Abbott Wins Approval for CATALYST Trial for At-Risk Stroke Patients
This study is an extremely important step in assessing the Amplatzer Amulet as an effective non-prescription drug alternative for patients with AFib who are at an increased risk for ischemic stroke." In an email sent to MD+DI, Abbott wrote, “We already have an Amulet IDE trial underway that is intended to support our submission for approval in the U.S. for Amplatzer Amulet. The newly announced CATALYST trial will support our submission for an expanded indication for Amulet as a safe and effective alternative to NOAC drugs for patients with atrial fibrillation and at risk of stroke.”...
Source: MDDI - February 3, 2020 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Regulatory and Compliance Source Type: news

Abbott Announces First-of-Its-Kind Trial to Assess New Therapy Option for People at Risk of Stroke
- The CATALYST trial will examine Abbott's Amplatzer ™ Amulet™ device compared to non-vitamin K oral anticoagulants, the current standard in attempting to lower stroke and bleeding risks for patients with atrial fibrillation (Source: Abbott.com)
Source: Abbott.com - February 3, 2020 Category: Pharmaceuticals Source Type: news

Non-vitamin K Antagonist Oral Anticoagulants Beyond AF Non-vitamin K Antagonist Oral Anticoagulants Beyond AF
Several new studies are investigating the use of NOACs in other medical conditions beyond stroke prevention in AF and the prevention or treatment of VTE.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 29, 2020 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

Compared With Warfarin, Non-Vitamin K Antagonist Oral Anticoagulants May Better Limit Risks to Bone Health
No abstract available (Source: Lippincott's Bone and Joint Newsletter)
Source: Lippincott's Bone and Joint Newsletter - January 25, 2020 Category: Orthopaedics Tags: Trends and Innovations Source Type: news

Low vitamin K levels associated with disability and mobility limitations in the elderly
(Natural News) Vitamin K is an essential vitamin that plays a vital role in bone and heart health. It is one of the main vitamins responsible for blood coagulation and bone mineralization and also helps maintain brain function, boost metabolism, and protect against certain cancers. While vitamin K deficiency is rare, a lower-than-average intake of... (Source: NaturalNews.com)
Source: NaturalNews.com - January 23, 2020 Category: Consumer Health News Source Type: news

Keep your heart and bone health a-ok by increasing intake of vitamin K
(Natural News) A person’s risk of developing heart and bone diseases increases with age. Fortunately, there’s an effective and natural way of reducing this risk. Research suggests increasing your intake of vitamin K can improve your heart and bone health. According to an article published in Integrative Medicine: A Clinicians Journal, adequate vitamin K intake... (Source: NaturalNews.com)
Source: NaturalNews.com - December 29, 2019 Category: Consumer Health News Source Type: news

Older adults — particularly men — need to make sure they get enough vitamin K
Research shows that too little of the nutrient is associated with various age-related concerns, such as cognitive function, heart health and mobility. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - December 3, 2019 Category: Consumer Health News Authors: Consumer Reports Source Type: news

Audio reveals Illinois doctors planning to seize babies to give them vitamin K shots
Parents in Illinois claim that hospitals there temporarily seized their newborns after they refused a vitamin K shot and called on them to be investigated for neglect, a policy since rescinded. (Source: the Mail online | Health)
Source: the Mail online | Health - November 18, 2019 Category: Consumer Health News Source Type: news

Study Compares Anticoagulants for Antiphospholipid Syndrome
TUESDAY, Oct. 15, 2019 -- In thrombotic antiphospholipid antibody syndrome (APS), rivaroxaban is not noninferior to dose-adjusted vitamin K antagonists (VKAs), according to a study published online Oct. 15 in the Annals of Internal Medicine. Josep... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 15, 2019 Category: Pharmaceuticals Source Type: news

14.10.19: Not intended for U.S. and UK Media
U.S. FDA approves rivaroxaban to help prevent blood clots in acutely ill medical patientsA new oral option for patients in the U.S. with acute medical illnesses at risk for thromboembolic complications who are not at high risk of bleeding / Rivaroxaban is the only non vitamin K antagonist oral anticoagulant (NOAC) approved in the U.S for the continuum of venous thromboembolism (VTE) care, from prevention and treatment of initial VTE through extended prevention of recurrent VTEmehr ... (Source: Bayer IR Newsfeed: Events)
Source: Bayer IR Newsfeed: Events - October 14, 2019 Category: Pharmaceuticals Source Type: news

U.S. FDA approves rivaroxaban to help prevent blood clots in acutely ill medical patients (for specialized target groups only)
A new oral option for patients in the U.S. with acute medical illnesses at risk for thromboembolic complications who are not at high risk of bleeding / Rivaroxaban is the only non vitamin K antagonist oral anticoagulant (NOAC) approved in the U.S for the continuum of venous thromboembolism (VTE) care, from prevention and treatment of initial VTE through extended prevention of recurrent VTE (Source: Bayer Company News)
Source: Bayer Company News - October 14, 2019 Category: Pharmaceuticals Source Type: news

Dying to be ill: Munchausen meets warfarin overdose - Akella P, Jindal V, Maradana S, Siddiqui AD.
Patients with severe coagulopathy related to vitamin K deficient proteins can be associated with surreptitious ingestion of vitamin K antagonists. Our patient presented acutely with extensive ecchymosis, gingival bleeding and hematuria. Her initial PT and ... (Source: SafetyLit)
Source: SafetyLit - September 28, 2019 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

ENTRUST-AF PCI Supports Safety of Dual Therapy With Edoxaban ENTRUST-AF PCI Supports Safety of Dual Therapy With Edoxaban
ENTRUST AF-PCI completes the trials of NOACs in patients with AF who undergo PCI, showing dual therapy with edoxaban was noninferior to vitamin K-antagonist – based triple therapy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - September 19, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Non-Vitamin K Oral Anticoagulants May Be Best for Early-Stage CKD
TUESDAY, July 16, 2019 -- Non-vitamin K oral anticoagulants (NOACs) have a superior benefit-risk profile to that of vitamin K antagonists (VKAs) for patients with early-stage chronic kidney disease (CKD), according to a review published online July... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 16, 2019 Category: Pharmaceuticals Source Type: news

Anticoagulation Use prior to Common Dental Procedures: A Systematic Review.
Cardiol Res Pract. 2019 Jun 2;2019:9308631. doi: 10.1155/2019/9308631. eCollection 2019.AbstractCurrently, the number of patients on oral anticoagulation is increasing. There is a paucity of data regarding maintaining oral anticoagulation (especially novel oral anticoagulants) around the time of specific dental procedures. A dentist has three options: either to stop anticoagulation, to continue it, or to bridge with heparin. A systematic review of 10 clinical trials was conducted to address this issue. It was found that continuing anticoagulation during dental procedures did not increase the risk of bleeding in most trials...
Source: Dental Technology Blog - July 10, 2019 Category: Dentistry Source Type: news

08.07.19: Not intended for U.S. and UK Media - Important step towards improved treatment for children with venous thromboembolism
Rivaroxaban demonstrates strong efficacy and safety profile in phase III study in children with thromboembolismPhase III EINSTEIN-Jr. study in children concludes the largest pediatric thromboembolism program delivering results consistent with those in adults / Study shows a low risk of recurrent venous thromboembolism (VTE) in children treated with rivaroxaban compared with standard of care with low rates of bleeding / First phase III data on the use of a non-vitamin K oral anticoagulant (NOAC) in a large pediatric population / Study investigated a body weight-adjusted oral 20 mg equivalent dose of rivaroxaban for the prev...
Source: Bayer IR Newsfeed: Events - July 8, 2019 Category: Pharmaceuticals Source Type: news

Rivaroxaban demonstrates strong efficacy and safety profile in phase III study in children with thromboembolism (for specialized target groups only)
Phase III EINSTEIN-Jr. study in children concludes the largest pediatric thromboembolism program delivering results consistent with those in adults / Study shows a low risk of recurrent venous thromboembolism (VTE) in children treated with rivaroxaban compared with standard of care with low rates of bleeding / First phase III data on the use of a non-vitamin K oral anticoagulant (NOAC) in a large pediatric population / Study investigated a body weight-adjusted oral 20 mg equivalent dose of rivaroxaban for the prevention of recurrent VTE in children from birth to 17 years of age with confirmed VTE, including cerebral vein a...
Source: Bayer Company News - July 8, 2019 Category: Pharmaceuticals Source Type: news

Effect of vitamin K2 on postural sway in older people who fall: a randomized controlled trial - Witham MD, Price RJG, Band MM, Hannah MS, Fulton RL, Clarke CL, Donnan PT, McNamee P, Cvoro V, Soiza RL.
OBJECTIVES: Vitamin K is thought to be involved in both bone health and maintenance of neuromuscular function. We tested the effect of vitamin K2 supplementation on postural sway, falls, healthcare costs, and indices of physical function in older people at... (Source: SafetyLit)
Source: SafetyLit - June 24, 2019 Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news

Medical News Today: Low vitamin K may reduce mobility in older adults
Researchers found that older adults with vitamin K deficiency were more likely to develop mobility disability, such as difficulty walking and using stairs. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 14, 2019 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

Low vitamin K levels linked to mobility limitation and disability in older adults
(Tufts University, Health Sciences Campus) Tufts University researchers led the first study to evaluate the association between biomarkers of vitamin K status and mobility limitation and disability, and found older adults with low levels of circulating vitamin K were more likely to develop these conditions. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 13, 2019 Category: Biology Source Type: news

Study: Leafy Greens OK For People on Warfarin
The results of the small study suggest that taking in more vitamin K, not less, might help patients on warfarin (Coumadin). (Source: WebMD Health)
Source: WebMD Health - June 11, 2019 Category: Consumer Health News Source Type: news

Vitamin K Can Up Anticoagulation Stability in Patients on Warfarin
TUESDAY, June 11, 2019 -- Increasing vitamin K (VK) intake through dietary strategies improves the anticoagulation stability of warfarin-treated patients, according to a study presented during Nutrition 2019, the annual meeting of the American... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 11, 2019 Category: Pharmaceuticals Source Type: news

Study Refutes Notion That People on Warfarin Shouldn't Eat Leafy Greens
TUESDAY, June 11, 2019 -- Spinach-loving seniors, rejoice. A new study suggests that -- despite doctor warnings to the contrary -- you can eat leafy greens rich in vitamin K if you are taking the blood thinner warfarin. In fact, " I think all... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 11, 2019 Category: General Medicine Source Type: news

Management of rodenticide poisoning associated with synthetic cannabinoids - Godwin PO, Unterman S, Elfessi ZZ, Bhagat JD, Kolman K.
Synthetic cannabinoids may be adulterated with potent vitamin K antagonists, which should be considered if a patient presents with unexplained coagulopathy, widespread bleeding, and a history of synthetic cannabinoid use. Language: en... (Source: SafetyLit)
Source: SafetyLit - June 4, 2019 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Is Seaweed Healthy? Here ’s What Experts Say
Seaweed is a staple in many Asian cuisines, but many Americans still only encounter it when they go out for sushi. As a result, many diners don’t know what to make of it: Is seaweed healthy? Does it count as a vegetable? Are all kinds nutritionally the same? Miho Hatanaka, a Japanese-born registered dietitian who is based in Oregon, says the sea vegetable is worth getting to know. In the Japanese tradition, “people really attribute their health and longevity to seaweed, and even healthier skin and hair,” she says. Here’s what you need to know about eating seaweed. There are many types of edible sea...
Source: TIME: Health - April 30, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition Source Type: news

Medical News Today: What to know about vitamin K-2
Vitamin K has two main forms, K-1 and K-2. Vitamin K-2 is naturally present in fatty meats, dairy products, and fermented foods. Both forms of vitamin K are essential for blood clotting and bone health. However, vitamin K-2 may also protect against certain forms of cancer and heart disease. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - April 29, 2019 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

29.04.19: Not intended for U.S. and UK Media
Study reaffirms safety and efficacy profile of Xarelto™ for the prevention of stroke in patients with atrial fibrillationFirst results from RELOADED, an observational study in the EU, indicate that non-vitamin-K oral anticoagulants (NOACs) like Xarelto provide a benefit in renal preservation over time when compared to the vitamin-K antagonist (VKA) phenprocoumon / The data from the comparative effectiveness study in Germany confirm an improved safety outcome and comparable effectiveness for Xarelto compared with phenprocoumon in patients with non-valvular atrial fibrillation (NVAF), including those with renal insuffi...
Source: Bayer IR Newsfeed: Events - April 29, 2019 Category: Pharmaceuticals Source Type: news

Polypharmacy and Outcome in Patients on Vitamin K Antagonists Polypharmacy and Outcome in Patients on Vitamin K Antagonists
What impact does polypharmacy have on the quality and outcome of anticoagulation therapy with Vitamin K antagonists?Journal of the American Geriatrics Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 25, 2019 Category: Consumer Health News Tags: Internal Medicine Journal Article Source Type: news

Vitamins and Supplements Can ’t Replace a Balanced Diet, Study Says
Roughly 90% of American adults do not eat enough fruits and vegetables, but many are trying to make up for it by popping pills. According to the Council for Responsible Nutrition, 75% of U.S. adults take a dietary supplement of some kind. Multivitamins, many people believe, are a one-step way to get the nutrients they need. But new research published in the Annals of Internal Medicine suggests that vitamins and supplements may not be enough to keep you healthy. Nutrients consumed via supplements do not improve health and longevity as effectively as those consumed through foods, according to the study. While getting the rig...
Source: TIME: Health - April 8, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition Source Type: news

A short introduction to vitamin K deficiency
(Natural News) A person needs vitamins, so his or her body can grow healthy and strong. For the most part, many people strive to include vitamin-rich foods in their diet: A healthy meal usually has all the vitamins that your body needs in a day, which include: Vitamin A B-vitamins (thiamine, riboflavin, niacin, pantothenic acid, folate,... (Source: NaturalNews.com)
Source: NaturalNews.com - March 13, 2019 Category: Consumer Health News Source Type: news

XARELTO ® (rivaroxaban) Significantly Reduced Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation in Large, Real-World Meta-Analysis of Non-Vitamin K Antagonist Oral Anticoagulants (NOACs)
(Source: Johnson and Johnson)
Source: Johnson and Johnson - March 11, 2019 Category: Pharmaceuticals Source Type: news

Medical News Today: What to know about the warfarin diet
Warfarin is a blood thinner that can be more effective when restricting foods that are vitamin K-rich. Examples of these include broccoli and asparagus. Learn more about foods to avoid on the warfarin diet here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 12, 2019 Category: Consumer Health News Tags: Nutrition / Diet Source Type: news

What are the best food sources of vitamin K?
(Natural News) Following a healthy diet offers many benefits, such as improved overall physical and mental well-being. But did you know that eating foods rich in vitamin K can also boost your bone and heart health? Why is vitamin K important? The body needs vitamin K because it helps build and maintain healthy bones. This... (Source: NaturalNews.com)
Source: NaturalNews.com - February 3, 2019 Category: Consumer Health News Source Type: news

AF Guideline Update Prefers NOACs to Warfarin in Most Cases AF Guideline Update Prefers NOACs to Warfarin in Most Cases
More nuanced use of stroke-risk scores, percutaneous LAA occlusion, insights into AF complicating ACS, and ascendant non-vitamin-K oral anticoagulants top an AHA/ACC/HRS update to 2014 AF guidelines.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 31, 2019 Category: Consumer Health News Tags: Cardiology News Source Type: news

Doctors: Newer Blood Thinners Best Against A-Fib
The newer drugs are called non-vitamin K oral anticoagulants (NOACs). Examples include dabigatran (Pradaxa), rivaroxaban (Xarelto) and apixaban (Eliquis). (Source: WebMD Health)
Source: WebMD Health - January 28, 2019 Category: Consumer Health News Source Type: news

Prothrombin Complex Concentrates for Anticoagulant Reversal Prothrombin Complex Concentrates for Anticoagulant Reversal
This paper reviews the current evidence on prothrombin complex concentrate treatment for vitamin K antagonist reversal in the perioperative setting.Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 13, 2018 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Brussels sprouts could cut your risk of cancer  
An average 80g serving (roughly five sprouts) provides more vitamin C than an orange, all your vitamin K needs (good for wound healing), and more fibre than a slice of brown bread. (Source: the Mail online | Health)
Source: the Mail online | Health - December 10, 2018 Category: Consumer Health News Source Type: news

Stop throwing away one of the best parts of your Kale
(Natural News) Many health experts consider kale, a dark leafy green vegetable in the cabbage family, as a superfood, given its impressive vitamin, mineral, and antioxidant profile. As a natural source of potassium, it helps fight heart disease. With its iron properties, it assists with healthy muscle function and the transfer of oxygen between cells. Its Vitamin K... (Source: NaturalNews.com)
Source: NaturalNews.com - November 21, 2018 Category: Consumer Health News Source Type: news

Neuroene Therapeutics awarded $1.5 million to develop anti-seizure compound for epilepsy
(Medical University of South Carolina) Neuroene Therapeutics LLC, a start-up company founded by Medical University of South Carolina researchers, will optimize vitamin K analogues that have shown promise for improving seizure control in preclinical models of drug-resistant epilepsy with funding from a $1.5 million NIH Phase II Small Business Innovation Research grant. The vitamin K analogues improve seizure control by supporting mitochondrial health in brain cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 29, 2018 Category: International Medicine & Public Health Source Type: news

12.10.18: Not intended for U.S. and UK Media
U.S. FDA approves Bayer's Xarelto® for patients with coronary or peripheral artery diseaseXarelto, in combination with aspirin, is indicated to reduce the risk of major cardiovascular events in patients with chronic coronary artery disease or peripheral artery disease / Xarelto, in combination with aspirin, is the only non-vitamin K antagonist oral anticoagulant (NOAC) indicated for this patient group / Approval in the U.S. follows regulatory clearance in both Europe and Canadamehr ... (Source: Bayer IR Newsfeed: Events)
Source: Bayer IR Newsfeed: Events - October 12, 2018 Category: Pharmaceuticals Source Type: news

U.S. FDA approves Bayer & #8217;s Xarelto ® for patients with coronary or peripheral artery disease (for specialized target groups only)
Xarelto, in combination with aspirin, is indicated to reduce the risk of major cardiovascular events in patients with chronic coronary artery disease or peripheral artery disease / Xarelto, in combination with aspirin, is the only non-vitamin K antagonist oral anticoagulant (NOAC) indicated for this patient group / Approval in the U.S. follows regulatory clearance in both Europe and Canada (Source: Bayer Company News)
Source: Bayer Company News - October 12, 2018 Category: Pharmaceuticals Source Type: news

Vitamin K2 Steps Into the Spotlight for Bone and Heart Health Vitamin K2 Steps Into the Spotlight for Bone and Heart Health
When it comes to osteoporosis and cardiovascular disease, this unassuming variant of vitamin K may have a lot to offer.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 10, 2018 Category: Consumer Health News Tags: Public Health & Prevention Article Source Type: news

Anticoagulation for people with cancer and central venous catheters
This review found moderate-certainty evidence that LMWH reduces catheter ‐related venous thromboembolism (CR-VTE); evidence was inconclusive for LMWH effects on mortality and effects of vitamin K antagonists (VKA) on mortality or CR-VTE, and for LMWH versus VKA. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - September 28, 2018 Category: Consumer Health News Source Type: news

Why Whole-Fat Milk and Yogurt Are Healthier Than You Think
For years, experts have recommended low-fat dairy products over the full-fat versions, which are higher in calories and contain more saturated fat. Recent research, however, indicates that full-fat dairy may actually be healthier than its reputation suggests, and that people who eat full-fat dairy are not more likely to develop cardiovascular disease and type 2 diabetes than people who consume low-fat dairy. They may even be less likely to gain weight. Now, new research published Tuesday in The Lancet, adds to that body of evidence. The research suggests that eating dairy products of all kinds is associated with a lower ri...
Source: TIME: Health - September 12, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition healthytime Source Type: news

Children and teens who supplement with vitamin K have a reduced risk of fractures
(Natural News) Researchers have discovered a new approach to make the bones of children and teenagers stronger. A pilot study from Poland, the U.S., and the Netherlands, which was published in the journal Nutrients, revealed that children and teenagers who consume more vitamin K were less likely to experience bone fractures. In the study, the... (Source: NaturalNews.com)
Source: NaturalNews.com - September 5, 2018 Category: Consumer Health News Source Type: news

24.08.18: Not intended for U.S. and UK Media
Bayer secures approval in the EU for Xarelto® (rivaroxaban) for patients with coronary or peripheral artery diseaseXarelto is the only non-vitamin K antagonist oral anticoagulant (NOAC) indicated in combination with acetylsalicylic acid (ASA) for the prevention of atherothrombotic events in patients with coronary artery disease or symptomatic peripheral artery disease at high risk for ischemic events / Launch first expected in Germanymehr ... (Source: Bayer IR Newsfeed: Events)
Source: Bayer IR Newsfeed: Events - August 24, 2018 Category: Pharmaceuticals Source Type: news

Bayer secures approval in the EU for Xarelto ® (rivaroxaban) for patients with coronary or peripheral artery disease (for specialized target groups only)
Xarelto is the only non-vitamin K antagonist oral anticoagulant (NOAC) indicated in combination with acetylsalicylic acid (ASA) for the prevention of atherothrombotic events in patients with coronary artery disease or symptomatic peripheral artery disease at high risk for ischemic events / Launch first expected in Germany (Source: Bayer Company News)
Source: Bayer Company News - August 24, 2018 Category: Pharmaceuticals Source Type: news