To Switch or Not to Switch Anticoagulation?
Reference: Joosten LPT, et al. Safety of Switching From a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients With Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial. Circulation 2024;149(4):279 –289. https://doi.org/10.1161/circulationaha.123.066485. (Source: Caring for the Ages)
Source: Caring for the Ages - April 26, 2024 Category: Health Management Authors: Omid Salaami Tags: Pragmatic Research Source Type: news

Identification of a murder caused by brodifacoum poisoning based on clinical examinations and LC-MS/MS results - Yu Z, Zhao E, Shi Q, Yuan Y, Ma J, Zhou L, Duan Y, Zhou Y.
Brodifacoum exerts its antagonistic effect against the metabolism of vitamin K, an essential component in the synthesis of blood coagulation factors. This effect ultimately hinders the blood's capacity to clot effectively, rendering it a commonly employed ... (Source: SafetyLit)
Source: SafetyLit - March 6, 2024 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

8 common questions new parents ask about vitamin K
Vitamin K is a nutrient that helps blood clot or stop bleeding. Most adults get vitamin K from their food. Bacteria in the large intestines also make some vitamin K that the body can absorb. Healthcare professionals recommend all babies receive a vitamin K injection at birth to help their blood clot effectively. New parents often have questions about these preventive measures for newborns, which also may include  screenings for genetic conditions and antibiotic eye ointment to… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 5, 2024 Category: Databases & Libraries Source Type: news

An attempted homicidal poisoning with bromadialone - McCulloch KJ, Chen Y, Gau JP, Yang CC, Isoardi KZ.
Bromadiolone, a second-generation anticoagulant rodenticide, has a long half-life [Citation1,Citation2]. It is a vitamin K antagonist, inhibiting the synthesis of factors II, VII, IX, X, proteins C, S, and Z [Citation3]. Poisoning causes protracted coag... (Source: SafetyLit)
Source: SafetyLit - January 29, 2024 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Alteplase Not Harmful in NOAC Users, Even in a More Bleeding-Prone Cohort
(MedPage Today) -- Stroke patients treated with intravenous alteplase (Activase) did not have more intracranial hemorrhages if they had recently taken non-vitamin K antagonist oral anticoagulants (NOACs), according to an Asian cohort study that... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 20, 2023 Category: Cardiology Source Type: news

How Late Can You Give Routine Newborn Care?
Discussion Routine newborn screening and treatment is focused on assisting the infant’s transition to extrauterine life, screening for health problems that may or may not be easily identifiable, and preventing acute or chronic health problems. Healthy infants begin with healthy pregnancies including risk factor assessment and screening of mothers. Such routine maternal screening and treatment does or may include glucose tolerance tests, ultrasound examinations, screenings for maternal blood type (with appropriate administration of Rho(D) immunoglobulin if appropriate), Hepatitis B, Neisseria gonorrhea, Chlamydia, Cyt...
Source: PediatricEducation.org - November 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

How Late Can You Give Routine Newborn Care?
Discussion Routine newborn screening and treatment is focused on assisting the infant’s transition to extrauterine life, screening for health problems that may or may not be easily identifiable, and preventing acute or chronic health problems. Healthy infants begin with healthy pregnancies including risk factor assessment and screening of mothers. Such routine maternal screening and treatment does or may include glucose tolerance tests, ultrasound examinations, screenings for maternal blood type (with appropriate administration of Rho(D) immunoglobulin if appropriate), Hepatitis B, Neisseria gonorrhea, Chlamydia, Cyt...
Source: PediatricEducation.org - November 20, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

AHA: Avoidance of Aspirin Noninferior With LVAD in Advanced Heart Failure
THURSDAY, Nov. 16, 2023 -- Avoidance of aspirin as part of an antithrombotic regimen that includes a vitamin K agonist (VKA) is noninferior to an aspirin-containing regimen for patients with advanced heart failure receiving support from a fully... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 16, 2023 Category: Pharmaceuticals Source Type: news

Dropping Aspirin Cuts Bleeding in LVAD Patients Dropping Aspirin Cuts Bleeding in LVAD Patients
A randomized trial evaluating vitamin K therapy with aspirin or placebo with a left ventricular assist device shows avoiding aspirin reduced bleeding without increasing thrombotic risk.Medscape Medical News (Source: Medscape Transplantation Headlines)
Source: Medscape Transplantation Headlines - November 13, 2023 Category: Transplant Surgery Tags: Cardiology News Source Type: news

Dropping Aspirin Cuts Bleeding in LVAD Patients Dropping Aspirin Cuts Bleeding in LVAD Patients
A randomized trial evaluating vitamin K therapy with aspirin or placebo with a left ventricular assist device shows avoiding aspirin reduced bleeding without increasing thrombotic risk.MDedge News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - November 13, 2023 Category: Internal Medicine Tags: Cardiology News Source Type: news

A vitamin K
Whether you snag some vitamin C at the first sign of a cold or stock up on probiotics to keep your gut health in check, you’re not alone in turning to dietary supplements—an estimated 75% of Americans use them. Among the various types, vitamin K is gaining popularity due to its potential benefits…#vitamink #viola #fortune #vitamink3 #oncologyletters #k2 #canola #vitamink2 #vitamink1 #crohn (Source: Reuters: Health)
Source: Reuters: Health - November 4, 2023 Category: Consumer Health News Source Type: news

Don't Assume Newer Is Better for All -- Randomize: FRAIL-AF Don't Assume Newer Is Better for All -- Randomize: FRAIL-AF
John Mandrola interviews the FRAIL-AF researchers who tested whether switching from a vitamin K antagonist to a direct-acting oral anticoagulant was safe in frail older adults with atrial fibrillation.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 25, 2023 Category: Cardiology Tags: Cardiology Commentary Source Type: news

VKA Therapy Beats Switch to NOAC in Frail AF Patients VKA Therapy Beats Switch to NOAC in Frail AF Patients
Frail patients with atrial fibrillation who were switched to a newer NOAC agent had more bleeding than those left on older vitamin K antagonists, without any benefit in terms of thromboembolic events.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 11, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Big Cholesterol Lie Won ’ t Die
I’ve been warning my patients and readers like you about Big Pharma’s cholesterol scam for more than two decades. But my message continues to get lost in the unrelenting Big Lie presented by so-called experts in the FDA, AHA, and USDA. Now, a new study confirms — once again — that there is no link whatsoever between what’s known as “bad” cholesterol and death as a result of heart disease in individuals over 60 years of age.1 In fact, the study found that 92% of people with high cholesterol actually lived longer. You see, there is no such thing as “good” or “bad” cholesterol. You need both to stay heal...
Source: Al Sears, MD Natural Remedies - August 28, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Heart Health Source Type: news

Rush to DOACs Spells Trouble for Frail Warfarin Users
(MedPage Today) -- AMSTERDAM -- Best let frail older people who are stable on international normalized ratio (INR)-guided vitamin K antagonist (VKA) management stay on it instead of switching to a direct oral anticoagulant (DOAC or NOAC), the... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - August 28, 2023 Category: Cardiology Source Type: news