Science Saturday: Finding the right drug, dose for cancer therapy through pharmacogenomics
Each year, nearly 300,000 patients receive the lifesaving chemotherapy 5-fluorouracil (5-FU) to treat many types of cancer, including colorectal, breast, bowel, skin, pancreatic, and esophageal cancer. While it can be an effective treatment, it doesn?t work for everyone. In fact, up to 30 percent of those who receive the standard dose can have serious, life-threatening [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - December 8, 2018 Category: Databases & Libraries Source Type: news

PET tracers help guide breast cancer therapies
PET imaging tracers that track breast cancer enzymes could help guide treatment...Read more on AuntMinnie.comRelated Reading: SNMMI: Fluciclovine-PET changes prostate treatment Mammi-PET finds tiny breast lesions -- but could improve Fused MRI and PET improve specificity of breast MRI PEM performs well against breast MRI, whole-body PET NCPIC to provide PET breast scans for uninsured (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 7, 2018 Category: Radiology Source Type: news

The Future Of Cancer Care: A 50 Minute Discussion At Forbes
The future of cancer therapy, an analysis of how Immunotherapy has improved oncology outcomes for patients. This year's Forbes Summit highlighted both the difficulties, advancements and needs of the cancer care community in order to find the " cure " for cancer. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - December 5, 2018 Category: Pharmaceuticals Authors: Steve Brozak, Contributor Tags: NYSE:MRK NASDAQ:LOXO NASDAQ:ALLO Source Type: news

$5.1B deal: GSK buying ovarian cancer drug developer
In a major move to boost its oncology product pipeline, GlaxoSmithKline entered into a definitive agreement Monday to acquire Boston-area biopharmaceutical company Tesaro for $5.1 billion. Tesaro (NASDAQ: TSRO) of Waltham, Mass., markets the ovarian cancer therapy Zejula, which is approved in the United States and Europe. The company is also conducting clinical trials that if successful could lead to an expanded use of the drug, as a monotherapy and in combination with other ovaria n cancer treatments. “The… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - December 4, 2018 Category: Biotechnology Authors: John George Source Type: news

Oral drug for blood clot treatment safe for cancer patients, study says
A popular oral medication used to treat blood clots is safe and effective for patients going through cancer therapy, a study says. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 3, 2018 Category: Consumer Health News Source Type: news

Dutch firm argenx, J & J affiliate to collaborate on cancer therapy
Netherlands-based biopharmaceutical company argenx SE said it signed a deal with Cilag GmbH International, an affiliate of Johnson& Johnson's Janssen Pharmaceutical Companies unit, to develop its Cusatuzumab drug in certain types of cancer. (Source: Reuters: Health)
Source: Reuters: Health - December 3, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Larotrectinib: Targeting DNA in cancer therapy
(Children's Hospital Los Angeles) FDA grants accelerated approval for Vitrakvi ® (larotrectinib) for the treatment of solid tumors. This is marks the second FDA-approved drug for cancers based on their genetic makeup as opposed to location in the body. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 3, 2018 Category: Cancer & Oncology Source Type: news

Mayo researchers say oral apixaban safe and effective for treating blood clots in cancer patients
(Mayo Clinic) Mayo Clinic researchers have found that an oral drug, apixaban, used to treat blood clots in patients undergoing cancer therapy, is safe and effective. The drug was associated with fewer major bleeding events and fewer recurrent blood clots, compared to low-molecular- weight heparin. Their findings were presented at the annual meeting of the American Society of Hematology by Robert McBane II M.D., a Mayo Clinic cardiologist. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 3, 2018 Category: International Medicine & Public Health Source Type: news

Mayo researchers say oral apixaban safe and effective for treating blood clots in cancer patients
SAN DIEGO ??Mayo Clinic researchers have found that an oral drug, apixaban, used to treat blood clots in patients undergoing cancer therapy, is safe and effective. The drug was associated with fewer major bleeding events and fewer recurrent blood clots, compared to low-molecular- weight heparin. Their findings were presented at the annual meeting of the [...] (Source: Mayo Clinic Minnesota News)
Source: Mayo Clinic Minnesota News - December 3, 2018 Category: Hospital Management Source Type: news

High-contrast imaging for cancer therapy with protons
(Helmholtz-Zentrum Dresden-Rossendorf) Medical physicist Dr. Aswin Hoffmann and his team from the Institute of Radiooncology -- OncoRay at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) are the first researchers worldwide to combine magnetic resonance imaging with a proton beam, thus demonstrating that in principle, this commonly used imaging method can indeed work with particle beam cancer treatments. This opens up new opportunities for targeted, healthy tissue-sparing cancer therapy. The researchers published their results in the journal Physics in Medicine and Biology. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 29, 2018 Category: Cancer & Oncology Source Type: news

UCLA research suggests widely used breast cancer therapy doesn ’t cause cognitive decline
UCLA researchers have found that commonly used hormone therapies for women diagnosed with breast cancer do not appear to cause significant cognitive dysfunction following the treatment.Endocrine therapy has become an essential part of treatment for the many women diagnosed with hormone-receptor positive breast cancer, in which hormones, such as estrogen, promote cancer growth. The endocrine treatment helps lower the recurrence and reduce the risk of death from breast cancer by interfering with how a woman ’s own hormones can continue to support the growth of dormant cancer cells. Yet, there has been limited evidence ...
Source: UCLA Newsroom: Health Sciences - November 28, 2018 Category: Universities & Medical Training Source Type: news

Correcting Patients' Understanding of Alternative Cancer Therapies Correcting Patients' Understanding of Alternative Cancer Therapies
Dr Gerald Chodak discusses results from the ASCO National Cancer Opinion Survey.Medscape Urology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 27, 2018 Category: Consumer Health News Tags: Urology Commentary Source Type: news

Israeli Company Set To Begin Testing New Radiation Cancer Therapy
An Israeli medical technology company is set to begin testing a new radiation cancer therapy, that kills cancer cells while sparing surrounding tissue, in leading medical centers in Italy. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - November 26, 2018 Category: Pharmaceuticals Authors: Robin Seaton Jefferson, Contributor Source Type: news

Beaverton lab identifies drug that turns off key gene in deadly childhood muscle cancer
The Children's Cancer Therapy Development Institute is studying how a breast cancer drug candidate could impact children with an aggressive tumor in the soft muscle. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - November 21, 2018 Category: Pharmaceuticals Authors: Elizabeth Hayes Source Type: news

Beaverton lab identifies drug that turns off key gene in deadly childhood muscle cancer
The Children's Cancer Therapy Development Institute is studying how a breast cancer drug candidate could impact children with an aggressive tumor in the soft muscle. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 21, 2018 Category: Biotechnology Authors: Elizabeth Hayes Source Type: news

Strengthening the digital future of Berlin's cancer research
(Charit é - Universit ä tsmedizin Berlin) The doctoral program 'CompCancer - Computational Methods in Oncology: Towards Personalized Medicine in Cancer Therapies' has received approval from the German Research Foundation (DFG). As part of this research program, a new generation of researchers will be developing computer-based tools for use in cancer research. The new Research Training Group is headed by Prof. Dr. Nils Bl ü thgen of Charit é - Universit ä tsmedizin Berlin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 20, 2018 Category: International Medicine & Public Health Source Type: news

Cutting the legs off cancer
(University of Tokyo) Melanoma skin cancer tumors grow larger and are more likely to metastasize due to interactions between a pair of molecules, according to experiments in mice and human cells. The results may restore the potential for a type of cancer therapy previously abandoned in clinical trials. The results also implicate one molecule already connected to obesity and dementia as a potential cause of metastasis, or spread of cancer cells to other areas of the body. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 20, 2018 Category: Cancer & Oncology Source Type: news

Roswell Park launches partnership with Polish university
In a move that will expand research and clinical trials, Roswell Park Comprehensive Cancer Center has announced a new academic agreement with one of Europe ’s oldest educational institutions. The collaboration with the Jagiellonian University (JU) in Kraków, Poland, will include exchanges of staff, students and scientific resources to advance the development of cancer therapies for patients worldwide. Effective immediately, the deal could see excha nge of students and faculty between the two centers… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - November 15, 2018 Category: Health Management Authors: Tracey Drury Source Type: news

Roswell Park launches partnership with Polish university
In a move that will expand research and clinical trials, Roswell Park Comprehensive Cancer Center has announced a new academic agreement with one of Europe ’s oldest educational institutions. The collaboration with the Jagiellonian University (JU) in Kraków, Poland, will include exchanges of staff, students and scientific resources to advance the development of cancer therapies for patients worldwide. Effective immediately, the deal could see excha nge of students and faculty between the two centers… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 15, 2018 Category: Biotechnology Authors: Tracey Drury Source Type: news

Serious bowel diseases that blight the lives of thousands could be cured with a 'faecal transplant'
Researchers from The University of Texas MD Anderson Cancer Center found that the nauseating procedure resolved severe colitis in two patients who developed the disease following cancer therapy. (Source: the Mail online | Health)
Source: the Mail online | Health - November 12, 2018 Category: Consumer Health News Source Type: news

IIT Roorkee researchers make headway in cancer therapy
Led by P Gopinath, a team of IIT Roorkee researchers, have developed nanosized (having dimensions of a few nano meter) carbon materials have been extracted from the leaves of the rosy periwinkle plant. (Source: The Economic Times)
Source: The Economic Times - November 8, 2018 Category: Consumer Health News Source Type: news

Tumour immune cells could aid cancer therapies, study shows
(University of Edinburgh) A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 7, 2018 Category: Cancer & Oncology Source Type: news

Researchers have unlocked secrets about engineered protein receptor, CAR
(University of Southern California) Three USC Viterbi School of Engineering researchers -- Assistant Professor Stacey Finley, Professor Pin Wang and Assistant Professor Nick Graham -- have just published a paper in 'Biophysical Journal' that sheds light on Chimeric Antigen Receptor (CAR) T cell therapy, information that could one day result in better cancer therapies with fewer side effects. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 7, 2018 Category: Cancer & Oncology Source Type: news

Tumor immune cells could aid cancer therapies, study shows
(University of Edinburgh) A pioneering technique designed to spot differences between immune cells in tumors could speed the development of cancer treatments, research suggests. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 7, 2018 Category: International Medicine & Public Health Source Type: news

Tumour immune cells could aid cancer therapies
A pioneering technique designed to spot differences between immune cells in tumours could speed the development of cancer treatments, research suggests. Scientists say the approach could be used to help doctors choose the best treatments for individual patients and predict which tumours are likely to respond to a particular therapy. (Source: World Pharma News)
Source: World Pharma News - November 6, 2018 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Open source machine learning tool could help choose cancer drugs
(Georgia Institute of Technology) Using machine learning techniques, a new open source decision support tool could help clinicians choose cancer therapy drugs by analyzing RNA expression tied to information about patient outcomes with specific drugs. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 6, 2018 Category: Cancer & Oncology Source Type: news

Coverage of hormonal breast cancer therapies increased in states that expanded Medicaid
(American Association for Cancer Research) An evaluation of breast cancer patients enrolled in Medicaid showed that states that expanded Medicaid during 2011 to 2017 had a 27 percent increase in prescriptions for hormonal therapy medications compared to states that did not expand Medicaid during the same period. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 2, 2018 Category: Cancer & Oncology Source Type: news

Two-cells-in-one combo therapy could bolster leukemia treatment
(UCLA Samueli School of Engineering) A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 31, 2018 Category: Cancer & Oncology Source Type: news

Why nutrition-based therapy works better than chemotherapy for treating cancer
(Natural News) Two thousand years ago, Hippocrates said that food should be the medicine. Recent developments mirror that ancient saying when it comes to cancer therapy. An Indian study indicated that nutritional therapy possessed certain advantages over chemotherapy as a means of treating the disease. Cancer comes in many forms that attack various parts of... (Source: NaturalNews.com)
Source: NaturalNews.com - October 29, 2018 Category: Consumer Health News Source Type: news

Anti-cancer virus fits tumor receptor like a 'key in a lock'
(Okinawa Institute of Science and Technology (OIST) Graduate University) For the first time, scientists reveal how a promising drug candidate for cancer therapy interacts with receptors on tumors. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 29, 2018 Category: Cancer & Oncology Source Type: news

'Mushrooms' and 'brushes' help cancer-fighting nanoparticles survive in the body
(Drexel University) For a number of innovative and life-saving medical treatments, from organ replacements and skin grafts to cancer therapy and surgery, success often depends on slipping past or fending off the body's immune system. In a recent development, aimed at aiding cancer detection and treatment, Drexel University researchers might have found the ideal surface texture for helping microscopic, medical helpers to survive in the bloodstream without being screened out by the body's natural defense mechanisms. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 23, 2018 Category: Cancer & Oncology Source Type: news

FDA delays approval for BMS cancer therapy
Bristol-Myers said the marketing application submitted to the U.S. FDA for its Opdivo plus Yervoy cancer therapy combination will be delayed by three months, until May 2019. (Source: PharmaManufacturing.com)
Source: PharmaManufacturing.com - October 22, 2018 Category: Pharmaceuticals Source Type: news

Do Some Prostate Cancer Therapies Raise Patients ’ Risks for Bladder Cancer?
Treatment for prostate cancer with external beam radiotherapy was found to be associated with an increased risk for development of bladder cancer when compared with radical prostatectomy. (Source: CancerNetwork)
Source: CancerNetwork - October 18, 2018 Category: Cancer & Oncology Authors: Dave Levitan Source Type: news

Nanobiotix reels in $18.5m tranche from European Investment Bank
Nanobiotix (PAR:NANO.PA) received €16 million ($18.5 million) in the first tranche of a previously-announced non-dilutive loan from the European Investment Bank. The five-year funding deal is designed to support the company’s development of nanoparticle-based cancer therapies. Get the full story at our sister site, Drug Delivery Business News. The post Nanobiotix reels in $18.5m tranche from European Investment Bank appeared first on MassDevice. (Source: Mass Device)
Source: Mass Device - October 17, 2018 Category: Medical Devices Authors: Sarah Faulkner Tags: Drug-Device Combinations Funding Roundup Oncology Pharmaceuticals Wall Street Beat nanobiotix Source Type: news

Is the next big step in cancer therapy personalized vaccines?
(University of California - San Diego) Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic. Tamara enrolled in a first-of-its-kind, pilot study at Moores Cancer Center at UC San Diego Health to test a personalized vaccine using her unique cancer mutations to boost an anti-tumor immune response. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 12, 2018 Category: Biology Source Type: news

How are pulsed electric fields being used in cancer therapy?
(Mary Ann Liebert, Inc./Genetic Engineering News) Pulsed electric fields are helping fight cancer, whether by inducing tumor cell death or by stimulating the immune system. A comprehensive overview of this developing field is published in the preview issue of Bioelectricity. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 11, 2018 Category: Cancer & Oncology Source Type: news

New cancer vaccine platform a potential tool for efficacious targeted cancer therapy
(University of Helsinki) Researchers at the University of Helsinki have discovered a solution in the form of a cancer vaccine platform for improving the efficacy of oncolytic viruses used in cancer treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - October 5, 2018 Category: Cancer & Oncology Source Type: news

The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation."
Cancer kills millions of people every year and is one of humanity's greatest health challenges. By stimulating the inherent ability of our immune system to attack tumor cells this year's Nobel Laureates have established an entirely new principle for cancer therapy. (Source: World Pharma News)
Source: World Pharma News - October 1, 2018 Category: Pharmaceuticals Tags: Featured Development Research and Development Source Type: news

Medical News Today: Cancer therapy: Bacteria may help shrink tumors
A new phase I clinical trial looks at whether a modified bacterial strain is safe and effective in attacking stubborn, treatment-resistant cancer tumors. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 1, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

American and Japanese immunologists are awarded Nobel Medicine Prize
The pair (pictured) were honoured 'for their discovery of cancer therapy by inhibition of negative immune regulation,' the Stockholm-based Nobel Assembly said. (Source: the Mail online | Health)
Source: the Mail online | Health - October 1, 2018 Category: Consumer Health News Source Type: news

Landmark cancer therapy wins Nobel prize for medicine
Two scientists working on immune treatments for cancer have won the 2018 prize for physiology or medicine. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 1, 2018 Category: Consumer Health News Source Type: news

Nobel prize for medicine goes to cancer therapy
Two scientists working on immune treatments for cancer have won the 2018 prize for physiology or medicine. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 1, 2018 Category: Consumer Health News Source Type: news

James P. Allison, Tasuku Honjo Win 2018 Nobel Prize In Physiology Or Medicine
The pair of immunologists won for their discovery of cancer therapy that works by harnessing the body's own immune system. (Source: NPR Health and Science)
Source: NPR Health and Science - October 1, 2018 Category: Consumer Health News Authors: Joe Neel Source Type: news

2018 Nobel Medicine Prize awarded for cancer research
James Allison and Tasuku Honjo won the 2018 Nobel Prize for Physiology or Medicine for discoveries leading to breakthroughs in cancer therapy, the award-giving body said on Monday. (Source: Reuters: Health)
Source: Reuters: Health - October 1, 2018 Category: Consumer Health News Tags: healthNews Source Type: news

Landmark cancer therapy wins Nobel prize
Two scientists working on immune treatments for cancer have won the 2018 prize for physiology or medicine. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 1, 2018 Category: Consumer Health News Source Type: news

The Nobel Prize in medicine awarded to two cancer immunotherapy researchers
The 2018 Nobel Prize in physiology or medicine recognizes James P. Allison and Tasuku Honjo for “their discovery of cancer therapy by inhibition of negative immune regulation.” This is a developing story. It will be updated. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - October 1, 2018 Category: Consumer Health News Authors: The Washington Post Staff Source Type: news

2 Immunologists Win 2018 Nobel Prize In Physiology Or Medicine
James P. Allison, 70, and Tasuku Honjo, 76, won the prize for their discovery of cancer therapy that works by harnessing the body's own immune system. (Source: NPR Health and Science)
Source: NPR Health and Science - October 1, 2018 Category: Consumer Health News Authors: Richard Harris Source Type: news

Medical News Today: Some cancer therapies may avert cardiovascular disease
Drugs that are currently used for cancer may thwart cardiovascular disease, the leading cause of death worldwide, according to a new study. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 29, 2018 Category: Consumer Health News Tags: Cardiovascular / Cardiology Source Type: news

U.S.-Cuban Biotech Venture Created to Bring New Cancer Therapies to USA U.S.-Cuban Biotech Venture Created to Bring New Cancer Therapies to USA
U.S. and Cuban research institutes said on Wednesday they were creating the first joint U.S.-Cuban biotech venture to be headquartered on the Communist-run island to bring new cancer therapies to U.S. patients.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 27, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

U.S.-Cuban biotech venture created to bring new cancer therapies to USA
U.S. and Cuban research institutes said on Wednesday they were creating the first joint U.S.-Cuban biotech venture to be headquartered on the Communist-run island to bring new cancer therapies to U.S. patients. (Source: Reuters: Health)
Source: Reuters: Health - September 26, 2018 Category: Consumer Health News Tags: healthNews Source Type: news