A T-cell stimulatory protein and interleukin-10 synergize to prevent gut inflammation
(University of Alabama at Birmingham) Researchers have found an unexpected synergy between a T-cell stimulatory protein -- the ICOS ligand -- and interleukin-10, an immunoregulatory cytokine, to prevent inflammatory bowel disease in mice. The study will aid the understanding of, and future research into, this immune disorder, which includes Crohn's disease and ulcerative colitis. About 1.6 million Americans have inflammatory bowel disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 25, 2021 Category: International Medicine & Public Health Source Type: news

Antibody injections could become more affordable with new production method
(Penn State) Antibody injections are a highly desirable treatment for people with chronic diseases such as cancer, psoriasis, Crohn's disease and arthritis. And recently, antibodies have been in the news as a promising treatment for severe cases of COVID-19. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 22, 2021 Category: International Medicine & Public Health Source Type: news

Common inflammatory bowel disease treatment linked to reduced COVID-19 antibody response
(University of Exeter) The findings arose from the CLARITY study, which recruited 6,935 patients with Crohn's disease and ulcerative colitis from 92 UK hospitals between September and December 2020. It found that fewer than half of people with IBD who were treated with infliximab had detectable antibodies after SARS-CoV-2 infection, the coronavirus that causes COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 22, 2021 Category: Infectious Diseases Source Type: news

Could a Yeast Found in Cheese Be Key to Easing Crohn's Disease?
WEDNESDAY, March 17, 2021 -- A new tissue infection has been identified in Crohn ' s disease patients, and researchers say their finding could ultimately lead to better treatment of the common inflammatory bowel disease. Areas of unhealed wounds in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 17, 2021 Category: General Medicine Source Type: news

Could a Yeast Found in Cheese Be Key to Easing Crohn's Disease?
Title: Could a Yeast Found in Cheese Be Key to Easing Crohn ' s Disease?Category: Health NewsCreated: 3/17/2021 12:00:00 AMLast Editorial Review: 3/17/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - March 17, 2021 Category: Nutrition Source Type: news

Mayo Clinic Q & amp;A podcast: The increasing prevalence of inflammatory bowel disease
Inflammatory bowel disease is common, and it is becoming more common in many populations. Dr. William Faubion Jr., a Mayo Clinic gastroenterologist, says inflammatory bowel disease is an umbrella term that covers Crohn's disease and ulcerative colitis, and that inflammatory bowel disease is an emerging public health problem. "The most recent estimates would be that, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 16, 2021 Category: Databases & Libraries Source Type: news

Swallowable Capsule-Camera Instead of Endoscopy: Now in Patients Swallowable Capsule-Camera Instead of Endoscopy: Now in Patients
Now being tested in patients in England, a swallowable capsule device transmits images of the inside of the gut that can reveal cancer and conditions such as Crohn ' s disease.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Swallowable Capsule-Camera Instead of Endoscopy for Use at Home Swallowable Capsule-Camera Instead of Endoscopy for Use at Home
Now being tested in patients in England, a swallowable capsule device transmits images of the inside of the gut that can reveal cancer and conditions such as Crohn ' s disease.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 12, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news

Debaryomyces is enriched in Crohns disease intestinal tissue and impairs healing in mice
Alterations of the mycobiota composition associated with Crohn’s disease (CD) are challenging to link to defining elements of pathophysiology, such as poor injury repair. Using culture-dependent and -independent methods, we discovered that Debaryomyces hansenii preferentially localized to and was abundant within incompletely healed intestinal wounds of mice and inflamed mucosal tissues of CD human subjects. D. hansenii cultures from injured mice and inflamed CD tissues impaired colonic healing when introduced into injured conventionally raised or gnotobiotic mice. We reisolated D. hansenii from injured areas of these...
Source: ScienceNOW - March 11, 2021 Category: Science Authors: Jain, U., Ver Heul, A. M., Xiong, S., Gregory, M. H., Demers, E. G., Kern, J. T., Lai, C.-W., Muegge, B. D., Barisas, D. A. G., Leal-Ekman, J. S., Deepak, P., Ciorba, M. A., Liu, T.-C., Hogan, D. A., Debbas, P., Braun, J., McGovern, D. P. B., Underhill, D Tags: Medicine, Diseases, Microbiology reports Source Type: news

Hyperbaric Oxygen for Perianal Fistulas in Crohn's Disease Hyperbaric Oxygen for Perianal Fistulas in Crohn's Disease
This study assessed the efficacy, safety and feasibility of hyperbaric oxygen therapy in Crohn ' s disease patients with therapy-refractory perianal fistulas.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 8, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Immune-mediated Diseases and Risk of IBD Immune-mediated Diseases and Risk of IBD
Are individuals with other immune-mediated diseases at greater risk of developing ulcerative colitis or Crohn ' s disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Adherent-Invasive E. Coli Metabolism Drives Inflammation in Crohn's Disease Adherent-Invasive E. Coli Metabolism Drives Inflammation in Crohn's Disease
Researchers have identified the process by which adherent-invasive Escherichia coli (AIEC) bacteria drive inflammation in Crohn ' s disease.Medscape (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 18, 2021 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

New potential therapy for Crohn's disease in children
(Ann& Robert H. Lurie Children's Hospital of Chicago) Scientists from the Stanley Manne Children's Research Institute at Ann& Robert H. Lurie Children's Hospital of Chicago demonstrated that a nanotherapy reduces intestinal inflammation and shrinks lesions in a rodent model of severe Crohn's disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 17, 2021 Category: International Medicine & Public Health Source Type: news

Avexegen Therapeutics Receives a $2.94M NIH Grant to Advance Treatment for Inflammatory Bowel Disease
SAN FRANCISCO, Feb. 15, 2021 -- (Healthcare Sales & Marketing Network) -- Avexegen Therapeutics Inc. today announced that it has received a Phase 2 award of $2.94 million under the National Institutes of Health's Small Business Innovation Research Program... Biopharmaceuticals, Gastroenterology Avexegen Therapeutics, inflammatory bowel disease, Crohn's Disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 15, 2021 Category: Pharmaceuticals Source Type: news

Study identifies 'Achilles heel' of bacteria linked to Crohn's disease
(Weill Cornell Medicine) The discovery of an " Achilles heel " in a type of gut bacteria that causes intestinal inflammation in patients with Crohn's disease may lead to more targeted therapies for the difficult to treat disease, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 5, 2021 Category: International Medicine & Public Health Source Type: news