Risankizumab Has Early and Lasting Benefits in Crohn's Disease Risankizumab Has Early and Lasting Benefits in Crohn's Disease
Risankizumab takes effect within the first few weeks and has enduring effects in Crohn's disease, phase 3 trials suggest.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 28, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

New Analyses Suggest Favorable Results for STELARA ® (ustekinumab) When Used as a First-Line Therapy for Bio-Naïve Patients with Moderately to Severely Active Crohn’s Disease and Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 25, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from two new analyses of STELARA® (ustekinumab) for the treatment of adults with moderately to severely active Crohn’s disease (CD) and ulcerative colitis (UC).1,2 In a modelled analysisa focused on treatment sequencing using data from randomized controlled trials, network meta-analysis and literature, results showed patient time spent in clinical remission or response was highest when STELARA was used as a first-line advanced therapy for bio-naïve patients with moderately t...
Source: Johnson and Johnson - October 25, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Crohn’s disease: The food increasing your risk of the condition by 80 percent - BMJ study
INFLAMMATORY bowel disease is an umbrella term used to describe two separate conditions caused by a malfunctioning immune system. Both ulcerative and Crohn's disease are characterised by chronic inflammation and irritation in the lining of the digestive tract. (Source: Daily Express - Health)
Source: Daily Express - Health - October 19, 2021 Category: Consumer Health News Source Type: news

Crohn's Disease: No Decline in Stomas Despite Anti-TNF Therapy Crohn's Disease: No Decline in Stomas Despite Anti-TNF Therapy
Despite the increasing use of anti –TNF medications and a low rate of proctectomy, a recent analysis finds no decline in stoma incidence among patients.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - October 13, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Crohn's Disease: No Decline in Stomas With Anti-TNF Therapy Crohn's Disease: No Decline in Stomas With Anti-TNF Therapy
Despite the increasing use of anti –TNF medications and a low rate of proctectomy, a recent analysis finds no decline in stoma incidence among patients.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 13, 2021 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

What Is Crohn's Disease?
Title: What Is Crohn's Disease?Category: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 10/13/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - October 13, 2021 Category: Nutrition Source Type: news

Janssen Submits Application Seeking U.S. FDA Approval of STELARA ® (ustekinumab) for the Treatment of Pediatric Patients With Juvenile Psoriatic Arthritis
HORSHAM, PENNSYLVANIA, October 8, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking expanded approval of STELARA® (ustekinumab) to treat pediatric patients ages 5 years and older with juvenile psoriatic arthritis (jPsA).The filing is supported by extrapolation of data from nine studies across both adult trials in active PsA and adult and pediatric studies in moderate to severe plaque psoriasis, totaling 3,997 patients evaluated across these closely associa...
Source: Johnson and Johnson - October 8, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

How to Maintain Your Social Life When You Have IBD
About two years ago, as Samantha Plevney was dealing with a major Crohn’s disease flare-up, she decided to tell her gastroenterologist how it was affecting her emotional health. “I told him that I’m alive but I’m not living,” she recalls. “Not being able to see my friends because of the uncertainty of my health situation was making me feel worse. I think people with IBD, and their doctors, tend to focus on physical symptoms, and for good reason. But the mental-health effect that comes from social support is huge.” Inflammatory bowel disease (IBD) encompasses two conditions—Cr...
Source: TIME: Health - October 5, 2021 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Source Type: news

New Analysis Presented by Janssen at United European Gastroenterology Week (UEGW) Demonstrates Long-Term Safety Profile for STELARA ® (ustekinumab) in Older Patients Across Approved Indications
SPRING HOUSE, PENNSYLVANIA, October 4, 2021 – Today, the Janssen Pharmaceutical Companies of Johnson & Johnson announced a new analysis of STELARA® (ustekinumab) pooled safety data from 13 clinical studies across approved indications, showing rates of key safety events among adults 60 years and older treated with STELARA for up to five yearsa were similar to rates observed with placebo during the control phase of these trials.1,b Approved indications included adults with moderately to severely active Crohn’s disease (CD), moderately to severely active ulcerative colitis (UC), moderate to severe plaque p...
Source: Johnson and Johnson - October 4, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

How Do You Get Crohns
How Do You Get Crohn's Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - October 1, 2021 Category: General Medicine Source Type: news

Crohn’s disease: Stomach condition causes eye disorders – four symptoms to spot
CROHN'S disease can affect people of all ages, including children with roughly 115,000 people in the UK suffering from it. Early symptoms can strangely be found in the eyes with any of these four signs warning you may be heading for it. (Source: Daily Express - Health)
Source: Daily Express - Health - September 30, 2021 Category: Consumer Health News Source Type: news

Crohn's disease: Five symptoms that could prove life-threatening if not treated early
CROHN'S disease is a chronic condition where parts of the digestive system become inflamed. Though various studies have looked into the causes of Crohn's disease, the actual cause is unknown. However, scientists do know that it is one type of a condition known as inflammatory bowel disease . If Crohn's disease is not diagnosed, fatal complications can result. In rare cases, these complications can be fatal. (Source: Daily Express - Health)
Source: Daily Express - Health - September 29, 2021 Category: Consumer Health News Source Type: news

Crohn's disease symptoms: The sign on your skin you could have the lifelong condition
CROHN'S disease is a lifelong condition where parts of the digestive system become inflamed. There are several symptoms to be aware of, including some which could occur on your skin. (Source: Daily Express - Health)
Source: Daily Express - Health - September 26, 2021 Category: Consumer Health News Source Type: news

Do you suffer with IBS? Your symptoms could be a sign of a more serious condition - expert
IRRITABLE bowel syndrome causes abdominal symptoms that include constipation, diarrhoea, or both. However, the condition does not damage a person's bowel like ulcerative colitis or Crohn's disease can. Symptoms can consist of flare ups that can cause excruciating pain and can make going about your daily life uncomfortable. For years, IBS has often been diagnosed before another, more serious condition. (Source: Daily Express - Health)
Source: Daily Express - Health - September 25, 2021 Category: Consumer Health News Source Type: news

Can Cannabis Help Your Gut?
When Joe Silverman developed Crohn’s disease at age 21, the symptoms started out mild. While the sight of blood in his stools initially freaked him out, what really bothered him was the frequent abdominal pain and bloating that occurred as his condition progressed to moderate and then severe. Dietary changes didn’t make a difference, so he began taking prescription oral anti-inflammatory drugs that are often used to treat certain bowel diseases, which alleviated but didn’t eliminate his discomfort. He started using prescription steroid suppositories to cope with flare-ups of the inflammatory bowel disease...
Source: TIME: Health - September 23, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Source Type: news

Crohn’s disease: Pain felt on a certain area of the tummy could be a warning symptom
CROHN'S disease typically appears in younger people - often in their late teens, 20s or early 30s. However, the condition can also occur at any age. The location of your pain is a major warning sign, indicating your risk. (Source: Daily Express - Health)
Source: Daily Express - Health - September 13, 2021 Category: Consumer Health News Source Type: news

Subcutaneous Vedolizumab Appears to Be Effective Maintenance Therapy in Crohn's Disease Subcutaneous Vedolizumab Appears to Be Effective Maintenance Therapy in Crohn's Disease
Subcutaneous vedolizumab appears to be an effective and safe maintenance therapy for some patients with moderate to severe active Crohn's disease, according to results of a phase-3 trial.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - September 10, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Fecal Transplants: a New Treatment for IBD
Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV ste...
Source: TIME: Health - September 9, 2021 Category: Consumer Health News Authors: Stacey Colino Tags: Uncategorized Disease feature Source Type: news

What Triggers Crohns Disease
What Triggers Crohn's Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - August 31, 2021 Category: General Medicine Source Type: news

Early Infliximab Could Change the Course of Crohn's Disease Early Infliximab Could Change the Course of Crohn's Disease
Starting infliximab early after diagnosis boosts the chance of achieving endoscopic remission and reduces the development of stenosis over the next 2 years, report clinicians from Germany.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 27, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Ultrasound Detects Ulcerative Colitis Disease Activity
FRIDAY, Aug. 27, 2021 -- A new ulcerative colitis intestinal ultrasound (UC-IUS) index shows strong correlation with endoscopy for detection of disease activity, according to a study published in the August issue of the Journal of Crohn's and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 27, 2021 Category: Pharmaceuticals Source Type: news

Outcome Measure Developed for Crohn's Perianal Fistula
WEDNESDAY, Aug. 25, 2021 -- A patient-reported outcome measure (PROM) has been developed for Crohn's perianal fistula, which has good internal consistency, excellent stability, and good responsiveness and construct validity, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 25, 2021 Category: Pharmaceuticals Source Type: news

Adalimumab Biosimilar on Par With Original in Crohn's Disease Adalimumab Biosimilar on Par With Original in Crohn's Disease
For patients with moderate to severe active Crohn's disease, the adalimumab biosimilar BI 695501 from Boehringer Ingelheim proved as safe and effective as the original, AbbVie's Humira, in the phase-3 VOLTAIRE-CD study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 20, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Persistence With Biologics in Inflammatory Bowel Diseases Persistence With Biologics in Inflammatory Bowel Diseases
This study aimed to analyze persistence of biological agents in Crohn's disease and ulcerative colitis. What factors might influence treatment persistence?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 18, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Efficacy of Escalated Anti-TNF Therapy in Crohn's Disease Efficacy of Escalated Anti-TNF Therapy in Crohn's Disease
Is dose escalation of anti-TNF therapy effective for reestablishing clinical response in Crohn's disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 16, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

How Is Crohn's Different From IBS?
Title: How Is Crohn's Different From IBS?Category: Diseases and ConditionsCreated: 8/3/2021 12:00:00 AMLast Editorial Review: 8/3/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 3, 2021 Category: Nutrition Source Type: news

VTE Risk Up for Children With Inflammatory Bowel Disease
Venous thromboembolism occurred less often for those with Crohn disease versus ulcerative colitis (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - July 27, 2021 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Pediatrics, Pharmacy, Journal, Source Type: news

VTE Risk Up for Children With Inflammatory Bowel Disease
TUESDAY, July 27, 2021 -- Children with inflammatory bowel disease (IBD) have a higher risk for venous thromboembolism (VTE), according to a study published online June 27 in the Journal of Crohn's& Colitis. M. Ellen Kuenzig, Ph.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 27, 2021 Category: Pharmaceuticals Source Type: news

Fifteen years in the making, biotech lands in Bay Area with fresh funding from Hyatt heirs and plan to change direction of inflammatory diseases
Giant drug maker Bristol-Myers Squibb and a string of investment vehicles led by heirs of the Hyatt Hotels fortune invested in a North Bay company tapping deep patient data to move faster to discover and develop drugs against lupus, Crohn's disease and other inflammatory diseases. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 27, 2021 Category: Biotechnology Authors: Ron Leuty Source Type: news

Jeff Hordley health: Wife Zoe Henry opens up about soap star's lifelong health condition
JEFF HORDLEY, 51, is instantly recognisable as Cain Dingle in the ITV soap opera Emmerdale, but he has also made a name for himself as an ardent campaigner for Crohn's disease - a condition he has lived with for decades. A couple of years back, the soap star's wife Zoe Henry, 47, shed further light on his chronic condition. (Source: Daily Express - Health)
Source: Daily Express - Health - July 26, 2021 Category: Consumer Health News Source Type: news

What Are the Best Foods to Eat With Crohn ’s Disease?
Title: What Are the Best Foods to Eat With Crohn ’s Disease?Category: Diseases and ConditionsCreated: 7/21/2021 12:00:00 AMLast Editorial Review: 7/21/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 21, 2021 Category: Nutrition Source Type: news

What Are the Warning Signs of Crohn ’s Disease?
Title: What Are the Warning Signs of Crohn ’s Disease?Category: Diseases and ConditionsCreated: 7/21/2021 12:00:00 AMLast Editorial Review: 7/21/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 21, 2021 Category: Nutrition Source Type: news

What Are the Symptoms of Crohn ’s Disease in a Child?
Title: What Are the Symptoms of Crohn ’s Disease in a Child?Category: Diseases and ConditionsCreated: 7/21/2021 12:00:00 AMLast Editorial Review: 7/21/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 21, 2021 Category: Nutrition Source Type: news

Does Crohn ’s Disease Weaken Your Immune System?
Title: Does Crohn ’s Disease Weaken Your Immune System?Category: Diseases and ConditionsCreated: 7/21/2021 12:00:00 AMLast Editorial Review: 7/21/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 21, 2021 Category: Nutrition Source Type: news

Is Crohn's Disease Related to Rheumatoid Arthritis?
Title: Is Crohn's Disease Related to Rheumatoid Arthritis?Category: Diseases and ConditionsCreated: 7/20/2021 12:00:00 AMLast Editorial Review: 7/20/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 20, 2021 Category: Nutrition Source Type: news

Can Crohn's Disease Be Cured With Surgery?
Title: Can Crohn's Disease Be Cured With Surgery?Category: Procedures and TestsCreated: 7/13/2021 12:00:00 AMLast Editorial Review: 7/13/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 13, 2021 Category: Nutrition Source Type: news

STELARA ® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Rates in Adults with Moderately to Severely Active Ulcerative Colitis at Nearly Three Years in Long-Term Extension of Phase 3 Trial
SPRING HOUSE, PENNSYLVANIA, July 9, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new three-year data from the long-term extension (LTE) of the STELARA® (ustekinumab) Phase 3 UNIFI study. The data demonstrated the majority (55.2 percent) of adult patients with moderately to severely active ulcerative colitis (UC) who initially responded to treatment with STELARA sustained symptomatic remissiona rates at nearly three years (week 152).1 Furthermore, a majority (96.4 percent) of the patients in symptomatic remissiona at week 152 were corticosteroid-free. These data are being pr...
Source: Johnson and Johnson - July 9, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

For pediatric patients with Crohn's disease, factors associated with statural growth differ by sex
(Weill Cornell Medicine) Growth impairment, a common complication of Crohn's disease in children, occurs more often in males than females, but the reasons are unclear. Now, a physician-scientist from Weill Cornell Medicine and NewYork-Presbyterian and colleagues at eight other centers have found that factors associated with statural growth differ by sex. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 9, 2021 Category: International Medicine & Public Health Source Type: news

Contrast-Free Imaging Can Spot Postop Crohn's Recurrence Contrast-Free Imaging Can Spot Postop Crohn's Recurrence
For the diagnosis of postoperative recurrence of Crohn's disease at the anastomotic site, diffusion-weighted magnetic resonance enterography (MRE) is on par with contrast-enhanced MRE, report radiologists from France.Reuters Health Information (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - June 28, 2021 Category: Radiology Tags: Gastroenterology News Source Type: news

Crohn ’s Disease vs Ulcerative Colitis Difference
Crohn ’s Disease vs. Ulcerative Colitis: What's the Difference? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 21, 2021 Category: General Medicine Source Type: news

Guidelines: Management of Moderate to Severe Crohn's Disease Guidelines: Management of Moderate to Severe Crohn's Disease
The AGA released guidelines for adult outpatients with moderate to severe Crohn's disease, strongly recommending induction and maintenance therapy with anti-TNF-alpha agents or ustekinumab.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - June 16, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

COVID Vaccines Appear Safe for People With IBD
THURSDAY, June 10, 2021 -- The Pfizer and Moderna COVID-19 vaccines appear to be safe for people with inflammatory bowel diseases (IBD), a new study finds. IBDs -- which includes Crohn's disease and ulcerative colitis -- are chronic conditions... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 10, 2021 Category: General Medicine Source Type: news

Diets Compared for Mild-to-Moderate Crohn Disease in Adults
WEDNESDAY, June 9, 2021 -- The specific carbohydrate diet (SCD) is not superior to the Mediterranean diet (MD) for the remission of symptoms in adults with mild-to-moderate Crohn disease (CD), according to a study published online May 26 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 9, 2021 Category: Pharmaceuticals Source Type: news

What Diet Is Most Likely to Help Ease Crohn's Disease?
Title: What Diet Is Most Likely to Help Ease Crohn's Disease?Category: Health NewsCreated: 6/8/2021 12:00:00 AMLast Editorial Review: 6/9/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 9, 2021 Category: Nutrition Source Type: news

What Diet Is Most Likely to Help Ease Crohn's Disease?
TUESDAY, June 8, 2021 -- People who have Crohn's disease often seek to ease their symptoms by changing what they eat, and new research suggests the Mediterranean diet may be their best bet. The study evaluated one of the commonly used diets for... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 8, 2021 Category: General Medicine Source Type: news

AGA Issues Recommendations for Moderate-to-Severe Crohn Disease
FRIDAY, June 4, 2021 -- In clinical practice guidelines from the American Gastroenterological Association (AGA) published in the June 1 issue of Gastroenterology, recommendations are presented for the management of moderate-to-severe luminal and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 4, 2021 Category: Pharmaceuticals Source Type: news

What Are Best Foods to Eat with Crohn's Disease
What Are the Best Foods to Eat with Crohn's Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 4, 2021 Category: General Medicine Source Type: news

What Are the Warning Signs of Crohns Disease
What Are the Warning Signs of Crohn ’s Disease? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 4, 2021 Category: General Medicine Source Type: news

SEAVUE: Ustekinumab vs Adalimumab for Crohn's Disease SEAVUE: Ustekinumab vs Adalimumab for Crohn's Disease
For biologic-naive adults with moderate to severe Crohn's disease, treatment with either adalimumab or ustekinumab leads to similar outcomes, according to results of the head-to-head SEAVUE trial.Medscape Medical News (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 28, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

'Good' bacteria show promise for clinical treatment of Crohn's disease, ulcerative colitis
(University of North Carolina Health Care) Balfour Sartor, MD, Midget Distinguished Professor of Medicine, Microbiology and Immunology, is the senior author of a study that shows how a novel consortium of bacteria that live in the digestive tracts of healthy individuals can be used to prevent and treat aggressive colitis in humanized mouse models. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 28, 2021 Category: International Medicine & Public Health Source Type: news