Tofacitinib Maintenance Dose for Patients With UC Tofacitinib Maintenance Dose for Patients With UC
This study analyzed the efficacy and safety of two adjustments of tofacitinib maintenance dosing for patients with ulcerative colitis.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - February 3, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Biologics May Have Changed the Natural History of Ulcerative Colitis Biologics May Have Changed the Natural History of Ulcerative Colitis
The rate of colectomy within the first year after hospital admission for ulcerative colitis has declined in the modern era of biologics, suggesting the advent of biologic therapy has changed the natural history of the disease, researchers report.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - January 30, 2020 Category: Surgery Tags: Gastroenterology News Source Type: news

Vedolizumab and Malignancy Incidence Vedolizumab and Malignancy Incidence
This study analyzed the long-term incidence of malignancy with vedolizumab, a gut-selective antibody approved to treat moderate-to-severe Crohn's disease and ulcerative colitis in adults.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 22, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

New AGA guideline outlines treatment best practices for ulcerative colitis patients
(American Gastroenterological Association) An increasing number of drugs are available for long-term management of moderate to severe UC, leading to questions about treatment strategies for optimal patient care. A new clinical guideline from the American Gastroenterological Association, published in Gastroenterology, the official journal of the AGA Institute, provides recommendations for the management of adult outpatients with moderate to severe UC as well as adult hospitalized patients with acute severe ulcerative colitis (ASUC). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 21, 2020 Category: International Medicine & Public Health Source Type: news

Colorectal Cancer Risk Still Up in Patients With Ulcerative Colitis
Even after adjustment for tumor stage, patients with ulcerative colitis have higher risk for CRC mortality (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - January 17, 2020 Category: Cancer & Oncology Tags: Family Medicine, Gastroenterology, Internal Medicine, Oncology, Journal, Source Type: news

Colorectal Cancer Risk Still Up in Patients With Ulcerative Colitis
FRIDAY, Jan. 17, 2020 -- Patients with ulcerative colitis have an increased risk for colorectal cancer and colorectal cancer mortality, according to a study published in the Jan. 11 issue of The Lancet. Ola Ol én, M.D., from the Karolinska... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 17, 2020 Category: Pharmaceuticals Source Type: news

Fungal Alterations in Inflammatory Bowel Diseases Fungal Alterations in Inflammatory Bowel Diseases
This review explores the role of gut fungi in patients with Crohn's disease and ulcerative colitis. Might modulation of the fungal microbiota present a therapeutic opportunity for IBD?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 15, 2020 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Colorectal cancer risk remains despite modern treatment for ulcerative colitis
(Karolinska Institutet) Patients with the inflammatory bowel disease ulcerative colitis have a higher risk of dying from colorectal cancer, despite modern therapy, even though the risk has declined in recent years. This is according to a new study published in the scientific journal The Lancet by a team of Swedish and Danish researchers. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 9, 2020 Category: Cancer & Oncology Source Type: news

Ultrasound Effective in Monitoring Ulcerative Colitis Ultrasound Effective in Monitoring Ulcerative Colitis
Intestinal ultrasound (IUS) is an effective non-invasive tool for monitoring disease - and possibly treatment response - in patients with ulcerative colitis (UC), according to German researchers.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 6, 2020 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

1999 to 2017 Saw Drop in IBD Hospitalization Rate for Whites
THURSDAY, Dec. 12, 2019 -- From 1999 to 2017, the hospitalization rate for Crohn disease and ulcerative colitis decreased among non-Hispanic white Medicare beneficiaries aged ≥65 years, but not among non-Hispanic blacks, according to research... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 12, 2019 Category: Pharmaceuticals Source Type: news

FDA Approves Xeljanz XR (tofacitinib) Extended-Release Tablets for the Treatment of Ulcerative Colitis
December 12, 2019 - Pfizer Inc. (NYSE:PFE) announced today that the U.S. Food and Drug Administration (FDA) has approved Xeljanz XR (tofacitinib) extended-release 11 mg and 22 mg tablets for the once-daily treatment of adult patients with moderately... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - December 12, 2019 Category: Drugs & Pharmacology Source Type: news

A vaccine against chronic inflammatory diseases
Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their intestinal flora along with excessive levels of bacteria that express a protein called flagellin, which favors their mobility. (Source: World Pharma News)
Source: World Pharma News - December 11, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Endoscopic Techniques for Dysplasia Surveillance in IBD Endoscopic Techniques for Dysplasia Surveillance in IBD
Which endoscopic procedure best identifies neoplasia in patients with ulcerative colitis or Crohn disease?Alimentary Pharmacology & Therapeutics (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - December 4, 2019 Category: Allergy & Immunology Tags: Gastroenterology Journal Article Source Type: news

Drug decreases gut leakiness associated with ulcerative colitis
(University of California - Riverside) A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 4, 2019 Category: International Medicine & Public Health Source Type: news

Drinking kudingcha can help lower your risk of colitis
(Natural News) Researchers from the Chongqing University of Education in China looked at the potential of functional foods – in particular, kudingcha or kuding tea – to treat ulcerative colitis. They found that kuding tea could help treat and prevent ulcerative colitis without side effects. Kuding tea is a bitter-tasting tea which is popular in China. It is used to quench thirst,... (Source: NaturalNews.com)
Source: NaturalNews.com - December 2, 2019 Category: Consumer Health News Source Type: news

FDA approves Pfizer's biosimilar, ABRILADA ™ (adalimumab-afzb) for multiple inflammatory conditions
Pfizer Inc. (NYSE: PFE) announced the United States (U.S.) Food and Drug Administration (FDA) has approved ABRILADA™ (adalimumab-afzb), as a biosimilar to Humira® (adalimumab),(1) for the treatment of certain patients with rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult Crohn's disease, ulcerative colitis and plaque psoriasis.(2) (Source: World Pharma News)
Source: World Pharma News - December 2, 2019 Category: Pharmaceuticals Tags: Featured Pfizer Business and Industry Source Type: news

What can TCM do against ulcerative colitis?
(Natural News) Ulcerative colitis is a type of inflammatory bowel disease that causes sores along the intestinal tract. This disease can be debilitating, and if left untreated, it can also lead to life-threatening complications such as severe bleeding and colon cancer. Today, ulcerative colitis remains without a cure, and relief from its symptoms is solely dependent... (Source: NaturalNews.com)
Source: NaturalNews.com - October 23, 2019 Category: Consumer Health News Source Type: news

FDA OKs Ustekinumab (Stelara) for Moderate to Severe UC FDA OKs Ustekinumab (Stelara) for Moderate to Severe UC
Ustekinumab was more effective than placebo for inducing and maintaining remission and promoting mucosal healing in a study of adults with moderately to severely active ulcerative colitis.FDA Approvals (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - October 22, 2019 Category: Internal Medicine Tags: Gastroenterology News Alert Source Type: news

Janssen Announces FDA Approval of Stelara (ustekinumab) for the Treatment of Adults with Moderately to Severely Active Ulcerative Colitis
HORSHAM, PENNSYLVANIA, October 21, 2019– The Janssen Pharmaceutical Companies of Johnson& Johnson announced today the U.S. Food and Drug Administration’s (FDA) approval of Stelara (ustekinumab) for the treatment of adult patients... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - October 21, 2019 Category: Drugs & Pharmacology Source Type: news

Janssen Announces U.S. FDA Approval of STELARA ® (ustekinumab) for the Treatment of Adults with Moderately to Severely Active Ulcerative
In the Phase 3 pivotal trial, more than 40 percent of patients receiving STELARA subcutaneous (SC) injections every 8 weeks were in clinical remission at one year and not taking corticosteroidsSTELARA is the first and only approved treatment for ulcerative colitis to demonstrate improvement of the colon as measured by a novel histologic-endoscopic mucosal improvement endpoint (Source: Johnson and Johnson)
Source: Johnson and Johnson - October 21, 2019 Category: Pharmaceuticals Source Type: news

Ulcerative Colitis: Clinical Trial Endpoints Guidance for Industry
Clinical / Medical (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 17, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Vedolizumab good value in ulcerative colitis in Japan
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - October 1, 2019 Category: Drugs & Pharmacology Source Type: news

DDT COA #000040: Ulcerative Colitis Patient-Reported Outcomes Signs and Symptoms (UC-PRO/SS)
Clinical Outcome Assessments (COA) Qualification Submissions Office of Drug Evaluation (ODE) III Division of Gastroenterology and Inborn Error Products (DGIEP) DDT COA Number DDT COA #000040 (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 27, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Beyond TNF Inhibitors in Ulcerative Colitis: Promising Data Beyond TNF Inhibitors in Ulcerative Colitis: Promising Data
Two recent studies highlight the options of alternative biologic agents and regimens for patients with ulcerative colitis who are unable to receive anti-tumor necrosis factor (TNF) therapies.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 27, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Vedolizumab Beats Adalimumab for Ulcerative Colitis Remissions
WEDNESDAY, Sept. 25, 2019 -- In moderate-to-severe ulcerative colitis, vedolizumab is superior to adalimumab for achieving clinical remission and endoscopic improvement, but not corticosteroid-free clinical remission, and ustekinumab is superior to... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 25, 2019 Category: Pharmaceuticals Source Type: news

Effectiveness of Infliximab vs. Biosimilar CT-P13 in Colitis Effectiveness of Infliximab vs. Biosimilar CT-P13 in Colitis
The infliximab biosimilar CT-P13 has been approved for the treatment of ulcerative colitis. Are they clinically equivalent in safety and efficacy?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 25, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

The Association between Inflammatory Bowel Disease and Periodontal Conditions: Is There a Common Bacterial Etiology?
CONCLUSION:A number of studies have showed an association between PD and IBD. Both diseases share genetic and environmental etiological factors. The precise role of intestinal bacteria remains vague. The periodontal microbiota that might be involved in the association of these diseases are Fusobacterium nucleatum, Campylobacter rectus and Campylobacter concisus. Fungal and viral microbiota dysbiosis should also be evaluated as common pathogenic pathways in IBD and periodontal disease. (Source: Dental Technology Blog)
Source: Dental Technology Blog - September 24, 2019 Category: Dentistry Source Type: news

Ulcerative Colitis
Title: Ulcerative ColitisCategory: Diseases and ConditionsCreated: 11/9/2012 12:00:00 AMLast Editorial Review: 9/11/2019 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - September 11, 2019 Category: Nutrition Source Type: news

Compounds in TCM prove effective against ulcerative colitis
(Natural News) Traditional Chinese medicine (TCM) continues to be validated by scientific investigations as new research proves that TCM is effective in treating ulcerative colitis. Ulcerative colitis is an inflammatory bowel disease that causes long-lasting inflammation and ulcers in the digestive tract. It is caused by a variety of factors, including genetic predisposition, epithelial barrier... (Source: NaturalNews.com)
Source: NaturalNews.com - August 28, 2019 Category: Consumer Health News Source Type: news

Three-year Effectiveness and Safety of Vedolizumab for IBD Three-year Effectiveness and Safety of Vedolizumab for IBD
This study examined the effectiveness and safety of long-term vedolizumab maintenance therapy in patients with moderate-to-severe active ulcerative colitis and Crohn's disease.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 12, 2019 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Ulcerative Colitis Outcomes Similar for Smokers, Nonsmokers
FRIDAY, Aug. 9, 2019 -- Smokers and nonsmokers with ulcerative colitis (UC) have similar outcomes, according to a study published online Aug. 6 in Alimentary Pharmacology and Therapeutics. Jonathan Blackwell, B.M.B.S., from St. George's University... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 9, 2019 Category: Pharmaceuticals Source Type: news

FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR)
Listen to an audio podcast of the July 26, 2019 FDA Drug Safety Communication on FDA approval of Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - August 5, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA: Blood Clot, Death Risk Up With Higher Dose of Tofacitinib
FRIDAY, July 26, 2019 -- New warnings about an increased risk of thrombosis and of death among ulcerative colitis patients taking the 10 mg twice daily dose of the drug tofacitinib (Xeljanz, Xeljanz XR) have been issued by the U.S. Food and Drug... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 26, 2019 Category: Pharmaceuticals Source Type: news

FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR)
FDA adds Boxed Warning about increased risk of blood clots and death with 10 mg twice daily dose of tofacitinib (Xeljanz). This dose is not approved for arthritis. For ulcerative colitis, only use in patients who have failed or do not tolerate TNF blockers. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - July 26, 2019 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Etanercept Tx for Autoimmune Disease May Up Risk for IBD
MONDAY, July 15, 2019 -- Patients with autoimmune diseases have an increased risk for being diagnosed with Crohn disease (CD) or ulcerative colitis (UC) while under treatment with etanercept, according to a study published online July 2 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 15, 2019 Category: Pharmaceuticals Source Type: news

New method divides patients with ulcerative colitis in groups
(Karolinska Institutet) Researchers at Karolinska Institutet in Sweden have found a way of using gene expression conserved across species to divide patients with the inflammatory bowel disease ulcerative colitis into two distinct groups. The findings are published in the journal Nature Communications, and the researchers hope that the method can also be used to subdivide other autoimmune diseases. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 28, 2019 Category: International Medicine & Public Health Source Type: news

Medical News Today: What to know about Xeljanz
This article provides an overview of its uses, how it works, and side effect warnings. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 25, 2019 Category: Consumer Health News Tags: Rheumatoid Arthritis Source Type: news

Biologics in IBD: More Thoughtful Use Could Improve Outcomes Biologics in IBD: More Thoughtful Use Could Improve Outcomes
The marketplace introduction of infliximab for the treatment of IBD did not reduce hospitalization or surgery rates in a large population of patients with Crohn disease and ulcerative colitis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 20, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Peptides that mimic ‘good cholesterol’ reverse inflammatory bowel disease in mice
FINDINGSPeptides that mimic  the function of HDL cholesterol, which has been dubbed “good cholesterol,” can treat the underlying inflammation associated with inflammatory bowel disease, or IBD, according to new research in mice. The same work revealed new details on how IBD can develop and what other types of drugs may wo rk to treat the disease.BACKGROUNDThe most common types of IBD, a chronic inflammatory disease of the digestive tract, are Crohn ’s disease and ulcerative colitis. There are few effective treatments for IBD, and a majority of patients will eventually need surgery, according to previ...
Source: UCLA Newsroom: Health Sciences - June 11, 2019 Category: Universities & Medical Training Source Type: news

Inflammatory bowel disease patients have higher health costs
(Reuters Health) - People with inflammatory bowel disease - either Crohn's disease or ulcerative colitis - may incur health costs more than three times higher than individuals without these conditions, a U.S. study suggests. (Source: Reuters: Health)
Source: Reuters: Health - June 7, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Central Retinal Vein Occlusion Rarely Complicates Ulcerative Colitis Central Retinal Vein Occlusion Rarely Complicates Ulcerative Colitis
Central retinal vein occlusion (CRVO) can rarely complicate the course of inflammatory bowel disease (IBD), according to a case series.Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - May 22, 2019 Category: Opthalmology Tags: Gastroenterology News Source Type: news

Medical News Today: What to know about ulcerative colitis and cancer
Ulcerative colitis (UC) causes inflammation in the digestive system. This may increase the risk of certain cancers. Learn more about the link between UC and cancer, as well as when to see a doctor and how to reduce the risk of cancer, here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 21, 2019 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Medical News Today: Ulcerative colitis: Does drinking alcohol make it worse?
Ulcerative colitis causes inflammation in the digestive system. Alcohol may cause the condition to become worse. Learn more about the links between ulcerative colitis and alcohol here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 17, 2019 Category: Consumer Health News Tags: Ulcerative Colitis Source Type: news

Medical News Today: What to know about ulcerative colitis and pregnancy
Ulcerative colitis causes inflammation of parts of the digestive system. It is possible for women with ulcerative colitis to get pregnant, have a healthy pregnancy, and give birth safely. Learn more about ulcerative colitis and pregnancy here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 15, 2019 Category: Consumer Health News Tags: Ulcerative Colitis Source Type: news

Higher Risk for Cancer, Mortality Seen With Pediatric - Onset IBD
Risk for cancer, mortality increased for patients with pediatric - onset ulcerative colitis, Crohn disease (Source: The Doctors Lounge - Psychiatry)
Source: The Doctors Lounge - Psychiatry - May 13, 2019 Category: Psychiatry Tags: Gastroenterology, Infections, Oncology, Pathology, Pediatrics, Psychiatry, Journal, Source Type: news

Breath Analysis Shows Promise in Distinguishing IBD Types Breath Analysis Shows Promise in Distinguishing IBD Types
A breath analyzer can identify inflammatory bowel disease (IBD) in affected individuals and distinguish ulcerative colitis (UC) from Crohn's disease (CD), a pilot study reveals.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 10, 2019 Category: Consumer Health News Tags: Gastroenterology News Source Type: news

Study: Childhood inflammatory bowel disease raises cancer risk in adulthood
People had a 2.5 times higher risk of developing cancer if they had ulcerative colitis before they turned 18, new research shows. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 9, 2019 Category: Consumer Health News Source Type: news

Inflammatory bowel disease during childhood linked to higher cancer rates and early death
(Wiley) A new Alimentary Pharmacology& Therapeutics study revealed an increased risk of cancer and early death in individuals who developed inflammatory bowel disease-including ulcerative colitis (UC) and Crohn's disease (CD) -- during childhood. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 9, 2019 Category: International Medicine & Public Health Source Type: news

Mother-of-two ditches vegan diet she followed for 15 YEARS and now she ONLY eats meat
Nicole Carter, 44, of California, said her health plummeted and she was diagnosed with digestive condition ulcerative colitis in 2012. She switched to a carnivore diet and said she has never felt better. (Source: the Mail online | Health)
Source: the Mail online | Health - May 8, 2019 Category: Consumer Health News Source Type: news

In Men, Low BMI Tied to Later Inflammatory Bowel Disease
TUESDAY, May 7, 2019 -- Low body mass index (BMI) among men entering adult life is associated with an increased incidence of Crohn disease (CD) and ulcerative colitis (UC) up to 40 years later, according to a study published online April 23 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 7, 2019 Category: Pharmaceuticals Source Type: news