three times more likely to develop endocarditis, a serious bacterial heart infection, when compared to those prescribed other opioids. The findings, published today in The Lancet Infectious Diseases, build on growing evidence that some controlled-release opioids may lead to higher risk of infectious disease among persons who inject drugs. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 22, 2020 Category: Infectious Diseases Source Type: news

Firefighter has open heart surgery after using a metal NAIL to get popcorn out of his teeth
Adam Martin, a 41-year-old father-of-three from Coverack in Cornwall, developed heart infection endocarditis after he used a pen lid, piece of wire and a metal nail to try and pick his teeth. (Source: the Mail online | Health)
Source: the Mail online | Health - January 6, 2020 Category: Consumer Health News Source Type: news

Rising burden of hospitalisations for infective endocarditis in US
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 1, 2020 Category: Drugs & Pharmacology Source Type: news

Knowledge and Compliance of Dentists' and Dental Students' With Respect to Relevant Guidelines for Prescribing Antibiotic Prophylaxis for the Prevention of Infective Endocarditis: A Systematic Review
ConclusionKnowledge levels of guidelines for antibiotic prophylaxis varied greatly depending on the study design, respondent characteristics, and time period factors. There is a lack of research published on compliance rates for dentists and dental students with respect to guidelines for the prevention of infective endocarditis. (Source: Dental Technology Blog)
Source: Dental Technology Blog - December 20, 2019 Category: Dentistry Source Type: news

Endocarditis After Transcatheter Aortic Valve Implantation Endocarditis After Transcatheter Aortic Valve Implantation
Infective endocarditis after TAVI is a potentially life-threatening complication. This commentary highlights the need for increased efforts to improve its prevention, diagnosis, and treatment.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2019 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Endocarditis After TAVR on Par With Surgery, Lethal for Both Endocarditis After TAVR on Par With Surgery, Lethal for Both
Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 6, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Stress Disorders Linked to Life-threatening Infections Stress Disorders Linked to Life-threatening Infections
PTSD or other stress-related conditions are tied to an increased risk of life-threatening infection, including sepsis, endocarditis, and meningitis, new research suggests.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - October 24, 2019 Category: Psychiatry Tags: Psychiatry News Source Type: news

Stress-related disorders linked to subsequent risk of severe infections
Risk of meningitis, sepsis and endocarditis rises following severe conditions triggered by a significant life event or trauma Related items fromOnMedica Bipolar disease risk four times higher with prenatal flu exposure Attitudes to mental health problems have improved Scheme to help depressed patients is rolled out nationwide Management support for depressed employees linked to fewer days off Mental health patients being sent long distances for treatment (Source: OnMedica Latest News)
Source: OnMedica Latest News - October 24, 2019 Category: UK Health Source Type: news

Substance Use Disorder Ups Risk for Death After IE Valve Surgery
TUESDAY, Oct. 22, 2019 -- Patients with infective endocarditis (IE) and substance use disorder (SUD) have a more than twofold risk for dying following valve surgery compared with patients without SUD, according to a study published online Oct. 16 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 22, 2019 Category: Pharmaceuticals Source Type: news

Public Outcomes Reporting Tied to Drop in Valve Replacements
MONDAY, Oct. 21, 2019 -- Initiating public reporting was associated with a significant decrease in valve surgery for all infective endocarditis (IE) cases, regardless of injection drug use (IDU) status, according to a study published Oct. 10 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 21, 2019 Category: Pharmaceuticals Source Type: news

A Blood Filter Fights Deadly Inflammatory Response
A new blood filtration technology may prove to be life-saving for patients whose normally healthy inflammatory response to injury or illness has gone into overdrive, resulting in fatally high levels of cytokines in their blood. In an interview with MD+DI, Dr. Phillip Chan, MD, PhD, CEO of CytoSorbents Corp., explained that inflammation, and the production of substances called cytokines that drive inflammation, are the body’s natural response to heal injury or infection. But sometimes, the inflammatory response is so severe in such conditions as sepsis and infection, burn injuries, trauma, pancreatitis, li...
Source: MDDI - October 9, 2019 Category: Medical Devices Authors: Susan Shepard Tags: Cardiovascular Source Type: news

2002 to 2016 Saw Rise in Drug Abuse-Linked Infective Endocarditis
WEDNESDAY, Sept. 18, 2019 -- The incidence of infective endocarditis (IE) associated with drug abuse (DA) increased from 2002 to 2016 in the United States, with increases seen in all regions, according to a study published online Sept. 18 in the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 18, 2019 Category: Pharmaceuticals Source Type: news

Valvular Heart Disease
series:Cardiovascular MedicineThis book provides up-to-date and user-friendly guidance on the evaluation, diagnosis, and treatment of heart and vascular disease. Chapters cover a broad range of issues related to valve disease, including rheumatic fever, aortic root dilatation, infective endocarditis, and heart disease in pregnancy. The physical examination of major valve lesions, imaging techniques, and choosing a balance ... (Source: Springer Medicine titles)
Source: Springer Medicine titles - August 31, 2019 Category: Databases & Libraries Tags: Cardiology Source Type: news

Infective Endocarditis Prevalence 26 Percent in Patients With E. faecalis
MONDAY, July 8, 2019 -- The prevalence of infective endocarditis (IE) is about 26 percent among patients with Enterococcus faecalis bacteremia, according to a study published in the July 16 issue of the Journal of the American College of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 8, 2019 Category: Pharmaceuticals Source Type: news

Simple Blood Draw Detects Dangerous Pathogens
Liquid biopsy has attracted a surge of companies that are trying to change the way cancer is detected and monitored. But the benefits of this new type of technology can - and should - seep into other disease categories. Redwood City, CA-based Karius, for example, is leveraging liquid biopsy technology to give doctors an upper hand on difficult-to-diagnose infectious diseases. New findings show the potential clinical utility of its the Karius Test to detect pathogens causing serious infections using a simple blood draw. This includes pathogens that are otherwise difficult to culture or identify witho...
Source: MDDI - June 26, 2019 Category: Medical Devices Authors: Amanda Pedersen Tags: IVD Source Type: news

Quick sepsis-related organ failure assessment score as a possible predictor for in-hospital adverse events in infective endocarditis.
Infective endocarditis (IE) can be life-threatening because of various associated adverse events. The quick Sepsis-related Organ Failure Assessment (qSOFA) score is a straightforward useful method for predicting in-hospital mortality in patients with suspected infections. However, few data exist regarding the clinical impact of the qSOFA score on predicting adverse events in IE during hospitalization. We studied the usefulness of qSOFA score for predicting in-hospital adverse events in patients with IE. These results showed that high qSOFA score was significantly associated with in-hospital adverse events in IE patients, a...
Source: Current Awareness Service for Health (CASH) - May 29, 2019 Category: Consumer Health News Source Type: news

AHA Abx Prophylaxis Guidelines Hit Moderate-Risk Target AHA Abx Prophylaxis Guidelines Hit Moderate-Risk Target
A Canadian analysis suggests the guidelines on antibiotic prophylaxis are having their intended effect, but also identified increasing rates of infective endocarditis it says are unrelated.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - May 10, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Caito Foods, LLC Voluntarily Recalls Fresh Cut Melon Product Because of Possible Health Risk
Caito Foods is voluntarily recalling fresh cut watermelon, fresh cut honeydew melon, fresh cut cantaloupe and fresh cut mixed fruit containing one of these melons, produced at the Caito Foods facility in Indianapolis because these products have the potential to be contaminated with Salmonella Carrau, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. In rare circumstances, infection with Salm...
Source: Food and Drug Administration - April 13, 2019 Category: Food Science Source Type: news

Experts call for strategies to address public health crisis of opioid, ID epidemics
(Infectious Diseases Society of America) Citing the spread of infections linked to rising rates of opioid use across the country including HIV, viral hepatitis, skin and soft tissue infections, bone and joint infections and endocarditis, an article published in the Journal of Infectious Diseases calls on the federal government to support coordinated and strengthened responses by infectious diseases and substance use specialists. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 4, 2019 Category: International Medicine & Public Health Source Type: news

POET: No Late Failure With Oral Antibiotic for Endocarditis POET: No Late Failure With Oral Antibiotic for Endocarditis
Longer-term follow-up of patients with left-sided infectious endocarditis shows no delayed issues with an early switch to oral from IV antibiotics.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 21, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Trial Sheds Light on Oral vs IV Antibiotics for Left-sided Endocarditis
(MedPage Today) -- But researchers caution that more research is needed before changing practice (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - March 18, 2019 Category: Infectious Diseases Source Type: news

CorMatrix launches FDA IDE Cor Tricuspid ECM cardiac valve trial
CorMatrix Cardiovascular said today that it launched a trial of its Cor Tricuspid ECM cardiac valve intended for treating adults with endocarditis and pediatric patients with congenital heart valve disease, adding that the first patient in the trial has already been treated. The first procedure in the trial took place at the Francicscan Health Heart Center by a team led by Dr. Marc Gerdisch, Atlanta-based CorMatrix said. The patient, who was suffering from endocarditis, has returned home and is recovering well, the company added. “This first FDA study enrollment is a substantial step toward patients avoiding syn...
Source: Mass Device - February 21, 2019 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Clinical Trials Featured Replacement Heart Valves CorMatrix Cardiovascular Inc. Source Type: news

Knowledge and compliance of dentists ’ and dental students’ with respect to relevant guidelines for prescribing antibiotic prophylaxis for the prevention of infective endocarditis: A systematic review.
ConclusionKnowledge levels of guidelines for antibiotic prophylaxis varied greatly depending on study design, respondent characteristics and time period factors. There is a lack of research published on compliance rates for dentists and dental students with respect to guidelines for the prevention of infective endocarditis. (Source: Dental Technology Blog)
Source: Dental Technology Blog - February 18, 2019 Category: Dentistry Source Type: news

Safety board OKs continuation of CytoSorbents endocarditis trial
CytoSorbents (OTC:CTSO) said this week it the Data Safety Monitoring Board of its REMOVE trial gave the company the green light to continue the study after analyzing data from the first 50 patients. The German gov’t-funded randomized, controlled, multi-center 250-patient REMOVE trial, which was launched in late 2017, looked to explore the safety and efficacy of intraoperative CytoSorb in patients with dangerous bacterial heart valve infections during valve replacement surgeries and cardiopulmonary bypass procedures, the Monmouth, N.J.-based company said. The study’s goal is to demonstrate improved hemodyna...
Source: Mass Device - February 6, 2019 Category: Medical Devices Authors: Fink Densford Tags: Blood Management Clinical Trials Regulatory/Compliance CytoSorbents Corp. Source Type: news

Increasing Stroke Tied to Injectable Opioids, Endocarditis Increasing Stroke Tied to Injectable Opioids, Endocarditis
The dramatic increase over the last decade in US hospitalizations for stroke from injectable drug-related infective endocarditis coincides with the surge in opioid misuse, new research suggests.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 31, 2019 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Infective Endocarditis Related to Injection Drug Use Rising
WEDNESDAY, Jan. 30, 2019 -- The risk for infective endocarditis related to injection drug use increased from 2006 to 2015, according to a study published online Jan. 28 in CMAJ, the journal of the Canadian Medical Association. Matthew A. Weir, M.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 30, 2019 Category: Pharmaceuticals Source Type: news

Opioid epidemic is fueling a rise in STROKES: Rate has soared in 20 years
When users inject heroin, traces of bacteria can enter their bloodstream, which can reach their heart causing endocarditis. New data show strokes from opioid-related endocarditis has rocketed. (Source: the Mail online | Health)
Source: the Mail online | Health - January 30, 2019 Category: Consumer Health News Source Type: news

Vaccination with Streptococcus mitis could protect against virulent sibling, Streptococcus pneumonia
(American Society for Microbiology) Vaccinating laboratory mice with Streptococcus mitis bacteria prevents their virulent sibling, Streptococcus pneumoniae from infecting the mice. The research suggests that vaccination of humans with live S. mitis might offer protection from some of the many serotypes of S. pneumoniae that vaccines currently do not exist for. This pathogen is one of the most common causes of severe pneumonia, and can also cause meningitis, bloodstream and sinus infections, endocarditis, and middle ear infections in young children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news

Opioid injecting linked to substantial rise in bacterial heart infections
(Canadian Medical Association Journal) A study of people who inject drugs found a significant increase in the risk of infective endocarditis, a serious infection of the lining of the heart, possibly linked to increasing use of the opioid hydromorphone. The study is published in CMAJ. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 28, 2019 Category: International Medicine & Public Health Source Type: news

Injection of opioids linked to significant increase in bacterial heart infections
(Lawson Health Research Institute) In a new study from ICES, Lawson Health Research Institute and Western University, researchers discovered a significant rise in the risk of infective endocarditis, a serious heart infection, among Ontarians who inject drugs. When examining opioid prescriptions in the province, the research team discovered the increased risk of infective endocarditis may be related to the growing use of a specific opioid, hydromorphone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 28, 2019 Category: Infectious Diseases Source Type: news

CorMatrix wins FDA IDE approval for Cor Tricuspid ECM cardiac valve trial
CorMatrix Cardiovascular said today that it won FDA investigational device exemption approval to launch an early feasibility study of its Cor Tricuspid ECM cardiac valve intended for treating adults with endocarditis and pediatric patients with congenital heart valve disease. The Atlanta-based company touts its Cor Tricuspid valve as the first cardiac valve of its kind to be composed of an extracellular matrix, and said that its CorMatrix ECM has been used in more than 220,000 cardiac implants to date. “This important step for our patients and CorMatrix to create a valve that will mimic in all respects a normal valve...
Source: Mass Device - January 24, 2019 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Clinical Trials Food & Drug Administration (FDA) Regulatory/Compliance Replacement Heart Valves CorMatrix Cardiovascular Inc. Source Type: news

2018 Landmark Infectious Diseases Trials, in Graphic Form
(MedPage Today) -- New flu antiviral, oral abx for stable endocarditis among standouts (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 6, 2019 Category: Infectious Diseases Source Type: news

Drug Use-Associated Infective Endocarditis Up 2007 to 2017
WEDNESDAY, Dec. 26, 2018 -- From 2007 to 2017 there was an increase in drug-use associated infective endocarditis (DUA-IE) hospitalizations and valve surgeries, according to a study published online Dec. 4 in the Annals of Internal Medicine. Asher... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 26, 2018 Category: Pharmaceuticals Source Type: news

Infective Endocarditis: Spike in N.C. Linked to Opioid Epidemic (CME/CE)
(MedPage Today) --'Alarming'increase prompts call to improve the related'cascade of care'(Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 5, 2018 Category: American Health Source Type: news

Infective Endocarditis: A New Consequence of the Opioid Epidemic Infective Endocarditis: A New Consequence of the Opioid Epidemic
A'staggering increase'in the occurrence of drug use-associated infective endocarditis is reported in a new study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Opioid Crisis Linked to Spike in Infective Endocarditis
(MedPage Today) -- Ten-fold rise in one state prompts urgent call for action (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 3, 2018 Category: Psychiatry Source Type: news

Cardiac surgery and addictions counselling linked to significantly reduced mortality in injection drug users with heart valve infection, study finds
(Lawson Health Research Institute) In a new study, researchers at Lawson Health Research Institute and Western University showed that both surgery and in-hospital addictions counselling are linked to significantly reduced mortality in injection drug users with first-episode endocarditis. Surgery was associated with a 56 per cent reduction in mortality, while in-hospital addictions counselling was associated with a 72 per cent reduction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 21, 2018 Category: Infectious Diseases Source Type: news

Opioids: Epidemic of Our Time and Impact on Infectious Disease
Source: National Institutes of Health (NIH). Published: 11/13/2018. This one-hour, five-minute presentation, the 2018 Kinyoun Lecture at the National Institutes of Health, explores the impacts of the unprecedented use of opioids in the United States on the management of infectious diseases. While overdose remains the leading cause of death among people who use opioids, this population is also disproportionately affected by viral hepatitis, bacterial endocarditis, HIV, and other infections associated with sharing and reusing needles to inject drugs and other behaviors linked to illicit drug use. (Video or Multimedia) (Sour...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - November 17, 2018 Category: International Medicine & Public Health Source Type: news

Curbs on Predental Antibiotics Maybe Went Too Far in Practice Curbs on Predental Antibiotics Maybe Went Too Far in Practice
Calls in 2007 to cut back on antibiotic prophylaxis didn't apply to all patients, but clinical practice responded by pulling back in everybody. For at least one group, endocarditis soared.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news

AHA: After 2007 Recs, Increase Seen in Infective Endocarditis
TUESDAY, Nov. 6, 2018 -- Following the 2007 American Heart Association (AHA) update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE), there has been a decrease in AP and an increase in IE incidence for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 6, 2018 Category: Pharmaceuticals Source Type: news

NICE should change antibiotic guidelines for dental patients -- study shows
(University of Sheffield) New research has revealed the impact a change in US guidelines had on the prescribing of antibiotic prophylaxis (AP) to prevent a life-threatening heart condition infective endocarditis (IE) in patients before undergoing invasive dental treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 5, 2018 Category: International Medicine & Public Health Source Type: news

Oral Antibiotics for Infective Endocarditis: Time to Switch? Oral Antibiotics for Infective Endocarditis: Time to Switch?
The standard of care for endocarditis for many years has been IV antibiotics, even though many patients don't complete the full treatment. Would oral antibiotics work just as well?Medscape Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 31, 2018 Category: Consumer Health News Tags: Infectious Diseases Commentary Source Type: news

LivaNova updates on 3T Heater-Cooler infection prevention corrections
LivaNova (NSDQ:LIVN) this week updated customers on efforts to correct issues with its 3T Heater-Cooler related to patient infections, providing instructions to monitor hydrogen peroxide concentration and information on a design upgrade. In a medical device correction letter dated October 18, the company sent instructions for monitoring hydrogen peroxide concentration to limit microbial growth, enhancing previous instructions, and informing users of a new vacuum canister and internal sealing design intended to “further mitigate” the risk of airborne transmission on non-tuberculosis mycobacterium. Last Sept...
Source: Mass Device - October 22, 2018 Category: Medical Devices Authors: Fink Densford Tags: Cardiovascular Featured Surgical LivaNova Source Type: news

N. Carolina Sees Alarming Spike in Heart Infections Among Opioid Users
WEDNESDAY, Oct. 17, 2018 -- Adding to growing alarm about America's opioid crisis, cases of a potentially deadly heart infection have jumped 10-fold among North Carolina's injection drug users, new research shows. The infection is endocarditis,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 16, 2018 Category: General Medicine Source Type: news

Wearable Woes; Mini-Pacer for Mice; Infective Endocarditis Test
(MedPage Today) -- Recent developments of interest in cardiovascular medicine (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 15, 2018 Category: Cardiology Source Type: news

The Speed of Sound: Ultrasound's Immediate Answers for Diagnosing Endocarditis
No abstract available (Source: Emergency Medicine News)
Source: Emergency Medicine News - October 1, 2018 Category: Emergency Medicine Tags: The Speed of Sound Source Type: news