Vedolizumab and Malignancy Incidence Vedolizumab and Malignancy Incidence
This study analyzed the long-term incidence of malignancy with vedolizumab, a gut-selective antibody approved to treat moderate-to-severe Crohn's disease and ulcerative colitis in adults.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 22, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

IBD Diagnoses Rising in Children IBD Diagnoses Rising in Children
Advances in anti-TNF drugs will be in the spotlight at the upcoming Crohn's and Colitis Congress. One expert believes a cure will come in the lifetime of some of the children he currently treats.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 21, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Fungal Alterations in Inflammatory Bowel Diseases Fungal Alterations in Inflammatory Bowel Diseases
This review explores the role of gut fungi in patients with Crohn's disease and ulcerative colitis. Might modulation of the fungal microbiota present a therapeutic opportunity for IBD?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 15, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Crohn's Disease
Title: Crohn's DiseaseCategory: Diseases and ConditionsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 1/14/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - January 14, 2020 Category: Nutrition Source Type: news

Stopping Anti-TNF Therapy in Perianal Crohn's Disease Stopping Anti-TNF Therapy in Perianal Crohn's Disease
Does stopping anti-TNF therapy in patients with perianal Crohn's disease result in relapse?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 8, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: What to know about Crohn's and the eyes
Although most Crohn's disease symptoms involve the gut, the condition can also affect the eyes. Learn more about eye-related Crohn's symptoms here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 7, 2020 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Doctors warn Crohn's, arthritis patients will pay a price as Alberta pulls drug funding
Doctors say 2,000 patients in Alberta will pay a price with the government's plan to stop funding Remicade, a drug used to treat people with Crohn's and colitis. (Source: CBC | Health)
Source: CBC | Health - December 17, 2019 Category: Consumer Health News Tags: News/Canada/Calgary Source Type: news

Reporters invited to attend Crohn's & Colitis Congress ®
(American Gastroenterological Association) Register for the Crohn's& Colitis Congress, taking place Jan. 23-25, 2020, in Austin, Texas, and learn about the latest trends and research in inflammatory bowel disease (IBD) patient care. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 16, 2019 Category: International Medicine & Public Health Source Type: news

Biosimilar for Crohn's Noninferior to Adalimumab Biosimilar for Crohn's Noninferior to Adalimumab
A patent dispute means that the marketing of a biosimilar for patients with inflammatory bowel disease will be delayed, despite approval by the US Food and Drug Administration, investigators report.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 15, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

1999 to 2017 Saw Drop in IBD Hospitalization Rate for Whites
THURSDAY, Dec. 12, 2019 -- From 1999 to 2017, the hospitalization rate for Crohn disease and ulcerative colitis decreased among non-Hispanic white Medicare beneficiaries aged ≥65 years, but not among non-Hispanic blacks, according to research... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 12, 2019 Category: Pharmaceuticals Source Type: news

A vaccine against chronic inflammatory diseases
Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their intestinal flora along with excessive levels of bacteria that express a protein called flagellin, which favors their mobility. (Source: World Pharma News)
Source: World Pharma News - December 11, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Teams of microbes are at work in our bodies. Here's how to figure out what they're doing
(Drexel University) An algorithm akin to the annoyingly helpful one that attempts to auto-complete text messages and emails is now being harnessed for a better cause. A group of Drexel University researchers are using its pattern-recognition ability to identify microbial communities in the body by sifting through volumes of genetic code. Their method could speed the development of medical treatments for microbiota-linked ailments like Crohn's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2019 Category: International Medicine & Public Health Source Type: news

Emerging Treatment Options for Crohn's Emerging Treatment Options for Crohn's
Drug therapies and the postoperative management of patients will be in the spotlight at the upcoming Advances in Inflammatory Bowel Diseases conference.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 4, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Endoscopic Techniques for Dysplasia Surveillance in IBD Endoscopic Techniques for Dysplasia Surveillance in IBD
Which endoscopic procedure best identifies neoplasia in patients with ulcerative colitis or Crohn disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 4, 2019 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

FDA approves Pfizer's biosimilar, ABRILADA ™ (adalimumab-afzb) for multiple inflammatory conditions
Pfizer Inc. (NYSE: PFE) announced the United States (U.S.) Food and Drug Administration (FDA) has approved ABRILADA™ (adalimumab-afzb), as a biosimilar to Humira® (adalimumab),(1) for the treatment of certain patients with rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult Crohn's disease, ulcerative colitis and plaque psoriasis.(2) (Source: World Pharma News)
Source: World Pharma News - December 2, 2019 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news

Reimbursing infliximab for Crohn's disease cost effective in China
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - December 1, 2019 Category: Drugs & Pharmacology Source Type: news

Humans co-evolved with immune-related diseases -- and it's still happening
(Cell Press) Some of the same mutations allowing humans to fend off deadly infections also make us more prone to certain inflammatory and autoimmune diseases, such as Crohn's disease. In a Review published Nov. 27, 2019 in the journal Trends in Immunology, researchers describe how ancestral origins impact the likelihood that people of African or Eurasian descent might develop immune-related diseases. The authors also share evidence that the human immune system is still evolving. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 27, 2019 Category: International Medicine & Public Health Source Type: news

How Is Hidradenitis Suppurativa Treated?
Discussion Hidradenitis suppurativa (HS) is a recurrent, chronic inflammatory disease of the hair follicles particularly in the apocrine gland-bearing areas of the axilla, inguinal, perianal, mammary and inframammary areas. Onset is usually after puberty, in the early 20s. It is more common in females than males. Prevalence is estimated to be 0.05- 4.1%. It can be associated with premature adrenarche, metabolic syndrome and obesity. The lesions are often pruritic, painful, and with malodorous purulent drainage. It often begins with comedomes and tender nodules, and can easily progress to painful abscesses with purulent f...
Source: PediatricEducation.org - November 25, 2019 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Medical News Today: How do doctors test for Crohn's disease?
Crohn ’s disease is a type of inflammatory bowel disease. There is no single test for diagnosing it. A doctor might order a few different tests to confirm a diagnosis. Here, learn how doctors test for and diagnose Crohn’s disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 16, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

How Crohn's disease-associated bacteria tolerate antibiotics
(PLOS) Bacteria associated with Crohn's disease rely on multiple stress responses to survive, multiply, and tolerate antibiotics within white blood cells called macrophages, according to a study published November 14, 2019 in the open-access journal PLOS Pathogens by Olivier Esp é li of the College de France and PSL Research University in Paris, France, and colleagues. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 14, 2019 Category: International Medicine & Public Health Source Type: news

Crohn's Disease May Not Be a Contraindication to Hemorrhoidectomy Crohn's Disease May Not Be a Contraindication to Hemorrhoidectomy
Excisional hemorrhoidectomy may be a viable treatment option in patients with Crohn's disease who have failed nonoperative hemorrhoidal therapy, according to a retrospective study.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - November 13, 2019 Category: Surgery Tags: Gastroenterology News Source Type: news

Medical News Today: 13 snack ideas for Crohn's disease
Crohn ’s is an inflammatory bowel disease, and adjusting the diet can help reduce and prevent symptoms. Learn about the best snacks for people with Crohn’s disease here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 8, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Medical News Today: What are the 5 types of Crohn's disease?
Crohn ’s disease is an inflammatory bowel disorder. There are five types of Crohn’s disease, depending on symptoms and what part of the digestive tract they affect. Here, we explain the types and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 8, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

University of Cincinnati finds new option for liver transplant patients
(University of Cincinnati) Budesonide, a drug commonly used to treat Crohn's Disease, may offer fewer side effects and work at least as well as prednisone as an anti-organ rejection medication in liver transplant patients. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 8, 2019 Category: International Medicine & Public Health Source Type: news

Medical News Today: What to know about Crohn's disease and intestinal strictures
Crohn ’s disease can sometimes lead to health complications, such as intestinal strictures. Read this article to learn more about the formation of intestinal strictures, the symptoms, and how to treat them. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 7, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Medical News Today: Upset stomach: Crohn's disease or something else?
An upset stomach can have many causes, including Crohn ’s disease. Read this article for more information on how to tell whether the cause of an upset stomach is Crohn’s disease or something else. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 6, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Jeff Hordley health: Emmerdale star’s chronic condition caused him ‘horrendous’ pain
JEFF HORDLEY is best known for his portrayal of Cain Dingle in the ITV soap Emmerdale, a role he has played since 2000. Throughout his time on the show, Jeff has been living with Crohn ’s disease - what the symptoms and how can the condition be treated? (Source: Daily Express - Health)
Source: Daily Express - Health - November 6, 2019 Category: Consumer Health News Source Type: news

Medical News Today: How does alcohol affect Crohn's disease?
Alcohol and many other foods and drinks can cause flare-ups for people with Crohn ’s disease. Here, learn more about the relationship between alcohol and Crohn’s, what the research says, and how to manage the symptoms. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 30, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Medical News Today: How blood vessel health may drive IBD
Researchers have found that blood vessels likely contribute to the development of inflammatory bowel diseases. The finding also suggests novel treatments. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 11, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

IBD Patients Have High Exposure to Ionizing Radiation IBD Patients Have High Exposure to Ionizing Radiation
Patients in Ontario with inflammatory bowel disease (IBD), and particularly those with Crohn's disease (CD), are at risk for high exposure to ionizing radiation from abdominal computed tomography (CT) scanning, an observational study reveals.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 9, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

DDT COA #000034: Crohn ’s Disease Patient-Reported Outcomes Signs and Symptoms (CD-PRO/SS)
Office of Drug Evaluation (ODE) III Division of Gastroenterology and Inborn Error Products (DGIEP) DDT COA Number DDT COA #000034 (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 27, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Couple who met on a Crohn's support Facebook group are engaged
Chloe Meade, 25, and Rhys Thomas, 30, from Wales, connected on social media in 2015 after they both battled severe symptoms of the inflammatory bowel disease. (Source: the Mail online | Health)
Source: the Mail online | Health - September 27, 2019 Category: Consumer Health News Source Type: news

The Association between Inflammatory Bowel Disease and Periodontal Conditions: Is There a Common Bacterial Etiology?
CONCLUSION:A number of studies have showed an association between PD and IBD. Both diseases share genetic and environmental etiological factors. The precise role of intestinal bacteria remains vague. The periodontal microbiota that might be involved in the association of these diseases are Fusobacterium nucleatum, Campylobacter rectus and Campylobacter concisus. Fungal and viral microbiota dysbiosis should also be evaluated as common pathogenic pathways in IBD and periodontal disease. (Source: Dental Technology Blog)
Source: Dental Technology Blog - September 24, 2019 Category: Dentistry Source Type: news

Risk of Crohn's Disease or UC With Anti-TNFa Agents Risk of Crohn's Disease or UC With Anti-TNFa Agents
Is there an increased risk of developing de novo inflammatory bowel disease while under treatment with anti-TNF-alpha for other chronic inflammatory or immune-mediated diseases?Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - September 18, 2019 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

B.C. expands biosimilar drug program to include treatments for Crohn's, colitis
The British Columbia government says it is expanding its substitute drug program to include 1,700 patients with diseases such as Crohn's and colitis. (Source: CBC | Health)
Source: CBC | Health - September 6, 2019 Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

NHS saves £300MILLION in a year by telling doctors to stop giving out expensive branded medications
Hospitals spent £290million on adalimumab - a drug primarily used to treat arthritis but also given to patients with Crohn's disease - in 2018/19. (Source: the Mail online | Health)
Source: the Mail online | Health - August 31, 2019 Category: Consumer Health News Source Type: news

These are the top 25 costliest prescription drugs for Oregon insurers
Humira is the best-selling medicine in the world and a gold mine for drug maker AbbVie, bringing in $4.87 billion in revenue globally in the second quarter. The drug, which treats rheumatoid arthritis and Crohn's disease, costs upwards of $60,000 a year. So it may come as no surprise that Humira is on the list of the 25 most costly drugs for Oregon health insurers in 2018. The combined list is based on the rankings submitted by nine insurance comp anies and takes into account total annual spending,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - August 20, 2019 Category: Biotechnology Authors: Elizabeth Hayes Source Type: news

Children who have Crohn's or colitis 'are 60% more likely to be diagnosed with anxiety'
Researchers at the Karolinska Institutet in Sweden analysed data from 6,400 children, tracking them for an average of nine years. The results were published in JAMA Pediatrics. (Source: the Mail online | Health)
Source: the Mail online | Health - August 19, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Immune system pathway may be key to Crohn's disease treatment
A new study looks at the interaction between a specific protein and a type of receptor. Blocking this specific pathway may help treat Crohn's. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 19, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Internal Spray Developed At Harvard Could Heal Gut Wounds
BOSTON (CBS) – Local researchers have developed a novel approach to help heal wounds “inside” the body. If you get a cut or a scratch on your skin, you can simply cover it with a bandage to help it heal, but there is no such remedy for wounds in the gut because it’s coated with a layer of mucus that prevents bandages from sticking. Now, researchers at the Wyss Institute at Harvard University are using gut bacteria to produce a probiotic hydrogel which could be sprayed onto a wound in the intestine to form a seal – like a spray-on bandage for the gut. This technology could one day be used to tr...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated CBSN Boston Syndicated Local Dr. Mallika Marshall Harvard University Source Type: news

Three-year Effectiveness and Safety of Vedolizumab for IBD Three-year Effectiveness and Safety of Vedolizumab for IBD
This study examined the effectiveness and safety of long-term vedolizumab maintenance therapy in patients with moderate-to-severe active ulcerative colitis and Crohn's disease.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 12, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Adalimumab in tight-control approach cost effective in Crohn's
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - August 1, 2019 Category: Drugs & Pharmacology Source Type: news

Mesenchymal-Stromal-Cell Therapy Effective Long-Term for Crohn's Disease Perianal Fistulas Mesenchymal-Stromal-Cell Therapy Effective Long-Term for Crohn's Disease Perianal Fistulas
Most patients with Crohn's disease whose perianal fistulas close after allogeneic bone marrow-derived mesenchymal stromal cell (bmMSC) therapy remain fistula-free four years later, researchers from the Netherlands report.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 30, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Etanercept Tx for Autoimmune Disease May Up Risk for IBD
MONDAY, July 15, 2019 -- Patients with autoimmune diseases have an increased risk for being diagnosed with Crohn disease (CD) or ulcerative colitis (UC) while under treatment with etanercept, according to a study published online July 2 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 15, 2019 Category: Pharmaceuticals Source Type: news

Gut virus 'older than humanity' could be useful for Crohn's and diabetes medicine
The virus, nicknamed crAssphage, doesn't cause disease but can attack bacteria. Researchers at San Diego State University said it likely evolved over millions of years to become normal in the gut. (Source: the Mail online | Health)
Source: the Mail online | Health - July 10, 2019 Category: Consumer Health News Source Type: news

Optimal Biopsy Location for Assessments in Crohn's Disease Optimal Biopsy Location for Assessments in Crohn's Disease
Determining the optimal location for biopsy procurement in Crohn's disease may lead to a more accurate assessment of disease activity.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 8, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: Could a plant based diet be the answer to Crohn's disease?
Following a plant based diet helped one man with Crohn's disease achieve complete remission after a year of standard treatment had failed to do so. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 27, 2019 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Proactive Drug Monitoring Improves Outcomes in Kids With Crohn ’ s Proactive Drug Monitoring Improves Outcomes in Kids With Crohn ’ s
Proactive therapeutic-drug monitoring (TDM) in children with Crohn's disease on adalimumab reduces clinical exacerbations compared to reactive TDM, a randomized controlled trial shows.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 26, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Gut microbe provokes release of inflammatory substance
Researchers discovered how a gut microbe linked to Crohn ’s disease may stimulate immune cells to trigger inflammation. (Source: NIH Research Matters)
Source: NIH Research Matters - June 25, 2019 Category: Research Source Type: news

Crohn's patient REVERSES his painful condition by going vegan
Doctors who treated the man in Missouri believe the high-fibre diet could be beneficial for people with Crohn's. But other experts warn against such drastic measures. (Source: the Mail online | Health)
Source: the Mail online | Health - June 24, 2019 Category: Consumer Health News Source Type: news