AI accurately predicts effects of genetic mutations in biological dark matter
(Simons Foundation) A new machine learning framework, dubbed ExPecto, can predict the effects of genetic mutations in the so-called 'dark matter' regions of the human genome. ExPecto pinpoints how specific mutations can disrupt the way genes express throughout your body. Using the method, its creators computed the genetic ramifications of more than 140 million mutations in different tissues. The researchers also precisely pinpointed mutations potentially responsible for increasing the risk of several immune-related diseases, including Crohn's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2018 Category: International Medicine & Public Health Source Type: news

Acetaminophen, NSAIDs and Risk of IBD Exacerbation Acetaminophen, NSAIDs and Risk of IBD Exacerbation
Does the use of NSAIDs or COX-2 inhibitors exacerbate Crohn's disease or ulcerative colitis?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 10, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Gender-bending chemical may cause inflammatory bowel disease
Researchers from Texas A&M University found that exposure to bisphenol A (BPA) causes the same inflammation and gut bacteria changes in mice that occur in Crohn's and ulcerative colitis patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 6, 2018 Category: Consumer Health News Source Type: news

Exposure to a gender-bending chemical found in bank notes may cause inflammatory bowel disease
Researchers from Texas A&M University found that exposure to bisphenol A (BPA) causes the same inflammation and gut bacteria changes in mice that occur in Crohn's and ulcerative colitis patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 6, 2018 Category: Consumer Health News Source Type: news

Medical News Today: Could treating these immune cells cure IBD?
By identifying a distinct group of CD4 T cells that create and perpetuate intestinal inflammation, scientists could be on track to finding a cure for IBD. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 28, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Immune cells that create and sustain chronic inflammatory bowel disease identified
(University of Alabama at Birmingham) In preclinical experiments, Laurie Harrington and colleagues have discovered a subset of immune cells that create and sustain chronic inflammatory bowel disease. These cells could become potential therapeutic targets to ameliorate or cure Crohn's disease and ulcerative colitis. Furthermore, if this subset of CD4 T cells plays a similar role in other autoimmune diseases, such as Type 1 diabetes or rheumatoid arthritis, they could also be targets for therapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 26, 2018 Category: International Medicine & Public Health Source Type: news

Tattoo health warning for people with weakened immune systems
A woman with cystic fibrosis and lung transplants suffered chronic pain for three years after she had a tattoo on her thighGetting a tattoo if you have a weakened immune system could put you at risk of complications, doctors have warned. The caution comes after a woman with cystic fibrosis and lung transplants developed thigh and knee pain after having body art inked on her leg.Doctors say those taking immunosuppressant drugs should take precautions if considering body art. These medicines are often given after an organ transplant or to treat autoimmune conditions such as Crohn ’s disease, lupus or rheumatoid arthrit...
Source: Guardian Unlimited Science - June 18, 2018 Category: Science Authors: Nicola Davis Tags: Tattoos Medical research Immunology Biochemistry and molecular biology Health Cystic fibrosis Diabetes Source Type: news

PET tracer may aid diagnosis of inflammatory bowel disease
Researchers have used a new PET tracer to identify areas of inflammation in...Read more on AuntMinnie.comRelated Reading: Immuno-PET tracer offers hope for early cancer treatment Novel PET tracer could help assess arthritis PET/CT enhances detection of inflammatory bowel disease Imaging modalities prove crucial for an accurate differential diagnosis of inflammatory conditions FDG-PET/CT may help quantify Crohn's disease severity (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - June 4, 2018 Category: Radiology Source Type: news

Hidradenitis Suppurativa Tied to Increased Risk of Crohn's Disease Hidradenitis Suppurativa Tied to Increased Risk of Crohn's Disease
Patients with hidradenitis suppurativa (HS), a skin disorder characterized by painful nodules and abscesses, may be at increased risk for Crohn's disease (CD), and those with GI symptoms should be seen by a gastroenterologist, researchers in New York say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

American Cancer Society Advises Colon Screenings Should Begin at 45, Not 50
NEW YORK (AP) — New guidelines released Wednesday recommend U.S. adults start colon cancer screening earlier, at age 45 instead of 50. The American Cancer Society's advice puts it out of sync with guidelines from an influential government advisory group, which kept the age at 50 in an update two years ago. Cancer society officials acknowledge the shift to 45 could cause confusion for doctors and patients but felt strongly that they needed to act now. The advocacy group was influenced by its study, published last year, that found rising rates of colon cancer and deaths in people younger than 50. Experts aren't sure wh...
Source: JEMS Patient Care - May 31, 2018 Category: Emergency Medicine Authors: Mike Stobbe, Associated Press Tags: Patient Care News Source Type: news

American Cancer Society Advises Colon Screenings Should Begin at 45, Not 50
NEW YORK (AP) — New guidelines released Wednesday recommend U.S. adults start colon cancer screening earlier, at age 45 instead of 50. The American Cancer Society's advice puts it out of sync with guidelines from an influential government advisory group, which kept the age at 50 in an update two years ago. Cancer society officials acknowledge the shift to 45 could cause confusion for doctors and patients but felt strongly that they needed to act now. The advocacy group was influenced by its study, published last year, that found rising rates of colon cancer and deaths in people younger than 50. Experts aren't sure wh...
Source: JEMS: Journal of Emergency Medical Services News - May 31, 2018 Category: Emergency Medicine Authors: Mike Stobbe, Associated Press Tags: Patient Care News Source Type: news

American Cancer Society Advises Colon Screenings Should Begin at 45, Not 50
NEW YORK (AP) — New guidelines released Wednesday recommend U.S. adults start colon cancer screening earlier, at age 45 instead of 50. The American Cancer Society's advice puts it out of sync with guidelines from an influential government advisory group, which kept the age at 50 in an update two years ago. Cancer society officials acknowledge the shift to 45 could cause confusion for doctors and patients but felt strongly that they needed to act now. The advocacy group was influenced by its study, published last year, that found rising rates of colon cancer and deaths in people younger than 50. Experts aren't sure wh...
Source: JEMS Patient Care - May 31, 2018 Category: Emergency Medicine Authors: Mike Stobbe, Associated Press Tags: Patient Care News Source Type: news

American Cancer Society Advises Colon Screenings Should Begin at 45, Not 50
NEW YORK (AP) — New guidelines released Wednesday recommend U.S. adults start colon cancer screening earlier, at age 45 instead of 50. The American Cancer Society's advice puts it out of sync with guidelines from an influential government advisory group, which kept the age at 50 in an update two years ago. Cancer society officials acknowledge the shift to 45 could cause confusion for doctors and patients but felt strongly that they needed to act now. The advocacy group was influenced by its study, published last year, that found rising rates of colon cancer and deaths in people younger than 50. Experts aren't sure wh...
Source: JEMS: Journal of Emergency Medical Services News - May 31, 2018 Category: Emergency Medicine Authors: Mike Stobbe, Associated Press Tags: Patient Care News Source Type: news

Intestinal Paracoccidioidomycosis Resembling Crohn's Disease Intestinal Paracoccidioidomycosis Resembling Crohn's Disease
In this case, a fungal disease convincingly mimicked clinical manifestations and colonoscopic and histological findings of Crohn's disease.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 30, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Medical News Today: Inflammatory bowel disease may raise Parkinson's risk
Having IBD is tied to a 22 percent higher risk of Parkinson's disease, according to a nationwide Danish population study that covered nearly 40 years. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 22, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Inflammatory bowel disease may raise Parkinson's risk
Having IBD is tied to a 22 percent higher risk of Parkinson's disease, according to a nationwide Danish population study that covered nearly 40 years. (Source: Parkinson's Disease News From Medical News Today)
Source: Parkinson's Disease News From Medical News Today - May 22, 2018 Category: Neurology Tags: Crohn's / IBD Source Type: news

Medical News Today: E. coli toxin linked with inflammatory bowel disease
Researchers have accidentally discovered a surprising link between microcin B17, a toxin produced by E. coli, and inflammatory bowel disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 19, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Frank Russomano Elected to National Board of Trustees of Crohn ’s & ...
President and CEO of US HealthConnect Inc. leverages 25 years of experience in healthcare education and personal family experience with Crohn’s Disease to help the Foundation meet its mission(PRWeb May 17, 2018)Read the full story at http://www.prweb.com/releases/2018/05/prweb15498184.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - May 17, 2018 Category: Pharmaceuticals Source Type: news

Frank Russomano Elected to National Board of Trustees of Crohn ’s & ...
President and CEO of US HealthConnect Inc. leverages 25 years of experience in healthcare education and personal family experience with Crohn’s Disease to help the Foundation meet its mission(PRWeb May 17, 2018)Read the full story at https://www.prweb.com/releases/2018/05/prweb15498184.htm (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - May 17, 2018 Category: Pharmaceuticals Source Type: news

Is Verily Making a Blood Collection Device Involving & #039;Exploding & #039; Micro-Needles?
According to a CNBC report, Verily is developing a wearable blood collection device using micro-needles and magnets in an effort to make blood collection less painful and obnoxious for patients who need to be frequently monitored. The news report cites unnamed sources who said the concept has already been tested with a watch, but the project is still years away from reaching the market. Apparently, the device would include micro-needles that would "explode" into the user's skin, then be retracted by magnets for future use. The report noted that the long-term project company faces significant scientific, technical...
Source: MDDI - May 16, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: R & D Source Type: news

Science-backed eating tips for those with inflammatory bowel disease
(Natural News) If you suffer from IBS, your diet can help treat your condition. Researchers have recently identified some science-backed eating tips for relieving or treating inflammatory bowel disease. Inflammatory bowel diseases, such as colitis and Crohn’s disease, are disorders that cause chronic inflammation in the digestive tract. The signs and symptoms that are common to... (Source: NaturalNews.com)
Source: NaturalNews.com - May 15, 2018 Category: Consumer Health News Source Type: news

Medical News Today: What causes undigested food to appear in stool?
Certain foods, including high-fiber foods and sweetcorn, are more difficult to digest than others. It is normal for a person to notice undigested bits of these foods in their stool. If undigested food in the stool occurs with other symptoms, including diarrhea, they may have a medical condition, such as Crohn ’s or IBS. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 9, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Health Tip: Manage Symptoms of Crohn's Disease
-- Crohn's disease is a chronic condition that causes inflammationand irritation of the digestive tract. It affects more than 500,000 people in the United States, the National Institute of Diabetes and Digestive and Kidney Diseases says. People... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 25, 2018 Category: General Medicine Source Type: news

Health Tip: Manage Symptoms of Crohn's Disease
Title: Health Tip: Manage Symptoms of Crohn's DiseaseCategory: Health NewsCreated: 4/25/2018 12:00:00 AMLast Editorial Review: 4/25/2018 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - April 25, 2018 Category: Nutrition Source Type: news

Medical News Today: What to eat and avoid on a low-fiber diet
Fiber is an essential part of a healthful diet, but some people may benefit from eating less fiber, especially if they have irritable bowel disease (IBD) or have had a recent bowel surgery. In this article, learn which foods to eat and to avoid when on a low-fiber diet, as well as tips on how to get adequate nutrients. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 20, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Bioelectronic Medicine: Targeting Inflammatory Disease with Electricity
We presented positive initial results in Crohn’s disease at the 2016 United European Gastroenterology meeting: six of the eight patients had seen a substantial reduction in their disease activity index scores, and three were in remission from the disease. As SetPoint looks ahead, several chronic disease areas are emerging as key bioelectronic medicine therapy targets, and our company is exploring a number of these. One of our preclinical programs explores bioelectronic medicine’s potential role as a treatment for MS.   New Target: Multiple Sclerosis In late 2017, SetPoint presented positive data from a s...
Source: Mass Device - April 17, 2018 Category: Medical Devices Authors: Anthony Arnold Tags: Bioelectronic Medicine Clinical Trials Neuromodulation/Neurostimulation SetPoint Medical Sponsored Content Source Type: news

Vedolizumab-treated CD Patients Undergoing Abdominal Surgery Vedolizumab-treated CD Patients Undergoing Abdominal Surgery
Biologic therapies are known to increase infection risk. How does vedolizumab impact the incidence of postoperative infectious complications among Crohn's disease patients?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 17, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Long-term Efficacy, Safety of Ustekinumab in Refractory CD Long-term Efficacy, Safety of Ustekinumab in Refractory CD
This study evaluated the long-term efficacy and safety of ustekinumab in anti-TNF refractory Crohn's disease patients.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 12, 2018 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

You Asked: What Is Inflammation, And Why Should I Care About It?
Your body can heal itself, which is pretty miraculous when you sit back and think about it. If you suffer a cut or infection—or if a disease, allergen or virus finds its way into you—your immune system reacts by sending specialized white blood cells to the affected area. These white blood cells can repair damage, stop the spread of infection or illness and in some cases eradicate the intruder. This whole response is called inflammation. “Inflammation is an activation of cells and cell-derived components that have the job of fighting invasions, and in some cases just sponging up or clearing out damaged cel...
Source: TIME: Health - April 11, 2018 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthytime medicine Source Type: news

Sickeningly sweet: Artificial sweeteners worsen gut inflammation, intensify symptoms of Crohn's disease
(Natural News) The lure of a calorie-free sweetener is hard to beat; after all, who doesn’t want to have their cake and eat it, too? The promise of zero-calorie beverages and lower-calorie baked goods that come along with sugar substitutes are often convincing enough on their own for the calorie-conscious among us. But studies have... (Source: NaturalNews.com)
Source: NaturalNews.com - April 11, 2018 Category: Consumer Health News Source Type: news

Exclusive Enteral Nutrition for Pediatric Crohn's Varies Significantly Worldwide Exclusive Enteral Nutrition for Pediatric Crohn's Varies Significantly Worldwide
Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - April 6, 2018 Category: Intensive Care Tags: Pediatrics News Source Type: news

Analysis challenges link between pain medications and inflammatory bowel disease
(Wiley) Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 5, 2018 Category: International Medicine & Public Health Source Type: news

Better Outcomes After End-to-End Ileocecal Anastomosis in Crohn's Better Outcomes After End-to-End Ileocecal Anastomosis in Crohn's
Following intestinal resection in Crohn's disease, end-to-end ileocecal anastomosis (ETEA) is associated with better outcomes than is side-to-side anastomosis (STSA), according to a registry study.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 2, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Dynamo reveals Crohn’s struggle - what are the symptoms? Dr Zoe says look out for this
DYNAMO, the TV magician, opened up about his struggle with Crohn ’s disease this week. What are the symptoms of the condition? Dr Zoe Williams revealed what to look out for on This Morning and how best to treat it. (Source: Daily Express - Health)
Source: Daily Express - Health - March 29, 2018 Category: Consumer Health News Source Type: news

Magician Dynamo opens up about Crohn's struggle
Images posted to social media by the magician have prompted others to share their stories of Crohn's disease. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 27, 2018 Category: Consumer Health News Source Type: news

Dynamo Crohn's selfie prompts others to share
Images posted to social media by the magician have prompted others to share their stories of Crohn's disease. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - March 27, 2018 Category: Consumer Health News Source Type: news

Could This Device Replace Drugs for Rheumatoid Arthritis Treatment?
SetPoint Medical has launched a pilot trial to assess the safety and efficacy of a bioelectronics device in patients, who are suffering from rheumatoid arthritis and who are not adequately responsive to multiple biologic agents. The study will enroll a total of 15 subjects, aged 22 to 75, across seven U.S. investigational centers. Valencia, CA-based SetPoint's approach toward treating RA is designed to supplement the body's natural inflammatory reflex by providing "built-in" therapy and is intended to improve safety compared with drugs or biologic solutions. Currently pharmaceutical options are used to treat...
Source: MDDI - March 26, 2018 Category: Medical Devices Authors: Omar Ford Tags: Digital Health Implants Source Type: news

Fecal Microbiota Profile Predicts Ustekinumab Response in Crohn's Fecal Microbiota Profile Predicts Ustekinumab Response in Crohn's
Data on patients ’ fecal microbiota can be used to predict their response to ustekinumab therapy for Crohn's disease, researchers report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - March 26, 2018 Category: Pathology Tags: Gastroenterology News Source Type: news

EMA Committee Backs Remicade Biosimilar Zessly EMA Committee Backs Remicade Biosimilar Zessly
The committee favors marketing the infliximab biosimilar product Zessly for treatment of rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriatic arthritis, and psoriasis.International Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 23, 2018 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

Ask Is Crohn ’s Disease Genetic or Hereditary
Is Crohn ’s Disease Genetic or Hereditary? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - March 19, 2018 Category: General Medicine Source Type: news

Ask What Not to Eat When You Have Crohns Disease
What Not to Eat When You Have Crohn ’s Disease (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - March 19, 2018 Category: General Medicine Source Type: news

Splenda may intensify Crohn's symptoms, study finds
Splenda, an artificial sweetener, could intensify the symptoms of Crohn's disease in people who have it, according to a study with mice. (Source: Health News - UPI.com)
Source: Health News - UPI.com - March 16, 2018 Category: Consumer Health News Source Type: news

Artificial sweetener Splenda could intensify symptoms in those with Crohn's disease
(Case Western Reserve University) In a study that has implications for humans with inflammatory diseases, researchers have found that, given over a six-week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's disease, but had no substantive effect on those without the condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 15, 2018 Category: International Medicine & Public Health Source Type: news

Understanding how Crohn ’s Disease treatments affect children’s gut microbiome
Study finds different Crohn ’s disease treatments have varying effects on the gut microbiomes of children and teens. This may help inform treatment approaches. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Origins of Gut Inflammation Found in Specific Cell Type
Paneth cells in the intestine are linked to development of inflammation similar to Crohn ’s disease in mice, which could lead to new bowel disease treatments. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news

Study: Doctors Who Prescribe More Opioids Make More Money
This study suggests that conflicts of interest with the pharmaceutical industry may influence oncologists in high-stakes treatment decisions for patients with cancer,” the authors concluded. Some studies have looked at whether the amount of money a doctor receives makes a difference. Studies by researchers at Yale University, the George Washington University Milken Institute of Public Health and Harvard Medical School have all found that the more money physicians are paid by pharmaceutical companies, the more likely they are to prescribe certain drugs. Dr. Patrice Harris, a spokeswoman for the American Medical Associ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 12, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Local TV opioid crisis opioids Source Type: news

PANTS: Predicting Nonresponse to Anti-TNF in Crohn's Disease PANTS: Predicting Nonresponse to Anti-TNF in Crohn's Disease
The largest prospective study of tumor necrosis factor (TNF) inhibitor therapy in Crohn's disease estimates drug response and confirms the role that pharmacokinetics and immunogenicity play.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 5, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Childhood Crohn's Progression Halted by Biologics (CME/CE)
(MedPage Today) -- Need for surgery still high in first years after diagnosis (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - March 2, 2018 Category: Gastroenterology Source Type: news

Vedolizumab Relieves Refractory Crohn's Disease Vedolizumab Relieves Refractory Crohn's Disease
The monoclonal antibody helps some patients with Crohn's disease, according to the VERSIFY study, which builds on findings from the GEMINI 2 and 3 trials.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 1, 2018 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Medical News Today: Inflammatory bowel disease may raise heart attack risk
An analysis of more than 17.5 million patients' medical records reveals that having IBD raises heart attack risk independently of other risk factors. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 1, 2018 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news