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Tipping the balance: How one strain of bacteria affects its neighbors in Crohn's disease
(American Association for the Advancement of Science) A new study suggests a single strain of bacteria can reconfigure entire communities of microbes that make up the gut microbiota. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - November 15, 2017 Category: Infectious Diseases Source Type: news

Colon cancer breakthrough could lead to prevention - and the foods that can help
Colon cancer, Crohn's, and other diseases of the gut could be better treated - or even prevented - thanks to a new link between inflammation and a common cellular process, established by the University of Warwick. Led by Dr Ioannis Nezis at Warwick's School of Life Sciences, new research demonstrates that autophagy - an essential process whereby cells break down and recycle harmful or damaged elements within themselves to keep our bodies healthy - causes tissue inflammation when dysfunctional, which in turn leaves us susceptible to harmful diseases, particularly in the gut. (Source: World Pharma News)
Source: World Pharma News - November 8, 2017 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

What Causes White Nails?
Discussion The nail matrix covers the area of the nail plate, and extends proximally in a crescent moon shape with the edges of the crescent extending proximally and inferiorly toward the underlying bone. The nail matrix is a multilayered epithelium that physiologically produces keratinization and gives rise to the nail plate. The distal matrix forms the lower 2/3s of the nail plate and the proximal matrix forms the upper 1/3 of the nail plate. the thickness of the nail plate is proportion to the matrix’s thickness. The nail plate’s free edge contour follows the shape of the nail’s lunula. Melanocytes occ...
Source: PediatricEducation.org - November 6, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

X Factor's Lloyd Macey says singing helps Crohn's disease
The 23-year-old Welshman, who has reached the live finals of this year ’s competition, has told of his dramatic six-year battle with Crohn’s. (Source: the Mail online | Health)
Source: the Mail online | Health - November 5, 2017 Category: Consumer Health News Source Type: news

New colon cancer breakthrough may lead to prevention
Researchers at the University of Warwick have found that a natural body process can cause inflammation, increasing the risk of colon cancer and Crohn's disease. (Source: Health News - UPI.com)
Source: Health News - UPI.com - November 3, 2017 Category: Consumer Health News Source Type: news

Living with NASH: An Unexpected Diagnosis
As our waistlines thicken and our activity levels decrease, another chronic illness threatens to disturb our comfortable lifestyles. And, because it ’s relatively unknown, diagnosis comes as a shock to patients, who usually associate liver disease with heavy consumption of alcohol.Non-alcoholic steatohepatitis (NASH) is an advanced form of non-alcoholic fatty liver disease (NAFLD), where fat accumulates in the liver. It is most commonly associated with obesity, insulin resistance, metabolic syndrome and/or genetic polymorphisms, and is aggravated by inflammation and fibrosis.  First identified in the 1980s, its ...
Source: EyeForPharma - November 3, 2017 Category: Pharmaceuticals Authors: Mariel Metcalfe Source Type: news

Medical News Today: The 10 best Crohn's disease blogs
Crohn's disease blogs can be a useful source of educational information on the condition and contain tips and accounts from individuals with the disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 2, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Colon cancer breakthrough could lead to prevention -- and the foods that can help
(University of Warwick) Colon cancer, Crohn's, and other diseases of the gut could be better treated -- or even prevented -- thanks to a new link between inflammation and a common cellular process, established by the University of Warwick. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - November 2, 2017 Category: Cancer & Oncology Source Type: news

Crohn's: Smoking can cause agonising bowel condition that brings misery to thousands
SMOKING can trigger an agonising digestive condition that blights the lives of tens of thousands of Britons, according to new research. (Source: Daily Express - Health)
Source: Daily Express - Health - October 31, 2017 Category: Consumer Health News Source Type: news

Smoking cigarettes may cause Crohn's disease
Scientists at Kyung Hee University, Seoul, discovered mice who inhaled cigarette smoke showed signs of intestinal inflammation - a sign of Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - October 31, 2017 Category: Consumer Health News Source Type: news

Smoking may cause inflammatory bowel disease
(Frontiers) A new study shows for the first time a direct effect of cigarette smoke on bowel inflammation. The researchers find that mice exposed to cigarette smoke develop a type of colitis resembling Crohn's disease. The researchers also identified a specific immune cell responsible for the effect. These findings could help scientists develop new treatments for inflammatory bowel diseases, such as Crohn's disease, and increase awareness among smokers of their risk for colitis. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - October 31, 2017 Category: International Medicine & Public Health Source Type: news

A 17-year-old with schizophrenia and uncontrollable anxiety after a suicide attempt - Blain K, Magid M.
A 17-year-old boy with a history of schizophrenia, asthma, and Crohn's disease was brought to the emergency department (ED) by his aunt after a suicide attempt in which he lit his bedroom on fire. After 20 minutes in the burning room, he aborted the attemp... (Source: SafetyLit)
Source: SafetyLit - October 30, 2017 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Some GI disorders get disproportionate share of U.S. research funding
(Reuters Health) - Gastrointestinal (GI) disorders such as Crohn ’s disease and Barrett’s esophagus get a bigger slice of U.S. public research funding than other GI conditions that affect many more Americans, researchers say. (Source: Reuters: Health)
Source: Reuters: Health - October 26, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

The selfie campaign urging you to 'Get Your Belly Out'
Meet the women who set up the campaign for people with Crohn's and colitis. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - October 25, 2017 Category: Consumer Health News Source Type: news

Protein regulates vitamin A metabolic pathways, prevents inflammation
(Case Western Reserve University) A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation. The discovery links diet to inflammatory diseases, like Crohn's disease and inflammatory bowel syndromes, and could inform nutritional interventions. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - October 23, 2017 Category: Biology Source Type: news

Celgene Provides Update on GED-0301 (mongersen) Inflammatory Bowel Disease Program
SUMMIT, N.J.--(Healthcare Sales & Marketing Network)-- Celgene Corporation (NASDAQ: CELG) today announced that the GED-0301 (mongersen) phase III REVOLVE trial (CD-002) in Crohn's disease (CD) and the extension trial (SUSTAIN, CD-004) will discontinue. Cel... Biopharmaceuticals, Gastroenterology Celgene, mongersen, REVOLVE trial, Crohn's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - October 20, 2017 Category: Pharmaceuticals Source Type: news

Celgene abandons Crohn's drug trials, shares drop
(Reuters) - Celgene Corp said it would abandon testing a drug to treat Crohn's disease, in a major setback to the U.S. biotechnology company's pipeline amid attempts to lower dependence on its mainstay Revilimid. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Celgene to stop testing Crohn's drug, shares drop
(Reuters) - Celgene Corp said it would abandon testing a drug to treat Crohn's disease, an inflammatory bowel disease, following a risk-benefit analysis by a data monitoring committee, in a major setback to the drugmaker's pipeline. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Celgene abandons Crohn's disease drug trials
(Reuters) - Celgene Corp said on Thursday it would stop two studies of its drug for an inflammatory bowel disease and would not begin a third, following a recommendation by a data monitoring committee. (Source: Reuters: Health)
Source: Reuters: Health - October 19, 2017 Category: Consumer Health News Tags: healthNews Source Type: news

Fungus may play key role in Crohn's, chronic intestinal inflammation
Researchers at Case Western University have found that fungi in combination with bacteria play a vital role in chronic intestinal inflammation disorders. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 4, 2017 Category: Consumer Health News Source Type: news

Medical News Today: New IBD treatments may combine antifungals and probiotics
A review suggests that gut fungi, along with bacteria, play a key role in gut health, and new treatments for IBD may combine antifungals with probiotics. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 4, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Leaky gut symptoms: Five health problems that could be caused by the MYSTERIOUS syndrome
LEAKY gut syndrome is a controversial condition said to be the cause of arthritis, coeliac disease and Crohn ’s disease. What are the signs? (Source: Daily Express - Health)
Source: Daily Express - Health - September 25, 2017 Category: Consumer Health News Source Type: news

Surgery an Alternative to Infliximab for Some People With Crohn ’ s Disease Surgery an Alternative to Infliximab for Some People With Crohn ’ s Disease
Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - September 21, 2017 Category: Surgery Tags: General Surgery News Source Type: news

Medical News Today: Cancer risk higher in children with inflammatory bowel disease
Researchers find that childhood inflammatory bowel disease is linked to higher risk of cancer - especially gastrointestinal - that persists into adulthood. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 21, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Inflammatory Bowel Disease May Raise Cancer Risk in Kids
Researchers think chronic inflammation in gastrointestinal tract may be driving forceSource: HealthDay Related MedlinePlus Pages: Cancer in Children, Crohn's Disease, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - September 21, 2017 Category: Consumer Health News Source Type: news

Crohn's & Colitis Congress offers reporters access to leading IBD research
(American Gastroenterological Association) The Crohn's& Colitis Foundation and the American Gastroenterological Association (AGA) are partnering to co-sponsor the first-ever Crohn's& Colitis Congress, ™ which will take place in Las Vegas in January 2018.The Crohn's& Colitis Congress is the premier conference for inflammatory bowel diseases (IBD) health-care professionals and researchers. It brings state-of-the-art comprehensive care together with the latest research to advance prevention, treatment and cures for IBD patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 20, 2017 Category: International Medicine & Public Health Source Type: news

Crohn's & Colitis Foundation and Oxford University Press enter into publishing partnership
(Oxford University Press USA) The Crohn's& Colitis Foundation and Oxford University Press announced today that they have entered into a new partnership to publish the Foundation's journal Inflammatory Bowels Diseases beginning in 2018. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 19, 2017 Category: International Medicine & Public Health Source Type: news

Mesenchymal stem cells offer novel treatment approach for Crohn's disease fistula
(Mary Ann Liebert, Inc./Genetic Engineering News) A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells (MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe and effective addition to surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2017 Category: International Medicine & Public Health Source Type: news

The Efficacy of Probiotics in Inflammatory Bowel Disease The Efficacy of Probiotics in Inflammatory Bowel Disease
This study examined the efficacy of probiotics in inducing and maintaining remission in ulcerative colitis and Crohn disease, as well as preventing relapse in post-operative CD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 12, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The road to Crohn's disease
(Source: ScienceNOW)
Source: ScienceNOW - September 7, 2017 Category: Science Authors: Kaser, A., Blumberg, R. S. Tags: Cell Biology perspective Source Type: news

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
Intestinal Paneth cells limit bacterial invasion by secreting antimicrobial proteins, including lysozyme. However, invasive pathogens can disrupt the Golgi apparatus, interfering with secretion and compromising intestinal antimicrobial defense. Here we show that during bacterial infection, lysozyme is rerouted via secretory autophagy, an autophagy-based alternative secretion pathway. Secretory autophagy was triggered in Paneth cells by bacteria-induced endoplasmic reticulum (ER) stress, required extrinsic signals from innate lymphoid cells, and limited bacterial dissemination. Secretory autophagy was disrupted in Paneth ce...
Source: ScienceNOW - September 7, 2017 Category: Science Authors: Bel, S., Pendse, M., Wang, Y., Li, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J., Hooper, L. V. Tags: Cell Biology reports Source Type: news

Old Crohn's Theory Relevant Now? Gastro Endo News Report
(MedPage Today) -- Also, proton pump inhibitors and pancreatic cancer link (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 6, 2017 Category: Gastroenterology Source Type: news

Eat seasonal produce for better gut health says experts
The Hadza tribes living in the Savannah have more  diverse gut bacteria, found Stanford researchers. They don't get the gut ailments that we do such as Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2017 Category: Consumer Health News Source Type: news

Asthma Tied to Later Inflammatory Bowel Disease
Findings for Crohn's and early - or late - onset ulcerative colitis (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 25, 2017 Category: Respiratory Medicine Tags: Gastroenterology, Internal Medicine, Allergy, Pathology, Pulmonology, Journal, Source Type: news

Eat seasonal produce for better gut health
The Hadza tribes living in the Savannah have more  diverse gut bacteria, found Stanford researchers. They don't get the gut ailments that we do such as Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2017 Category: Consumer Health News Source Type: news

Lab tests show molecule appears to spur cell death in tumors, inflammation
(Duke University Medical Center) A drug-like molecule developed by Duke Health researchers appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn's disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 17, 2017 Category: Cancer & Oncology Source Type: news

Prophylaxis in Crohn's Disease After Intestinal Resection Prophylaxis in Crohn's Disease After Intestinal Resection
Can prophylactic drug therapy decrease the rate of clinical and endoscopic recurrence following intestinal resection for Crohn's disease? Which regimen may be beneficial?Frontline Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 14, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Scientists make critical insights into T-cell development
(Monash University) Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn's Disease and rheumatoid arthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

NIH grant to biomedical scientist will advance research on inflammatory bowel disease
(University of California - Riverside) Declan McCole, a biomedical scientist at the University of California, Riverside, has received a $1.83 million grant from the National Institutes of Health to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD). IBD is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

Aevi Genomic Medicine Announces Agreement for $28 Million Private Placement
PHILADELPHIA, Aug. 10, 2017 -- (Healthcare Sales & Marketing Network) -- Aevi Genomic Medicine, Inc. (NASDAQ: GNMX) (the "Company") today announced the execution of a definitive agreement to sell shares of common stock and warrants to purchase c... Biopharmaceuticals, Venture Capital Aevi Genomic Medicine, Crohn's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 10, 2017 Category: Pharmaceuticals Source Type: news

Ulcerative Colitis vs. Crohn ’s Disease – Similarities And Differences
Under normal circumstances, our immune system does its job of protecting the body from infection. However, in people who (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - August 7, 2017 Category: Consumer Health News Source Type: news

Can Diet Cause UC or Crohn's Disease?
Title: Can Diet Cause UC or Crohn's Disease?Category: Doctor's& Expert's views on SymptomsCreated: 8/4/2017 12:00:00 AMLast Editorial Review: 8/4/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 4, 2017 Category: Nutrition Source Type: news

Crohn’s disease and ulcerative colitis symptoms: What is inflammatory bowel disease?
CROHN'S disease and Ulcerative Colitis are the two main forms of Inflammatory Bowel Disease, affecting more than 300,000 people in the UK. (Source: Daily Express - Health)
Source: Daily Express - Health - August 2, 2017 Category: Consumer Health News Source Type: news

Country Kids Less Likely to Develop Bowel Disease Than Their City Cousins
Rural living may have protective effect, Canadian study suggests Source: HealthDay Related MedlinePlus Pages: Crohn's Disease, Rural Health Concerns, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 31, 2017 Category: Consumer Health News Source Type: news

UT Southwestern finds link between backup immune defense, mutation seen in Crohn's disease
(UT Southwestern Medical Center) Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 27, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: Rural living tied to lower risk of inflammatory bowel disease
A study of Canadian populations finds that living in urban households is tied to a lower chance of being diagnosed with IBD, particularly in childhood. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Crohn's disease and colitis: Where you LIVE could affect inflammatory bowel disease
CROHN ’S and colitis are the two main types of inflammatory bowel disease - IBD - and can cause painful symptoms for sufferers. While it isn’t known exactly what causes the condition, experts have now revealed it could be as a result of where you live. (Source: Daily Express - Health)
Source: Daily Express - Health - July 26, 2017 Category: Consumer Health News Source Type: news

Inflammatory bowel disease - where you LIVE could reduce Crohn’s and colitis risk
CROHN ’S and colitis are the two main types of inflammatory bowel disease - IBD - and can cause painful symptoms for sufferers. While it isn’t known exactly what causes the condition, experts have now revealed it could be as a result of where you live. (Source: Daily Express - Health)
Source: Daily Express - Health - July 26, 2017 Category: Consumer Health News Source Type: news

Merck launches biosimilar version of J & J blockbuster Remicade
Merck and Co. Inc. on Monday became the second pharmaceutical company to launch a biosimilar version of Remicade, a drug that generates billions of dollars a year in sales for Johnson& Johnson. Renflexis, the Merck biosimilar product, was approved by the Food and Drug Administration on April 21 as a treatment for rheumatoid arthritis, Crohn's disease, ulcerative colitis and ankylosing spondylitis. It is the first medicine available in the United States under a global biosimilars develop ment and… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - July 24, 2017 Category: Health Management Authors: John George Source Type: news