Therapy outcome related to adalimumab trough levels in pediatric patients with inflammatory bowel disease
Scand J Gastroenterol. 2021 Sep 21:1-6. doi: 10.1080/00365521.2021.1977843. Online ahead of print.ABSTRACTOBJECTIVES: We evaluated the relationship between serum concentration and efficacy of adalimumab (ADA), an anti-tumor necrosis factor-alpha agent, in pediatric patients with inflammatory bowel disease (PIBD).MATERIALS AND METHODS: This retrospective cross-sectional study traced 75 patients with PIBD (Crohn's disease, n = 57) treated with ADA at two tertiary centers in Finland in 2012-2018. Drug levels and drug antibody titers were chart-reviewed, and the treatment continuation rate of ADA therapy was evaluated. We also...
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Johanna Lehtom äki Anne Nikkonen Laura Merras-Salmio Pauliina Hiltunen Kaija-Leena Kolho Source Type: research

Predictors and timing for the development of symptomatic gastroesophageal reflux disease after successful < em > Helicobactor pylori < /em > eradication therapy
CONCLUSIONS: The rate of development of symptomatic GERD after successful H. pylori eradication is low over long-term follow-up and is easily controlled by vonoprazan therapy. However, patients with smoking habits, functional dyspepsia, hiatal hernia, or severe gastric atrophy should be followed carefully after eradication.PMID:34547219 | DOI:10.1080/00365521.2021.1975310 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Satoshi Shinozaki Hiroyuki Osawa Yoshikazu Hayashi Yoshimasa Miura Tomonori Yano Alan Kawarai Lefor Hironori Yamamoto Source Type: research

Therapy outcome related to adalimumab trough levels in pediatric patients with inflammatory bowel disease
Scand J Gastroenterol. 2021 Sep 21:1-6. doi: 10.1080/00365521.2021.1977843. Online ahead of print.ABSTRACTOBJECTIVES: We evaluated the relationship between serum concentration and efficacy of adalimumab (ADA), an anti-tumor necrosis factor-alpha agent, in pediatric patients with inflammatory bowel disease (PIBD).MATERIALS AND METHODS: This retrospective cross-sectional study traced 75 patients with PIBD (Crohn's disease, n = 57) treated with ADA at two tertiary centers in Finland in 2012-2018. Drug levels and drug antibody titers were chart-reviewed, and the treatment continuation rate of ADA therapy was evaluated. We also...
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Johanna Lehtom äki Anne Nikkonen Laura Merras-Salmio Pauliina Hiltunen Kaija-Leena Kolho Source Type: research

Predictors and timing for the development of symptomatic gastroesophageal reflux disease after successful < em > Helicobactor pylori < /em > eradication therapy
CONCLUSIONS: The rate of development of symptomatic GERD after successful H. pylori eradication is low over long-term follow-up and is easily controlled by vonoprazan therapy. However, patients with smoking habits, functional dyspepsia, hiatal hernia, or severe gastric atrophy should be followed carefully after eradication.PMID:34547219 | DOI:10.1080/00365521.2021.1975310 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Satoshi Shinozaki Hiroyuki Osawa Yoshikazu Hayashi Yoshimasa Miura Tomonori Yano Alan Kawarai Lefor Hironori Yamamoto Source Type: research

Therapy outcome related to adalimumab trough levels in pediatric patients with inflammatory bowel disease
Scand J Gastroenterol. 2021 Sep 21:1-6. doi: 10.1080/00365521.2021.1977843. Online ahead of print.ABSTRACTOBJECTIVES: We evaluated the relationship between serum concentration and efficacy of adalimumab (ADA), an anti-tumor necrosis factor-alpha agent, in pediatric patients with inflammatory bowel disease (PIBD).MATERIALS AND METHODS: This retrospective cross-sectional study traced 75 patients with PIBD (Crohn's disease, n = 57) treated with ADA at two tertiary centers in Finland in 2012-2018. Drug levels and drug antibody titers were chart-reviewed, and the treatment continuation rate of ADA therapy was evaluated. We also...
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Johanna Lehtom äki Anne Nikkonen Laura Merras-Salmio Pauliina Hiltunen Kaija-Leena Kolho Source Type: research

Predictors and timing for the development of symptomatic gastroesophageal reflux disease after successful < em > Helicobactor pylori < /em > eradication therapy
CONCLUSIONS: The rate of development of symptomatic GERD after successful H. pylori eradication is low over long-term follow-up and is easily controlled by vonoprazan therapy. However, patients with smoking habits, functional dyspepsia, hiatal hernia, or severe gastric atrophy should be followed carefully after eradication.PMID:34547219 | DOI:10.1080/00365521.2021.1975310 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Satoshi Shinozaki Hiroyuki Osawa Yoshikazu Hayashi Yoshimasa Miura Tomonori Yano Alan Kawarai Lefor Hironori Yamamoto Source Type: research

Therapy outcome related to adalimumab trough levels in pediatric patients with inflammatory bowel disease
Scand J Gastroenterol. 2021 Sep 21:1-6. doi: 10.1080/00365521.2021.1977843. Online ahead of print.ABSTRACTOBJECTIVES: We evaluated the relationship between serum concentration and efficacy of adalimumab (ADA), an anti-tumor necrosis factor-alpha agent, in pediatric patients with inflammatory bowel disease (PIBD).MATERIALS AND METHODS: This retrospective cross-sectional study traced 75 patients with PIBD (Crohn's disease, n = 57) treated with ADA at two tertiary centers in Finland in 2012-2018. Drug levels and drug antibody titers were chart-reviewed, and the treatment continuation rate of ADA therapy was evaluated. We also...
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Johanna Lehtom äki Anne Nikkonen Laura Merras-Salmio Pauliina Hiltunen Kaija-Leena Kolho Source Type: research

Predictors and timing for the development of symptomatic gastroesophageal reflux disease after successful < em > Helicobactor pylori < /em > eradication therapy
CONCLUSIONS: The rate of development of symptomatic GERD after successful H. pylori eradication is low over long-term follow-up and is easily controlled by vonoprazan therapy. However, patients with smoking habits, functional dyspepsia, hiatal hernia, or severe gastric atrophy should be followed carefully after eradication.PMID:34547219 | DOI:10.1080/00365521.2021.1975310 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 21, 2021 Category: Gastroenterology Authors: Satoshi Shinozaki Hiroyuki Osawa Yoshikazu Hayashi Yoshimasa Miura Tomonori Yano Alan Kawarai Lefor Hironori Yamamoto Source Type: research

Excellent outcome following emergency deceased donor ABO-incompatible liver transplantation using rituximab and antigen specific immunoadsorption
CONCLUSION: Patient and graft survival after emergency ABOi DDLT using rituximab and immunoadorption was equal to ABOid/DDLT. ABOi DD LT was a successful approach to expand the donor pool for patients in urgent need for a liver graft.PMID:34541993 | DOI:10.1080/00365521.2021.1976269 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 20, 2021 Category: Gastroenterology Authors: Ulrika Skogsberg Dahlgren Gustaf Herlenius Bengt Gustafsson Johan M ölne Lennart Rydberg Andreas Socratous William Bennet Source Type: research

Comparison of assessment tools in acute upper gastrointestinal bleeding: which one for which decision
CONCLUSIONS: At admission, GBS and ABC scores identify low-risk patients suitable for outpatient management, while PNED and ABC scores identify high-risk patients. During hospitalization, the PNED score should be used to re-assess the mortality risk if a modification of clinical status occurs.PMID:34534036 | DOI:10.1080/00365521.2021.1976268 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 17, 2021 Category: Gastroenterology Authors: Riccardo Marmo Marco Soncini Cristina Bucci Angelo Zullo Source Type: research

Women require routine opioids to prevent painful colonoscopies: a randomised controlled trial
Scand J Gastroenterol. 2021 Sep 17:1-10. doi: 10.1080/00365521.2021.1969683. Online ahead of print.ABSTRACTBACKGROUND: Women are at high risk for painful colonoscopy. Pain, but also sedation, are barriers to colorectal cancer (CRC) screening participation. In a randomised controlled trial, we compared on-demand with pre-colonoscopy opioid administration to control pain in women at CRC screening age.METHODS: Women, aged 55-79 years, attending colonoscopy at two Norwegian endoscopy units were randomised 1:1:1 to (1) fentanyl on-demand, (2) fentanyl prior to colonoscopy, or (3) alfentanil on-demand. The primary endpoint was p...
Source: Scandinavian Journal of Gastroenterology - September 17, 2021 Category: Gastroenterology Authors: Anna Lisa Schult Edoardo Botteri Geir Hoff Øyvind Holme Michael Bretthauer Kristin Ranheim Randel Elisabeth Haagensen Gulichsen Badboni El-Safadi Ishita Barua Carl Munck Linn Ros én Nilsen Hege Marie Svendsen Thomas de Lange Source Type: research

Measuring the impact of gastrointestinal inconvenience and symptoms on perceived health in the general population - validation of the Short Health Scale for gastrointestinal symptoms (SHS-GI)
CONCLUSIONS: SHS-GI demonstrated appropriate psychometric properties in a sample of the normal population. We suggest that SHS-GI is a valid simple questionnaire suitable for measuring the impact of GI symptoms and inconvenience on quality of life in both general and patient populations.PMID:34521305 | DOI:10.1080/00365521.2021.1974087 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Susanna Walter Michael P Jones Jenny Sj ödahl Henrik Stjernman Henrik Hjortswang Anna Andreasson Source Type: research

Low-volume regimen without additional liquids or adjunctive agents versus standard bowel preparation in non-constipated patients: a propensity score matching analysis
CONCLUSION: For non-constipated patients, LSD is not inferior to HSD in cleansing efficiency, while more willing to repeat the same BP.PMID:34521311 | DOI:10.1080/00365521.2021.1977842 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Xiang Li Lei Diao Weiping Zhang Renyu Fan Chen Shi Yufang Cui Jianglong Hong Source Type: research

Small sessile serrated polyps might not be at a higher risk for future advanced neoplasia than low-risk adenomas or polyp-free groups
This study aimed to evaluate the risk of advanced neoplasia following low-risk SSPs compared with that following LRAs and polyp-free groups.MATERIALS AND METHODS: From September 2013 to August 2017, asymptomatic Koreans aged 50-75 years who underwent surveillance colonoscopy post-baseline colonoscopy were enrolled. The 1314 participants who met the study design criteria were stratified into three groups according to the presence of LRAs or low-risk SSPs. The rate of advanced neoplasia was then compared between groups by surveillance colonoscopy.RESULTS: A total of 1314 participants were classified according to baseline col...
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Eun Hyo Jin Ji Yeon Seo Jung Ho Bae Jooyoung Lee Ji Min Choi Yoo Min Han Joo Hyun Lim Source Type: research

Percutaneous endoscopic gastrostomy: a dislodgement complication due to a moving hiatal hernia
Conclusions: This case challenges the use of PEG as an only means for gastric fixation for hiatal hernia.PMID:34524046 | DOI:10.1080/00365521.2021.1974085 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Miia L Lehtinen Ilkka Ilonen Juha Kauppi Jari R äsänen Source Type: research

Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?
Scand J Gastroenterol. 2021 Sep 15:1-6. doi: 10.1080/00365521.2021.1974932. Online ahead of print.ABSTRACTBACKGROUND: Poorly differentiated Clusters (PDCs) of tumor cells composed of more than five elements have been recently described in gastrointestinal cancers and correlate with a worse prognosis. Our study aims to investigate PDC occurrence in a series of patients with gastric cancer and correlate it with lymph node status and clinical outcome.MATERIAL AND METHODS: 50 patients were included in the study; PDCs count was graduated as G1, G2, and G3 according to Ueno classification (PDCs count at 20×
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: L Sorrentino N De Ruvo F Serra M Salati A A Ricciardolo L R Bonetti R Gelmini Source Type: research

Measuring the impact of gastrointestinal inconvenience and symptoms on perceived health in the general population - validation of the Short Health Scale for gastrointestinal symptoms (SHS-GI)
CONCLUSIONS: SHS-GI demonstrated appropriate psychometric properties in a sample of the normal population. We suggest that SHS-GI is a valid simple questionnaire suitable for measuring the impact of GI symptoms and inconvenience on quality of life in both general and patient populations.PMID:34521305 | DOI:10.1080/00365521.2021.1974087 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Susanna Walter Michael P Jones Jenny Sj ödahl Henrik Stjernman Henrik Hjortswang Anna Andreasson Source Type: research

Low-volume regimen without additional liquids or adjunctive agents versus standard bowel preparation in non-constipated patients: a propensity score matching analysis
CONCLUSION: For non-constipated patients, LSD is not inferior to HSD in cleansing efficiency, while more willing to repeat the same BP.PMID:34521311 | DOI:10.1080/00365521.2021.1977842 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Xiang Li Lei Diao Weiping Zhang Renyu Fan Chen Shi Yufang Cui Jianglong Hong Source Type: research

Small sessile serrated polyps might not be at a higher risk for future advanced neoplasia than low-risk adenomas or polyp-free groups
This study aimed to evaluate the risk of advanced neoplasia following low-risk SSPs compared with that following LRAs and polyp-free groups.MATERIALS AND METHODS: From September 2013 to August 2017, asymptomatic Koreans aged 50-75 years who underwent surveillance colonoscopy post-baseline colonoscopy were enrolled. The 1314 participants who met the study design criteria were stratified into three groups according to the presence of LRAs or low-risk SSPs. The rate of advanced neoplasia was then compared between groups by surveillance colonoscopy.RESULTS: A total of 1314 participants were classified according to baseline col...
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Eun Hyo Jin Ji Yeon Seo Jung Ho Bae Jooyoung Lee Ji Min Choi Yoo Min Han Joo Hyun Lim Source Type: research

Percutaneous endoscopic gastrostomy: a dislodgement complication due to a moving hiatal hernia
Conclusions: This case challenges the use of PEG as an only means for gastric fixation for hiatal hernia.PMID:34524046 | DOI:10.1080/00365521.2021.1974085 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Miia L Lehtinen Ilkka Ilonen Juha Kauppi Jari R äsänen Source Type: research

Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?
Scand J Gastroenterol. 2021 Sep 15:1-6. doi: 10.1080/00365521.2021.1974932. Online ahead of print.ABSTRACTBACKGROUND: Poorly differentiated Clusters (PDCs) of tumor cells composed of more than five elements have been recently described in gastrointestinal cancers and correlate with a worse prognosis. Our study aims to investigate PDC occurrence in a series of patients with gastric cancer and correlate it with lymph node status and clinical outcome.MATERIAL AND METHODS: 50 patients were included in the study; PDCs count was graduated as G1, G2, and G3 according to Ueno classification (PDCs count at 20×
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: L Sorrentino N De Ruvo F Serra M Salati A A Ricciardolo L R Bonetti R Gelmini Source Type: research

Measuring the impact of gastrointestinal inconvenience and symptoms on perceived health in the general population - validation of the Short Health Scale for gastrointestinal symptoms (SHS-GI)
CONCLUSIONS: SHS-GI demonstrated appropriate psychometric properties in a sample of the normal population. We suggest that SHS-GI is a valid simple questionnaire suitable for measuring the impact of GI symptoms and inconvenience on quality of life in both general and patient populations.PMID:34521305 | DOI:10.1080/00365521.2021.1974087 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Susanna Walter Michael P Jones Jenny Sj ödahl Henrik Stjernman Henrik Hjortswang Anna Andreasson Source Type: research

Low-volume regimen without additional liquids or adjunctive agents versus standard bowel preparation in non-constipated patients: a propensity score matching analysis
CONCLUSION: For non-constipated patients, LSD is not inferior to HSD in cleansing efficiency, while more willing to repeat the same BP.PMID:34521311 | DOI:10.1080/00365521.2021.1977842 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Xiang Li Lei Diao Weiping Zhang Renyu Fan Chen Shi Yufang Cui Jianglong Hong Source Type: research

Small sessile serrated polyps might not be at a higher risk for future advanced neoplasia than low-risk adenomas or polyp-free groups
This study aimed to evaluate the risk of advanced neoplasia following low-risk SSPs compared with that following LRAs and polyp-free groups.MATERIALS AND METHODS: From September 2013 to August 2017, asymptomatic Koreans aged 50-75 years who underwent surveillance colonoscopy post-baseline colonoscopy were enrolled. The 1314 participants who met the study design criteria were stratified into three groups according to the presence of LRAs or low-risk SSPs. The rate of advanced neoplasia was then compared between groups by surveillance colonoscopy.RESULTS: A total of 1314 participants were classified according to baseline col...
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Eun Hyo Jin Ji Yeon Seo Jung Ho Bae Jooyoung Lee Ji Min Choi Yoo Min Han Joo Hyun Lim Source Type: research

Percutaneous endoscopic gastrostomy: a dislodgement complication due to a moving hiatal hernia
Conclusions: This case challenges the use of PEG as an only means for gastric fixation for hiatal hernia.PMID:34524046 | DOI:10.1080/00365521.2021.1974085 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Miia L Lehtinen Ilkka Ilonen Juha Kauppi Jari R äsänen Source Type: research

Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?
Scand J Gastroenterol. 2021 Sep 15:1-6. doi: 10.1080/00365521.2021.1974932. Online ahead of print.ABSTRACTBACKGROUND: Poorly differentiated Clusters (PDCs) of tumor cells composed of more than five elements have been recently described in gastrointestinal cancers and correlate with a worse prognosis. Our study aims to investigate PDC occurrence in a series of patients with gastric cancer and correlate it with lymph node status and clinical outcome.MATERIAL AND METHODS: 50 patients were included in the study; PDCs count was graduated as G1, G2, and G3 according to Ueno classification (PDCs count at 20×
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: L Sorrentino N De Ruvo F Serra M Salati A A Ricciardolo L R Bonetti R Gelmini Source Type: research

Measuring the impact of gastrointestinal inconvenience and symptoms on perceived health in the general population - validation of the Short Health Scale for gastrointestinal symptoms (SHS-GI)
CONCLUSIONS: SHS-GI demonstrated appropriate psychometric properties in a sample of the normal population. We suggest that SHS-GI is a valid simple questionnaire suitable for measuring the impact of GI symptoms and inconvenience on quality of life in both general and patient populations.PMID:34521305 | DOI:10.1080/00365521.2021.1974087 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Susanna Walter Michael P Jones Jenny Sj ödahl Henrik Stjernman Henrik Hjortswang Anna Andreasson Source Type: research

Low-volume regimen without additional liquids or adjunctive agents versus standard bowel preparation in non-constipated patients: a propensity score matching analysis
CONCLUSION: For non-constipated patients, LSD is not inferior to HSD in cleansing efficiency, while more willing to repeat the same BP.PMID:34521311 | DOI:10.1080/00365521.2021.1977842 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Xiang Li Lei Diao Weiping Zhang Renyu Fan Chen Shi Yufang Cui Jianglong Hong Source Type: research

Small sessile serrated polyps might not be at a higher risk for future advanced neoplasia than low-risk adenomas or polyp-free groups
This study aimed to evaluate the risk of advanced neoplasia following low-risk SSPs compared with that following LRAs and polyp-free groups.MATERIALS AND METHODS: From September 2013 to August 2017, asymptomatic Koreans aged 50-75 years who underwent surveillance colonoscopy post-baseline colonoscopy were enrolled. The 1314 participants who met the study design criteria were stratified into three groups according to the presence of LRAs or low-risk SSPs. The rate of advanced neoplasia was then compared between groups by surveillance colonoscopy.RESULTS: A total of 1314 participants were classified according to baseline col...
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Eun Hyo Jin Ji Yeon Seo Jung Ho Bae Jooyoung Lee Ji Min Choi Yoo Min Han Joo Hyun Lim Source Type: research

Percutaneous endoscopic gastrostomy: a dislodgement complication due to a moving hiatal hernia
Conclusions: This case challenges the use of PEG as an only means for gastric fixation for hiatal hernia.PMID:34524046 | DOI:10.1080/00365521.2021.1974085 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Miia L Lehtinen Ilkka Ilonen Juha Kauppi Jari R äsänen Source Type: research

Role of poorly differentiated cluster in gastric cancer: is it a new prognosis factor?
Scand J Gastroenterol. 2021 Sep 15:1-6. doi: 10.1080/00365521.2021.1974932. Online ahead of print.ABSTRACTBACKGROUND: Poorly differentiated Clusters (PDCs) of tumor cells composed of more than five elements have been recently described in gastrointestinal cancers and correlate with a worse prognosis. Our study aims to investigate PDC occurrence in a series of patients with gastric cancer and correlate it with lymph node status and clinical outcome.MATERIAL AND METHODS: 50 patients were included in the study; PDCs count was graduated as G1, G2, and G3 according to Ueno classification (PDCs count at 20×
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: L Sorrentino N De Ruvo F Serra M Salati A A Ricciardolo L R Bonetti R Gelmini Source Type: research

Measuring the impact of gastrointestinal inconvenience and symptoms on perceived health in the general population - validation of the Short Health Scale for gastrointestinal symptoms (SHS-GI)
CONCLUSIONS: SHS-GI demonstrated appropriate psychometric properties in a sample of the normal population. We suggest that SHS-GI is a valid simple questionnaire suitable for measuring the impact of GI symptoms and inconvenience on quality of life in both general and patient populations.PMID:34521305 | DOI:10.1080/00365521.2021.1974087 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Susanna Walter Michael P Jones Jenny Sj ödahl Henrik Stjernman Henrik Hjortswang Anna Andreasson Source Type: research

Low-volume regimen without additional liquids or adjunctive agents versus standard bowel preparation in non-constipated patients: a propensity score matching analysis
CONCLUSION: For non-constipated patients, LSD is not inferior to HSD in cleansing efficiency, while more willing to repeat the same BP.PMID:34521311 | DOI:10.1080/00365521.2021.1977842 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 15, 2021 Category: Gastroenterology Authors: Xiang Li Lei Diao Weiping Zhang Renyu Fan Chen Shi Yufang Cui Jianglong Hong Source Type: research

Efficacy of hemostatic powders as monotherapy or rescue therapy in gastrointestinal bleeding related to neoplastic or non-neoplastic lesions
CONCLUSIONS: HP is highly effective as monotherapy and rescue therapy in GIB. GIB related to malignancy may be the best field of application of HP, but confirmatory studies are necessary.PMID:34511014 | DOI:10.1080/00365521.2021.1974088 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 13, 2021 Category: Gastroenterology Authors: Omero Alessandro Paoluzi Carla Cardamone Antonio Aucello Benedetto Neri Enrico Grasso Mario Giannelli Laura Di Iorio Giovanni Monteleone Giovanna Del Vecchio Blanco Source Type: research

Implications of colonic and extra-colonic findings on CT colonography in FIT positive patients in the Dutch bowel cancer screening program
Scand J Gastroenterol. 2021 Sep 10:1-6. doi: 10.1080/00365521.2021.1966091. Online ahead of print.ABSTRACTOBJECTIVES: In the Dutch National colorectal cancer (CRC) screening program, patients with a positive faecal immunochemical test (FIT) are referred for a colonoscopy. In a small proportion, because of contraindications, a computed tomographic colonography (CTC) is performed to rule out advanced neoplasia. The aim of our study is to evaluate the intra- and extra-colonic yield of CTC and its clinical implications.MATERIALS AND METHODS: In this retrospective cohort study, all FIT positive patients who underwent primary (i...
Source: Scandinavian Journal of Gastroenterology - September 10, 2021 Category: Gastroenterology Authors: Marieke H A Lammertink Jelle F Huisman Marie L E Bernsen Ronald A M Niekel Henderik L van Westreenen Wouter H de Vos Tot Nederveen Cappel Bernhard W M Spanier Source Type: research

Construction of a novel predictive nomogram for difficult procedure of endoscopic submucosal dissection for colorectal neoplasms
Scand J Gastroenterol. 2021 Sep 9:1-7. doi: 10.1080/00365521.2021.1973089. Online ahead of print.ABSTRACTOBJECTIVES: To determine the predictors of difficult colorectal endoscopic submucosal dissection (ESD) and to develop a preoperative predictive model for difficult colorectal ESD procedures.METHODS: Colorectal neoplasms intended to be resected by ESD in our center between August 2013 and February 2019 were retrospectively enrolled. An ESD procedure which took more than 30 min, failed to remove the lesions en bloc or converted to surgery was defined as difficulty. Logistic regression analysis was conducted to find out th...
Source: Scandinavian Journal of Gastroenterology - September 9, 2021 Category: Gastroenterology Authors: Xiao Li Min Zhu Li Yu Yinglin Niu Ming Ji Shutian Zhang Haiyun Shi Peng Li Source Type: research

Predictors of health-related quality of life in patients with Crohn's disease receiving biological therapy
CONCLUSIONS: Abdominal pain, number of liquid stools, a new rectal fistula, arthralgia for women, clinically assessed abdominal mass for men as well as female sex, were all found to be predictors of decreased HRQoL.PMID:34493132 | DOI:10.1080/00365521.2021.1974086 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 8, 2021 Category: Gastroenterology Authors: Lasse R Lundquist Bj ørn Rasmussen Frans Boch Waldorff Sonja Wehberg Jens Kjeldsen Peter Haastrup Source Type: research

Pancreatic exocrine insufficiency in diabetes is associated with autonomic dysfunction
Scand J Gastroenterol. 2021 Sep 7:1-7. doi: 10.1080/00365521.2021.1957496. Online ahead of print.ABSTRACTOBJECTIVES: Pancreatic exocrine insufficiency (PEI) is prevalent in diabetes. Pathophysiological theories imply autoimmune destruction, lack of trophic effects of insulin or impaired neuronal stimulation, but the relationship between PEI and autonomic dysfunction is largely unknown. In a pilot study, we aimed to investigate if patients with diabetes and PEI had impaired autonomic function.METHODS: We measured faecal elastase in 59 patients with type 1 or 2 diabetes, using a cut-off-value
Source: Scandinavian Journal of Gastroenterology - September 7, 2021 Category: Gastroenterology Authors: Dag Andr é Sangnes Elisabeth Sandvik Bergmann Rose Marie Moss Trond Engjom Eirik S øfteland Source Type: research

Gallbladder wall thickening in patients with IgG4-related diseases, with special emphasis on IgG4-related cholecystitis
CONCLUSIONS: Most cases of GB wall thickening in IgG4-related diseases are closely associated with IgG4-related sclerosing cholangitis and may be a manifestation of IgG4-related disease throughout the biliary tract, including the bile duct, cystic duct, and GB.PMID:34486468 | DOI:10.1080/00365521.2021.1971758 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 6, 2021 Category: Gastroenterology Authors: Koji Watanabe Terumi Kamisawa Kazuro Chiba Masataka Kikuyama Jun Nakahodo Yoshinori Igarashi Source Type: research

Detection of a novel antigen for Crohn's disease
Scand J Gastroenterol. 2021 Sep 6:1-7. doi: 10.1080/00365521.2021.1973088. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Accurate serological assays are desirable for the diagnosis of inflammatory bowel disease (IBD). We identify an antigen-like substance called Crohn's disease (CD) antibody binding polypeptide (CABP). As a serological marker, anti-CABP may contribute to the diagnosis of IBD. The present study aims to evaluate the clinical role of anti-CABP as a serological antibody for IBD.METHODS: Using enzyme-linked immunosorbent assay (ELISA), serum anti-CABP, anti-Saccharomyces cerevisiae antibody (ASCA) and peri...
Source: Scandinavian Journal of Gastroenterology - September 6, 2021 Category: Gastroenterology Authors: Yarong Wei Tingting Chen Wu Yang Huihui Li Chen Fang Qiuyuan Liu Yonghao Chen Qiao Mei Source Type: research

Efficacy of empiric esophageal dilation in patients with non-obstructive dysphagia: systematic review and meta-analysis
CONCLUSIONS: Our meta-analysis does not support the use of empiric esophageal dilation in patients with non-obstructive dysphagia. More studies are required to confirm these findings.PMID:34477033 | DOI:10.1080/00365521.2021.1971288 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 3, 2021 Category: Gastroenterology Authors: Faisal Kamal Muhammad Ali Khan Wade Lee-Smith Sachit Sharma Dawit Jowhar Umer Farooq Ashu Acharya Abdul Kouanda Zaid Imam Nazneen Ahmed Collin Henry Nasir Saleem Craig Munroe Colin W Howden Source Type: research

Acute pancreatitis in patients with COVID-19 is more severe and lethal: a systematic review and meta-analysis
CONCLUSION: Current evidence suggests that COVID-19 adversely impacts the morbidity and mortality associated with acute pancreatitis. SARS-CoV-2 may be a causative agent for acute pancreatitis. Further population-based studies are needed to confirm or refute these findings.PMID:34465256 | DOI:10.1080/00365521.2021.1971757 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - September 1, 2021 Category: Gastroenterology Authors: Hemant Raj Mutneja Abhishek Bhurwal Shilpa Arora Akshay Goel Ishaan Vohra Bashar M Attar Source Type: research

Association between abuse and neglect with functional constipation and irritable bowel syndrome in adolescents
Scand J Gastroenterol. 2021 Sep 1:1-6. doi: 10.1080/00365521.2021.1923059. Online ahead of print.ABSTRACTOBJECTIVES: To evaluate the association between violence exposure, abuse, and neglect victimization with functional constipation and irritable bowel syndrome in adolescents.METHODS: Observational cross-sectional case-control study conducted with adolescents from two public schools in the municipality of Osasco, metropolitan region of São Paulo, Brazil. A self-administered questionnaire validated for Brazilian Portuguese Child Abuse Screening Tools - Children's version (ICAST-C) was used to screen the different ty...
Source: Scandinavian Journal of Gastroenterology - September 1, 2021 Category: Gastroenterology Authors: Camila Nunes Thomaz de Almeida Soraia Tahan Kelsy Nema Areco Mauro Batista de Morais Source Type: research

Predictors of infliximab-induced deep remission in treatment-na ïve patients with isolated small bowel Crohn's disease
CONCLUSIONS: In treatment-naïve patients with isolated small bowel CD, a moderate-to-severe endoscopic disease and the presence of fibrofatty proliferation at baseline reduce the possibility of infliximab-induced deep remission. Patients with such risk factors may need more aggressive treatment at the beginning of induction therapy to promote deep remission at an early stage.PMID:34461786 | DOI:10.1080/00365521.2021.1971759 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - August 31, 2021 Category: Gastroenterology Authors: Ze-Min Han Bing-Xia Chen Qian Zhou Hong-Bin Liu Pei-Chun Xu Fa-Chao Zhi Source Type: research

Is there a role for growth status in distinguishing gallbladder adenomas from cholesterol polyps? - A retrospective study based on 520 cholecystectomy patients
CONCLUSION: Growth status was not a valuable modality to distinguishing gallbladder adenomas from cholesterol polyps. Risk factors such as age, polyp size, and solitary polyp were effective in predicting adenomas.PMID:34461797 | DOI:10.1080/00365521.2021.1970220 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - August 31, 2021 Category: Gastroenterology Authors: Wenqing Bao Anan Xu Shubin Ni Bo Wang Humaira Urmi Bin Zhao Yongmei You Hai Hu Source Type: research