Vaccination with Streptococcus mitis could protect against virulent sibling, Streptococcus pneumonia
(American Society for Microbiology) Vaccinating laboratory mice with Streptococcus mitis bacteria prevents their virulent sibling, Streptococcus pneumoniae from infecting the mice. The research suggests that vaccination of humans with live S. mitis might offer protection from some of the many serotypes of S. pneumoniae that vaccines currently do not exist for. This pathogen is one of the most common causes of severe pneumonia, and can also cause meningitis, bloodstream and sinus infections, endocarditis, and middle ear infections in young children. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news
Injection of opioids linked to significant increase in bacterial heart infections
(Lawson Health Research Institute) In a new study from ICES, Lawson Health Research Institute and Western University, researchers discovered a significant rise in the risk of infective endocarditis, a serious heart infection, among Ontarians who inject drugs. When examining opioid prescriptions in the province, the research team discovered the increased risk of infective endocarditis may be related to the growing use of a specific opioid, hydromorphone. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 28, 2019 Category: Infectious Diseases Source Type: news
Opioid injecting linked to substantial rise in bacterial heart infections
(Canadian Medical Association Journal) A study of people who inject drugs found a significant increase in the risk of infective endocarditis, a serious infection of the lining of the heart, possibly linked to increasing use of the opioid hydromorphone. The study is published in CMAJ. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 28, 2019 Category: International Medicine & Public Health Source Type: news
CorMatrix wins FDA IDE approval for Cor Tricuspid ECM cardiac valve trial
CorMatrix Cardiovascular said today that it won FDA investigational device exemption approval to launch an early feasibility study of its Cor Tricuspid ECM cardiac valve intended for treating adults with endocarditis and pediatric patients with congenital heart valve disease.
The Atlanta-based company touts its Cor Tricuspid valve as the first cardiac valve of its kind to be composed of an extracellular matrix, and said that its CorMatrix ECM has been used in more than 220,000 cardiac implants to date.
“This important step for our patients and CorMatrix to create a valve that will mimic in all respects a normal valve...
Source: Mass Device - January 24, 2019 Category: Medical Devices Authors: Fink Densford Tags: Cardiac Implants Cardiovascular Clinical Trials Food & Drug Administration (FDA) Regulatory/Compliance Replacement Heart Valves CorMatrix Cardiovascular Inc. Source Type: news
2018 Landmark Infectious Diseases Trials, in Graphic Form
(MedPage Today) -- New flu antiviral, oral abx for stable endocarditis among standouts (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 6, 2019 Category: Infectious Diseases Source Type: news
Drug Use-Associated Infective Endocarditis Up 2007 to 2017
WEDNESDAY, Dec. 26, 2018 -- From 2007 to 2017 there was an increase in drug-use associated infective endocarditis (DUA-IE) hospitalizations and valve surgeries, according to a study published online Dec. 4 in the Annals of Internal Medicine.
Asher... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 26, 2018 Category: Pharmaceuticals Source Type: news
Infective Endocarditis: Spike in N.C. Linked to Opioid Epidemic (CME/CE)
(MedPage Today) -- ' Alarming ' increase prompts call to improve the related ' cascade of care ' (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - December 5, 2018 Category: American Health Source Type: news
Infective Endocarditis: A New Consequence of the Opioid Epidemic Infective Endocarditis: A New Consequence of the Opioid Epidemic
A ' staggering increase ' in the occurrence of drug use-associated infective endocarditis is reported in a new study.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Opioid Crisis Linked to Spike in Infective Endocarditis
(MedPage Today) -- Ten-fold rise in one state prompts urgent call for action (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 3, 2018 Category: Psychiatry Source Type: news
Cardiac surgery and addictions counselling linked to significantly reduced mortality in injection drug users with heart valve infection, study finds
(Lawson Health Research Institute) In a new study, researchers at Lawson Health Research Institute and Western University showed that both surgery and in-hospital addictions counselling are linked to significantly reduced mortality in injection drug users with first-episode endocarditis. Surgery was associated with a 56 per cent reduction in mortality, while in-hospital addictions counselling was associated with a 72 per cent reduction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 21, 2018 Category: Infectious Diseases Source Type: news
Opioids: Epidemic of Our Time and Impact on Infectious Disease
Source: National Institutes of Health (NIH). Published: 11/13/2018.
This one-hour, five-minute presentation, the 2018 Kinyoun Lecture at the National Institutes of Health, explores the impacts of the unprecedented use of opioids in the United States on the management of infectious diseases. While overdose remains the leading cause of death among people who use opioids, this population is also disproportionately affected by viral hepatitis, bacterial endocarditis, HIV, and other infections associated with sharing and reusing needles to inject drugs and other behaviors linked to illicit drug use.
(Video or Multimedia) (Sour...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - November 17, 2018 Category: International Medicine & Public Health Source Type: news
Curbs on Predental Antibiotics Maybe Went Too Far in Practice Curbs on Predental Antibiotics Maybe Went Too Far in Practice
Calls in 2007 to cut back on antibiotic prophylaxis didn ' t apply to all patients, but clinical practice responded by pulling back in everybody. For at least one group, endocarditis soared.Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 9, 2018 Category: Consumer Health News Tags: Cardiology News Source Type: news
AHA: After 2007 Recs, Increase Seen in Infective Endocarditis
TUESDAY, Nov. 6, 2018 -- Following the 2007 American Heart Association (AHA) update of recommendations for antibiotic prophylaxis (AP) to prevent infective endocarditis (IE), there has been a decrease in AP and an increase in IE incidence for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 6, 2018 Category: Pharmaceuticals Source Type: news
NICE should change antibiotic guidelines for dental patients -- study shows
(University of Sheffield) New research has revealed the impact a change in US guidelines had on the prescribing of antibiotic prophylaxis (AP) to prevent a life-threatening heart condition infective endocarditis (IE) in patients before undergoing invasive dental treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 5, 2018 Category: International Medicine & Public Health Source Type: news
