Astragalin Promotes Osteoblastic Differentiation in MC3T3-E1 Cells and Bone Formation in vivo

This study was carried out in accordance with the recommendations of the NIH guidelines for the care and use of laboratory animals. The protocol was approved by the Committees of Animal Ethics and Experimental Safety of Binzhou Medical University. Author Contributions DL supervised the whole project. LL, DW, and DL performed the major research and wrote the manuscript with equal contributions. YQ, MX, LZ, WX, XL, and LY provided technical support. SY and QZ provided their professional expertise. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments This work was supported by the National Natural Science Foundation of China (Grant nos. 81872162 and 81602556 to DL; 81503465 to LL and 31870338 to QZ), the Natural Science Foundation of Shandong Province of China (ZR2017JL030), Taishan Scholars Construction Engineering of Shandong Province (to DL), Yantai High-End Talent Introduction Plan Double Hundred (to DL), the Scientific Research Foundation of Binzhou Medical University (Grant no. BY2016KYQD01 to DL), the Dominant Disciplines' Talent Team Development Scheme of Higher Education of Shandong Province (to DL), and the Natural Science Foundation of Guangdong Province (2015A030310263). Supplementary Material The Supplementary Material for this article can be found online at: https://www.frontiersin.org...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research