Well-being and dietary adherence in patients with coeliac disease depending on follow-up
Scand J Gastroenterol. 2021 Feb 23:1-10. doi: 10.1080/00365521.2021.1889024. Online ahead of print.ABSTRACTOBJECTIVE: It is not clear how follow-up of coeliac disease should be optimally organised. In Malmö, Sweden, patients are followed up by general practitioners (GP), but in Linköping by gastroenterologists (GE). The aim of this study was to investigate if there were any differences in well-being and dietary adherence depending on type of follow-up.METHODS: All adult patients with newly diagnosed biopsy-verified coeliac disease in the cities between 2010 and 2014 were offered to participate. Data was retrieved...
Source: Scandinavian Journal of Gastroenterology - February 23, 2021 Category: Gastroenterology Authors: Jesper Lexner Henrik Hjortswang Rickard Ekesbo Klas Sj öberg Source Type: research

Effectiveness of infliximab treatment of complex idiopathic anal fistulas
CONCLUSIONS: Infliximab treatment may be considered a supplement to repeated curettage and setondrainage in the management of selected, complex idiopathic anal fistulas. Such combined treatment may make otherwise refractory fistulas amenable to definitive closure attempts.PMID:33617372 | DOI:10.1080/00365521.2021.1879246 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 22, 2021 Category: Gastroenterology Authors: Anders Dige Andreas Nordholm-Carstensen Kikke Hagen Helene Tarri Hougaard Klaus Krogh J ørgen Agnholt Bodil Ginnerup Pedersen Lilli Lundby Source Type: research

Swedish national guidelines for chronic pancreatitis
Scand J Gastroenterol. 2021 Feb 22:1-15. doi: 10.1080/00365521.2021.1881815. Online ahead of print.ABSTRACTChronic pancreatitis (CP) should be suspected in the case of recurrent upper abdominal pain of unknown origin and/or clinical signs of exocrine pancreatic insufficiency (EPI). Alcohol is the most common etiological factor associated with CP, others being smoking, male gender, and hereditary forms. CP is often associated with recurrent episodes of acute exacerbations. As of today, there is no accepted clinical definition of CP. However, irreversible morphological changes within the pancreas often occur, including dilat...
Source: Scandinavian Journal of Gastroenterology - February 22, 2021 Category: Gastroenterology Authors: Roland Andersson Johannes-Matthias L öhr Working Group for Chronic Pancreatitis Guidelines (Sweden) Source Type: research

The role of female endoscopists: are women gastroenterologists better at obtaining biopsies for celiac disease than men?
CONCLUSIONS: Physician sex-based differences in biopsy patterns may exist. PMID: 33599184 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 20, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Interferon lambda 4 genotype and pathway in alcoholic hepatitis.
CONCLUSIONS: The IFN lambda 4 pathway seems involved in the acute disease processes of alcoholic hepatitis and patients without IFN lambda expression seem to have a short-term survival benefit. PMID: 33602032 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 20, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Early Infliximab in Crohn's is associated with decreased intestinal surgery and similar health care costs.
CONCLUSION: EUI in pCD is associated with an increased likelihood of being diagnosed in more recent years, less intestinal surgery and a trend toward decreased hospital admissions than LUI. PMID: 33595389 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 19, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis.
CONCLUSIONS: Neopterin and KT-ratio were elevated in PSC and associated with liver transplantation-free survival in two independent PSC cohorts, highlighting a possible role of interferon gamma-driven inflammation in the pathogenesis. However, the lack of association with survival in one of the cohorts reduces the potential clinical value of neopterin and KT-ratioas biomarkers and highlights the need to validate new biomarkers in PSC in multiple cohorts. PMID: 33583308 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 17, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Reliability of anti-tissue transglutaminase antibodies in children with malnutrition.
CONCLUSIONS: Malnutrition does not affect anti-TG2 IgA levels in children. However, anti-TG2 IgG levels increase in children suffering from malnutrition. When examining celiac disease, especially in people with a background IgA deficiency, doctors should consider whether malnutrition may be the cause of the increase in serum anti-TG2 IgG levels without celiac disease. PMID: 33590788 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 17, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

A Danish population-based case series of patients with liver cirrhosis and coronavirus disease 2019.
Authors: Attauabi M, Burisch J, Bendtsen F, Kimer N Abstract OBJECTIVES: Coronavirus disease 2019 (COVID-19) is an ongoing major health emergency, but its occurrence and clinical impact on patients withliver cirrhosis is unknown. Therefore, we conducted a population-based study of 2.6 million Danish citizens investigating the occurrence and impact of COVID-19 in patients with liver cirrhosis. MATERIALS AND METHODS: A prospective population-based cohort study was conducted in the Capital Region of Denmark and Region Zealand in the study period between 1 March 2020 up until 31 May 2020, with the only eligibility ...
Source: Scandinavian Journal of Gastroenterology - February 17, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Malignancy in elective cholecystectomy due to gallbladder polyps or thickened gallbladder wall: a single-centre experience.
Authors: Björk D, Bartholomä W, Hasselgren K, Edholm D, Björnsson B, Lundgren L Abstract INTRODUCTION: Gallbladder cancer is a rare but aggressive malignancy. Surgical resection is recommended for gallbladder polyps ≥10 mm. For gallbladder wall thickening, resection is recommended if malignancy cannot be excluded. The incidence of gallbladder malignancy after cholecystectomy with indications of polyps or wall thickening in the Swedish population is not known. MATERIAL/METHODS: A retrospective study was performed at Linköping University Hospital and included patients who underwent c...
Source: Scandinavian Journal of Gastroenterology - February 17, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

The value of Metronidazole in the management of acute radiation proctitis.
Authors: Babakhanlou R, Larkin K PMID: 33577737 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 14, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Treatment and outcome of ulcerative colitis during the first 10 years after diagnosis in a prospectively followed population-based cohort.
CONCLUSIONS: A frequent use of IMMs and biologicals during 10 years, can result in a low need for colectomy without increased mortality compared to previous reports. PMID: 33577739 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 14, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

A population-based study on time trends of hemoglobin in primary care comparing prediagnostic colorectal cancer patients vs age- and sex-matched controls.
CONCLUSION: The findings indicate a potential for Hb trends to inform the diagnostic process of CRC but whether it will translate into any clinical advantage is yet uncertain. PMID: 33555210 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Cisplatin/capecitabine with intensity-modulated radiation therapy in anal squamous cell carcinoma: a preliminary study.
CONCLUSION: In our study, cisplatin/capecitabine combined with IMRT was safe in ASCC patients, with favorable efficacy as an alternative, and is expected to be explored in study with larger sample. PMID: 33556252 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Risk factors associated with missed colorectal lesions in colonoscopy and impact of colonoscopy with anesthesia on miss rate.
Authors: Dong H, Ren Y, Jiang B Abstract OBJECTIVES: To systematically determine the miss rate and risk factors for polyps, adenomas and advanced adenomas in the same population, and to further analyze the impact of colonoscopy with anesthesia on miss rate. METHODS: We retrospectively analyzed the information of the patients undergoing the second colonoscopy within 1 year after their first. The patient and lesion miss rate were calculated. The patient and lesion features of missed lesion were compared with non-missed lesion. Finally, the patients were divided into anesthesia group and without anesthesia ...
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Serum levels of endotrophin are associated with nonalcoholic steatohepatitis.
Authors: Hagström H, Bu D, Nasr P, Ekstedt M, Hegmar H, Kechagias S, Zhang N, An Z, Stål P, Scherer PE Abstract BACKGROUND AND AIMS: There are no currently available biomarkers that can accurately indicate the presence of non-alcoholic steatohepatitis (NASH). We investigated the association between endotrophin, a cleavage product of collagen type 6α3, and disease severity in patients with non-alcoholic fatty liver disease (NAFLD). METHODS: We measured serum endotrophin levels in 211 patients with NAFLD and nine healthy controls. Liver biopsy data was available for 141 (67%) of the patients. Ass...
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Endoscopic submucosal dissection (ESD): how do Western endoscopists value animal models?
CONCLUSIONS: Western endoscopists have extensive endoscopic experience before starting ESD. The majority had pre-clinical training with ex vivo and live animal models and more than half are acting as trainers of other endoscopists with these models. Animal models are considered very useful and deemed a prerequisite before clinical practice by the majority of the endoscopists. PMID: 33556257 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Efficacy of a novel ultra-sharp dilation device for dilating bare metal stent mesh in patients with hilar malignant biliary obstruction.
Authors: Kato S, Kuwatani M, Kawakubo K, Furukawa R, Hirata K, Takishin Y, Hirata H, Sakamoto N Abstract The placement of additional stents in patients with hilar malignant biliary obstruction can be challenging when a metal stent already exists because occasionally, the catheter and delivery system of the additional stent cannot pass through the mesh of the formerly placed stent. We studied ten consecutive patients with hilar malignant biliary obstruction who underwent mesh dilation using a novel ultra-sharp dilation device (ES dilator) to assess the efficacy and safety of the ES dilator for mesh dilation. Mesh di...
Source: Scandinavian Journal of Gastroenterology - February 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Factors influencing diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic and biliary tumors.
CONCLUSIONS: The learning curve for EUS-FNA may be longer and a considerable number of procedures are needed to achieve high diagnostic accuracy in the absence of ROSE. However, the use of FNB needles and the simultaneous sampling of primary and metastatic lesions can rapidly improve the diagnostic accuracy of the procedure. PMID: 33539716 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 6, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Colonic paracellular permeability and circulating zonulin-related proteins.
CONCLUSIONS: Our study suggests that neither circulating zonulin nor pre-HP2 mirror colonic permeability. Our data corroborate previous reports showing the inability of the Cusabio zonulin kit to target zonulin and highlights that the results of studies using this kit must be re-examined with caution. PMID: 33535002 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - February 4, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Visceral fat area to appendicular muscle mass ratio as a predictor for nonalcoholic fatty liver disease independent of obesity.
Authors: Shi YX, Chen XY, Qiu HN, Jiang WR, Zhang MY, Huang YP, Ji YP, Zhang S, Li CJ, Lin JN Abstract OBJECTIVE: Obesity and sarcopenia are known to be closely related to nonalcoholic fatty liver disease (NAFLD). We attempted to explore the combined influence of fat and muscle tissue on NAFLD by using visceral fat area to appendicular muscle mass ratio (VAR) as a novel parameter. MATERIAL AND METHODS: In this cross-sectional study, a total of 3255 adults (1399 men and 1856 women) coming for a health examination were enrolled. NAFLD was diagnosed using ultrasound and VAR was measured by bioelectrical impedance ...
Source: Scandinavian Journal of Gastroenterology - February 4, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Long-term outcome of patients with acute ulcerative colitis after first course of intravenous corticosteroids.
CONCLUSION: Although intravenous Cs were efficient in inducing clinical response in patients with severe acute UC, only one fifth maintained remission in the long term. Two-thirds of patients required further Cs and the overall colectomy rate remained at 26%. High relapse rate indicates the need for closer monitoring of these patients. Enhancement of maintenance therapy should be considered at early stage after acute flare. PMID: 33496198 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 28, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Low serum vitamin D level associated with incident advanced liver disease in the general population - a prospective study.
Authors: Männistö V, Jääskeläinen T, Färkkilä M, Jula A, Männistö S, Lundqvist A, Zeller T, Blankenberg S, Salomaa V, Perola M, Åberg F Abstract BACKGROUND: Vitamin D deficiency is a common finding in chronic liver disease. It has also been linked to the pathogenesis of non-alcoholic fatty liver disease, hepatic fibrogenesis, decompensation and hepatocellular carcinoma. AIMS: We analyzed whether serum vitamin D is associated with incident advanced liver disease in the general population. METHODS: Serum 25-hydroxyvitamin D was measured in 13807 individuals p...
Source: Scandinavian Journal of Gastroenterology - January 24, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

EIF3B promotes cancer progression in pancreatic cancer.
CONCLUSIONS: Our data uncovered the oncogenic role of EIF3B in pancreatic cancer. PMID: 33459066 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 21, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Chronic gastritis according to age and Helicobacter pylori in Thailand: histopathological patterns.
CONCLUSION: Overall chronic gastritis is common in dyspeptic patients without visible lesions. Prevalence, grading, and severity of chronic gastritis increase with age and Hp infection. Temporal changes of the gastric mucosa are caused by aging rather than by Hp alone. PMID: 33459087 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 21, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Nonalcoholic fatty liver disease and the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis: the hidden danger.
CONCLUSION: NAFLD was shown to be a risk factor for PEP. Therefore, we suggest considering prophylactic pancreatic stenting and/or NSAID's suppositories among these patients. PMID: 33460351 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 21, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Clinical efficacy of first and second series of peptide receptor radionuclide therapy in patients with neuroendocrine neoplasm: a cohort study.
Authors: Zacho MD, Iversen P, Villadsen GE, Baunwall SMD, Arveschoug AK, Grønbaek H, Dam G Abstract OBJECTIVES: Peptide receptor radionuclide therapy (PRRT) is an established treatment for metastatic neuroendocrine neoplasms (NEN). However, only limited data exists for the effect of multiple series of PRRT. The aim of this study was to investigate PFS and OS inNEN patients treated with multiple series of PRRT conforming to the ENETS treatment protocol. METHODS: We included all patients with gastrointestinal (GI), pancreatic and bronchopulmonary (BP) NEN treated with PRRT from 2008 to 2018. We used Kaplan...
Source: Scandinavian Journal of Gastroenterology - January 21, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Endoscopic resection of local recurrences of diminutive polyps by cold forceps polypectomy.
Authors: Kuwai T, Yamada T, Toyokawa T, Kudo T, Esaka N, Ohta H, Yamashita H, Hosoda Y, Watanabe N, Harada N Abstract OBJECTIVES: Cold forceps polypectomy (CFP) is an effective treatment for diminutive colorectal polyps. However, polyps occasionally recur, and there is no consensus on their long-term clinical management. Therefore, we investigated the short- and long-term clinical outcomes of re-CFP for recurrent diminutive colorectal polyps. MATERIALS AND METHODS: This was a follow-up of a multicenter, prospective study investigating the clinical outcomes of diminutive colorectal polyps excised by CFP with nar...
Source: Scandinavian Journal of Gastroenterology - January 15, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Survival and morbidity following stereotactic radiotherapy of hepatocellular carcinoma: a ten-year, single institution experience.
CONCLUSION: SABR provides high local control to inoperable HCC. SABR can be delivered safely even after previous liver-directed therapies and subsequent therapies are feasible after treatment with SABR. Despite excellent local control, disease progression outside of the irradiated site remains prominent. Further studies are warranted to examine combined therapy approaches to maximize disease control. PMID: 33430663 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 14, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

The diagnostic value of C-reactive protein for predicting pancreatic fistula following pancreatoduodenectomy.
CONCLUSION: Our findings indicate that small rises in C-reactive protein during the first postoperative days after pancreaticoduodenectomy are associated with an increased risk of developing postoperative pancreatic fistula. PMID: 33427522 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 13, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

White light and/or magnifying endoscopy with narrow band imaging for superficial nonampullary duodenal epithelial tumors.
Authors: Kakushima N, Yoshida M, Takizawa K, Yabuuchi Y, Kawata N, Kishida Y, Ito S, Imai K, Hotta K, Ishiwatari H, Matsubayashi H, Ono H Abstract BACKGROUND AND AIM: A reliable optical diagnosis of superficial nonampullary duodenal epithelial tumors (SNADETs) to guide optimal treatment strategy is lacking. The aim of this study was to simulate the treatment outcomes based on optical diagnosis using white light imaging (WLI) or magnifying endoscopy with narrow band imaging (MNBI) and to evaluate the method to extract optimal lesions suitable for cold snare polypectomy (CSP) or not. METHODS: We created a decisio...
Source: Scandinavian Journal of Gastroenterology - January 10, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Accuracy of Finnish Cancer Registry colorectal cancer data: a comparison between registry data and clinical records.
CONCLUSION: The FCR data had good accuracy regarding tumour characteristics, but poor accuracy in treatment information. The main reason for this suboptimal accuracy was missing CRFs from treating clinicians. Awareness of these findings is crucial when research and decision making is based on FCR data. Measures have since been taken to improve the completeness of FCR recording. PMID: 33403883 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 8, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Exploration of endoscopic findings and risk factors of early gastric cancer after eradication of Helicobacter pylori.
Authors: Yan X, Hu X, Duan B, Zhang X, Pan J, Fu J, Xu M, Xu Q Abstract AIM: To explore the endoscopic features and risk factors of early gastric cancer (EGC) after eradication of Helicobacter pylori (H. pylori). METHODS: A total of 1961 patients who underwent esophago-gastro-duodenoscopy (EGD) with a history of successful H. pylori eradication were enrolled in this multicenter research. Among them, 162 EGC lesions of 132 patients were detected. The endoscopic features and risk factors of post-eradication EGC were explored. RESULTS: Severe atrophy (75.3% vs. 16.7%, p value
Source: Scandinavian Journal of Gastroenterology - January 8, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Impact of the Crohn's disease digestive damage score (L émann Index) on the perioperative course in patients with Crohn's disease and ileocolic anastomosis.
CONCLUSIONS: The Lémann Index might affect surgical decision making but is not linearly associated with postoperative morbidity. However, medium indices (3-10) - mainly accounted for by high amounts of intraabdominal active Crohn`s lesions - showed significantly higher rates of complications, potentially defining a group at risk. PMID: 33410352 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 8, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Prognosis of hepatocellular carcinoma patients diagnosed under regular surveillance: potential implications for surveillance goal.
CONCLUSIONS: When tumors of ≤3 cm were detected and had no vascular invasion, curative-intent treatment was applied for most patients and showed excellent OS. This finding suggests that to detect tumors of
Source: Scandinavian Journal of Gastroenterology - January 7, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Antibiotic prophylaxis in ERCP with failed cannulation.
Authors: Olsson G, Enochsson L, Swahn F, Andersson B Abstract OBJECTIVES: Endoscopic retrograde cholangiopancreatography (ERCP) with failed biliary cannulation is associated with a high rate of adverse events, but the role of prophylactic antibiotics remains unclear. The primary aim was to investigate if prophylactically administered antibiotics affect the frequency of overall adverse complications in patients where biliary cannulation fails during ERCP. The secondary aim was to investigate if specific infectious complications, also were affected by the antibiotic prophylaxis. MATERIALS AND METHODS: We analysed...
Source: Scandinavian Journal of Gastroenterology - January 7, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Hepatitis B virus infection increases the risk of pancreatic cancer: a meta-analysis.
CONCLUSIONS: The findings of this meta-analysis suggest that HBV infections may increase the risk of pancreatic cancer under most conditions, while there remains some doubt when comparison is made between European and Oceania patients. PMID: 33399501 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 7, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Oral indigo carmine for the detection of colon adenoma.
CONCLUSION: The routine use of oral indigo carmine does not lead to a higher ADR despite the higher MAP. PMID: 33378628 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 1, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Super selective arterial embolization to treat radiation-induced hemorrhagic gastritis: a case report and review of the literature.
Authors: Mossa M, Neri B, Scarozza P, Del Vecchio Blanco G, Giannelli M, Argirò R, Di Carlo S, Monteleone G, Petruzziello C Abstract Radiation-induced hemorrhagic gastritis (RIHG) is a rare but potentially fatal event following radiotherapy for locally advanced gastric cancer; the treatment of this condition is not standardized. Only few cases of RIHG have been reported, treated with different therapeutic approaches. Here we report the case of a 79-year-old patient who underwent subtotal gastrectomy for gastric cancer, followed by adjuvant chemo-radiotherapy. Approximately 3 months after the end of the treat...
Source: Scandinavian Journal of Gastroenterology - January 1, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Correction.
Authors: PMID: 33380232 [PubMed] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 1, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Appropriate endoscopic treatment selection and surveillance for superficial non-ampullary duodenal epithelial tumors.
CONCLUSIONS: While tumors ≤10 mm seem to be good indications for endoscopic mucosal resection, ESD should be considered for larger tumors to better achieve complete resection. Patients with submucosal invasive carcinomas have a great risk of cancer death. Therefore, a close follow-up and an additional treatment are desirable. PMID: 33382001 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - January 1, 2021 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

The bleeding risk after endoscopic ultrasound-guided puncture of pancreatic masses.
Authors: Razpotnik M, Bota S, Kutilek M, Essler G, Weber-Eibel J, Maieron A, Peck-Radosavljevic M Abstract BACKGROUND: Although EUS-fine-needle aspiration (FNA) is considered to be safe, there are limited studies on adverse events of fine-needle biopsy (FNB). AIM: To compare the bleeding rate of EUS-FNA and EUS-FNB of solid and cystic pancreatic masses. METHODS: Our retrospective study included EUS-FNA/FNB of solid and cystic pancreatic masses performed between 02/2017-03/2019 in Klinikum Klagenfurt and 11/2018-03/2019 in University Hospital St. Pölten, Austria. Minor bleeding was defined as an event w...
Source: Scandinavian Journal of Gastroenterology - December 29, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Intraperitoneal microdialysis detects intestinal leakage earlier than hemodynamic surveillance and systemic inflammation in a pig model.
Authors: Pischke SE, Hødnebø S, Wester T, Haugaa H, Kvernebo K, Barratt-Due A, Tønnessen TI Abstract OBJECTIVE: Anastomotic leakage is a common complication following large abdominal surgery, often developing to life-threatening abdominal sepsis due to late diagnosis. Currently, diagnostics rely on systemic hemodynamic and infection monitoring. We hypothesized that intraperitoneal microdialysis allows detection of peritonitis prior to changes in standard clinical parameters in a pig model. MATERIALS AND METHODS: We included six pigs; five underwent intraperitoneal fecal contamination, one h...
Source: Scandinavian Journal of Gastroenterology - December 29, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Pancreatic atrophy and exocrine insufficiency associate with the presence of diabetes in chronic pancreatitis patients, but additional mediators are operative.
CONCLUSION: Pancreatic atrophy and exocrine insufficiency are present in most CP patients with diabetes, but additional mediators seem to be operative in post pancreatitis diabetes mellitus. PMID: 33369483 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 29, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Tacrolimus as second-line therapy in acute severe autoimmune hepatitis.
Authors: Efe C PMID: 33369499 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 29, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Clinically relevant thyroid disorders and inflammatory bowel disease are inversely related: a retrospective case-control study.
CONCLUSIONS: Overall, in our study, the risk of TDs was lower in IBD patients. To assess routinely hormones and/or thyroid gland imaging in the absence of clinical signs or symptoms seems unnecessary in IBD patients, at least in our geographic area. PMID: 33327797 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 19, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and females.
Authors: Helgadóttir H, Lund SH, Gizurarson S, Waldum H, Björnsson ES Abstract OBJECTIVE: Gastrin elevation secondary to proton pump inhibitor (PPI) therapy is well documented. Recent studies have demonstrated a sex-related difference where females on PPIs have significantly higher baseline gastrin levels than males. The aim of the study was to analyse the pharmacokinetics of esomeprazole and short-term effect on serum gastrin levels and evaluate potential sex-related difference. MATERIALS AND METHODS: Healthy volunteers received 40 mg of esomeprazole daily for five days. After the 1st and 5t...
Source: Scandinavian Journal of Gastroenterology - December 19, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Endoscopic negative pressure therapy for leaks with large cavities in the upper gastrointestinal tract: is it a feasible therapeutic option?
CONCLUSION: Based on the data of our case series, we conclude that ENPT is a feasible and promising therapeutic option for upper GI defects with contact to large cavities. PMID: 33332197 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 19, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Treatment profile and long-term outcome of intensive care unit-admitted patients with liver cirrhosis or other liver disease in relation to alcohol consumption.
CONCLUSIONS: We report no significant impact of alcohol consumption on the ICU treatment profile or mortality of patients with cirrhosis or other liver disease. The high mortality underlines the importance of preventive measures after ICU admission. PMID: 33332198 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 19, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research

Protective effect of proton pump inhibitors and potassium competitive acid blockers against post-gastric endoscopic submucosal dissection bleeding: a single-center, propensity score-matched analysis.
CONCLUSIONS: The incidence of post gastric ESD bleeding is not different between patients treated with PPI and patients treated with P-CAB. Antithrombotic therapy is an independent risk factor associated with post-ESD bleeding. PMID: 33332216 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - December 19, 2020 Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research