The effect of oral analgesic premedication on the success rate of inferior alveolar nerve block for teeth with irreversible pulpitis: A randomized clinical trial
Conclusions: Premedication with pharmapain (an anti-inflammatory agent) and dexamethasone (a corticosteroid) does not enhance the success rate of the IANB technique in mandibular molars with irreversible pulpitis compared to placebo. However, the use of dexamethasone was significantly more effective than pharmapain in reducing pain severity at inserting endodontic files. (Source: Dental Technology Blog)
Source: Dental Technology Blog - March 19, 2024 Category: Dentistry Source Type: news

Long-Release Implant Available for Diabetic Macular Oedema Long-Release Implant Available for Diabetic Macular Oedema
The implant requires less frequent replacement than the dexamethasone alternative.Medscape News UK (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - March 14, 2024 Category: Endocrinology Tags: Ophthalmology Source Type: news

A Blenrep Comeback? Cancer Vaccine for Dogs; U.K. Snubs Enhertu
(MedPage Today) -- An interim analysis of the DREAMM-8 trial showed belantamab mafodotin (Blenrep) improved progression-free survival when combined with pomalidomide (Pomalyst) and dexamethasone as second-line treatment for patients with relapsed... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - March 7, 2024 Category: Hematology Source Type: news

Three-Drug Combo Wins for Opioid-Sparing Pain Relief After Hip Replacement
(MedPage Today) -- Pain control during the first 24 hours after total hip arthroplasty was maximized in a randomized trial with a combination of acetaminophen (A), ibuprofen (I), and dexamethasone (D), as opposed to various combinations of two... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - March 7, 2024 Category: Primary Care Source Type: news

WITHDRAWN: FDA grants accelerated approval to melphalan flufenamide for relapsed or refractory multiple myeloma
FDA announced its final decision to withdraw approval of melphalan flufenamide (Pepaxto) with dexamethasone to treat certain patients with multiple myeloma. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 23, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news

FDA issues final decision to withdraw approval of Pepaxto (melphalan flufenamide)
FDA has announced its decision to withdraw approval of Pepaxto (melphalan flufenamide), which was approved for use in combination with dexamethasone to treat certain patients with multiple myeloma. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - February 23, 2024 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Triplet Therapy Including Belamaf Prolongs Survival in Multiple Myeloma
FRIDAY, Feb. 9, 2024 -- For patients with relapsed or refractory multiple myeloma (RRMM), triplet therapy of belantamab mafodotin (belamaf) plus bortezomib and dexamethasone (BVd) improves outcomes, with an acceptable safety profile, according to a... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 9, 2024 Category: Pharmaceuticals Source Type: news

Daratumumab Added to Standard Therapy Improves PFS in Multiple Myeloma
(MedPage Today) -- Data presented at the 2023 American Society of Hematology (ASH) annual meeting demonstrated that adding the anti-CD38 antibody daratumumab (Darzalex) to bortezomib (Velcade), lenalidomide (Revlimid), and dexamethasone (VRd) significantly... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - January 4, 2024 Category: Hematology Source Type: news

No Benefit to Salvage Transplant in R/R Multiple Myeloma No Benefit to Salvage Transplant in R/R Multiple Myeloma
Long-term follow-up shows no progression-free or overall survival advantage among patients who received salvage transplant vs continuous lenalidomide plus dexamethasone.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 13, 2023 Category: Cancer & Oncology Tags: Hematology-Oncology Source Type: news

ASH: Daratumumab Beneficial for Patients With Multiple Myeloma
WEDNESDAY, Dec. 13, 2023 -- For transplantation-eligible patients with newly diagnosed multiple myeloma, the addition of subcutaneous daratumumab combined with bortezomib, lenalidomide, and dexamethasone induction and consolidation therapy and with... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 13, 2023 Category: Pharmaceuticals Source Type: news

Another Long-Acting Steroid Shot Impresses in Knee OA
(MedPage Today) -- SAN DIEGO -- Two intra-articular injections of a liposomal formulation of dexamethasone given 6 months apart provided a year of pain relief for patients with osteoarthritis (OA) of the knee, a researcher said here. In a phase... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 16, 2023 Category: Rheumatology Source Type: news

Dexamethasone No Benefit in HIV-Positive With Tuberculous Meningitis
THURSDAY, Oct. 12, 2023 -- For HIV-positive adults with tuberculous meningitis, adjunctive dexamethasone does not confer a benefit with respect to survival, according to a study published in the Oct. 12 issue of the New England Journal of... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 12, 2023 Category: Pharmaceuticals Source Type: news

Steroid Fails to Boost Survival in Advanced HIV Patients With TB Meningitis
(MedPage Today) -- Adding dexamethasone to treatment for tuberculous (TB) meningitis among heavily immunosuppressed HIV-positive patients in a low-resource setting did not significantly improve survival or confer any other measured benefits, a... (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - October 11, 2023 Category: Infectious Diseases Source Type: news

ชา Tapee Tea (ชาสมุนไพรตรา เทพี) มีส่วนผสมของยาที่ไม่ได้แจ้งบนฉลาก
ผลการวิเคราะห์ในห้องปฏิบัติการของ FDA ยืนยันว่าชา Tapee Tea มีตัวยาเดกซาเมทาโซน (dexamethasone) และยาไพร็อกซิแคม (piroxicam) ซึ่งไม ่ได้ระบุไว้บนฉลากผลิตภัณฑ์ (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - September 7, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Exposure to Outdoor Cold Air Beneficial for Children With Croup
TUESDAY, Aug. 1, 2023 -- A 30-minute exposure to outdoor cold air is beneficial for reducing clinical symptoms in children with croup as an adjunct to oral dexamethasone, according to a study published online Aug. 1 in Pediatrics. Johan N. Siebert,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - August 1, 2023 Category: Pharmaceuticals Source Type: news