Non-valvular atrial fibrillation in patients on peritoneal dialysis, prevalence, treatment and professionals involved
The objective of our study was to know the prevalence, treatment and professionals involved in the management of atrial fibrillation in peritoneal dialysis patients. For this purpose, we performed a descriptive analysis through a survey sent to different peritoneal dialysis units in Spain. A total of 1,403 patients on peritoneal dialysis were included in the study, of whom 186 (13.2%) had non-valvular atrial fibrillation. In addition, the assessment of the scores of thromboembolic and bleeding risks for the indication of oral anticoagulation was mainly carried out by the cardiologist (60% of the units), as well as its pres...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 12, 2024 Category: Urology & Nephrology Authors: Elisa Perez-Bernat M ª Angeles Viñas Manel Vera Miguel Gonz ález-Rico Marco Montomoli Elena Astudillo-Cort és Juan Carlos Quevedo-Reina Isabel Garc ía-Méndez Adoraci ón Martinez-Losa Ines Rama-Arias Mar ía Maldonado-Martín M ª Antonia Munar Agus Source Type: research
Validating nutrient selection for product-group-specific nutrient indices for use as functional units in life cycle assessment of foods
Br J Nutr. 2024 Apr 12:1-23. doi: 10.1017/S0007114524000709. Online ahead of print.ABSTRACTThe ability to provide adequate nutrition is considered a key factor in evaluating the sustainability of foods and diets. Nutrient indices are used as functional units (FUs) in life cycle assessment of foods to include nutritional performance in the environmental assessment of a product. Several general and food group-specific nutrient indices exist but many lack validation, particularly when used as FU. In addition, the nutrient selection strategies and reference units for nutrient intake can vary considerably among studies. To vali...
Source: The British Journal of Nutrition - April 12, 2024 Category: Nutrition Authors: Anna K årlund Venla Kytt ä Tiina Pellinen Hanna L Tuomisto Anne-Maria Pajari Marjukka Kolehmainen Merja Saarinen Source Type: research
Validating nutrient selection for product-group-specific nutrient indices for use as functional units in life cycle assessment of foods
Br J Nutr. 2024 Apr 12:1-23. doi: 10.1017/S0007114524000709. Online ahead of print.ABSTRACTThe ability to provide adequate nutrition is considered a key factor in evaluating the sustainability of foods and diets. Nutrient indices are used as functional units (FUs) in life cycle assessment of foods to include nutritional performance in the environmental assessment of a product. Several general and food group-specific nutrient indices exist but many lack validation, particularly when used as FU. In addition, the nutrient selection strategies and reference units for nutrient intake can vary considerably among studies. To vali...
Source: The British Journal of Nutrition - April 12, 2024 Category: Nutrition Authors: Anna K årlund Venla Kytt ä Tiina Pellinen Hanna L Tuomisto Anne-Maria Pajari Marjukka Kolehmainen Merja Saarinen Source Type: research
Non-valvular atrial fibrillation in patients on peritoneal dialysis, prevalence, treatment and professionals involved
The objective of our study was to know the prevalence, treatment and professionals involved in the management of atrial fibrillation in peritoneal dialysis patients. For this purpose, we performed a descriptive analysis through a survey sent to different peritoneal dialysis units in Spain. A total of 1,403 patients on peritoneal dialysis were included in the study, of whom 186 (13.2%) had non-valvular atrial fibrillation. In addition, the assessment of the scores of thromboembolic and bleeding risks for the indication of oral anticoagulation was mainly carried out by the cardiologist (60% of the units), as well as its pres...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - April 12, 2024 Category: Urology & Nephrology Authors: Elisa Perez-Bernat M ª Angeles Viñas Manel Vera Miguel Gonz ález-Rico Marco Montomoli Elena Astudillo-Cort és Juan Carlos Quevedo-Reina Isabel Garc ía-Méndez Adoraci ón Martinez-Losa Ines Rama-Arias Mar ía Maldonado-Martín M ª Antonia Munar Agus Source Type: research
< em > Micromonospora cathayae < /em > sp. nov., isolated from the rhizosphere soil of < em > Cathaya argyrophylla < /em >
Int J Syst Evol Microbiol. 2024 Apr;74(4). doi: 10.1099/ijsem.0.006332.ABSTRACTA novel actinobacterium, strain HUAS 3T, was isolated from the rhizosphere soil of Cathaya argyrophylla collected in Hunan Province, PR China. Strain HUAS 3T contained meso-diaminopimelic acid in the cell-wall peptidoglycan. The dominant menaquinones were MK-9(H4), MK-9(H6), MK-10(H2) and MK-9(H4). The polar lipids consisted of diphosphatidylglycerol, phospholipids, phosphatidylethanolamine, phosphatidylglycerol, phosphotidylinositol and phosphatidylinositol mannosides. The main cellular fatty acids (>5.0 %) were C17 : 1 ω8c, iso-C16 : 0, C1...
Source: International Journal of Systematic and Evolutionary Microbiology - April 11, 2024 Category: Microbiology Authors: Pei-Lan Long Li Fu Yan Xiao Jian Gao Source Type: research
< em > Micromonospora cathayae < /em > sp. nov., isolated from the rhizosphere soil of < em > Cathaya argyrophylla < /em >
Int J Syst Evol Microbiol. 2024 Apr;74(4). doi: 10.1099/ijsem.0.006332.ABSTRACTA novel actinobacterium, strain HUAS 3T, was isolated from the rhizosphere soil of Cathaya argyrophylla collected in Hunan Province, PR China. Strain HUAS 3T contained meso-diaminopimelic acid in the cell-wall peptidoglycan. The dominant menaquinones were MK-9(H4), MK-9(H6), MK-10(H2) and MK-9(H4). The polar lipids consisted of diphosphatidylglycerol, phospholipids, phosphatidylethanolamine, phosphatidylglycerol, phosphotidylinositol and phosphatidylinositol mannosides. The main cellular fatty acids (>5.0 %) were C17 : 1 ω8c, iso-C16 : 0, C1...
Source: International Journal of Systematic and Evolutionary Microbiology - April 11, 2024 Category: Microbiology Authors: Pei-Lan Long Li Fu Yan Xiao Jian Gao Source Type: research
Small bowel intramural hematoma caused by warfarin: case report and literature review
CONCLUSION: Our analysis highlights that hematoma in the small intestinal wall caused by warfarin overdose often presents as sudden and intense abdominal pain, laboratory tests suggest reduced coagulation capacity, and imaging often shows thickening of the intestinal wall. Intravenous vitamin K and plasma supplementation are effective non-surgical strategies. Nevertheless, in instances of severe obstruction and unresponsive hemostasis, surgical resection of necrotic intestinal segments may be necessary. In the cases we reported, we avoided surgery by closely monitoring the coagulation function. Therefore, we suggest that i...
Source: Scandinavian Journal of Gastroenterology - April 10, 2024 Category: Gastroenterology Authors: Zihao Wang Tianxiang Jiang Mingchun Mu Chaoyong Shen Zhaolun Cai Haining Chen Bo Zhang Source Type: research
Cancers, Vol. 16, Pages 1453: Emerging and Clinically Accepted Biomarkers for Hepatocellular Carcinoma
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R. Matthew Walsh
Charles Miller
Koji Hashimoto
Andrea Schlegel
David Choon Hyuck Kwon
Federico Aucejo
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death and the sixth most diagnosed malignancy worldwide. Serum alpha-fetoprotein (AFP) is the traditional, ubiquitous biomarker for HCC. However, there has been an increasing call for the use of multiple biomarkers to optimize care for these patients. AFP, AFP-L3, and prothrombin induced by vitamin K absence II (DCP) have described clinical utility for HCC, but unfortunately, they also have well established and significant limitat...
Source: Cancers - April 10, 2024 Category: Cancer & Oncology Authors: Sami Fares Chase J. Wehrle Hanna Hong Keyue Sun Chunbao Jiao Mingyi Zhang Abby Gross Erlind Allkushi Melis Uysal Suneel Kamath Wen Wee Ma Jamak Modaresi Esfeh Maureen Whitsett Linganna Mazhar Khalil Alejandro Pita Jaekeun Kim R. Matthew Walsh Charles Mill Tags: Review Source Type: research
Mechanisms of Cardiovascular Calcification and Experimental Models: Impact of Vitamin K Antagonists
J Clin Med. 2024 Feb 29;13(5):1405. doi: 10.3390/jcm13051405.ABSTRACTCardiovascular calcification is a multifactorial and complex process involving an array of molecular mechanisms eventually leading to calcium deposition within the arterial walls. This process increases arterial stiffness, decreases elasticity, influences shear stress events and is related to an increased risk of morbidity and mortality associated with cardiovascular disease. In numerous in vivo and in vitro models, warfarin therapy has been shown to cause vascular calcification in the arterial wall. However, the exact mechanisms of calcification formatio...
Source: Atherosclerosis - April 9, 2024 Category: Cardiology Authors: Chiara Siracusa Annarita Carino Nicole Carabetta Marzia Manica Jolanda Sabatino Eleonora Cianflone Isabella Leo Antonio Strangio Daniele Torella Salvatore De Rosa Source Type: research
Mechanisms of Cardiovascular Calcification and Experimental Models: Impact of Vitamin K Antagonists
J Clin Med. 2024 Feb 29;13(5):1405. doi: 10.3390/jcm13051405.ABSTRACTCardiovascular calcification is a multifactorial and complex process involving an array of molecular mechanisms eventually leading to calcium deposition within the arterial walls. This process increases arterial stiffness, decreases elasticity, influences shear stress events and is related to an increased risk of morbidity and mortality associated with cardiovascular disease. In numerous in vivo and in vitro models, warfarin therapy has been shown to cause vascular calcification in the arterial wall. However, the exact mechanisms of calcification formatio...
Source: Atherosclerosis - April 9, 2024 Category: Cardiology Authors: Chiara Siracusa Annarita Carino Nicole Carabetta Marzia Manica Jolanda Sabatino Eleonora Cianflone Isabella Leo Antonio Strangio Daniele Torella Salvatore De Rosa Source Type: research
Role of the Clinical Features and MRI Parameters on Ki-67 Expression in Hepatocellular Carcinoma Patients: Development of a Predictive Nomogram
ConclusionA non-invasive preoperative prediction method, which incorporates MRI variables and clinical features was developed, and showed effectiveness in evaluating Ki-67 expression in HCC patients. (Source: Journal of Gastrointestinal Cancer)
Source: Journal of Gastrointestinal Cancer - April 9, 2024 Category: Cancer & Oncology Source Type: research
Evaluation of modified fixed dose four-factor prothrombin complex concentrate for warfarin reversal
AbstractNon-activated four-factor prothrombin complex concentrate (4 F-PCC) has emerged as the preferred reversal strategy for patients on warfarin with life-threatening bleeding. Current dosing recommendations for 4 F-PCC require pre-treatment international normalized ratio (INR) and bodyweight values, resulting in ordering and administration delays. Studies have shown that alternative dosing regimens are safe and efficacious. This retrospective, single-center, pre- and post-protocol analysis was conducted to assess the efficacy of a pharmacist driven modified fixed-dose 4 F-PCC regimen versus package insert weight- a...
Source: Journal of Thrombosis and Thrombolysis - April 6, 2024 Category: Hematology Source Type: research
The effect of administering preprocedural VITamin K on the international normalized ratio in patients anticoagulated with ACEnocoumarol (VITKACE-study)
CONCLUSIONS: Using oral vitamin K while patients continue acenocoumarol intake is an effective way to adequately lower INR before an invasive procedure. Low amount of bleeding complications and absence of thromboembolic complications suggest that this is a safe strategy. The INR-values returned gradually to therapeutic range after the procedure, probably contributing to the observed low bleeding rate.PMID:38580096 | DOI:10.1016/j.jtha.2024.03.016 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 5, 2024 Category: Hematology Authors: Stella Bijkerk Harm J Lourens Wout G N Mares Corine A van Kampen Maurits J van der Veen Henk J Adriaansen Erik D Ponfoort Barbara Festen G Wouter Westendorp J örgen M P Rovers Gerie M C Groot Hans-Peter R Bootsma Linde M Amelung Sander Bins Gerjo Velders Source Type: research
The effect of administering preprocedural VITamin K on the international normalized ratio in patients anticoagulated with ACEnocoumarol (VITKACE-study)
CONCLUSIONS: Using oral vitamin K while patients continue acenocoumarol intake is an effective way to adequately lower INR before an invasive procedure. Low amount of bleeding complications and absence of thromboembolic complications suggest that this is a safe strategy. The INR-values returned gradually to therapeutic range after the procedure, probably contributing to the observed low bleeding rate.PMID:38580096 | DOI:10.1016/j.jtha.2024.03.016 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 5, 2024 Category: Hematology Authors: Stella Bijkerk Harm J Lourens Wout G N Mares Corine A van Kampen Maurits J van der Veen Henk J Adriaansen Erik D Ponfoort Barbara Festen G Wouter Westendorp J örgen M P Rovers Gerie M C Groot Hans-Peter R Bootsma Linde M Amelung Sander Bins Gerjo Velders Source Type: research
