< em > Streptomyces pyxinae < /em > sp. nov. and < em > Streptomyces pyxinicus < /em > sp. nov. isolated from lichen < em > Pyxine cocoes < /em > (Sw.) Nyl
Int J Syst Evol Microbiol. 2024 May;74(5). doi: 10.1099/ijsem.0.006364.ABSTRACTTwo novel actinobacteria, designated as LP05-1T and LP11T, were isolated from the lichen Pyxine cocoes (Sw.) Nyl. collected in Bangkok, Thailand. Genotypic and phenotypic analyses revealed that both strains represented members of the genus Streptomyces. The 16S rRNA gene of LP05-1T showed the highest similarity to the genome of Streptomyces gelaticus (98.41 %), while the 16S rRNA gene of LP11T was most similar to that of Streptomyces cinerochromogenes (98.93 %). The major menaquinones in LP05-1T were MK-9(H8), MK-9(H6), MK-9(H4) and MK-9(H2), an...
Source: International Journal of Systematic and Evolutionary Microbiology - May 7, 2024 Category: Microbiology Authors: Achiraya Somphong Wetchasart Polyiam Chanwit Suriyachadkun Paranee Sripreechasak Enjuro Harunari Yasuhiro Igarashi Somboon Tanasupawat Wongsakorn Phongsopitanun Source Type: research
Sa1577 THE ROLE OF INTRAVENOUS VITAMIN K IN THE CORRECTION OF CIRRHOSIS-ASSOCIATED COAGULOPATHY.
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Hila Shaim, Kian Abdul-Baki, Jordan C. Malone, Anni Chowdhury, Edward Butt, Moe Ameri, Daniel Shofner, Marissa Lee, Milee Patel, Pooja Bhakta, Michael Antony, Peter McCaffrey, Sean Yates Tags: AASLD Abstracts Source Type: research
In older patients with AF and frailty, switching from VKA to NOAC therapy increased a composite of major or CRNM bleeding at 12 mo
Ann Intern Med. 2024 May 7. doi: 10.7326/J24-0024. Online ahead of print.ABSTRACTJoosten LP, van Doorn S, van de Ven PM, et al. Safety of switching from a vitamin K antagonist to a non-vitamin K antagonist oral anticoagulant in frail older patients with atrial fibrillation: results of the FRAIL-AF randomized controlled trial. Circulation. 2024;149:279-289. 37634130.PMID:38710082 | DOI:10.7326/J24-0024 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - May 6, 2024 Category: Internal Medicine Authors: Andrew Dunn Source Type: research
< em > Microbacterium salsuginis < /em > sp. nov., a halotolerant actinobacterium with antimicrobial activity
Int J Syst Evol Microbiol. 2024 May;74(5). doi: 10.1099/ijsem.0.006362.ABSTRACTA novel Gram-staining-positive actinobacterium with antimicrobial activity, designated CFH 90308T, was isolated from the sediment of a salt lake in Yuncheng, Shanxi, south-western China. The isolate exhibited the highest 16S rRNA gene sequence similarities to Microbacterium yannicii G72T, Microbacterium hominis NBRC 15708T and Microbacterium xylanilyticum S3-ET (98.5, 98.4 and 98.2 %, respectively), and formed a separate clade with M. xylanilyticum S3-ET in phylogenetic trees. The strain grew at 15-40 ºC, pH 6.0-8.0 and could tolerate NaCl up t...
Source: International Journal of Systematic and Evolutionary Microbiology - May 2, 2024 Category: Microbiology Authors: Qingyang Su Yuwei Liu Tingting Xia Shuanglong Wei Caixia Cui Zhao Zhang Xudong Liu Guoxing Nie Hong Ming Source Type: research
< em > Microbacterium salsuginis < /em > sp. nov., a halotolerant actinobacterium with antimicrobial activity
Int J Syst Evol Microbiol. 2024 May;74(5). doi: 10.1099/ijsem.0.006362.ABSTRACTA novel Gram-staining-positive actinobacterium with antimicrobial activity, designated CFH 90308T, was isolated from the sediment of a salt lake in Yuncheng, Shanxi, south-western China. The isolate exhibited the highest 16S rRNA gene sequence similarities to Microbacterium yannicii G72T, Microbacterium hominis NBRC 15708T and Microbacterium xylanilyticum S3-ET (98.5, 98.4 and 98.2 %, respectively), and formed a separate clade with M. xylanilyticum S3-ET in phylogenetic trees. The strain grew at 15-40 ºC, pH 6.0-8.0 and could tolerate NaCl up t...
Source: International Journal of Systematic and Evolutionary Microbiology - May 2, 2024 Category: Microbiology Authors: Qingyang Su Yuwei Liu Tingting Xia Shuanglong Wei Caixia Cui Zhao Zhang Xudong Liu Guoxing Nie Hong Ming Source Type: research
Jeotgalibacillus haloalkalitolerans sp. nov., a novel alkalitolerant and halotolerant bacterium, isolated from the confluence of the Fenhe River and the Yellow River
Antonie Van Leeuwenhoek. 2024 May 1;117(1):74. doi: 10.1007/s10482-024-01968-8.ABSTRACTA Gram-stain positive, aerobic, alkalitolerant and halotolerant bacterium, designated HH7-29 T, was isolated from the confluence of the Fenhe River and the Yellow River in Shanxi Province, PR China. Growth occurred at pH 6.0-12.0 (optimum, pH 8.0-8.5) and 15-40℃ (optimum, 32℃) with 0.5-24% NaCl (optimum, 2-9%). The predominant fatty acids (> 10.0%) were iso-C15:0 and anteiso-C15:0. The major menaquinones were MK-7 and MK-8. The polar lipids were phosphatidylglycerol, diphosphatidylglycerol and two unidentified phospholipids. Phylo...
Source: Antonie van Leeuwenhoek - May 1, 2024 Category: Microbiology Authors: Ya-Fei Zhang Yun-Lin Peng Yong-Hui Xiao Bing Yu Ming-Yue Cao Zhi-Ling Zhang Le-Qun Huang Yi Li Source Type: research
Jeotgalibacillus haloalkalitolerans sp. nov., a novel alkalitolerant and halotolerant bacterium, isolated from the confluence of the Fenhe River and the Yellow River
Antonie Van Leeuwenhoek. 2024 May 1;117(1):74. doi: 10.1007/s10482-024-01968-8.ABSTRACTA Gram-stain positive, aerobic, alkalitolerant and halotolerant bacterium, designated HH7-29 T, was isolated from the confluence of the Fenhe River and the Yellow River in Shanxi Province, PR China. Growth occurred at pH 6.0-12.0 (optimum, pH 8.0-8.5) and 15-40℃ (optimum, 32℃) with 0.5-24% NaCl (optimum, 2-9%). The predominant fatty acids (> 10.0%) were iso-C15:0 and anteiso-C15:0. The major menaquinones were MK-7 and MK-8. The polar lipids were phosphatidylglycerol, diphosphatidylglycerol and two unidentified phospholipids. Phylo...
Source: Antonie van Leeuwenhoek - May 1, 2024 Category: Microbiology Authors: Ya-Fei Zhang Yun-Lin Peng Yong-Hui Xiao Bing Yu Ming-Yue Cao Zhi-Ling Zhang Le-Qun Huang Yi Li Source Type: research
Jeotgalibacillus haloalkalitolerans sp. nov., a novel alkalitolerant and halotolerant bacterium, isolated from the confluence of the Fenhe River and the Yellow River
Antonie Van Leeuwenhoek. 2024 May 1;117(1):74. doi: 10.1007/s10482-024-01968-8.ABSTRACTA Gram-stain positive, aerobic, alkalitolerant and halotolerant bacterium, designated HH7-29 T, was isolated from the confluence of the Fenhe River and the Yellow River in Shanxi Province, PR China. Growth occurred at pH 6.0-12.0 (optimum, pH 8.0-8.5) and 15-40℃ (optimum, 32℃) with 0.5-24% NaCl (optimum, 2-9%). The predominant fatty acids (> 10.0%) were iso-C15:0 and anteiso-C15:0. The major menaquinones were MK-7 and MK-8. The polar lipids were phosphatidylglycerol, diphosphatidylglycerol and two unidentified phospholipids. Phylo...
Source: Antonie van Leeuwenhoek - May 1, 2024 Category: Microbiology Authors: Ya-Fei Zhang Yun-Lin Peng Yong-Hui Xiao Bing Yu Ming-Yue Cao Zhi-Ling Zhang Le-Qun Huang Yi Li Source Type: research
Genetic polymorphisms and major bleeding risk during vitamin K antagonists treatment: The BLEEDS case ‐cohort
ConclusionsCYP4F2 polymorphism was associated with major bleeding, especially in combination withVKORC1 genetic variants. These variants could be considered to further personalize anticoagulant treatment. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - May 1, 2024 Category: Drugs & Pharmacology Authors: Eleonora Camilleri,
Mira Ghobreyal,
Mettine H. A. Bos,
Pieter H. Reitsma,
Felix J. M. Van Der Meer,
Jesse J. Swen,
Suzanne C. Cannegieter,
Nienke van Rein Tags: RESEARCH ARTICLE Source Type: research
Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline
Hamostaseologie. 2024 Apr;44(2):97-110. doi: 10.1055/a-2178-6574. Epub 2024 Apr 30.ABSTRACTDeep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity veins. Since the symptoms of DVT are non-specific, a prompt and standardised diagnostic work-up is essential to minimise the risk of PE in the acute phase and to prevent thrombosis progression, post-thrombotic syndrome and VTE recurrence in the long-term. Only recently, the AWMF S2k guidelines on Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism have been rev...
Source: Hamostaseologie - April 30, 2024 Category: Hematology Authors: Birgit Linnemann Jan Beyer-Westendorf Christine Espinola-Klein Katja S M ühlberg Oliver J M üller Robert Klamroth Source Type: research
Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline
Hamostaseologie. 2024 Apr;44(2):97-110. doi: 10.1055/a-2178-6574. Epub 2024 Apr 30.ABSTRACTDeep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity veins. Since the symptoms of DVT are non-specific, a prompt and standardised diagnostic work-up is essential to minimise the risk of PE in the acute phase and to prevent thrombosis progression, post-thrombotic syndrome and VTE recurrence in the long-term. Only recently, the AWMF S2k guidelines on Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism have been rev...
Source: Hamostaseologie - April 30, 2024 Category: Hematology Authors: Birgit Linnemann Jan Beyer-Westendorf Christine Espinola-Klein Katja S M ühlberg Oliver J M üller Robert Klamroth Source Type: research
Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline
Hamostaseologie. 2024 Apr;44(2):97-110. doi: 10.1055/a-2178-6574. Epub 2024 Apr 30.ABSTRACTDeep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity veins. Since the symptoms of DVT are non-specific, a prompt and standardised diagnostic work-up is essential to minimise the risk of PE in the acute phase and to prevent thrombosis progression, post-thrombotic syndrome and VTE recurrence in the long-term. Only recently, the AWMF S2k guidelines on Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism have been rev...
Source: Hamostaseologie - April 30, 2024 Category: Hematology Authors: Birgit Linnemann Jan Beyer-Westendorf Christine Espinola-Klein Katja S M ühlberg Oliver J M üller Robert Klamroth Source Type: research
Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline
Hamostaseologie. 2024 Apr;44(2):97-110. doi: 10.1055/a-2178-6574. Epub 2024 Apr 30.ABSTRACTDeep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity veins. Since the symptoms of DVT are non-specific, a prompt and standardised diagnostic work-up is essential to minimise the risk of PE in the acute phase and to prevent thrombosis progression, post-thrombotic syndrome and VTE recurrence in the long-term. Only recently, the AWMF S2k guidelines on Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism have been rev...
Source: Hamostaseologie - April 30, 2024 Category: Hematology Authors: Birgit Linnemann Jan Beyer-Westendorf Christine Espinola-Klein Katja S M ühlberg Oliver J M üller Robert Klamroth Source Type: research
Management of Deep Vein Thrombosis: An Update Based on the Revised AWMF S2k Guideline
Hamostaseologie. 2024 Apr;44(2):97-110. doi: 10.1055/a-2178-6574. Epub 2024 Apr 30.ABSTRACTDeep vein thrombosis (DVT) and pulmonary embolism (PE) are the most common manifestations of venous thromboembolism (VTE). Most DVTs affect the lower-extremity veins. Since the symptoms of DVT are non-specific, a prompt and standardised diagnostic work-up is essential to minimise the risk of PE in the acute phase and to prevent thrombosis progression, post-thrombotic syndrome and VTE recurrence in the long-term. Only recently, the AWMF S2k guidelines on Diagnostics and Therapy of Venous Thrombosis and Pulmonary Embolism have been rev...
Source: Hamostaseologie - April 30, 2024 Category: Hematology Authors: Birgit Linnemann Jan Beyer-Westendorf Christine Espinola-Klein Katja S M ühlberg Oliver J M üller Robert Klamroth Source Type: research
Clinical care pathway and management of major bleeding associated with non-vitamin k antagonist oral anticoagulants: a modified delphi consensus from saudi arabia and uae
Conclusion: The present Delphi consensus provides evidence-based recommendations and protocols for the management of NOAC-associated bleeding in the region. Patients with major NOAC-induced bleeding should be referred to a well-equipped ED with standardized management protocols. A multidisciplinary approach is recommended for establishing the association between NOAC use and major bleeding. Treating physicians should have prompt access to specific reversal agents to optimize patient outcomes. Real-world evidence and national guidelines are needed to aid all stakeholders involved in NOAC-induced bleeding management. (Source...
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: Abdulrahman Al Raizah, Fakhr Alayoubi, Galal Hassan Abdelnaby, Hazzaa Alzahrani, Majid Farraj Bakheet, Mohammed A Alskaini, Rasha Buhumaid, Sameer Al Awadhi, Sara Nooruddin Kazim, Thiagarajan Jaiganesh, Zohair Al Asiri Source Type: research
