In Rare Cases, Drug-Resistant'Superbugs' Can Pass Between People & Their Pets
MONDAY, March 20, 2023 -- In more bad news about antibiotic resistance, new research suggests that people and their pets may be able to transmit multidrug-resistant germs to each other.
Still, cases of cross-transmission are rare and it ' s not clear... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 20, 2023 Category: General Medicine Source Type: news
Sepsis and antibiotics: When should we deploy a parachute?
In sepsis and septic shock, guidelines recommend administering antimicrobial therapy within the first hour following diagnosis. This recommendation is based on observational studies suggesting that early antimicrobial therapy was associated with improved outcomes. Consequently, physicians working at the front line are under pressure to decide in a short time the need for antibiotics in patients in whom the diagnosis of sepsis remains uncertain. On the other hand, overuse of antibiotics is associated with emergence of multidrug resistant bacteria, which constitutes worldwide a major health issue. Physicians at the front lin...
Source: Current Awareness Service for Health (CASH) - March 14, 2023 Category: Consumer Health News Source Type: news
Sutezolid With 3-Drug Combo Appears Safe and Effective in Multidrug-Resistant TB
(MedPage Today) -- SEATTLE -- Adding the oxazolidinone antibiotic sutezolid to a three-drug combination appeared to be safe and effective for people with multidrug-resistant tuberculosis (TB), according to a dose-finding phase II study.
Across... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - February 21, 2023 Category: Infectious Diseases Source Type: news
The impact of bedside wipes in multi-patient rooms: a prospective, crossover trial evaluating infections and survival
Background: Multidrug resistant organisms (MDRO) are prevalent on high-touch surfaces in multi-patient rooms. We quantified the impact of hanging single-use cleaning/disinfecting wipes next to each bed. Pre-specified outcomes were: 1) hospital-acquired infections (HAI), 2) cleaning frequency, 3) MDRO room contamination, 4) new MDRO acquisitions, and 5) mortality. Methods: Clustered randomised crossover trial at Shamir Medical Center, Israel (10/2016-01/2018). Clusters were randomly assigned to use for cleaning either single-use quaternary ammonium wipes (Clinell ® ) or standard practices (reusable cloths and buckets with ...
Source: Current Awareness Service for Health (CASH) - February 7, 2023 Category: Consumer Health News Source Type: news
Healthcare workers' experiences of caring for patients colonized with carbapenemase-producing Enterobacterales (CPE) in an acute hospital settingA scoping review
In conclusion, healthcare workers have negative associations when it comes to caring for patients with CPE. Very little research has been conducted in the area and there is an opportunity to further explore the experience of healthcare workers caring for patients with CPE to identify opportunities for improvement and support of staff. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 3, 2023 Category: Consumer Health News Source Type: news
Incidence of infection with multidrug-resistant Gram-negative bacteria and vancomycin-resistant enterococci in carriers: a systematic review and meta-regression analysis
Review of 40 studies (n=14,049) found cumulative incidence of infection was substantial, with the highest risk for patients colonised with carbapenem-resistant Gram-negative bacteria (19%; p (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 1, 2023 Category: Consumer Health News Source Type: news
Plant toxin hailed as ‘new weapon’ in antibiotic war against bacteria
Scientists say albicidin has allowed them to take a giant step forward to creating a powerful new range of antibacterial drugsScientists have discovered a plant toxin whose unique method of dispatching bacteria could be used to create a powerful new range of antibiotics. The prospect of developing new antibacterial drugs this way has been hailed by doctors, who have been warning for many years that the steady rise of multidrug-resistant pathogens such asE coli now present a dangerous threat to healthcare across the planet.The new antibiotic – albicidin – attacks bacteria in a completely different way to existing drugs,...
Source: Guardian Unlimited Science - January 29, 2023 Category: Science Authors: Robin McKie Science Editor Tags: Antibiotics Medical research Science Society E coli UK news Microbiology Source Type: news
Africa: Groundbreaking MSF Trial Finds Better Treatment for People With Drug-Resistant Tuberculosis
[MSF] A new all-oral, six-month treatment regimen is safer and more effective at treating multidrug-resistant tuberculosis (MDR-TB) than the current options for people with drug-resistant TB (DR-TB), according to the results of an MSF study published in the New England Journal of Medicine today. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - December 22, 2022 Category: African Health Source Type: news
Researchers work on developing antibiotics for drug-resistant bacteria
Researchers at Hokkaido University are working on the development of antibiotics against multidrug-resistant bacteria, according to new research published in the journal Nature Communications. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 20, 2022 Category: Consumer Health News Source Type: news
Multidrug-Resistant Gram-Negative Infections Now Treatable Multidrug-Resistant Gram-Negative Infections Now Treatable
Some multidrug-resistant gram-negative infections are resistant to nearly all antibiotics, and the remaining few treatment options can cause serious complications.Medscape Medical News (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - December 9, 2022 Category: Intensive Care Tags: Infectious Diseases News Source Type: news
Novel Agents for Drug-Resistant Gram-Negative Infections Novel Agents for Drug-Resistant Gram-Negative Infections
Learn more about the newer options currently in development for the treatment of multidrug-resistant gram-negative infections.Current Opinion in Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 6, 2022 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
International Spread of Multidrug-Resistant Rhodococcus equi International Spread of Multidrug-Resistant Rhodococcus equi
The pathogen Rhodococcus equi has been spreading among horse farms in the United States, but now may have also spread to other countries.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 5, 2022 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news
Study Affirms Shorter Regimens for Drug-Resistant Tuberculosis Study Affirms Shorter Regimens for Drug-Resistant Tuberculosis
Two short-course bedaquiline-containing regimens are promising treatment options for multidrug-resistant tuberculosis.Medscape Medical News (Source: Medscape Infectious Diseases Headlines)
Source: Medscape Infectious Diseases Headlines - November 17, 2022 Category: Infectious Diseases Tags: Infectious Diseases News Source Type: news
Johnson & Johnson Rises to #2 in Ranking of Companies ’ Efforts to Expand Access to Medicines Worldwide
Everyone should have the opportunity to lead a healthy life. This requires that we advance equitable access to healthcare and address some of the world’s most devastating and neglected diseases.We are proud that Johnson & Johnson’s actions to expand access to our medicines and focus on addressing diseases that disproportionately impact people in lower- and middle-income countries has made us the 2nd-ranked company globally in the 2022 Access to Medicine Index.Our industry-leading performance marks an improvement, up from 3rd in 2021, and is the sixth consecutive time we are featured as a top three performer by the ...
Source: Johnson and Johnson - November 15, 2022 Category: Pharmaceuticals Source Type: news
Antibiotic treatment in patients with sepsis: a narrative review
Sepsis is a medical emergency and life-threatening condition due to a dysregulated host response to infection, with unacceptably high morbidity and mortality. Similar to acute myocardial infarction or cerebral vascular accident, sepsis is a severe and continuous time-dependent condition. Thus, in the case of sepsis, early and adequate administration of antimicrobials must be a priority, ideally within the first hour of diagnosis, simultaneously with organ support.As a consequence of the emergence of multidrug-resistant pathogens, the choice of antimicrobials should be performed according to the local pathogen patterns of r...
Source: Current Awareness Service for Health (CASH) - September 9, 2022 Category: Consumer Health News Source Type: news