What Is the Life Expectancy of Someone with Crohn's Disease?
Title: What Is the Life Expectancy of Someone with Crohn ' s Disease?Category: Diseases and ConditionsCreated: 8/4/2020 12:00:00 AMLast Editorial Review: 8/4/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 4, 2020 Category: Nutrition Source Type: news

An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease
Anti–tumor necrosis factor (anti-TNF) therapy resistance is a major clinical challenge in inflammatory bowel disease (IBD), due, in part, to insufficient understanding of disease-site, protein-level mechanisms. Although proteomics data from IBD mouse models exist, data and phenotype discrepancies contribute to confounding translation from preclinical animal models of disease to clinical cohorts. We developed an approach called translatable components regression (TransComp-R) to overcome interspecies and trans-omic discrepancies between mouse models and human subjects. TransComp-R combines mouse proteomic data with pa...
Source: Signal Transduction Knowledge Environment - August 3, 2020 Category: Science Authors: Brubaker, D. K., Kumar, M. P., Chiswick, E. L., Gregg, C., Starchenko, A., Vega, P. N., Southard-Smith, A. N., Simmons, A. J., Scoville, E. A., Coburn, L. A., Wilson, K. T., Lau, K. S., Lauffenburger, D. A. Tags: STKE Research Articles Source Type: news

Ortikos (budesonide), the First and Only Once-Daily Dose for Treatment of Mild to Moderate Crohn ’s Disease, Now Available in the U.S.
Parsippany, NJ– July 29, 2020– Ferring Pharmaceuticals Inc. today announced the launch of Ortikos (budesonide) in the United States, which is approved as the only once-daily treatment of mild to moderate active Crohn’s disease... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 29, 2020 Category: Drugs & Pharmacology Source Type: news

Help Shape Our Reporting on Disability and Accessibility in America
Our journalists want to hear your questions about and experiences with disability and accessibility in the U.S. (Source: NYT Health)
Source: NYT Health - July 10, 2020 Category: Consumer Health News Authors: Hannah Wise Tags: Crohn ' s Disease Americans With Disabilities Act United States Source Type: news

Inflammatory Bowel Disease Tied to Increased Dementia Risk
Those with Crohn ’s disease or ulcerative colitis had higher rates of Alzheimer’s disease and other forms of dementia. (Source: NYT Health)
Source: NYT Health - July 2, 2020 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Alzheimer ' s Disease Dementia Digestive Tract Crohn Source Type: news

Could Crohn's, Colitis Raise Dementia Risk?
Title: Could Crohn ' s, Colitis Raise Dementia Risk?Category: Health NewsCreated: 6/23/2020 12:00:00 AMLast Editorial Review: 6/24/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 24, 2020 Category: Nutrition Source Type: news

Ultrasound Score Promising Measure of Crohn's Disease Ultrasound Score Promising Measure of Crohn's Disease
An ultrasound activity index combining bowel-wall thickness and color Doppler appears to be a useful surrogate marker of endoscopic activity in patients with Crohn ' s disease, according to Norwegian researchers.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - June 23, 2020 Category: Pathology Tags: Gastroenterology News Source Type: news

Could Crohn's, Colitis Raise Dementia Risk?
TUESDAY, June 23, 2020 -- People with inflammatory bowel disease might be vulnerable to developing dementia, a new study suggests. Inflammatory bowel disease, or IBD, is an umbrella term for ulcerative colitis and Crohn ' s disease. Both cause chronic... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 23, 2020 Category: General Medicine Source Type: news

Cloning stem cells to find a cure for Crohn's disease
(University of Houston) Researchers at the University of Houston Stem Cell Center are developing new drug therapies to selectively destroy rogue cells they found in biopsies of pediatric Crohn's patients, to create new treatments for the disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 18, 2020 Category: International Medicine & Public Health Source Type: news

Treatment With Two Biologics in Refractory Crohn's Disease Treatment With Two Biologics in Refractory Crohn's Disease
Might simultaneous treatment with two biologics provide improved outcomes in patients who previously have failed multiple biologic therapies?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 17, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Perianal Fistulizing Complications Preventable in Crohn Disease
TUESDAY, June 16, 2020 -- For young patients with Crohn disease (CD), use of steroid-sparing therapy (SST) is associated with a reduced risk for perianal fistulizing complications (PFCs), according to a study published online June 9 in JAMA Network... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 16, 2020 Category: Pharmaceuticals Source Type: news

Steroid-sparing therapies reduce fistula risk by 60% in young people with Crohn's, study finds
Steroid-sparing treatments can prevent young people with Crohn's disease from developing perianal fistulas, a serious complication associated with the condition, according to a study published by JAMA Network Open. (Source: Health News - UPI.com)
Source: Health News - UPI.com - June 9, 2020 Category: Consumer Health News Source Type: news

What Are the First Signs of Crohn ’s Disease?
Title: What Are the First Signs of Crohn ’s Disease?Category: Diseases and ConditionsCreated: 6/4/2020 12:00:00 AMLast Editorial Review: 6/4/2020 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - June 4, 2020 Category: Nutrition Source Type: news

Understanding a gene's role in inflammatory bowel disease
(University of California - Riverside) A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside. The work is made possible by a National Institutes of Health grant exceeding $2.5 million. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2020 Category: International Medicine & Public Health Source Type: news

Exclusive Enteral Nutrition Formulas Used in Crohn's Disease Exclusive Enteral Nutrition Formulas Used in Crohn's Disease
This study analyzed nonnutrient food ingredients and food additive composition of EEN formulas.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news