Core Gut Bacteria Analysis of Healthy Mice
Conclusion
In conclusion, our results exhibited a relatively complete picture of core gut bacteria in healthy mice that they were mainly composed of carbohydrate- and amino acids-metabolizing bacteria and immunomodulatory bacteria, as well as their ecological relationships of symbiosis or functional redundancy. It was worth noting that the core bacteria resident in healthy gut was of fundamental importance for not only the healthy physiological characteristics, but also the chronic metabolic disease phenotypes. Our study focused on the gut microbiota of healthy host, and would be an important complement to the case–control study. Although this list of healthy core gut bacteria may need to supplement and correct by more researches, especially human studies, and extend from taxon core ones to functional core ones, it could be a treasury to screen the probiotics candidates or fecal microbial transplantation components for prevention and treatment of the diseases.
Author Contributions
XW and JW designed the research. JS and JW provided the data sets. JW, TL, and JD analyzed the data. LT and JW discussed and interpreted the results. JW, TL, and LT wrote and revised the manuscript.
Funding
This work was supported by grants from National Natural Science Foundation of China (Grant No. 81600409) and Shanghai General Hospital (Grant No. 06N1702003).
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or finan...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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