Opioids: Epidemic of Our Time and Impact on Infectious Disease

Source: National Institutes of Health (NIH). Published: 11/13/2018. This one-hour, five-minute presentation, the 2018 Kinyoun Lecture at the National Institutes of Health, explores the impacts of the unprecedented use of opioids in the United States on the management of infectious diseases. While overdose remains the leading cause of death among people who use opioids, this population is also disproportionately affected by viral hepatitis, bacterial endocarditis, HIV, and other infections associated with sharing and reusing needles to inject drugs and other behaviors linked to illicit drug use. (Video or Multimedia)
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Source: Behavioural Neurology - Category: Neurology Authors: Tags: Behav Neurol Source Type: research
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Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Abstract More than 750,000 persons in the United States inject opioids, methamphetamine, cocaine, or ketamine, and that number is increasing because of the current opioid epidemic. Persons who inject drugs (PWID) are at higher risk of infectious and noninfectious skin, pulmonary, cardiac, neurologic, and other causes of morbidity and mortality. Nonjudgmental inquiries about current drug use can uncover information about readiness for addiction treatment and identify modifiable risk factors for complications of injection drug use. All PWID should be screened for human immunodeficiency virus infection, latent tuberc...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Robert R. Redfield, M.D., director of the Centers for Disease Control and Prevention (CDC), will deliver the 2018 Joseph J. Kinyoun Memorial Lecture on the intersection between the national opioid crisis and the management of infectious diseases. Titled, “ Opioids: Epidemic of Our Time and Impact on Infectious Disease, ” Dr. Redfield ’ s talk will explore the impacts of the unprecedented use of opioids in the United States on the management of infectious diseases. While overdose remains the leading cause of death among people who use opioids, this population is also disproportionately affected by viral he...
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Abstract In the United States, age-adjusted opioid overdose death rates increased by>200% during 1999-2015, and heroin overdose death rates increased nearly 300% during 2011-2015 (1). During 2011-2013, the rate of heroin use within the past year among U.S. residents aged ≥12 years increased 62.5% overall and 114.3% among non-Hispanic whites, compared with 2002-2004 (2). Increases in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) infections related to increases in injection drug use have been recently highlighted (3,4); likewise, invasive bacterial infections, including endocarditis, osteomyel...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Abstract Opioid dependence and overdose have increased to epidemic levels in the United States. The 2014 National Survey on Drug Use and Health estimated that 4.3 million persons were nonmedical users of prescription pain relievers (1). These users are 40 times more likely than the general population to use heroin or other injection drugs (2). Furthermore, CDC estimated a near quadrupling of heroin-related overdose deaths during 2002-2014 (3). Although overdose contributes most to drug-associated mortality, infectious complications of intravenous drug use constitute a major cause of morbidity leading to hospitaliz...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
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