Can't stand the rain? How wet weather affects human behaviour
Rainfall affects our mood, our propensity to commit crime and how hungry we feel – but why?It ’s raining, it’s pouring, the old man is snoring. He bumped his head when he went to bed, and he couldn’t get up in the morning. This was possibly because in the absence of sunlight his body was still producing the hormone melatonin, which makes you sleepy. There are many ways that rainfall af fects human behaviour. Why do crime levels drop when the heavens open? How much does rain really affect people’s moods and behaviour?In 2008 university researcherspublished a paper proposing that weak summer mon...
Source: Guardian Unlimited Science - March 6, 2019 Category: Science Authors: Jamie Flook Tags: Science Source Type: news

Can You Really Catch Up on Lost Sleep? Here ’s What the Science Says
Experts have long said that you can’t make up for lost sleep by snoozing more on your days off. But in 2018, a study published in the Journal of Sleep Research called that conclusion into question, suggesting that sleeping in on days off could cancel out at least some of the health risks associated with work-week sleep deprivation, including the threat of early death. But a study recently published in Current Biology echoes previous convictions. It says extra weekend rest is not enough to make up for sleep lost during the week, and concludes that the “benefits of weekend recovery sleep are transient.” C...
Source: TIME: Health - March 4, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized sleep Source Type: news

Why melatonin is a powerful anticancer indolamine
(Natural News) A team of researchers from Iran suggests that melatonin has powerful anticancer properties. In their study, which was published in the journal Toxicology and Applied Pharmacology, they looked at the molecular anti-angiogenesis pathways mediated by melatonin and the responsible mechanisms in different forms of cancers both in vitro and in vivo. Melatonin is... (Source: NaturalNews.com)
Source: NaturalNews.com - February 27, 2019 Category: Consumer Health News Source Type: news

Diabetics can reduce their risk of depression by taking melatonin and quercetin
(Natural News) Diabetes is one of the most prevalent diseases in the world. Recent estimates by the World Health Organization show that there are more than 400 million people with this disease. This number is expected to become even bigger in the next few years unless people start doing something about it. Finding an effective treatment for diabetes should... (Source: NaturalNews.com)
Source: NaturalNews.com - February 25, 2019 Category: Consumer Health News Source Type: news

Acute stress disrupts temporal patterns of behavioral and biochemical parameters of rats - Souza A, Detanico BC, Medeiros LF, Oliveira C, Scarabelot VL, Cioato SG, Caumo W, Torres ILS.
This study aimed to answer these questions: (i) Can the temporal patterns of locomotor and exploratory activities and anxiety-like behavior be disrupted by a single session of stress? (ii) Can the temporal patterns of corticosterone, melatonin, and glucose... (Source: SafetyLit)
Source: SafetyLit - February 23, 2019 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Children With Autism More Than Twice As Likely To Have Trouble Sleeping
BOSTON (CBS) – According to a study in the journal Pediatrics, young children with autism have a harder time getting to sleep and staying asleep. Researchers examined the sleep habits of almost 2,000 kids between the ages of 2 and 5 and found that while about a quarter of the kids in the general population had sleep problems, kids on the autism spectrum and those with other developmental delays with characteristics of autism were more than twice as likely to have sleep problems. Children with autism often have anxiety, difficulty making transitions and differences in melatonin production, all of which may contribute....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 11, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Autism Dr. Mallika Marshall Sleep Source Type: news

Medical News Today: Which foods can help you sleep?
A variety of foods contain compounds that can help a person sleep, such as serotonin, melatonin, and tryptophan. Learn about the best foods for falling and staying asleep here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 25, 2019 Category: Consumer Health News Tags: Sleep / Sleep Disorders / Insomnia Source Type: news

Experts warn against regular use of melatonin
Concerns over safety have prompted the American Chemical Society to produce a video that indicates melatonin should be used only as a last resort for sleep regulation.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 21, 2018 Category: Endocrinology Source Type: news

Melatonin'Should Be a Last Resort' in Tackling Sleep Issues Melatonin'Should Be a Last Resort' in Tackling Sleep Issues
Individuals with disturbed sleep patterns should look at light exposure and sleep behaviors before reaching for melatonin, say experts who suggest a series of recommendations for taking the hormone.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 20, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway - Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J.
In this study, using a weight-drop model of TBI, we investiga... (Source: SafetyLit)
Source: SafetyLit - December 19, 2018 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Guidelines on melatonin usage
Chronic administration of melatonin should be restricted to nighttime and doses tailored to the patient, according to new guidelines published inEndocrine Reviews.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 12, 2018 Category: Endocrinology Source Type: news

Researchers propose guidelines for the therapeutic use of melatonin
(Funda ç ã o de Amparo à Pesquisa do Estado de S ã o Paulo) In an article published in Endocrine Reviews, Brazilian professors discuss the general criteria to be considered when prescribing the pineal hormone as a health supplement. The guidelines will help health professionals to analyze, understand and interpret the effects of melatonin. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 11, 2018 Category: International Medicine & Public Health Source Type: news

Look Up From Your Screen
One of the best things about being in the emergency services is the freedom we enjoy from a traditional office setting. Increasingly, though, our mobile devices are infiltrating our space and chewing up our time and attention. We can be sitting in the cab of an emergency vehicle anywhere, but still be tethered by our phone and tablets, unless we make a conscious choice not to be ruled by techno-diversions. As a member of the healthcare world, why not set an example to others and choose to heed the advice of experts to look up from the screens to which we all seem addicted? Here are three good reasons: 1. ...
Source: JEMS Special Topics - December 4, 2018 Category: Emergency Medicine Authors: Kate Dernocoeur, NREMT Tags: Exclusive Articles Columns Operations Source Type: news

Arrestin activity during light exposure linked to regulation of melatonin
Research, published inCell Reports, suggests that arrestins allow melanopsin in the rentina to regenerate during exposure to light, affecting melatonin levels and the circadian rhythm.  Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - November 28, 2018 Category: Endocrinology Source Type: news

Medical News Today: Is melatonin safe for children?
Melatonin supplements are a popular treatment for children with sleeping problems. Although some research suggests that melatonin may be safe and effective for children, there are no clear guidelines on a suitable dosage. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 27, 2018 Category: Consumer Health News Tags: Pediatrics / Children's Health Source Type: news

As Melatonin Use Rises, So Do Safety Concerns As Melatonin Use Rises, So Do Safety Concerns
Although the use of melatonin offers benefits, calls to poison centers about melatonin have increased, and it can make some drugs less effective, including antihypertensive medications.WebMD Health News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 13, 2018 Category: Consumer Health News Tags: Family Medicine/Primary Care News Source Type: news

As Melatonin Use Rises, So Do Safety Concerns
One review of 15 studies involving 284 otherwise healthy subjects found that those who took melatonin before bed fell asleep 3.9 minutes faster on average and slept 13 minutes longer. Another, of 19 studies involving 1,700 people, found that melatonin users fell asleep 7 minutes faster on average and slept 8 minutes longer. (Source: WebMD Health)
Source: WebMD Health - November 12, 2018 Category: Consumer Health News Source Type: news

Natural supplements that treat sleep disruptions and menopause symptoms
(Natural News) There are a lot of things that a person can do to improve sleep during menopause. Some examples include dietary changes, exercise, stress management, and mind-body therapies. However, natural supplements are also effective in treating these unpleasant symptoms. (h/t PsychologyToday.com) Melatonin: Melatonin isn’t just for making a person sleep better. It can also improve... (Source: NaturalNews.com)
Source: NaturalNews.com - November 5, 2018 Category: Consumer Health News Source Type: news

Melatonin: the body's natural sleep-promoting hormone
Prescriptions for short periods are considered safe, but there is little research into the long-term effectsIn daylight hours there is so little melatonin in the bloodstream that it is barely detectable. But when the sun goes down, the eyes sense the failing light, and part of the hippocampus signals the pineal gland, a pea-sized lump of tissue near the centre of the brain, to ramp up production of the sleep-promoting hormone. Levels of melatonin rise sharply from 9pm, inducing feelings of sleepiness, and remain high until the following morning.Much of the research on prescribing melatonin for children with sleep problems ...
Source: Guardian Unlimited Science - November 2, 2018 Category: Science Authors: Ian Sample Tags: Science Sleep Child protection Health & wellbeing Children Social care Society UK news Source Type: news

Is My Teenager Depressed or Just Moody? 8 Questions to Consider Before Getting Help
Teenagers are supposed to be moody, right? One moment they are happy and laughing about a silly Youtube video and the next they are slamming their door to their room and crying into their pillow.  You tell yourself “Its just hormones,” and try to brush it off. Chances are you are right. Most teenagers do fluctuate in mood to some extent and that is normal. I have a friend who even nicknamed her teen the “Threen-ager” because her daughter resorted to teen meltdowns when she didn’t get her way. But how do you know if your teen is just moody or if he or she is depressed or even anxious? Kno...
Source: Psych Central - October 5, 2018 Category: Psychiatry Authors: Amy Topelson, MA, MA, LPC, NCC Tags: Children and Teens Depression Parenting School Issues Students Suicide Source Type: news

Melatonin may reduce diabetes risk in men
According to a study, published inClinical Endocrinology, higher levels of melatonin are associated with a reduced incidence of type-2 diabetes in men.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 24, 2018 Category: Endocrinology Source Type: news

The Scientific Secrets to Preventing Jet Lag
Traveling abroad can be exhilarating. But sometimes it’s easy to discount the crippling jet leg that can set in after traversing multiple time zones—leaving you exhausted, disoriented and possibly causing you to miss out on your vacation. Jet lag is “something that can ruin a vacation or plague athletes and musicians or have a businessman or woman not perform at their peak,” explains Charmane Eastman, a professor in the Department of Behavioral Sciences and the founding director of the Biological Rhythms Research Laboratory at Rush University Medical Center in Chicago. The number of passengers flyin...
Source: TIME: Health - September 18, 2018 Category: Consumer Health News Authors: Melissa Locker Tags: Uncategorized health jet lag Living sleep Travel Source Type: news

Charity calls on the NHS to give all children with cancer a £1 jetlag supplement
Children with Cancer UK is urging the health service to provide melatonin on top of youngsters' existing chemo or radiotherapy. The supplement also eases chemo's side effects. (Source: the Mail online | Health)
Source: the Mail online | Health - September 14, 2018 Category: Consumer Health News Source Type: news

Experts say that children exposed to bright light at night may develop health complications as adults
(Natural News) Using bright lights at night in your home can be harmful to your children. A study published in the journal Physiological Reports found that exposing preschool children to bright electric light at night hampers melatonin production completely. Melatonin is a hormone essential for healthy circadian rhythms and good sleep; the suppression of melatonin... (Source: NaturalNews.com)
Source: NaturalNews.com - September 5, 2018 Category: Consumer Health News Source Type: news

Melatonin meets diabetes
(Source: ScienceNOW)
Source: ScienceNOW - August 30, 2018 Category: Science Authors: Foley, J. F. Tags: twis Source Type: news

Type 2 diabetes-associated variants of the MT2 melatonin receptor affect distinct modes of signaling
Melatonin is produced during the night and regulates sleep and circadian rhythms. Loss-of-function variants in MTNR1B, which encodes the melatonin receptor MT2, a G protein–coupled receptor (GPCR), are associated with an increased risk of type 2 diabetes (T2D). To identify specific T2D-associated signaling pathway(s), we profiled the signaling output of 40 MT2 variants by monitoring spontaneous (ligand-independent) and melatonin-induced activation of multiple signaling effectors. Genetic association analysis showed that defects in the melatonin-induced activation of Gαi1 and Gαz proteins and in spontaneou...
Source: Signal Transduction Knowledge Environment - August 28, 2018 Category: Science Authors: Karamitri, A., Plouffe, B., Bonnefond, A., Chen, M., Gallion, J., Guillaume, J.-L., Hegron, A., Boissel, M., Canouil, M., Langenberg, C., Wareham, N. J., Le Gouill, C., Lukasheva, V., Lichtarge, O., Froguel, P., Bouvier, M., Jockers, R. Tags: STKE Research Articles Source Type: news

What is the Difference Between Nightmares and Night Terrors?
Discussion Sleep disorders are common in all ages particularly with sleep deprivation in our increasingly busy world. Sleep problems are more common in patients with attention deficit hyperactivity disorder, epilepsy, headache and visual impairments. Sleep problems can cause cognitive and behavioral impairments including emotional regulation problems, increased seizures or headaches, and impaired attention and have been known to prolong recovery from various acquired brain injuries. Parasomnias are “undesirable events that accompany sleep and typically occur during sleep-wake transitions.” The term sleep terr...
Source: PediatricEducation.org - August 27, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Plant-based melatonin found to be a viable, contaminant-free alternative to synthetically made varieties
(Natural News) Spanish scientists are asking the medical industry to take a closer look at plant-based melatonin for improving sleep and cognitive function. In a recently published botanical review, study authors state that phytomelatonin surpasses many animal-based or synthetic forms of the hormone and can be used as a nutraceutical compound. The 100 percent natural... (Source: NaturalNews.com)
Source: NaturalNews.com - August 1, 2018 Category: Consumer Health News Source Type: news

Company led recall: Melatonin 10mg capsules
The Medicines and Healthcare products Regulatory Agency (MHRA) has issued a company led recall for specific batches of Melatonin 10mg capsules (IPS Specials). (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - July 17, 2018 Category: Drugs & Pharmacology Source Type: news

A gene linked to job-related exhaustion in shift workers increases the risk of Alzheimer's
(University of Helsinki) A new study shows that a variation in the melatonin receptor 1A gene is linked to the risk of Alzheimer's disease in the elderly. The same research team has previously demonstrated that the same genetic variation reduces tolerance to shift work among the working age population. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 6, 2018 Category: International Medicine & Public Health Source Type: news

Effect of Ramelteon on Duration of ICU Stay Effect of Ramelteon on Duration of ICU Stay
Might prophylactic administration of melatonin or melatonin agonists shorten the duration of ICU stay and improve outcomes in critically ill patients?Critical Care Medicine (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 5, 2018 Category: Consumer Health News Tags: Critical Care Journal Article Source Type: news

Anti-mucositis gel developed at UGR to be widely available by 2022
(University of Granada) Researchers from the University of Granada have developed new medication which could help to treat and prevent chemotherapy and radiotherapy-induced oral mucositis in head and neck cancer patients. The melatonin compound, in the form of a gel, has now passed phases 1 and 2 of clinical trials and is expected to be on sale by 2022. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2018 Category: International Medicine & Public Health Source Type: news

Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors
Neuromodulatory systems exert profound influences on brain function. Understanding how these systems modify the operating mode of target circuits requires spatiotemporally precise measurement of neuromodulator release. We developed dLight1, an intensity-based genetically encoded dopamine indicator, to enable optical recording of dopamine dynamics with high spatiotemporal resolution in behaving mice. We demonstrated the utility of dLight1 by imaging dopamine dynamics simultaneously with pharmacological manipulation, electrophysiological or optogenetic stimulation, and calcium imaging of local neuronal activity. dLight1 enab...
Source: ScienceNOW - June 28, 2018 Category: Science Authors: Patriarchi, T., Cho, J. R., Merten, K., Howe, M. W., Marley, A., Xiong, W.-H., Folk, R. W., Broussard, G. J., Liang, R., Jang, M. J., Zhong, H., Dombeck, D., von Zastrow, M., Nimmerjahn, A., Gradinaru, V., Williams, J. T., Tian, L. Tags: Neuroscience, Online Only r-articles Source Type: news

A melatonin-fueled drink to help you sleep: What a nutritionist says about the trend
Som Sleep contains melatonin, magnesium, vitamin B6, GABA and L-theanine. (Source: ABC News: Health)
Source: ABC News: Health - June 25, 2018 Category: Consumer Health News Tags: GMA Source Type: news

Melatonin PROVEN to have anti-obesity effects
(Natural News) Melatonin has been getting a lot of attention as a natural sleeping aid, but researchers from several universities now reveal it can also help in limiting weight gain. In a study on rats, they proved that the long-term administration of melatonin could increase the body’s capability to use up calories and burn away... (Source: NaturalNews.com)
Source: NaturalNews.com - June 20, 2018 Category: Consumer Health News Source Type: news

A Third of Children Use Dietary Supplements. Here ’s Why Researchers Say That’s Concerning
A third of kids and adolescents under age 19 regularly take supplements like omega-3 fatty acids, multivitamins and melatonin, according to a new report. It’s a finding that researchers say is concerning because there is no proven benefit for healthy children taking supplements. The report, published Monday as a research letter in the journal JAMA Pediatrics, found that overall about a third of the young people surveyed used dietary supplements, with multivitamins being the most common. Use of supplements that primarily contained vitamins and minerals remained stable over time, but use of herbal, non-vitamin, or non-...
Source: TIME: Health - June 18, 2018 Category: Consumer Health News Authors: Alexandra Sifferlin Tags: Uncategorized healthytime medicine onetime Vitamins Source Type: news

A Third of Children Use Alternative Medicines
Multivitamins were the most common supplements, followed by vitamin C, omega-3 fatty acids, vitamin D and melatonin. (Source: NYT Health)
Source: NYT Health - June 18, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Vitamins Omega-3 Fatty Acids Oils and Fats Melatonin (Hormone) Vitamin D Vitamin C Alternative and Complementary Medicine Children and Childhood Source Type: news

Melatonin Gel May Reduce Oral Mucositis From Chemo, Radiation Melatonin Gel May Reduce Oral Mucositis From Chemo, Radiation
Data from a phase II trial of Mucomel (3% melatonin gel) suggest the formulation may reduce the risk of oral mucositis resulting from chemo and radiotherapy for head and neck cancers.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 6, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Your Tablet and Smartphone Is Ruining Your Sleep
It wasn't just that light from electronic devices suppressed their secretion of melatonin, the sleep-regulating hormone, study author Jeanne Duffy said. Researchers expected that based on other studies. (Source: WebMD Health)
Source: WebMD Health - May 25, 2018 Category: Consumer Health News Source Type: news

How Nighttime Tablet and Phone Use Disturbs Sleep
When a person used an iPad instead of reading print before bedtime, he or she had a later sleep onset and suppressed levels of melatonin. (Source: NYT Health)
Source: NYT Health - May 23, 2018 Category: Consumer Health News Authors: NICHOLAS BAKALAR Tags: Tablet Computers Sleep iPad Melatonin (Hormone) Source Type: news

Evening use of light-emitting tablets may disrupt healthy sleep
(Wiley) A new Physiological Reports study reveals that evening use of light-emitting tablets can induce delays in desired bedtimes, suppress secretion of melatonin (the hormone that regulates sleep and wakefulness), and impair next-morning alertness. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 23, 2018 Category: International Medicine & Public Health Source Type: news

White Light Exposure Suppresses Melatonin Secretion in Many Blind People White Light Exposure Suppresses Melatonin Secretion in Many Blind People
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 18, 2018 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Scientists discover how melatonin keeps you awake
Research published inThe Journal of Pineal Research suggests that scientists have found how melatonin interacts with neurons to promote or impair sleep.Science Daily (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 16, 2018 Category: Endocrinology Source Type: news

13 Ways Being a Night Owl Could Hurt Your Health
This article originally appeared on Health.com (Source: TIME: Health)
Source: TIME: Health - May 15, 2018 Category: Consumer Health News Authors: Amanda MacMillan / Health.com Tags: Uncategorized healthytime onetime sleep Source Type: news

Melatonin can aid weight loss
According to a study, published in theJournal of Pineal Research, chronic administration of melatonin has anti-obesity effects, through a newly identified adipose-based mechanism.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - May 11, 2018 Category: Endocrinology Source Type: news

Jet-lag supplement melatonin may combat obesity
Researchers from the University of Grenada found melatonin increases the amount of fat rodents use as energy rather than it being stored, as well as lowering fat deposits around their abdomens. (Source: the Mail online | Health)
Source: the Mail online | Health - May 10, 2018 Category: Consumer Health News Source Type: news

Jet-lag supplement may combat obesity: Melatonin burns calories and reduces fat storage
Researchers from the University of Grenada found melatonin increases the amount of fat rodents use as energy rather than it being stored, as well as lowering fat deposits around their abdomens. (Source: the Mail online | Health)
Source: the Mail online | Health - May 10, 2018 Category: Consumer Health News Source Type: news

Melatonin for Migraine Headache Prophylaxis Melatonin for Migraine Headache Prophylaxis
Is melatonin effective for reducing the frequency of migraine headaches?Medscape Pharmacists (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 30, 2018 Category: Consumer Health News Tags: Pharmacist Ask the Expert Source Type: news