Fight Aging! Newsletter, February 14th 2022

In conclusion, this first examination of the effects of age and the ageing process on the small intestinal microbiome demonstrates that the duodenal microbiome changes with increasing age, with significant decreases in duodenal microbial diversity due to increased prevalence of phylum Proteobacteria, particularly coliforms and anaerobic taxa. Given the key roles of small intestinal microbes in nutrient absorption and host metabolism, these changes may be clinically relevant for human health during the ageing process. Naked Mole Rats Exhibit Minimal Cardiac Aging https://www.fightaging.org/archives/2022/02/naked-mole-rats-exhibit-minimal-cardiac-aging/ Naked mole rats exhibit negligible senescence, meaning that that individuals show a minimal functional decline as a result of aging until very late life. They exhibit a very low incidence of cancer. They are one of the most studied species in the context of the comparative biology of aging, the search for longevity assurance mechanisms in unusually long-lived species that might become the basis for therapies to treat aging in humans. That naked mole rats are mammals gives the hope that any discoveries are more likely to be relevant to our species than is the case for investigations of lower animals, such as the work on exceptional regeneration in salamanders or zebrafish. In today's open access paper, the authors discuss heart function in aging naked mole rats. There is little speculation on mechanisms...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs