Astragalus and Ginseng Polysaccharides Improve Developmental, Intestinal Morphological, and Immune Functional Characters of Weaned Piglets

Conclusion In conclusion, dietary supplementation with Aps or Gps could improve the growth performance, liver function, and intestinal villus morphology, and may regulate host immune functioning by activating the TLR4-mediated MyD88-dependent signaling pathway, and also enhance the concentration of VFAs in the colon and increase the colonic microbial population and diversity in weaned piglets. Plant polysaccharides may regulate the final fermentation products and the number and diversity of bacteria in the colon to promote the healthy growth of piglets. Data Availability The raw data supporting the conclusions of this manuscript will be made available by the authors, without undue reservation, to any qualified researcher. Ethics Statement This study was carried out in accordance with the recommendations of the care and use of laboratory animals, Institutional Animal Care and Use Committee of Zhejiang Agricultural and Forestry University. The protocol was approved by the Ethics Committee of Zhejiang Agricultural and Forestry University, Hangzhou, China (SYXKzhe 2016-087). Author Contributions CY, QH, and GC designed the trials, performed the experiments, and edited the manuscript. KW and YX performed the samples detection. YX, KW, and JL analyzed the data. QH wrote the manuscript, which was edited by CY and GC. All authors read and approved the final manuscript. Funding The present research was supported by the Key Research Project of Zhejiang Province (No. 2017C02005...
Source: Frontiers in Physiology - Category: Physiology Source Type: research