Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Management and outcome of patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era - analysis of the European LeukemiaNet Blast Phase Registry
Leukemia. 2024 Mar 28. doi: 10.1038/s41375-024-02204-y. Online ahead of print.ABSTRACTBlast phase (BP) of chronic myeloid leukemia (CML) still represents an unmet clinical need with a dismal prognosis. Due to the rarity of the condition and the heterogeneity of the biology and clinical presentation, prospective trials and concise treatment recommendations are lacking. Here we present the analysis of the European LeukemiaNet Blast Phase Registry, an international collection of the clinical presentation, treatment and outcome of blast phases which had been diagnosed in CML patients after 2015. Data reveal the expected hetero...
Source: Hamostaseologie - March 29, 2024 Category: Hematology Authors: Annamaria Brioli Elza Lomaia Christian Fabisch Tomasz Sacha Hana Klamova Elena Morozova Aleksandra Golos Philipp Ernst Ulla Olsson-Stromberg Daniela Zackova Franck E Nicolini Han Bao Fausto Castagnetti Elzbieta Patkowska Jiri Mayer Klaus Hirschb ühl Hele Source Type: research

Integration of Extracorporeal Membrane Oxygenation into the Management of High-Risk Pulmonary Embolism: An Overview of Current Evidence
Hamostaseologie. 2024 Mar 26. doi: 10.1055/a-2215-9003. Online ahead of print.ABSTRACTHigh-risk pulmonary embolism (PE) refers to a large embolic burden causing right ventricular failure and hemodynamic instability. It accounts for approximately 5% of all cases of PE but contributes significantly to overall PE mortality. Systemic thrombolysis is the first-line revascularization therapy in high-risk PE. Surgical embolectomy or catheter-directed therapy is recommended in patients with an absolute contraindication to systemic thrombolysis. Extracorporeal membrane oxygenation (ECMO) provides respiratory and hemodynamic support...
Source: Hamostaseologie - March 26, 2024 Category: Hematology Authors: Romain Chopard Raquel Morillo Nicolas Meneveau David Jim énez Source Type: research