What Does Crohn's Pain Feel Like
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - April 16, 2021 Category: General Medicine Source Type: news

90-Day Specific Readmission for Clostridium difficile Infection After Hospitalization With an Inflammatory Bowel Disease Flare: Outcomes and Risk Factors, Inflammatory Bowel Diseases
Conclusions The 90-day CDI-specific readmission rate after the index admission of IBD flares was 0.1%. We found risk factors for CDI-associated readmissions such as history of Parkinson's disease, prior CDI, HIV-positive status, and alcohol abuse disorder. Finally, our study also revealed a high health care cost, charges, and burden. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 15, 2021 Category: Consumer Health News Source Type: news

FDA Approves Xolair (omalizumab) Prefilled Syringe for Self-Injection Across All Indications
●  Xolair for self-injection offers healthcare providers and appropriate patients another administration option for more flexibility in managing their treatmentBasel, 13 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications.1 Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic ...
Source: Roche Media News - April 13, 2021 Category: Pharmaceuticals Source Type: news

FDA Approves Xolair (omalizumab) Prefilled Syringe for Self-Injection Across All Indications
●  Xolair for self-injection offers healthcare providers and appropriate patients another administration option for more flexibility in managing their treatmentBasel, 13 April 2020 - Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced that the U.S. Food and Drug Administration (FDA) has approved the company ’s supplemental Biologics License Application for Xolair® (omalizumab) prefilled syringe for self-injection across all approved U.S. indications.1 Xolair is the only FDA-approved biologic designed to target and block immunoglobulin E (IgE) for the treatment of moderate to severe persistent allergic ...
Source: Roche Investor Update - April 13, 2021 Category: Pharmaceuticals Source Type: news

What Are The Types of Crohn's Disease
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - April 12, 2021 Category: General Medicine Source Type: news

Ben-Gurion University researchers developing probiotic yogurt-based drugs
(American Associates, Ben-Gurion University of the Negev) " This is the first demonstration that virulence of human pathogenic bacteria can be mitigated by molecules secreted in probiotic milk products, such as yogurt or kefir, " said BGU Prof. Jelinek. " Our research illuminates the mechanism by which milk fermented probiotics can protect against pathogenic infections and aid the immune system. We look forward to administering these drug candidates to patients who are experiencing a cytokine storm due to COVID-19 infection, or people suffering from acute inflammatory bowel pathologies, such as Crohn's disea...
Source: EurekAlert! - Infectious and Emerging Diseases - April 12, 2021 Category: Infectious Diseases Source Type: news

Crohn's disease may be caused by immune signaling failure
(Scripps Research Institute) Scientists find that T cells in the small intestine prevent bile acid-driven stress and inflammation. The work highlights a completely new direction in Crohn's disease research, and potentially, its treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 7, 2021 Category: International Medicine & Public Health Source Type: news

Possible trigger for Crohn's disease identified
(McMaster University) AIEC bacteria grow in a biofilm that coats cells lining the intestinal wall, protecting them from both the immune system and antibiotics. In this research, the team identified a critical protein structure on the surface of the bacteria that allow them to grow in biofilms. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 1, 2021 Category: International Medicine & Public Health Source Type: news

Inflammatory Bowel Disease May Up Risk for Psychiatric Disorders
TUESDAY, March 30, 2021 -- Adult-onset inflammatory bowel disease (IBD) is associated with an increased risk for psychiatric disorders and suicide attempts, according to a study published online Feb. 26 in the Journal of Crohn's and Colitis. Jonas... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 30, 2021 Category: Pharmaceuticals Source Type: news

What Happens if Crohn ’s Is Left Untreated?
Title: What Happens if Crohn ’s Is Left Untreated?Category: Diseases and ConditionsCreated: 3/30/2021 12:00:00 AMLast Editorial Review: 3/30/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 30, 2021 Category: Nutrition Source Type: news

< a href= " /news-events/nih-research-matters/fungi-may-impair-wound-healing-crohns-disease " > Fungi may impair wound healing in Crohn ’s disease < /a >
A fungus called Debaryomyces hansenii impaired gut wound healing in mice, and was also found in damaged gut tissue in people with Crohn ’s disease. (Source: NIH Research Matters from the National Institutes of Health (NIH))
Source: NIH Research Matters from the National Institutes of Health (NIH) - March 30, 2021 Category: Consumer Health News Source Type: news

What Are Indications for a Ileostomy?
Discussion There are three types of inflammatory bowel disease (IBD): Crohn’s disease (CD) – can affect entire gastrointestinal tract but often is discontinuous (i.e., has skipped areas), has transmural inflammation and disease, has granulomas Ulcerative colitis (UC) – affects the colon, is continuous (i.e., has no skipped areas) and has superficial mucosal ulcerations Unclassified IBD – has chronic colitis but not specific features of CD or UC The specific pathogenesis appears to be multifactorial with having a genetic predisposition (1.6 – 30% risk of developing UC if patient has first deg...
Source: PediatricEducation.org - March 29, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation
(University of Alabama at Birmingham) Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice. The study will aid the understanding of, and future research into, this immune disorder, which includes Crohn's disease and ulcerative colitis. About 1.6 million Americans have inflammatory bowel disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2021 Category: International Medicine & Public Health Source Type: news

Antibody injections could become more affordable with new production method
(Penn State) Antibody injections are a highly desirable treatment for people with chronic diseases such as cancer, psoriasis, Crohn's disease and arthritis. And recently, antibodies have been in the news as a promising treatment for severe cases of COVID-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2021 Category: International Medicine & Public Health Source Type: news

Common inflammatory bowel disease treatment linked to reduced COVID-19 antibody response
(University of Exeter) The findings arose from the CLARITY study, which recruited 6,935 patients with Crohn's disease and ulcerative colitis from 92 UK hospitals between September and December 2020. It found that fewer than half of people with IBD who were treated with infliximab had detectable antibodies after SARS-CoV-2 infection, the coronavirus that causes COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 22, 2021 Category: Infectious Diseases Source Type: news

Could a Yeast Found in Cheese Be Key to Easing Crohn's Disease?
WEDNESDAY, March 17, 2021 -- A new tissue infection has been identified in Crohn's disease patients, and researchers say their finding could ultimately lead to better treatment of the common inflammatory bowel disease. Areas of unhealed wounds in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 17, 2021 Category: General Medicine Source Type: news

Could a Yeast Found in Cheese Be Key to Easing Crohn's Disease?
Title: Could a Yeast Found in Cheese Be Key to Easing Crohn's Disease?Category: Health NewsCreated: 3/17/2021 12:00:00 AMLast Editorial Review: 3/17/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 17, 2021 Category: Nutrition Source Type: news

Mayo Clinic Q & amp;A podcast: The increasing prevalence of inflammatory bowel disease
Inflammatory bowel disease is common, and it is becoming more common in many populations. Dr. William Faubion Jr., a Mayo Clinic gastroenterologist, says inflammatory bowel disease is an umbrella term that covers Crohn's disease and ulcerative colitis, and that inflammatory bowel disease is an emerging public health problem. "The most recent estimates would be that, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 16, 2021 Category: Databases & Libraries Source Type: news

Swallowable Capsule-Camera Instead of Endoscopy: Now in Patients Swallowable Capsule-Camera Instead of Endoscopy: Now in Patients
Now being tested in patients in England, a swallowable capsule device transmits images of the inside of the gut that can reveal cancer and conditions such as Crohn's disease.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Swallowable Capsule-Camera Instead of Endoscopy for Use at Home Swallowable Capsule-Camera Instead of Endoscopy for Use at Home
Now being tested in patients in England, a swallowable capsule device transmits images of the inside of the gut that can reveal cancer and conditions such as Crohn's disease.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Debaryomyces is enriched in Crohns disease intestinal tissue and impairs healing in mice
Alterations of the mycobiota composition associated with Crohn’s disease (CD) are challenging to link to defining elements of pathophysiology, such as poor injury repair. Using culture-dependent and -independent methods, we discovered that Debaryomyces hansenii preferentially localized to and was abundant within incompletely healed intestinal wounds of mice and inflamed mucosal tissues of CD human subjects. D. hansenii cultures from injured mice and inflamed CD tissues impaired colonic healing when introduced into injured conventionally raised or gnotobiotic mice. We reisolated D. hansenii from injured areas of these...
Source: ScienceNOW - March 11, 2021 Category: Science Authors: Jain, U., Ver Heul, A. M., Xiong, S., Gregory, M. H., Demers, E. G., Kern, J. T., Lai, C.-W., Muegge, B. D., Barisas, D. A. G., Leal-Ekman, J. S., Deepak, P., Ciorba, M. A., Liu, T.-C., Hogan, D. A., Debbas, P., Braun, J., McGovern, D. P. B., Underhill, D Tags: Medicine, Diseases, Microbiology reports Source Type: news

Hyperbaric Oxygen for Perianal Fistulas in Crohn's Disease Hyperbaric Oxygen for Perianal Fistulas in Crohn's Disease
This study assessed the efficacy, safety and feasibility of hyperbaric oxygen therapy in Crohn's disease patients with therapy-refractory perianal fistulas.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 8, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Immune-mediated Diseases and Risk of IBD Immune-mediated Diseases and Risk of IBD
Are individuals with other immune-mediated diseases at greater risk of developing ulcerative colitis or Crohn's disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Adherent-Invasive E. Coli Metabolism Drives Inflammation in Crohn's Disease Adherent-Invasive E. Coli Metabolism Drives Inflammation in Crohn's Disease
Researchers have identified the process by which adherent-invasive Escherichia coli (AIEC) bacteria drive inflammation in Crohn's disease.Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 18, 2021 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New potential therapy for Crohn's disease in children
(Ann& Robert H. Lurie Children's Hospital of Chicago) Scientists from the Stanley Manne Children's Research Institute at Ann& Robert H. Lurie Children's Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2021 Category: International Medicine & Public Health Source Type: news

Avexegen Therapeutics Receives a $2.94M NIH Grant to Advance Treatment for Inflammatory Bowel Disease
SAN FRANCISCO, Feb. 15, 2021 -- (Healthcare Sales & Marketing Network) -- Avexegen Therapeutics Inc. today announced that it has received a Phase 2 award of $2.94 million under the National Institutes of Health's Small Business Innovation Research Program... Biopharmaceuticals, Gastroenterology Avexegen Therapeutics, inflammatory bowel disease, Crohn's Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 15, 2021 Category: Pharmaceuticals Source Type: news

Study identifies 'Achilles heel' of bacteria linked to Crohn's disease
(Weill Cornell Medicine) The discovery of an " Achilles heel " in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2021 Category: International Medicine & Public Health Source Type: news

Allegretti Wins Sherman Emerging Leader Prize
Jessica Allegretti, MD, MPH, director of the Fecal Transplant Program for the Division of Gastroenterology and director of Clinical Trials for the Crohn's and Colitis Center, won the $25,000 Sherman Emerging Leader Prize for her commitment to pushing (Source: BWH News)
Source: BWH News - February 1, 2021 Category: Hospital Management Source Type: news

Crohn Disease, Comorbidities Up Risk for Severe Pneumococcal Disease
Receipt of PCV13 alone or in combination with PPSV23 predicts fivefold reduced risk for SPD compared with no vaccination (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - January 29, 2021 Category: Respiratory Medicine Tags: Family Medicine, Gastroenterology, Infections, Internal Medicine, Pharmacy, Pulmonology, Journal, Source Type: news

Crohn Disease, Comorbidities Up Risk for Severe Pneumococcal Disease
THURSDAY, Jan. 28, 2021 -- For veterans with inflammatory bowel disease (IBD), the risk for severe pneumococcal disease (SPD) is increased with Crohn disease and with more comorbidities, and pneumococcal vaccination is associated with a reduced risk... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 28, 2021 Category: Pharmaceuticals Source Type: news

What Happens When You Stop Taking Crohn ’s Meds?
When you have Crohn’s disease, you probably have to take medications long term. But can you stop if you’re feeling better? Here’s what you need to know. (Source: WebMD Health)
Source: WebMD Health - January 27, 2021 Category: Consumer Health News Source Type: news

Tips to Make Travel With Crohn ’s Disease Easier
Think you can’t travel because you have Crohn’s disease? Think again. Follow these tips to help make traveling with Crohn’s disease easier. (Source: WebMD Health)
Source: WebMD Health - January 26, 2021 Category: Consumer Health News Source Type: news

Crohn ’s Disease: Hacks for Life With a Colostomy Bag
People share their advice on how to make day-to-day life with a colostomy bag more comfortable. (Source: WebMD Health)
Source: WebMD Health - January 25, 2021 Category: Consumer Health News Source Type: news

Can Kombucha Help With Crohn ’s Disease?
Some people with Crohn’s disease try kombucha to prevent or ease symptoms. Kombucha is made of tea and is high in probiotics. But will it help or hurt? (Source: WebMD Health)
Source: WebMD Health - January 25, 2021 Category: Consumer Health News Source Type: news

Best Exercises for Crohn ’s Disease
Should you work out if you have Crohn’s? Yes. Find out what kind of activity is best for people with this chronic condition. (Source: WebMD Health)
Source: WebMD Health - January 25, 2021 Category: Consumer Health News Source Type: news

My Life With Crohn's
What’s it like to live with Crohn’s disease? One woman shares her story. (Source: WebMD Health)
Source: WebMD Health - January 25, 2021 Category: Consumer Health News Source Type: news

New partnership announced to develop first prognostic tests for pediatric Crohn's disease
(Crohn's& Colitis Foundation of America) The Crohn's& Colitis Foundation has entered into a partnership with LifeArc to potentially develop the first clinical lab test to predict disease course in pediatric patients with Crohn's disease and response to treatment. A prognostic test which could accurately predict which children will develop complications and identify patients most likely to benefit from anti-TNF therapy would help clinicians make effective early treatment decisions to improve outcomes. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 25, 2021 Category: International Medicine & Public Health Source Type: news

Can Apps Help People With Crohn ’s?
An app may help you manage your Crohn’s disease, but there are things to keep in mind. Learn about the pros and cons of Crohn’s apps and how to choose one that’s right for you. (Source: WebMD Health)
Source: WebMD Health - January 22, 2021 Category: Consumer Health News Source Type: news

Device may predict inflammatory bowel flares using human sweat
A new wearable device may help people with inflammatory bowel disease, more quickly predict when flare-ups will occur, a study presented Thursday during the Crohn's& Colitis Congress found. (Source: Health News - UPI.com)
Source: Health News - UPI.com - January 21, 2021 Category: Consumer Health News Source Type: news

Study reveals new details about how bacterial toxins cause life-threatening colitis
FINDINGSResearch led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying C. difficile toxin A, one of two toxins released by the bacterium, the researchers produced two key findings.They pinpointed which part of the toxic protein can permeate cell membranes to gain entry to cellular structures called endosomes, demonstrating that even fragments of the protein that contain that key segment are capable of accessing endosomes.In addition, they revealed how the toxin m...
Source: UCLA Newsroom: Health Sciences - January 8, 2021 Category: Universities & Medical Training Source Type: news

Pandemic leaves chronically ill without critical access to washrooms
Mapping the nearest washrooms before leaving home is routine for Remo Testini. For 14 years, he’s been living with Crohn's disease — a chronic inflammatory bowel condition that can lead to severe abdominal pain and a sudden urgent need to use a restroom, among other issues. (Source: CBC | Health)
Source: CBC | Health - December 28, 2020 Category: Consumer Health News Tags: News/Canada/British Columbia Source Type: news

Her Stomach Hurt Unbearably. Her Doctors Were Baffled.
Then she remembered a story from her mother. (Source: NYT Health)
Source: NYT Health - December 28, 2020 Category: Consumer Health News Authors: Lisa Sanders, M.D. Tags: Crohn ' s Disease Digestive Tract Genetics and Heredity Medicine and Health Source Type: news

Potential preventative treatment demonstrated for Crohn's disease
(University of Alabama at Birmingham) A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 21, 2020 Category: Biology Source Type: news

Can Marijuana or CBD Help With My Crohn's Disease?
There’s a little evidence that cannabis may help with some symptoms of Crohn’s, including improving appetite and sleep, but there's a lot to consider first before you try it. Learn more. (Source: WebMD Health)
Source: WebMD Health - December 18, 2020 Category: Consumer Health News Source Type: news

How Alcohol Affects Crohn's Disease and the Medicines You Take to Treat It
Is it safe to have a drink if you have Crohn's disease? Learn how alcohol affects Crohn's disease and the medicines you take to treat it. (Source: WebMD Health)
Source: WebMD Health - December 18, 2020 Category: Consumer Health News Source Type: news

Join us virtually: 2021 Crohn's & Colitis Congress ®
(American Gastroenterological Association) Media are invited to register for the first virtual Crohn's& Colitis Congress, taking place Jan. 21-24, 2021, and learn about the latest trends and research in inflammatory bowel disease (IBD) patient care. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 18, 2020 Category: International Medicine & Public Health Source Type: news

Crohn ’s Disease: Can Supplements Help?
Which supplements help with Crohn’s disease? Do I need to take supplements? Which vitamins and minerals should I take? Learn which supplements your doctor may recommend for Crohn’s disease. (Source: WebMD Health)
Source: WebMD Health - December 17, 2020 Category: Consumer Health News Source Type: news

New Clues to Crohn's Disease in Kids
Title: New Clues to Crohn's Disease in KidsCategory: Health NewsCreated: 12/14/2020 12:00:00 AMLast Editorial Review: 12/15/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - December 15, 2020 Category: Nutrition Source Type: news

New Clues to Crohn's Disease in Kids
MONDAY, Dec. 14, 2020 -- Important clues about Crohn's disease in children have emerged in new research. Scientists analyzed gene expression in individual cells in the inner lining (epithelium) of the intestines of human fetuses, six to 10 weeks... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 14, 2020 Category: General Medicine Source Type: news

UBCO researchers suggest stool transplants can battle serious infections
(University of British Columbia Okanagan campus) Could number two be number one when it comes to combating recurrent Clostridium difficile (CDI) infections? Using genetic material analysis and machine learning, UBC researchers have pinpointed several key factors to ensure successful fecal microbiota transplants (FMT), which have proven successful in treating bacterial infections in the gut including illnesses like C. difficile, Crohn's Disease, Colitis and even obesity, explains lead author Negin Kazemian. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2020 Category: International Medicine & Public Health Source Type: news