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Mesenchymal stem cells offer novel treatment approach for Crohn's disease fistula
(Mary Ann Liebert, Inc./Genetic Engineering News) A growing body of clinical evidence shows that transplantation of a patient's own mesenchymal stem cells (MSCs) to achieve a cure and prevent recurrent of Crohn's disease-related fistula can be a safe and effective addition to surgery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2017 Category: International Medicine & Public Health Source Type: news

The Efficacy of Probiotics in Inflammatory Bowel Disease The Efficacy of Probiotics in Inflammatory Bowel Disease
This study examined the efficacy of probiotics in inducing and maintaining remission in ulcerative colitis and Crohn disease, as well as preventing relapse in post-operative CD.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 12, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The road to Crohn's disease
(Source: ScienceNOW)
Source: ScienceNOW - September 7, 2017 Category: Science Authors: Kaser, A., Blumberg, R. S. Tags: Cell Biology perspective Source Type: news

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine
Intestinal Paneth cells limit bacterial invasion by secreting antimicrobial proteins, including lysozyme. However, invasive pathogens can disrupt the Golgi apparatus, interfering with secretion and compromising intestinal antimicrobial defense. Here we show that during bacterial infection, lysozyme is rerouted via secretory autophagy, an autophagy-based alternative secretion pathway. Secretory autophagy was triggered in Paneth cells by bacteria-induced endoplasmic reticulum (ER) stress, required extrinsic signals from innate lymphoid cells, and limited bacterial dissemination. Secretory autophagy was disrupted in Paneth ce...
Source: ScienceNOW - September 7, 2017 Category: Science Authors: Bel, S., Pendse, M., Wang, Y., Li, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J., Hooper, L. V. Tags: Cell Biology reports Source Type: news

Old Crohn's Theory Relevant Now? Gastro Endo News Report
(MedPage Today) -- Also, proton pump inhibitors and pancreatic cancer link (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - September 6, 2017 Category: Gastroenterology Source Type: news

Eat seasonal produce for better gut health says experts
The Hadza tribes living in the Savannah have more  diverse gut bacteria, found Stanford researchers. They don't get the gut ailments that we do such as Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2017 Category: Consumer Health News Source Type: news

Asthma Tied to Later Inflammatory Bowel Disease
Findings for Crohn's and early - or late - onset ulcerative colitis (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 25, 2017 Category: Respiratory Medicine Tags: Gastroenterology, Internal Medicine, Allergy, Pathology, Pulmonology, Journal, Source Type: news

Eat seasonal produce for better gut health
The Hadza tribes living in the Savannah have more  diverse gut bacteria, found Stanford researchers. They don't get the gut ailments that we do such as Crohn's disease. (Source: the Mail online | Health)
Source: the Mail online | Health - August 25, 2017 Category: Consumer Health News Source Type: news

Lab tests show molecule appears to spur cell death in tumors, inflammation
(Duke University Medical Center) A drug-like molecule developed by Duke Health researchers appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn's disease. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 17, 2017 Category: Cancer & Oncology Source Type: news

Prophylaxis in Crohn's Disease After Intestinal Resection Prophylaxis in Crohn's Disease After Intestinal Resection
Can prophylactic drug therapy decrease the rate of clinical and endoscopic recurrence following intestinal resection for Crohn's disease? Which regimen may be beneficial?Frontline Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 14, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Scientists make critical insights into T-cell development
(Monash University) Mutations in the gene encoding the enzyme protein tyrosine phosphatase N2 (PTPN2) have been associated with the development of autoimmune disease including Type 1 diabetes, Crohn's Disease and rheumatoid arthritis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

NIH grant to biomedical scientist will advance research on inflammatory bowel disease
(University of California - Riverside) Declan McCole, a biomedical scientist at the University of California, Riverside, has received a $1.83 million grant from the National Institutes of Health to identify how the loss of a protective barrier in the intestine contributes to inflammatory bowel disease (IBD). IBD is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 11, 2017 Category: International Medicine & Public Health Source Type: news

Aevi Genomic Medicine Announces Agreement for $28 Million Private Placement
PHILADELPHIA, Aug. 10, 2017 -- (Healthcare Sales & Marketing Network) -- Aevi Genomic Medicine, Inc. (NASDAQ: GNMX) (the "Company") today announced the execution of a definitive agreement to sell shares of common stock and warrants to purchase c... Biopharmaceuticals, Venture Capital Aevi Genomic Medicine, Crohn's disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - August 10, 2017 Category: Pharmaceuticals Source Type: news

Ulcerative Colitis vs. Crohn ’s Disease – Similarities And Differences
Under normal circumstances, our immune system does its job of protecting the body from infection. However, in people who (Source: Healthy Living - The Huffington Post)
Source: Healthy Living - The Huffington Post - August 7, 2017 Category: Consumer Health News Source Type: news

Can Diet Cause UC or Crohn's Disease?
Title: Can Diet Cause UC or Crohn's Disease?Category: Doctor's& Expert's views on SymptomsCreated: 8/4/2017 12:00:00 AMLast Editorial Review: 8/4/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 4, 2017 Category: Nutrition Source Type: news

Crohn’s disease and ulcerative colitis symptoms: What is inflammatory bowel disease?
CROHN'S disease and Ulcerative Colitis are the two main forms of Inflammatory Bowel Disease, affecting more than 300,000 people in the UK. (Source: Daily Express - Health)
Source: Daily Express - Health - August 2, 2017 Category: Consumer Health News Source Type: news

Country Kids Less Likely to Develop Bowel Disease Than Their City Cousins
Rural living may have protective effect, Canadian study suggests Source: HealthDay Related MedlinePlus Pages: Crohn's Disease, Rural Health Concerns, Ulcerative Colitis (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - July 31, 2017 Category: Consumer Health News Source Type: news

UT Southwestern finds link between backup immune defense, mutation seen in Crohn's disease
(UT Southwestern Medical Center) Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 27, 2017 Category: International Medicine & Public Health Source Type: news

Medical News Today: Rural living tied to lower risk of inflammatory bowel disease
A study of Canadian populations finds that living in urban households is tied to a lower chance of being diagnosed with IBD, particularly in childhood. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 26, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Crohn's disease and colitis: Where you LIVE could affect inflammatory bowel disease
CROHN ’S and colitis are the two main types of inflammatory bowel disease - IBD - and can cause painful symptoms for sufferers. While it isn’t known exactly what causes the condition, experts have now revealed it could be as a result of where you live. (Source: Daily Express - Health)
Source: Daily Express - Health - July 26, 2017 Category: Consumer Health News Source Type: news

Inflammatory bowel disease - where you LIVE could reduce Crohn’s and colitis risk
CROHN ’S and colitis are the two main types of inflammatory bowel disease - IBD - and can cause painful symptoms for sufferers. While it isn’t known exactly what causes the condition, experts have now revealed it could be as a result of where you live. (Source: Daily Express - Health)
Source: Daily Express - Health - July 26, 2017 Category: Consumer Health News Source Type: news

Merck launches biosimilar version of J & J blockbuster Remicade
Merck and Co. Inc. on Monday became the second pharmaceutical company to launch a biosimilar version of Remicade, a drug that generates billions of dollars a year in sales for Johnson& Johnson. Renflexis, the Merck biosimilar product, was approved by the Food and Drug Administration on April 21 as a treatment for rheumatoid arthritis, Crohn's disease, ulcerative colitis and ankylosing spondylitis. It is the first medicine available in the United States under a global biosimilars develop ment and… (Source: bizjournals.com Health Care News Headlines)
Source: bizjournals.com Health Care News Headlines - July 24, 2017 Category: Health Management Authors: John George Source Type: news

Medical News Today: Cake icing pigment could worsen inflammatory bowel disease
Titanium dioxide - a pigment used in foods, cosmetics, and medicines - could compound IBD symptoms. It should be avoided by patients, researchers suggest. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 24, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Crohn's Disease vs. Ulcerative Colitis (UC): Differences and Similarities
Title: Crohn's Disease vs. Ulcerative Colitis (UC): Differences and SimilaritiesCategory: Diseases and ConditionsCreated: 7/24/2017 12:00:00 AMLast Editorial Review: 7/24/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - July 24, 2017 Category: Nutrition Source Type: news

What Conditions is Erythema Nodosum Associated With?
Patient Presentation A 12-year-old male came to clinic with a history of 3-4 days of painful bruising on his shin and lower arms. He had Streptocococcal pharyngitis diagnosed by rapid strep testing approximately 4 weeks previously and had taken all of his amoxicillin antibiotic per his parents. He had recovered without any problems until 3-4 days ago when his legs and arms started to have painful bruises along the shins and lower arms. They were raised, red/purple and painful mainly in the center of the lesions. He denied pain elsewhere nor any fever (Tmax was 99.5F), chills, sweats, weight loss, joint stiffness, abdomina...
Source: PediatricEducation.org - July 24, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Crohn's and colitis: Inflammatory bowel disease could be linked to THIS medication
CROHN ’S disease and colitis - two forms of inflammatory bowel disease - can cause painful, debilitating symptoms and even cause people to have major surgery. (Source: Daily Express - Health)
Source: Daily Express - Health - July 12, 2017 Category: Consumer Health News Source Type: news

Probiotics May Have Benefits for UC, but Not Crohn's Probiotics May Have Benefits for UC, but Not Crohn's
A probiotic called VSL#3 may be effective in inducing remission in active ulcerative colitis (UC), according to findings from a new systematic review and meta-analysis.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - July 11, 2017 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Medical News Today: Scientists find genes that may cause inflammatory bowel disease
From hundreds of genes potentially responsible for inflammatory bowel disease, a new genome-wide analysis focuses on a few that may cause the illness. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 3, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news

Scientists Spot Genes Behind Crohn's, Ulcerative Colitis
Title: Scientists Spot Genes Behind Crohn's, Ulcerative ColitisCategory: Health NewsCreated: 6/29/2017 12:00:00 AMLast Editorial Review: 6/30/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 30, 2017 Category: Nutrition Source Type: news

Scientists Spot Genes Behind Crohn's, Ulcerative Colitis
Large study finds key mutations that may be tied to raised risk for inflammatory bowel disease Source: HealthDay Related MedlinePlus Pages: Crohn's Disease, Digestive Diseases, Genes and Gene Therapy (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 29, 2017 Category: Consumer Health News Source Type: news

Scientists Spot Genes Behind Crohn's, Ulcerative Colitis
THURSDAY, June 29, 2017 -- Researchers say they've come closer to pinpointing genes linked with inflammatory bowel diseases such as Crohn's and ulcerative colitis. For the study, the investigators examined the genomes of nearly 68,000 people. Of... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 29, 2017 Category: General Medicine Source Type: news

Inflammatory bowel disease CURE on horizon: Scientists believe they have found the cause
CROHN ’S disease and colitis - are the two main types of inflammatory bowel disease can cause painful symptoms for sufferers. The exact causes of this disease have previously been unclear, and there is currently no cure. However this could be about to change. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2017 Category: Consumer Health News Source Type: news

Mount Sinai, Pfizer renew research collaboration, building on strong foundation
(The Mount Sinai Hospital / Mount Sinai School of Medicine) The Icahn School of Medicine at Mount Sinai and Pfizer Inc.'s Centers for Therapeutic Innovation (CTI) today announced the renewal of an agreement designed to identify and advance new drug candidates linked to major diseases, such as cancer, rheumatoid arthritis, Crohn's disease, colitis, heart failure, Alzheimer's disease, and cystic fibrosis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 27, 2017 Category: Cancer & Oncology Source Type: news

Crohn's Disease Quiz
Title: Crohn's Disease QuizCategory: MedicineNet QuizCreated: 7/19/2013 12:00:00 AMLast Editorial Review: 6/26/2017 5:42:25 PM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 26, 2017 Category: Nutrition Source Type: news

Arkansas to Accept Medical Marijuana Card Applications
LITTLE ROCK — Arkansas' medical marijuana industry will ramp up in the next week, with the state poised to accept applications from potential patients, growers and distributors. Beginning Friday, the state Medical Marijuana Commission will accept applications from those hoping to grow or supply marijuana, while the Health Department will take applications from those hoping to benefit from the first marijuana-as-medicine program in the Bible Belt. The application periods will run until Sept. 18. State officials expect anywhere from 20,000 to 40,000 people to seek permission to use the drug for a number of health probl...
Source: Arkansas Business - Health Care - June 26, 2017 Category: American Health Source Type: news

High-fat diet found to reduce symptoms of Crohn's disease
(Natural News) A diet high in plant-derived beneficial fats such as coconut oil and cocoa butter may help alleviate symptoms of Crohn’s disease, a new study revealed. Crohn’s disease is a type of inflammatory bowel disease characterized by intestinal swelling, cramping, and diarrhea. The condition affects more than half a million people in the U.S. However, the... (Source: NaturalNews.com)
Source: NaturalNews.com - June 25, 2017 Category: Consumer Health News Source Type: news

Medical News Today: Plant fats alter gut bacteria to ease Crohn's symptoms
A diet high in coconut oil and other plant-derived fats may alter gut bacteria diversity, reducing gut inflammation for patients with Crohn's disease. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 23, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

Crohn’s disease symptoms: THIS diet could prevent signs of bowel condition
CROHN ’S disease is a long-term and debilitating condition, but a high fat diet could help control symptoms of bowel condition. (Source: Daily Express - Health)
Source: Daily Express - Health - June 23, 2017 Category: Consumer Health News Source Type: news

High fat diet reduces gut bacteria, Crohn's disease symptoms
(Case Western Reserve University) Researchers at Case Western Reserve University School of Medicine have shown a high fat diet may lead to specific changes in gut bacteria that could fight harmful inflammation -- a major discovery for patients suffering from Crohn's disease. Crohn's disease, a type of inflammatory bowel syndrome, causes debilitating intestinal swelling, cramping, and diarrhea. The disease affects half a million people in the United States, but its cause is yet unclear. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 22, 2017 Category: International Medicine & Public Health Source Type: news

NICE approves new type of treatment for Crohn ’s disease
Following NICE recommendations, patients with Crohn ’s disease will have routine NHS access to drug ustekinumab, which offers a new way of treating the condition. (Source: NHS Networks)
Source: NHS Networks - June 22, 2017 Category: UK Health Source Type: news

IBS and Crohn’s disease symptoms: THIS could be an embarrassing sign
FLATULENCE is often considered harmless - and even funny - but it could indicate a number of concerning conditions, including IBS and Crohn ’s disease. (Source: Daily Express - Health)
Source: Daily Express - Health - June 21, 2017 Category: Consumer Health News Source Type: news

Single fungus amplifies Crohn's disease symptoms
(Case Western Reserve University) A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 21, 2017 Category: International Medicine & Public Health Source Type: news

Swissmedic accepts review of Takeda and TiGenix ’s file on Cx601
The Swiss Agency for Therapeutic Products (Swissmedic) has accepted a review of Takeda and TiGenix ’s file on investigational compound Cx601 for the treatment of complex perianal fistulas in patients with Crohn's disease. (Source: Pharmaceutical Technology)
Source: Pharmaceutical Technology - June 20, 2017 Category: Pharmaceuticals Source Type: news

Can Crohn's Cause Constipation?
Title: Can Crohn's Cause Constipation?Category: Doctor's& Expert's views on SymptomsCreated: 6/15/2017 12:00:00 AMLast Editorial Review: 6/15/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 15, 2017 Category: Nutrition Source Type: news

Biologics for Mucosal Healing in Crohn's Disease and UC Biologics for Mucosal Healing in Crohn's Disease and UC
Using mucosal healing as a therapeutic endpoint, this review aimed to determine the comparative efficacy of different classes of biologic therapy for treating Crohn's disease and ulcerative colitis.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 15, 2017 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

TiGenix initiates Phase III trial of Cx601 to treat perianal fistulas
Belgium-based biopharmaceutical firm TiGenix has marked the initiation of a Phase III clinical trial of Cx601 for the treatment of complex perianal fistulas in Crohn's disease patients with its first European investigator meeting. (Source: Drug Development Technology)
Source: Drug Development Technology - June 13, 2017 Category: Pharmaceuticals Source Type: news

Diet Therapy Appears to Induce Remission in Some With Biologics-resistant Crohn ’ s Diet Therapy Appears to Induce Remission in Some With Biologics-resistant Crohn ’ s
Some Crohn ’ s disease (CD) patients who are not helped by biologics go into remission when treated with diet alone, new research shows.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - June 9, 2017 Category: Intensive Care Tags: Family Medicine/Primary Care News Source Type: news

Why Do Cigarettes Worsen Crohn's and Help UC?
Title: Why Do Cigarettes Worsen Crohn's and Help UC?Category: Doctor's& Expert's views on SymptomsCreated: 6/9/2017 12:00:00 AMLast Editorial Review: 6/9/2017 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 9, 2017 Category: Nutrition Source Type: news

Medical News Today: Crohn's disease vs. ulcerative colitis: What is the difference?
What is Crohn's disease and what is ulcerative colitis? How are they similar and what are the differences in symptoms, diagnosis, and treatment. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 6, 2017 Category: Consumer Health News Tags: Crohn's / IBD Source Type: news