Evaluation of gallbladder contractility and Doppler findings in patients with irritable bowel syndrome; a case-control study
CONCLUSION: IBS patients have a higher emptying fraction and lower change in SMA RI compared to healthy controls. Further studies with larger sample size, inclusion of patients with different coexisting conditions and subtypes of IBS and combining colon transit study with gallbladder ejection fraction evaluation can be used to further provide more meaning to this study.PMID:38031926 | DOI:10.1080/00365521.2023.2287989 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 30, 2023 Category: Gastroenterology Authors: Samin Alihosseini Farzaneh Khodaei Mehran Jaberinezhad Mojtaba Azari Maghsoud Ezzati Khatab Hedieh Akhlaghi Nima Ghanini Mohammad Kazem Tarzamni Elham Eghbali Source Type: research

Hyperplastic polyp-like adenoma: a subtype of colonic adenoma with a proliferative zone confined to the lower two-thirds of the crypt
CONCLUSION: Colonic adenomas with proliferative zones confined to the lower two-thirds of the crypt often appear as diminutive, hyperplastic polyps.PMID:38031937 | DOI:10.1080/00365521.2023.2285228 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 30, 2023 Category: Gastroenterology Authors: Toshihiro Nishizawa Hidenobu Watanabe Shuntaro Yoshida Tatsuya Matsuno Hideki Nakagawa Kenji Tamada Hirotoshi Ebinuma Mitsuhiro Fujishiro Yutaka Saito Osamu Toyoshima Source Type: research

Prognosis of EBV-positive gastric cancer with lymphoid stroma: systematic review and meta-analysis
CONCLUSIONS: EBV-positive GCLS tends to have lower mortality, suggesting that detection of EBV infection is necessary to predict prognosis of GCLS.PMID:38032298 | DOI:10.1080/00365521.2023.2286194 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 30, 2023 Category: Gastroenterology Authors: Tianxin Ying Jie Chen Jiyu Song Yi Zhou Banghe Bao Liduan Zheng Source Type: research

The prognostic value of age-adjusted Charlson comorbidity index in laparoscopic resection for hilar cholangiocarcinoma
We examined ACCI's association with OS and RFS using Cox regression analyses and developed an ACCI-based nomogram for survival prediction. Our analysis revealed that higher ACCI scores (ACCI > 4.0) (HR = 2.14, 95%CI: 1.37-3.34) were identified as an independent risk factor significantly affecting both OS and RFS in postoperative patients with hilar cholangiocarcinoma (p < 0.05). TNM stage III-IV (HR = 7.42, 95%CI: 3.11-17.68), not undergoing R0 resection (HR = 1.58, 95%CI: 1.01-2.46), hemorrhage quantity > 350 mL (HR = 1.92, 95%CI: 1.24-2.97), and not receiving chemotherapy (HR = 1.89, 95%CI: 1.21-2.95) were also ...
Source: Scandinavian Journal of Gastroenterology - November 29, 2023 Category: Gastroenterology Authors: Chiyu Cai Lianyuan Tao Dongxiao Li Liancai Wang Erwei Xiao Guanbin Luo Zhuangzhuang Yan Yanbo Wang Deyu Li Source Type: research

Mendelian randomization analysis reveals the impact of physical and occupational activities on the risk of gastroesophageal reflux disease and Barrett's esophagus
CONCLUSIONS: The findings indicated that strenuous sports or other forms of exercise could lower the likelihood of GERD/BE, while excessive physical strain in the workplace, prolonged periods of standing or walking, and shift work could raise the risk of GERD/BE. Acknowledging this risk and implementing suitable measures can contribute to the prevention of GERD and BE, thus mitigating the associated health burden.PMID:38009009 | DOI:10.1080/00365521.2023.2287416 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 27, 2023 Category: Gastroenterology Authors: Li Wan Hong-Zhou Zuo De-Wei Li Source Type: research

Switching from intravenous to subcutaneous infliximab and vedolizumab in patients with inflammatory bowel disease: impact on trough levels, day hospital visits, and medical expenses
CONCLUSIONS: IV and SC IFX and VDZ are equally effective in maintaining remission in IBD, but SC administration reduces day hospital visits and results in higher trough levels. SC VDZ is less and SC IFX more expensive than IV therapy. Further studies are needed to assess optimal dosing and separate trough levels for SC therapy.PMID:38006219 | DOI:10.1080/00365521.2023.2285229 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 25, 2023 Category: Gastroenterology Authors: Jenniina Harno-Tasihin Laura Siregar Mikko Paajanen Perttu Arkkila Jari Punkkinen Source Type: research

Microbial exposure during early life regulates development of bile duct inflammation
CONCLUSIONS: Microbial exposure during early life has a temporal impact on biliary tract inflammation in the NOD.c3c4 mouse model suggesting that age-sensitive interaction with commensal microbes have long-lasting effects on biliary immunity that can be of importance for human cholangiopathies.PMID:37997753 | DOI:10.1080/00365521.2023.2278423 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 24, 2023 Category: Gastroenterology Authors: Tine S Oldereid Xiaojun Jiang Jonas Øgaard Elisabeth Schrumpf J ørgen V Bjørnholt Henrik Rasmussen Espen Melum Source Type: research

ERCP for the initial management of malignant biliary obstruction - real world data on 596 procedures
CONCLUSIONS: ERCP has a high rate of clinical effect and technical success in the management of both distal extrahepatic and perihilar MBO. Our data indicate that ERCP is a valid option in the first-line management of MBO.PMID:37994406 | DOI:10.1080/00365521.2023.2282375 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 23, 2023 Category: Gastroenterology Authors: I M Mikalsen S Breder A W Medhus T Folseraas L Aabakken K V Ånonsen Source Type: research

Circulating cytokines and alcoholic liver disease: a two-sample bidirectional Mendelian randomization study
CONCLUSIONS: Our study supports that cytokines play a pivotal role in the pathogenesis of ALD. To determine the mechanisms and pathways of action of these biomarkers, further basic research is required to ensure their clinical suitability for preventing and treating ALD.PMID:37994815 | DOI:10.1080/00365521.2023.2286190 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 23, 2023 Category: Gastroenterology Authors: Duan Wu Ouyang Hao Weiye Hu Zhaorong Wu Linke Bian Hongye Wang Junfeng Zhu Source Type: research

ERCP for the initial management of malignant biliary obstruction - real world data on 596 procedures
CONCLUSIONS: ERCP has a high rate of clinical effect and technical success in the management of both distal extrahepatic and perihilar MBO. Our data indicate that ERCP is a valid option in the first-line management of MBO.PMID:37994406 | DOI:10.1080/00365521.2023.2282375 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 23, 2023 Category: Gastroenterology Authors: I M Mikalsen S Breder A W Medhus T Folseraas L Aabakken K V Ånonsen Source Type: research

Circulating cytokines and alcoholic liver disease: a two-sample bidirectional Mendelian randomization study
CONCLUSIONS: Our study supports that cytokines play a pivotal role in the pathogenesis of ALD. To determine the mechanisms and pathways of action of these biomarkers, further basic research is required to ensure their clinical suitability for preventing and treating ALD.PMID:37994815 | DOI:10.1080/00365521.2023.2286190 (Source: Scandinavian Journal of Gastroenterology)
Source: Scandinavian Journal of Gastroenterology - November 23, 2023 Category: Gastroenterology Authors: Duan Wu Ouyang Hao Weiye Hu Zhaorong Wu Linke Bian Hongye Wang Junfeng Zhu Source Type: research